SINGLE CATEGORY MEDICATION REPORTS Quick Reference List

PAIN MEDICATION CARDIOVASCULAR REPORT MEDICATION REPORT

Opioid Beta NSAIDs Other Statins Other Analgesics Blockers

Celecoxib Codeine Amitriptyline Atorvastatin Metoprolol Acenocoumarol Flurbiprofen Hydrocodone Duloxetine Fluvastatin Clopidogrel Ibuprofen Morphine Nortriptyline Simvastatin Flecainide Meloxicam Oxycodone Irbesartan Piroxicam Tramadol Losartan Propafenone Warfarin

GASTROINTESTINAL MENTAL HEALTH MEDICATION REPORT MEDICATION REPORT

Proton Pump Anti-Emetics Antidepressants Antipsychotics Other Inhibitors Amitriptyline Fluoxetine Paroxetine Aripiprazole Atomoxetine Dexlansoprazole Metoclopramide Citalopram Fluvoxamine Sertraline Brexpiprazole Clobazam Esomeprazole Ondansetron Clomipramine Imipramine Venlafaxine Chlorpromazine Diazepam Lansoprazole Desipramine Mirtazapine Vortioxetine Clozapine Melatonin Omeprazole Doxepin Moclobemide Haloperidol Pantoprazole Duloxetine Nortriptyline Olanzapine Rabeprazole Escitalopram Pimozide Quetiapine Risperidone Zuclopenthixol For all enquiries contact myDNA clinical support on 1844 472 7896 or email [email protected] HEALTH CARE PROFESSIONAL REPORTS Medication List Below is a list of the main medications covered by the myDNA Medication Test (grouped by the gene which primarily impacts the medication response). Note: CYP450 enzymes generally metabolise pharmacologically active drugs into less active metabolite(s). Conversely, prodrugs are pharmacologically inactive, and are converted into active metabolite(s).

CYP2D6 SLCO1B1

Beta Opioid Antidepressants Anti-emetics Antipsychotics Other Statins Blockers Analgesics Atorvastatin Amitriptyline Duloxetine Nortriptyline Metoclopramide Aripiprazole Metoprolol Codeine* Atomoxetine Fluvastatin Clomipramine Fluoxetine Paroxetine Ondansetron Brexpiprazole Hydrocodone Flecainide Simvastatin Desipramine Fluvoxamine Venlafaxine Chlorpromazine Oxycodone Propafenone Doxepin Imipramine Vortioxetine Haloperidol Tramadol* Tamoxifen* Mirtazapine Pimozide Tetrabenazine Risperidone Tolterodine Zuclopenthixol OPRM1 Opioid Analgesics Morphine

CYP1A2 CYP2C19 CYP2C9

Antipsychotics Other Proton Pump NSAIDs Other Antidepressants Other Inhibitors Clozapine Melatonin Celecoxib Acenocoumarol Olanzapine Dexlansoprazole Amitriptyline Clobazam Flurbiprofen Fluvastatin Esomeprazole Citalopram Clopidogrel* Ibuprofen Irbesartan Lansoprazole Clomipramine Diazepam CYP3A5 Meloxicam Losartan* CYP3A4 Omeprazole Doxepin Voriconazole Piroxicam Phenytoin Other Pantoprazole Escitalopram Warfarin Antipsychotics Tacrolimus Rabeprazole Imipramine Moclobemide Quetiapine *This is a prodrug. Sertraline (Metabolised in the body into an active form)