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PARP1
The Role of PARP1 in Monocyte and Macrophage
Poly(ADP-Ribose) Polymerase-1 (PARP1) and P53 Labelling Index Correlates with Tumour Grade in Meningiomas
PARP Inhibitors in Prostate Cancer–The Preclinical Rationale and Current Clinical Development
A Review of the Recent Advances Made with SIRT6 and Its Implications on Aging Related Processes, Major Human Diseases, and Possible Therapeutic Targets
P53-Dependent Cell Cycle Checkpoint After DNA Damage and Its
Inhibition of Helicase Activity by a Small Molecule Impairs Werner Syndrome Helicase (WRN) Function in the Cellular Response to DNA Damage Or Replication Stress
The PARP Inhibitor Olaparib Modulates the Transcriptional Regulatory Networks of Long Non-Coding Rnas During Vasculogenic Mimicry
Predictive Biomarkers for Cancer Therapy with PARP Inhibitors
PARP1-Mediated Necrosis Is Dependent on Parallel JNK and Ca
NF-Kb and Poly (ADP-Ribose) Polymerase 1 Form a Positive
Review Research
Werner Syndrome: Clinical Features, Pathogenesis and Potential Therapeutic Interventions
PGC-1Α, Sirtuins and Parps in Huntington's Disease and Other
MACROD2 Haploinsufficiency Impairs Catalytic Activity of PARP1 and Promotes Chromosome Instability and Growth of Intestinal Tumors
PARP Traps Rescue the Pro-Inflammatory Response Of
SIRT1/PARP1 Crosstalk: Connecting DNA Damage and Metabolism Augustin Luna1,2*, Mirit I Aladjem1 and Kurt W Kohn1
PARP1 in Carcinomas and PARP1 Inhibitors As Antineoplastic Drugs
Nonhomologous End Joining Drives Poly(ADP-Ribose) Polymerase (PARP) Inhibitor Lethality in Homologous Recombination-Deficient Cells
Top View
PARP Inhibitors: Extending Benefit Beyond BRCA-Mutant Cancers
Poly(ADP-Ribose) Polymerase Activation Induces High Mobility Group Box 1 Release from Proximal Tubular Cells During Cisplatin Nephrotoxicity
Polymerase Inhibition on DNA Break Repair in Human Cells Are Revealed with Epstein–Barr Virus
PARP1 Promotes Gene Expression at the Post-Transcriptiona Level By
Review Research
PARP Power: a Structural Perspective on PARP1, PARP2, and PARP3 in DNA Damage Repair and Nucleosome Remodelling
PARP1 Regulates the Protein Stability and Proapoptotic Function of HIPK2
Poly(ADP-Ribose) Polymerase 1 Searches DNA Via a 'Monkey Bar
The Molecular Mechanism of PARP1 Activation and Its Downstream Roles in ALC1-Regulated Transcription
FAF1 Mediates Regulated Necrosis Through PARP1 Activation Upon Oxidative Stress Leading to Dopaminergic Neurodegeneration
The Antiviral Activities of Poly-ADP-Ribose Polymerases
PARP1 Regulates DNA Damage-Induced Nucleolar-Nucleoplasmic Shuttling of WRN and XRCC1 in a Toxicant and Protein-Specific Manner
Response of Breast Cancer Cells to PARP Inhibitors Is Independent of BRCA Status
The Role of ADP-Ribose Metabolism in Metabolic Regulation, Adipose Tissue Differentiation, and Metabolism
PARP1 Inhibition Augments UVB-Mediated Mitochondrial Changes—Implications for UV-Induced DNA Repair and Photocarcinogenesis
Targeted Deletion of P53 in the Proximal Tubule Prevents Ischemic Renal Injury
Exploiting DNA Damage Repair in Precision Cancer Therapy: BRCA1 As a Prime Therapeutic Target
PARP1 Expression, Activity and Ex Vivo Sensitivity to the PARP Inhibitor, Talazoparib (BMN 673), in Chronic Lymphocytic Leukaemia
Multifaceted Role of PARP-1 in DNA Repair and Inflammation
Adenoviral Vectors for Modulation of Poly(ADP-Ribose) Polymerase-1 (PARP1) – Dependent DNA Repair As a Predictive Tool for Chemotherapy
Polymerase 1 Transcriptional Regulation: a Novel Crosstalk Between Histone Modification H3k9ac and ETS1 Motif Hypomethylation in BRCA1-Mutated Ovarian Cancer
Gain-Of-Function Mutant P53 R273H Interacts with Replicating DNA and PARP1 in Breast Cancer
Identification of PARP-1, Histone H1 and SIRT-1 As New Regulators Of
P53 Loss Mediates Hypersensitivity to ETS Transcription Factor Inhibition Based on Parylation-Mediated Cell Death Induction
The PARP Way to Epigenetic Changes
Poly Adp Ribose Polymerase and the Therapeutic Effects of Its Inhibitors
C-Abl–Mediated Tyrosine Phosphorylation of PARP1 Is Crucial for Expression of Proinflammatory Genes
Haploinsufficiency of Parp1 Accelerates Brca1- Associated
The Impact of Parps and ADP-Ribosylation on Inflammation and Host–Pathogen Interactions
Of HMGB1 Acetylation Release by Macrophages Through Regulation
PARP1-Driven Poly-ADP-Ribosylation Regulates BRCA1 Function in Homologous Recombination–Mediated DNA Repair
The Role of PARP in DNA Repair and Its Therapeutic Exploitation
Synthetic Lethality Vs. Synthetic Viability Due to PARP1 and BRCA2 Loss
Analysis of PARP Inhibitor Toxicity by Multidimensional fluorescence Microscopy Reveals Mechanisms of Sensitivity and Resistance
Poly(ADP-Ribose) Polymerase 1–Sirtuin 1 Functional Interplay Regulates LPS-Mediated High Mobility Group Box 1 Secretion
Ets-1 Interacts Through a Similar Binding Interface with Ku70 and Poly
Chromatin-Bound PARP1 Correlates with Upregulation of Inflammatory Genes in Response to Long-Term Treatment with Veliparib
Single-Molecule Measurements Reveal That PARP1 Condenses DNA by Loop Formation
PARP Inhibitor
PARP and PARG Inhibitors in Cancer Treatment
Aag-Initiated Base Excision Repair Promotes Ischemia Reperfusion
PARP1 Interacts with HMGB1 and Promotes Its Nuclear Export in Pathological Myocardial Hypertrophy