PLCG1 Monoclonal Antibody, Clone FAA-16

PLCG1 monoclonal antibody, clone Gene Symbol: PLCG1

FAA-16 Gene Alias: PLC-II, PLC1, PLC148, PLCgamma1

Catalog Number: MAB20604 Gene Summary: The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate Regulatory Status: For research use only (RUO) and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a Product Description: Rabbit monoclonal antibody cofactor and plays an important role in the intracellular raised against synthetic peptide of human PLCG1. transduction of receptor-mediated tyrosine kinase Clone Name: FAA-16 activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide Immunogen: A synthetic peptide corresponding to exchange factor RasGRP1 to translocate to the Golgi, human PLCG1. where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding Host: Rabbit growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding Reactivity: Human different isoforms have been found for this gene. [provided by RefSeq] Applications: ICC, IF, IP, WB-Ce (See our web site product page for detailed applications information)

Protocols: See our web site at http://www.abnova.com/support/protocols.asp or product page for detailed protocols

Form: Liquid

Purification: Affinity purification

Isotype: IgG

Recommend Usage: Immunocytochemistry (1:50-1:200) Immunofluorescence (1:50-1:200) Immunoprecipitation (1:50) Western Blot (1:1000-1:5000) The optimal working dilution should be determined by the end user.

Storage Buffer: In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).

Storage Instruction: Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Entrez GeneID: 5335

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