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Understanding Cancer Immunotherapy PATIENT RESOURCE one FREE take Fifth Edition UNDERSTANDING CANCER IMMUNOTHERAPY CONTENT REVIEWED BY A DISTINGUISHED MEDICAL ADVISORY BOARD PRP PATIENT RESOURCE PUBLISHING® Published in partnership with UNDERSTANDING CANCER IMMUNOTHERAPYFifth Edition IN THIS GUIDE 1 Explaining the Immune System 3 Renal Cell Carcinoma Survivor: Peggy Zuckerman 4 Exploring Immunotherapy 7 Development Milestones 8 Realizing Immunotherapy’s Potential 9 Bladder Cancer Survivor: Fred Almeida Chief Executive Officer Mark A. Uhlig 14 Understanding Clinical Trials Co-Editor-in-Chief Charles M. Balch, MD, FACS 15 Side Effects Co-Editor-in-Chief Howard L. Kaufman, MD, FACS 16 Glossary Co-Editor-in-Chief Sandip P. Patel, MD 17 Cancer Immunotherapy Clinical Trials by Disease Senior Vice President Debby Easum Vice President, Operations Leann Sandifar 37 Assistance & Support Resources Vice President, Publications Dana Campbell CO-EDITORS-IN-CHIEF Managing Editor Colleen Scherer Charles M. Balch, MD, FACS Staff Writer Marli Murphy Professor of Surgery, The University of Texas Graphic Designer Michael St. George MD Anderson Cancer Center Editor-in-Chief, Patient Resource LLC Medical Illustrator Todd Smith Past President, Society of Surgical Oncology Production Manager Elaina Smith Circulation Manager Sonia Wilson Howard L. Kaufman, MD, FACS Vice Presidents, Amy Galey Division of Surgical Oncology, Massachusetts Business Development Kathy Hungerford General Hospital Stephanie Myers Kenney Chief Medical Officer, Replimune, Inc. Past President, Society for Immunotherapy of Cancer Office Address 8455 Lenexa Drive Overland Park, KS 66214 Sandip P. Patel, MD For Additional Information [email protected] Associate Professor, UC San Diego Advisory Board Visit our website at Co-Leader, Experimental Therapeutics PatientResource.com to read bios of Deputy Director, San Diego Center for Precision our Medical and Patient Advisory Board. Immunotherapy Assistant Director, Clinical Trials Office Tara Withington, CAE – Executive Director, SITC For Additional Copies: To order additional copies of Patient Resource SPECIAL Mary Dean, JD, CAE – Associate Executive Director, SITC Cancer Guide: Understanding Cancer Immunotherapy, Alicia Schuessler, CAE – Director of Education, SITC visit PatientResource.com, call 913-725-1600, THANKS or email [email protected]. Jody Felski – Senior Development Manager, SITC TO Claire Leischer, MS – Senior Manager of Online Education, SITC Editorial Submissions: Editorial submissions should be sent to Erin PachecoSITC – Program Cancer Manager, SITC [email protected]. The Society forconnectED Immunotherapy of Cancer (SITC) is Disclaimer: Information presented in Patient Resource Cancer Guide: the world’s leading member-driven organization specifically dedicated to improving Understanding Cancer Immunotherapy is not intended as a substitute for Yourcancer freepatient resource outcomes for by cancer advancing immunotherapy the science and patientapplication educationof cancer from the advice given by your health care provider. The opinions expressed in immunotherapy. Established in 1984, SITC, a 501(c)(3) not-for-profit organization, Patient Resource Cancer Guide: Understanding Cancer Immunotherapy Societyserves scientists, for Immunotherapy clinicians, academicians, of Cancer patients, (SITC) patient advocates, government are those of the authors and do not necessarily reflect the views of the publisher. Although Patient Resource Cancer Guide: Understanding Can- representatives and industry leaders from Featuring more than SITC70 educational Cancer Immunotherapy classes and activities cer Immunotherapy strives to present only accurate information, readers connectEDaround the world. Through educational should not consider it as professional advice, which can only be given Access the following free online activitiesprograms to learn that about foster cancer scientific immunotherapy: exchange by a health care provider. Patient Resource, its authors, and its agents Your free resource for cancer immunotherapy patient education from the • Download the Understanding andCancer collaboration, Immunotherapy SITC aims4th Edition to one Patient day shall not be responsible or in any way liable for the continued currency Society for Immunotherapy of Cancer (SITC)make the word “cure” a reality for cancer of the information or for any errors, omissions or inaccuracies in this pub- Resource Guide (available in English and Spanish) Featuring more than 70 educational classespatients and activitieseverywhere. lication, whether arising from negligence or otherwise or for any conse- • AccessHear the from following a freecancer online survivoractivities to andlearn anabout expert cancer immunotherapy: in the field how the immune quences arising therefrom. Patient Resource, its authors, and its agents system• Download can thebe Understanding harnessed Cancer to fight Immunotherapy cancer 4th inEdition The Patient Global Promise of make no representations or warranties, whether express or implied, as Resource Guide (available in English and Spanish) Immunotherapy webinar to the accuracy, completeness or timeliness of the information contained • Hear from a cancer survivor and an expert in the field how the immune herein or the results to be obtained from using the information. The • Learnsystem about can be immunotherapy harnessed to fight cancer clinical in The Global trials Promise in the of IntroductionFOR MORE to Cancer Immunotherapy ImmunotherapySITC webinar Cancer Immunotherapy publisher is not engaged in rendering medical or other professional services. SITC andCancer• theLearn Immune about immunotherapy Immunotherapy System clinical online trials activity in the Introduction to connectEDCancer Immunotherapy The publication of advertisements, whether paid or not, and survivor stories and the ImmuneconnectED System online activity INFORMATION SITC Cancer Immunotherapy connectED• Engage with the Understanding Cancer Immunotherapy online activity to learn aboutis not thean endorsement. If medical or other expert assistance is required, the Your free• resourceEngage with for cancerthe Understanding immunotherapy Cancer patient Immunotherapy education online from activity the to learn about the services of a competent professional person should be sought. Finding OnlineSociety cancerpotential forpotential Immunotherapy immunotherapy side side effectseffects of Cancer of cancer (SITC)of cancerimmunotherapypatient immunotherapy education has neverSEE PAGE 16 Sign up for a free SITC connectED account at sitcancer.org/patient © 2018 Patient Resource LLC. All rights reserved. Featuring more than 70 educational classes and activities been easier.Sign upSITC for Cancer a free SITC Immunotherapy connectED account connectED at sitcancer.org/patient provides ® Access the following free online activities to learn about cancer immunotherapy: PRP PATIENT RESOURCE PUBLISHING Your free resourceresources for cancer from SITCimmunotherapy• Download experts the Understanding and Cancer partnering Immunotherapypatient 4organizationsth Editioneducation Patient from the Resource Guide (available in English and Spanish) SITC-0618-423 For reprint information, email [email protected]. Your free resource for cancer immunotherapySociety patient for Immunotherapy educationin one convenient from of• CancerHear theplace. from a cancer (SITC) survivor and an expert in the field how the immune system can be harnessed to fight cancer in The Global Promise of Immunotherapy webinar Society for Immunotherapy of Cancer (SITC) SITC-0618-423 With your FREE SITC• Learn connectED about immunotherapy account, clinical trials in theyou Introduction have to accessCancer Immunotherapy to: Featuring more than 70 educationaland the Immune classes System online activityand activities • an adaptive and• Engagepersonalized with the Understanding learning Cancer Immunotherapy platform online activity to learn about the Featuring more than 70 educational classesAccess and the activities following free online activitiespotential sideto effectslearn of cancerabout immunotherapy cancer immunotherapy: • interactive educationalSign up for a free SITC connectED activities account at sitcancer.org/patientin a variety of learning Access the following free online activities to learn about• cancer Download immunotherapy: the Understanding Cancer Immunotherapy 4th Edition Patient formats Resourceth Guide (available in English and Spanish) Understanding Cancer Immunotherapy 4 Edition SITC-0618-423 • Download the • up-to-date Patient cancer immunotherapy resources Resource Guide (available in English and Spanish)• Hear from a cancer survivor and an expert in the field how the immune • multiple CME-/CE-certified courses • Hear from a cancer survivor and an expert in the fieldsystem how can the be immune harnessed to fight cancer in The Global Promise of system can be harnessed to fight cancer in The GlobalImmunotherapy Promise of webinar Immunotherapy webinar • Learn about immunotherapy clinical trials in the Introduction to Cancer Immunotherapy Start exploring classes and resources at • Learn about immunotherapy clinical trials in the Introductionand the Immune to Cancer System Immunotherapy online activity and the Immune System online activity • Engage with the Understanding Cancer Immunotherapy online activity to learn sitcancer.org/connectabout the ED • Engage with the Understanding Cancer Immunotherapypotential online side activity effects to oflearn cancer about immunotherapy the SITC-1017-404
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