Chemical Engineering Alumni/ae News Fall 2002 • Course X Room 66-350 • Fax: (617) 253-8992

FROM THE HEAD OF THE DEPARTMENT.... PBS Program Highlights an underlying fundamental science Griffith, Langer, pg. 6 Professor and exploiting the broad and rich set Robert C. of opportunities at the interfaces with Cain Foundation, Roos ’44, Armstrong many other disciplines on some of Evans Help Fund New Head, MIT the most exciting technologies of our Undergrad Lab Facility, pg. 20 Chemical times. MIT provides a truly excep- Photo: Stu Rosner Engineering tional environment for both of these, New Alliance Shares Biotech because of the uniform excellence of Strengths and Benefits, pg. 22 reetings from Department departments in other, related areas of Headquarters! Life in the science and engineering on campus. Gdepartment continues at an MIT’s strong commitment to life ALSO IN THIS ISSUE: exhilarating pace, with new develop- sciences, the outstanding biology ments occurring on many fronts. I am department at MIT, and the innovative News from the Head...... 1 grateful to have this opportunity to Biological Engineering Division touch on a few of the developments (co-directed by Professor Douglas Practice School News...... 2 in the department, and I invite you A. Lauffenburger from our depart- Awards Day 2002...... 4 to learn more from the rest of the ment) combine to make the appro- New Appointment/Promotions ...... 5 newsletter. priate and meaningful inclusion of biology possible in ways that would Cooney / New Deshpande Ctr...... 6 First a few highlights: the Depart- otherwise not be possible. In respond- Jensen Elected to NAE ...... 6 ment’s graduate and undergraduate ing to these two opportunities the Langer Wins “Triple Crown”...... 7 programs were both ranked number department has in the past two years one among chemical engineering revamped both its graduate and under- The MIT ChemE Connection ..... 13 departments in the most recent U.S. graduate curricula. ChE Faculty Lead MIT ISN...... 16 News & World Report academic News from the Alumni/ae ...... 18 survey; our faculty achieved a record The department has also been a $22 million research volume; we significant part of MIT’s international Named Lectures ...... 14 attracted the largest and most educational initiatives. As part of the Lauffenburger Wins Dual Honors21 outstanding incoming graduate class Cambridge MIT Institute (CMI), Alumni/ae Donors FY ’02 ...... 23 in recent memory for this academic the department has engaged in faculty year; we completed the renovation and student exchanges with the Research Briefs ...... 34 of the entire sub-basement of Build- University of Cambridge, and has GSC Activities ...... 36 ing 66 for a state-of-the-art undergrad- launched a joint Practice School uate teaching laboratory (See article Program (led by Professor T. Alan program combines faculty from the page 20); we renovated the graduate Hatton) that promises to add signifi- Departments of Chemical Engineering student offices and Walker Lounge cant value to both universities through and Biology at MIT with colleagues on the second floor of Building 66; interchange of ideas, people, and at the National University of Singa- and in the midst of all of this the collaborative development of new pore to create an entirely new, multi- we completely overhauled the under- subjects. Under the direction of pronged graduate program featuring graduate curriculum in the Depart- Professor Jackie Y. Ying, we have three different degrees. The depart- ment. It is a wonderful and exciting also launched one of the five core ment is also breaking new educational time in chemical engineering at MIT! programs that constitute the Singa- ground with its Doctor of Philosophy Two dominant intellectual themes pore-MIT Alliance (SMA), Molec- in Chemical Engineering (PhDCEP) are impacting our programs: weaving ular Engineering of Biological and biology throughout our curriculum as Chemical Systems (MEBCS). This HEAD see page 12 Practice School News

BY PROF. ALAN HATTON, PRACTICE SCHOOL DIRECTOR

he David H. Koch School

of Chemical Engineering ile TPractice continues to be an attractive option for many of our graduate students, and continues to be recognized as a unique educational Photo: PS F opportunity within the Department, attracting top students from around the country and around the world. A total of 35 students attended the stations, during the Fall ’01 through Summer ’02 sessions. With the strong support of our hosting compa- nies, we are able to continue to provide the diversity of experiences for our students that has traditionally characterized our program. Dinner with Summer 2002 General Mills Station Members (L side of The Practice School operated stations table from F to B): Andrew Kim (Asst. Station Director) , Joanna Yu, at a number of companies over this Stephany Lin, and Michael Rappel. (R side of table from F to B): past year. In Fall ’01, Paul Bryan Matthew Sokol, Yuhua Hu, Ramin Haghooie, and Uttam Kumbhat. Not directed the station at Cabot Corpo- pictured: Thomas Lada, and William Dalzell (Station Director). ration in Billerica MA, and John Friedly ran the General Mills station, courses here at MIT. This fall, we many of our industrial friends as a primarily in the Minneapolis area, completed a joint Practice School result of the terrible tragedy in New but with one project in Lodi, Califor- session under the CMI program, York in September of that year. nia. The Spring ’02 sessions were at BP Chemicals in Hull, UK, in conducted at M&M Mars Inc. in which the four Cambridge students However, we did hold the annual Elizabethtown, PA (John Friedly as were joined by four MIT students Practice School Awards Banquet, director) and the Minneapolis station under the supervision of Director where the Tester, Vivian, Wojtowicz at Cargill Inc. was supervised by Barry Johnston and Assistant Direc- and Rousseau Awards for Paul Bryan with some assistance tor Andrew Kim. By all accounts this Outstanding Performance in the from Anish Goel, who was in has been a very successful collabora- Practice School projects were training for his Directorship role at tion and we look forward to continu- presented. Recipients were Jacob the Mitsubishi Chemical station in ing it in coming years. The remainder Johnson and Stephen Fox, sharing Mizushima, Japan in the summer of of the fall will see us running stations the Vivian award; Lino Gonzalez, ’02. In Japan, Anish was aided by at General Mills facilities in Lodi whose enthusiasm for the program Associate Director Carlos Rinaldi – CA and Cedar Rapids IA, supervised earned him the Tester award; Megan both Anish and Carlos had recently by Brian Baynes. At these stations, LeMott, whose personal generosity, graduated with their PhDs from five MIT students will be joined by integrity and commitment to the MIT, and both were outstanding three students from Singapore under program won her the Wojtowicz students during their stints in the the auspices of the Singapore-MIT award; and Anand Sivaraman who Practice School some years earlier. Alliance program. received the Rousseau Award for Other stations over the summer were Leadership and Ethics in Chemical at KalKan in Vernon, CA (John The breadth of technical problems and Engineering Practice Friedly, Director), General Mills in environments provided by this large Cincinnati OH, Minneapolis MN and number of diverse companies afforded Beth Tuths who celebrated her Lodi CA (with Bill Dalzell running an excellent educational opportunity anniversary with the Practice School the show, assisted by Andrew Kim, for our students. We are grateful to as Administrative Assistant to the a recent MSCEP graduate) and Alker- these companies for their hosting of Director in June, 2002, must be mes in Cambridge MA (John Friedly our Practice School Stations. congratulated on her fine organization again). Last fall we initiated a joint of the Award Dinner, and on so very program with Cambridge University The Department’s Annual Informa- ably dealing with all those little (and under the Cambridge-MIT Institute tion Conference, to have been held in big!) problems with which the (CMI) in which four Cambridge October 2001, was cancelled because students participated in our core of the travel restrictions imposed on PS see facing page

2 2001 CHEMICAL ENGINEERING FELLOWSHIPS •••

Class of 1936 Fellows William & Margaret Hutchinson Bayer Fellow Dhananjay Dendukuri Rousseau Fellow Andy Wijaya Hiroyo Kawai Huan Zhang Jin Zhou Shell Doctoral Fellow Keith & Helen Rumbel Fellow Tyler Philip Martin Edwin R. Gilliland Fellow Benjamin N. Wang Sharon Yu-Wen Soong Chemical Engineering Practice Adel F. Sarofim Fellow School Fellows John Henry Grover Fellow Joel Forrest Moxley Alisa Mei-Jin Ching Mohit Rawat Hiroki Kaido Arch Scurlock Fellow Haas Family Fellow Manoj Viswanathan Exxon Mobil Fellow Sheng Li Chun-Yue Lee John C. Sluder Fellows Robert T. Haslam Fellow Beth P. Dubeck Procter & Gamble Fellow Yunpeng Yi Corey James Moore Jared K. Johnson

Frederick Holloway Fellow Howard Stern Fellow Rohm & Haas Fellow Zubair Anwar Chester K. Bai Malancha Gupta

George M. Keller Fellows Frank Hall Thorp/Class of 1936 Dumbros Fellow Brandon Shaw Blackwell Fellow Joseph L. Lowery Phuong Nguyen Jacob W. Albrecht Joseph Francis Shuga Dupont/MIT Alliance Fellows Rosemary Wojtowicz Fellow Erik Christian Allen George M. Keller Chevron Fellow Andrew John Allen William Shannan O’Shaughnessy Peter Alan Colvin Kris C. Wood Robert T. Billings Fellow David H. Koch Fellow Jason Fincher Haslam/Presidential Fellows Konrad Krupinski Hal S. Alper Tae Sup Lee/Whitaker Fellow Gregg Beckham Ralph Landau Fellows Daeyeon Lee Theis Forman Clarke Minggang She Jane Yevgeniya Rempel Christopher Patrick Tommaso George M. Morrow III Fellow Jodie L. Lutkenhaus Benjamin Ragan Waters Bernat Olle Wilson Mok Sheryl Yu Villa Brian Curtis Stephenson Alfred Wechsler Fellow Jerry & Geraldine McAfee Fellows Amy Lewis Norman B. Leventhal Fellow Neil Kumar Ana M. Acosta Cindy Ren Alkermes Fellows Sanjoy Sircar Ryan Bennett NDSEG Fellow Smeet Prakash Deshmukh Ginger Chao Reid & Williams Fellow Ajay Selot Aruna Mohan Presidential Fellows ATOFINA/Class of 1936 Fellow Micah J. Green Charles & Hilda Roddey Fellow Kerry A. Bentley Margaret Ruth Horton Yu Pu Mark Philip-Walter Styczynski

PS from facing page 2001-2002 Practice School Awards for Outstanding Performance Practice School Directors and students challenge her, and for making it look William C. Rousseau Award Jeffereson W. Tester Award so easy.

This has been a stimulating year Rosemary J. Wojtowicz Award for the Practice School, and we J. Edward Vivian Award look forward to continuing our devel- opment and testing of innovative approaches to station operations over Congratulations to all for their the next year to ensure that our students get the best education they dedication and fine contributions! can!•••

3 Awards Day BY ANNE FOWLER, CHEME STUDENT OFFICE

he annual Awards Ceremony 3rd year graduate student from North The Outstanding Employee Award for the Department of Chemical East, PA for her work with 10.302 in was pre- TEngineering was held on the fall. Also recognized was sented to Photo: Gregory Sands Monday, May 13, 2002 in Gilliland Matthew Lazzara, a 5th year Susan Auditorium. Professor and Depart- graduate student from Temple Lanza, (R) ment Head, Robert C. Armstrong, Terrace, FL for his exceptional work an admin- presided and the following awards as a Graduate Instructor for 10.302. istrative were presented: assistant Every Monday two 3rd-year graduate for Juniors Bukola Aina from Philadel- students present the progress of their Professors

phia, PA, and David Yin from Tyler, research Photo: Gregory Sands William TX received Merck Fellowships for for peer Green, the upcoming academic year. evaluation. George Stephanopoulos and Daniel Two grad- Wang. She was acknowledged for her The Goldwater Scholarship is given uate stu- exceptional dedication to these profes- out annually to one Chemical Engi- dents were sors, their students and the department neering undergraduate in the United recognized as a whole. States. This year MIT junior, Bradley for giving Olsen from Brooklyn Park, MN was outstand- The Outstanding Faculty Award the winner of this prestigious award. ing semi- from the graduate students was nars. This presented by Jason Kralj, and went The recipient of the Dow Chemical year rec- to Professor Daniel Blankschtein. Company Outstanding Junior ognition Bradley Olsen presented the Award was also Bradley Olsen went to Geoffrey Moeser (Above L) undergraduate Outstanding Faculty for his balanced record of achieve- from Burlington, Ontario for his Award to Professor C. Michael Mohr. ment in academics and campus seminar during the fall term, and professional Kevin Dorfman (Above R) from Nominations for the Individual and social Bensalam, PA for his seminar during Accomplishment Citation were organiza- the spring term. requested in the month of April and tions, as the recipient of the citation was Annie

gory Sands

e well as The Chemical Engineering Special Fowler. She was praised for her work Service Awards were given to GSC dedication to the department and hard experience. president Jason Kralj from Houston, work in the Graduate Student Office.

Photo: Gr TX, and current AICHE president, The Robert Princess Imoukhuede from Matteson, Phi Cup is a charity ice hockey event T. Haslam IL. Reuben Domike from Brookline, hosted by Alpha Epsilon Phi sorority. Cup was MA and Roger Aronow from San The Chemical Engineering Graduate awarded by Francisco, CA were also recognized Students were the Phi Cup champions Prof. Arm- for their hard work organizing the this year and were recognized with a strong ChemE Intramural athletic teams. plaque from the department. (Above L) to Hiroki Kaido (Above R). He is a senior from Greensburg, The Chemical Engineering “Rock” We would also like to congratulate

PA and was recognized for outstand- Award for Photo: Gregory Sands seniors, Princess Imoukhuede for ing professional promise in Chemical outstanding receiving the Betsy Schumacker Engineering. athletics, Award, Yolanda Fan for receiving as voted by the Frederick Gardinar Fassett, Jr. The Roger de Friez Hunneman ChemE grad- Award and Huanne T. Thomas for Prize is the oldest in the department uate students winning a Ronald E. McNair and is given to an undergraduate for went to Reuben Scholarship. They were acknowl- outstanding scholarship and research. Domike (R) for edged for these awards at the 2002 This year the award went to K. Jaisel active participa- MIT Awards Convocation, held on Vadgama from Calgary, Alberta. tion in Intra- Monday, May 13th.••• mural sports. The Edward W. Merrill Outstanding Jason Kralj (L), Teaching Assistant Award was presented the presented to Kimberly Bryan-Kosto, a award.

4 Faculty Appointments & Promotions IN THE DEPARTMENT OF CHEMICAL ENGINEERING •••

Alice P. Gast Welcomed to Faculty PhD from Princeton. Her research Promotions in the Department explores the frontiers of the chemical Photo: Stu Rosner Photo: Stu Rosner physics of colloidal and polymer Linda G. solutions, polymer adsorption and Griffith, most recently proteins. promoted to Full Professor, Gast was a notably effective teacher at joined MIT as Stanford and is the co-author a postdoc in of a classic textbook on colloid and 1988, follow- surface phenomena. Her numerous ing her grad- honors include a Camille and Henry uate work at Dreyfus Teacher Scholar Award and U.C. Berke- Professor Alice P. Gast Professor the Allan P. Colburn Award. She was Linda G. Griffith ley. In 1990, elected to the National Academy of she was n September 2001, the Department Engineering in the Spring of 2001. appointed Asst. Prof., and in 1996 welcomed new Robert T. Haslam was promoted to Assoc. Prof. She is IProfessor, and MIT Vice a tissue engineering pioneer and has President for Research and developed a range of new biomaterials Associate Provost, Alice P. Gast. “We are extremely delighted to and approaches to constructing have Alice join the department. functional 3-D tissues for therapeutic “Alice is a renowned researcher, She is one of the world’s leading and clinical diagnostic use. Her scholar and educator and a experts in complex fluids and accomplishments have resulted in tremendous advocate for research,” colloids, and one of the world’s numerous awards, editorial said Provost Robert A. Brown in leading and most exciting appointments, and speaking invita- announcing the appointment, “She chemical engineers.” tions. (Also see article, page 6)••• adds a wonderful perspective to the leadership of MIT.” Prof. Robert C. Armstrong Paula T. Photo: Stu Rosner Head, MIT Chemical Engineering Hammond, Gast coordinates policy regarding promoted to research and graduate education and Associate oversees the Institute’s large Prof. with interschool laboratories. She works “It wasn’t easy for me to leave Tenure, has with Brown in coordinating these Stanford and all my wonderful been on the areas through the budgeting process colleagues and students,” she said. Chemical Professor and through the planning, assignment “I had the best of times there and Engineering Paula T. Hammond and utilization of space at the hope I’ve left a positive imprint on Faculty Institute, also reporting to Chancellor those I have taught and worked with. since 1994. Prof. Hammond’s PhD Phillip L. Clay, on matters of My career benefited greatly from the (’93) and SB (’84) are both from MIT. graduate education policy. tremendous support of my department She received her MS from Georgia and school. I look forward to building Tech, and in 1994 completed “Alice Gast has the ideal background, the same collegial relationships at Postdoctoral work at Harvard interests and skills to foster MIT.” University. interdisciplinary research at MIT,” said President Charles M. Vest. “Her Gast was the valedictorian of the Hammond’s research centers on the own work has been at the interface of Class of 1980 at the University of newest frontier in polymer science, science and engineering, and she has Southern California when she self-assembly: the inherent tendency thought deeply about how to create received the BS in chemical of some materials to self-arrange due supportive environments and facilities engineering. She went on to earn an to thermodynamic driving forces and for faculty who want to pursue MA (1981) and PhD (1984) from non-covalent secondary interactions. research and education that cross Princeton. She is a member of She has received a number of com- traditional boundaries. I very much the American Association for the mendations for her work including the look forward to working with her.” Advancement of Science, the 2000 Junior Bose Faculty Award, American Chemical Society, the 1997 NSF Early Career Award, Gast joined us from Stanford in Fall American Institute of Chemical 1996 EPA Early Career Award 2001, where she had been on the Engineers and the American Physical the 1996 duPont Young Faculty faculty since 1985 after earning the Society.••• Award.(Also see article, page 16)•••

5 Cooney Named Faculty Director for New Innovation Center

he marriage of technical Photo: L. Barry Hetherington creativity to business acumen Thas become a growing feature “The establishment of the Deshpande Center of MIT’s reputation as a hot bed for Technological Innovation is an exciting for budding technology entrepreneurs. opportunity for MIT, as it will allow us Despite this vitality, a need exists to fund cutting-edge research at an early to more successfully join potential stage and accelerate emerging technology entrepreneurs --particularly for development towards real-world impact.” research in the incipent stages--with capital. As recently appointed Professor Charles L. Cooney, Faculty Director Faculty Director of MIT’s new Deshpande Center for Technological Innovation Deshpande Center for Technological Innovation, MIT ChemE Prof. Charles L. Cooney may now be in a position to help smooth the road to funding for budding MIT innovators. but still-incipient technologies. The Since 1991, Prof. Charles L. Cooney Center also helps fund the new has been co-director of the Program With a generous $20M gift from Undergraduate Practice on the Pharmaceutical Industry, Jaishree and Desh Deshpande, Opportunities Program (UPOP), which cuts across the Schools of co-founder and Chairman of which places MIT undergrads in Science, Engineering, and Sycamore Networks, Inc., the new industry and government internships. Management. He was MIT ChemE’s Center was established in January Executive Officer (1996-2001), and 2001 to serve as a catalyst for Dr. Deshpande remarked, “MIT has currently is on sabbatical leave at the innovation and entrepreneurship by always provided a fertile ground University of Cambridge. He received supporting research and collaboration where its students and faculty can the BS in Chemical Engineering from among entrepreneurs, young break down through technology the U. Penn.in 1966, and the SM companies, and MIT students, alumni barriers, fuel new areas of research (’67) and PhD (’70) in Biochemical and faculty. Initial opportunities for and development, and fundamentally Engineering from MIT. He joined support will include three MIT faculty transform whole industries. We can the MIT Faculty as Asst. Professor grants for “ground breaking” research think of no better place to begin this in 1970, was promoted to Assoc. at $250K each, and five $50K grants work.” Professor in 1975, and to Full to support research into exciting, Professor in 1982.••• Klavs Jensen Elected to NAE Griffith, Langer Focus of PBS Program Photo: Stu Rosner Election to the National Academy of Engineering is one of the highest Prof. Linda professional distinctions that can G. Griffith be accorded an engineer. Academy (L) explains membership honors those who have her “Liver made “important contributions to Chip” engineering theory and practice” and (BELOW) those who have demonstrated to Alan Alda “unusual accomplishment in the (R), host of Prof. Klavs F. Jensen pioneering of new and developing “Scientific American Frontiers.” The fields of technology.” Chip allows living human liver cells ongratulations to Klavs F. to serve as test Jensen, Lammot du Pont Also recently elected were Professor subjects. Alda CProfessor of Chemical featured both Douglas A. Lauffenburger (See Engineering, who was recently elected article, page 21) and two MIT ChemE Griffith’s andProf. to the National Academy of alumni Rakesh Agrawal (ScD ’80) Robert Langer’s Engineering. Jensen was elected and Frank Bates (ScD ’82).••• work in his program in recognition of his “fundamental “Body Building” contributions to multi-scale chemical For more information about Prof. which aired in May 2002. Videos and reaction engineering with important Klavs F. Jensen... more at the web sites below: applications in microelectronic http://web.mit.edu/cheme/people/faculty/ http://www.pbs.org/saf/1209/segments/ materials processing and microreactor jensen.html 1209-2.htm (GRIFFITH) technology.” This is an outstanding http://www.pbs.org/saf/1209/segments/ honor for Prof. Jensen and richly 1209-1.htm (LANGER) deserved.

6 Langer Wins “Triple Crown” for Biomedical Innovations

For more about the Draper Prize.. Langer’s Inspiration for Innovation http://www.nae.edu/nae/naehome.nsf/ weblinks/NAEW-4NHML8?Opendocument In 1974, with a new MIT PhD in chemical engineering, Robert Langer declined the lucrative Othmer Gold Medal industrial job offers pouring in. Instead, he went to The 2002 Othmer Gold Medal was work in the lab of famous cancer researcher Judah awarded to Langer in a gala event at Folkman at Children’s Hospital in Boston. “This job had a profound impact on what I ended up doing with the Chemical Heritage Foundation my life,” says Langer. “One of the great things about (CHF)’s June Othmer Award Photo: L. Barry Hetherington Dr. Folkman was that he believed almost anything was Luncheon held in CHF’s new possible, and seeing his example was terrific for me.” Philadelphia headquarters. Langer’s address to the prestigious gathering, explored biomaterials, and how they will change people’s lives. He highlighted the critical emerging roles pecial recognition goes to nevertheless discovered engineering that chemists and chemical engineers Robert S. Langer, Kenneth principles that would allow a desired will play in the advancement of life SJ. Germeshausen Professor of release of these molecules from sciences, particularly with the spread Chemical and Biomedical plastic devices. of pathbreaking technologies such as Engineering. For 2002, Langer tissue engineering and drug delivery. garnered three of the most Langer’s creative engineering of distinguished honors in the field: polymer plastics is now allowing Established in 1997, the annually- the Charles Stark Draper Prize, delivery of medicine in unique ways awarded Othmer Gold Medal honors given by the National Academy of to difficult locations in the body. outstanding individuals who have, Engineering, the Chemical Heritage One of his biodegradable polymer like Donald Othmer (1904-95), made Foundation’s Donald Othmer Gold inventions broke a 20-year drought multifaceted contributions to our Medal, and the American Institute in FDA-approved brain cancer chemical and scientific heritage of Chemical Engineers (AIChE) treatments-- the first such through outstanding innovation, Institute Lecturership. chemotherapy that could be delivered entrepreneurship, research, education, directly to a tumor site. legislation or philanthropy. Charles Stark Draper Prize Langer was honored with the Charles That success is just one of many For more about the CHF Othmer Stark Draper Prize for his invention for Langer, who is among only Gold Medal.. of medical technologies that help a handful of active members of http://www.chemheritage.org prolong lives and ease suffering. He all three U.S. National Academies- is a pioneer in applying engineering -National Academy of Sciences, principles to medical problems, and National Academy of Engineering, AIChE Institute Lectureship his groundbreaking discoveries are and Institute of Medicine. He has The Institute Lecturer Award is given a cornerstone of the controlled written about 700 papers and holds annually in recognition of “the quality drug-delivery industry, which is a some 400 patents licensed or and relevance of the accomplishments $20 billion enterprise in the US sub-licensed to around 80 companies, of the lecturer,...the communication alone. The Draper Prize, often called some launched using his ideas. He skills of the lecturer, and the value of engineering’s Nobel, is awarded has a reputation for helping students the lecture to the meeting attendees annually and consists of $500,000 and take their theses to the marketplace. and the members of the Institute.” a gold medallion. Langer is proud of the students he has shepherded into professorships,more Langer’s lecture, “Biomaterials in “Bob Langer was chosen both for than 80 at universities worldwide, Drug Delivery and Tissue the substance of his contributions and and the subsequent impact on Engineering” was presented on because he is a role model,” says NAE advancing chemical engineeering and November 6th at the 2002 AIChE President Wm. A. Wulf. “The large bioengineering education. Annual Meeting in Indianapolis, number of companies his students Indiana.••• have created is notable, effectively The NAE established the Draper transferring the technology he has Prize, with an $8-M endowment from For more about Prof. Langer... created into the private sector where it the Charles Stark Draper http://web.mit.edu/cheme/people/faculty/ becomes available to all of us.” Laboratory, to honor the “father of langer.html inertial navigation.” It is awarded for It had been thought that large innovative engineering achievement molecules, including some promising or a body of work extending over anti-cancer agents, could not pass a period of years. The work must through plastic delivery systems in demonstrate a proven innovation that a controlled manner. Langer contributes to human welfare and freedom. 7 Faculty Distinctions

IN THE DEPARTMENT OF CHEMICAL ENGINEERING •••

Professor Robert C. Armstrong Non-Aqueous Media” at the Sympo- Professor Brown continued to serve continued as Head of the Department sium. He was also guest editor of on the International Academic of Chemical Engineering during the the section on “Thermodynamics and Advisory Panel (IAAP) to the Gov- academic year 2001-2002. In Novem- Theoretical Aspects of Colloid Sci- ernment of Singapore and as Director ber 2001 he received the Distin- ence” for the journal, Current Opinion of the DuPont-MIT Alliance (DMA) guished Service Citation Award, in Colloid and Interface Science. He at MIT. He was a plenary speaker from the College of Engineering at the continues to serve in the editorial at the World Congress on Chemical University of Wisconsin-Madison. He boards of Current Opinion in Colloid Engineering in Melbourne, Australia was elected as Second Vice Chair of and Interface Science and Marcel in October 2001 and at the American the Governing Board of the Council Dekker’s Surfactant Science Series. Institute of Architects’ (AIA) Confer- for Chemical Research (CCR); he will Professor Blankschtein received the ence on Architecture and Education in Chair this organization in 2005. He 2002 Outstanding Faculty Award Boston, Massachusetts in April 2002. currently serves on the External Advi- from the graduate students in the Professor Brown also delivered the sory Boards and/or Visiting Commit- Department of Chemical Engineering, Lavoisier Lecture at E.I. DuPont de tees of the respective Departments of and continues to serve as Graduate Nemours and Company in 2001.••• Chemical Engineering at the Georgia Officer in the Department.••• Institute of Technology, Northwestern Professor Robert E. Cohen contin- and Texas A&M Universities, the Uni- Professor Howard Brenner received ued as Chair of the Steering Com- versities of Michigan at Ann Arbor the 2001 Fluid Dynamics Prize of mittee of the PhD in Chemical and of Wisconsin at Madison, and the the Division of Fluid Dynamics of the Engineering Practice (PhDCEP) Virginia Polytechnic Institute.••• American Physical Society (APS). He doctoral program, now in its third served as a member of the Chemical year of operation. Eleven students are Professor Paul I. Barton gave Engineering Peer Review Committee currently enrolled in various stages invited papers at the Fifth Society for of the National Academy of Engineer- of the Program. He also continues Industrial and Applied Mathematics ing (NAE), and was chosen to serve to co-direct, with Professor Douglas (SIAM) Conference on Control and for the period 2002-2005 as a member Lauffenburger, the operations of the its Applications in San Diego, Califor- of the Membership Committee of DuPont-MIT Alliance (DMA), a $35 nia; the International Conference on that organization. During the year, million/5-year education and research Scientific Computation and Differen- he presented or co-presented invited initiative in the area of bio-based tial Equations in Vancouver, British seminars and lectures at the State materials. (See article, page 22) Columbia, Canada; the Sensitivity University of New York at Buffalo Professor Cohen is a member of the Analysis Workshop 2001 at the (SUNY-Buffalo), the Annual Meeting External Advisory Committee of the Lawrence Livermore National Labo- of the Division of Fluid Dynamic Department of Chemical Engineering ratory in California; and the Seventh of the American Physical Society at Columbia University. He continues SIAM Conference on Optimization in (APS), including delivering the Fluid to serve as a member of the Board Toronto, Ontario, Canada. He gave Dynamics Prize lecture, the Annual of Directors of the William and Mary an invited lecture at Lehigh Uni- American Institute of Chemical Engi- Greve Foundation in New York. He versity in Bethlehem, Pennsylvania. neers (AIChE) Meeting, the Society is also a Director of Mattek Corpo- He was elected a Director of the of Rheology, the University of Florida ration, a surface science/tissue engi- American Institute of Chemical Engi- Engineering Research Center for Par- neering company he co-founded in neers (AIChE) Computing and Sys- ticle Science and Technology, the 1985 with former colleague, Professor tems Technology (CAST) Division, Division of Engineering and Applied Emeritus Raymond F. Baddour. Pro- continued to serve on the editorial Science (DEAS) at Harvard Univer- fessor Cohen’s 12-student research board of Chemical Engineering and sity, and the International Workshop group generates new knowledge, pub- Processing, and organized a mini on Particles and Polymers Near lications and patents in the area of symposium at the International Con- Interfaces in the Netherlands.••• polymer science and technology. In ference on Scientific Computation and the past year papers were presented Differential Equations in Vancouver, Professor Robert A. Brown at the meetings of the American Insti- British Columbia, Canada.••• continued serving as Provost at MIT, tute of Chemical Engineers (AIChE), a position he has held since 1998. American Chemical Society (ACS), Professor E. Daniel Blankschtein He also continued as executive editor and the Materials Research Society was a Keynote Speaker at the of the Journal of Chemical Engineer- (MRS), and invited lectures were 76th American Chemical Society Col- ing Science and as a member of delivered at the University of Min- loid and Surface Science Symposium the National Research Council (NRC) nesota, the University of Massa- in Ann Arbor, Michigan and also decadal study on the “Frontiers in Chaired a session on “Nanoscale Chemistry and Chemical Engineer- Organization via Self-Assembly in ing.” Among other forms of service, DISTINCTIONS see facing page 8 DISTINCTIONS from facing page Professor Patrick S. Doyle was an Eidgenössische Technische Hoch- invited lecturer at the University of schule (ETH) in Zürich, Switzerland, chusetts, and Columbia University. Massachusetts at Amherst, Brandeis Stanford University, the Pennsylvania Professor Cohen’s teaching responsi- University, General Electric, and the State University, the University of bilities include 10.568, Polymer Phys- Massachusetts General Hospital. Pro- Arizona, the Georgia Institute of ical Chemistry, a popular graduate fessor Doyle’s group continues to Technology, Intel Corporation, and elective in chemical engineering and investigate single molecule DNA the DuPont Corporation. Together required core subject in the curricu- dynamics and to develop mesoscopic with two of her former PhD students, lum of the interdepartmental Program simulations for studying polymer rhe- Professor Gleason co-founded GVD in Polymer Science and Technology ology. On the MIT campus, he devel- Corporation, the aim of which is to (PPST). He developed and delivered oped a new Independent Activities translate her laboratory’s inventions a new module for the undergraduate Program (IAP) course for freshmen for the vapor deposition of polymeric subject, 10.491, Integrated Chemical entitled “Hands-on ChE” with coatings to commercial applications in Engineering (ICE). The new ICE Professor Kenneth Beers.••• the membrane, medical device, and module introduced students to con- biopharmaceutical sectors.••• cepts of product design and structure/ Professor Alice P. Gast, Vice property relationships in the context President for Research and Associate Professor William H. Green, Jr. of polymeric gas separation Provost, joined the MIT faculty and joined the Editorial Advisory Board of membranes.••• administration in November 2001. the International Journal of Chemical (See article, page 5) She has remained Kinetics in January 2002. Professor Professor Charles L. Cooney the Co-Chair of the National Research Green continues to Co-Chair the ses- stepped down from the position Council (NRC) Board on Chemical sions on “Combustion Reaction Engi- of Executive Officer of the Depart- Science and Technology and on the neering” for the American Institute of ment on June 30, 2001 and after fin- visiting committee for the Cornell Chemical Engineers’ (AIChE) annual ishing coordination of the American University School of Chemical Engi- meeting. He presented invited lectures Board of Engineering and Technology neering. Last fall she gave the Holtz on his research to the Chemical (ABET) review for the Department in Lectures at the Johns Hopkins Engineering Departments at Stanford September 2001 left for a yearlong University and was inducted into University and the University of Cali- sabbatical at the University of Cam- the National Academy of Engineering fornia at Santa Barbara, and at the bridge in the United Kingdom in (NAE). She gave the Henske Lecture American Chemical Society’s (ACS) the Chemical Engineering Depart- at Yale University and the plenary Spring National Meeting. Professor ment. He continues on the Board of lecture at the 76th American Chemi- Green wrote an overview of his work the MIT Community Services Fund. cal Society (ACS) Colloid and Sur- on computing rate constants from first He is the Co-Director of the Consor- face Science Symposium in Ann principles for Theoretical Chemistry tium for Advanced Manufacturing of Arbor, Michigan. She was awarded Accounts. On a more practical side, Pharmaceuticals (CAMP), an industry the University of Southern Califor- he invented a method for establishing consortium jointly run with Purdue nia (USC) School of Engineering the fundamental limits on achievable University to support research on Award for Academic Excellence. yields in complex catalytic processes, pharmaceutical manufacturing and She has moved her laboratory and and a method for predicting the range continues as Co-Director of the Pro- one student to MIT, graduated two of operability of novel homogeneous gram on the Pharmaceutical Industry students and has four remaining at charge compression ignition (HCCI) (POPI), a joint program between Stanford University. Her National internal combustion engines. Profes- the Schools of Engineering, Science, Aeronautics and Space Administra- sor Green and Professor Herbert H. Humanities and Management at MIT. tion (NASA)-sponsored research on Sawin developed and co-taught the On March 1, 2002, Professor Cooney magnetic fluids will be moved to the new subject, 10.10, Introduction to was appointed as Faculty Director of International Space Station; her first Chemical Engineering, for freshmen the new Deshpande Center for Tech- experiment will be performed there in the spring 2002 term. It is antici- nological Innovation in the School this fall.••• pated that this will become the first of Engineering. (See article, page 6) required subject for chemical He has continued his participation on Professor Karen K. Gleason engineering majors.••• the external review committee for the completed her first year as the Depart- Department of Chemical Engineering ment’s Executive Officer. In this Professor Linda G. Griffith was of the University of Cambridge and role, she won Institute approval for promoted to Full Professor of chemi- was named as a Cambridge-MIT Insti- required changes to the undergraduate cal and biological engineering effec- tute (CMI) Fellow in March 2002.••• curriculum that enhanced the intro- tive July 1, 2002. She is continuing ductory and capstone experiences for to develop the LiverChip™ for study Professor William M. Deen and the undergraduate chemical engineering of liver physiology and detection of members of his laboratory continued majors. Professor Gleason also led biowarfare agents and environmental their investigations in the areas of a Department-wide curriculum review toxins. Her work was profiled in May hindered transport in fibrous media, process this spring aimed at on the PBS series “Scientific Ameri- water and macromolecule filtration in promoting more rapid introduction of can Frontiers” hosted by Alan Alda. kidney capillaries, and physico-chem- examples from biology and advanced (See article, page 6) She is partici- ical aspects of nitric oxide toxicity materials into the core undergraduate pating in the Cambridge-MIT Institute and carcinogenicity.••• subjects. In addition, she gave invited presentations at Semicon Japan, the DISTINCTIONS see page 10

9 DISTINCTIONS from page 9 deposition, and quantum dot compos- Best”) and one of the 18 Most Impor- ite materials for optical devices. The tant Individuals in Science and Med- (CMI) program and was chosen as a MicroChemical Systems Technology icine in the United States. Discover CMI fellow.••• Center was started in his laboratory Magazine also named him one of “20 with support of eight international Biotech Geniuses to Watch.”••• Professor Paula T. Hammond was chemical and pharmaceutical com- promoted this year to Associate Pro- panies. Jensen was also principal Professor Paul E. Laibinis delivered fessor with tenure in the Department investigator for the new MIT Mul- invited seminars at Rice University, of Chemical Engineering effective tidisciplinary University Research Rensselaer Polytechnic Institute July 1, 2002. Professor Hammond’s Initiative (MURI) program on micro- (RPI), the Johns Hopkins University, research work on directed assembly chemical systems for conversion of the Massachusetts General Hospital, of colloidal particles on patterned sur- fuel to electrical power. This program Notre Dame, Texas A&M, and North faces was featured on the cover of involves researchers from a number Carolina State Universities, the Advanced Materials; the image, which of departments across the School Universities of Houston and of Maine, was captured by Felice Frankel, was of Engineering. He participated with Tufts and Columbia Universities, the also featured in a photography text colleagues from the Departments of City College of New York, and var- by Dr. Frankel just released by the Biology, Chemical Engineering, and ious industrial laboratories. He gave MIT press. Professor Hammond was Electrical Engineering and Computer invited presentations at the 2nd Chem- a key faculty member responsible for Science in a DuPont-MIT Alliance ical Engineering Conference for the identification, planning and writ- (DMA) research project on microfab- Collaborative Research in the Eastern ing of a proposal for the Institute ricated bioprocessors. He co-chaired Mediterranean in Turkey, an interna- for Soldier Nanotechnologies (ISN) the National Research Council (NRC) tional conference on “Self-Assembly: at MIT. This major multidisciplinary Workshop on Materials and Processes The Future” in Italy, and various research center, involving over 35 as a part of the NRC’s survey of domestic meetings on his group’s MIT faculty members, was funded chemical sciences. As the 2002 L.K. development of a new class of chemi- for $50 million by the United States Doraiswamy Lecturer he presented cal sensors and gene chips. For his Army, is directed towards new tech- lectures at the Iowa State University efforts in surface engineering, he was nologies for the protection of the sol- and the Indian National Chemical selected by the Information dier. (See article, page 16) Professor Laboratory in Pune, India. He also Sciences Institute (ISI) in 2002 as Hammond is a member of the ISN gave the 2002 Donald L. Katz Lec- being among the top-cited authors in Executive Committee, is the Facilities tures at the University of Michigan at the area of molecular self-assembly Coordinator and is a Research Team Ann Arbor and several invited presen- during 1981-1999. He serves on the Leader in the ISN. She has given tations on microchemical systems at editorial boards of the journals Lang- invited talks at the Gordon Confer- national and international conferences muir and Sensors and the Victor K. ence on Polymers in Ventura, Cali- and at universities.••• LaMer Award Committee of the fornia and the Polyelectrolytes 2002 Colloid and Surface Chemistry Divi- Conference in Lund, Sweden. She was Professor Robert S. Langer was sion of the American Chemical Soci- also an invited speaker at several com- honored by the National Academy ety (ACS). Professor Laibinis is also panies and universities, including the of Engineers (NAE) with the 2002 a faculty fellow in the Singapore- University of Minnesota, the Georgia Charles Stark Draper Prize, the MIT Alliance (SMA) Program on Institute of Technology, and world’s most prestigious engineering the Molecular Engineering of Schlumberger.••• prize, which carries an award of Biological and Chemical Systems. In $500,000.00. (See article, page 7) January 2003, Prof. Laibinis will join Professor Jack B. Howard continues Also, he received an honorary doc- the Chemical Engineering Department to serve as Director of the Center torate from the Hebrew University of at Rice University.••• on Airborne Organics involving MIT, Jerusalem in Israel in 2002. He was the California Institute of Technology, awarded the Othmer Gold Medal Professor Douglas A. Lauffenburger and the New Jersey Institute of Tech- from the Chemical Heritage Founda- was elected this past year to mem- nology. He was the Paul Chung tion and the 2002 Nagai Innovation bership in the National Academy of Distinguished Lecturer in the College Award from the Controlled Release Engineering (NAE) and the Amer- of Engineering at the University of Society. He was the 2002 Distin- ican Academy of Arts & Sciences Illinois at Chicago and he received the guished Lecturer at the University of (AAA&S). (See article, page 21) At honorary doctor of engineering from Louisville, the 2002 Institute Lecturer MIT, he continues as Co-Director of the Colorado School of Mines.••• of the American Institute of Chemical the Biological Engineering Division Engineers (AIChE), the 2001 Ullyot (BE), formerly the Division of Bioen- Professor Klavs F. Jensen was Lecturer of the Chemical Heritage gineering and Environmental Health elected to the National Academy of Foundation, the 2001 Clapp Lecturer (BEH), Director of the Biotechnology Engineering (NAE). (See article, at Brown University, the 2001 Julian Process Engineering Center (BPEC), page 6) In collaboration with col- Smith Lecturer at Cornell University, and Associate Director of the DuPont- leagues at MIT, he continued research the 2001 Mason Lecturer at Stanford MIT Alliance (DMA) in bio-based on microfabricated chemical systems University, and the 2001 Distin- materials. Nationally he serves on the for chemical and biological synthesis guished Lecturer at Carnegie Mellon Advisory Council for the National and analysis, microsystems for fuel University. Time Magazine named Institute of General Medical Sciences, processing, on multiscale modeling him one of the “100 Most Important of reactive processes for thin film People in America” (“America’s DISTINCTIONS see facing page

10 DISTINCTIONS from facing page Plasma Symposium on the use of Spain, the Bioinformatics Gordon multivariate statistics for the analysis Research Conference in, and the and this year is the Chair of the of optical emission in the identifica- Princeton Symposium on Metabolic College of Fellows of the American tion of endpoint in plasma etching Engineering. In 2002 he presented at Institute of Medical and Biological processes. He gave a chemical engi- the Conference on New Biology at Engineering (AIMBE).••• neering departmental seminar at the the University of Illinois at Urbana- University of California/Los Champaign, the European Sympo- Professor Gregory C. Rutledge is Angeles.••• sium on Biocatalysis in Italy, and currently serving as Director of the the Annual DECHEMA (the German Program in Polymer Science and Professor Kenneth A. Smith has Association of Industrial Chemists) Technology (PPST) at MIT, an inter- continued his research on the roles Meeting in Wiesbaden, Germany. He disciplinary educational program that of fluid mechanics and transport phe- was also the 2002 Merck Lecturer at draws a small but élite group of grad- nomena in a number of contexts. the University of Virginia and at the uate students to MIT for polymer These include use of the supercritical Rutgers University Distinguished studies. He has continued his research water oxidation process for destruc- Lecture series. Professor Stepha- to develop improved tools for the tion of organic wastes, jointly with nopoulos also participates in the atomistic modeling of polymeric Professor Jefferson W. Tester, and the DuPont-MIT Alliance (DMA), is a materials and on electrospinning of dynamics of micellar self-assembly, Fellow of the Singapore-MIT polymer nanofibers. He is a team jointly with Professor T. Alan Hatton. Alliance (SMA) and a member of the leader for Processing and Charac- He is also engaged in the development International Faculty of the Technical terization in the new Institute for of an instrument that can determine University of Denmark.••• Soldier Nanotechnologies (ISN) at the size-segregated chemical composi- MIT, as well as a continuing inves- tion of an aerosol in real time. He is Professor Jefferson W. Tester, after tigator in the Center for Materials participating in the Molecular Engi- serving as the Director of the Energy Science and Engineering (CMSE), neering of Biological and Chemical Laboratory for the past 12 years, the Center for Advanced Engineer- Systems (MEBCS) program within decided to step down and resume his ing Fibers and Films (CAEFF), the the Singapore-MIT Alliance (SMA). responsibilities as a faculty member National Textile Center, and the Air In addition, he delivered invited in the Department. He continues to Force Program on Nanocomposites lectures at Tsinghua University in be active in the energy area where at MIT. Over the past year he has Beijing, China and at the Eidgenös- he remains as Chair of the National delivered a number of invited talks, sische Technische Hochschule (ETH) Advisory Council of the Department including those at the European Poly- in Zürich, Switzerland.••• of Energy’s (DoE) National Renew- mer Society, the Centre Européen able Energy Laboratory (NREL) and de Calcul Atomique et Moléculaire The central goal of Professor Greg- Co-Chair of the Governor’s Advisory (CECAM) – the European Center ory Stephanopoulos’s educational Board for the Massachusetts Renew- for Atomic and Molecular Com- and research activity is to extend the able Energy Trust. Professor Tester putations – at the École Normale chemical engineering paradigm to the also continued as a member of the Supérieure in Lyon, France, the Amer- analysis and design of biological sys- advisory groups for the Paul Scherrer ican Society of Mechanical Engineers tems, thus developing a foundation for Institute, which is part of the Eid- (ASME), Gordon Research Confer- chemical and biological engineering genössische Technische Hochschule ence on Composites, the Flory Award at MIT and nationally. This requires (ETH/Swiss Federal Institute of Tech- Symposium of the American Chemi- increasing biological content in the nology) in Zürich, Switzerland and cal Society (ACS), the International chemical engineering curriculum and the Nuclear and Energy Systems Divi- Symposium on Polymer Crystalliza- tighter integration between biology sion of the Idaho National Engineer- tion in Mishima, Japan, and several and engineering. As Bayer Professor ing and Environmental Laboratory academic institutions. He continues to of the Department, his efforts were (INEEL). Last year, while he was serve on the editorial boards of Poly- recognized in the fall of 2001 by the on sabbatical he gave invited lectures mer and Computational and Theoreti- AIChE Wilhelm Award in chemical at Rensselaer Polytechnic Institute cal Polymer Science, and co-teaches reaction engineering, the 2002 Merck (RPI), the National Renewable Energy the ACS short course on Molecular Award in metabolic engineering and Laboratory (NREL), Los Alamos Modeling of Polymers.••• the 2002 CIO Magazine 20/20 Vision National Laboratory, the Conference Award honoring 20 academic (and on World Affairs at the University of Professor Herbert H. Sawin devel- 20 industrial), visionary leaders in Colorado, and provided invited oped, in collaboration with Professor information technology for pioneering testimony at several U.S. government William H. Green, Jr., a new intro- work in biological data mining and hearings and forums on distributed ductory course for the chemical bioinformatics. energy and renewable energy and on engineering curriculum, 10.10, Intro- sustainable waste treatment. He was duction to Chemical Engineering. Professor Stephanopoulos continued a recipient of the Department’s 2001 This course combines instruction in as co-editor of the journal, Metabolic Outstanding Faculty Award.••• mass and energy balances, engineer- Engineering, published by Elsevier ing problem solving, and MATLAB Academic Press and serves on the Professor Bernhardt L. Trout was programming. Professor Sawin was editorial boards of 7 other scientific named the Henry C. and Grace made a fellow of the American journals. In 2001 he delivered plenary Doherty Professor of Ocean Uti- Vacuum Society. He gave an invited lectures at the 10th European Con- talk at the Electrochemical Society ference in Biotechnology in Madrid, DISTINCTIONS see page 12

11 DISTINCTIONS from page 11 Conference on Nanostructured Mate- 168, but we are encouraged by a rials, and on the organizing committee roughly 25% increase in size of lization for his work on clathrate- of the Second Japan-America this year’s sophomore class relative hydrates. He was awarded an NSF Frontiers of Engineering Symposium. to last year’s. Similarly, during the CAREER grant for his work with Ying was the inaugural G.-J. Su academic year just ended, we granted solid-acid zeolyte catalysis. In Distinguished Lecturer at the Uni- 40 master’s degrees in Chemical addition, he has been granted a Ford versity of Rochester and an invited Engineering (with 29 of those in the Motor Company Young Investigator seminar speaker at the University of Practice School) and 32 doctorates. Award. He has given invited talks at California/Los Angeles (UCLA). She the National University of serves on the editorial boards of seven This fall (2002) we admitted over 70 Singapore, the National Research journals/book series, and on the new graduate students to study in one Council of Canada, and the California advisory boards of the Leibniz-Institut or both of the Practice School and Institute of Technology, in addition to für Festkörper- und Werkstoffforsc- Doctoral Programs. The quality of the the American Institute of Chemical hung Dresden in Germany, the Uni- students is excellent, as measured by Engineers (AIChE) and the American versity of Queensland Nanomaterials the large number of applicants to our Chemical Society (ACS). Funding for Centre in Australia, and the National program, the high degree of selectivity his projects on chemical and process Research Council Steacie Institute for exercised in our admissions process, design via molecular understanding Molecular Sciences in Canada. Ying and our unusually high yield (percent- is provided by the National Science is an honorary professor of chemistry age of admitted students who accept Foundation (NSF), the Department of of China’s Jilin University, a Director our offer). We are grateful to Profes- Energy (DoE), the National Aero- of the American Institute of Chemical sor K. Dane Wittrup and the Graduate nautics and Space Administration Engineers’ (AIChE) Materials Engi- Admissions Committee for their hard (NASA), Amgen, Inc., and the Ford neering and Sciences Division, and an work in bringing in these outstanding Motor Company.••• Executive Committee Member of the students. American Chemical Society’s (ACS) Professor Daniel I.C. Wang was Colloid and Surface Chemistry Divi- An essential asset in our effort to the keynote lecturer at the Society sion. She Chairs the Singapore-MIT attract the very best students to our of Industrial Microbiology/American Alliance (SMA) Program on Molec- Department is the generous external Chemical Society (ACS) in November ular Engineering of Biological and support to the Practice School and 2001 at their annual meeting held Chemical Systems (MEBCS).••• our doctoral program by our alumni, in Long Beach, California. Professor through endowed and continuing Wang Chaired the National Science Other members of the faculty in the support of graduate fellowships. We Foundation’s (NSF) Workshop on the Department include Professors Ken- are truly indebted to you for your “Future of Biochemical Engineering.” neth J. Beers, Clark K. Colton, T. ongoing commitment and support. He was awarded the Taiwan Semi- Alan Hatton, Gregory J. McRae, Beyond its value as a recruiting tool, conductor Corporation Professor Lec- George Stephanopoulos, Preetinder funds for graduate fellowships are tureship and delivered two lectures S. Virk and K. Dane Wittrup, as well an essential element of our graduate at Tsing Hua University, Hsinchu, as senior lecturers, Dr. Barry S. educational philosophy. Taiwan in June 2002. He delivered the Johnston and Dr. C. Michael keynote lecture at the 7th Asian Bio- Mohr.••• By targeting fellowship support on chemical Engineering Conference at Practice School students and begin- ning doctoral students, we can have Taipei, Taiwan in July 2002. He HEAD from page 1 was invited by the Institute of Chem- these students begin their graduate ical and Engineering Sciences in program, led by Professor Robert program focused on the core subjects Singapore to be a member of the Sci- E. Cohen), which is offered jointly of chemical engineering. This not entific Advisory Board for a three- between the Department of Chemical only provides all students with year appointment. In addition, he was Engineering and MIT’s Sloan School in-depth study of fundamentals that invited to deliver an address at the 2nd of Management. This program is underlie whatever specialty they Meeting of the MIT Club of Germany targeted at producing leaders for the pursue in chemical engineering, but in Munich in November 2002. Lastly, molecularly based technology sectors also provides doctoral students the he was also invited to deliver the key- by combining in-depth education in important opportunity to learn more note address on “Trends in Biotech- manufacturing, research, and manage- about the breadth of research oppor- nology” to be held in Vienna, Austria ment. We are entering our third year tunities in the Department before in November 2002.••• of this program, and we look to its choosing a thesis topic. This model first graduates emerging in a little less for educating graduate-level chemical Professor Jackie Y. Ying delivered than two years from now. engineers goes hand-in-hand with the fourteen invited lectures at interna- picture of modern chemical engineer- tional conferences and national meet- With the academic year that ended in ing as the central engineering disci- ings during 2002, including plenary June of this year, we again produced a pline embraced by our Department. lectures at the Third Int’l Symposium large number of graduates at both the on Mesostructured Materials in Korea undergraduate and graduate degree In the past year, there have also and the Fourth World Congress on levels. We awarded 82 SB degrees in been several significant changes in Particle Technology in Australia. She Chemical Engineering, 54 to women the faculty to bring to your attention, served on the scientific/programming and 28 to men. Our undergraduate committee of the Sixth International enrollment has decreased to around HEAD see page 17

12 ChemE Connection THE YEAR IN REVIEW AT A GLANCE •••

he past year has seen some Photo: Gregory Sands exciting growth in our depart- Tment. Two of our faculty received promotions this year. Paula T. Hammond, was promoted to Associate Professor with Tenure. Linda G. Griffith, was promoted to Full Professor.

The Department welcomed one new faculty member- Robert T. Haslam Professor Alice P. Gast, who also serves as MIT’s new Vice President for Research and Associate Provost. Gast comes to us from Stanford. (See article, page 5)

Faculty News We are proud to report the continued honors bestowed upon our outstand- ing faculty. Robert S. Langer, Prof. C. Michael Mohr (C) with 1997 Graduates (L to R): Brad Ricketson, Germeshausen Professor of Chemical Frank Greer, Bethany Rogers, Julia Greer, and Caroline Keller. and Biomedical Engineering, received And if that wasn’t enough, Lauffen- Undergraduate Laboratory, which three major awards this year--the burger who wears several hats as was finished last Spring!(See article Draper Prize, the Othmer Gold Professor of Bioengineering and and photos, pages 20-21) Medal, and the AIChE Institute Lec- Chemical Engineering, Co-Director, turer Awards. This trio of awards Division of Bioengineering & Changing Faces represents hard won recognition for Environmental Health and Director of This year has seen a number Langer’s prominent contributions to the Biotechnology Process personnel changes among our staff. the fields of tissue engineering and Engineering Center, also won this drug delivery. (See article page 7) year’s AIChE William H. Walker In July, we welcomed Alina Haverty, Award for Excellence in Contribu- our new ChemE Headquarters The Department honors Professors tions to Engineering Literature. Receptionist and Assistant to Klavs F. Jensen, and Douglas A. Congratulations to all of our award Executive OfficerKaren K. Gleason. Lauffenburger, who this year were winning faculty members! Alina comes to us from Nuvera Fuel both elected to membership in the Cells where she was working as the National Academy of Engineering Student Awards Executive Assistant to the Vice (NAE). Election to the NAE is one We’re proud to announce that five President of Technology. Prior to that of the highest professional distinctions ChemE Seniors, Allison M. Johnson, she worked at Arthur D. Little, as an that be accorded an engineer! Sheng Li, Luke D. Tomyez, Kaitya Administrative Assistant to the J. Vadgama, and Sheryl H. Yu Villa Managing Director. The Department Jensen was elected in recognition were elected to the honorary Phi is grateful to Patricia A. Sampson, of his “fundamental contributions to Beta Kappa society. Membership is for her excellence and dedication in multi-scale chemical reaction engi- conferred in recognition of excellent that position, and we wish her well in neering with important applications in academic performance and a demon- her new position in MIT’s Electrical microelectronic materials processing strated commitment to the objectives Engineering and Computer and microreactor technology.” (See of a liberal education. Science (EECS) Department. article page 6) Department News Melissa Lowthers recently joined the Lauffenburger was elected in recog- This was a year of major renovations Administrative Services Organization nition of his pioneering contributions in building 66. This included the (ASO), filling the post vacated by to the application of engineering in refurbishment of the second floor Stephen J. Malley. We’re sad to note molecular and cell biology, a quantita- offices, to accommodate our large Steve’s departure from the ASO, but tive understanding of molecular and entering class for Fall 2002, and first sources indicate that he’s in a new cellular processes, and for his leader- floor lab space - both scheduled for position right around the corner in the ship in the bioengineering community. completion in August 2002, and of DMSE Student Services Office!••• (See article, page 21) course the jewel in the crown, our new

13 Named Lectures

IN THE DEPARTMENT OF CHEMICAL ENGINEERING •••

joined MIT Chemical Engineering application of computers in education from 1982 to 1989, achieving the and research. Polymeric materials rank of Full Professor. He returned to and polymer-based materials systems Switzerland to a position of Professor have gained a large share of the of Macromolecular Chemistry at structural and functional materials ETH-Zürich. He has held various market. Trends point to growing Visiting Professor positions at complexity and miniaturization based University of Arizona; Seoul National on multi-functional materials. With University; National University of the aid of computer-assisted modeling

Photo: L. Barry Hetherington Singapore, and Imperial College, and and simulations, his group develops has been Proféssor Associé at both polymers that fulfill these needs E.S.P.C.I. in Paris and Université collaborating with partners in the Prof. Ulrich W. Suter, ETH Zurich Louis Pasteur, Strasbourg France. Institute of Polymers, in the His group produces approximately 5 Department of Materials, ETHZ, and diplomas and 4 doctorates per year. in Swiss and International technical Warren K. Lewis Lecture Cumulatively, 87 doctoral students colleges, universities, and industrial and young post-docs have come research and development he 2002 Warren K. Lewis from his group. He has published laboratories. Lecture was presented on approximately 280 papers. TFriday May 10, 2002, by This lecture series is a tribute to Ulrich W. Suter, Professor of Professor Suter’s research interests Warren “Doc” Lewis, who is well Materials, ETH Zurich, in 66-110. are in Macromolecular chemistry known as one of the Chemical Suter spoke about, “Polymeric and physical chemistry of polymers, Engineering Department’s most Nanocomposites.” particularly structure-property revered members. Also established relationships; polymeric materials, in his honor by the AIChE is the Prof. Ulrich (Ueli) W. Suter received particularly the predictability of Warren K. Lewis Award, which his Dr. Sc. Techn. in Chemistry at properties; atomistic, molecular, and recognizes outstanding educators in ETH-Zürich, Switzerland in 1973. He materials modeling and the chemical engineering.•••

Frontiers of Biotechology Lecture He is a Fellow of the American Photo: David Tucker Association for the Advancement of his year’s Frontiers of Science and the New York Academy Biotechnology Lecture was of Science, a foreign fellow of the Tpresented by George M. Indian National Science Academy, Whitesides, Mallinckrodt Professor and an Honorary Fellow of the of Chemistry at Harvard Chemical Research Society of India. University, on Friday September 28, His present interests include materials 2001 in Wong Auditorium. The topic science, biophysics, complexity, of his lecture was “Microfabricated surface science, microfluidics, self- Tools for Biotechnology.” assembly, micro- and nanotechnology, and cell-surface biochemistry. Whitesides received his A.B. from Harvard and PhD from CalTech. Frontiers in Biotechnology was He was a member of the MIT established in 1999, to acknowledge faculty before joining the Department the enabling technologies which have of Chemistry at Harvard. He has sustained the growth of biotechnology received numerous awards including and life sciences, and to honor the ACS Award in Pure Chemistry, the achievements of distinguished Prof. George M. Whitesides the Arthur C. Cope Scholar Award scientists and engineers in the field. Harvard University and the Arthur C. Cope Award, The Department warmly thanks Dr. the National Medal of Science, the Noubar Afeyan ’87 whose generous Von Hippel Award and many others. donation made this visionary new He is a member of the American series possible!••• Academy of Arts and Sciences, the National Academy of Sciences, and the American Philosophical Society.

14 his expertise in financing new of the Massachusetts Governor’s initiatives. His innovations have Economic Development Council. He earned the Laguna Niguel 1991 was honored by the Anti-Defamation and 1994 Best of Biotech awards, League’s New England Region with Hall of Fame Award in 1997, the 1995 Torch of Liberty Award the Special Recognition for an for his leadership in human rights Individual Award, and in 1993, the and for promoting understanding SWAT Team Award. among people of diverse backgrounds. In 1997, Mr. Termeer

Photo: L. Barry Hetherington Mr. Termeer has been acknowledged received The Governor’s New by “Wall Street Transcript” for four American Appreciation Award for his consecutive years and during success as a foreign-born entrepreneur 1990-92, received the Transcript’s in America and in 1999, he was Gold Award. Termeer was named inducted as a Fellow into the Henri Termeer, Chair 1992 Entrepreneur of the Year by American Academy of Arts and Genzyme Corp Merrill Lynch and Ernst & Young, Sciences. Inc. and in 1995, Success Magazine Alan S. Michaels Lecture named him “Renegade of the Year.” Prior to joining Genzyme, Mr. Termeer held various management n Friday, April 26, 2002, Mr. Termeer serves as a board positions during 10 years at Baxter Henri Termeer, President member for biotechnology Travenol (now Baxter International). Oand CEO of Genzyme corporations, including Genzyme In 1973, Mr. Termeer earned an Corporation presented this year’s Transgenics Corporation; Abiomed MBA from the Darden School at the Alan S. Michaels Lecture in 4-370 Inc.; AutoImmune, Inc. and Diacrin, University of Virginia. on the subject of “Biotechnology and Inc. and serves on the Board of Industry.” Associates of the Whitehead Institute This Lectureship has been established and as Chairman of the Genetics as part of an endowment fund donated Termeer was appointed President Advisory Council of the Harvard in honor of Alan S. Michaels, of Genzyme Corporation in 1983, Medical School. a distinguished leader in Chief Executive Officer in 1985, bioengineering. The series provides a and Chairman in 1988. Under his Mr. Termeer actively serves as a forum for annual lectures dedicated to leadership, Genzyme has grown into a trustee for Darden Graduate School bringing distinguished engineers from world biotechnology leader. of Business Administration, trustee academia and industry to share their Mr. Termeer is renowned for his and vice-chairman of the Boston views on research and development in contributions to biotechnology and Museum of Science, a member medical and biological engineering.•••

Hoyt C. Hottel Lecture expanded to include the duties of CEO Photo: L. Barry Hetherington of ARCO Alaska, Inc., and Senior n November 30, 2001 in Vice President of Atlantic Richfield 66-110, the annual Hoyt C. Company. He accepted the above- OHottel Lecture was presented mentioned positions with Phillips in by Kevin O. Meyers, Executive the Spring of 2000 when ARCO Vice President, Alaska Production Alaska, Inc. was acquired by Phillips. and Operations, Phillips Petroleum Company, on “Oil and Gas Dr. Meyers earned undergraduate Development in Alaska: An degrees in chemistry and mathematics Evolving Story.” from Capital University in 1975 and holds a doctorate in chemical K.O. (Kevin) Meyers was elevated engineering from MIT. Dr. Meyers to his current position in 2001 after serves on the University of Alaska serving as Senior Vice President of Board of Regents and on the boards Dr. Kevin O. Meyers, Exec. V.P. Alaska production and operations and of directors of the Alaska Oil and Phillips Petroleum Company President and Chief Executive Officer Gas Association, the Anchorage (CEO) of Phillips Alaska, Inc. in Symphony Orchestra, the Nature decades, and to the foundation and 2000. Dr. Meyers joined ARCO Conservancy of Alaska, the direction of the Fuels Research Exploration and Production (E & P) Anchorage Museum Fondation and Laboratory. The Lectureship is Technology in Plano, Texas in 1980. Commonwealth North. intended to draw eminent scholars, He has held a number of positions in preferably in field of combustion ARCO’s E & P Operations in both The Hoyt C. Hottel Lectureship was and energy technology, to MIT for Texas and Alaska, including Senior established in early 1985 to recognize short periods of residency, in order Vice President of the Prudhoe Bay Professor Hottel’s contributions to the to stimulate future generations of business unit in 1996, and in 1998, intellectual climate of the Chemical students. The inaugural Hottel Lecture President of ARCO Alaska, Inc. Later Engineering Department, to the was presented in April 1985 by Prof. that year, his responsibilities were encouragement of students over six Hottel, himself.••• 15 New Nanotech Institute Places ChE Faculty in Forefront MIT’s New Army Sponsored Institute for Nanotechnology Soldier Stresses Basic Science and Project Integration

esearchers from our Graphic: ISN Department are poised to play Ra leading role in MIT’s new $50M partnership with the US Army, known as the Institute for Soldier Nanotechnologies (ISN).

The mission of the new ISN, announced in March 2002, is to create lightweight molecular materials to equip foot soldiers of the future with uniforms and gear that can heal them, shield them and protect them against chemical and biological warfare.

MIT won an Army competition for the five-year, $50M proposal to which industry will contribute an additional $40M in funds and equipment.

Newly appointed Robert T. Haslam “Our goal is to help greatly enhance researchers foresee? Although “we Professor, and MIT V.P. for Research the protection and survival of the hope to deliver some goodies early,” and Associate Provost Alice P. Gast, infantry soldier using nanoscience within the next five years, Thomas and ChemE Professor Paula T. and nanotechnology,” said Thomas, said, some are indeed futuristic and Hammond played leading roles in the Morris Cohen Professor of many years from reality. Provost planning the new Institute, with Materials Science and Engineering. Brown noted that “if you don’t have DMSE Prof. Edwin L. Thomas as a vision that pushes the science and ISN Director. “This will be achieved by creating, engineering for a giant leap, you can’t then scaling up to a commercial level, do anything.” “I applaud my colleagues who have revolutionary materials and devices worked long and hard to win this composed of particles or components The ISN will focus on six key soldier competition,” said Provost Robert A. [often] so tiny that hundreds could fit capabilities: threat detection, threat Brown. “This is an important on the period at the end of this neutralization (such as bullet-proof [milestone] in MIT’s history.” He sentence. The idea is to incorporate clothing), concealment, enhanced noted MIT’s history of responding to these nanomaterials and nanodevices human performance, real-time the needs of our nation’s military by into the future soldier’s uniform, and automated medical treatment, and rapidly developing technologies that associated equipage like helmets and reduced logistical footprint (i.e., save soldiers’ lives. gloves,” Thomas said. lightening the weight load of the fully equipped soldier). At the news The ISN involves 9 faculty from In addition to protecting the conference announcing ISN Thomas ChemE working in 6 different teams. individual soldier, “imagine the noted that one ISN goal is to reduce In addition to MIT faculty, graduate psychological impact upon a foe the weight of a soldier’s equipment students, and postdoctoral associates, when encountering squads of from today’s 125-145 pounds to the from several departments, the ISN seemingly invincible warriors 45 pounds carried by Roman warriors. will also include specialists from protected by armor and endowed with These themes in turn are addressed the Army, E.I. duPont de Nemours superhuman capabilities, such as the by seven research teams: energy and Co., Wilmington, Del.; Raytheon ability to leap over 20-foot walls,” absorbing materials, mechanically Co., Lexington, Mass.; and physicians said Thomas. The leaping ability, he active materials for devices and from Massachusetts General Hospital explained at the news conference, exoskeletons, detection and signature and Brigham and Women’s Hospital. would be enabled by “building up management, biomaterials and energy storage in shoes.” Thomas nanodevices for soldier medical These researchers will develop ideas went on to note that MIT researchers technology, process systems for such as a uniform that is nearly have recently created “world-record manufacture and processing of invisible, soft clothing that can actuator materials” that are “better materials, modeling and simulation, become a rigid cast when a soldier than human muscles.” and systems integration. In addition, breaks his or her leg, and paper- Raytheon, DuPont and Massachusetts weight chainmail made of molecular What is the time frame for the materials. revolutionary products ISN ISN see facing page 16 ISN from facing page activated to create an offensive by co-director Professor Robert A. “forearm karate glove.” Brown and by co-chairs of the General/Brigham and Women’s MIT Steering Committee Professors Hospital are Founding Industrial “Now yet again the U.S. faces threats Robert E. Cohen and Douglas A. Partners, who will work closely that challenge our country to Lauffenburger. (See article page 22) with the ISN and with the Army capitalize on the enabling power of Natick Soldier Center and the Army novel technologies. The ISN really Finally, our faculty continue to distin- Research Laboratory, Aberdeen, MD, embodies a great opportunity to create guish themselves, and the past year to advance the science in field-ready these new technologies to protect our has produced another extensive list products. soldiers,” said Thomas. of faculty honors and awards. To name just a few notable achievements, The researchers are confident that Lieutenant Colonel Brian L. Baker, Professor Robert S. Langer was these teams will build off each other commander of MIT’s Army ROTC awarded the 2002 Charles Stark to create products with a variety of program, noted that in the past, Draper Prize, the highest honor applications. For example, an technology has been used “to take conferred by the National Academy of “exoskeleton” for the soldier the man out of the loop.” He Engineering--viewed by many as composed of such things as novel continued: “Here you’re applying the engineering equivalent of the nanoparticles, electroreological fluids, [MIT’s] greatest strengths to helping Nobel Prize. This is intended to and polymer actuators could not the man or woman him- or herself.••• increase public understanding of the only provide ballistic protection, but contributions of engineers, especially also be transformed into a medical For more about the ISN... in technology, to the welfare and cast (on demand) or it could be http://web.mit.edu/ISN freedom of humanity. Langer was also awarded by the Chemical Heritage Foundation, the 2002 Othmer Gold Medal for his contribu- HEAD from page 12 his teaching and research responsibili- tions to science and medicine. (See ties; in addition, he is director of the article page 7) You may recall that especially in the areas of tenure and new Deshpande Center for Techno- the very first recipient of the same promotion. Beginning this academic logical Innovation.(See article medal was one of our own distin- year Professor Paula T. Hammond page 6) guished alumni – Ralph Landau. is now a tenured Associate Professor of chemical engineering. Professor The Deshpande Center is just one of This year Professor Klavs F. Jensen Hammond is a pioneer in that she several new programs and initiatives also was elected into the National is the first woman of African-Ameri- that have been instituted at the begin- Academy of Engineering for his can descent to achieve tenure in the ning of the academic year 2002-2003. contributions to multi-scale chemical entire School of Engineering. Profes- Thanks to a generous gift of $20 reaction engineering. sor Linda G. Griffith is now Full million from Jaishree Deshpande and (See article page 6) Professor of chemical and biological Desh Deshpande, the Center has engineering in the Department. We been created with the mission of Professor Douglas A. Lauffenburger are very proud of the accom- focusing on the support of leading was selected as recipient of the 2002 plishments of these two important edge research on new and emerging AIChE William Walker Award for members of our Department, and you technologies, and fostering the inter- excellence in research publications. can find more details on each of them actions between MIT and entrepre- (See article page 21) later in this newsletter. neurs from outside the Institute. Also, (See articles page 5) thanks to the leadership of several of Professor Gregory Stephanopoulos, our faculty members, namely Profes- who was recently named the Bayer Also this year, we have as Visiting sor Alice P. Gast, Vice President Professor of Chemical Engineering, Professor of Chemical Engineering, for Research and Associate Provost was awarded the 2002 Merck Award Richard D. Braatz, Professor and of the Institute, Professor Paula T. in Metabolic Engineering; he was University Scholar at the University Hammond, and Professor and Insti- also elected to the Board of Directors of Illinois at Urbana-Champaign. tute Provost Robert A. Brown, MIT of the American Institute of Chemical Professor Braatz will be teaching a has been awarded a $50 million, Engineers (AIChE). As you can tell, course in systems engineering during 5-year contract with the United our faculty, in addition to their dedica- the Spring 2003 term. We are also States Army to set up the Institute tion to research and teaching, are also pleased to welcome back from leave for Soldier Nanotechnologies, whose highly regarded and respected by their of absence and sabbatical, respec- main project is to develop lightweight peers in the discipline. tively, Professors George Stepha- molecular materials which can be nopoulos and Charles L. Cooney. used to create self-healing and protec- I hope that you enjoy this issue of Professor Stephanopoulos was Execu- tive gear that will protect soldiers the newsletter, and I encourage you tive Managing Officer and Chief from chemical or biological weapons. to write us to let us know how Technology Officer at Mitsubishi (See article page 16) you are doing. Thank you all for Chemical in Tokyo, Japan. Professor your support and best wishes for the Cooney spent his sabbatical year at Also in the newsletter you can coming year!••• the University of Cambridge. Upon read about MIT exciting alliance returning to campus, he has resumed with Dupont, DMA, which is led 17 News From Alumni/ae

OF THE DEPARTMENT OF CHEMICAL ENGINEERING •••

Photo: Brian Ashton Cripple the Medical Device Indus- Outstanding Teaching in the Life try.” It can be read or downloaded Sciences from Brown University. from http://www.cato.org or requested After a career in the Biotechnology via email ([email protected]). and Medical Device Industries, he Homsy reports that his 6 months at joined the faculty at Brown where he the Practice School were some of the is currently Professor of Medical Sci- most helpful and enjoyable months ences and Engineering, and Director of his life. After completing his of Brown’s Center for Biomedical ScD under Hoyt Hottel, and along the Engineering.••• way serving as Practice School Asst. Director (1955-56), he was appointed ames McCauley ’51 wrote in rian Ashton ’52, and his wife as a Fulbright Scholar in the UK report that he’s had a fulfilling Margaret (See photo above) (1957-58). Since then, much of his Jcareer. First he served as V.P. for Bare happy to be home in their professional life has been spent expe- Research, Development and Engineer- native Cape Town, South Africa. After riencing the subject matter of the ing at Crucible Steel Corporation, graduating from MIT, Ashton worked Policy Analysis. Now retired, he is and then as V.P. for Development and for Hydrocarbon Research, Inc. in doing a little consulting, but mainly Engineering at Sharon Steel Corpo- New York, then after a brief return enjoying his 6 yr. old grandson and ration until 1979 when he became the home, he began a new position in 23 month-old grand-daughter, and his owner of Emeco, Inc.••• the Research Division of Distiller’s children, both of whom are post- Company in London, England. After graduate medical students.••• ans Morgenstern ’58 recently four years he returned to Cape Town, retired from the U.S. Air where he worked for AA Distilleries HForce, in which he pursued and Wines, Ltd. until about 1968 a rich and interesting career first as when the company was taken over by a Training Officer, then as a Course a competitor. Ashton then worked for Development Instructor. He now Amalgamated Launderies for two works as a consultant through HGM years, and in 1974 bought Vitria Associates in the fields of Chemical, Glassware. He remains active with Environmental, Materials and Safety Vitria, which wholesales, decorates Engineering.••• and cuts glassware and lead crystal, although his son François now runs alter R. Niessen ’60 is the company. Despite some health pleased to share his good complications, Ashton still enjoys Wnews! The third edition of yachting, tennis, and skiing.••• Niessen’s latest book, Environmental Science and Pollution Control Series: kbar F. Brinsmade MS ’42, Published by: Marcel Dekker Web: http://www.dekker.com Combustion and Incineration Pro- is congratulated for his cesses (Pub: Marcel Dekker) was Aselection for the 2002 edition Tel: (800) 228-1160 released in Spring 2002, offering of Who’s Who in America.••• one of the most comprehensive and avid Karohl ’85/PS ’86 authoritative books available for this abriel “Gabe” de Roetth ’44 reports that after 13 years complex field. Environmental Engi- is staying active, working as Dworking for Solvay in the neering reviewers commented, “a Ga part-time substitute teacher hydrogen peroxide and HDPE busi- must...contains a wealth of informa- in three high schools near his home nesses--the first 7 years in production tion” See ordering information (L). ••• in Kihei, on the Hawaiian island of and R&D and the final 6 years in Maui. He and his wife Maricruz, also marketing and business develop- atesh Parashurama ’94 wrote enjoy summer sojourns in the lakes ment--he departed to attend business in to report that after two years region near Coeur d’Alene, Idaho.••• school full time. Shortly after Nof working in General Surgery completing his MBA at Rice Univer- at Boston Medical Center, he entered harles Homsy (X-B) ’53/ScD sity in May 2001, he joined the Busi- the PhD program at Rutgers Univer- ’59, is pleased to share the ness Development team at Carbon sity in Chemical Engineering. Para- Cnews that The Cato Institute, Nanotechnologies, Inc. (CNI).••• shurama, already an MD, is excited a Washington DC libertarian think about the opportunity to use ChemE tank, on August 28, 2001 published ichael Lysaght ’64 recently methods for studying surgical his policy analysis, “How FDA received the Elizabeth problems.••• Regulation and Injury Litigation MLeDuc Award for 18 2002 ChE Alumni/ae Reception THE FLAGSHIP Class of 1952 • June 7, 2002 Photo: Gregory Sands

The School of Chemical FRONT ROW (L to R): Peter Melnik, Bill Dunn, and Steve Learnard. MIDDLE ROW Engineering Practice, 1916-1991 (L to R): Sam Mitchell, Dirk Plummer, Cliff Sayer, Dick Heitman, and Allan Chin. BACK ROW (L to R): Bob Damon, Joe Moore, Amos Dixon, Bob Bacastow, Manuel By John I. Mattill, Editor Emeritus, Liberman, Bob Lurie and Nick Haritatos. Technology Review

190 pages, 120 photographs, scores of anecdotes, and three reminiscences by alumni/ae capture the special passion of this audacious - and still unique - concept that has become a world Lurie Lures Lockhart Into standard for engineering education To Order: Send US $20 per copy plus Slide Rule Conducting Debut! $2 per order for postage and handling ($5 foreign) to: he department and Department of Chemical Engineering TMIT Alumni Associa- MIT, Room 66-309 tion convey special thanks Cambridge, MA 02139 to Robert M. Lurie ’52 (R) who was instrumental Make Checks Payable To: in encouraging alumni/ae David H. Koch School of Chemical to visit our Alumni/ae Engineering Practice Reception this year, held in the Lewis Room on MIT Commencement Day, June Photo:Boston Symphony Orchestra What’s the latest from MIT’s 7th. Lurie also provided Association Alumni/ae Photo: MIT Department of Chemical Boston Pops Conductor Engineering? Keith Lockhart (R,bottom) with a special MIT baton http://web.mit.edu/cheme/ -- an engraved slide rule, with which he conducted For MIT ChemE News, Career chorus and orchestra in Resources and Program the “Star Spangled Information please visit us Banner” at this year’s on the World Wide Web MIT Night at the Pops.

19 There’s No Substitute for Hands-On Experience Cain, Roos’44, Evans Investment Helps Boost Value and Power of ChemE’s Undergraduate Lab Curriculum

ight spills through the parting opportunities for ChemE Jr’s and Photo: Gregory Sands elevator doors after a long Sr’s to apply theoretical knowledge, Lplunge through the heart of exercise teamwork and collaboration building 66. Did you press the skills, and gain familiarity with right button? The floor indicator says laboratory equipment, procedures and “SB”-sub-basement, yet instead of a practices. dreary dark cave, there’s a bright, modern, spacious, and well-equipped Previously, these courses shared space new research facility. “Maybe,” you distributed over several floors or even think, “the elevator is lying.” If you several buildings, adding logistical did--you’d be wrong! complications for students and teach- ers alike. Specialized equipment, par- Welcome to ChemE’s new subterra- ticularly for bio-related projects was nean undergraduate teaching labora- in short supply and sometimes fixing tory, generously funded with the help or improvising substitutes consumed of lead gifts from the Gordon A. and critical planning and implementation Chris Bettinger ’04 (R) explains his Mary Cain Foundation and from time. A new undergraduate lab project to visiting lab donors Edwin Edwin G. Roos ’44 and his wife, subject, 10.28 Biological Engineer- G. Roos ’44 (C) and Mary Ann Mary Ann Evans, and contributions ing Laboratory, will share this space Evans(L). from a large number of alumni and beginning next year. friends of the Department. At last, our undergraduate process and project lab which offers exhaust port capabilities courses have a unified home! We are throughout the lab. Varying electrical very grateful to all those who made requirements of lab appliances such as this possible. ovens will be filled by the use of overhead “buss bars” which safely This new facility, finished in Spring provide the variable voltage and watt- 2002, was constructed in response age for multiple appliances having to a dramatic increase in numbers Sands Photo: Gregory different requirements. of ChemE majors, the emergence of Bioengineering as a prominent One-third of the new lab is devoted focal point, the need to more effec- to Bioengineering facilities, including tively maximize student/faculty con- BL1 and BL2 areas separated by tact time by consolidating lab space, L to R: ChE Industrial Development window-walls for projects involving and the need for reliable, state-of-the- Officer Dr. Barry Johnston, Dept. cell growth and cell cultures as well as art equipment. Head Robert C. Armstrong, Donors separations. Edwin G. Roos ’44 and Mary Ann Each of our two undergraduate lab Evans, and ChE Executive Officer To maximize exhaust-handling courses to be housed in the new Karen K. Gleason (Background L to R: capabilities, new dedicated exhaust space, 10.26 Project Lab and 10.27 Arthur D. Little ’85, William H. McAdams blowers were installed. Unlike Processes Lab offers unique ’17, and William P. Ryan ’17). exhaust hoods in other parts of the building, which are vented by a Photo: Gregory Sands What’s Inside central blower via a complex duct To address the need for better space network, those in the subbasement are management and flexibility, reliable served by a system which vents and up-to-date equipment, proper subbasement exhaust directly to the bioengineering facilities, the rein- roof. forcement of team-work and collab- orative learning, and compliance with Within an empty duct-way which ADA (Americans with Disabilities was included as part of the Landau Act) regulations, the new lab design building’s original construction but has a number of important features. never used, Facilities Manager Steve Space management will be made Wetzel and lab designers installed Low-rise exhaust hood (L) permits easier, with rolling benches and a dedicated exhaust duct which easier access for wheelchair and cabinets --for easy configuration of will ensure that the new lab’s exhaust other handicapped students. multiple apparatuses where needed, and a spiral duct exhaust-system NEW LAB see facing page

20 NEW LAB from facing page helps maximize the value of time spent in the lab area. Students may needs are met at least as well as those easily shift back and forth between 10.26 is rare, if not unique above ground level. To further max- meetings, and lab work, wasting mini- in the nation. Sponsored by imize system efficiency and reliabil- mal time on meetings-logistics. industry and supervised by ity, suction is driven by an alternating Chemical Engineering faculty, the pair of roof blowers, rather than a experiments selected for this one- single unit. Other centralized facilities Photo: Gregory Sands semester course pose real-world include dedicated compressed gases, problems in need of real-world de-ionized and chilled water. answers. Working in groups on a single experiment, which lasts the Another important improvement is duration of the course, students handicapped accessibility, which has often must design, specify, and been enhanced by such features as assemble equipment prior to low rise exhaust hoods which allow conducting experiments. They are seated wheelchair students to work introduced to novel topics and comfortably on projects requiring the manage the projects from proposal use of an exhaust hood. and planning to execution and reporting. The five-person teams Teamwork and collaboration are a include three students, a faculty critical part of the ChemE undergrad member, and a company ChE Facilities Manager lab experience. The new Edwin G. representative, with whom students Steve Wetzel with new roof Roos ’44 and Mary Ann Evans maintain ongoing involvement. mounted dual-exhaust blowers. Room supports these important activi- ties with a generously appointed con- 10.27is a one-semester course ference room immediately adjoining Keeping Pace with Technology giving students experience in unit the lab space complete with spacious In the future we hope to establish operations. Students work in teams white boards, student lockers, and a companion endowment, which will of three on three open-ended conference table. Smaller meeting help maintain and update experi- experiments that cover various areas, all brightly lit with spacious ments, supplies, and equipment for chemical engineering subjects. whiteboards are also available. the future. This investment will What sets Processes Lab apart is Having these facilities nearby, all with enable the labs to keep up with that the experiments on a single windows overlooking the labspace, advances in the field, permitting topic are progressive within the cutting-edge experiments to be semester, allowing students not only Photo: Gregory Sands added and existing experiments to compare results, but also to build to be revised as technology evolves. on the results of previous teams. The experiments are selected to With warm gratitude we thank the illustrate traditional subjects, such Gordon A. and Mary Cain as distillation, fermentation, and Foundation and Edwin G. Roos ’44 reaction kinetics, and newer topics, and Mary Ann Evans for their including chemical vapor visionary investment in helping depostion and pressure swing prepare tomorrow’s innovative Edwin G. Roos ’44 and Mary adsorption. Ann Evans Project Room. engineering graduates!••• Lauffenburger Wins Election to NAE and AAAS

Photo: Stu Rosner Director of the new Biological Congratulations to Professor Engineering Division, and Director Lauffenburger on this impressive of Biotechnology Process Engineer- dual honor!••• ing Center who was elected both as a Fellow of the American Academy of For more about Lauffenburger... Arts and Sciences, and as a Member http://web.mit.edu/cbe/dallab/doug.htm of the National Academy of Engineering since our last For more about the National Academy Newsletter. of Engineering... http://www.nae.gov Lauffenburger was cited for pioneer- Professor Douglas A. Lauffenburger ing contributions in the application For more about the American he Department of Chemical of engineering in molecular and cell Academy of Sciences... Engineering is proud to biology and to a quantitative under- http://www.amacad.org/index.htm Trecognize Professor Douglas A. standing of molecular and cellular Lauffenburger, J.R. Mares Profes- processes and for his leadership in the sor of Chemical Engineering, Co- bioengineering community. 21 New Alliance Shares Biotech Strengths, Benefits

hat happens when a bio-tech Research Funding Fellows in 8 departments. In savvy research university For its initial set of research 2001-2002, the fellowship program Wteams up with a chemical programs, the DMA Steering Com- was expanded to 20 DuPont Fellows industry-giant to maximize their mittee in August 2000, selected 10 in 10 departments and centers, reflect- collective biotechnology “smarts”? proposals from a field of 37 submis- ing the broader participation in DMA sions from MIT faculty. Varying in research activities at the Institute. ChemE faculty members Robert A. cost, size, and complexity, the funding Brown (MIT Provost), Robert E. for the selected projects ranged from In each of the first two years of the Cohen and Douglas A. Lauffen- $100K per year to large, multi-investi- Fellowship program, the DuPont burger recently initiated just such an gator projects at $1M per year. Fellows were invited as a group to exciting partnership. Officially begun visit the Experimental Station and on January 1, 2000, the Dupont-MIT DMA has since then executed four other DuPont facilities in Wilmington. Alliance is now a thriving addition more rounds of proposal solicitation This unusual opportunity was received to existing campus-industry collabora- and review. Overall, 75 applications with great enthusiasm by the students. tions, and bears strong ties to ChemE for research funding were received with Cohen and Lauffenburger co- by DMA and an open solicitation pro- “The seminar was really enriching as directing the Alliance’s MIT activities, cess is now accepting white papers it showed us a glimpse of the indus- and Brown serving with Thomas M. throughout the year for review. trial world. Also, having the opportu- Connelly of Dupont as Co-Chair of nity to talk with several DuPont sci- the DMA Steering Committee. entists was really great, as I learned MIT a lot from these conversations, espe- The MIT/ DuPont partnership is DUPONT cially about biomaterials,” remarked emblematic of DuPont’s increased one DMA Fellow. Another com- emphasis on life sciences in the past ALLIANCE mented, “The visit gave me a good several years. “DuPont has tradi- “It’s essential to maintain an aca- insight on DuPont’s efforts to adapt tionally been very strong in chemi- demic environment in which first- pro-actively to the new business cals, and polymer and inorganic mate- year graduate students can freely environment. Definitely valuable.” rials,” according to Bruce E. Smart, explore options for their thesis research manager in the biochemcial research project, unencumbered MIT faculty presentations in sciences and engineering section of by considerations of need for Wilmington have included six one- DuPont Central Research and Devel- immediate financial support of day tutorials, covering topics of a opment and the company’s Program their educational program. This “character-changing” nature for the Director for the Alliance. “But we feel is particularly important for those professional staff at the Experimental the future of DuPont is at the interface who may be attracted to projects Station. In Summer 2001, there were of chemistry, materials science, and with multiple research advisors two short course presentations. biology. The resulting technologies working in areas outside the range Professors Daniel I.C. Wang and will represent the new growth oppor- of the student’s undergraduate Charles C. Cooney presented tunities for the company.” experience.” Fermentation Technology, and a Metabolic Engineering and The Alliance supports research proj- Robert E. Cohen,Alliance Co-Director Bioinformatics course was given by ects that draw upon the science, engi- Professor of Chemical Engineering Professors Gregory Stephanopoulos neering and business expertise at MIT and Anthony Sinskey. In June 2002, and that extend and better leverage At present, there are 17 funded Professors Harvey Lodish, Paul the reach of DuPont’s scientific exper- programs involving 46 faculty from Matsudaira, Bruce Tidor, and tise in the areas of biology, genetics, 13 different departments, centers and Alexander Klibanov presented an bioinformatics, and catalysis. This divisions at MIT. Each of the 17 executive tutorial in Biotechnology, joins DuPont’s and MIT’s strengths programs has one or more closely- and eight DuPont professionals in materials, chemical and biological connected liaisons at the DuPont attended the Promoting Innovation: sciences to develop new processes for Experimental Station. The Dynamics of Technology and new materials directed at bioelectron- Organizations course at the Sloan ics, biosensors, biomimetic materials, Educational Programs School. alternative energy sources, and new DMA’s educational activities include high-value materials. fellowships for entering graduate With this dynamic blend of educa- students, tutorials by individual MIT tional programs, research sponsorship, Brown said, “We are extremely faculty presented at the Experimental and resource-sharing, we look forward excited about the opportunity to work Station in Wilmington as well as to a bright future for the new DuPont- together with DuPont to help shape multi-day short courses presented at MIT Alliance and the increased vital- the application of modern biology to MIT and DuPont. ity it promises for both distinguished a new range of materials and products partners, and the Chemical Engineer- for the benefit of society.” In 2000-2001 there were 14 DuPont ing community in general.•••

22 Alumni Donors

FOR THE PERIOD JULY 1, 2001 THROUGH JUNE 30, 2002 Thank you for all of your generous support throughout the year! Please direct corrections to: Gregory Sands, Editor Email: [email protected] • Phone: (617) 253-0949 • Fax: (617) 258-0546

Michael J. Abadi ’78 William A. Arnold ’94 William C. Behrmann ’60 Robert F. Abbanat ’50 Richard S. Arold ’65 Myron W. Belaga ’52 James D. Abbott ’32 Baffour Asante-Abedi ’00 Louis S. Belknap ’53 Stanley Abkowitz ’48 Wesley L. Asbury Jr. ’80 Norton Belknap ’50 Lily Ablondi ’82 Arjang A. Assad ’71 Samuel A. Bell ’33 Leah C. Abraham ’93 Frederick F. Assmann ’36 Barbara A. Belt ’77 Harold L. Abroms ’48 Kenneth J. Auer ’58 Luca F. Bencini-Tibo ’74 David E. Acker ’38 Anne H. Aunins ’91 Douglas F. Bender ’70 David D. Adams ’50 John G. Aunins ’89 Lewis H. Bender ’81 David G. Adler ’60 Harold R. Austin ’55 Kevin E. Bennet ’76 Noubar B. Afeyan ’87 James A. Avallon ’79 Robert F. Bennett Jr. ’71 Sumit Agarwal ’98 Henry Avery ’41 Thomas M. Bennett ’43 Kevin A. Agatstein ’97 Oliver H. Axtell Jr. ’47 Bernard A. Benson ’56 Peter P. Agoston ’45 Alfred B. Babcock Jr. ’43 George K. Benson ’51 Rakesh Agrawal ’80 William L. Babcock ’41 Paul F. Bente ’68 Ronald D. Agronin ’60 Robert B. Bacastow ’52 Maurice C. Beren ’28 Berit S. Ahmad ’97 Brett W. Bader ’95 Peter E. Berger ’97 Edward S. Ahn ’97 Jamie B. Bader ’80 Scott A. Berger ’78 Paul C. Ahrens ’74 Kamran Badizadegan ’88 Richard I. Bergman ’55 Gordon Aitken ’54 Henry C. Baer Jr. ’48 Michael L. Berins ’60 John J. Alam ’82 Tina Bahadori ’84 David P. Berkowitz ’84 Ashwin G. Alankar ’96 Anna Bailey ’54 Edwin L. Berkowitz ’56 Charles F. Albright Jr. ’80 James H. Baird ’40 Leonard Berkowitz ’58 Joo H. Albritton ’79 James L. Baird ’40 Howard S. Berman ’82 William R. Alcorn ’57 Marshall E. Baker ’48 Sofia T. Bermudez ’94 James S. Alder ’72 Lionel V. Baldwin ’55 Peter F. Bernhardt ’82 Collin H. Alexander ’39 Jean F. Bandy ’80 Alan M. Bernstein ’68 Gregory L. Alexander ’78 Eric T. Banks ’84 Howard Bernstein ’85 Richard G. Alexander ’49 Donn W. Barber ’42 Pamela C. Berry ’79 Paschalis Alexandridis ’90 Karen G. Bardeen ’87 William H. Bertolet III ’48 George Alexopoulos ’92 Aaron A. Barlow ’86 Robert J. Best ’40 Ernest J. Allard Jr. ’53 Donald W. Barnby ’56 Albert W. Beucker ’40 Herbert K. Allbright ’31 James H. Barnes Jr. ’44 Edmund M. Bevington ’49 Jonathan O. Allen ’93 Robert E. Baron ’81 Stefan K. Bewley ’01 Phillip B. Allen ’60 Michael D. Barrera ’90 Pauli M. Bhadha ’81 Scott W. Allison ’62 Rodolfo F. Barrera ’49 Nazir A. Bhagat ’66 Diana M. Altrichter ’80 Hope M. Barrett ’98 Wayne W. Bidstrup ’88 John F. Alvarez ’73 Chester T. Barry ’83 Robert F. Biehl a ’56 Maureen C. Alvarez ’75 Alfred P. Barton ’40 Edwin J. Bielecki ’44 Allen C. Amdur ’48 Thomas M. Bartos ’85 John E. Bigelow ’56 Illa L. Amerson ’91 Osman A. Basaran ’78 Charles J. Billerbeck ’55 Paul R. Ammann ’57 Louis Basel ’49 Bradley C. Billetdeaux ’72 Charles D. Anderson ’62 Jesse N. Baskir ’88 Charles W. Billings ’83 David J. Anderson ’86 Alan G. Bates ’50 Tara F. Bishop ’97 Eric W. Anderson ’79 Chiranjiv Batra ’51 Thomas W. Bither ’82 James S. Anderson ’62 Claude P. Battu ’70 Harris J. Bixler ’53 John E. Anderson ’50 William H. Battye ’77 Donald T. Black ’71 Steven J. Anderson ’78 Ronald O. Baukol ’60 Kathleen M. Black ’50 Robert L. Andrews ’61 Alfred G. Baum ’48 Donald S. Blackford ’57 Andres T. Ang ’58 Stephen H. Baum ’64 James J. Blake ’58 Laura C. Angotti ’86 Yvette V. Baxter-Drayton ’91 Owen W. Blake Jr. ’65 Alfred J. Antos ’82 Douglas M. Bea ’88 Joanna D. Blanchard ’99 Kaoru Aou ’00 Malcolm C. Beaverstock ’63 Fernando Blasco-Moreno ’74 Minas R. Apelian ’88 William C. Beck Jr. ’62 Saul Blinder ’55 Gerald M. Appelstein ’80 William F. Beck ’64 Ellen F. Block ’95 Mark A. Applegate ’92 Henry A. Becker ’61 Lawrence W. Blodgett ’56 Prashant B. Arce Doshi ’95 David R. Beckerman ’60 William D. Bloebaum Jr. ’62 Webster J. Arceneaux Jr. ’55 Lloyd S. Beckett Jr. ’56 Lloyd M. Bloom ’82 Debra B. Arenare ’87 Norman Beecher ’44 Daniel F. Blossey ’64 Antonio A. Armenante ’49 George J. Beerli ’57 Malcolm R. Blotner ’56 23 Emanuel M. Blue ’37 Richard F. Brown ’82 Thomas S. Chang ’81 Paul N. Blumberg ’65 Rodney F. Brown ’78 Steven H. Chansky ’67 Robert L. Blumberg ’64 Roy W. Brown ’40 Enoch I. Chao ’76 Theresa Bly ’01 Stephanie J. Browning ’98 Stanley E. Charm ’52 Thomas C. Boberg ’56 James S. Bruce ’39 Anita L. Chaudhuri ’01 James A. Bock ’43 Scott R. Brundage ’80 Joanne Y. Chee ’89 Richard E. Bockrath ’82 Raymond F. Brunsberg ’86 Marc J. Chelemer ’81 Herman N. Bockstruck ’50 Robert L. Bryan ’39 Caroline P. Chen ’00 Theodore H. Bodner ’53 Gina M. Buccellato ’86 Jennifer C. Chen ’85 Norman W. Boe ’70 Evan Buck ’61 John C. Chen ’84 John T. Boepple ’71 Walter F. Buck ’55 Ming-Ming Chen ’73 Nelson T. Bogart Jr. ’39 Paul A. Buckingham ’48 Nai Y. Chen ’59 George E. Bohlig ’57 Walter M. Buehl Jr. ’59 Nora Chen ’97 William H. Bohlke ’65 Gordon M. Burck ’75 Shiao-Chiu A. Chen ’58 Robert E. Bohman ’77 Maria K. Burka ’69 Stephanie S. Cheng ’00 Douglas G. Bohn ’98 James C. Burns ’57 Wu-Cheng Cheng ’79 Vivek Bohra ’96 James L. Burns ’47 Martin R. Chetron ’56 Michael P. Bohrer ’75 William A. Burns ’61 Bo K. Chi ’79 Richard C. Boland ’80 Joseph T. Burval ’58 John S. Child Jr. ’67 Justin C. Bolger ’61 Claudia W. Buser ’81 John V. Childerhose ’48 Richard N. Bolles ’50 Ellen R. Bush ’81 James L. Childs Jr. ’82 Andreas S. Bommarius ’82 Rhonda L. Bush ’00 Catherine Chiles ’78 George W. Bond ’57 Harold W. Butler ’38 Arthur A. Chin ’80 Leo W. Bonnell ’77 James C. Butler ’86 Michael Q. Chin ’79 John S. Bonner ’50 Mark L. Bye ’78 Patrick K. Chin ’85 Joanna C. Bonventre ’02 Joseph Byrne ’50 Morris A. Chomitz ’46 Merson Booth ’55 Rodney D. Cadanau ’80 Martha A. Choroszy-Marshall ’79 James R. Boots ’80 Wayman L. Calhoun ’49 Howard W. Chou ’76 Rene F. Borbon ’95 Frank M. Calkins ’50 Oscar K. Chow ’78 Walter E. Borden III ’45 James R. Calkins ’50 Don A. Christensen ’52 Daniel B. Borenstein ’57 Donald A. Cameron ’57 David Christison ’42 Edward D. Boston ’49 David A. Campanella ’76 Jane H. Chronis ’80 Nicole A. Botcheos ’00 Alice E. Campbell ’78 Karen I. Chu ’94 Gregory D. Botsaris ’59 Calvin A. Campbell ’59 Paul Chuberka ’61 Van T. Boughton Jr. ’49 Sean C. Campbell ’92 Matthew B. Chun ’99 Alain L. Bourhis ’89 Thomas D. Canby ’52 Joyce A. Chung ’85 Jewell R. Bowen ’56 Alejandro Cano Ruiz ’91 Michael K. Chung ’94 Vernon O. Bowles ’33 Edward B. Cantey Jr. ’50 Dudley F. Church ’47 Walker H. Bowman ’51 Mark C. Capone ’91 Anna B. Chwang ’95 Thomas J. Boyle ’57 Anthony R. Cappuccio ’48 Jack J. Cinque ’53 Carl R. Bozzuto ’69 Farrokh K. Captain ’66 Stanley W. Clark ’57 Ralph Braccio ’81 John C. Card ’81 Donald K. Clarkson ’75 Walter D. Braddock ’58 Frank Cariello ’80 David D. Claypool ’63 John M. Bradley ’47 Rudolf Carl ’47 Don A. Clayton ’83 George B. Bradshaw Jr. ’40 John T. Carleton ’42 Frank L. Cleary ’56 Eugene G. Branca ’31 Edwin A. Carlson ’62 Robert C. Clement ’47 Robert L. Bratzler ’75 Harrison C. Carlson ’34 George F. Clifford ’48 James C. Bray ’72 Kristine S. Carlson Burgess ’88 Jason A. Cline ’97 Bruce B. Bredehoft ’56 Thomas W. Carmody ’44 Leslie W. Cline Jr. ’49 Kristen A. Breslin ’94 James M. Carr ’78 Herschel Clopper ’62 Christopher M. Brewer ’83 John Carrier ’95 Joseph A. Clumpner ’55 Barry W. Brian ’77 Hilary B. Carter ’00 James T. Cobb Jr. ’60 P. L. T. Brian ’56 Renee O. Carter ’77 Benjamin P. Coe ’53 Charles R. Bridges Jr. ’85 Thomas J. Carter Jr. ’57 Jerome T. Coe ’42 Amiel W. Brinkley Jr. ’50 Brian C. Carty ’85 Jerry A. Cogan Jr. ’58 Norman F. Brockmeier ’66 Robert J. Casadonte ’94 Alan P. Cohen ’75 James J. Broderick ’50 Leslie C. Case ’52 Edward S. Cohen ’50 Mitchell B. Brodkin ’61 Robert B. Case ’43 Harold Cohen ’87 Leslie G. Bromwell ’61 Pierre D. Casimir-Lambert ’55 Stephen I. Cohen ’60 James C. Bronfenbrenner ’70 Marion A. Casserberg ’94 Steven Cohen ’68 Barry R. Bronfin ’60 John R. Castle ’61 Jerald A. Cole ’82 Mary-Ellin Brooks ’94 Lawrence H. Cater ’80 Randolph P. Cole ’69 Daniel L. Brown ’55 Luigi A. Cazzaniga ’91 Scott H. Coleman ’96 David Brown ’40 William H. Ceckler ’61 Frederick L. Colhoun ’95 Douglas R. Brown ’75 Joseph Cerami ’86 Jeffrey L. Collett ’84 Frances S. Brown ’79 Karen M. Cervoni ’98 David J. Collins ’86 Frank R. Brown ’60 Albert P. Chadourne Jr. ’58 William P. Colman ’45 Henry T. Brown ’56 Belinda L. Chan ’96 Grace E. Colon ’95 James C. Brown ’96 Charmaine W. Chan ’95 Kim Colon ’90 James W. Brown ’54 Irene Y. Chan ’76 Stewart L. Colten ’64 John J. Brown ’32 Jennifer M. Chan ’92 Clark K. Colton ’69 Malcolm K. Brown ’66 Leonard B. Chandler ’36 Michael J. Colucci ’82 Patricia M. Brown ’78 Chiechun J. Chang ’83 James M. Colville Jr. ’73 Paul S. Brown ’59 David M. Chang ’78 Lloyd N. Combs ’33 Peter Brown ’62 Nancy T. Chang ’87 Kathryn J. Comer ’91 24 Ann R. Comfort ’88 Bernard E. Deitrick ’81 David K. Dyck ’81 Winthrop D. Comley ’37 Joseph A. Dellorto ’79 Peter D. Dyke ’56 John P. Congalidis ’81 Duncan J. del Toro ’66 Richard W. Dykstra ’79 Donald J. Conklin ’74 James P. Demakes ’36 Brian E. Eaton ’77 Catherine D. Conley ’96 John J. Demo ’35 Carl D. Eben ’61 Michael J. Connair ’48 Douglas Denholm ’78 Walter S. Eberhard ’42 Richard A. Conti ’84 Clifford M. Denker ’84 Thomas G. Eccles ’86 Edward T. Cook ’40 Yancy D. Dennis ’85 Ana T. Echaniz ’96 Garth Coombs ’51 Kathleen A. Dennison ’86 Matthew E. Edstrom ’95 Stuart L. Cooper ’63 Richard A. Denton ’36 Robert G. Edwards ’59 William W. Cooper ’63 Andre C. Deprez ’55 Timothy W. Eggert ’80 Steven S. Cooperman ’87 Daniel J. Dershowitz ’76 Christopher Egolf ’66 Terry M. Copeland ’78 Mark S. Dershowitz ’78 Tomoki Eguchi ’62 Bruce C. Copley ’78 C. R. Desper ’59 Ernest P. Eich ’65 George A. Corbin ’83 Patrice Desvigne-Nickens ’76 Ronald S. Eisinger ’70 Jennifer E. Corbin ’81 Bradley Dewey Jr. ’40 David M. Eissenberg ’52 Douglas H. Cortez ’69 Anthony J. Di Leo ’83 Ini A. Ekpenyong ’82 Claude Corty ’44 Sebastian M. Di Palma ’52 Eduardo F. Elejalde-Arena ’70 John D. Corwin ’50 Peter N. DiGiovanni ’67 Daniel L. Ellig ’81 Eric J. Costa ’82 Fiore D. DiGiovine ’51 Sandra C. Eltringham ’94 John L. Costello ’62 Paul A. DiMilla ’86 Tracy A. Embree ’95 Richard G. Cosway ’81 Francis A. DiTaranto ’83 Cherry L. Emerson ’41 John E. Cotter ’56 William A. Dickens ’56 Steven S. Emmer ’72 David B. Cotton ’58 Joseph W. Dickey ’66 Leonard L. Eng ’58 Robert H. Cotton ’39 Robert P. Dickey ’62 Bruce R. Entwistle ’82 Henry R. Couch Jr. ’59 Dana L. Dickinson ’73 Pablo Epstein ’51 Margaret M. Coughlan ’90 Steffen F. Dieckmann ’47 Shilpi Epstein ’94 Arthur Cowen ’57 Albert C. Dierckes Jr. ’60 Harold G. Erichs ’58 John O. Cowles ’56 Edward F. Dillon ’47 Walter R. Ericsson ’47 Benjamin D. Cowley ’49 Dimitrios G. Dimitriou ’50 John E. Ertel ’50 Paul M. Cox Jr. ’61 Carl A. Dimon ’58 Richard H. Eshbaugh ’35 Gordon S. Craig ’89 Ali K. Dincer ’75 Clifford J. Eskey ’85 Joseph J. Cramer ’68 Steven M. Dinh ’81 Ramon L. Espino ’68 John L. Crandall ’42 Keith E. Dionne ’90 Louis Essandoh ’77 Bruce E. Crocker ’64 Joseph M. Ditz ’68 Oscar C. Eubank ’50 James C. Cross ’87 Robert K. Dix ’43 James M. Evans ’56 Matthew S. Croughan ’88 Amos T. Dixon Jr. ’52 Timothy W. Evans ’73 Thomas S. Crow ’47 Daniel G. Dobryn ’85 Carl B. Everett ’69 Dolores Cruz ’00 Gonzalo C. Docal ’44 James M. Ewell ’37 Jeffrey J. Csernica ’89 John F. Dockum Jr. ’50 William Eykamp ’65 Orlando D. Cucchiara ’55 William G. Dodge ’31 Wilhelmina Fader ’85 Peter M. Cukor ’66 William W. Doerr ’79 Malcolm P. Fairbairn ’84 Thomas F. Cummings ’47 John F. Dolan ’80 Michael Falco ’59 Marie A. Cunningham ’85 Thomas J. Dolan ’43 James R. Falender ’65 Philip D. Cunningham ’62 Joseph D. Domine ’64 David M. Falk ’43 Tiffany P. Cunningham ’98 John E. Donahue ’48 Gary L. Falkenstein ’59 James A. Curme ’82 Dominic G. Donatello ’39 Gary J. Fallick ’58 Thomas A. Curtis ’80 Timothy J. Donnelly ’89 Kevin J. Fallon ’78 Linda M. Custer ’83 Francis J. Donohue ’45 Robert H. Fariss ’51 John M. Czarnowski ’93 James H. Donovan ’89 Dora Farkas ’98 Brian A. D’Amato ’96 William P. Dooley ’40 John Farquhar III ’54 John F. D’Amico ’54 Laurence E. Dowd ’44 Roger D. Farr ’79 Zaven A. Dadekian ’55 Mason L. Downing ’41 Joseph B. Farrell ’47 Carol A. Daigle ’80 Cyril W. Draffin Jr. ’72 Peter C. Farrell ’67 George A. Dainis ’81 Edna L. Dragsdorf ’49 Paul J. Farris ’60 Robert H. Damon ’52 Elisabeth M. Drake ’58 John E. Fay II ’71 John P. Daneman ’44 Javit A. Drake ’94 Joseph N. Feil ’60 Robert A. Dangel ’70 Peter A. Dreher ’80 Harvey L. Fein ’61 James R. Datesh ’77 James A. Drobile ’50 Alan S. Feitelberg ’90 Thonet C. Dauphine’ ’35 James M. Druding ’85 Lowell L. Fellinger ’41 Marc G. Davidson ’88 Andrew D. Dubner ’85 Flora W. Feng ’90 Dwight A. Davis ’71 Natalia Duchini ’01 Daniel J. Ferguson ’85 Gershon J. Davis ’56 Chase E. Duclos-Orsello ’00 Jose V. Ferrara ’54 Rebecca A. Davis ’87 Scott G. Dudevoir ’85 Joao P. Ferreira ’93 Robert W. Davis ’50 Barrett S. Duff ’50 Mary T. Ferris ’81 Richard P. De Filippi ’59 Norman B. Duffett ’40 Theodore V. Ferris ’41 Aida E. De Garcia ’88 George S. Dundon ’48 Theodore R. Fick ’52 Eleanor M. De Groot ’90 Deirdre K. Dunn ’99 Hunter H. Ficke ’77 Robert L. De Jong ’58 Dorsey C. Dunn ’61 Edwin L. Field ’50 Arnaud F. De Vitry D Avaucourt ’51 Parker S. Dunn ’31 Leslie A. Field ’78 Edward G. DeLaney ’48 William W. Dunn ’52 Allison A. Fielder ’02 Sheldon W. Dean Jr. ’58 Louis J. Durlofsky ’86 Francis E. Finch ’89 Tina S. Dear ’92 Preston L. Durrill ’57 Collin E. Fink ’33 Pablo G. Debenedetti ’85 James L. Dwyer ’54 Michael J. Fink ’81 Louis P. Deis Jr. ’52 Thomas J. Dwyer ’57 Stan N. Finkelstein ’71 25 James L. Fischer ’55 Brendan J. Geelan ’67 Frederick B. Grosselfinger ’38 Elizabeth A. Fisher ’80 David J. Geiser ’79 Philip M. Grover ’57 Robert E. Fisher ’66 David H. Geisler ’60 Reginald B. Grover ’57 Warren C. Fisher ’49 Fred Gelbard ’74 Martin J. Gruber ’59 James H. FitzGerald ’47 Lars H. Genieser ’94 Philip E. Gruber Jr. ’55 Bridget A. Fitzpatrick ’87 Frank T. Gentile ’88 Eugene L. Grumer ’64 Daniel L. Flamm ’64 Gregory S. George ’79 Irwin J. Gruverman ’55 Michael E. Flanagan ’85 Carl J. Giallombardo ’83 Raymond G. Gruwell ’51 William M. Flarsheim ’81 David A. Gibbs ’60 Paul F. Gubanc ’82 Raymond K. Flege ’32 Douglas J. Gilbert ’78 Thomas A. Gubiotti ’96 Daniel F. Flores Jr. ’85 Frank Gilliland ’52 Ernest A. Gudath ’60 Trinidad Flores ’92 Christian A. Gimre Jr. ’58 Amrita Guha ’00 Ethan A. Fode ’96 Kymus K. Ginwala ’52 John E. Gulick ’49 Harry G. Foden ’50 Gerard H. Gizinski ’67 Frank A. Gulla ’74 Stephen K. Fok ’80 George B. Glackin ’79 Heinz H. Gunther ’52 Ivan K. Fong ’83 Richard E. Gladstone ’40 John R. Gunther ’43 Wing S. Fong ’54 Werner B. Glass ’56 Frank E. Guptill ’48 Thomas Foo ’85 Karen K. Gleason ’82 Robert N. Gurnitz ’60 J. C. Forman ’53 Roland D. Glenn ’33 David E. Gushee ’50 Carl A. Fortin ’91 Peter A. Glenshaw ’59 Samuel Gusman ’46 John F. Foulis Jr. ’72 John J. Glover ’49 John A. Gutai Jr. ’50 William S. Foulks Jr. ’42 Simon E. Gluck ’43 Edgar B. Gutoff ’52 George N. Fountas ’48 Richard A. Gnecco ’50 Vincent Ha ’96 Russell A. Foust Jr. ’46 Michael R. Gobler ’89 Young Soo P. Ha ’85 Richard P. Fowler ’49 George A. Goepfert Jr. ’55 John C. Haas ’42 Daniel C. Fox ’90 Gary J. Goetz ’73 Robert A. Haass ’50 William K. Fraizer ’80 Cobb S. Goff ’70 Austin G. Habib ’57 Warren C. Francis ’40 Kent E. Goklen ’86 Nicholas Habibe ’56 Cheryl B. Francisco ’93 Robert H. Goldey ’44 David S. Hacker ’50 Raymond F. Frankel ’43 Morton I. Goldman ’50 P. F. Hagerty ’46 Howard D. Franklin ’80 Andrew H. Goldsmith ’67 Wilburt E. Haggerty ’50 Rufus M. Franklin ’47 Jonathan M. Goldstein ’83 Aaron F. Hahn ’45 William D. Franklin ’72 Robert W. Goldsworthy ’58 Chris K. Hahn ’58 Darryl M. Fraser ’80 Gustavo E. Gomez ’52 Edwin R. Hahn ’40 Malcolm D. Fraser ’60 Rafael Gonzalez Jr. ’94 Eddy R. Hair ’54 Richard W. Freedman ’76 Elizabeth M. Goodrich ’89 Mohammadreza Hajaligol ’81 Reed H. Freeman ’61 Neal F. Gordon ’89 Daniel J. Halbert ’81 John J. Freer ’58 Brian S. Gorin ’86 David J. Haley ’91 Frank E. French Jr. ’43 Geoffrey E. Goring ’49 Mitchell J. Halle ’49 Paul H. Fricke ’61 George D. Gould ’47 Benjamin D. Halpern ’43 Robert P. Fried ’46 Rene Goutte ’61 Michael E. Halpern ’55 Malcolm P. Friedman ’59 Thomas R. Gow Jr. ’80 Bruce K. Hamilton ’69 Bertram N. Fritz ’87 Christine J. Graham ’92 Philip G. Hampton ’77 Shinya Fukuda ’95 Gustavo E. Grampp ’92 Julie J. Han ’94 George J. Fuld ’53 Henry R. Grane ’48 Robert H. Handler ’43 Cindy W. Fung ’96 William J. Grant ’48 Jason Handwerker ’97 David L. Fung ’85 Maurice F. Granville ’39 Robert T. Hanlon ’85 Andrew P. Furman ’85 Jason A. Grapski ’94 John N. Hanson ’64 Richard C. Furman ’72 John L. Graumann ’54 Jon C. Hanson ’65 Morris I. Gabel ’40 Hope T. Gray ’91 Robert A. Hard ’57 Henry L. Gabelnick ’61 Robert B. Gray ’98 Michelle T. Hardiman ’00 Calvin T. Gabriel ’83 Frank R. Graziano ’77 Nicholas J. Haritatos ’52 David C. Gagne ’81 Catherine I. Greany ’78 John B. Harkness ’71 William D. Gaherty ’84 Milton J. Grebler ’63 Kenneth G. Harms ’51 Lewis H. Gaines ’66 Saverio G. Greco ’51 George S. Harrington ’41 Donald R. Galinat ’51 Harry J. Green Jr. ’38 George M. Harriott ’83 Sean A. Gallagher ’84 Sheldon L. Green ’48 Peter Harriott ’52 Peter M. Galland ’63 Robert J. Greenberg ’78 Grady W. Harris ’61 Lawrence B. Galpin ’67 Robert H. Greene ’56 Leonard Harris ’44 Frederick W. Gander ’42 Wayne M. Greene ’84 Marvin S. Harris ’55 Manfred Gans ’51 Robert B. Greenes ’42 Ray W. Harris ’50 Joseph M. Ganzer Bruna ’71 Sidney H. Greenfeld ’45 Brian M. Harrison ’97 Gary C. Ganzi ’68 Norman L. Greenman ’44 William J. Hart ’48 Charles J. Garbarini ’60 Gail Greenwald ’75 Samantha L. Hartemink ’98 Joaquin Garcia Barcena ’58 Roy F. Greenwald ’75 Gary L. Harting ’60 William M. Gardner Jr. ’53 Clarence L. Gregory Jr. ’51 John S. Hartman ’65 Thomas F. Garrett ’52 Paul Greiff ’55 Christine M. Hartmann ’98 Angel R. Garron-Torrez ’77 Gus M. Griffin ’39 Mark A. Hartney ’82 Joseph F. Gassette ’81 Thomas P. Griffin ’80 Heidi E. Harvey ’81 Joseph V. Gaven Jr. ’52 Kenton A. Griffis ’66 William H. Haslett Jr. ’61 Lee M. Gavens ’78 Donald A. Grindstaff ’69 James A. Hasse ’79 Thomas H. Gawronski ’62 Debra Gross ’77 William Y. Hata ’81 Kenneth S. Gayer ’98 Marc S. Gross ’55 Robert L. Hatch ’47 Christopher T. Geary ’78 Marta E. Gross ’80 Gary R. Hattery ’78 Adam G. Gebauer ’56 Philip M. Gross ’63 Robert D. Hawthorn ’54 26 Althea T. Haylett ’85 Harold B. Hopfenberg ’60 Dara T. Jeffries ’02 Hal P. Headley ’37 Harvey C. Hopkins Jr. ’51 David M. Jenkins ’59 Frank J. Hearl ’80 Bernd P. Hopp ’63 Robert D. Jenkins ’48 Craig L. Heath ’56 Allen F. Horn ’84 Rodman Jenkins ’46 Ralph L. Hegner ’39 William B. Horner ’52 James T. Jensen ’50 Adel E. Heiba ’79 Robert V. Horrigan ’44 Peter L. Jensen ’73 Harry J. Heineman Jr. ’42 Jane F. Hortelano ’94 Lewis T. Jester ’72 Edward W. Heinle ’82 William E. Horton ’56 Vinod K. Jhunjhunwala ’65 Nina M. Heinrich ’02 Joseph I. Horwitz ’93 Neil Jochelson ’68 Robert W. Heinze ’68 Anne K. Hou ’83 Adrain E. Johnson Jr. ’49 Richard E. Heitman ’52 Patrick B. Houghton ’82 Charles T. Johnson Jr. ’73 Joseph J. Helble Jr. ’87 James J. Hourihan Jr. ’48 Dana E. Johnson ’88 Mark G. Helder ’84 John H. Howell ’35 Douglas L. Johnson ’53 John D. Helferich ’79 Matthew P. Howell ’94 Harry E. Johnson ’83 Steven Heller ’43 Edward L. Hoyt ’57 Ivette M. Johnson ’97 Richard K. Helling ’86 Sherry H. Hsiung ’95 John R. Johnson Jr. ’60 Kelly L. Hellmuth ’00 Shih-Liang Hsu ’60 Robert A. Johnson ’62 Charles B. Henderson ’52 Benjamin V. Hu ’79 Robert H. Johnston ’45 James H. Henderson Jr. ’42 Evelyn Y. Huang ’99 David H. Jones ’65 Donald L. Hendrickson ’50 Mengchien C. Huang ’54 Robert D. Jones ’86 D. B. Henschel ’67 Nganfong Huang ’02 Russell L. Jones ’72 David C. Herak ’89 Dennis J. Huber ’74 Stephen F. Jones ’76 Mark J. Herbst ’73 Robert T. Hucks Jr. ’51 Arnold S. Judson ’47 Gilbert R. Hernandez ’95 Timothy G. Hueston ’84 Burton F. Judson ’48 Linda R. Hernandez ’93 John E. Hueter ’71 Nikola M. Juhasz ’92 Jorge C. Herrera ’81 George A. Huff Jr. ’82 Lisa B. Jungherr ’81 Eduardo F. Herrerias ’43 Robert L. Huffman Sr.. ’42 Beth H. Junker ’89 Howard J. Herzog ’74 Donald P. Hug ’47 Nicholas C. Kafes ’55 Sidney W. Hess ’53 Mark D. Hughes ’79 Naomi J. Kagetsu ’82 Ann M. Hession Botelho ’90 Thomas P. Hui ’75 Burton H. Kahn ’47 Bedrich V. Hettich ’43 Lewis W. Hull ’38 Morley D. Kahn ’51 Jon M. Heuss ’62 Robert D. Hulse ’68 Muhammad R. Kaimuddin ’01 Robert C. Hewitt ’67 Ralph A. Hulseman ’80 Robert J. Kallal ’49 Eve J. Higginbotham-Williams ’75 Edward C. Hume ’83 Mauritz J. Kallerud ’62 Harold B. Higgins ’44 Albert S. Humphrey ’49 Elsa Kam-Lum ’74 Arthur E. Higinbotham ’60 Dean E. Humphrey ’49 Harold W. Kamins ’78 Arthur S. Hill ’63 Edwin P. Hunger ’54 Angelo W. Kandas ’93 Charles G. Hill Jr. ’59 Catherine M. Hunter ’81 Edward D. Kane ’47 Robert J. Hinds ’53 Jean B. Hunter ’76 Eugene W. Kane ’47 Thomas J. Hirasuna ’76 Julia A. Hunter ’84 Rahra Kang ’01 Peter M. Hirsch ’79 Gilbert L. Huppert ’89 Shin G. Kang ’91 Henry E. Hirschland ’49 Robert H. Hurt ’87 Amy B. Karger ’98 Sidney Hirshon ’37 Albert G. Hutchins III ’53 David A. Karohl ’85 Anthony W. Ho ’96 Daniel Hyman ’52 Daphne Karydas ’94 Henry Ho ’52 Brian Hynes ’95 Brian R. Kashiwagi ’64 Nancy M. Ho ’95 Tomoko Iida ’02 Stanley Kasper ’48 William Hoagland ’73 Kristin M. Imsande ’95 I. M. Kasser ’60 Robert M. Hodges ’60 Robert R. Imsande ’42 Stacy D. Katchman ’87 Allan S. Hoffman ’53 Paul P. Ip ’82 David A. Katz ’80 Thomas R. Hoffman ’87 Thomas B. Irwin ’80 Gerald Katz ’59 Thomas S. Hoffman ’56 Larry Z. Isaacson ’53 William E. Katz ’48 Wilburn H. Hoffman ’46 James J. Isenberg ’75 James R. Katzer ’70 John E. Hofmann ’56 Allan B. Isham ’56 Lara I. Kauchak ’96 Henry G. Hohorst ’52 Wesley J. Ishida ’84 Arnold F. Kaulakis ’38 Stanley E. Holbrook ’44 Shingo Ishikawa ’79 John D. Kavazanjian ’72 Stacy M. Holden ’00 Frank J. Iskra ’48 Herbert Kay ’47 Henry R. Holgate ’89 John M. Iwasyk ’60 Nancy D. Kayvanfar ’85 William D. Holland ’58 Kingsbury T. Jackson ’40 Marwan M. Kazimi ’96 Edward H. Hollister III ’50 Norman A. Jacobs ’59 Mitchell F. Keamy ’47 Charles R. Holman ’36 Ralph L. Jacobson ’35 Andrew H. Kean Jr. ’43 Geoffrey W. Holman ’80 Thomas A. Jadwin ’69 John R. Kearney ’48 Pamela L. Holmes ’92 Frederick L. Jaggi ’57 Tamara J. Kearney ’99 Benjamin M. Holt ’37 Hugh R. James ’74 James B. Keeler ’81 Robert P. Holton ’57 Peter A. James ’67 James J. Keenan ’48 Charles A. Homsy ’53 Vincent W. James ’78 George T. Keene ’52 Caroline C. Hon ’01 James M. Jamieson ’70 Caroline L. Keller ’97 Robert W. Hone ’79 Alice Jang ’00 George M. Keller ’48 Glenn T. Hong ’81 Christine J. Jang ’93 Michelle B. Keller ’84 Joonkee Hong ’84 Frederick J. Jao ’98 John S. Kellett ’47 Kristy H. Hong ’99 Lawrence A. Jarnagin ’58 Ralph L. Kelly Jr. ’42 Wan-Jen Hong ’01 Mottlene Jarvis ’74 Thomas K. Kelly ’44 Thomas Hooker ’40 George R. Jasny ’52 Kenneth Kelton ’49 John W. Hoopes Jr. ’44 Donald M. Jassowski ’57 Robert M. Kemper II ’65 Kenneth R. Hootnick ’61 Sarah E. Jatko ’98 Delbert W. Kendall ’24 Lloyd N. Hoover ’56 Alwyne C. Jealous ’42 C. T. Kennedy ’42 27 Colin J. Kerwin ’82 Louis F. Kreek ’48 Chung M. Lee ’87 David S. Keselica ’83 David W. Kress ’67 David S. S. Lee ’98 Donna L. Kessel ’89 Michael J. Kreuze ’93 Dek S. Lee ’80 Yehia F. Khalil ’86 John N. Krikelis ’97 George Lee ’52 Fadilah A. Khan ’02 Hannes B. Kristinsson ’51 Heather M. Lee ’95 Samer S. Khanachet ’72 Elizabeth J. Kroeker ’91 Helen H. Lee ’02 Bhupendra N. Khetani ’60 Adam D. Kroft ’00 Ivan H. Lee ’98 Donna M. Kilian ’80 Robin A. Krolikowski ’93 Jenny C. Lee ’96 Byung C. Kim ’58 Charles L. Kroll ’49 Jeong S. Lee ’80 Hose Kim ’81 Thomas P. Kronenberger ’88 Julian P. Lee ’97 In Ho H. Kim ’56 Dean E. Kross ’73 Kathy J. Lee ’99 Jeenok T. Kim ’84 John A. Krueger ’70 Lester A. Lee ’55 Joo C. Kim ’61 Richard T. Krueger ’48 Max N. Lee ’58 Juyong B. Kim ’00 Richard M. Kruger ’76 Richard Y. Lee ’97 Miral E. Kim-E ’85 Gilbert K. Krulee ’44 Robert Lee ’82 Robert M. Kimmel ’64 George C. Krusen ’50 Wanchieh Lee ’02 William O. Kincannon Jr. ’50 Larry J. Krussel ’73 Yam Y. Lee ’82 Cary J. King III ’58 Yuji Kubo ’01 Yung B. Lee ’81 Charles H. King Jr. ’41 Joseph D. Kuhach Jr. ’83 Ronald P. Leemhuis ’72 Robert C. King Jr. ’88 Alexander M. Kulinowski ’83 Steven J. Lefkowitz ’00 Terry S. King ’79 Dennis Y. Kuo ’84 Haiyun M. Lei ’00 George S. Kingsley ’83 Hirofumi Kurihara ’66 Jean P. Leinroth Jr. ’48 Erdogan Kiran ’69 Ronald T. Kurnik ’81 Joseph E. Leitgeb ’57 Kenneth A. Kirk ’81 Stuart J. Kurtz ’63 Frank B. Leitz Jr. ’55 Wylie C. Kirkpatrick ’40 Charles L. Kusik ’56 Robert B. Lennox ’83 Thomas P. Kisala ’85 Chi S. Kwan ’52 Stephen T. Lentz ’86 Linda D. Kiss ’87 Gerald K. Kwentus ’67 Katie M. Leo ’95 Robert D. Kiss ’87 Lily F. Kwok ’80 Edward F. Leonard ’53 Yves J. Kissenpfennig ’95 Agathagelos Kyrlidis ’89 Donato R. Leone ’59 William R. Kittredge ’43 William J. LaPoint Jr. ’84 Sai B. Leong ’80 Kazuo Kiyonaga ’50 Aaron J. Labrocca ’98 Sing Leong ’45 Katherine M. Klar ’97 Arthur J. Lacroix ’45 Richard N. Leslie ’66 Mitchell Klausner ’84 Arthur P. Lagace ’60 Gerald A. Lessells ’50 Howard W. Klee Jr. ’72 James Lago ’47 James C. Leung ’75 Gary G. Klein ’74 Chiu-Kin S. Lai ’86 James A. Levitan ’45 Max M. Klein ’81 Chung J. Lai ’73 Roy N. Levitch ’66 Wm. S. Kleinman ’79 Robert I. Lait ’54 Karl B. Levy ’83 David E. Kleinschmidt ’76 David S. Laity ’50 Peter F. Levy ’79 Hans A. Klemm ’75 Frederick W. Lam ’89 Philip C. Lewellen ’75 Allen L. Klibanoff ’56 Harry W. Lambe ’49 Natalie D. Lewis ’86 Douglas F. Kline ’93 Paul E. Lambert ’63 Peter J. Lewis ’65 David H. Klipstein ’56 Gerard C. Lammers ’48 Robert W. Lewis ’61 Norman R. Klivans ’40 Steven P. Lamontagne ’01 George T. Li ’89 Stuart R. Knapp ’31 Ralph Landau ’41 Marlene M. Li ’89 Chester E. Knight Jr. ’64 Robert E. Lander ’52 Yulan Liao ’96 Joseph K. Knight ’40 Mary E. Landrum ’87 James W. Libby Jr. ’35 Heather L. Knoedler ’94 J. H. Laning ’40 Frank H. Libman ’40 John A. Knowlton Jr. ’49 Teresa S. Lantz ’82 William R. Licht ’87 David H. Koch ’62 Berton M. Lapidus ’59 William E. Lifson ’41 Robert W. Koch ’50 Ana I. Laplaza ’94 Bruce D. Lilly ’93 Wendy S. Koegler ’00 Cheryl A. Larrivee-Elkins ’87 Larry J. Lilly ’65 Kenneth C. Koehlert ’83 Howland A. Larsen ’50 Fredric J. Lim ’83 Han-Jong Koh ’86 Jason K. Larsen ’99 Kenneth J. Lim ’70 Henry H. Kohl ’48 Paul R. Larson ’54 Kirk W. Limbach ’89 Alison D. Kohler ’78 Albert K. Lau ’72 Danielle J. Lin ’98 Edward Kohler ’95 Edmund K. Lau ’75 David Y. Lin ’98 Jo-Anne M. Kokoski ’96 Amy B. Laverdiere ’99 George F. Lin ’98 Frederick J. Kolb Jr. ’38 Hugh P. Lavery ’73 Nelson P. Lin ’91 James D. Kolb ’53 Stephen D. Laveson ’60 Selina Lin ’84 Paul C. Kolosick ’86 James S. Law ’72 Wendy W. Lin ’84 Sheila J. Konecke ’80 John V. Lawler ’86 John W. Lincoln ’55 Amy K. Koo ’95 Michelle Lawlor ’97 Carl A. Lindstrom ’49 Harry L. Kopp ’48 Evan K. Lawrence ’50 William Lintner Jr. ’53 Paul M. Koppel ’54 Leroy E. Layton ’50 John R. Linton ’84 Kenneth D. Kopple ’51 Melanie L. Lazaro Flores ’92 W. H. Linton Jr. ’47 Ernest I. Korchak ’61 Francis N. Le Baron ’44 Malcolm J. Lipson ’50 Theodore H. Korelitz ’56 Jeffrey B. LeBlanc ’98 Theresa M. Liu ’97 Michael A. Kornitzky ’62 Shirley C. LeMay ’89 Fred P. Lobban ’40 Richard G. Kotosky ’81 Steven R. LeMott ’72 Paul A. Lobo ’50 Robert W. Koucky ’56 Donald C. Lea ’50 Raymond S. Locatelli ’65 Alexandros Koulouris ’91 Kathleen J. Leach ’92 George O. Lof ’40 Kenneth L. Kovach ’83 James W. Leader ’43 Jordan Loftus ’50 Eugene J. Kovary ’54 Andrew W. Lee ’76 Robert C. Lonadier ’84 Robert F. Kratz ’44 Barbara A. Lee ’87 William C. Long ’59 Lawrence R. Kravitz ’60 Chun-Hyuk Lee ’94 Joseph V. Longcor ’38 28 John M. Longoria ’86 John V. Maxham ’69 Leon Mir ’61 John P. Longwell ’43 Jerome F. Mayer ’74 Floro D. Miraldi ’53 Emilio M. Lopez ’87 Siegfried T. Mayr ’70 Mary Beth E. Miranda ’88 Juan M. Lopez ’79 George C. Mc Farland ’24 Richard T. Miskinis ’53 Daniel F. Lord ’44 Guy T. McBride Jr. ’48 Angela M. Mislowsky ’99 Rebecca E. Lords ’89 James K. McCauley ’51 Lisa Misterka-Benati ’91 Richard A. Loring ’62 Hugh E. McCollum ’65 Robert L. Mitchell Jr. ’43 Jeremiah A. Lott ’48 Douglas D. McConnell Jr. ’42 Samuel L. Mitchell ’52 Otway Louie ’93 Kenneth H. McCorkle Jr. ’51 William J. Mitchell ’53 Quintin B. Louie ’01 Donald C. McCulloch ’63 Thomas W. Mix ’56 Bertrand C. Louvet ’62 Charles W. McCutchen ’49 Wang-Tsee T. Mo ’88 Richard N. Lovett ’43 Crawford McDonald ’48 Wm. D. Mohr ’50 Robert F. Lovezzola ’48 Howard M. McDowell ’60 Lingfung Mok ’80 John M. Luger ’51 Lindsay J. McFadden ’96 Brian V. Mokler ’60 Robert M. Lurie ’52 Robert G. McGrath ’53 Alexandra N. Molnar ’02 Martiel A. Luther ’82 John D. McGrew ’51 Aaron J. Moment ’96 Christine M. Lyons ’86 Joseph R. McHugh ’42 Charles W. Monroe ’55 Michael J. Lysaght ’64 Robert A. McIlroy ’58 Craig C. Monsell ’77 Yi H. Ma ’67 Robert V. McIntyre ’98 Jose H. Montero ’83 Alan L. MacLean ’44 David McKay ’43 Timothy L. Montgomery ’74 Marc Machbitz ’78 Richard G. McKee ’54 Steven S. Moor ’77 Anthony C. Mack ’62 John T. McKenna Jr. ’50 Albert L. Moore ’58 Arnold Mackintosh ’44 Richard C. McKern ’94 Arthur W. Moore ’59 Temina C. Madon ’98 Julian T. McKinnon Jr. ’89 James W. Moore ’78 Robert P. Madrulli ’51 Mary A. McLaughlin ’58 Joe F. Moore ’52 Robert D. Maher ’44 Gerald S. McMahon ’36 Allan C. Morgan ’60 Louis E. Mahoney III ’54 Lee P. McMaster ’69 Dale F. Morgan ’38 William F. Mahoney ’89 James D. McMillan ’90 Dean T. Morgan ’57 Thomas O. Maier ’67 Robert L. McMurtrie ’52 Hans G. Morgenstern ’58 Donald A. Mains ’47 James B. McNeely ’57 John H. Morgenthaler ’51 Alex S. Malaspina ’52 James D. McNitt ’41 Edward G. Morin ’39 Jeffrey K. Malcolm ’98 Bryant R. Mclaughlin ’00 Brian R. Moroney ’82 Gregory S. Malkin ’76 John J. Mealy ’51 Eric M. Morrel ’87 Francis M. Mallee ’74 Max F. Means ’48 Stephen R. Morris ’82 James A. Malloch ’43 Hendrik J. Meerman ’84 William C. Morris ’60 John B. Malloy ’50 Neville Z. Mehenti ’01 Beverly A. Morrow ’73 Robert L. Malster ’56 Jerome F. Meier ’89 George M. Morrow III ’41 David A. Manalan ’65 Herbert J. Meiselman ’66 David C. Morse ’56 Gerald Mandel ’77 Edward O. Meisner ’47 Merton Morse ’51 James L. Manganaro ’61 Jerry H. Meldon ’73 Peter C. Moss ’59 Ivan Mankowich ’33 Peter Melnik ’52 Johnson Mossman ’50 Albert R. Manner ’79 Marco A. Mena ’99 John A. Moulson ’62 Brian A. Mannion ’84 Robert B. Meny ’44 David T. Moyle ’94 Rodney C. Marable ’01 Akbar A. Merchant ’89 Joan T. Muellerleile ’85 Frank A. March ’67 Peter B. Merkle ’84 Debi P. Mukherjee ’69 James K. Marchetti ’96 Edward W. Merrill ’47 Antonio Mulet ’80 Jan W. Mares ’60 Noelle M. Merritt ’85 James A. Mulholland ’58 Stanley V. Margolin ’49 Richard T. Merritt ’42 Lorenz A. Muller ’87 Geoffrey Margolis ’69 Arthur B. Metzner ’51 Allan U. Munck ’48 Mark E. Marinan ’81 Juan M. Meyer ’68 Paul S. Munn ’46 Charles P. Marion ’52 Robert E. Meyer ’46 Richard L. Murdock ’58 Amy L. Markel ’85 Amy S. Meyers ’89 Charles F. Murphy ’51 Alan B. Marks ’70 Stephen L. Michaels ’76 Regina M. Murphy ’78 Jerold S. Marks ’79 Laurent P. Michel ’47 Stephen F. Murphy ’87 Stanley Marple Jr. ’41 Richard C. Michel ’75 Thomas P. Murphy ’54 Andre V. Marrou ’62 Robert C. Michel ’50 Gilman Y. Murray ’44 Henry N. Marsh ’51 Stephen S. Mickel ’80 Robert M. Murray ’48 Courtenay D. Marshall ’33 Harold S. Mickley ’46 William M. Murray Jr. ’55 Harry A. Marshall ’65 Richard G. Miekka ’58 Stephen A. Murtha ’74 Mark E. Marshall ’80 Theodoros G. Mihopoulos ’94 Kevin T. Musselwhite ’99 John E. Marsland Jr. ’57 Glen A. Miles ’59 Michael Mutsakis ’72 Geo H. Martin ’53 Irwin W. Millen ’50 David F. Myers ’81 Jeffrey W. Martin ’97 David R. Miller ’48 Henry J. Myers ’53 Reynold W. Martin II ’68 Deanna C. Miller ’83 Kenneth L. Myers ’98 Agustin Martinez ’95 James A. Miller ’50 Edward M. Myskowski ’62 Boni P. Martinez ’46 James D. Miller ’62 Mark R. Naber ’80 Wade S. Martinson ’00 Kimberley R. Miller ’83 Gerald J. Nacamuli ’67 Joseph B. Marx ’37 Stephen J. Miller ’48 Fred S. Nadel ’58 Ben Y. Mason ’44 Wayne E. Miller ’44 Divya J. Nagri ’98 Edward A. Mason ’50 William H. Millick III ’49 Paul R. Nahass ’83 Thomas A. Massaro ’63 Clare L. Milton ’40 Gabriel H. Nahigian ’96 John L. Mattana ’51 Sherrill L. Minch ’90 Stacey T. Nakamura ’80 Christian J. Matthew ’43 Carl S. Minden ’47 Rita Nanda ’93 John W. Matthews ’44 David R. Ming ’85 Michael J. Nash ’59 David J. Mawer ’62 Mark A. Mintun ’77 Walter C. Nason Jr. ’45 29 Angela R. Neale ’97 Richard D. Packard Sr. ’51 Paal Prestegaard ’61 Adonis A. Neblett ’79 George W. Page Jr. ’78 John L. Preston Jr. ’68 Lita L. Nelsen ’64 Philip F. Palmedo ’61 Jason D. Pride ’97 Eric D. Nelson ’98 Louis C. Palmer ’50 John J. Prior ’97 Lisette L. Nenninger ’90 Nicole A. Palmer ’02 David N. Prugh ’82 Noble M. Nerheim ’61 Tuomas A. Paloposki ’88 James M. Prusko ’86 Michael A. Neschleba ’69 Mark A. Panarusky ’85 Douglas A. Prybylowski ’83 Paul H. Netherwood ’33 Neil A. Panzier ’52 Andrzej B. Przedpelski ’46 Christine M. Neumann ’00 Theodore G. Papastavros ’55 John C. Putman Jr. ’47 George W. Neuner ’66 Chandrasekar Papudesu ’98 George C. Putnam ’36 Joseph P. Neville ’56 Trueman D. Parish ’63 Gordon B. Pye ’55 Barry A. Newman ’79 Chan D. Park ’75 Annemarie L. Quaadgras ’85 Margo L. Newman ’75 Keum J. Park ’93 H. M. Quackenbos ’41 Robert W. Newman ’36 Reginald Parker ’92 Richard J. Quann ’82 Andrew S. Ng ’73 Rienzi B. Parker Jr. ’59 Robert H. Quick ’53 Christine S. Ng ’97 Leonard J. Parsons ’64 Janet A. Quirey ’78 Hau Yee Ng-Lo ’84 John S. Paschkewitz ’95 Waqar R. Qureshi ’90 Shih-Tung Ngiam ’91 Stephen H. Pasternak ’87 Henry H. Rachford Jr. ’50 Davidhuy N. Nguyen ’02 Chandra Patel ’94 Frederick A. Radville ’48 Tuan Nguyen-Duy ’78 Bernard J. Patnode ’56 Sang-Chun Rah ’84 Hong Bin Ni ’92 Jennie R. Patrick ’79 Reza S. Rahaman ’89 William B. Nichols ’50 Richard S. Paul ’52 William P. Raiford ’89 Edward W. Nicholson ’36 Houston K. Payne ’56 Dilip Rajagopalan ’91 William J. Nicholson ’60 Donald W. Peaceman ’51 Julie A. Rakestraw ’90 Kenneth R. Nickerson ’58 William E. Peak ’74 Scott L. Rakestraw ’90 David E. Nickles ’62 Frank G. Pearce ’46 Carlos A. Ramfrez ’79 Christopher T. Nidel ’95 Jorge A. Pefaure ’76 David M. Ramirez ’93 Matthew E. Nilsson ’01 Abigail H. Pelcyger ’01 Alonso R. Ramos Vaca ’78 Reynold B. Nippe Sr. ’56 Wardner G. Penberthy ’81 George A. Randall ’66 Kemal M. Nisancioglu ’68 William B. Penn ’37 Kendall B. Randolph ’56 Tuknekah M. Noble ’99 Miguel Perales ’93 Betty R. Ransohoff ’84 Susan C. Noe ’87 Roger C. Perkins ’85 Thomas C. Ransohoff ’84 James P. Nolan Jr. ’51 Samuel E. Perkins II ’50 Mark J. Rapacioli ’87 Anthony R. Nole ’96 George P. Perkinson ’65 Maggie A. Raphael ’96 Ronald A. Norelli ’67 Christopher R. Perley ’77 William J. Rapoport ’46 Edward M. Norin ’68 Charles W. Perry ’35 Elta C. Ratliff ’94 Robert G. Norton ’51 Christopher D. Perry ’98 Gerald S. Rau ’83 Verrill M. Norwood Jr. ’53 Steven D. Perry ’87 Carl W. Rausch ’74 Richard M. Novo ’82 Rolph A. Person ’52 Lori A. Ray ’93 James P. Noyes ’53 David F. Petherbridge ’67 Martin L. Ray ’46 Amechi E. Nwachuku ’95 Kavas N. Petigara ’72 Willis B. Reals ’47 Catherine Nyarady ’93 Robert P. Petrich ’63 Stephen A. Reber ’75 David C. O’Brien ’53 Brian D. Phenix ’98 William H. Redlien Jr. ’46 John B. O’Brien ’64 Philip J. Philliou Sr.. ’55 Jefferson M. Reece ’68 Ellen M. O’Connell ’90 John J. Phillips Jr. ’38 Carleton M. Reed ’70 John P. O’Connell ’61 Oliverio Phillips-Michelsen ’48 Charles E. Reed ’37 Robert J. O’Donnell ’46 Wallace C. Philoon Jr. ’47 Charles L. Reed ’61 Analeah O’Neill ’00 Donald L. Phipps Jr. ’61 David W. Reed ’61 William O. O’Neill ’43 David G. Pickering ’85 Stanley D. Reed ’74 Jeffrey C. Oehler ’81 Rudolph W. Pierce ’50 William A. Reed ’43 Mary C. Oehler ’82 Thomas H. Pigford ’48 Winthrop B. Reed ’39 Paul D. Ogagan ’98 John J. Piret ’85 John H. Rees ’47 Larry M. Ogden ’58 John S. Pitcher ’87 Carolyn A. Reeves Saarinen ’86 Edwin M. Oh ’84 James A. Pitcock ’51 Suresh Reginald ’87 David T. Okamoto ’85 Sharon E. Plon ’79 Aaron P. Reichl ’96 Donald R. Olander ’58 Dirk A. Plummer ’52 Peter M. Reilly ’80 Jessica R. Oleson ’96 Jason W. Politi ’98 Ronald A. Reimer ’69 James D. Oliver ’81 John G. Polk ’53 Eric S. Reiner ’83 Robert C. Oliver ’53 Michael J. Pomianek ’90 Ralph I. Reis ’48 James M. Olivo ’82 Arturo Ponce Alcala ’47 Edward G. Remmers ’52 Sven A. Olund ’51 Brian W. Pontius ’83 Laura L. Renninger ’97 Lillian M. Oppenheimer ’83 Olapeju A. Popoola ’96 Todd M. Renshaw ’87 Robert D. Orlandi ’74 Jill E. Porter ’85 Timothy J. Resch ’95 William F. Orr ’41 Neil S. Portnoff ’73 Hyman Resnick ’49 Ronald G. Ort ’71 Jane H. Potter ’80 Richard H. Reuther ’51 David E. Ortman ’79 J. L. Powell ’47 Conrad S. Revak ’58 Joseph F. Osha ’62 Kevin T. Powell ’89 Albert B. Reynolds ’53 Martine M. Osias ’90 Robert W. Powell ’70 Judson C. Rhode ’40 Mark I. Ostler ’69 Arthur J. Power ’42 Frank J. Rhodes ’81 Steven G. Oston ’59 Sutikshan Prakash ’65 Harold A. Ricards Jr. ’41 Ravinder K. Oswal ’80 Kristala J. Prather ’94 James W. Rice ’57 Jeffrey Ou ’94 Mark R. Pratt ’60 William L. Rice ’53 Alfred J. Oxenham ’45 Randall N. Pratt ’44 Edwin T. Richard ’51 Rudolph J. Ozol ’36 Stuart W. Pratt Jr. ’51 David M. Richards ’86 Walter J. Paciorek Jr. ’65 Anthony Praznik ’56 Robert J. Richardson ’54 30 William S. Richardson ’44 David S. Sabo ’61 Howard E. Schwiebert ’40 Royal C. Riedinger ’54 Toby R. Sachen ’78 Chris E. Schwier ’84 Herbert Riegel ’49 Robert B. Sackheim ’39 Arthur D. Schwope ’72 John E. Riley ’39 Shafik E. Sadek ’66 Steven F. Sciamanna ’81 Lynn C. Riley ’84 Martin J. Sadofsky ’78 Edwin A. Scott Jr. ’48 Auguste E. Rimpel Jr. ’60 Connie M. Sadowski ’99 Jocelyn E. Scott ’84 Peter M. Rinaldo ’44 Robert F. Sadowski ’50 Stewart Scott III ’50 Irven H. Rinard ’57 Stanley J. Sadowski ’53 Eugene Scoville ’78 Alvin E. Ring ’48 Tracy M. Sadowski ’99 Bruce E. Scruggs ’88 Jose A. Rionda Jr. ’62 Basil C. Safos ’80 Robert N. Secord ’42 James B. Risser ’57 Hiroshi H. Saito ’91 Leonard A. Seder ’37 Kimberly E. Ritrievi ’85 Jeffrey B. Sakaguchi ’82 Andrew Seidenfeld ’68 John E. Ritter ’82 Glen N. Sakima ’83 George R. Seiler ’57 Ricardo C. Rizo-Patron ’79 Shelly E. Sakiyama-Elbert ’96 William A. Selke ’43 Lester E. Robb ’47 Morris Salame ’60 Charles W. Selvidge ’63 James D. Roberge ’84 Todd R. Salamon ’96 Suren A. Semonian ’50 John H. Roberts ’56 Norman I. Salas ’69 Michael A. Serio ’84 Cynthia S. Robertson ’55 Miren C. Salsamendi ’82 James Seth ’36 Geoffrey Robillard ’44 Frank Salz ’57 William R. Seuren ’47 Norman A. Robins ’55 Dominick A. Sama ’54 Stephen D. Severson ’76 John M. Robinson ’81 Rafael Sanabria ’79 Lawrence R. Sewell ’72 John M. Roblin ’55 Gilbert W. Sanchez ’75 John D. Sewer ’00 Stanley B. Roboff ’43 Robert L. Sandel ’64 Ray W. Shade ’49 Richard K. Rockstroh ’50 Harish N. Sangani ’86 Mona K. Shah ’00 Avital A. Rodal ’97 John T. Santini ’99 Pauravi M. Shah ’02 Otha C. Roddey ’51 Salvatore L. Santo ’51 Rajendra Y. Shah ’74 Phyllis W. Rodriguez ’00 Behrooz Satvat ’80 Paul M. Shain ’81 Theodore B. Roessel ’44 Gerald K. Saul ’57 William S. Shamban ’38 Bethany M. Rogers ’97 Deborah E. Savage ’92 John C. Shambaugh ’61 Joseph E. Rogers ’73 Edward E. Savard ’87 Erica S. Shane ’86 Reginald E. Rogers Jr. ’01 Raymond M. Sawka ’91 Frank G. Shanklin ’52 Edward Rolfe ’51 Craig D. Sawyer ’60 Jennifer R. Shapiro ’01 R. J. Rollbuhler ’54 Clifford M. Sayre Jr. ’52 Paul S. Shapiro ’63 Florence R. Rolston ’88 Edgar M. Scattergood ’58 Stephen I. Shapiro ’66 Philip B. Romanik ’82 Kirk D. Scattergood ’79 Alfred C. Sharon ’76 Michael J. Romney ’66 Eugene J. Schaefer ’85 Deborah S. Sharpe ’76 Douglass E. Root Jr. ’44 Daniel M. Schaeffer ’42 Robert G. Shaver ’52 Thatcher W. Root ’79 Albert R. Schallenmuller ’56 James F. Sheehan Jr. ’48 Robert L. Rorschach ’43 Walter S. Scheib Jr. ’52 Linda M. Sheehan ’85 Stephen H. Rose ’71 George F. Schlaudecker ’39 Seymour J. Sheinkopf ’39 David Rosen ’58 Robert L. Schlegel ’59 Jack L. Shelton ’58 Martin N. Rosen ’62 Mark J. Schmaier ’82 Emil W. Shen ’78 H. J. Rosenberg ’45 Frank G. Schmaltz Jr. ’59 Yen Shen ’42 Robert E. Rosenberger ’67 Michael R. Schmid ’57 Norman F. Sheppard Jr. ’78 Barnet L. Rosenthal ’30 Frederick W. Schmidt ’61 John D. Sherman ’66 Murray W. Rosenthal ’53 John P. Schmidt ’63 Albert E. Sherwood ’52 Richard S. Rosera ’70 Hanno K. Schmidt-Gothan ’90 Lynn Shi ’00 Alexander G. Ross ’61 William J. Schmitt ’85 Shuaichen S. Shi ’97 Frederick J. Ross ’46 George A. Schnabel ’60 John W. Shield ’89 John M. Ross ’56 Caspar C. Schneider Jr. ’44 Ashley K. Shih ’91 John R. Ross ’67 Dean A. Schneider ’69 Paul J. Shim ’84 Joel N. Rossen ’48 George R. Schneider ’56 Hyunkook Shin ’62 Philip M. Roth ’60 Gia D. Schneider ’99 Annette D. Shine ’83 Stan R. Roth ’75 S. B. Schneiderman ’58 Gregory B. Shinn ’84 Burton M. Rothleder ’53 Carol A. Schnepper ’84 Duane E. Shinnick ’70 Paul H. Rothschild ’58 Leonard J. Schnetzer Jr. ’59 Lloyd G. Shore ’41 Margaret H. Rousseau ’37 Fritz Schnorf ’52 Adam L. Shrier ’60 William C. Rousseau ’36 Bern J. Schnyder ’60 Joseph Shrier ’44 Robert J. Roy ’82 David E. Schoeffel ’51 Ruchi Shrivastava ’01 Stephen J. Rozendaal ’49 Cassandra S. Schoessow ’99 Kenneth R. Sidman ’67 David B. Rubin ’75 James E. Schonblom ’56 Donald H. Siefkes ’64 Loring W. Rue Jr. ’53 Robert J. Schrader ’43 Robert E. Siegfried ’47 Frank E. Rush Jr. ’44 Gerald L. Schroeder ’59 William L. Sifleet ’75 Allen P. Russell ’82 Dale S. Schultz ’84 Charles A. Siletti ’89 Charles D. Russell ’57 Theodore F. Schultz ’59 Jeffrey E. Silliman ’72 Morley E. Russell ’53 Barbara J. Schultze ’02 Ronald A. Sills ’70 Leonard W. Russum ’47 Robert B. Schulz ’79 Richard S. Silver ’63 Christian L. Rust ’51 Stephen R. Schulze ’66 Peter M. Silverberg ’60 Gregory C. Rutledge ’90 Carl P. Schumacher ’51 David C. Silverman ’69 Philip A. Ruziska ’62 Arthur Schwartz ’47 Harsono S. Simka ’98 James Ryan ’51 J. E. Schwartz ’52 John A. Simmons ’53 Lisa M. Ryan ’81 Eric G. Schwarz ’53 Irwin B. Simon ’68 Arthur R. Ryrholm ’46 Hugh W. Schwarz ’42 Valeria M. Simone ’97 Dewey D. Ryu ’61 Richard W. Schweizer ’50 Vinson R. Simpson ’50 Fouad P. Saad ’95 Daniel M. Schwendenman ’83 James A. Sinclair ’64 31 Jean E. Singer ’79 John E. Stauffer ’57 Thomas R. Taylor ’38 Marvin I. Singer ’63 David K. Steckler ’87 James H. TeStrake ’62 Paul A. Siock Jr. ’65 Robert A. Steel ’38 Catherine E. Teague Sigal ’81 Arthur L. Sirkin ’56 Olaf Steen Jr. ’50 Michael E. Teixeira ’88 Ricardo Sitchin ’80 Edward R. Stefaniak ’51 Donato R. Telesca ’48 Hoi Man Siu ’87 Nelson E. Stefany ’61 Leonard R. Tenner ’60 Nicole M. Skaf ’97 Robert K. Steidlitz ’79 Evan W. Thayer ’91 George T. Skaperdas ’38 Harold A. Stein ’56 Robert V. Thiede ’44 Richard E. Skavdahl ’56 Robert M. Steinberg ’81 Edward F. Thode ’42 Benjamin L. Skinner ’42 Don Steiner ’60 Edward T. Thompson ’49 Carl P. Slenk ’56 Peter L. Steinhagen ’79 Keith M. Thompson ’64 John E. Slifer ’44 Reed C. Steinmetz ’87 Louis S. Thompson ’63 Robert L. Slifer ’50 Harvey G. Stenger Jr. ’84 R. R. Thompson ’61 Melvin R. Sline ’69 David Stern ’79 Suzanne M. Thompson ’81 Bernard Slosberg ’63 Howard S. Stern ’53 Robert T. Thomson ’84 Robert S. Slott ’58 Robert L. Stern ’48 Ellen A. Thorne Lane ’88 Robert P. Slusser ’47 William R. Stern ’40 Barbara A. Thornton ’77 Jan K. Smeets ’71 Robert V. Sternberg ’39 Kathrine R. Threefoot ’84 Amy A. Smiley ’84 Bruce W. Stevens ’64 George M. Thurlow ’54 Brian R. Smiley ’83 Douglas M. Stevens ’83 Jean Tilly ’83 Alan T. Smith ’53 Robert L. Stevens ’49 William J. Timson ’50 Douglas S. Smith ’86 William B. Stevenson ’35 Robert Tischbein ’38 Frank G. Smith ’81 Mark W. Stewart ’98 Elaine R. Tobias ’79 Frederick C. Smith ’43 Warren E. Stewart ’51 Jeanne E. Tomaszewski ’00 George C. Smith Jr. ’49 Kenneth W. Stickney ’48 Hsueh-Rong Tong ’81 Joe M. Smith ’43 Ted J. Stoecker ’82 John F. Tormey ’43 Kenneth A. Smith ’58 Thomas J. Stohlman Jr. ’76 Jose V. Tormo ’81 Louis C. Smith ’36 Bayard T. Storey ’55 Edward C. Torres ’93 Michael J. Smith ’59 Richard A. Strauss ’60 Juan E. Torres ’82 Robert F. Smith ’58 Justin A. Strittmatter ’95 Luisa K. Torrielli ’98 Robert S. Smith ’47 Pieter Stroeve ’73 Warren L. Towle ’34 Toussaint Smith ’89 Robert J. Struble ’85 Robert W. Townsend ’48 Stanley C. Smock Jr. ’44 Nathan v Stuart ’92 Robert M. Train ’75 Robert A. Snedeker ’50 Harold A. Stubing ’55 Richard T. Traskos ’66 Steven J. Snider ’82 Michael C. Sudol Jr. ’58 Harvey C. Travers ’49 Jeffrey P. Snow ’78 Tzeng J. Suen ’35 David R. Treadwell ’33 Michael J. Snow ’86 Sarosh P. Sukhia ’66 David P. Trempel ’85 Richard A. Snow ’48 Thomas E. Sullivan ’40 Charles A. Trilling ’49 Jay E. Sobel ’61 William H. Sun ’79 Sergio C. Trindade ’73 Charles R. Solenberger ’57 Cynthia Sung ’89 Edwin P. Tripp III ’67 Janet A. Sollod ’96 Wei F. Sung ’77 Richard H. Tromel ’58 Daniel I. Solomon ’82 David C. Surber ’82 Robert J. Tronnier ’73 George S. Somekh ’56 Harry D. Surline ’64 Martin J. Troster ’51 Steven R. Sommer ’77 Norman F. Surprenant ’49 Theodore D. Trowbridge ’59 Maria R. Sondhaus ’87 Akira Suzuki ’63 George A. Truskey ’85 Yihhong L. Song ’78 Jahnavi Swamy ’95 Mun C. Tsang ’79 Scott G. Sontheimer ’84 David E. Swanberg ’40 Wing Tsang ’56 Jasjeet S. Sood ’80 David S. Swanson ’53 Mosum E. Tsui ’82 Patrick S. Spangler ’60 Dennis V. Swanson ’68 Tsu-Man P. Tu ’86 Kevin A. Sparks ’91 James R. Swartz ’78 Edward L. Tucker ’61 Gordon D. Specht ’54 Jeanne L. Swecker ’83 W H. Tucker ’46 Herschel Specter ’57 George C. Sweeney Jr. ’47 Glenn A. Tuckman ’77 Karen Y. Spencer ’86 Linda E. Sweeney ’83 Antonio Tuells Juan ’65 Barry M. Speyer ’61 Maxwell P. Sweeney ’50 Lisa A. Tung ’88 Stephen H. Spiegelberg ’93 Darius Sweet ’81 Shao E. Tung ’54 Peter H. Spitz ’48 Robert F. Sykes ’44 Howard T. Tupper ’52 Thomas M. Spitznagel ’88 Wendell G. Sykes ’50 Seymour B. Turetzky ’61 Herbert L. Spivack ’49 Min-Nan Sze ’70 Frederica C. Turner ’95 Joia K. Spooner-Wyman ’01 Morgan C. Sze ’39 Lawrence C. Turnock ’41 Kimberley J. Sprague ’83 Andrea M. Tabor ’82 Robert S. Tutunjian ’72 Dennis L. Sprecher ’74 William Taggart ’59 Herbert G. Twaddle ’43 Katherine A. Squire ’97 Raj V. Tahil ’81 Chaplin Tyler ’23 Arthur L. Squyres ’53 Hsin-Chien Tai ’93 Nkereuwem I. Udofia ’83 Manakan B. Srichai ’94 Luther Tai ’70 Page S. Ufford Jr. ’44 Kevin E. St Onge ’85 Robert W. Tait ’80 John C. Uhrmacher ’64 Thomas M. St. Louis ’85 Kudzaishe G. Takavarasha ’99 John G. Ullman ’47 Richard L. Stadterman ’75 Richard E. Talmadge ’54 Christina C. Um ’00 James J. Staikos ’50 Kiichiro Tanabe ’61 Jacqueline T. Underberg ’01 Jeffrey D. Stamler ’00 Jack C. Tang ’49 Kevin D. Uptain ’99 Arnold F. Stancell ’62 Frank A. Tapparo ’60 Angela L. Urdanoff ’82 Michael D. Stanfield ’53 Oded Tavory ’51 Debra A. Utko ’80 Robert B. Stanfield ’57 Sew-Wah Tay ’86 David H. Vahlsing ’58 Walter T. Stanley ’75 Douglas J. Taylor ’39 Jaime A. Valencia-Chavez ’78 Louis E. Stark ’47 Harry C. Taylor ’54 Marketa Valterova ’00 Anthony Stathoplos ’51 Joshua D. Taylor ’98 Walter L. Van Nostrand Jr. ’50 32 William T. van Ravenswaay ’44 Abraham Weitzberg ’57 Walter F. Worth ’68 William D. Van Vorst ’43 Jeffrey P. Welch ’91 David A. Wright ’90 Jon Van Winkle ’53 Martin A. Welt ’57 Edward E. Wright Jr. ’58 Arthur P. Vasen ’83 Ralph L. Wentworth ’48 Wesley Wright Jr. ’57 Steven N. Vaslef ’80 Jason A. Wertheim ’96 Donna T. Wrublewski ’00 Ferdinand S. Veith ’47 Jennifer L. West ’92 Ching-Shiun Wu ’78 Dell F. Venarde ’55 Jessica L. West ’98 Mario R. Wunderlich ’45 David P. Ventola ’91 Theresa A. Weston ’80 Richard A. Wuopio ’60 Frank J. Venuti ’74 Otto K. Wetzel ’48 Larkin T. Wyers Jr. ’43 Michele C. Verticchio ’02 Lennard Wharton ’55 George M. Wyman ’62 Nancy P. Vespoli ’79 Philip M. Wheaton ’82 Liangzhi Xie ’97 Gerard F. Vetromile ’63 Michael P. Whelan ’80 Ye Xu ’99 Vincent L. Vilker ’76 Nicholas H. Wheless Jr. ’38 Vijay M. Yabannavar ’88 Philippe G. Vilmorin ’02 William B. Whiston ’51 Dennis D. Yancey Jr. ’98 Susan A. Visser ’86 Chiquita V. White ’85 Linda Yang ’85 Chitra Viswanathan ’95 William P. White ’64 Ioannis V. Yannas ’59 Valerie J. Vitale ’81 Lawson E. Whitesides Jr. ’71 Bruce S. Yarmoska ’79 Henry C. Vogel ’41 Alfred Whitman ’50 Michael J. Yaszemski ’95 David E. Voit ’68 Roy P. Whitney ’35 St Clair P. Yates ’38 Kathleen G. Vokes ’00 Richard H. Wick ’58 Chiann J. Yeh ’96 David Volfson ’85 David A. Wickham ’84 Por-Wun Yeh ’84 Robert L. Von Berg ’44 Carl V. Wikstrom ’90 I-Kuen Yen ’56 George F. Von Fuchs ’59 Christina M. Wilbert ’01 Pao M. Yen ’44 John C. Vyverberg Jr. ’39 David S. Wilbourn ’55 Stephen J. Yeretsky ’59 David L. Wagger ’92 Richard J. Wilcox ’85 Johnny C. Yeung ’77 William H. Waite ’30 Ross P. Wilcox ’77 Reginald S. Yeung ’59 Zwi H. Waldman ’57 John A. Wilkens ’77 Jim C. Yin ’85 Raymond J. Waldmann ’60 Lucile S. Wilkens ’77 Jessica Y. Yip ’02 Charles M. Walker ’49 John A. Willard Jr. ’50 John E. Yocom ’47 William W. Walker Jr. ’70 Laura B. Willett ’79 Mark I. Yogman ’66 Jesse T. Wallace ’58 Corrine M. Williams ’01 John R. Young ’48 Robert R. Walsh ’85 Curtis C. Williams III ’50 Kai W. Young ’58 Albert E. Walz Jr. ’54 James E. Williams ’81 Richard E. Young ’56 Hans G. Walz ’43 Peter M. Williams ’57 Charles R. Youngson Jr. ’72 Eva C. Wan ’81 Pyam W. Williams ’36 Adrian P. Yovanovich ’83 Mona M. Wan ’84 W. G. Williams ’68 Stephen K. Yu ’80 Stephen S. Wan ’82 David V. Williamson ’53 Wendy H. Yuan ’80 Albert Y. Wang ’85 David A. Willis ’60 William W. Yuan ’59 Beatrice Wang ’99 Gary N. Willson ’85 Pak K. Yuet ’96 Daniel I. Wang ’59 R. S. Wilson ’80 Alan Yung ’78 Dean C. Wang ’95 Robert E. Wilson ’50 Russell E. Zagrodzky ’61 Lawrence C. Wang ’84 Steven R. Wilson ’75 Aina Zahari ’02 Mei-Hui Wang ’86 Todd D. Wilson ’88 Joseph G. Zahka ’71 Peggy J. Wang ’02 Eugene B. Wilusz ’68 Domenic A. Zambuto ’85 Richard D. Wang ’78 Leonard Wimpfheimer ’54 Howard B. Zasloff ’52 Kenneth L. Warden Jr. ’43 Max Winer ’34 Lei Zhang ’95 Margaret F. Ware ’98 Paul Wing Jr. ’34 Yanping Zhang ’96 Robert A. Ware ’84 Timothy S. Winsky ’80 Hong Zhong ’96 Charles E. Warford ’63 Cheryl J. Winston ’93 Mingjuan Zhu ’99 Robert T. Wargo ’78 Arthur R. Winters ’52 Yizu Zhu ’92 Douglass J. Warner ’59 Charles E. Winters ’39 Zheng J. Zhuang ’97 Huber R. Warner ’58 Richard B. Winters ’76 Allyn J. Ziegenhagen ’59 Donald C. Warren Jr. ’76 William T. Wise ’48 Harry J. Zimmer ’51 Arthur A. Wasserman ’51 Marc B. Wisnudel ’91 Nora A. Zirps ’82 Paul Watkins ’49 Robert H. Wittenauer ’49 Samuel Znaimer ’81 Dawn E. Watkins-Chow ’92 Harvey J. Woehlck ’81 Irwin S. Zonis ’52 Ross O. Watson ’49 Graham A. Woerner ’76 Paul M. Zorn ’50 James B. Weaver ’44 Byron B. Woertz ’39 Eric L. Zweigel ’76 Robert P. Webb ’51 Carl F. Wolf ’53 Melinda L. Zwickert ’77 Alfred E. Wechsler ’55 Clarence W. Wolf Jr. ’62 Andrew L. Zydney ’85 Christopher P. Wedig ’73 Arthur E. Wolters ’50 Norman E. Weeks ’63 Stanley M. Womack ’82 Herbert Wegener Sr. ’61 Kwang J. Won ’79 James C. Wei ’54 Michael S. Wong ’97 Richard J. Weidman ’53 Patrick M. Wong ’78 Ronald J. Weigel ’80 Patrick S. Wong ’62 Robert F. Weimer ’61 Pang T. Woo ’51 Mark Weinberg ’81 Benjamin H. Wood Jr. ’62 Peter C. Weinert ’36 Elwood S. Wood III ’56 Randy D. Weinstein ’98 Frank Wood Jr. ’55 Samantha A. Weinstein ’02 Paul J. Wood ’73 Kenneth A. Weisel ’71 W. K. Woods ’36 Michael H. Weiss ’82 Eugene E. Woodward ’49 Kenneth R. Weisshaar ’72 Mary J. Wornat ’88 Stephen Weisskoff ’57 George R. Worrell ’48 33 Research Highlights

FROM THE DEPARTMENT OF CHEMICAL ENGINEERING •••

Electrospinning of Polymer Fibers Photo:Gregory Rutledge expected for these fibers. Such fibers Professor Gregory C. Rutledge may be used to create composites for lectrostatic fiber spinnning, or ballistic and other impact protection. “electrospinning,” is a technol- Fibers in this size range are also better Eogy that uses electric fields mimics of naturally occurring fibrils applied to charged fluid streams to in the extracellular matrix of tissues produce polymeric fibers that are than are more conventional fibers. The typically hundreds of nanometers feature, combined with other qualities in diameter, two to three orders of electrospun materials such as high of magnitude smaller than fibers porosity and controllable pore size, produced by conventional extrusion offers promise for these materials in methods, and three orders of mag- biomedical applications. The nitude smaller than the typical envisioned textiles also have filtration human hair. Materials manufactured and chemical remediation specifica- from such fibers exhibit potentially tions for chemical and biological unusual fiber morphologies, very warfare protection; for these purposes, high porosity (e.g., >90%) and sur- nanofiber-based nonwoven fabrics are uniquely suited.••• face area (hundreds of square meters A jet of polymer solution per gram), and pore sizes that can generated by electrostatic be varied over a wide range, from 1 spinning--“electrospinning.” Engineering Superior Cells to 1,000 microns. These materials are Professor Gregory Stephanopoulos attracting interest in applications as s lately hardly a day passes diverse as filtration and membranes, without yet another biological In collaboration with Professor Abreakthrough, you may have composites, biomimetic materials for tissue engineering, drug delivery, and Michael Brenner of Harvard asked your microbiologist friend electronics. University, a simple analytical elec- whether she or he knows of a microbe trohydrodynamic model for a slender capable of producing the molecule Professor Rutledge’s group has been charged jet in an electric field has of your choice. In the unlikely event developing the fundamental under- been developed and tested against that one is not readily available, they standing required to operate and carefully designed experiments on may suggest some other microbe that scale up this process for practical model fluids. Using a linear instability makes a similar product that can use. The process itself involves analysis, the origins of several be converted to the desired one, or, charging a polymeric fluid, for varicose and whipping instabilities better yet, your microbiologist friend example by raising it to a voltage of have been identified and quantified. will formulate some screen to select 10-30 kV, in an electric field. The This synergy between theory and microbes and their mutants that can charged fluid ejects a jet that is then experiment has resulted in new produce a whole family of similar accelerated downfield to a collection insight regarding what are the con- products with potentially better prop- device maintained at a lower poten- trolling parameters during electrospin- erties than the one initially sought. tial. En route to the collector, the ning, and has directed development The problem with most such candi- charged fluid stream undergoes one of the technology in new directions. date organisms is that they only make or more fluid instabilities, resulting The theory permits the elaboration of traces of the desired molecule and in a jet that whips around in space, design principles, operating diagrams under conditions that may be difficult thereby rapidly stretching the fluid and scaling relations that help the to implement on an industrial scale. filament to ever smaller diameters. engineer to apply the technology to These microbes must be improved As the filament dries, the solid fibers new materials and obtain new before their potential can be realized. are conveyed to the collector, where products. If you are similarly concerned about a nonwoven material or yarn is a particular disease you may want to obtained. Using high-speed In MIT’s new Institute for Soldier know how a newly discovered gene, photography, the Rutledge group Nanotechnologies (ISN), electrospin- or some other gene(s) buried in the was among the first to identify the ning represents one of the key sequenced genome, can help discover nature of these instabilities and cap- technologies for fabricating inte- a drug for the disease or define a ture them on film. An illuminating grated, multifunctional textiles with strategy for gene therapy. The answer example appeared in Felice Fran- nanoscale structure. By confining to these questions depends critically kel’s book, Envisioning Science: polymer molecules to fibers with The Design and Craft of the Sci- diameters less than 100 nm, new morphologies and properties are ence Image (MIT Press, 2002). RESEARCH see facing page

34 RESEARCH from facing page Presently we are investigating the of diabetes in a particular individual. mechanisms of carbon dioxide Detecting such mechanisms for each on how well we can characterize the fixation by photosynthetic cyanobac- individual would provide the basis for physiological state of cells and tissues teria and its conversion to useful prescribing the right medication and and use this information to prescribe products, such as biopolymers. In par- also developing new drugs with better the necessary genetic changes and/or ticular, we are engineering strains that efficacy and broader applicability in environmental controls to improve have enhanced capability for biopoly- the treatment of this disease. To this such cells. This is also the goal mer production under the hypothesis end, our methods of flux determina- and essence of metabolic engineer- that increased product formation will tion and transcriptional profiling are ing, the area of interest of Professor also lead to increased fixation of CO . deployed along with bioinformatics 2 Gregory Stephanopoulos. These improved cyanobacteria will tools in the study of cell culture thus be able to remove CO from the model systems and in and 2 To achieve the above goal, the flue gases of power plants in shallow animal experiments. Stephanopoulos Laboratory employs ponds and convert this greenhouse state-of-the-art tools such as: DNA effect gas to a useful product that One such study, presently underway in microarrays for transcriptional is also biodegradable. Another system collaboration with scientists from the profiling; stable isotopic tracers, in under investigation is the metabolic Beth Israel Deaconess Medical Center conjunction with software for meta- pathways associated with diabetes and (BIDMC), investigates the transcrip- bolic pathway reconstruction, for the obesity. The novelty of our approach tional profiles, hormonal levels and determination of metabolic fluxes in is that we take an integrated view of diabetic phenotype in diabetic-prone bioreaction networks; and advanced all pathways of relevance to this and normal mice under a variety of bioinformatics methods for data disease inflicting more than 15 million dietary conditions. As the diabetic mining and determination of discrimi- Americans. Specifically, while critical phenotype develops in the course of natory genes and characteristic gene enzymatic reactions and pathways of this experiment, gene activity expression patterns. Besides research importance to diabetes have been profiles are measured by DNA micro- carried out on further developing the adequately described at the biochemi- arrays to determine those genes whose above methods, the latter are also cal and genetic levels, our understand- expression is altered as hyperglycemia profitably deployed for the study and ing of the integrated behavior of these develops. This type of information improvement of various systems of pathways and the factors impacting will provide powerful clues medical and biotechnological interest. flux distribution among such about the molecular mechanisms of Thus, we have investigated amino acid pathways is quite limited. As a result, hyperglycemia and help the discovery production in fermentations of Cory- there are many reasons that can lead of effective drugs for the treatment of nebacterium glutamicum where we to the same diabetic phenotype of diabetes.••• succeeded in increasing the specific hyperglycemia (i.e., elevated blood productivity of lysine sugar concentration) but it is not threefold through the simultaneous possible to identify the specific causes amplification of two important genes. In collaboration with sci-

entists from Merck & Co. Graphic:Gregory Stephanopoulos we increased the yield of a key precursor in the manufacturing of the AIDS drug Crixivan® from 25% to better than 95% through metabolic engineering of the biocon- version pathway of this organism. Our methods allow us now to determine pathway fluxes in vivo at high resolution using advanced gas chromatog- raphy-mass spectrometry (GC-MS) instru- mentation, identify important genes and their characteristic expression pattern associated with highly productive strains or the onset of disease, To increase the low yield of product Y in wild type cells, enzyme E3 is over-expressed. However, due to and deploy these tools for bioreaction network interactions, this genetic change has minimal effect on the rates of product X and the modification of cells Y accumulation. Methods employing isotopic tracers, DNA microarrays, metabolomic and proteomic for industrial and medical measurements and advanced computations are used to elucidate cellular physiology, and guide the applications. next round of genetic changes. Purple circles indicate pool size of metabolites in the network. Arrow thickness depicts relative flux magnitude of the corresponding reactions.

35 GSC-X Activities

BY JASON KRALJ, GSC PRESIDENT

hemical Engineering’s GSC put together some great events for the Photo: Gregory Sands 2001-2002 academic year. We kicked things off during the summer Cwith a joint Materials Science/BEH/Chemical Engineering BBQ catered by campus favorite, Blue Ribbon BBQ, followed soon after by an August clambake to welcome our new students!

During the fall, the TG’s featured both standard menu selections, like pizza and sandwiches, and new items, such as home-brewed beer. At the end of the semester, the GSC coordinated this year’s annual holiday party-probably one of the best ever! From the first-years’ homemade film about a day in the life of a first-year, to the overlapping Nth-years’ and professors’ skit theme of “Cabaret” – the fun was non-stop. Afterwards, everyone enjoyed a catered holiday dinner followed by carol singing.

During IAP, GSC-X helped organize practice oral qualifiers for the first-years, and with the start of the spring semester, we begin our monthly TG’s. As usual, the festivities were dominated by our prospective-student weekends. Each featured lighter fare with the usual assortment of beverages --affording the incoming students an opportunity to mingle with the Nth-years and find out more about the department. Amid mild weather, the final TG of the year was held in the courtyard of Hayden Library, where many students undoubtedly enjoyed deep breaths of spring air, and exhaled sighs of relief knowing that The ChE Holiday Chorale which they had survived another year! included (BOTTOM, L to R) Brian Anderson, Ahmed Ismail With that, the torch was passed on to the next GSC-X committee. We wish them Thomas Gervais and Cyril Delattre all the best and thank everyone who helped us along the way, including Annie (among others) inspired partiers Fowler, Jennifer Shedd, Suzanne Easterly, Arline Benford and everyone in the (TOP) to join the sing-along at Department for helping make this such a successful year! the 2001 ChE Holiday Party!

Chemical Engineering Alumni/ae News, a communications publication for alumni/ae of the Department of Chemical Engineering Gregory Sands, Editor is published annually in Cambridge, MA U.S.A. Department of Chemical Engineering

Massachusetts Institute of Technology NONPROFIT ORG. Department of Chemical Engineering U.S. POSTAGE 77 Massachusetts Avenue, Room 66-350 PAID Cambridge, MA 02139-4307 BOSTON, MA PERMIT NO. 54016 ADDRESS SERVICE REQUESTED

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