NFYC, Nuclear Y gamma polyclonal antibody

uclear transcription factor Y gamma (NFYC) is one sub- or Research Use Only. Not for Nunit of a trimeric complex, forming a highly conserved FDiagnostic or Therapeutic Use. transcription factor that binds with high specificity to CCAAT Purchase does not include or carry motifs in the regions in a variety of . NFYC any right to resell or transfer this (C subunit) forms a tight dimer with the B subunit, a prereq- product either as a stand-alone product or as a component of another uisite for subunit A association. The resulting trimer binds to product. Any use of this product other DNA with high specificity and affinity. Subunits B and C each than the permitted use without the contain a -like motif. Observation of the histone na- express written authorization of Allele ture of these subunits is supported by two types of evidence: Biotech is strictly prohibited sequence alignments and experiments with mutants.

Website: www.allelebiotech.com Call: 1-800-991-RNAi/858-587-6645 Buffers (Pacific Time: 9:00AM~5:00PM) Purified chicken polyclonal antibody supplied in PBS with Email: [email protected] 0.09% (W/V) sodium azide. This antibody is purified through a protein G column and eluted out with both high and low pH buffers and neutralized immediately after elution then fol- lowed by dialysis against PBS. Box 1 | Basic Info

Cat. No. ABP-PAB-01079 Animal ID RC40104 Immunogen Host Chicken Partial protein comprised of amino acids 72 - 186 of the hu- Reactivity Human man nuclear transcription factor Y gamma (NFYC) protein. Format Purified Accession number NM_014223 Amount 100 µg Application Alternative Name(s): Tested by peptide-specific ELISA (1:1,000). HSM, CBFC, HAP5, CBF-C, NF-YC, H1TF2A, transactivator HSM-1, C subunit of CCAAT-binding factor, C subunit of transcription factor NF-Y, histone H1 tran- scription factor large subunit 2A Storage Maintain refrigerated at 2-8ºC for up to 6 months. For long term storage store at -20ºC. Avoid repeated freeze-thaw cycles. References:

1. Taira T, Sawai M, Ikeda M, Tamai K, Iguchi- Ariga SM, Ariga H: Cell cycle-dependent switch of up-and down-regulation of human hsp70 expression by interaction between c- and CBF/NF-Y. J. Biol. Chem. 274(34): 24270-24279 (1999). 2. Dmitrenko V, Garifulin O, Kavsan V: Isolation and sequence analysis of the cDNA encoding subunit C of human CCAAT-binding transcription factor. Gene 197(1-2): 161-163 (1997). 3. Bellorini M, Zemzoumi K, Farina A, Berthelsen J, Piaggio G, Mantovani R: Cloning and expres- sion of human NF-YC. Gene 193(1): 119-125 (1997).

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