DOCSLIB.ORG

Resistance and Response to Selection to Deltamethrin Tn Anopheles S/Nens/S from Zhejiang

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Resistance and Response to Selection to Deltamethrin Tn Anopheles S/Nens/S from Zhejiang Journal of the American Mosquito Control Association, 16(l):9-12,2OOO Copyright O 2OOOby the American Mosquito Control Association, Inc. RESISTANCE AND RESPONSE TO SELECTION TO DELTAMETHRIN TN ANOPHELES S/NENS/S FROM ZHEJIANG. CHINA JINFU WANG College of Life Sciences, Zhejiang University, No. 232, Wen San Road, Hangzhou, Zhejiang 3IOOI2, People's Republic of China ABSTRACT Resistance levels to deltamethrin were measured in 5 natural populations of Anopheles sinensis. The median lethal concentrations (LC.os) of deltamethrin in these populations-were higher than those in suscep- tible strains originating from the same populations, especially in thi Wenzhou population, which had a resistance (RR.o) ratio of 11 relative to its susceptible strain. Resistant strains were ielected with deltamethrin for 12 generations. Resistance levels in resistant strains were 130 to 190-fold higher than in susceptible strains, and l0 to 4o-fold higher than in natural populations. Response of selection (R) i; the resistant strain from the Wenzhou population was less than 0.1, and those in resistant strains from other natural populations were more than 0.1. This suggests that a resistant strain from a natural population with higher resistance has a lower increase in RR than a resistant strain from a natural population with low resistance under identical insecticide selection. These results are discussed in relation to mosquito control strategies. KEY woRDs. Anopheles sinensis, deltamethrin, resistance, response of selection INTRODUCTION plied for oviposition. Larvae from each population were reared in an enamel washbowl containing Anopheles sinensis Wiedemann, an important 2,000 ml of water. Emerging adults were again vector of malaria, is widely distributed in rurai ar- held in the screen cages as described above. eas of Zhejiang, China. Malaria vector control was Larvae and adults were held at 27 -+ l"C with + started using organophosphate insecticides in the 8O lOVo rel- ative humidity, and a photoperiod middle 1960s. The disease has been absent from of 12:12 h (light: dark). When needed, most of areas in Zhejiang since the early 1980s, but females were bloodfed on mice. portion is still present in a few areas, such as in Wenzhou, A of the 4th-stage larvae from each natural population Zhejiang. In 1991, mosquito-curtains soaked with was used for bioassays, with the deltamethrin were used to control An. sinensis in 4th-stage larva of its susceptible strain as the con- the rural area of Wenzhou. This is the lst report of trol. Another portion of the 4th-stage larvae was mosquito conrrol with pyrethroids in Zhejiang, al_ selected with deltamethrin. though pyrethroids have been used in agriculture A resistant strain from each natural population since the early l98os. This work was carried out was selected with deltamethrin for each generation for 2 years and resulted in a sharp decrease of ma- at a dose resulting in 60--70Vo mortality. Each re- laria in this area (Yao 1992). sistant strain was selected for 12 generations and To coordinate research on mosquito-curtain soak- the lethal concentration of the 4th-stage larvae was ing in Wenzhou, we carried out a study of delta- measured in each generation. methrin resistance in mosquitoes. This study was Susceptible strains of An. sinensis with the same undertaken to determine the resistance level in the genetic backgrounds as their respective natural pop- lenzhou population of An. sinensls by comparing ulations were provided by the epidemic prevention the lethal concentration of pyrethroids to its sus- stations in Wenzhou, Jinhua, Ningbo, Hangzhou, ceptible strain. Because pyrethroid resistance is and Jiaxing. These strains had been held under re- now widespread in many crop pest species in Zhe- laxation of insecticide selection for more than l0 jiang, possible resistance of mosquitoes to delta- years (Wang et al. 1996a). methrin in other rural areas of Zhejiang was also Insecticides: Deltamethrin (982o powder) sup- determined. A resistant strain from each natural plied by the Chemical Laboratory, Zhejiang Acad- population was selected with deltamethrin, and the emy of Agricultural Sciences, was diluted to I and increases in their ratios of resistance were analvzed. O.lVo stock solutions with acetone. l,arval bioassay: Resistance of larvae to delta- methdn was measured MATERIALS AND METHODS in a total volume of 2OO ml using the standard World Health Orsanization Mosquitoes: Adult Anopheles sinensis were col- (WHO) rest merhod (WHO 1975, Liu ti85). Sets lected from breeding sites in 5 rural areas (Wen_ of 25 larvae were placed in enamel bowls contain- zhou, Jinhua, Ningbo, Hangzhou, and Jiaxing) dur- ing 20O ml reactive volume. For the range-finding ing the summer of 1995-96. Each adult population test, the concentration gradient points were 2-2.5, collected was held in a screen cage (ZgxZZxZ3 and each regular test contained 6-7 concentrations cm) and fed l5%o glucose solurion. A silk fabric (i.e., the regular test for the Wenzhou natural pop- laid on moistened cotton in a culture plate was sup- ulation contained 7 concentrations from 0.04 to Joumll or rns ArraenrceN Moseuno Con"rnol AssocIATIoN VoL. 16, No. I Table 1. Log-dosage probit mortality data analysis for deltamethrin tested against 5 natural populations (N) and susceptible strains (S)t. Population Strain LCrot LC,, RRro RR,, x2 Wenzhou N 0.3327+ O.O9t2 3.7204 10.91 20.20 16.72*1 S 0.0305 + 0.0012 o.1842 l.Jf Jinhua N 0.1672+ 0.0614 2.9073 6.58 tt.62 13.24* S 0.0254 + 0.0009 o.2501 r.37 Ningbo N 0.1355+ 0.0317 3.0556 4.22 t4.79 10.37* S 0.0321+ 0.0011 o.2066 l.2l Hangzhou N o.to37 + o.o725 2.8254 4.96 12.92 10.04* S 0.0209 + 0.0017 0.2187 2.O9 Jiaxing N o.t44'7 + O.O5'14 2.9526 4.54 14.81 11.73* S 0.0319+ 0.0008 o.1994 1.14 t LC.u, medim lethal concentration; LC,,,,, 99Vo lethal concentration; RR.o, resistance ratio to deltamethrin at LC5o relative to susceptible strains; RRon, resistance ratio to deltamethrin at LC* relative to susccptible strains. 2 12 values lbr the fit-goodness of data to straight lines are given. Includes standtrd enor for the LC.o. 3 * indicates a significant deviation from a linear response. 2.56 ppm with the gradient point : 2) with 3 rep- that the Wenzhou population had the highest resis- licates per concentration. Mortality 20 min after tance level among these natural populations (RR o treatment was recorded. Relative concentrations of : ll, RRs - 20), and other natural populations acetone were used as controls. showed <lO-fold resistance at the LCro (Jinhua: Statistical analysis: Mortality data were ana- 6.58, Ningbo: 4.22, Hangzhort: 4.96, and Jiaxing: Iyzed using the log-probit program of Raymond 4.54) and <I5-fold resistance at the LCee (Jinhua: (1993), based on Finney (1971). This program tests 11.62, Ningbo: 14.79, Hangzhou: 12.92, and Jiax- for the linearity of mortality curves, provides lethal ing: 14.81). The Wenzhou population was signifi- concentrations (LCs), tests whether mortality lines cantly (P < O.O5) more resistant than all other nat- are parallel, and computes resistance ratios (RR). ural populations. Response of selection (R) in each resistant strain was calculated with the equation suggested by Ta- bashnik and McGaughey (1994) as follows: Development of resistance under deltamethrin selection R : log(RR.no,r)/n, Development of resistance to deltamethrin for where RR.oFr2was the resistance ratio at the median each resistant strain under insecticide selection is lethal concentration (LC.o) in the 12th generation shown in Fig. 1. Under selection for 12 generations, of each resistant strain relative to its natural popu- LC.os in resistant strains were more than 4.0 ppm lation, and n was the number of generations under (4.07 ppm for the strain from the Wenzhou popu- insecticide selection. This parameter indicates the lation, 4.34 ppm for the strain from the Jinhua pop- increase in RR in each resistant strain under insec- ulation, 5.01 for the strain from the Ningbo popu- ticide selection, Resistance differences among mos- lation, 4.01 ppm for the strain from the Hangzhou quito populations were analyzed with Student's t- population, and 4.73 ppm for the strain from the test (Hu and Zhang 1985). Jiaxing populations). Compared with the suscepti- ble strain, resistance levels in these resistant strains RESULTS increased approximately 130-, 170-, 150-, 190-, and 150-fold, respectively. These resistant strains did Sensitivity status of 5 natural populations not differ significantly (P > 0.05) in resistance to Thble 1 gives the results of log-dosage probit deltamethrin. mortality analysis of 4th-stage larvae in 5 natural Resistance rations (RR.o) in resistant strains, rel- populations and their susceptible strains. All sus- ative to natural populations, are shown in Table 2. ceptible strains were homogeneous in their re- Under deltamethrin selection for 12 generations at sponse to deltamethrin, with the data points for all 6O-70Vo mortality, resistance levels increased 12- natural populations deviating significantly from a to -4O-fold over natural populations (12.25-told straight line. Parallelism of the mortality lines ob- for the stain from the Wenzhou population, 25.95- tained with 5 susceptible strains was not rejected at fold for the Jinhua population, 36.99-fold for the the 5Vo confidence level; they were not significantly Ningbo population, 38.67-fold for the Hangzhou (P > 0.05) different for susceptibility to deltameth- population, and 32.70-fold for the Jiaxing popula- rin. All natural populations were significantly (P < tion). The RR for the resistant strain from the Wen- 0.05) more resistant than their susceptible strains to zhou population was significantly (P < O.O5) lower deltamethrin.
Load more

Recommended publications
  • Risk Factors for Carbapenem-Resistant Pseudomonas Aeruginosa, Zhejiang Province, China
    Article DOI: https://doi.org/10.3201/eid2510.181699 Risk Factors for Carbapenem-Resistant Pseudomonas aeruginosa, Zhejiang Province, China Appendix Appendix Table. Surveillance for carbapenem-resistant Pseudomonas aeruginosa in hospitals, Zhejiang Province, China, 2015– 2017* Years Hospitals by city Level† Strain identification method‡ excluded§ Hangzhou First 17 People's Liberation Army Hospital 3A VITEK 2 Compact Hangzhou Red Cross Hospital 3A VITEK 2 Compact Hangzhou First People’s Hospital 3A MALDI-TOF MS Hangzhou Children's Hospital 3A VITEK 2 Compact Hangzhou Hospital of Chinese Traditional Hospital 3A Phoenix 100, VITEK 2 Compact Hangzhou Cancer Hospital 3A VITEK 2 Compact Xixi Hospital of Hangzhou 3A VITEK 2 Compact Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University 3A MALDI-TOF MS The Children's Hospital of Zhejiang University School of Medicine 3A MALDI-TOF MS Women's Hospital, School of Medicine, Zhejiang University 3A VITEK 2 Compact The First Affiliated Hospital of Medical School of Zhejiang University 3A MALDI-TOF MS The Second Affiliated Hospital of Zhejiang University School of 3A MALDI-TOF MS Medicine Hangzhou Second People’s Hospital 3A MALDI-TOF MS Zhejiang People's Armed Police Corps Hospital, Hangzhou 3A Phoenix 100 Xinhua Hospital of Zhejiang Province 3A VITEK 2 Compact Zhejiang Provincial People's Hospital 3A MALDI-TOF MS Zhejiang Provincial Hospital of Traditional Chinese Medicine 3A MALDI-TOF MS Tongde Hospital of Zhejiang Province 3A VITEK 2 Compact Zhejiang Hospital 3A MALDI-TOF MS Zhejiang Cancer
    [Show full text]
  • YSA2 Safety Spectacles for Occupational Use
    Jinhua Jinglan Industry & Trade Co.,Ltd. Xiaoshun Town, Jindong District, Jinhua, Zhejiang, China Tel: +86-0579-82955519 Fax: +86-0579-82955517 Email: [email protected] YSA2 Safety Spectacles for Occupational Use Description YSA2 eye-protectors are spectacles for occupational use with polycarbonate lenses and PC frames. Field of Use (Protection capabilities and performance characteristics) This product is intended for protection against low energy impact, as encountered in industry, laboratories, educational establishments, DIY activities, etc. which are likely to damage the eye or impair vision. Service life YSA2 safety spectacles should be replaced after three years in service. Storage and Maintenance Store this product in a soft carry bag or spectacle case when not using it. Cleaning is recommended after each use. The product should be cleaned using a cloth moistened with warm soapy water and dried at room temperature. A suitable clean lens cleaning cloth may also be used. Do not use petrol, chlorinated degreasing fluids, organic solvents or abrasive cleaning agents to clean any part of the equipment. Standards and Approval These safety spectacles are classed as Personal Protective Equipment (PPE) by the European PPE new regulation (EU) 2016/425 and have been shown to comply with this regulation through the Harmonised European Standard NF EN166:2002: SAFETY SPECTACLES. Use Limitation and warning 1. Never modify or alter this product. 2. Do not use this product against hazards other than those specified in this document/product user instructions. 3. Scratched or damaged oculars should be replaced. 4. Materials which may come into contact with the wearer’s skin could cause allergic reactions to susceptible individuals.
    [Show full text]
  • The LEGO Jiaxing Factory the LEGO JIAXING FACTORY the LEGO JIAXING FACTORY Our Innovating Introduction Commitment for Children
    The LEGO Jiaxing Factory THE LEGO JIAXING FACTORY THE LEGO JIAXING FACTORY Our Innovating Introduction commitment for children The LEGO Group is a privately held, family-owned company with headquarters We are committed to emphasising play as a LEGO® play experiences enable learning in Billund (Denmark) and main offices in Enfield (USA), London (UK), Shanghai significant contributor to children’s development. through play by encouraging children to reason (China), and Singapore. Founded in 1932 by Ole Kirk Kristiansen, and based on Play has a profound impact on children’s social, systematically and think creatively. The LEGO the iconic LEGO® brick, it is one of the world’s leading manufacturers of emotional and cognitive skills. This is why all LEGO® System in Play is universally appealing and has creative play materials. play experiences are based on the underlying unlimited possibilities. It encourages children philosophy of learning and development through around the world to engage in fun and creative play play. It is also why we remain focused on providing and allows them to build anything they can imagine. fun and engaging play materials of the highest quality and safety to children. All LEGO products are developed in Denmark by more than 250 designers that represent 35 different Children’s best interests and well-being have always nationalities. While our designers have solid insight been at the very core of our values: Imagination into children’s play patterns and interests, our most – Creativity – Fun – Learning – Caring – Quality. valuable insight comes from children themselves. Our core values are important to us not only We include children in concept and product testing because they define who we are as a company and phases as an integrated part of our product what we stand for, but also because they guide us innovation cycle.
    [Show full text]
  • Factory Address Country
    Factory Address Country Durable Plastic Ltd. Mulgaon, Kaligonj, Gazipur, Dhaka Bangladesh Lhotse (BD) Ltd. Plot No. 60&61, Sector -3, Karnaphuli Export Processing Zone, North Potenga, Chittagong Bangladesh Bengal Plastics Ltd. Yearpur, Zirabo Bazar, Savar, Dhaka Bangladesh ASF Sporting Goods Co., Ltd. Km 38.5, National Road No. 3, Thlork Village, Chonrok Commune, Korng Pisey District, Konrrg Pisey, Kampong Speu Cambodia Ningbo Zhongyuan Alljoy Fishing Tackle Co., Ltd. No. 416 Binhai Road, Hangzhou Bay New Zone, Ningbo, Zhejiang China Ningbo Energy Power Tools Co., Ltd. No. 50 Dongbei Road, Dongqiao Industrial Zone, Haishu District, Ningbo, Zhejiang China Junhe Pumps Holding Co., Ltd. Wanzhong Villiage, Jishigang Town, Haishu District, Ningbo, Zhejiang China Skybest Electric Appliance (Suzhou) Co., Ltd. No. 18 Hua Hong Street, Suzhou Industrial Park, Suzhou, Jiangsu China Zhejiang Safun Industrial Co., Ltd. No. 7 Mingyuannan Road, Economic Development Zone, Yongkang, Zhejiang China Zhejiang Dingxin Arts&Crafts Co., Ltd. No. 21 Linxian Road, Baishuiyang Town, Linhai, Zhejiang China Zhejiang Natural Outdoor Goods Inc. Xiacao Village, Pingqiao Town, Tiantai County, Taizhou, Zhejiang China Guangdong Xinbao Electrical Appliances Holdings Co., Ltd. South Zhenghe Road, Leliu Town, Shunde District, Foshan, Guangdong China Yangzhou Juli Sports Articles Co., Ltd. Fudong Village, Xiaoji Town, Jiangdu District, Yangzhou, Jiangsu China Eyarn Lighting Ltd. Yaying Gang, Shixi Village, Shishan Town, Nanhai District, Foshan, Guangdong China Lipan Gift & Lighting Co., Ltd. No. 2 Guliao Road 3, Science Industrial Zone, Tangxia Town, Dongguan, Guangdong China Zhan Jiang Kang Nian Rubber Product Co., Ltd. No. 85 Middle Shen Chuan Road, Zhanjiang, Guangdong China Ansen Electronics Co. Ning Tau Administrative District, Qiao Tau Zhen, Dongguan, Guangdong China Changshu Tongrun Auto Accessory Co., Ltd.
    [Show full text]
  • Certain Vacuum Insulated Flasks and Components Thereof by Reason of Infringement Of: (1) the Sole Claim of U.S
    UNITED STATES INTERNATIONAL TRADE COMMISSION Washington, D.C. In the Matter of Investigation No. 337-TA-1216 CERTAIN VACUUM INSULATED FLASKS AND COMPONENTS THEREOF NOTICE OF A COMMISSION DETERMINATION NOT TO REVIEW AN INITIAL DETERMINATION GRANTING A JOINT MOTION TO TERMINATE THE INVESTIGATION AS TO RESPONDENT DUNHUANG GROUP A/K/A DHGATE BASED ON A SETTLEMENT AGREEMENT AGENCY: U.S. International Trade Commission. ACTION: Notice. SUMMARY: Notice is hereby given that the U.S. International Trade Commission has determined not to review an initial determination (“ID”) (Order No. 17) of the presiding chief administrative law judge (“CALJ”) granting a joint motion to terminate the investigation as to respondent Dunhuang Group a/k/a DHgate (“DHgate”) based on a settlement agreement. FOR FURTHER INFORMATION CONTACT: Michael Liberman, Esq., Office of the General Counsel, U.S. International Trade Commission, 500 E Street, SW, Washington, D.C. 20436, telephone (202) 205-2392. Copies of non-confidential documents filed in connection with this investigation may be viewed on the Commission’s electronic docket (EDIS) at https://edis.usitc.gov. For help accessing EDIS, please email [email protected]. General information concerning the Commission may also be obtained by accessing its Internet server at https://www.usitc.gov. Hearing-impaired persons are advised that information on this matter can be obtained by contacting the Commission’s TDD terminal on (202) 205-1810. SUPPLEMENTARY INFORMATION: On September 3, 2020, the Commission instituted this investigation under section 337 of the Tariff Act of 1930, as amended, 19 U.S.C. 1337 (“section 337”), based on a complaint filed by Steel Technology LLC d/b/a Hydro Flask and Helen of Troy Limited (collectively, “Complainants,” or “Hydro Flask”).
    [Show full text]
  • A Case Study in Central Zhejiang Provinc
    Proceedings of the Fábos Conference on Landscape and Greenway Planning Volume 6 Adapting to Expanding and Contracting Article 60 Cities 2019 Understanding Governance Structures in Shaping Greenway Implementation in City-Regions: A Case Study in Central Zhejiang Province, China Jun Xian Chen Faculty of Architecture, Building and Planning, The University of Melbourne, [email protected] Sun Sheng Han Faculty of Architecture, Building and Planning, The University of Melbourne, [email protected] Si Qing Chen Faculty of Architecture, Building and Planning, The University of Melbourne, [email protected] Follow this and additional works at: https://scholarworks.umass.edu/fabos Part of the Environmental Design Commons, Geographic Information Sciences Commons, Historic Preservation and Conservation Commons, Landscape Architecture Commons, Nature and Society Relations Commons, Remote Sensing Commons, Urban, Community and Regional Planning Commons, and the Urban Studies and Planning Commons Recommended Citation Chen, Jun Xian; Han, Sun Sheng; and Chen, Si Qing (2019) "Understanding Governance Structures in Shaping Greenway Implementation in City-Regions: A Case Study in Central Zhejiang Province, China," Proceedings of the Fábos Conference on Landscape and Greenway Planning: Vol. 6 , Article 60. DOI: https://doi.org/10.7275/6bde-3604 Available at: https://scholarworks.umass.edu/fabos/vol6/iss1/60 This Article is brought to you for free and open access by ScholarWorks@UMass Amherst. It has been accepted for inclusion in Proceedings of the Fábos Conference on Landscape and Greenway Planning by an authorized editor of ScholarWorks@UMass Amherst. For more information, please contact [email protected]. Understanding Governance Structures in Shaping Greenway Implementation in City-Regions: A Case Study in Central Zhejiang Province, China Cover Page Footnote The uthora s are grateful to all the government officials involved in the interviews.
    [Show full text]
  • Sustainable Development of New Urbanization from the Perspective of Coordination: a New Complex System of Urbanization-Technology Innovation and the Atmospheric Environment
    atmosphere Article Sustainable Development of New Urbanization from the Perspective of Coordination: A New Complex System of Urbanization-Technology Innovation and the Atmospheric Environment Bin Jiang 1, Lei Ding 1,2,* and Xuejuan Fang 3 1 School of International Business & Languages, Ningbo Polytechnic, Ningbo 315800, Zhejiang, China; [email protected] 2 Institute of Environmental Economics Research, Ningbo Polytechnic, Ningbo 315800, Zhejiang, China 3 Ningbo Institute of Oceanography, Ningbo 315832, Zhejiang, China; [email protected] * Correspondence: [email protected] Received: 26 September 2019; Accepted: 25 October 2019; Published: 28 October 2019 Abstract: Exploring the coordinated development of urbanization (U), technology innovation (T), and the atmospheric environment (A) is an important way to realize the sustainable development of new-type urbanization in China. Compared with existing research, we developed an integrated index system that accurately represents the overall effect of the three subsystems of UTA, and a new weight determination method, the structure entropy weight (SEW), was introduced. Then, we constructed a coordinated development index (CDI) of UTA to measure the level of sustainability of new-type urbanization. This study also analyzed trends observed in UTA for 11 cities in Zhejiang Province of China, using statistical panel data collected from 2006 to 2017. The results showed that: (1) urbanization efficiency, the benefits of technological innovation, and air quality weigh the most in the indicator systems, which indicates that they are key factors in the behavior of UTA. The subsystem scores of the 11 cities show regional differences to some extent. (2) Comparing the coordination level of UTA subsystems, we found that the order is: coordination degree of UT > coordination degree of UA > coordination degree of TA.
    [Show full text]
  • Attachment I
    Foreign Producers of Steel Threaded Rod: The People's Republic of China Barcode:3795402-02 A-570-104 INV - Investigation - Shipper Shipper Full Address Shipper Email Shipper Phone Number Shippper Fax Number Shipper Website Aaa Line International Room 502-A01 East Area Bldg., 129 Jiatai Road, Shanghai, Shanghai, China 200000 Not Available +86 21 5054 1289 Not Available Not Available Ace Fastech Co., Ltd. No. 583-28, Chang'An North Road, Wuyan Town, Haiyan, Zhejiang, China, 314300 Not Available Not Available Not Available Not Available Aerospace Precision Corp. (Shanghai) Room 3E, 1903 Pudong Ave., Pudong, Shanghai, China 200120 Not Available +86 187 2262 6510 +86 187 5823 7600 Not Available Aihua Holding Group Co., Ltd. 12F, New Taizhou Building, Jiaojiang, Zhejiang, China, 318000 Not Available +86 576 8868 5829 +86 576 8868 5815 Not Available All Tech Hardware Ltd. Suite 2406, Dragon Pearl Complex, No. 2123 Pudong Ave. Shanghai, China 200135 Not Available Not Available Not Available Not Available All World Shipping Corp. Room 503, Building B, Guangpi Cultural Plaza, No. 2899A Xietu Road, Shanghai, China 20030 [email protected] +86 21 6487 9050 +86 21 6487 9071 allworldshipping.com Alloy Steel Products Inc. No. 188 Siping Road No.89, Hongkou, Shanghai, China 200086 Not Available +86 21 6409 2892 Not Available Not Available America And Asia Products Inc. Rm. 508, No. 188 Siping Road, Hongkou, Shanghai, China 200086 Not Available +86 21 6142 8806 Not Available Not Available Ams No Chinfast Co., Ltd. 68 Qin Shan Road, Haiyan, Jiaxing, Zhejiang, China 314000 Not Available +86 573 8211 9789 Not Available Not Available Ams No Jiaxing Xinyue Standard Parts Co., Ltd.
    [Show full text]
  • Jinhua Qinggan Granule, a Chinese Herbal Medicine Against COVID-19, Induces Rapid Changes in the Plasma Levels of IL-6 and IFN-Γ
    medRxiv preprint doi: https://doi.org/10.1101/2020.06.08.20124453; this version posted June 12, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission. Jinhua Qinggan granule, a Chinese herbal medicine against COVID-19, induces rapid changes in the plasma levels of IL-6 and IFN-γ Yasunari Kageyama1,2, Koichi Aida1, Kimihiko Kawauchi1, Masafumi Morimoto1, Tomoka Ebisui1, Tetsu Akiyama3, Tsutomu Nakamura1,3,* 1Takanawa Clinic, Minato-ku, Tokyo, Japan 2Tokai University Hospital, Isehara-shi, Kanagawa, Japan 3Laboratory of Molecular and Genetic Information, Institute for Quantitative Biosciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan *Corresponding Author Tsutomu Nakamura (E-mail: [email protected]) Abstract Background: Currently, effective vaccines or specific therapeutic agents against COVID-19 are not available. However, in China, traditional Chinese herbal medicines have provided therapeutic benefit to patients with COVID-19. Jinhua Qinggan granule (JHQGG) is a Chinese multi-herbal formula previously developed for the treatment of H1N1 influenza and has been encouraged for patients clinically suspected of COVID-19 during medical observation. However, the immunological mechanism for the efficacy of JHQGG has not been confirmed. Objectives: We thus examined whether the administration of JHQGG affects hematological and immunological measures in healthy individuals. Method: We enrolled 18 healthy volunteers, all of whom tested negative for antibodies to SARS-CoV-2. Peripheral blood samples were collected 1 h after oral administration of JHQGG and subjected to hematological, biochemical, and cytokine tests.
    [Show full text]
  • SUPPLIER LIST AUGUST 2019 Cotton on Group - Supplier List 2
    SUPPLIER LIST AUGUST 2019 Cotton On Group - Supplier List _2 COUNTRY FACTORY NAME SUPPLIER ADDRESS STAGE TOTAL % OF % OF % OF TEMP WORKERS FEMALE MIGRANT WORKER WORKERS WORKER CHINA NINGBO FORTUNE INTERNATIONAL TRADE CO LTD RM 805-8078 728 LANE SONGJIANG EAST ROAD SUP YINZHOU NINGBO, ZHEJIANG CHINA NINGBO QIANZHEN CLOTHES CO LTD OUCHI VILLAGE CMT 104 64% 75% 6% GULIN TOWN, HAISHU DISTRICT NINGBO, ZHEJIANG CHINA XIANGSHAN YUFA KNITTING LTD NO.35 ZHENYIN RD, JUEXI STREET CMT 57 60% 88% 12% XIANGSHAN COUNTY NINGBO CITY, ZHEJIANG CHINA SUNROSE INTERNATIONAL CO LTD ROOM 22/2 227 JINMEI BUILDING NO 58 LANE 136 SUP SHUNDE ROAD, HAISHU DISTRICT NINGBO, ZHEJIANG CHINA NINGBO HAISHU WANQIANYAO TEXTILE CO LTD NO 197 SAN SAN ROAD CMT 26 62% 85% 0% WANGCHAN INDUSTRIAL ZONE NINGBO, ZHEJIANG CHINA ZHUJI JUNHANG SOCKS FACTORY DAMO VILLAGE LUXI NEW VILLAGE CMT 73 38% 66% 0% ZHUJI CITY ZHEJIANG CHINA SKYLEAD INDUSTRY CO LIMITED LAIMEI INDUSTRIAL PARK SUP CHENGHAI DISTRICT, SHANTOU CITY GUANGDONG CHINA CHUANGXIANG TOYS LIMITED LAIMEI INDUSTRIAL PARK CMT 49 33% 90% 0% CHENGHAI DISTRICT SHANTOU, GUANGDONG CHINA NINGBO ODESUN STATIONERY & GIFT CO LTD TONGJIA VILLAGE, PANHUO INDUSTRIAL ZONE SUP YINZHOU DISTRICT NINGBO CITY, ZHEJIANG CHINA NINGBO ODESUN STATIONERY & GIFT CO LTD TONGJIA VILLAGE, PANHUO INDUSTRIAL ZONE CMT YINZHOU DISTRICT NINGBO CITY, ZHEJIANG CHINA NINGBO WORTH INTERNATIONAL TRADE CO LTD RM. 1902 BUILDING B, CROWN WORLD TRADE PLAZA SUP NO. 1 LANE 28 BAIZHANG EAST ROAD NINGBO ZHEJIANG CHINA NINGHAI YUEMING METAL PRODUCT CO LTD NO. 5 HONGTA ROAD
    [Show full text]
  • China's May FDI Rises 13.4%
    Economy & Policy | Market & Trade | Infrastructure & Development | Shipping | Logistics & Transportation WEEKLY NEWSLETTER Week 24/25 June 9-22th, 2013 www.amassfreight.com Economy China’s 2013 GDP Growth Forecast at 8.1 Percent general PPI of May, according to the NBS. CSFJN | 19-June-2013 & More >> Policy Experts attending the China Macro-economic Forum on June 15 believed expedited reforms are key to break out of the current trap. They appealed for more decisive U.S. consumer prices up 0.1% in May actions in reforms related to urbanization, finance, and Xinhua | 19-June-2013 fiscal and tax system. U.S. Consumer Price Index (CPI) rose 0.1 percent in May According to the report published on the same day, the on seasonally adjusted basis, indicating the inflation GDP growth in 2013 is expected to reach 8.1 percent; remained subdued, the Labor Department said on Market & Trade CPI may grow by 2.9 percent, and PPI recovery can be Tuesday. Infrastructure & Development seen in the end of this year; M1 and M2 growth are predicted to be 13.6 percent and 15.5 percent. The report said the energy prices rose 0.4 percent last Shipping month, with gasoline prices flat but increases in the Logistics & Transportation More >> electricity and natural gas prices accounting for the rise. Meanwhile, the food costs turned down by 0.1 percent in May. China's May PPI down 2.9 percent Xinhua | 9-June-2013 Excluding the volatile food and energy categories, the so-called "core" inflation index rose 0.2 percent in May.
    [Show full text]
  • Factory Name
    Factory Name Factory Address BANGLADESH Company Name Address AKH ECO APPARELS LTD 495, BALITHA, SHAH BELISHWER, DHAMRAI, DHAKA-1800 AMAN GRAPHICS & DESIGNS LTD NAZIMNAGAR HEMAYETPUR,SAVAR,DHAKA,1340 AMAN KNITTINGS LTD KULASHUR, HEMAYETPUR,SAVAR,DHAKA,BANGLADESH ARRIVAL FASHION LTD BUILDING 1, KOLOMESSOR, BOARD BAZAR,GAZIPUR,DHAKA,1704 BHIS APPARELS LTD 671, DATTA PARA, HOSSAIN MARKET,TONGI,GAZIPUR,1712 BONIAN KNIT FASHION LTD LATIFPUR, SHREEPUR, SARDAGONI,KASHIMPUR,GAZIPUR,1346 BOVS APPARELS LTD BORKAN,1, JAMUR MONIPURMUCHIPARA,DHAKA,1340 HOTAPARA, MIRZAPUR UNION, PS : CASSIOPEA FASHION LTD JOYDEVPUR,MIRZAPUR,GAZIPUR,BANGLADESH CHITTAGONG FASHION SPECIALISED TEXTILES LTD NO 26, ROAD # 04, CHITTAGONG EXPORT PROCESSING ZONE,CHITTAGONG,4223 CORTZ APPARELS LTD (1) - NAWJOR NAWJOR, KADDA BAZAR,GAZIPUR,BANGLADESH ETTADE JEANS LTD A-127-131,135-138,142-145,B-501-503,1670/2091, BUILDING NUMBER 3, WEST BSCIC SHOLASHAHAR, HOSIERY IND. ATURAR ESTATE, DEPOT,CHITTAGONG,4211 SHASAN,FATULLAH, FAKIR APPARELS LTD NARAYANGANJ,DHAKA,1400 HAESONG CORPORATION LTD. UNIT-2 NO, NO HIZAL HATI, BAROI PARA, KALIAKOIR,GAZIPUR,1705 HELA CLOTHING BANGLADESH SECTOR:1, PLOT: 53,54,66,67,CHITTAGONG,BANGLADESH KDS FASHION LTD 253 / 254, NASIRABAD I/A, AMIN JUTE MILLS, BAYEZID, CHITTAGONG,4211 MAJUMDER GARMENTS LTD. 113/1, MUDAFA PASCHIM PARA,TONGI,GAZIPUR,1711 MILLENNIUM TEXTILES (SOUTHERN) LTD PLOTBARA #RANGAMATIA, 29-32, SECTOR ZIRABO, # 3, EXPORT ASHULIA,SAVAR,DHAKA,1341 PROCESSING ZONE, CHITTAGONG- MULTI SHAF LIMITED 4223,CHITTAGONG,BANGLADESH NAFA APPARELS LTD HIJOLHATI,
    [Show full text]