Anti-KLK15 Antibody (ARG65597)

Product datasheet [email protected]

ARG65597 Package: 100 μl anti-KLK15 antibody Store at: -20°C

Summary

Product Description Rabbit Polyclonal antibody recognizes KLK15

Tested Reactivity Hu

Tested Application IHC-P, WB

Host Rabbit

Clonality Polyclonal

Isotype IgG

Target Name KLK15

Antigen Species Human

Immunogen Fusion protein of human KLK15

Conjugation Un-conjugated

Alternate Names ACO protease; Kallikrein-15; ACO; EC 3.4.21.-; HSRNASPH

Application Instructions

Application table Application Dilution

IHC-P 25-100

WB 200-1000

Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Calculated Mw 28 kDa

Properties

Form Liquid

Purification Purified by antigen-affinity chromatography.

Buffer PBS (pH 7.4), 0.05% Sodium azide and 40% Glycerol

Preservative 0.05% Sodium azide

Stabilizer 40% Glycerol

Concentration 0.5 mg/ml

Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.

Note For laboratory research only, not for drug, diagnostic or other use.

www.arigobio.com 1/3 Bioinformation

Database links GeneID: 55554 Human

Swiss-port # Q9H2R5 Human

Gene Symbol KLK15

Gene Full Name kallikrein-related peptidase 15

Background Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In prostate cancer, this gene has increased expression, which indicates its possible use as a diagnostic or prognostic marker for prostate cancer. The gene contains multiple polyadenylation sites and alternative splicing results in multiple transcript variants encoding distinct isoforms.

Function Protease whose physiological substrate is not yet known. [UniProt]

Research Area Cancer antibody; Cell Biology and Cellular Response antibody; Signaling Transduction antibody

Images

ARG65597 anti-KLK15 antibody IHC-P image

Immunohistochemistry: Paraffin-embedded Human gastric cancer tissue stained with ARG65597 anti-KLK15 antibody (left) at 1:15 dilution, or the same antibody preincubated with fusion protein (right). (Original magnification: ×200).

ARG65597 anti-KLK15 antibody WB image

Western blot: 40 μg of 231 and HT29 cell lysates (left to right) stained with ARG65597 anti-KLK15 antibody at 1:200 dilution. Exposure time: 1 minute.

www.arigobio.com 2/3 ARG65597 anti-KLK15 antibody IHC-P image

Immunohistochemistry: Paraffin-embedded Human breast cancer tissue stained with ARG65597 anti-KLK15 antibody (left) at 1:15 dilution, or the same antibody preincubated with fusion protein (right). (Original magnification: ×200).