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Safety Data Sheet SAFETY DATA SHEET Creation Date 07-Oct-2003 Revision Date 21-Dec-2020 Revision Number 6 SECTION 1: IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING 1.1. Product identifier Product Description: Diphenylphosphoryl azide Cat No. : 409040000; 409040050; 409040250; 409041000; 409045000 Synonyms DPPA CAS-No 26386-88-9 EC-No. 247-644-0 Molecular Formula C12 H10 N3 O3 P 1.2. Relevant identified uses of the substance or mixture and uses advised against Recommended Use Laboratory chemicals. Uses advised against No Information available 1.3. Details of the supplier of the safety data sheet Company UK entity/business name Fisher Scientific UK Bishop Meadow Road, Loughborough, Leicestershire LE11 5RG, United Kingdom EU entity/business name Acros Organics BVBA Janssen Pharmaceuticalaan 3a 2440 Geel, Belgium E-mail address [email protected] 1.4. Emergency telephone number For information US call: 001-800-ACROS-01 / Europe call: +32 14 57 52 11 Emergency Number US:001-201-796-7100 / Europe: +32 14 57 52 99 CHEMTREC Tel. No.US:001-800-424-9300 / Europe:001-703-527-3887 SECTION 2: HAZARDS IDENTIFICATION 2.1. Classification of the substance or mixture CLP Classification - Regulation (EC) No 1272/2008 Physical hazards Based on available data, the classification criteria are not met Health hazards ______________________________________________________________________________________________ ACR40904 Page 1 / 10 SAFETY DATA SHEET Diphenylphosphoryl azide Revision Date 21-Dec-2020 ______________________________________________________________________________________________ Acute oral toxicity Category 3 (H301) Acute dermal toxicity Category 2 (H310) Acute Inhalation Toxicity - Vapors Category 2 (H330) Skin Corrosion/Irritation Category 2 (H315) Serious Eye Damage/Eye Irritation Category 2 (H319) Specific target organ toxicity - (single exposure) Category 3 (H335) Environmental hazards Based on available data, the classification criteria are not met Full text of Hazard Statements: see section 16 2.2. Label elements Signal Word Danger Hazard Statements H301 - Toxic if swallowed H315 - Causes skin irritation H319 - Causes serious eye irritation H335 - May cause respiratory irritation H310 + H330 - Fatal in contact with skin or if inhaled Precautionary Statements P310 - Immediately call a POISON CENTER or doctor/physician P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing P302 + P352 - IF ON SKIN: Wash with plenty of soap and water P332 + P313 - If skin irritation occurs: Get medical advice/attention P280 - Wear protective gloves/protective clothing/eye protection/face protection P337 + P313 - If eye irritation persists: Get medical advice/attention 2.3. Other hazards No information available SECTION 3: COMPOSITION/INFORMATION ON INGREDIENTS 3.1. Substances Component CAS-No EC-No. Weight % CLP Classification - Regulation (EC) No 1272/2008 Phosphorazidic acid, diphenyl ester 26386-88-9 EEC No. 247-644-0 > 95 Acute tox. 3 (H301) Acute Tox. 2 (H310) Acute Tox.2 (H330) Skin Irrit. 2 (H315) Eye Irrit. 2 (H319) STOT SE 3 (H335) ______________________________________________________________________________________________ ACR40904 Page 2 / 10 SAFETY DATA SHEET Diphenylphosphoryl azide Revision Date 21-Dec-2020 ______________________________________________________________________________________________ Full text of Hazard Statements: see section 16 SECTION 4: FIRST AID MEASURES 4.1. Description of first aid measures General Advice Show this safety data sheet to the doctor in attendance. Immediate medical attention is required. Eye Contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. In the case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Skin Contact Wash off immediately with plenty of water for at least 15 minutes. Immediate medical attention is required. Ingestion Do NOT induce vomiting. Call a physician or poison control center immediately. Inhalation Remove to fresh air. If not breathing, give artificial respiration. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Immediate medical attention is required. Self-Protection of the First Aider Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and prevent spread of contamination. 4.2. Most important symptoms and effects, both acute and delayed . Symptoms of overexposure may be headache, dizziness, tiredness, nausea and vomiting 4.3. Indication of any immediate medical attention and special treatment needed Notes to Physician Treat symptomatically. Symptoms may be delayed. SECTION 5: FIREFIGHTING MEASURES 5.1. Extinguishing media Suitable Extinguishing Media Water spray, carbon dioxide (CO2), dry chemical, alcohol-resistant foam. Extinguishing media which must not be used for safety reasons No information available. 5.2. Special hazards arising from the substance or mixture Thermal decomposition can lead to release of irritating gases and vapors. Keep product and empty container away from heat and sources of ignition. Hazardous Combustion Products Nitrogen oxides (NOx), Carbon monoxide (CO), Carbon dioxide (CO2), Oxides of phosphorus. 5.3. Advice for firefighters As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full ______________________________________________________________________________________________ ACR40904 Page 3 / 10 SAFETY DATA SHEET Diphenylphosphoryl azide Revision Date 21-Dec-2020 ______________________________________________________________________________________________ protective gear. Thermal decomposition can lead to release of irritating gases and vapors. SECTION 6: ACCIDENTAL RELEASE MEASURES 6.1. Personal precautions, protective equipment and emergency procedures Ensure adequate ventilation. Use personal protective equipment as required. Keep people away from and upwind of spill/leak. Evacuate personnel to safe areas. 6.2. Environmental precautions Should not be released into the environment. 6.3. Methods and material for containment and cleaning up Soak up with inert absorbent material. Keep in suitable, closed containers for disposal. 6.4. Reference to other sections Refer to protective measures listed in Sections 8 and 13. SECTION 7: HANDLING AND STORAGE 7.1. Precautions for safe handling Wear personal protective equipment/face protection. Do not get in eyes, on skin, or on clothing. Use only under a chemical fume hood. Do not breathe mist/vapors/spray. Do not ingest. If swallowed then seek immediate medical assistance. Hygiene Measures Handle in accordance with good industrial hygiene and safety practice. Keep away from food, drink and animal feeding stuffs. Do not eat, drink or smoke when using this product. Remove and wash contaminated clothing and gloves, including the inside, before re-use. Wash hands before breaks and after work. 7.2. Conditions for safe storage, including any incompatibilities Keep container tightly closed in a dry and well-ventilated place. Keep under nitrogen. To maintain product quality: Keep refrigerated. Technical Rules for Hazardous Substances (TRGS) 510 Storage Class (LGK) Class 6.1A (Germany) 7.3. Specific end use(s) Use in laboratories SECTION 8: EXPOSURE CONTROLS/PERSONAL PROTECTION 8.1. Control parameters Exposure limits This product, as supplied, does not contain any hazardous materials with occupational exposure limits established by the region specific regulatory bodies Biological limit values This product, as supplied, does not contain any hazardous materials with biological limits established by the region specific regulatory bodies ______________________________________________________________________________________________ ACR40904 Page 4 / 10 SAFETY DATA SHEET Diphenylphosphoryl azide Revision Date 21-Dec-2020 ______________________________________________________________________________________________ Monitoring methods BS EN 14042:2003 Title Identifier: Workplace atmospheres. Guide for the application and use of procedures for the assessment of exposure to chemical and biological agents. MDHS70 General methods for sampling airborne gases and vapours Derived No Effect Level (DNEL) No information available Route of exposure Acute effects (local) Acute effects Chronic effects Chronic effects (systemic) (local) (systemic) Oral Dermal Inhalation Predicted No Effect Concentration No information available. (PNEC) 8.2. Exposure controls Engineering Measures Use only under a chemical fume hood. Ensure that eyewash stations and safety showers are close to the workstation location. Wherever possible, engineering control measures such as the isolation or enclosure of the process, the introduction of process or equipment changes to minimise release or contact, and the use of properly designed ventilation systems, should be adopted to control hazardous materials at source Personal protective equipment Eye Protection Goggles (European standard - EN 166) Hand Protection Protective gloves Glove material Breakthrough time Glove thickness EU standard Glove comments Nitrile rubber See manufacturers - EN 374 (minimum requirement) Viton (R) recommendations Skin and body protection Long sleeved clothing Inspect gloves before use. Please observe the instructions regarding permeability and breakthrough
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