Fertility2017
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The AssociationACE of Clinical Embryologists Fertility 2017 Fertility2017 5-7 JANUARY 2017 Edinburgh International Conference handbookConference Conference Centre (EICC) #fertility2017 CONFERENCE HANDBOOK Affiliated Organisations: Supported by: Fertility2017 The AssociationACE of Clinical Embryologists VENUE PLAN VENUE PLAN Level 3 VENUE PLAN PENTLAND PROGRAMME SIDLAW FINTRY PROGRAMME INFORMATION CONFERENCE CONFERENCE INFORMATION AND BIOGRAPHIES SPEAKER ABSTRACTS PREVIEW LOMOND FOYER SOUTRA Level 0 ABSTRACTS Moorfoot AND BIOGRAPHIES Kilsy PRESENTATIONS Tinto LOMOND SUITE th POSTER L L A H Business E N Centre A L B H T A POSTER R REGISTRATION T S O T PRESENTATIONS S K N I L STRATHBLANE HALL ATRIUM EXHIBITOR LIST LIST EXHIBITOR MAIN ENTRANCE EXHIBITION PLAN PLAN Level -2 EXHIBITION INFORMATION EXHIBITOR CROMDALE HALL LENNOX SUITE EXHIBITOR INFORMATION EXHIBITION, POSTERS AND CATERING SPEAKER INDEX Bar INDEX SPEAKER Moffat 12 Lammermuir 2 #fertility2017 Fertility2017 The AssociationACE of Clinical Embryologists CHAIR’S WELCOME VENUE PLAN A warm welcome to Edinburgh and to the International Conference Centre for Fertility 2017. This is the tenth joint Fertility meeting organised by the Association of Clinical Embryologists (ACE), the British Fertility Society (BFS) and the Society for Reproduction and Fertility (SRF). As always, we have attempted to organise an VENUE PLAN exciting scientific programme which appeals to scientists, clinicians, embryologists, nurses and counsellors. I hope you agree there is something for everyone. PROGRAMME The theme for Fertility 2017 is the Ovary with plenary sessions on Developmental and environmental impacts on the ovary, Oocytes, and Ovarian function/dysfunction. There will also be 3 eponymous lectures: The Anne McLaren Memorial Lecture, the Howard Jacobs Lecture and the Bob Edwards Memorial Lecture. These, together with the Update sessions, will allow renowned experts to present their latest data in a wide range of topics of interest to delegates. PROGRAMME Fertility 2017 is set to be the most successful yet, having an unprecedented number of abstract submissions and delegates registered. Consequently, competition to present in the parallel, short oral communication sessions was immense. We are INFORMATION CONFERENCE also in the fortunate position to have a large number of high quality abstracts being presented during the poster sessions. The social events are an integral part of Fertility 2017 providing delegates with an excellent opportunity to network and discuss science. This year we are taking a break from the usual football tournament and instead have organised ten pin bowling followed by a meal. The venue for dinner on Thursday evening is the Caves where you will experience the historic CONFERENCE 18th Century South Bridge Vaults. Finally, on Friday the conference dinner will be held at the Conference Centre and followed INFORMATION by a traditional Ceilidh band. AND BIOGRAPHIES Organising Fertility 2017 has very much been a team effort and I would particularly like to thank members of the joint ABSTRACTS Programme Committee who have worked diligently to prepare what I hope you will agree is an outstanding scientific programme. I would also like to thank the Conference organisers, Profile Productions and the many sponsors and exhibitors. It is a pleasure to welcome you to the Fertility 2017 conference and the beautiful city of Edinburgh. I hope you find the meeting both enjoyable and scientifically rewarding. ABSTRACTS AND BIOGRAPHIES Dr Franchesca Houghton PRESENTATIONS Fertility 2017 and SRF Programme Committee Chair POSTER University of Southampton POSTER Conference organisers: PRESENTATIONS ACKNOWLEDGEMENTS Profile Productions Ltd EXHIBITOR Profile Productions Ltd, Boston House, LIST Association of Clinical 69-75 Boston Manor Road, Brentford, Middlesex, TW8 9JJ Embryologists LIST The AssociationAC of Clinical EmbryologistEs c/o Profile Productions Ltd, Tel: +44(0)20 3725 5840 EXHIBITOR Boston House, 69-75 Boston Manor Fax: +44(0)84 4507 0578 Road, Brentford, Middlesex, TW8 9JJ Email: [email protected] Tel: +44(0)20 3725 5840 Website: www.profileproductions.co.uk EXHIBITION Fax: +44(0)84 4507 0578 PLAN Email: [email protected] Website: www.embryologists.org.uk CONTENTS PLAN British Fertility Society EXHIBITION Conference programme 4-11 c/o Profile Productions Ltd, Boston House, 69-75 Boston Manor Conference information 13 INFORMATION EXHIBITOR Road, Brentford, Middlesex, TW8 9JJ Speaker abstracts and biographies Tel: +44(0)20 3725 5849 Fax: +44(0)84 4507 0578 - Plenary speakers 14-19 Email: [email protected] 21-33 - Update sessions EXHIBITOR Website: www.britishfertilitysociety.org.uk INFORMATION - Short papers 36-68 Society for Reproduction - Exhibitors symposia 69 SPEAKER and Fertility Poster presentations 70-153 INDEX c/o Conference Collective, 8 Waldegrave Road, Teddington, Exhibitor list 154 INDEX Middlesex, TW11 8GT Exhibition plan 155 SPEAKER Tel: +44(0)20 8977 7997 Exhibitor information 156-162 Email: [email protected] Website: www.srf-reproduction.org Speaker index 163 3 #fertility2017 Fertility2017 The AssociationACE of Clinical Embryologists CONFERENCE PROGRAMME VENUE PLAN Wednesday 4 January 17.00 Ten pin bowling at Fountain Park VENUE PLAN 19.00 After at Akva! PROGRAMME Thursday 5 January 08.00 Registration, refreshments, exhibition and poster presentations PENTLAND PLENARY SESSION - Developmental and environmental impacts on the ovary PROGRAMME 09.15 Chair’s welcome Dr Franchesca Houghton, Fertility 2017 Programme Chair and Associate Professor in Stem Cells and INFORMATION CONFERENCE Developmental Biology, University of Southampton 09.25 Development of the ovary and rescue after chemotherapy Prof Blanche Capel, Professor of Cell Biology, Duke University Medical Centre, USA 09.55 How the environment affects ovarian function and the oocyte CONFERENCE Dr Roger Sturmey, Senior Lecturer in Reproductive Medicine, Hull York Medical School INFORMATION 10.25 AND BIOGRAPHIES Replenishing the adult ovarian follicular population: Isolation and characterisation of germ line stem cells ABSTRACTS from adult women Prof Evelyn Telfer, Personal Chair in Reproductive Biology, University of Edinburgh 11.05 Exhibition, refreshments and attended poster presentations of odd numbered posters ABSTRACTS 12.00 PENTLAND PLENARY SESSION - The Anne McLaren Memorial Lecture AND BIOGRAPHIES Chair: Dr Tony Michael, Director of Taught Programmes (Biological & Chemical Sciences) and Reader in PRESENTATIONS Reproductive Biology, Chair, Society of Reproduction and Fertility POSTER The role of sister germ cells in oocyte differentiation Dr Allan Spradling, Department of Embryology, Carnegie Institution for Science/ HHMI, Baltimore, USA POSTER 13.00-13.45 SRF AGM FINTRY PRESENTATIONS 13.00 Lunch, exhibition and poster presentations EXHIBITOR LIST 14.15-15.45 Short paper SESSIONS A A1 Emerging strategies in ART FINTRY LIST Chair: Dr James Nicopollous, Consultant Gynaecologist, The Lister Hospital, London and Dr Yacoub Khalaf, EXHIBITOR Guy’s and St Thomas’ Hospital 14.15 Multilocus genetic risk scores for poor ovarian response - Joaquin Llácer, Instituto Bernabeu Biotech, Spain EXHIBITION 14.30 For women undergoing double embryo transfer on day five, the addition of a poor quality embryo may have PLAN a detrimental effect on assisted reproduction outcome - Alison Richardson, University of Nottingham 14.45 A second injection of kisspeptin-54 safely improves oocyte maturation during in vitro fertilisation therapy in women at high risk of ovarian hyperstimulation syndrome - Ali Abbara, Imperial College London PLAN EXHIBITION 15.00 Progesterone assay concentrations to guide whether to proceed to a fresh embryo transfer or to freeze all suitable embryos are insufficiently reliable - Jennifer Lyon, GCRM, Glasgow INFORMATION 15.15 EXHIBITOR The clinical value of time-lapse as an efficacious embryo selection tool: A systematic literature review and meta-analysis of 45 studies involving 28876 embryos - Stephanie Yip, Imperial College London 15.30 Intralipid infusion does not result in improved live birth rates in women with recurrent implantation failure undergoing IVF treatment and is associated with an increased risk of congenital fetal malformations: a EXHIBITOR double blinded randomised controlled trial - Islam Gamaleldin, University of Bristol INFORMATION A2 Sperm integrity and function MOORFOOT SPEAKER Chair: Prof Allan Pacey, Editor, Human Fertility and Prof Chris Barrett, University of Dundee INDEX 14.15 SRF/SRB Exchange paper: Cellular samurais and sperm: Katnal2 is an essential regulator of microtubules in haploid male germ cells and INDEX sertoli cells - Jessica Dunleavy, Monash University, Australia SPEAKER 14.30 Does exposure to cisplatin impair survival and proliferation of spermatogonial stem cells in prepubertal mouse testis? - Frederica Lopes, University of Edinburgh 4 #fertility2017 Fertility2017 The AssociationACE of Clinical Embryologists CONFERENCE PROGRAMME VENUE PLAN 14.45 Effect of electronic-cigarette flavourings on (I) human sperm motility, chromatin integrity in vitro and (II) mice testicular function in vivo - Helen O’Neill, UCL 15.00 - Sheena Lewis, Sperm DNA quality in Hr6b (Ubiquitin-conjugating enzyme) Knockout Mice: DNA damage study VENUE PLAN Queen’s University Belfast 15.15 DNA sequence analysis of the sperm HALO provides evidence for sequence-specific compartmentalisation of - Adel Binhurahem, University of Leeds PROGRAMME chromatin