2011 DCN.Indd

Total Page:16

File Type:pdf, Size:1020Kb

2011 DCN.Indd MINNESOTA DEPARTMENT ISEASE ONTROL EWSLETTER OF HEALTH D C N Volume 39, Number 1 (pages 1-28) 2012 Annual Summary of Communicable Diseases Reported to the Minnesota Department of Health, 2011 Introduction Act (Section 13.38). Provisions of Incidence rates in this report were Assessment of the population’s the Health Insurance Portability and calculated using disease-specifi c health is a core public health function. Accountability Act (HIPAA) allow for numerator data collected by MDH and Surveillance for communicable routine disease reporting without a standardized set of denominator diseases is one type of assessment. patient authorization. data derived from U.S. Census data. Epidemiologic surveillance is the Disease incidence is categorized as systematic collection, analysis, and Since April 1995, MDH has participated occurring within the seven-county Twin dissemination of health data for as an Emerging Infections Program Cities metropolitan area (metropolitan the planning, implementation, and (EIP) site funded by the Centers area) or outside of it in Greater evaluation of health programs. The for Disease Control and Prevention Minnesota. Minnesota Department of Health (CDC) and, through this program, (MDH) collects information on has implemented active hospital- and Anaplasmosis certain infectious diseases for the laboratory-based surveillance for Human anaplasmosis (formerly purposes of determining disease several conditions, including selected known as human granulocytic impact, assessing trends in disease invasive bacterial diseases, foodborne ehrlichiosis) is caused by Anaplasma occurrence, characterizing affected diseases, and hospitalized infl uenza phagocytophilum, a rickettsial organism populations, prioritizing control efforts, cases. transmitted to humans by bites from and evaluating prevention strategies. Ixodes scapularis (the blacklegged Prompt reporting allows outbreaks to Isolates for pathogens with certain tick or deer tick). In Minnesota, the be recognized in a timely fashion when diseases are required to be submitted same tick vector also transmits the control measures are most likely to be to MDH (Table 1). The MDH Public etiologic agents of Lyme disease, effective in preventing additional cases. Health Laboratory (PHL) performs babesiosis, one form of human microbiologic evaluation of isolates, ehrlichiosis, and a strain of Powassan In Minnesota, communicable disease such as pulsed-fi eld gel electrophoresis virus. A. phagocytophilum can also be reporting is centralized, whereby (PFGE), to determine whether isolates transmitted by blood transfusion. reporting sources submit standardized (e.g., enteric pathogens such as report forms to MDH. Cases of disease Salmonella and Escherichia coli In 2011, a record number of 782 are reported pursuant to Minnesota O157:H7, and invasive pathogens confi rmed or probable anaplasmosis Rules Governing Communicable such as Neisseria meningitidis) are cases (14.7 cases per 100,000 Diseases (Minnesota Rules 4605.7000 related, and potentially associated with population) were reported (Figure 1). - 4605.7800). The diseases listed in a common source. Testing of submitted The median number of 298 cases Table 1 (page 2) must be reported isolates also allows detection and (range, 139 to 782 cases) reported to MDH. As stated in the rules, monitoring of antimicrobial resistance, from 2004 through 2011 is also physicians, health care facilities, which continues to be an important continued on page 4 laboratories, veterinarians, and others problem (see pp. 26-27). are required to report these diseases. Reporting sources may designate Table 2 summarizes cases of selected an individual within an institution communicable diseases reported to perform routine reporting duties during 2011 by district of the patient’s (e.g., an infection preventionist for a residence. Pertinent observations for Inside: hospital). Data maintained by MDH some of these diseases are presented are private and protected under the below. Antimicrobial Susceptibilities of Minnesota Government Data Practices Selected Pathogens, 2011...........26 Table 1. Diseases Reportable to the Minnesota Department of Health Report Immediately by Telephone Anthrax (Bacillus anthracis) a Q fever (Coxiella burnetii) a Botulism (Clostridium botulinum) Rabies (animal and human cases and suspected cases) Brucellosis (Brucella spp.) a Rubella and congenital rubella syndrome a Cholera (Vibrio cholerae) a Severe Acute Respiratory Syndrome (SARS) Diphtheria (Corynebacterium diphtheriae) a (1. Suspect and probable cases of SARS. 2. Cases of health Hemolytic uremic syndrome a care workers hospitalized for pneumonia or acute respiratory Measles (rubeola) a distress syndrome.) a Meningococcal disease (Neisseria meningitidis) Smallpox (variola) a (all invasive disease) a, b Tularemia (Francisella tularensis) a Orthopox virus a Unusual or increased case incidence of any suspect Plague (Yersinia pestis) a infectious illness a Poliomyelitis a Report Within One Working Day Amebiasis (Entamoeba histolytica/dispar) Malaria (Plasmodium spp.) Anaplasmosis (Anaplasma phagocytophilum) Meningitis (caused by viral agents) Arboviral disease (including but not limited to, Mumps LaCrosse encephalitis, eastern equine encephalitis, western Neonatal sepsis, less than 7 days after birth (bacteria isolated from equine encephalitis, St. Louis encephalitis, and a sterile site, excluding coagulase-negative West Nile virus) Staphylococcus) a, b Babesiosis (Babesia spp.) Pertussis (Bordetella pertussis) a Blastomycosis (Blastomyces dermatitidis) Psittacosis (Chlamydophila psittaci) Campylobacteriosis (Campylobacter spp.) a Retrovirus infection Cat scratch disease (infection caused by Bartonella spp.) Reye syndrome Chancroid (Haemophilus ducreyi) c Rheumatic fever (cases meeting the Jones Criteria only) Chlamydia trachomatis infection c Rocky Mountain spotted fever (Rickettsia rickettsii, R. canada) Coccidioidomycosis Salmonellosis, including typhoid (Salmonella spp.) a Cryptosporidiosis (Cryptosporidium spp.) a Shigellosis (Shigella spp.) a Cyclosporiasis (Cyclospora spp.) a Staphylococcus aureus (vancomycin-intermediate S. aureus [VISA], Dengue virus infection vancomycin-resistant S. aureus [VRSA], and death or critical Diphyllobothrium latum infection illness due to community-associated S. aureus in a previously Ehrlichiosis (Ehrlichia spp.) healthy individual) a Encephalitis (caused by viral agents) Streptococcal disease (all invasive disease caused by Groups A Enteric E. coli infection (E. coli O157:H7, other enterohemorrhagic and B streptococci and S. pneumoniae) a, b [Shiga toxin-producing] E. coli, enteropathogenic E. coli, Syphilis (Treponema pallidum) c enteroinvasive E. coli, enterotoxigenic E. coli) a Tetanus (Clostridium tetani) Enterobacter sakazakii (infants under 1 year of age) a Toxic shock syndrome a Giardiasis (Giardia lamblia) Toxoplasmosis (Toxoplasma gondii) Gonorrhea (Neisseria gonorrhoeae) c Transmissible spongiform encephalopathy Haemophilus infl uenzae disease (all invasive disease) a,b Trichinosis (Trichinella spiralis) Hantavirus infection Tuberculosis (Mycobacterium tuberculosis complex) (Pulmonary or Hepatitis (all primary viral types including A, B, C, D, and E) extrapulmonary sites of disease, including laboratory Histoplasmosis (Histoplasma capsulatum) confi rmed or clinically diagnosed disease, are reportable. Human immunodefi ciency virus (HIV) infection, including Latent tuberculosis infection is not reportable.) a Acquired Immunodefi ciency Syndrome (AIDS) a, d Typhus (Rickettsia spp.) Infl uenza (unusual case incidence, critical illness, or laboratory Unexplained deaths and unexplained critical illness confi rmed cases) a (possibly due to infectious cause) a Kawasaki disease Varicella-zoster disease Kingella spp. (invasive only) a, b (1. Primary [chickenpox]: unusual case incidence, critical Legionellosis (Legionella spp.) a illness, or laboratory-confi rmed cases. 2. Recurrent [shingles]: Leprosy (Hansen’s disease) (Mycobacterium leprae) unusual case incidence, or critical illness.) a Leptospirosis (Leptospira interrogans) Vibrio spp. a Listeriosis (Listeria monocytogenes) a Yellow fever Lyme disease (Borrelia burgdorferi) Yersiniosis, enteric (Yersinia spp.) a Sentinel Surveillance (at sites designated by the Commissioner of Health) Methicillin-resistant Staphylococcus aureus a, b Clostridium diffi cile a Carbapenem-resistant Enterobacteriaceae spp. and carbapenem-resistant Acinetobacter spp. a a Submission of clinical materials required. If a rapid, non-culture assay is used b Isolates are considered to be from invasive disease if they are for diagnosis, we request that positives be cultured, and isolates submitted. If isolated from a normally sterile site, e.g., blood, CSF, joint fl uid, this is not possible, send specimens, nucleic acid, enrichment broth, or other etc. appropriate material. Call the MDH Public Health Laboratory at 651-201-4953 c Report on separate Sexually Transmitted Disease Report Card. for instructions. d Report on separate HIV Report Card. 2 DCN 39;1 2012 Table 2. Cases of Selected Communicable Diseases Reported to the Minnesota Department of Health by District of Residence, 2011 District (population per U.S. Census 2009 estimates) Metropolitan (2,810,414) Northwestern (153,218) Northeastern (320,342) Central (715,467) West Central (229,186) South Central (286,956) (486,517) Southeastern Southwestern (218,293) Disease Unknown Residence Total (5,220,393) Anaplasmosis 201 121 106 280 32 7 30 5 0 782 Arboviral
Recommended publications
  • Official Nh Dhhs Health Alert
    THIS IS AN OFFICIAL NH DHHS HEALTH ALERT Distributed by the NH Health Alert Network [email protected] May 18, 2018, 1300 EDT (1:00 PM EDT) NH-HAN 20180518 Tickborne Diseases in New Hampshire Key Points and Recommendations: 1. Blacklegged ticks transmit at least five different infections in New Hampshire (NH): Lyme disease, Anaplasma, Babesia, Powassan virus, and Borrelia miyamotoi. 2. NH has one of the highest rates of Lyme disease in the nation, and 50-60% of blacklegged ticks sampled from across NH have been found to be infected with Borrelia burgdorferi, the bacterium that causes Lyme disease. 3. NH has experienced a significant increase in human cases of anaplasmosis, with cases more than doubling from 2016 to 2017. The reason for the increase is unknown at this time. 4. The number of new cases of babesiosis also increased in 2017; because Babesia can be transmitted through blood transfusions in addition to tick bites, providers should ask patients with suspected babesiosis whether they have donated blood or received a blood transfusion. 5. Powassan is a newer tickborne disease which has been identified in three NH residents during past seasons in 2013, 2016 and 2017. While uncommon, Powassan can cause a debilitating neurological illness, so providers should maintain an index of suspicion for patients presenting with an unexplained meningoencephalitis. 6. Borrelia miyamotoi infection usually presents with a nonspecific febrile illness similar to other tickborne diseases like anaplasmosis, and has recently been identified in one NH resident. Tests for Lyme disease do not reliably detect Borrelia miyamotoi, so providers should consider specific testing for Borrelia miyamotoi (see Attachment 1) and other pathogens if testing for Lyme disease is negative but a tickborne disease is still suspected.
    [Show full text]
  • Case Definition for Non-Pestis Yersiniosis Check This Box If This Po
    19-ID-03 Committee: Infectious Disease Title: Case Definition for Non-pestis Yersiniosis ☒Check this box if this position statement is an update to an existing standardized surveillance case definition: 18-ID-02 Synopsis: This position statement updates the case definition for non-pestis yersiniosis through the clarification of laboratory criteria. I. Statement of the Problem Non-pestis yersiniosis is an infection caused most commonly by the bacteria Yersinia enterocolitica or Yersinia pseudotuberculosis. These bacteria are normal intestinal and oropharyngeal colonizers of swine, and most commonly cause infections in children under 10 years of age, or adults over 70 years of age, through contaminated food. After Salmonella, Shigella, Campylobacter, and Shiga-toxin producing E. coli, th it is the 5 most commonly reported gastrointestinal bacterial illness reported through CDC Foodborne Diseases Active Surveillance Network (FoodNet), which monitors 10 sites in the United States for nine enteric pathogens transmitted through food. The increasing use of culture-independent diagnostic tests (CIDTs) in all parts of clinical medicine, and particularly for gastrointestinal illnesses, has also increased recognition of certain pathogens. Data from 2016 from FoodNet show a 29% increase in culture-confirmed and a 91% increase in CIDT-diagnosed Yersinia infections when compared to the 2013-2015 time frame. Yersinia enterocolitica and/or Yersinia pseudotuberculosis infections are reportable in 38 states, but no standard national definition exists for confirmed and probable cases. This position statement proposes a standardized case definition for non-pestis yersiniosis. II. Background and Justification Yersinia enterocolitica and Yersinia pseudotuberculosis are Gram negative rod-shaped or coccoid organisms that can be isolated from many animals and are most often transmitted to humans from undercooked or contaminated pork.
    [Show full text]
  • Communicable Diseases Monthly Newsletter
    Communicable Diseases Monthly Newsletter October 2013 Volume 6, Issue 10 What is Pneumonia? neumonia is an infection of the lungs that is Inside This Issue P usually caused by bacteria or viruses. Globally, pneumonia causes more deaths than any 2 Pneumonia other infectious disease. It can often be prevented and can usually be treated. 2 Influenza Update Pneumonia can cause mild to severe illness in 3 people of all ages. Signs of pneumonia can include Communicable Diseases Report coughing, fever, fatigue, nausea, vomiting, rapid breathing or shortness of breath, chills, or chest pain. Certain people that are more likely to become ill with Rabies Awareness pneumonia include adults 65 years of age or older and children younger than 5 4 years. People with underlying medical conditions and those who smoke cigarettes or Sexually Transmitted have asthma are also at increased risk for pneumonia. Diseases Causes of Pneumonia When bacteria, viruses or, rarely, fungi living in your nose, mouth, sinuses, or the (Continued on page 2) Influenza update: 2013-2014 Season s of the week ending November 2, 2013, a total of 7 cases have been A reported in Joplin City (6) and Jasper County (1). Since the beginning of influenza reporting in October, influenza type A represents 85.7 percent of the cases (6 out of 7). This trend shows slightly less reports during the 2013-2014 season when compared with the previous season (2012-2013) within the same period. Influenza virus: Source: CDC.gov (Continued on page 2) Communicable Disease Monthly Newsletter Pneumonia (Continued from page 1) Reduce Your Risk environment spread to your lungs, you can develop Pneumonia can be prevented with vaccines.
    [Show full text]
  • Kellie ID Emergencies.Pptx
    4/24/11 ID Alert! recognizing rapidly fatal infections Susan M. Kellie, MD, MPH Professor of Medicine Division of Infectious Diseases, UNMSOM Hospital Epidemiologist UNMHSC and NMVAHCS Fever and…. Rash and altered mental status Rash Muscle pain Lymphadenopathy Hypotension Shortness of breath Recent travel Abdominal pain and diarrhea Case 1. The cross-country trucker A 30 year-old trucker driving from Oklahoma to California is hospitalized in Deming with fever and headache He is treated with broad-spectrum antibiotics, but deteriorates with obtundation, low platelet count, and a centrifugal petechial rash and is transferred to UNMH 1 4/24/11 What is your diagnosis? What is the differential diagnosis of fever and headache with petechial rash? (in the US) Tickborne rickettsioses ◦ RMSF Bacteria ◦ Neisseria meningitidis Key diagnosis in this case: “doxycycline deficiency” Key vector-borne rickettsioses treated with doxycycline: RMSF-case-fatality 5-10% ◦ Fever, nausea, vomiting, myalgia, anorexia and headache ◦ Maculopapular rash progresses to petechial after 2-4 days of fever ◦ Occasionally without rash Human granulocytotropic anaplasmosis (HGA): case-fatality<1% Human monocytotropic ehrlichiosis (HME): case fatality 2-3% 2 4/24/11 Lab clues in rickettsioses The total white blood cell (WBC) count is typicallynormal in patients with RMSF, but increased numbers of immature bands are generally observed. Thrombocytopenia, mild elevations in hepatic transaminases, and hyponatremia might be observed with RMSF whereas leukopenia
    [Show full text]
  • Iron Is an Essential Nutrient 4 Bacteria and Humans
    Abstract The bhuTUV and bhuO genes play vital roles in the ability of Brucella abortus to use heme as an iron source and are regulated in an iron-responsive manner by RirA and Irr by Jenifer F. Ojeda April, 2012 Dissertation Advisor: RM Roop II Department of Microbiology and Immunology Brucella abortus is a Gram negative intracellular pathogen that causes the zoonotic disease brucellosis. Antibiotic treatment for brucellosis in humans is prolonged and sometimes followed by relapses. Currently, the United States employs prevention of the illness in humans through cattle vaccinations, eliminating the bacterium in its natural host. Unfortunately, these vaccine strains cause the disease in humans, and Brucella research ultimately aims to identify new vaccine targets as well as alternative treatment options. Brucella abortus resides in the phagosomal compartment of the host macrophage where essential nutrients such as iron are limited. Most bacteria need iron, and within the macrophage, heme is a likely source of iron due to the breakdown of red blood cells by the host macrophage. Heme transporters in Gram negative bacteria are highly conserved, and include components for outer membrane, periplasmic, and cytoplasmic membrane transport. BhuA has been previously characterized as the outer membrane heme transporter of Brucella abortus and here we report that BhuT, BhuU, and BhuV (BhuTUV) are the periplasmic and cytoplasmic heme transport components and that they are required in order for Brucella abortus to transport heme as an iron source. Utilization of heme as an iron source requires the breakdown of heme into ferrous iron, carbon monoxide, and biliverdin by a heme oxygenase.
    [Show full text]
  • Weekly Epidemiologic L Report
    WEEKLY EPIDEMIOLOGICAL REPORT A publication of the Epidemiology Unit Ministry of Health 231, de Saram Place, Colombo 01000, Sri Lanka Tele: + 94 11 2695112, Fax: +94 11 2696583, E mail: [email protected] Epidemiologist: +94 11 2681548, E mail: [email protected] Web: http://www.epid.gov.lk Vol. 42 No. 33 08 th – 14 th August 2015 Melioidosis Key facts the area. People acquire the disease by inhaling dust contaminated by the bacteria and when the • Melioidosis is an infectious disease caused contaminated soil comes in contact with abraded by a bacterium, Burkholderia pseudomallei. (scraped) area of the skin. Infection most com- • Melioidosis infection commonly involves the monly occurs during the rainy season. lungs. Symptoms • Melioidosis is diagnosed with the help of Melioidosis symptoms most commonly stem blood, urine, sputum, or skin-lesion testing. from lung disease where the infection can form a • Melioidosis is treated with antibiotics. cavity of pus (abscess). The effects can range from mild bronchitis to severe pneumonia. As a • The overall mortality rate is 40%. result, patients also may experience fever, head- Introduction ache, loss of appetite, cough, chest pain, and general muscle soreness. Melioidosis, also called Whitmore's Disease, is an infectious disease caused by a bacterium The effects can also be localized to infection on called Burkholderia pseudomallei (previously the skin (cellulitis) with associated fever and muscle aches. It can spread from the skin known as Pseudomonas pseudomallei-Gram- negative,oxidase positive bacillus). The bacteria are found in contaminated water and soil and spread to humans and animals through direct contact with the contaminated source.
    [Show full text]
  • Reportable Diseases and Conditions
    KINGS COUNTY DEPARTMENT of PUBLIC HEALTH 330 CAMPUS DRIVE, HANFORD, CA 93230 REPORTABLE DISEASES AND CONDITIONS Title 17, California Code of Regulations, §2500, requires that known or suspected cases of any of the diseases or conditions listed below are to be reported to the local health jurisdiction within the specified time frame: REPORT IMMEDIATELY BY PHONE During Business Hours: (559) 852-2579 After Hours: (559) 852-2720 for Immediate Reportable Disease and Conditions Anthrax Escherichia coli: Shiga Toxin producing (STEC), Rabies (Specify Human or Animal) Botulism (Specify Infant, Foodborne, Wound, Other) including E. coli O157:H7 Scrombroid Fish Poisoning Brucellosis, Human Flavivirus Infection of Undetermined Species Shiga Toxin (Detected in Feces) Cholera Foodborne Disease (2 or More Cases) Smallpox (Variola) Ciguatera Fish Poisoning Hemolytic Uremic Syndrome Tularemia, human Dengue Virus Infection Influenza, Novel Strains, Human Viral Hemorrhagic Fever (Crimean-Congo, Ebola, Diphtheria Measles (Rubeola) Lassa, and Marburg Viruses) Domonic Acid Poisoning (Amnesic Shellfish Meningococcal Infections Yellow Fever Poisoning) Novel Virus Infection with Pandemic Potential Zika Virus Infection Paralytic Shellfish Poisoning Plague (Specify Human or Animal) Immediately report the occurrence of any unusual disease OR outbreaks of any disease. REPORT BY PHONE, FAX, MAIL WITHIN ONE (1) WORKING DAY Phone: (559) 852-2579 Fax: (559) 589-0482 Mail: 330 Campus Drive, Hanford 93230 Conditions may also be reported electronically via the California
    [Show full text]
  • Phenotypic and Genomic Analyses of Burkholderia Stabilis Clinical Contamination, Switzerland Helena M.B
    RESEARCH Phenotypic and Genomic Analyses of Burkholderia stabilis Clinical Contamination, Switzerland Helena M.B. Seth-Smith, Carlo Casanova, Rami Sommerstein, Dominik M. Meinel,1 Mohamed M.H. Abdelbary,2 Dominique S. Blanc, Sara Droz, Urs Führer, Reto Lienhard, Claudia Lang, Olivier Dubuis, Matthias Schlegel, Andreas Widmer, Peter M. Keller,3 Jonas Marschall, Adrian Egli A recent hospital outbreak related to premoistened gloves pathogens that generally fall within the B. cepacia com- used to wash patients exposed the difficulties of defining plex (Bcc) (1). Burkholderia bacteria have large, flexible, Burkholderia species in clinical settings. The outbreak strain multi-replicon genomes, a large metabolic repertoire, vari- displayed key B. stabilis phenotypes, including the inabil- ous virulence factors, and inherent resistance to many anti- ity to grow at 42°C; we used whole-genome sequencing to microbial drugs (2,3). confirm the pathogen was B. stabilis. The outbreak strain An outbreak of B. stabilis was identified among hos- genome comprises 3 chromosomes and a plasmid, shar- ing an average nucleotide identity of 98.4% with B. stabilis pitalized patients across several cantons in Switzerland ATCC27515 BAA-67, but with 13% novel coding sequenc- during 2015–2016 (4). The bacterium caused bloodstream es. The genome lacks identifiable virulence factors and has infections, noninvasive infections, and wound contamina- no apparent increase in encoded antimicrobial drug resis- tions. The source of the infection was traced to contaminat- tance, few insertion sequences, and few pseudogenes, ed commercially available, premoistened washing gloves suggesting this outbreak was an opportunistic infection by used for bedridden patients. After hospitals discontinued an environmental strain not adapted to human pathogenic- use of these gloves, the outbreak resolved.
    [Show full text]
  • Cutaneous Melioidosis Dermatology Section
    DOI: 10.7860/JCDR/2016/18823.8463 Case Report Cutaneous Melioidosis Dermatology Section BASAVAPRABHU ACHAPPA1, DEEPAK MADI2, K. VIDYALAKSHMI3 ABSTRACT Melioidosis is an emerging infection in India. It usually presents as pneumonia. Melioidosis presenting as cutaneous lesions is uncommon. We present a case of cutaneous melioidosis from Southern India. Cutaneous melioidosis can present as an ulcer, pustule or as crusted erythematous lesions. A 22-year-old gentleman known case of diabetes mellitus was admitted in our hospital with an ulcer over the left thigh. Discharge from the ulcer grew Burkholderia pseudomallei. He was successfully treated with ceftazidime. Melioidosis must be considered in the differential diagnosis of nodular or ulcerative cutaneous lesion in a diabetic patient. Keywords: B. pseudomallei, Diabetes Mellitus, Skin ulcer CASE REPORT melioidosis is a rare entity. Cutaneous melioidosis may be primary A 22-year-old gentleman was admitted in our hospital with (presenting symptom is skin infection) or secondary (melioidosis complaints of an ulcer over the left thigh of seven days duration. at other sites in the body with incidental skin involvement) [3]. History of fever was present for four days. He also complained of There is limited published data from India documenting cutaneous pain in the thigh. The patient initially noticed a nodule on the left melioidosis. thigh which eventually progressed to form a discharging ulcer. He B. pseudomallei reside in soil and water [4]. Inoculation, inhalation was a known case of diabetes mellitus (type 1) on insulin. Clinical or ingestion of infected food or water are the modes of transmission examination revealed a 5cm× 5cm ulcer on the left thigh with [5].
    [Show full text]
  • Necrotizing Fasciitis
    INFORMATION ABOUT NECROTIZING FASCIITIS • Information has been circulating on social media/media outlets of an individual who developed an infection after visiting our area. We are taking this issue seriously and are working with the Indiana Department of Health to determine if this infection was caused by bacteria such as Vibrio vulnificus or other reportable disease. Currently, we do not have any information about this individual’s illness. • Necrotizing fasciitis (many times called “flesh eating bacteria” by the media) is caused by more than one type of bacteria. Several bacteria, common in our environment can cause this condition – the most common cause of necrotizing fasciitis is Group A strep. • People do not “catch” necrotizing fasciitis; it is a complication or symptom of a bacterial infection that has not been promptly or properly treated. • Sometimes people call Vibrio vulnificus the “flesh eating bacteria.” Vibrio vulnificus is a naturally occurring bacteria found in warm salty waters such as the Gulf of Mexico and surrounding bays. Concentrations of this bacteria are higher when the water is warmer. • Necrotizing fasciitis and severe infections with Vibrio vulnificus are rare. These infections can be treated with antibiotics and sometimes require surgery to remove damaged tissue. Rapid diagnosis is the key to effective treatment and recovery. • If you are healthy with a strong immune system, your chances of developing or having complications due to this condition are extremely low. HOW TO REDUCE YOUR RISK OF EXPOSURE • The Centers for Disease Control and Prevention (CDC) encourages all people to avoid open bodies of water (such as the Gulf), pools and hot tubs with breaks in the skin.
    [Show full text]
  • 12. What's Really New in Antibiotic Therapy Print
    What’s really new in antibiotic therapy? Martin J. Hug Freiburg University Medical Center EAHP Academy Seminars 20-21 September 2019 Newsweek, May 24-31 2019 Disclosures There are no conflicts of interest to declare EAHP Academy Seminars 20-21 September 2019 Antiinfectives and Resistance EAHP Academy Seminars 20-21 September 2019 Resistance of Klebsiella pneumoniae to Pip.-Taz. olates) EAHP Academy Seminars 20-21 September 2019 https://resistancemap.cddep.org/AntibioticResistance.php Multiresistant Pseudomonas Aeruginosa Combined resistance against at least three different types of antibiotics, 2017 EAHP Academy Seminars 20-21 September 2019 https://atlas.ecdc.europa.eu/public/index.aspx Distribution of ESBL producing Enterobacteriaceae EAHP Academy Seminars 20-21 September 2019 Rossolini GM. Global threat of Gram-negative antimicrobial resistance. 27th ECCMID, Vienna, 2017, IS07 Priority Pathogens Defined by the World Health Organisation Critical Priority High Priority Medium Priority Acinetobacter baumanii Enterococcus faecium Streptococcus pneumoniae carbapenem-resistant vancomycin-resistant penicillin-non-susceptible Pseudomonas aeruginosa Helicobacter pylori Haemophilus influenzae carbapenem-resistant clarithromycin-resistant ampicillin-resistant Enterobacteriaceae Salmonella species Shigella species carbapenem-resistant fluoroquinolone-resistant fluoroquinolone-resistant Staphylococcus aureus vancomycin or methicillin -resistant Campylobacter species fluoroquinolone-resistant Neisseria gonorrhoae 3rd gen. cephalosporin-resistant
    [Show full text]
  • Avoidance of Mechanisms of Innate Immune Response by Neisseria Gonorrhoeae
    ADVANCEMENTS OF MICROBIOLOGY – POSTĘPY MIKROBIOLOGII 2019, 58, 4, 367–373 DOI: 10.21307/PM–2019.58.4.367 AVOIDANCE OF MECHANISMS OF INNATE IMMUNE RESPONSE BY NEISSERIA GONORRHOEAE Jagoda Płaczkiewicz* Department of Virology, Institute of Microbiology, Faculty of Biology, University of Warsaw Submitted in July, accepted in October 2019 Abstract: Neisseria gonorrhoeae (gonococcus) is a Gram-negative bacteria and an etiological agent of the sexually transmitted disease – gonorrhea. N. gonorrhoeae possesses many mechanism to evade the innate immune response of the human host. Most are related to serum resistance and avoidance of complement killing. However the clinical symptoms of gonorrhea are correlated with a significant pres- ence of neutrophils, whose response is also insufficient and modulated by gonococci. 1. Introduction. 2. Adherence ability. 3. Serum resistance and complement system. 4. Neutrophils. 4.1. Phagocytosis. 4.1.1. Oxygen- dependent intracellular killing. 4.1.2. Oxygen-independent intracellular killing. 4.2. Neutrophil extracellular traps. 4.3. Degranulation. 4.4. Apoptosis. 5. Summary UNIKANIE MECHANIZMÓW WRODZONEJ ODPOWIEDZI IMMUNOLOGICZNEJ PRZEZ NEISSERIA GONORRHOEAE Streszczenie: Neisseria gonorrhoeae (gonokok) to Gram-ujemna dwoinka będąca czynnikiem etiologicznym choroby przenoszonej drogą płciową – rzeżączki. N. gonorrhoeae posiada liczne mechanizmy umożliwiające jej unikanie wrodzonej odpowiedzi immunologicznej gospodarza. Większość z nich związana jest ze zdolnością gonokoków do manipulowania układem dopełniacza gospodarza oraz odpor- nością tej bakterii na surowicę. Jednakże symptomy infekcji N. gonorrhoeae wynikają między innymi z obecności licznych neutrofili, których aktywność jest modulowana przez gonokoki. 1. Wprowadzenie. 2. Zdolność adherencji. 3. Surowica i układ dopełniacza. 4. Neutrofile. 4.1. Fagocytoza. 4.1.1. Wewnątrzkomórkowe zabijanie zależne od tlenu. 4.1.2.
    [Show full text]