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Assessing Non-Consensual Human Experimentation During the War on Terror
ACEVES_FINAL(DO NOT DELETE) 11/26/2018 9:05 AM INTERROGATION OR EXPERIMENTATION? ASSESSING NON-CONSENSUAL HUMAN EXPERIMENTATION DURING THE WAR ON TERROR WILLIAM J. ACEVES* The prohibition against non-consensual human experimentation has long been considered sacrosanct. It traces its legal roots to the Nuremberg trials although the ethical foundations dig much deeper. It prohibits all forms of medical and scientific experimentation on non-consenting individuals. The prohibition against non-consensual human experimentation is now well established in both national and international law. Despite its status as a fundamental and non-derogable norm, the prohibition against non-consensual human experimentation was called into question during the War on Terror by the CIA’s treatment of “high-value detainees.” Seeking to acquire actionable intelligence, the CIA tested the “theory of learned helplessness” on these detainees by subjecting them to a series of enhanced interrogation techniques. This Article revisits the prohibition against non-consensual human experimentation to determine whether the CIA’s treatment of detainees violated international law. It examines the historical record that gave rise to the prohibition and its eventual codification in international law. It then considers the application of this norm to the CIA’s treatment of high-value detainees by examining Salim v. Mitchell, a lawsuit brought by detainees who were subjected to enhanced interrogation techniques. This Article concludes that the CIA breached the prohibition against non-consensual human experimentation when it conducted systematic studies on these detainees to validate the theory of learned helplessness. Copyright © 2018 William J. Aceves *Dean Steven R. Smith Professor of Law at California Western School of Law. -
Recommendations to the Food and Drug Administration
RECOMMENDATIONS TO THE FOOD AND DRUG ADMINISTRATION FROM THE NATIONAL BLACK CHURCH INITIATIVE July 5, 2017 Honorable Dr. Scott Gottlieb, M.D. Commissioner U.S. Food and Drug Administration 10903 New Hampshire Avenue Silver Spring, MD 20993 Through: Church of God in Christ African Methodist Episcopal Church African Methodist Episcopal Zion Church Christian Methodist Episcopal Church Full Gospel Baptist Church Fellowship International National Baptist Convention, USA, Inc. National Baptist Convention of America, Inc. Progressive National Baptist Convention, Inc. Pentecostal Assemblies of the World, Inc. The Union of Black Episcopalians National Council of Churches International Council of Community Churches Unity Fellowship Church Movement Mount Calvary Holy Churches of America Greater Mount Calvary Holy Church American Baptist Churches Berean Missionary Baptist Church The Potter’s House Dear Honorable Dr.Gottlieb, Congratulations on your appointment as the Commissioner of the FDA. We are extremely pleased that you are willing to meet with us and consider recommendations of increasing African Americans in clinical trials. Let us pledge our entire support of 34,000 Black Churches behind your agenda during your tenure. We are committed to helping to produce safe and effective drugs, nutritious and disease-free food, and innovation in the process of these two industries that are now under your regulatory control. We are committed to making your tenure the most successful in the history of the FDA. Five years ago, the National Black Church Initiative Board and Denominational Leadership decided we needed to be a part of the coalition to improve our nation’s health after the passing of the Affordable Care Act. -
The Logic & Legitimacy of American Bioethics at The
Doing the Right Thing: The Logic & Legitimacy of American Bioethics at the turn of the Millennium Item Type text; Electronic Dissertation Authors Leinhos, Mary Rebecca Publisher The University of Arizona. Rights Copyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author. Download date 02/10/2021 11:11:58 Link to Item http://hdl.handle.net/10150/193799 DOING THE RIGHT THING: THE LOGIC & LEGITIMACY OF AMERICAN BIOETHICS AT THE TURN OF THE MILLENNIUM by Mary Rebecca Leinhos ________________________ A Dissertation Submitted to the Faculty of the DEPARTMENT OF HIGHER EDUCATION In Partial Fulfillment Of The Requirements For the Degree of DOCTOR OF PHILOSOPHY In the Graduate College THE UNIVERSITY OF ARIZONA 2006 2 THE UNIVERSITY OF ARIZONA GRADUATE COLLEGE As members of the Dissertation Committee, we certify that we have read the dissertation prepared by Mary Rebecca Leinhos entitled Doing the Right Thing: The Logic & Legitimacy of American Bioethics at the Turn of the Millennium and recommend that it be accepted as fulfilling the dissertation requirement for the Degree of Doctor of Philosophy in Higher Education _____________________________________________________Date: Nov. 21, 2005 Jennifer Croissant _____________________________________________________Date: Nov. 21, 2005 Sheila Slaughter _____________________________________________________Date: Nov. 21, 2005 Gary Rhoades Final approval and acceptance of this dissertation is contingent upon the candidate’s submission of the final copies of the dissertation to the Graduate College. I hereby certify that I have read this dissertation prepared under my direction and recommend that it be accepted as fulfilling the dissertation requirement. -
Phrecord Summer 2017
Physicians for Human Rights PHRecord Summer 2017 You Helped Us Tell the Truth about What Killed the People of Khan Sheikhoun When the bombs descended upon the victims, many of them children. “It looked chemical attack occur. We know that PHR’s Syrian town of Khan Sheikhoun in the like people were struggling against death. deep bench and known voice will have an early hours of April 4, Physicians for They were resisting death.” impact – that by exposing these war crimes, Human Rights’ Syria team sprang into by calling out the perpetrators, and by action. As hundreds of Syrian men, PHR’s medical experts analyzed first-hand drawing the world’s attention when human women, and children were overwhelmed reports from medical personnel on the rights are so cruelly violated, we can help by an apparent chemical weapons attack ground and video and photographic deter abuses and ensure justice in the future. and hospitals were overrun with the dying, documentation of victims. Within hours, Thank you for making that possible. PHR’s researchers quickly reached out PHR was able to state that the attack had to our network of health and emergency all the hallmarks of an assault with a nerve workers across Idlib Governorate to try to agent – and we were cited again and again understand what was happening. in the global media. Bashar, a first responder with the Syrian Your backing has enabled PHR to develop Civil Defense – the White Helmets – told a deep expertise in chemical weapons, PHR researcher Racha Mouawieh that the supported our extensive documentation attack was unlike anything he had ever of attacks on health care, and nurtured our encountered. -
Dissemination of Vaccine Misinformation on Twitter and Its Countermeasures
Dissertation Dissemination of Vaccine Misinformation on Twitter and Its Countermeasures Christine Chen This document was submitted as a dissertation in March 2021 in partial fulfillment of the requirements of the doctoral degree in public policy analysis at the Pardee RAND Graduate School. The faculty committee that supervised and approved the dissertation consisted of Luke Matthews (Chair), Sarah Nowak and Jeremy Miles. The external reader was Jennifer Golbeck. This dissertation was generously supported by the Anne and James Rothenberg Dissertation Award. PARDEE RAND GRADUATE SCHOOL For more information on this publication, visit http://www.rand.org/pubs/rgs_dissertations/RGSDA1332-1.html Published 2021 by the RAND Corporation, Santa Monica, Calif. is a registered trademarK Limited Print and Electronic Distribution Rights This document and trademarK(s) contained herein are protected by law. This representation of RAND intellectual property is provided for noncommercial use only. Unauthorized posting of this publication online is prohibited. Permission is given to duplicate this document for personal use only, as long as it is unaltered and complete. Permission is reQuired from RAND to reproduce, or reuse in another form, any of its research documents for commercial use. For information on reprint and linking permissions, please visit www.rand.org/pubs/permissions.html. The RAND Corporation is a research organization that develops solutions to public policy challenges to help maKe communities throughout the world safer and more secure, healthier and more prosperous. RAND is nonprofit, nonpartisan, and committed to the public interest. RAND’s publications do not necessarily reflect the opinions of its research clients and sponsors. Support RAND MaKe a tax-deductible charitable contribution at www.rand.org/giving/contribute www.rand.org Abstract Outbreaks of vaccine preventable diseases have continued to affect many parts of the United States. -
Nuremberg Code: Why It’S Important
UC DAVIS OFFICE OF RESEARCH Nuremberg Code: Why it’s Important Miles McFann IRB Administration Outreach and Training Nuremberg Trial 1946 -1947: “Doctors’ Trial” 23 defendants • 22 men • 1 woman 16 convictions • 9 prison sentences • 7 death sentences War Crimes: • Performing medical experimentation without subjects consent • Experimentation led to permanent disfigurement, disability, and/or death • Experimentation conducted on vulnerable populations 2 Nuremberg Trial (cont.) The Hippocratic Oath on Trial? 3 Nuremberg Code 1. The voluntary consent of the human subject is absolutely essential. • Ethical Principal: Respect for Persons 2. The experiment should be such as to yield fruitful results for the good of society, unprocurable by other methods or means of study, and not random and unnecessary in nature. • Ethical Principal: Beneficence 3. The experiment should be so designed and based on the results of animal experimentation and a knowledge of the natural history of the disease or other problem under study, that the anticipated results will justify the performance of the experiment. • Ethical Principal: Beneficence 4. The experiment should be so conducted as to avoid all unnecessary physical and mental suffering and injury. • Ethical Principal: Beneficence 4 Nuremberg Code 5. No experiment should be conducted, where there is an a priori reason to believe that death or disabling injury will occur; except, perhaps, in those experiments where the experimental physicians also serve as subjects. • Ethical Principal: Beneficence, Justice 6. The degree of risk to be taken should never exceed that determined by the humanitarian importance of the problem to be solved by the experiment. • Ethical Principal: Beneficence 7. Proper preparations should be made and adequate facilities provided to protect the experimental subject against even remote possibilities of injury, disability, or death. -
Protecting Human Research Participants NIH Office of Extramural Research Introduction
Protecting Human Research Participants NIH Office of Extramural Research Introduction Research with human subjects can occasionally result in a dilemma for investigators. When the goals of the research are designed to make major contributions to a field, such as improving the understanding of a disease process or determining the efficacy of an intervention, investigators may perceive the outcomes of their studies to be more important than providing protections for individual participants in the research. Although it is understandable to focus on goals, our society values the rights and welfare of individuals. It is not considered ethical behavior to use individuals solely as means to an end. The importance of demonstrating respect for research participants is reflected in the principles used to define ethical research and the regulations, policies, and guidance that describe the implementation of those principles. Who? This course is intended for use by individuals involved in the design and/or conduct of National Institutes of Health (NIH) funded human subjects research. What? This course is designed to prepare investigators involved in the design and/or conduct of research involving human subjects to understand their obligations to protect the rights and welfare of subjects in research. The course material presents basic concepts, principles, and issues related to the protection of research participants. Why? As a part of NIH's commitment to the protection of human subjects and its response to Federal mandates for increased emphasis on protection for human subjects in research, the NIH Office of Extramural Research released a policy on Required Education in the Protection of Human Research Participants in June 2000. -
Revised Ethical Guidelines in Indian Biobanking
Revised Ethical Guidelines In Indian Biobanking: Do We Need To Downregulate the Proposed Frameworks? Juhi Tayal1, Anurag Mehta2 and Alok Kumar1 1 Biorepository, Department of Research, Rajiv Gandhi Cancer Institute and Research Centre, India 2 Department of Laboratory Sciences and Molecular Diagnostics, RGCI&RC, India 1,2 Sec-5,Rohini, New Delhi, India-110085 Email: [email protected]/ [email protected] BACKGROUND Guideline for Indian Biobanks ABSTRACT • Clinical biobanks are gaining popularity in India and are also revolutionizing research. Indian • Biomedical research in India has revolutionized with the changing times. This Council for Medical Research(ICMR),Council for Scientific and Industrial Research (CSIR) and paradigm shift has not only bought greater complexities but also greater Department of Biotechnology (DBT) are the major agencies supporting research in India. The ICMR responsibilities for policy makers ,researchers and stakeholders. The is the national organization and also the apex body for developing ethical frameworks and guidelines advancement is not limited to basic research or clinical research ,it has now and also enforcing them. The ICMR issued the Policy Statement on Ethical Considerations Involved taken a foothold into Digital imaging and Artificial intelligence platforms as in Research on Human Subjects in 1980. Due to rapid advancement in biomedical sciences new well. ethical dimensions have emerged and nesseciated the updation of these guidelines time and again in • The aim of policy makers worldover was to safeguard four basic ethical 2000,2003, 2013 and very recently in 2017. The revision has introduced many new sections and principles for research involving human subjects: respect for persons, also revamped the existing sections .A new Section 11 was dedicated to Biological materials, beneficence, non-maleficence and justice. -
The Ethics of Social Research
03-HesseBiber-4725.qxd 5/25/2005 7:53 PM Page 83 CHAPTER 3 THE ETHICS OF SOCIAL RESEARCH THE TUSKEGEE SYPHILIS STUDY The Tuskegee Syphilis Study was conducted by the United States Public Health Service (USPHS) beginning in 1932. The study examined untreated cases of latent syphilis in human subjects to determine the “natural course” of the disease. Three hundred and ninety nine black males from Tuskegee, Alabama, who already had late-stage syphilis, were recruited for this study along with a matched sample of 201 noninfected males. The subjects were not asked to provide their informed consent in order to participate in this project. Those infected with syphilis in the early 1930s were given the stan- dard treatment at that time, which consisted of administering heavy metals. However, those men participating in the study were, not treated. In fact, the doctor in charge of the study noted “everyone is agreed that the proper pro- cedure is the continuance of the observation of the negro men used in the study with the idea of eventually bringing them to autopsy” (Jones, 1993, p. 132). However, when antibiotics became available in the 1940s and it was evident that this treatment would improve a patient’s chances for recovery, antibiotic treatment was withheld from the infected subjects, even though the researchers knew that if left untreated the disease would definitely progress to increased disability and eventually early death. According to some reports, “on several occasions, the USPHS actually sought to pre- vent treatment” (Heintzelman, 1996, p. 49). The experiment lasted over four decades, and it was not until 1972, in large part prompted by exposure from 83 03-HesseBiber-4725.qxd 5/25/2005 7:53 PM Page 84 84–●–THE QUALITATIVE PARADIGM the national media, that government officials finally ended the experiment. -
Download Printable Issue (PDF)
S T A N F O R D MEDICINEMED Spring 2011 special report BIOETHICS NO EASY ANSWERS At midlife Ethicists roll up their sleeves Who will buy? Phony stem cell treatments for sale Gender X Born ambiguous Dead or alive? The tipping point between patient and organ donor Jesse’s legacy A conversation with Paul Gelsinger 11 years after his son’s death S T A N F O R D MEDICINE Spring 2011 high-res head shot A NEW WAy to see the brain’s connections It’s mind-boggling. A typical human brain contains about 200 billion neurons linked to one another via hundreds of trillions of tiny connections called synapses. These connections form the circuits behind thinking, feeling and moving — yet they’re so abundant and closely packed that getting a precise handle on what’s where has defied scientists’ best attempts. • But here comes a solution. Stephen Smith, PhD, professor of molecular and cellular physiology, and Kristina Micheva, PhD, a senior staff scientist in Smith’s lab, have invented a technique that quickly locates and counts the synapses in unprecedented detail, and reveals their variations. They described the imaging system, called “array tomography,” in the Nov. 18, 2010, issue of Neuron. • Attempting to map the cerebral cortex’s complex circuitry has been a fool’s errand up to now, Smith says. “We’ve been guessing at it.” Synapses in the brain are crowded so close together that they cannot be reliably resolved by even the best of traditional light microscopes, he says. • In particular, the cerebral cortex — a thin layer of tissue on the brain’s surface — is a thicket of prolifically branching neurons. -
Tissue Augmentation in Clinical Practice
Tissue Augmentation in Clinical Practice DDK1223_FM.inddK1223_FM.indd 1 110/12/050/12/05 88:45:28:45:28 AAMM PProcessrocess CCyanyanPProcessrocess MMagentaagentaPProcessrocess YYellowellowPProcessrocess BBlacklack BASIC AND CLINICAL DERMATOLOGY Series Editors ALAN R. SHALITA, M.D. Distinguished Teaching Professor and Chairman Department of Dermatology SUNY Downstate Medical Center Brooklyn, New York DAVID A. NORRIS, M.D. Director of Research Professor of Dermatology The University of Colorado Health Sciences Center Denver, Colorado 1. Cutaneous Investigation in Health and Disease: Noninvasive Methods and Instrumentation, edited by Jean-Luc Lévêque 2. Irritant Contact Dermatitis, edited by Edward M. Jackson and Ronald Goldner 3. Fundamentals of Dermatology: A Study Guide, Franklin S. Glickman and Alan R. Shalita 4. Aging Skin: Properties and Functional Changes, edited by Jean-Luc Lévêque and Pierre G. Agache 5. Retinoids: Progress in Research and Clinical Applications, edited by Maria A. Livrea and Lester Packer 6. Clinical Photomedicine, edited by Henry W. Lim and Nicholas A. Soter 7. Cutaneous Antifungal Agents: Selected Compounds in Clinical Practice and Development, edited by John W. Rippon and Robert A. Fromtling 8. Oxidative Stress in Dermatology, edited by Jürgen Fuchs and Lester Packer 9. Connective Tissue Diseases of the Skin, edited by Charles M. Lapière and Thomas Krieg 10. Epidermal Growth Factors and Cytokines, edited by Thomas A. Luger and Thomas Schwarz 11. Skin Changes and Diseases in Pregnancy, edited by Marwali Harahap and Robert C. Wallach 12. Fungal Disease: Biology, Immunology, and Diagnosis, edited by Paul H. Jacobs and Lexie Nall 13. Immunomodulatory and Cytotoxic Agents in Dermatology, edited by Charles J. McDonald 14. -
The Charlie Gard Case: British and American Approaches to Court Resolution of Disputes Over Medical Decisions
OPEN Journal of Perinatology (2017) 37, 1268–1271 www.nature.com/jp COMMENTARY The Charlie Gard case: British and American approaches to court resolution of disputes over medical decisions JJ Paris1,2, J Ahluwalia3, BM Cummings4, MP Moreland5 and DJ Wilkinson6,7 Journal of Perinatology (2017) 37, 1268–1271; doi:10.1038/jp.2017.138; United States identified by the court as ‘Dr I.’ To finance the published online 19 October 2017 treatment the parents raised £1.3 million. The disagreement between the parents and the physicians in this case was not about cost, it was whether or not the experimental therapy ought to be tried on Charlie. The parents wanted it done. The physicians were For those whose bodies are riddled with disease, [Aclepius] opposed. They believed that continued intensive care and the did not attempt to prescribe a regimen in order to make proposed nucleoside treatment were ‘futile.’ their life a prolonged misery. Medicine isn’t intended for A British Court was petitioned to approve an order ‘that it is ’ fi such people ... even if they are richer than Midas. lawful, and in Charlie s best interests, for arti cial ventilation to be Plato, The Republic, Bk III. withdrawn ... and for his treating clinicians to provide him with palliative care only.’ The request was a direct challenge to the parent’s hopes. The case was assigned to Mr Justice Francis of the Family Division INTRODUCTION of the High Court. The judge made clear from the outset that ‘This ’ ‘ On 8 June 2017, the Supreme Court in the United Kingdom case is not about money.