and its Sections Tribune • Cell Transplant Society • International Pancreas and Islet Transplant Association • International Society for Organ Donation & Procurement • International Xenotransplantation Association • Intestinal Transplant Association • Transplant Infectious Disease

d e c e m b e r 2006 Volume III Issue III o f f i c i a l n e w s l e t t e r o f t h e transplantation s o c i e t y

Present and future Key Opinion Leaders meet in Barcelona and Buenos Aires

n intimate gathering of 46 transplantation leaders met in Barcelona for the inaugural New Key AOpinion Leader meeting in September to discuss present and future transplantation challenges.

“We have kept the format small and infor- by TTS with the assistance of Drs Josep mal in order to encourage in-depth discussion Lloveras and Josep Grinyo, from the Catalan of the issues presented,” explained Kathryn Transplantation Society, on program develop- Wood, outgoing-TTS President. “We invited ment and meeting logistics. established TTS member investigators from A second New Key Opinion Leader meet- each of the global regions to attend the meet- ing was held at the Sheraton ing with one of their research fellows or junior Buenos Aires, Argentina at the (above) Delegates faculty whom they think have the potential to end of October and was orga- met in Barcelona for the first New be one of the leaders in the field of transplan- nized with the assistance of Key Opinion Leader tation in the future. It was a great experience Drs Domingo Casadei and Felix meeting. (left) Felix to meet such successful young investigators,” Cantarovich. Topics covered Cantarovich, Kathryn she continued. included the impact of innate Wood and Domingo Discussions focused on whether or not reg- immunity and inflammation Casadei. (below) ulatory T-cells are critical for graft acceptance, on graft outcome, the impact Josep Lloveras, factors influencing long-term renal allograft of transplant infectious dis- Kathryn Wood and outcomes, non-heart beating donors, cardio- ease on long-term outcomes, Josep Grinyo. vascular diseases in , tumors and transplantation, medical and ethi- translational studies exploring novel strategies, cal aspects in transplantation, ABO incompat- and factors influencing long-term liver trans- ible donor recipient pairs, and using dendritic plantation outcomes. cells to stimulate and manipulate the immune Participants thought it was well organized, response to a transplant. interesting, a valuable learning experience, TTS would like to thank Wyeth and a true success. “It is a great format for Pharmaceuticals for supporting the meetings cross-disciplinary interactions and for intro- in Barcelona and Buenos Aires through an ducing young investigators,” said one partici- unrestricted educational grant. pant following the meeting. A third meeting will take place in January The meeting, held at Hostal de La Gavina, 2007 in Hong Kong. S’Agaro, Barcelona, Spain, was organized

Four decades of International Cooperation, Innovation, Growth and Progress

New TTS International Over 6000 delegates Medawar Prize: TTS In this Headquarters in at 1st World honours three Montreal Transplant outstanding issue Congress members …2 …3 …7 Nicholas Tilney

I n t e r vi e w w i th the pres i d e n t

icholas Tilney has a clear vision of the first guidelines for practice for the Society. where the Society should be headed in In 1990 he was elected Vice-President, and then Nan age when transplantation ethics are named President-elect in 2004. challenged on a daily basis around the globe “It’s wonderful and very flattering to and is excited about making his vision reality. have been elected to this position. I am a bit “I want to thank Kathryn Wood and overwhelmed with the breadth of activities Jeremy Chapman for the tremendous initia- within the Society, but I am excited too. It is a tives they put in motion. I hope to be able demanding position that I am ready to take on to carry-on what they have started in terms as a challenge,” noted Tilney. of positioning TTS on the international stage With the increasing complexity of the through the Society’s important relationship Society and because of its many new initia- with the World Health Organization (WHO).” tives, TTS has opened a new International “All of us in the field are worried about Headquarters in Montreal. “The Society is the irregularities in transplantation in China, about much more than giving conferences India, the Middle East, Eastern Europe, and now. It’s becoming an international force for the Philippines, to name a few. I believe it the whole field of transplantation. It is an is the Society’s responsibility to publicize operation that requires dedication by many the irregularities and unethical behaviors in people,” explained Tilney. Nicholas Tilney transplantation, not only on our own but in Originally from New Jersey, Tilney, the collaboration with the WHO, which has the Francis D. Moore Professor of at power to stimulate governments around the Harvard Medical School and a Senior Surgeon world into action,” said Tilney. at the Brigham and Women’s Hospital in Tribune is published three times per year by The Transplantation Other goals over the next two years include Boston, was educated at Cornell University Society (TTS). Views expressed in increasing membership among younger Medical College in New York. He received news and feature articles are those members of the global transplant commu- his surgical training at Peter Bent Brigham of the individual quoted. nity, enhancing activity of TTS’ Sections, and Hospital and was trained in transplanta- expanding the educational thrust of the Society tion biology at Oxford University and the TTS gratefully acknowledges the Corporate Partners whose gener- through communication and technology. University of Glasgow. Prior to his retirement, ous support makes the work of the Latin America, Singapore, and other areas Tilney headed the kidney transplant unit for Society possible: of Asia have a growing amount of transplant many years at Brigham and Women’s Hospital Astellas Pharma Inc. activity and have been traditionally isolated directed the Surgical Research Laboratory at F. Hoffmann-La Roche Ltd. from the majority of TTS activities. As a Harvard Medical School. He edited the text Genzyme Corporation result, the Society hopes to be able to reach Transplantation Biology, and is the author of a Novartis Pharma AG practitioners in these regions through the Key history of the field, Transplant: from Myth to Wyeth Pharmaceuticals Opinion Leader meetings. Including council Reality.  Editor in Chief members from diverse regions around the Henrik Ekberg world is another TTS initiative. Greetings from the President Contributors Tilney’s history with TTS dates back to 1973 Jeremy Chapman when he first became a member. He was elect- On behalf of The Transplantation Society, Annika Tibell Nicholas L. Tilney ed to the Council in 1984 and acted in a variety we hope you have a happy, of capacities over his 6-year tenure, including Laurence Turka d Kathryn Wood/Monica Dolton chairing the Ethics Committee that published safe, and festive Holiday Season. International Headquarters Filomena Picciano, Director of Society Operations Frank Lindo Verissimo, TTS on the move Membership Services Manager he Transplantation Society recently announced the Editorial, production, publication management appointment of Filomena Picciano to the position of Southlea Communications Inc. TDirector of Society Operations. in partnership with Robin Palin Fil has four years experience with TTS, has worked in con- Public Relations Inc. ference management and has many years of experience in the For more information: travel industry. We welcome her to this newly created role in The Transplantation Society the Society management. Frank Lindo Verissimo will join her International Headquarters as Membership Services Manager. 1255 University Street, Suite 325 Montreal, QC H3B 3B4 Please note the Society’s new address and come to see E-mail: info@transplantation-soc. the new International Headquarters if you are visiting the org Montreal area.  Telephone: +1-514-874-1717 Filomena Picciano, Director of Fax: +1-514-874-1716 Society Operations www.transplantation-soc.org  Inaugural World In Transplant BRIEF Congress a success ver six thousand delegates from The Transplantation Society (TTS), Expect e-posters at Othe American Society of Transplant the XXII TTS Congress Surgeons (ASTS), and the American Transplant Society (ATS) gathered in Boston, Francis Delmonico and Sir Peter Morris meet in Sydney Massachusetts in July to hear global leaders at the TTS booth. Morris wears an Australian You can expect a great program present cutting-edge research affecting the bush hat in honour of TTS’ 2008 Congress in at Sydney 2008, with cohesive, Sydney, Australia. field of transplantation. concurrent, and improved For TTS it was a 40th Anniversary celebra- poster sessions. tion and a welcoming ceremony for the new What’s Hot (Basic Science) Building on the success of Officers and Councillors. TTS installed a new Laurence Turka’s What’s Hot (Basic Science) the World Transplant Congress, President, Nicholas Tilney, and a new slate lecture, a World Transplant Congress (WTC) the Sydney Congress com- of Councillors representing each global region highlight, reviewed recent research in trans- (See page 8 for a full list). plantation and immunology. mittee is working on the idea TTS’ much anticipated prizes were dis- Evidence from several laboratories of electronic posters to avoid tributed during the Presidential address described a subset of IL-17 producing T-cells transporting large cardboard and at the President’s cocktail party. These (Th17) that are distinct from Th1 and Th2 posters. Poster sessions need to were the distinguished Medawar Prize, the cells. They are found at sites of tissue injury be improved in order to allow TTS Recognition Awards, the TTS Research in auto-immune diseases. Antibodies to IL-17 for effective interaction among Fellowships, and the Young Investigator block the incidence and severity of experimen- investigators carrying out stud- Awards (See pages 4 and 5 for more details). tal allergic encephalitis in mice. While TGF-β ies in similar fields. The state-of-the-art program discussed promotes the induction of regulatory T cells If you have any ideas about important new discoveries and initiatives in (Treg), pathogenic Th17 cells are generated improving this process or all areas of transplantation: infectious disease; from naïve T-cells by TGF-β plus IL-6. Thus, thoughts on how to introduce ethics and economics; stem cell research; IL-6 is a molecular switch in the generation of virology; islet transplants; global organ allo- pathogenic or regulatory T-cells. e-posters please contact cation; pediatrics; bioartificial organs and Treg are important in maintaining immune Jeremy.Chapman@ devices; gene therapy; living kidney donation; tolerance and Turka focused on the roles of transplantation-soc.org. cardiovascular disease after renal transplants; IL-2 and IFN-γ. Patients with chemotherapy- skin cancer in solid organ transplants; immu- induced lymphopenia were treated with IL-2 Ensure the publication nosuppression minimization and withdrawal; which markedly increased their Treg cells. of your clinical trials T-cells and B-cells; and reproductive issues. The IL-2 induced Treg cells were similar to Senator Hillary Clinton, who has actively those in normal hosts. Neutralizing IFN-γ dur- The American Journal of lobbied for increased funding for stem-cell ing transfer of alloantigen reactive Treg cells Transplantation recently pub- research, addressed the World Transplant resulted in skin graft loss in mice. The func- lished a special article calling Congress attendees. The other presenter was tion and generation of Treg cells was impaired for a uniform clinical trial reg- Alonzo Mourning, NBA champion and a kid- in IFN-γ deficient mice, indicating a role for istration policy for Journals of ney transplant recipient. IFN-γ in the activation of Treg cells during tol- Kidney Disease, Dialysis and erance development Transplantation. Toll-like receptors (TLRs) were discussed To have results of a clini- by Turka. Hyaluronan is an extracellular com- cal trial published in any of ponent which is released after tissue injury and stimulates TLR2 and TLR4. Hyaluronan- the major journals in the field TLR interactions provide signals initially of transplantation, the study inducing inflammatory reactions and later pro- will need to be available to the tecting epithelial cells and promoting recovery. general public through a trial Immune complexes with mammalian nucleic registry. The registry must meet acids activate TLRs and may be involved in a specific list of requirements, systemic lupus erythematosis. which include elements such as Turka also discussed anatomy of the the trial’s investigators, research immune response, dendritic cells and systems questions, methodology, inter- modelling, a technique for handling large and TTS’ 40th Anniversary was marked by a VIP ventions, outcomes measured, celebration at the World Transplant Congress complex sets of data. in Boston where past TTS Presidents For more information about WTC’s pro- participated in a ceremonial cake cutting. gram, please visit www.wtc2006.org  Continued on page 7

 Awards: Recognizing the best and brightest stars in transplantation

The Medawar Prize was named after Society co-founder Sir Peter Medawar. It is recognized as the highest dedicated award for outstanding contributions in the field of transplantation. The Medawar Prize has been awarded to two or The Medawar Prize more recipients at each of TTS’ biennial Congresses since 1990. The award is made possible by a generous endowment from Novartis Pharma AG.

Carl G. Groth entific and medical/surgical accomplishments have been rewarded by many knighthoods and Carl Groth’s vast professional experience is honors from his country, other nations and his punctuated with success. He became Chief Church. He has also been Vice-President and of Transplantation at Huddinge Hospital, President of TTS. Stockholm, Sweden, in 1976 and Professor In his private life, Häyry has engaged in of Transplantation Surgery at the Karolinska hands-on initiatives in ecology, in preservation Institute in 1984. He was involved in the first of Byzantium culture and art, and in charitable human . He did early work enterprises to improve healthcare in impover- in human pancreas transplantation, especially ished nations. the surgical techniques and the effects on the secondary complications of diabetes. He pio- neered work to find a cure for metabolic diseas- es by organ or cellular transplantation. A unique Sir Peter Morris study in the early 1990s transplanted fetal pig Professor Sir Peter Morris is Nuffield Professor islets into diabetic patients and resulted in evi- of Surgery Emeritus, and former Chairman of Carl G. Groth dence of survival of the pig tissue. He initiated, the Department of Surgery, and Director of the and led, the multicenter study which showed Transplant Centre, University of Oxford. He is that Sirolimus can be used as a baseline immu- past President of the Royal College of Surgeons nosuppressive agent. of England, former Chairman of the British Groth was the President of The Heart Foundation, Chairman of the Council of Transplantation Society (2000-2002). He is the Institute of Health Sciences at the University an Honorary Fellow of the Royal College of of Oxford, a Fellow of the Royal Society and Surgeons of England, the American Surgical a Foreign Member of the Institute of Medicine Association and the American Society of of the National Academy of Sciences and the Transplant Surgeons. He was a member of the American Philosophical Society. Nobel Assembly at Karolinska Institute 1986- His scientific career has revolved around 1999 and Chairman in 1998. He was awarded transplantation and transplantation biology, with the King’s Medal for “Eminent accomplishments a major interest in the immune response to his- in transplantation.” He is currently on the newly tocompatibility antigens and its suppression. His appointed WHO Expert Advisory Panel on clinical interests have been in transplantation Human Cell, Tissue and Organ Transplantation. and vascular surgery. Pekka Häyry He is a former President of TTS, the British Transplantation Society, the European Surgical Pekka Häyry Association and the International Surgical Society. He received several prizes for his work, Pekka Häyry was born in 1939 in rural Finland the most prestigious is the Lister Medal. He is where his mother had been evacuated dur- the editor of : Principles ing the Russian siege of Helsinki; his father and Practice, which is now in its 5th edition, remained at the front with the Finnish Army. He and the widely acclaimed Oxford Textbook of returned to Helsinki after the war and received Surgery. his M.D. and Ph.D. degrees. His research pro- In 1996 he was knighted for services duced a cluster of articles that became instant to medicine. He has been a principle edi- classics of transplantation immunology. He tor of Transplantation and currently serves became an accomplished surgeon climbing as European Special Features Editor of the ranks to Associate Chief of Surgery at the Transplantation. Helsinki University Hospital. He was named Professor Extraordinarius of Transplantation Surgery and Immunology at the University of Sir Peter Morris Helsinki. Since 1981, he has been Physician in Chief and Director of Transplantation Immunology of the University Hospital. His sci-

 Awards: Recognizing the best and brightest stars in transplantation

TTS Research Fellowships TTS Recognition Awards TTS Research Fellowships are The 2006 TTS Recognition Awards were presented at the World awarded for a period of two Transplant Congress in July to investigators who have made years to support basic and outstanding contributions in transplantation. The 2006 winners are: clinical research in the field of TTS-Roche Award for Outstanding Achievement transplantation in the laboratory or clinical unit. The Fellowships Transplantation Science (Basic) Lucienne Chatenoud are designed to provide research TTS-Roche Award for Excellence in Translational Science training for new young investigators Christian Larsen and Thomas Pearson with the potential of making significant contributions to the field TTS-Roche Award for Outstanding Achievement of transplantation. Transplantation Science (Clinical) Camillo Ricordi The 2006 winners are: TTS Research Fellowship TTS-Roche Award for Worldwide Impact in Transplantation Xian-Lian Li Wojciech Rowinski TTS-Basic Science TTS-Roche Award for Excellence in Transplant Infectious Research Fellowship Disease Robert Rubin Joyce Popoola TTS-Genzyme Award for Innovation in Surgery TTS-Transplantation and Technology Proceedings/Transplantation Jean-Michel Dubernard Research Fellowship TTS-Genzyme Award for Giorgio Raimondi Education and Training in Recipients of the 2006 TTS Research TTS-Roche Research Transplantation Fellowship (left to right) Xian-Lian Li, Peter Neuhaus Fellowship in Transplant Joyce Popoola, Josep Oriol Manuel Infectious Disease Altes, Giorgio Raimondi. Josep Oriol Manuel Altes TTS Recognition Award recipients (right to left) Peter Neuhaus, Jean-Michel Dubernard, Camillo Ricordi, Thomas Pearson, Christian Young Investigator Awards Larsen, Lucienne Chatenoud. Missing from photo: Robert Rubin, and Wojciech Rowinski. 2 0 0 6 r e c i p i e n t s

Recipients of the TTS-Astellas Pharma Inc. Young Investigator Award in 2006 submitted abstracts to the 1st World Transplant Congress in Boston and received the highest scores by an international review panel. Recipients of the award are listed on the TTS website and will be featured in Tribune throughout 2007.

S hin I takura J os É C aballero - Chimerism and C orbal á n Islet Allograft Tolerance Pancreas Transportation and Shin Itakura received an award for a study that concluded “Mesenchymal Stem Cells Preservation in Islet Isolation Facilitate Induction of Mixed Chimerism José Caballero-Corbalán studied the effi- and Islet Allograft Tolerance without GVHD cacy of preserving pancreases prior to in Rats.” An intraportal infusion of islets islet isolation either in the Two Layer and bone marrow cells (BMC) with or Method (TLM, n=107) or in University of without mesenchymal stem cells (MSC) was given to diabetic rats. Wisconsin solution (UW) (n=107) alone. More rats (3/6) given MSC developed mixed chimerism and donor The islet equivalent number (IEQ), the IEQ/gram of pancreas specific tolerance than controls (1/6), but the reversal of diabetes and the number of pancreases used for islet transplantation was transient. Short-term immunosuppression post transplant were recorded. Various factors that influence the outcome of achieved chimerism and long-term reversal of diabetes in rats islet isolation, including cold ischemia time, donor BMI, gen- (5/7) given islets, BMC and MSC. Accumulation of CD3/NKR-P1A/ der, age, blood group and cytomegalovirus (CMV) status, were CD8 triple positive NKT cells caused islet cell destruction and was analyzed to check for homogeneity between the groups. He con- blocked by immunosuppression. Rats were protected from GVHD cluded there was “No Beneficial Effect of the Two Layer Method by MSC. (PFC-UW) Compared with Transportation in UW Alone on the Itakura is currently a visiting scientist at California’s City of Outcome of Human Islet Isolation and Clinical Transplantation.” Hope/Beckman Research Institute as part of his Ph.D. studies Caballero-Corbalán is currently a Ph.D. student in the Division at Graduate School of Agricultural and Life Sciences (Tokyo of Clinical Immunology, Transplantation Immunology group University). (Prof. Olle Korsgren) at Uppsala University (Sweden).

 Society takes stand on the use of organs from executed prisoners

t the World Transplant Congress (WTC) in Boston, The Transplantation Society (TTS) Ethics ACommittee officially announced their position against transplanting organs from executed prisoners.

“The Society and its Ethics Committee have been working towards establishing global ethical transplantation practices over the past few years and has repeat- edly declared its opposition to the use of organs from executed prisoners. TTS has a responsibility to provide global leadership on ethical practices and the situation in China necessitated TTS com- ment,” said Annika Tibell, TTS’ newly “Although appointed Ethics Committee Chair. we commend TTS’ statement emphasizes a fun- damental principle that organs and tis- the Chinese sues are given freely, without coercion. Prisoners that are executed have virtually government’s recent become the only source of transplantable organs in China, with more than 11,000 efforts to improve transplants performed in 2005. Lucrative and unethical transplant tourism has TTS Ethics Chair Annika Tibell regulation on this become an international concern with no oversight of recipient candidacy or issue, recovering recipient outcome. deceased donation issue. The Committee organs from “Chinese transplant centers have been will also discuss transplant tourism, known to advertise on the web offer- commercialization, protection of live executed prisoners ing transplantations to foreign citizens. donors, reimbursement to live donors Although we commend the Chinese gov- and donation after cardiac death,” con- is not an ernment’s recent efforts to improve regu- tinued Tibell. lation on this issue, recovering organs Tibell has been a member of TTS acceptable practice.” from executed prisoners is not an accept- since the early 1990s and a member able practice. Hopefully international of the Ethics Committee since 2004. media attention and our lobbying efforts, She has been active in the European in conjunction with the World Health Association for the Study of Diabetes Organization (WHO), will help bring an (EASD) as President for the working end to these unethical procedures,” said group on Artificial Insulin Delivery, Islet Tibell. and Pancreas Transplantation and has Going forward, the Committee’s 14 been the Vice President of the European members from Sweden, USA, Canada, Council Xenotransplantation Committee. Pakistan, India, Lebanon, Mexico, Brazil, She studied medicine at The Karolinska Singapore, Japan and Poland will ana- Institute and joined the Department of lyze ethical issues in the field of trans- Transplantation Surgery in Stockholm in plantation during their two-year term. 1987. She is now the Chairman of the “Recommendations developed at the Department and Head of the Research Amsterdam and Vancouver Forums on Committee at the Karolinska University live donation will be our guidelines for Hospital. developing standards of practice on the  v TTS Sections In n e w s & u p d at e S BRIEF IXA discusses transplant ethics Xenotransplantation leader dies in Boston IXA notes with great sadness the passing of a Continued from page 3 Kazu Yamada, Emanuele Cozzi and Megan valued member and colleague, Robert Zhong, timelines, number of targets, Sykes, together with various contributors suc- University of Western Ontario, who died of funding source and status. ceeded in highlighting and critically evaluating lung cancer on September 8th. Dr. Zhong will For a list of registries that the status of xenotransplantation at WTC 2006 be greatly missed for his research productiv- currently meet the prescribed during several industry specific meetings. ity and enthusiasm for our field, and for his criteria or for more information IXA hosted three meetings in Boston, warm and collegial personality. please refer to the American including a Satellite Symposium entitled Journal of Transplantation Advances in xenotransplantation: is the Gal TTS Sections plan first 2005; 5:643. knockout pig essential to clinical success? joint meeting and a symposium about Xenotransplantation: CTS, IPITA and IXA invite you to the first Current standards for clinical trials. The Joint Meeting of the Cell Transplant Society proceedings from these meetings will (CTS), The International Pancreas and Islet be published in an upcoming issue of Transplant Association (IPITA), and the Xenotransplantation. International Xenotransplantation Association The Global Alliance These timely meetings provided an update (IXA). It will be held in Minneapolis, MN, on ethical, regulatory and safety standards for USA from September 15-20, 2007. The con- for Transplantation clinical xenotransplantation and highlighted ference Chairs will be David Sutherland, Representatives from the 15 some of the important issues related to xeno- Bernhard Hering, and Megan Sykes. Visit member societies on the Global transplantation in emerging nations. The sym- www.cts-ipita-ixa-2007.org for further details. Alliance for Transplantation posium served as a backdrop for a closed ses- Board met in Boston during sion the following day on the Mexico City por- Global leaders in intestinal the WTC to establish four areas cine islet/Sertoli cell transplants. The meeting included IXA’s Council, Ethics Committee, transplantation to discuss where they will take action: and Dr. Rafael Valdes and his collaborators 20 years of evolution relationships, information, edu- and was held in response to a request by Dr. Under the University of California, Los cation, and guidelines. Valdes. It permitted a detailed and candid dis- Angeles (UCLA) patronage, with Dr. Douglas With communication and cussion between all parties of the regulation, Farmer, MD as Symposium Chair and information identified as major source animals, ethics, and data surrounding Director, the X International Small Bowel priorities, an international this work. Transplantation Symposium is scheduled to dictionary for use by registries take place in Los Angeles, California from will be developed in 2007 with WHO and IXA collaborate September 5-8, 2007. input from global partners. This The University Hospital Geneva and the Lectures, plenary sessions, workshops, dictionary is also designed to and posters will focus on new techniques and International Xenotransplantation Association support small registries and management of intestinal failure, analysis of (IXA) have created a website www.humanx- augment statistical techniques. enotransplant.org in collaboration with the UNOS waiting list for intestinal transplant, WHO will introduce the Global World Health Organization (WHO). new surgical techniques, immunosuppression Knowledge in Transplantation The site aims to establish an inventory on and weaning protocols, post-transplant infec- all types of current human xenotransplantation tions and malignancy complications, intestinal website as well: www. practices. While it is known that xenotrans- graft monitoring tests and much more. who.int/transplantation/ plantation is performed in several countries Registration for the Symposium opened knowledgebase/en. with or without national oversight or regula- October 15, 2006. Abstract submission Guidelines for living donor tion, the scope of these practices is unknown. deadline is scheduled for April 2007. More for both renal and non-renal The decision to launch the site came from information can be obtained at the website transplants are being established consultations between WHO and experts in http://transplant.mednet.ucla.edu/isbts2007/. in a TTS and National Kidney Visit this site to join the mailing list to receive the field of xenotransplantation last year. Foundation collaborative effort. further information. The collection of worldwide data on human A report is due to be published xenotransplantation is being led by Leo Bühler in Transplantation soon and at the University of Geneva. The information Basic Science – Mark your calendar work on formal evidence-based will ultimately be used to inform national The 2007 Basic Science Symposium of guidelines is commencing under health authorities, health care staff and the The Transplantation Society will be held public. Its objective is to encourage good prac- September 5-8, 2007 in Halifax, Nova Scotia, the banner of Kidney Disease: tices with internationally harmonized guide- Canada at the Westin Nova Scotian Hotel Improving Global Outcomes lines and regulation of xenotransplantation. and Conference Centre. The event will be (KDIGO). The research group encourages any person co-sponsored by the Canadian Society of The Board has agreed to aware of current human xenotransplantation Transplantation. Visit www.bss2007.ca for meet regularly to keep channels practices to contribute this information at further details.  of communication open and to www.humanxenotransplant.org. foster strong relationships.

 website update u pcomi n g m e e t i n g s Visit our website at www.transplantation-soc.org New Key Opinion Leader Meeting recap Learn what the leaders are talk- Basic Science 2007 Organ Donation ing about by viewing some of Symposium 2007 Congress (9th ISODP the highlights of the New Key Halifax, Nova Scotia, and 6th ITCS) Opinion Leader Meetings held in Barcelona in September and Canada Philadelphia, PA, USA in Buenos Aires in October. September 5 to 8, 2007 November 11 to 14, 2007 Pictures and discussion topics (Westin Nova Scotian Hotel and (Loews Philadelphia Hotel) are now available on the TTS Conference Center) chair: Howard M. Nathan website. chairs: Ken West, Anthony Jevnikar, website: www.isodp2007.org Have you missed an and Lori West issue of Transplantation? website: www.bss2007.ca With paid-up TTS dues you Xth International Small Bowel can access past issues of Transplantation. The journal is Transplantation Symposium available on-line to TTS members Santa Monica, CA, USA 22nd International Congress whose membership dues are Summer 5 to 8, 2007 of The Transplantation Society up-to-date. To read the journal, (Fairmont-Miramar Hotel) visit the TTS website and login Sydney, Australia chair: Douglas G. Farmer to your personal profile. Once August 10 to 14, 2008 you enter your username and website: http://transplant.mednet.ucla.edu/ password, click on the link for isbts2007 chair: Jeremy Chapman “Transplantation Online Access”. website: www.transplantation2008.org This will bring you to the journal Joint Meeting of IXA, IPITA, Publisher’s website where you and Cell Transplant Societies can view Transplantation dating Minneapolis, MN, USA For a list of all meetings back to 1996. September 15 to 20, 2007 please check Fast and easy chairs: Megan Sykes, David Sutherland, www.transplantation-soc.org dues payment Bernhard Hering Become a member of our TTS website: www.cts-ipita-ixa-2007.org family or any of the prestigious Sections and take advantage of all the benefits we have to offer. We offer savings on journals T h e T r a n s p l a n tat i o n S o c i e t y O f f i c e rs and industry meetings to all T h e n e w O ffi c e rs a n d C o u n c i l l o rs of The Transplantation Society were announced TTS and Section members and in July at the World Transplant Congress. To consolidate its position as the leading global organi- much more. Take advantage of zation, the Council will now have representation from all six regions of the world: North America, this easy way to pay your 2007 Latin America, Europe, Africa-Middle East, Oceania, and Asia. Society dues directly online from our website. Officers Hans Sollinger Camillo Ricordi Online Education Nicholas L. Tilney Secretary (North America) New tutorials and video lec- President Francis L. Delmonico Oscar Salvatierra, Jr. (North America) tures by international experts Kathryn Wood Director of Medical Affairs Immediate Past President Manikkam Suthanthiran in all aspects of basic biology COUNCILLORS (North America) and clinical practice are added Jeremy Chapman Maggie Dallman (Europe) Koichi Tanaka (Asia) each month for TTS members President-Elect Henrik Ekberg (Europe) Yves Vanrenterghem to view. Visit the TTS website Megan Sykes John Fung (North America) (Europe) periodically to get up to date Vice President Mehmet A. Haberal Federico Villamil information on the education Richard D.M. Allen (Middle East & Africa) (Latin America) program designed for residents, Senior Treasurer Barry D. Kahan International Headquarters fellows, transplant specialists Ron Shapiro (North America) Filomena Picciano, Director Stephen Lynch (Oceania) and related professionals. Junior Treasurer of Society Operations