BZP (Benzylpiperazine)

Total Page:16

File Type:pdf, Size:1020Kb

BZP (Benzylpiperazine) A Guide To Substance Misuse For Medical Professionals Drug Category BZP (Benzylpiperazine) 8IBUJTJULOPXOBT 1BSUZ1JMMT 5IF4VCTUBODF #;1 1JQFSB[JOF " % % % 8IBUJTJU #;1JTBTUJNVMBOUXIJDIHBJOFEQPQVMBSJUZBTBMFHBM BMUFSOBUJWFUPESVHTTVDIBT4QFFEBOE95$ 8IFSFEPFTJUDPNFGSPN /FX;FBMBOE*UJTDPNNPOMZGPVOEJOA)FBE4IPQT BOEBU(JHTBOE'FTUJWBMTFUD Positive Neutral Negative 3BQJENPPEFMFWBUJPO $IBOHFTJOCPEZUFNQFSBUVSF 3FEVDFETFYVBMTFOTBUJPO 4LJOUJOHMJOH 'MVTIJOH .JMEIFBEBDIF 'FFMJOHTPGFVQIPSJB XPOEFS %JMBUJPOPGQVQJMT )BOHPWFSMJLFTZNQUPNT BNB[FNFOU FMBUJPO *ODSFBTFEEFTJSFUPNPWF %FDSFBTFEBQQFUJUF 'BUJHVF $MPTFEFZFIBMMVDJOBUJPOTXJUI *OTPNOJB NVTJD 5JNF%ZTNPSQIJB *ODSFBTFEIFBSUSBUF $POGVTJPO .JMENFNPSZMPTT Nausea 44 Section 1 Miscellaneous Substances Gammahydroxybutyrate (GHB) Drug Category 4USFFUOBNF ()# (#) MJRVJE&DTUBTZ %SVHFòFDU &VQIPSJDTFEBUJWFFòFDU&ò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òFDUTPGMPOHUFSNVTF UIFSFGPSFUIFDPOTFRVFODFT PGTVDIVTFBSFVOLOPXO 0WFSEPTF3JTL 4JNJMBSUPCBSCJUVSBUFT UIFSFJTBöOFMJOFCFUXFFOUIFBNPVOUUIBUJTSFRVJSFEUPBDIJFWFUIF EFTJSFEFòFDUBOEUIBUXIJDIXJMMMFBEUPDPNB5IFSFJTBMTPIJHISJTLPGPWFSEPTFTIPVME()# CFNJYFEXJUITJNJMBSTVCTUBODFTTVDIBTBMDPIPMPSPUIFSDFOUSBMOFSWPVTTZTUFNEFQSFTTBOUT 45 A Guide To Substance Misuse For Medical Professionals Drug Category Miscellaneous Substances Kratom (Mitragyna speciosa) 8IBUJTJULOPXOBT ,SBUPN,FUVN,BLVBN*UIBOH5IPN 8IBUJTJU ,SBUPN .JUSBHZOB4QFDJPTB JTBMFBGZUSFFUIBU HSPXTGSPNNFUFSTUBMM*UTMFBWFTBSFDIFXFEBT BOPQJBUFTVCTUJUVUFBOETUJNVMBOUJO5IBJMBOEBOE 4PVUI&BTU"TJB QSJNBSJMZBNPOHUIFXPSLJOHDMBTT *UIBTBSFMBUJWFMZMPOHIJTUPSZPGIVNBOVTF 8IFSFEPFTJUDPNFGSPN 5IBJMBOEBOE4&"TJB What are the eff ects? Positive Neutral Negative 4JNVMUBOFPVTTUJNVMBUJPO 3FMBUJWFMZTIPSUEVSBUJPO 7FSZCJUUFSUBTUF sedation %J[[JOFTT OBVTFBBOEPS 'FFMJOHTPGFNQBUIZ $IBOHFJOBCJMJUZUPGPDVTFZFT WPNJUJOHBUIJHIFSEPTFT 'FFMJOHTPGFVQIPSJB .JMEEFQSFTTJPO 7JWJEXBLJOHESFBNT 'FFMJOHIPUBOETXFBUZ 6TFGVMXJUIQIZTJDBMMBCPS )BOHPWFSTJNJMBSUPBMDPIPM 46 Section 1 Miscellaneous Substances Over-the counter (OTC) medicines Drug Category %FTDSJQUJPO 5IFSFBSFNBOZNFEJDJOFTUIBUDBOCFCPVHIU XJUIPVUQSFTDSJQUJPO 05$ BOEIBWFQPUFOUJBMGPS BCVTF5IFTFNPPEBMUFSJOHQSFQBSBUJPOTGBMMJOUP UISFFDBUFHPSJFTDPSSFTQPOEJOHUPUIFJSTJNJMBSJUZ UPPQJBUFT TUJNVMBOUTPSTFEBUJWFT0OMZUIFNPTU DPNNPOMZVTFEBSFNFOUJPOFEIFSF 0QJBUFUZQF 5IFTF05$NFEJDJOFTDPOUBJOPQJBUFMJLFTVCTUBODFT 5IFZBSFEFTJHOFEUPTVQQSFTTUIFDPVHIJOHSFøFY4PNFESVHVTFSTXJMMCVZUIFTFESVHTUP IFMQXJUIXJUIESBXBM XIJMFPUIFSTXJMMVTFUIFNUPTVQQMFNFOUUIFFòFDUTPGJMMJDJUESVHT 5IFTFQSFQBSBUJPOTBSFNBEFGSPNBTZSVQZCBTF TPJOKFDUJPOJTVOMJLFMZ"EBOHFSUIBUSFNBJOT JTUIFJOKFDUJPOPGQPXEFSPSUBCMFUGPSNVMBUJPOT6TVBMMZUIFTFBSFBDPNCJOBUJPOPGDPEFJOF BOEBTQJSJO XIJDIDBOSFTVMUJOBTQJSJOQPJTPOJOH"OPUIFSEBOHFSJTQBSBDFUBNPMQPJTPOJOH BOE$PEJOFEFQFOEFODZNBZBMTPPDDVS 4UJNVMBOUUZQF 5IFTF05$NFEJDJOFTDPOUBJOFJUIFSDBòFJOFPSFQIFESJOFBOEBDUJOBTJNJMBSXBZUP BNQIFUBNJOF5IFZBSFGPVOEJOOBTBMEFDPOHFTUBOUT DPVHITZSVQTBOEDPMESFNFEJFT5IFZ IBWFMPOHCFFONJTVTFECZESJWFSTUPLFFQUIFNBXBLFXIFOUSBWFMMJOHMPOHEJTUBODFT 4FEBUJWFUZQF .BOZ05$DPVHIBOEDPMESFNFEJFTDPOUBJOBOUJIJTUBNJOFT XIJDIDBOIBWFBOPUJDFBCMF TFEBUJWFFòFDU UIFEBOHFSPGXIJDINBZCFJODSFBTFECZJUTDPNCJOFEVTFXJUIBMDPIPM $ZDMJ[JOFJTQSPCBCMZUIFNPTUNJTVTFEBOUJIJTUBNJOF BOENPSFPGUFOUIBOOPUJTJOKFDUFEJO MBSHFRVBOUJUJFTXJUIPQJBUFTJOBOBUUFNQUUPSFQSPEVDFUIFFòFDUTPGEJDPOBM BOPQJBUFXIJDI DPOUBJOTDZDMJ[JOF 47 A Guide To Substance Misuse For Medical Professionals Drug Category Miscellaneous Substances Sally D (Salvia Divinorum) 8IBUJTJULOPXOBT 1BTUPSB 4IFQIFSEFTTT)FSC .BSJB1BTUPSB ZFSCBEF .BSJB 4BMMZ% 8IBUJTJU 4BMWJBEJWJOPSVNJTBTPGUMFBWFEHSFFOQMBOU.PEFSO VTFJODMVEFTCPUITNPLJOHBOEDIFXJOHUIFMFBWFT 8IFOUIFMFBWFTBSFDIFXFE UIFRVJEBOECJUUFSKVJDF BSFIFMEJOUIFNPVUIUPJODSFBTFBCTPSQUJPO 8IFSFEPFTJUDPNFGSPN 4JFSSB.B[BUFDSFHJPOPG.FYJDP What are the eff ects? Positive Neutral Negative QPXFSGVMPQFOBOEDMPTFEFZF TIPSUEVSBUJPO XIFOTNPLFE PWFSMZJOUFOTFFYQFSJFODFT WJTVBMT HFOFSBMDIBOHFJO GFFMJOHPGAQSFTFODFPSFOUJUZ SBEJDBMQFSTQFDUJWFTIJGUJOH consciousness contact increase in sensual and BMUFSFEQFSDFQUJPOT GFBS UFSSPSBOEQBOJD BFTUIFUJDBQQSFDJBUJPO DSFBUJWFESFBNMJLFFYQFSJFODF øVTIJOH JODSFBTFEQFSTQJSBUJPO TFOTBUJPOPGQIZTJDBMQVTI QPTTJCMFEJóDVMUZJOUFHSBUJOH JOTJHIUJOUPQFSTPOBMJTTVFT QSFTTVSF PSXJOE FYQFSJFODFT TFOTBUJPOPGBMUFSOBUFSFBMJUJFT 48 Section 1 Miscellaneous Substances Various Other Drugs Drug Category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òFDUTBOEJTVTFEJOUIFUSFBUNFOUPGTDIJ[PQISFOJBBOEPUIFSQTZDIPTJT*UJT QSFTDSJCFEVOEFSUIFCSBOEOBNF.FMMFSJM 4BOEP[ BTBXIJUFUBCMFU TZSVQPSTVTQFOTJPO*O TNBMMEPTFT JUJTVTFEGPSUIFUSFBUNFOUPGSFTUMFTTOFTTBOEBHJUBUJPOJOUIFFMEFSMZ 49 A Guide To Substance Misuse For Medical Professionals Drug Category Barbiturates (FOFSBMJOGPSNBUJPOPO#BSCJUVSBUFT #BSCJUVSBUFTBSFQSFTDSJCFEGPSTFWFSFTMFFQQSPCMFNT BOEUPDPOUSPMFQJMFQTZ5IFJSVTFGPSJOTPNOJBIBT CFFOMBSHFMZSFQMBDFECZUIFCFO[PEJB[FQJOFT NJOPS USBORVJMMJTFST BMUIPVHIBGFXFMEFSMZQFPQMFBSFTUJMM QSFTDSJCFECBSCJUVSBUFT Drugs include: COMMON STREET THERAPEUTIC DOSE DRUG NAME BRAND NAME NAME RANGE Amytal and Amytal Amylobarbitone 60-200mg Sodium Butobarbitone Soneryl 100-200mg Methyl Prominal 100-600mg phenobarbitone Pentobarbitone Nembutal Nembies 100-200mg Phenobarbitone Luminal 60-180mg Quinalbarbitone Seconal Sodium Seggies 50-100mg Quinalbarbitone and Tuinal Chewies 100-200mg Amylobarbitone 50 Section 1 Barbiturates 4USFFU6TF #BSCJUVSBUFTDBOCFTXBMMPXFECVUNPSFPGUFOBNPOHIFBWZVTFSTUIFZBSFEJTTPMWFEJOXBUFS Drug Category and injected. %SVH&òFDU #BSCJUVSBUFTBSFEFQSFTTBOUTPSEPXOFST5IFZXPSLPOUIFXIPMFOFSWPVTTZTUFNQSPEVDJOHB HFOFSBMJTFETFEBUJPO3FTQJSBUJPOBOEIFBSUSBUFBSFSFEVDFEBOEUIFSFJTBHFOFSBMMPXFSJOHPG BOYJFUZMFWFMT5IFSFJTBMTPTPNFEJTSVQUJPOPGUIPVHIUQSPDFTTFTBOENFNPSZ)JHIFSEPTFT MFBEUPMPTTPGQIZTJDBMDPPSEJOBUJPOBOEUIFSFJTiESVOLFOw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öDBUJPOPWFSFJHIUEBZTJTDPNNPO Amytal Sodium Capsules 51 A Guide To Substance Misuse For Medical Professionals Drug Category Benzodiazepine (FOFSBMJOGPSNBUJPOPO#FO[PEJB[FQJOFT 5IFSFBSFUXPHSPVQTPGCFO[PEJB[FQJOFTUIF iBOYJPMZUJDTwXIJDIBSFQSFTDSJCFEGPSBOYJFUZBOENJME EFQSFTTJPO BOEUIFiIZQOPUJDTwXIJDIBSFQSFTDSJCFE GPSJOTPNOJB TFWFSFTMFFQQSPCMFNT Drugs include: THERAPEUTIC DOSE DRUG NAME STREET NAME MAIN USE RANGE Diazepam Vallies Anxiety 5-20mg Lorazepam Anxiety 1-4mg Flurazepam Insomnia 15-30mg Nitrazepam Moggies Insomnia 5-10mg Temazepam Rugby Balls Insomnia 10-20mg Flunitrazepam Roofi es Insomnia 0.5-1mg Valium Tablets 52 Section 1 Benzodiazepine 4USFFU6TF #FO[PEJB[FQJOFTBSFTXBMMPXFEJOMBSHFOVNCFSTPSDBOCFJOKFDUFECZDSVTIJOHUBCMFUT Drug Category PSJOKFDUJOHKFMMZGSPNDBQTVMFT%PTFMFWFMTWBSZCVUEBJMZEPTFTPGUJNFTUIFOPSNBM UIFSBQFVUJDSBOHFIBWFCFFOSFQPSUFE#FO[PEJB[FQJOFTBSFPGUFONJYFEXJUIPUIFSESVHT*O 4DPUMBOE GPSFYBNQMF BSFDFOUUSFOEIBTCFFOUIFVTFPGUFNHFTJD BOPQJBUF BOEUFNB[FQBN BCFO[PEJB[FQJOF JODPNCJOBUJPO %SVH&òFDU #FO[PEJB[FQJOFTBSFEFQSFTTBOUTPSiEPXOFSTw5IFZBDUPOUIFQBSUPGUIFCSBJOBTTPDJBUFEXJUI BOYJFUZ SFEVDFUFOTJPOBOEJOEVDFTMFFQ&WFOBUMPXEPTFT CFO[PEJB[FQJOFTDBOBòFDUNFOUBM BOEQIZTJDBMGVODUJPOJOH CVUMFTTTPUIBOBMDPIPM"UIJHIFSEPTFT UIFZQSPEVDFiESVOLFOwBOE TPNFUJNFTBHHSFTTJWFCFIBWJPVS4VSQSJTJOHMZ NJYJOHCFO[PEJB[FQJOFTXJUIPUIFSiEPXOFSTw TVDIBTCBSCJUVSBUFT BMDPIPMPSPQJBUFTQSPEVDFTBTUJNVMBOUFòFDUXIJDIJODSFBTFTBMFSUOFTT BOEDPOöEFODF %FQFOEFODF "UMPXEPTFTXJUIJOUIFUIFSBQFVUJDSBOHF UPMFSBODFEPFTOPUEFWFMPQUPBOZHSFBUFYUFOUBOE
Recommended publications
  • Palliative Care Case of the Month
    PALLIATIVE CARE CASE OF THE MONTH “Treating Non-Infectious Diarrhea” by Robert Arnold, MD Volume 19, No. 98 August, 2019 Case 1: Mr. Jones is a 58-year-old man with short gut Three drugs are used because of their ability to slow down the syndrome. Palliative Care was consulted for goals of care, gut, allowing for more time for absorption of intestinal fluids a however quickly it became clear uncontrolled diarrhea was a decrease of diarrhea. The most well-know is loperamide, a larger priority. He said having to change the bag every few hours synthetic opiate which has minimal absorption. The dosing is 4 completely interfered with his living a normal life. He said, “I’d mg after one’s first bowel movement and then 2 mg after every rather die than have all of this diarrhea.” unformed stool, up to 16 mg (in palliative care patients there is some data for use up to 54 mg).9, 10 Loperamide should be Case 2: A 62-year-old woman with non-small cell lung cancer continued for 12 hours after diarrhea is stopped. Adverse effects is receiving immunotherapy. She has done quite well but is include mostly constipation, abdominal cramps, nausea and distressed by her diarrhea. She tried Lomotil and Imodium but rarely CNS effects like fatigue or dizziness. Cases of torsades de neither worked. When seeing her palliative care doctor, she said, pointes and death have been reported with higher than “It isn’t worth treating my cancer if I can’t live a normal life.” 9 recommended doses.
    [Show full text]
  • Analysis of Benzylpiperazine-Like Compounds Hiroyuki Inoue 1
    鑑識科学,9(2),165―184(2004) 165 ―Technical Note― Analysis of Benzylpiperazine-like Compounds Hiroyuki Inoue1,YukoT.Iwata1, Tatsuyuki Kanamori1, Hajime Miyaguchi1, Kenji Tsujikawa1, Kenji Kuwayama1, Hiroe Tsutsumi2, Munehiro Katagi2, Hitoshi Tsuchihashi2 and Tohru Kishi1 National Research Institute of Police Science 631, Kashiwanoha, Kashiwa, Chiba 2770882, Japan1 Forensic Science Laboratory, Osaka Prefectural Police H. Q. 1318, Hommachi, Chuo-ku, Osaka, Osaka 5410053, Japan2 (Received 6 January 2004; accepted 6 March 2004) 1-Benzylpiperazine (BZP) and 1-(3-tri‰uoromethylphenyl)piperazine, newly controlled as narcotics in Japan on 2003, and their analogues were analyzed. The analytical data with color test, thin layer chromatography (TLC), infrared spectroscopy (IR), gas chromatography/mass spectrometry (GC/MS) and liquid chromatography/mass spectrometry (LC/MS) are presented. The BZP-like compounds were less sensitive to Simon's reagent than amphetamine type stimulants on spot plates. Using on-site screening kit based on Simon's test (X-Checker), BZP indicated almost the same result as methamphetamine. For TLC, the solvent system, methanol -25 aqueous ammonia (100 : 1.5), was the best among the systems examined. Iodoplatinate reagent was the most sensitive one to detect BZP. The IR spectra showed su‹cient diŠerences to make identiˆcation. Trimethylsilylation was the most appropriate choice for the GC/MS analysis of BZP-like compounds in terms of the peak shapes, separation and stability (using a J&W DB-5MS column). In LC/MS analysis, the gradient elution (10 mM formic acid and acetonitrile) using a Waters Symmetry Shield C18 column achieved discrimination of isomers except for 1-(2-‰uorophenyl) piperazine and 1-(4-‰uorophenyl)piperazine.
    [Show full text]
  • Anti-Diarrheal Activity and Brine Shrimp Lethality Bioassay of Methanolic Extract of Cordyline Fruticosa (L.) A
    Naher et al. Clinical Phytoscience (2019) 5:15 https://doi.org/10.1186/s40816-019-0109-z ORIGINAL CONTRIBUTION Open Access Anti-diarrheal activity and brine shrimp lethality bioassay of methanolic extract of Cordyline fruticosa (L.) A. Chev. leaves Sharmin Naher1*, Md. Abdullah Aziz1, Mst. Irin Akter2, S. M. Mushiur Rahman1, Sadiur Rahman Sajon1 and Kishor Mazumder1,3 Abstract Background: Cordyline fruticosa (L.) A. Chev. (Asparagaceae) is a plant which is traditionally used for the treatment of cough, bloody cough, diarrhea, dysentery, high fever, difficulties in urine, bloody urine, small pox, madness, skin eruptions, joint pains, rheumatic bone pains, sore throat, neck pain, bleeding hemorrhoids and inflammation in the digestive tract. Therefore, the present work aims to investigate the antidiarrheal and cytotoxic activities of methanolic extract of Cordyline fruticosa leaves in mice and brine shrimp, respectively. Methods: The effects of the methanol extract of Cordyline fruticosa leaves (MCFL) on castor oil-induced diarrhea, magnesium sulphate induced diarrhea and charcoal meal test in mice were investigated. In addition, brine shrimp lethality bioassay method was used to evaluate cytotoxic activity of MCFL. Results: In castor oil induced diarrheal test, MCFL at the dose of 200, 400 and 800 mg/kg body weight significantly (∗P< 0.05, versus control) and dose-dependently reduced the frequency of diarrhea. The frequency of magnesium sulphate-induced diarrhea was significantly reduced by MCFL at the dose of with 800 mg/kg. In the charcoal meal test, the extract at the dose of 400 and 800 mg/kg body weight significantly (∗P< 0.05) reduced the distance travelled by charcoal along the intestinal tract when compare with control.
    [Show full text]
  • Quest Diagnostics Prescription Drug Monitoring Reference Guide
    Clinical Drug Monitoring Reference Guide Clinical Drug Monitoring Test List with Test Codes Drug Class P P,D,M P,D D,M D Drug Class P P,D,M P,D D,M D Drug Class P P,D,M P,D D,M D Alcohol Metabolites 90079 16910 92142 16217 Cocaine Metabolite 92225 70248 16888 90082 16916 Naltrexone 93753 Amphetamines 92222 70245 16885 70209 16913 Eszopiclone 91251 Opiates 92230 18991 16891 70237* 16298* Amphetamines Fentanyl 36278 36279 36280 18996 16900 Oxycodone 92231 18992 16892 70238 16920 91590 91589 92484 92483 with Reflex d/l Isomers Gabapentin 70205 16904 Phencyclidine 92232 18993 16893 90083 16921 Antidepressants (urine) 94032 Heroin Metabolite 92226 90081 16911 90333 90329 Pregabalin 70208 16908 Antidepressants (serum) 94031 Marijuana Metabolite 92227 18989 16889 70233 16917 Propoxyphene 92233 18995 16894 70239 16922 Antipsychotics (urine) 94528 MDMA/MDA 92228 90078 16909 90334 90331 Synthetic Cannabinoids 93027 Antipsychotics (serum) 94529 Meperidine 70206 16905 Synthetic Stimulants 90322 Barbiturates 92223 70246 16886 70230 16912 Methadone Metabolite 92229 18990 16890 70234 16918 Tapentadol 90244 90243 Benzodiazepines 92224 70247 16887 70231 16914 Methamphetamine Tramadol 70207 16906 90319 Buprenorphine 16207 70249 16901 18998 16213 d/l Isomers Tricyclic Antidepressants 70204 16903 Buprenorphine 93093 93094 Methylphenidate 90247 90246 with Naloxone Zolpidem 91258 Mitragynine 39241 39240 Carisoprodol 18999 16902 *Includes oxycodone drug class Test Profiles Profile Name Base Profile Profile 1 Profile 2 Profile 3 Profile 4 Profile 5 Profile 6
    [Show full text]
  • Federal Register/Vol. 85, No. 178/Monday, September 14, 2020
    Federal Register / Vol. 85, No. 178 / Monday, September 14, 2020 / Notices 56631 agreements. All non-confidential DEPARTMENT OF JUSTICE ADDRESSES: Written comments should written submissions will be available for be sent to: Drug Enforcement public inspection at the Office of the Drug Enforcement Administration Administration, Attention: DEA Federal Secretary and on EDIS. [Docket No. DEA–713] Register Representative/DPW, 8701 The Commission vote for these Morrissette Drive, Springfield, Virginia 22152. All requests for a hearing must determinations took place on September Importer of Controlled Substances Application: Cerilliant Corporation be sent to: Drug Enforcement 8, 2020. Administration, Attn: Administrator, The authority for the Commission’s AGENCY: Drug Enforcement 8701 Morrissette Drive, Springfield, determination is contained in section Administration, Justice. Virginia 22152. All request for a hearing 337 of the Tariff Act of 1930, as ACTION: Notice of application. should also be sent to: (1) Drug amended (19 U.S.C. 1337), and in Part SUMMARY: Cerilliant Corporation has Enforcement Administration, Attn: 210 of the Commission’s Rules of applied to be registered as an importer Hearing Clerk/OALJ, 8701 Morrissette Practice and Procedure (19 CFR part of basic class(es) of controlled Drive, Springfield, Virginia 22152; and 210). substance(s). Refer to Supplemental (2) Drug Enforcement Administration, Attn: DEA Federal Register By order of the Commission. Information listed below for further Representative/DPW, 8701 Morrissette Issued: September 8, 2020. drug information. DATES: Drive, Springfield, Virginia 22152. Lisa Barton, Registered bulk manufacturers of the affected basic class(es), and SUPPLEMENTARY INFORMATION: In Secretary to the Commission. applicants therefore, may file written accordance with 21 CFR 1301.34(a), this [FR Doc.
    [Show full text]
  • Pharmacy and Poisons (Third and Fourth Schedule Amendment) Order 2017
    Q UO N T FA R U T A F E BERMUDA PHARMACY AND POISONS (THIRD AND FOURTH SCHEDULE AMENDMENT) ORDER 2017 BR 111 / 2017 The Minister responsible for health, in exercise of the power conferred by section 48A(1) of the Pharmacy and Poisons Act 1979, makes the following Order: Citation 1 This Order may be cited as the Pharmacy and Poisons (Third and Fourth Schedule Amendment) Order 2017. Repeals and replaces the Third and Fourth Schedule of the Pharmacy and Poisons Act 1979 2 The Third and Fourth Schedules to the Pharmacy and Poisons Act 1979 are repealed and replaced with— “THIRD SCHEDULE (Sections 25(6); 27(1))) DRUGS OBTAINABLE ONLY ON PRESCRIPTION EXCEPT WHERE SPECIFIED IN THE FOURTH SCHEDULE (PART I AND PART II) Note: The following annotations used in this Schedule have the following meanings: md (maximum dose) i.e. the maximum quantity of the substance contained in the amount of a medicinal product which is recommended to be taken or administered at any one time. 1 PHARMACY AND POISONS (THIRD AND FOURTH SCHEDULE AMENDMENT) ORDER 2017 mdd (maximum daily dose) i.e. the maximum quantity of the substance that is contained in the amount of a medicinal product which is recommended to be taken or administered in any period of 24 hours. mg milligram ms (maximum strength) i.e. either or, if so specified, both of the following: (a) the maximum quantity of the substance by weight or volume that is contained in the dosage unit of a medicinal product; or (b) the maximum percentage of the substance contained in a medicinal product calculated in terms of w/w, w/v, v/w, or v/v, as appropriate.
    [Show full text]
  • Highlights of This Issue
    THURSDAY, OCTOBER 4, 1973 WASHINGTON, D.C. HIGHLIGHTS OF THIS ISSUE This listing does not affect the legal status of any document published in this issue. Detailed table of contents appears inside. ECONOMIC STABILIZATION— CLC Phase IV pay and price regulations for certain reg­ istered, practical, and trained nurses (2 documents); effective 10—1—73....................... ........................ 27528, 27529 CLC allows Phase IV price increases for rubber tire and tube products; effective 10—8—73............................. ....... 27528 October 4, 1973— -Pages 27501-27574 METHAQUALONE— Justice Department classifies as Schedule II controlled substance; effective 10—4—73 27516 ARTISTS' PAINTS AND SUPPLIES— Consumer Product Safety Commission exempts from lead content restric­ tions; effective 12—3—73...-......... ........................................ 27514 DEFENSE CONTRACTS— Cost Amounting Standards Board extends disclosure statement filing requirements; effective 4— 1—74............................. ....................................... 27507 PUBLIC ASSISTANCE— HEW proposal on determin­ ing paternity of children receiving aid; comments by 1 1 -5 -7 3 ............................................ -. ............ : ........ 27530 SUGAR— USDA declares and reprorates 1973 quota deficits for Hawaii and Peru................... .................... ........................ 27509 USDA requires no proportionate shares for 1974 sugarbeet crop..--....................... ..............."...................... — 27510 PEANUTS— USDA proposes 1974
    [Show full text]
  • Western Judicial Circuit Felony Drug Court
    Western Judicial Circuit Felony Drug Court (Athens-Clarke and Oconee Counties) PARTICIPANT HANDBOOK This handbook belongs to: 325 E. Washington Street, Suite 210 Athens, Georgia 30601 (706) 208-7078 (706) 613-3179 (fax) Table of Contents Welcome 3 Overview 4-5 Confidentiality 5 Treatment 5 Program Phases 6-10 Commencement 11 Program Rules 12-14 Program Fees 15 The Drug Court Team 15 Staffings 15 Court Appearances 16 Incentives 17 Sanctions and Treatment Responses 17 Termination 18 Drug/Chemical Testing 19 Prohibited Drugs/Permitted Medications 20-27 Travel/Leave Requests 27 Compliance & Home Visits/Job Checks, Searches 28 Search Requirements 28 Commencement Ceremony 29 Conclusion 29 Important Phone Numbers 30 Community Resources 31 Attachment I: Random Drug Screen Policy Attachment II: Urine Abstinence Testing/Incidental Alcohol Exposure Contract (original signed copy on file with Felony Drug Court) Attachment III: Emergency On-call Telephone Policy Attachment IV: Felony Drug Court Contract 2 Welcome to the Western Judicial Circuit Felony Drug Court! This Handbook was designed to answer your questions and provide specific information about what you must do in order to successfully complete the requirements of the Western Judicial Circuit Felony Drug Court Program. As a participant, you are expected to follow the instructions found in this Handbook, as well as the instructions of the Felony Drug Court Judge, Staff, and Treatment Provider. You will also be expected to comply with the treatment plan developed for you by your Treatment Provider. This handbook is not exhaustive and there is no possible way to make it complete and detailed to answer every question or situation that arises.
    [Show full text]
  • Drug Detection Time Window Chart
    Chesapeake Toxicology Resources Drug Detection Windows Updated as of December, 15th 2014 The length of time that the presence of drugs of abuse in the body can be detected is an important factor in drug screening. The chart below outlines approximate duration times. When interpreting the duration for the presence of drugs of abuse in the body, you must take into consideration variables including the body's metabolism, the subject's physical condition, overall body fluid balance, state of hydration and frequency of usage. Amphetamines Drug Name Metabolite Detection Window Prescription Names Amphetamine 3-5 Days Adderall, Adderall XR, Dexedrine, Spansule, DextroStat MDA 2-5 Days Tenamfetamine MDMA MDA 1-3 Days Adam, Ecstacy Methamphetamine Amphetamine 3-5 Days Desoxyn, Desoxyn Gradument Anti-epileptics Drug Name Metabolite Detection Window Prescription Names Gabapentin 1-5 Days Neurontin, Nupentin, Fanatrex, Gabarone, Gralise Pregablin 1-4 Days Lyrica CHESAPEAKE TOXICOLOGY RESOURCES- DRUG DETECTION TIMETABLE !1 Barbiturates Drug Name Metabolite Detection Window Prescription Names Amobarbital 2-10 Days Amytal, Amylobarbiton, Tuinal Butalbital 4-6 Days Axocet, Axotal, Bucet, Bupap, Butex Forte, Cephadyn, Dolgic, Esgic, Esgic-Plus, Fioricet, Fiorinal, Fiormor, Fiortal, Fortabs, Laniroif, Margesic, Marten-Tab, Medigesic, Phrenilin, Phrenilin Forte, Repan, Sedapap, Tencon, Triad Pentobarbital 2-10 Days Euthasol, Nembutal , Nembutal Sodium, Pentasol Phenobarbital Up to 16 days Antrocol, Barbidonna, Barbita, Bellacane, Bellatal, Bellergal-S, Chardonna-2,
    [Show full text]
  • Ce4less.Com Ce4less.Com Ce4less.Com Ce4less.Com Ce4less.Com Ce4less.Com Ce4less.Com
    Hallucinogens And Dissociative Drug Use And Addiction Introduction Hallucinogens are a diverse group of drugs that cause alterations in perception, thought, or mood. This heterogeneous group has compounds with different chemical structures, different mechanisms of action, and different adverse effects. Despite their description, most hallucinogens do not consistently cause hallucinations. The drugs are more likely to cause changes in mood or in thought than actual hallucinations. Hallucinogenic substances that form naturally have been used worldwide for millennia to induce altered states for religious or spiritual purposes. While these practices still exist, the more common use of hallucinogens today involves the recreational use of synthetic hallucinogens. Hallucinogen And Dissociative Drug Toxicity Hallucinogens comprise a collection of compounds that are used to induce hallucinations or alterations of consciousness. Hallucinogens are drugs that cause alteration of visual, auditory, or tactile perceptions; they are also referred to as a class of drugs that cause alteration of thought and emotion. Hallucinogens disrupt a person’s ability to think and communicate effectively. Hallucinations are defined as false sensations that have no basis in reality: The sensory experience is not actually there. The term “hallucinogen” is slightly misleading because hallucinogens do not consistently cause hallucinations. 1 ce4less.com ce4less.com ce4less.com ce4less.com ce4less.com ce4less.com ce4less.com How hallucinogens cause alterations in a person’s sensory experience is not entirely understood. Hallucinogens work, at least in part, by disrupting communication between neurotransmitter systems throughout the body including those that regulate sleep, hunger, sexual behavior and muscle control. Patients under the influence of hallucinogens may show a wide range of unusual and often sudden, volatile behaviors with the potential to rapidly fluctuate from a relaxed, euphoric state to one of extreme agitation and aggression.
    [Show full text]
  • Treatment Episode Data Set (TEDS) 2003 - 2013
    Treatment Episode Data Set (TEDS) 2003 - 2013 National Admissions to Substance Abuse Treatment Services DEPARTMENT OF HEALTH AND HUMAN SERVICES Substance Abuse and Mental Health Services Administration ACKNOWLEDGMENTS This report was prepared for the Substance Abuse and Mental Health Services Administration (SAMHSA), U.S. Department of Health and Human Services (HHS), by Synectics for Management Decisions, Inc. (Synectics), Arlington, Virginia. Work by Synectics was performed under Task Order HHSS283200700048I/HHSS28342001T, Reference No. 283-07-4803 (Cathie Alderks, Task Order Officer). PUBLIC DOMAIN NOTICE All material appearing in this report is in the public domain and may be reproduced or copied without permission from SAMHSA. Citation of the source is appreciated. However, this publication may not be reproduced or distributed for a fee without the specific, written authorization of the Office of Communications, SAMHSA, U.S. Department of Health and Human Services. RECOMMENDED CITATION Substance Abuse and Mental Health Services Administration, Center for Behavioral Health Statistics and Quality. Treatment Episode Data Set (TEDS): 2003-2013. National Admissions to Substance Abuse Treatment Services. BHSIS Series S-75, HHS Publication No. (SMA) 15-4934. Rockville, MD: Substance Abuse and Mental Health Services Administration, 2015. ELECTRONIC ACCESS AND COPIES OF PUBLICATION This publication may be downloaded or ordered at store.samhsa.gov. Or call SAMHSA at 1-877-SAMHSA-7 (1-877-726-4727) (English and Español). ORIGINATING OFFICE Center for Behavioral Health Statistics and Quality Substance Abuse and Mental Health Services Administration 1 Choke Cherry Road, Room 2-1084 Rockville, Maryland 20857 December 2015 ii TABLE OF CONTENTS List of Tables ...................................................................................................................................v List of Figures ..............................................................................................................................
    [Show full text]
  • Drugs of Abuseon September Archived 13-10048 No
    U.S. DEPARTMENT OF JUSTICE DRUG ENFORCEMENT ADMINISTRATION WWW.DEA.GOV 9, 2014 on September archived 13-10048 No. v. Stewart, in U.S. cited Drugs of2011 Abuse EDITION A DEA RESOURCE GUIDE V. Narcotics WHAT ARE NARCOTICS? Also known as “opioids,” the term "narcotic" comes from the Greek word for “stupor” and originally referred to a variety of substances that dulled the senses and relieved pain. Though some people still refer to all drugs as “narcot- ics,” today “narcotic” refers to opium, opium derivatives, and their semi-synthetic substitutes. A more current term for these drugs, with less uncertainty regarding its meaning, is “opioid.” Examples include the illicit drug heroin and pharmaceutical drugs like OxyContin®, Vicodin®, codeine, morphine, methadone and fentanyl. WHAT IS THEIR ORIGIN? The poppy papaver somniferum is the source for all natural opioids, whereas synthetic opioids are made entirely in a lab and include meperidine, fentanyl, and methadone. Semi-synthetic opioids are synthesized from naturally occurring opium products, such as morphine and codeine, and include heroin, oxycodone, hydrocodone, and hydromorphone. Teens can obtain narcotics from friends, family members, medicine cabinets, pharmacies, nursing 2014 homes, hospitals, hospices, doctors, and the Internet. 9, on September archived 13-10048 No. v. Stewart, in U.S. cited What are common street names? Street names for various narcotics/opioids include: ➔ Hillbilly Heroin, Lean or Purple Drank, OC, Ox, Oxy, Oxycotton, Sippin Syrup What are their forms? Narcotics/opioids come in various forms including: ➔ T ablets, capsules, skin patches, powder, chunks in varying colors (from white to shades of brown and black), liquid form for oral use and injection, syrups, suppositories, lollipops How are they abused? ➔ Narcotics/opioids can be swallowed, smoked, sniffed, or injected.
    [Show full text]