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Trimethoprim 100Mg and 200Mg Tablets

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Trimethoprim 100Mg and 200Mg Tablets Package leaflet: Information for the patient Trimethoprim 100mg and 200mg tablets Read all of this leaflet carefully before you start • Trimethoprim should not be given to premature babies or babies taking this medicine because it contains important during the first few weeks of life. information for you. You should let your doctor know and ask his/her advice if you suffer from • Keep this leaflet. You may need to read it again. or have ever had any of the above. • If you have any further questions, ask your doctor or Trimethoprim can increase potassium blood levels. Patients at risk of pharmacist. increased potassium blood levels include those with kidney problems, • This medicine has been prescribed for you only. Do poorly controlled diabetes, or those on certain medicines or potassium supplements. The symptoms of severe hyperkalaemia might include not pass it on to others. It may harm them, even if muscle cramps, irregular heart rhythm, diarrhoea, nausea, dizziness their signs of illness are the same as yours. or headache. Your doctor may perform blood tests to monitor your • If you get any side effects, talk to your doctor or potassium blood levels. pharmacist. This includes any possible side effects Your doctor may wish to do regular blood tests if you need long-term not listed in this leaflet. See section 4. treatment or are prone to anaemia. Children What is in this leaflet This dosage form is not suitable for use in children younger than 6 years. 1 What Trimethoprim tablets are and what Other medicines and Trimethoprim tablets they are used for Please inform your doctor or pharmacist if you are taking, or have 2 What you need to know before you take recently taken any other medicines, even those not prescribed. Your medicine may interfere with other medicines that you are taking. Trimethoprim tablets Take care with the following medicines: 3 How to take Trimethoprim tablets • repaglinide, used to treat diabetes 4 Possible side effects • procainamide, to treat abnormal heart rhythm • digoxin, to treat certain heart conditions 5 How to store Trimethoprim tablets • potassium supplements 6 Contents of the pack and other information • medicines known as ACE inhibitors and angiotensin II antagonists (used to treat high blood pressure and certain heart conditions). • heparin (used to treat and prevent blood clots) 1 What Trimethoprim tablets are and what they are • diuretics (water tablets such as eplerenone, spironolactone, amiloride or triamterene) used for • rifampicin (antibiotic), used to treat TB Trimethoprim Tablets belong to a group of medicines known as • anticoagulants (to prevent clots from forming in the blood e.g. antibacterials. They are used to kill a wide range of bacteria that cause warfarin) infections in your body, primarily urinary and respiratory tract infections. • phenytoin, to treat epilepsy This medicine can also be used for prevention of recurrent urinary tract • pyrimethamine and dapsone, used to treat malaria infections. • immunosuppressant drugs - used in cancer treatment (e.g. methotrexate) or to treat organ rejection after transplant (e.g. 2 What you need to know before you take azathioprine or ciclosporin) Trimethoprim tablets • bone marrow depressants Do not take Trimethoprim tablets if you: Pregnancy and breast-feeding • are allergic (hypersensitive) to trimethoprim or to any of the other If you are pregnant or breast-feeding, think you may be pregnant or are ingredients (see section 6, Contents of the pack and other information) planning to have a baby, ask your doctor or pharmacist for advice before • are pregnant taking this medicine. Trimethoprim should not be used in pregnancy. • suffer from severe liver problems DO NOT take Trimethoprim Tablets if you are pregnant. If you are • suffer from any blood disorders such as anaemia breast-feeding, ask your doctor or pharmacist for advice before taking Trimethoprim should not be administered to premature babies or this medicine. infants under 4 months of age. Driving and using machines The tablet form is NOT recommended for use in children under 6 years - There is no evidence to suggest that Trimethoprim Tablets affect the the oral liquid form should be used. ability to drive or operate machinery. Warnings and precautions Important information about some of the ingredients of Talk to your doctor or pharmacist before taking Trimethoprim Tablets Trimethoprim Tablets if you: These tablets contain a sugar called lactose. If your doctor has told you • are pregnant that you have an intolerance to some sugars, contact your doctor before • suffer from kidney problems/kidney disease or are having dialysis taking this medicinal product. treatment • have a deficiency (are low) in folic acid (may cause anaemia) 3 How to take Trimethoprim tablets • are at greater risk of high levels of potassium in your blood Always take this medicine exactly as your doctor or pharmacist has told (hyperkalaemia), e.g. the elderly or those on higher doses you. Check with your doctor or pharmacist if you are not sure. • are also taking repaglinide (medicine for treating diabetes) They can be swallowed with a glass of water, but not chewed, at the • suffer from porphyria (a disorder that causes skin sensitivity to light, same time each day. pain attacks and muscle weakness) Continued top of next column Continued over page 148x210 Leaflet Reel Fed Profile (BST) Trimethoprim Tablets 100mg & 200mg x 6, 14, 28 (UK) Trimethoprim 100mg & 200mg Tablets PIL - UK JDE No.: 50981695 approved for print/date Item number: BBBA6990 Colours Non Printing Colours Dimensions: 148x210 (Reel Fed) 1. Black 1. Profile Originator: T. Hull Dimensions: 148x210 Component: Leaflet for Blisters Origination Date: 20.11.2019 Min Body Text Size: 7pt 2. 2. Revision Date: Supplier: Accord Barnstaple 3. 3. Pharmacode: 1668 Revised By: 4. 5. Date Sent: 28/10/19 Proof Round n/a Technical Date sent: 6. 1 Approval Date received: n/a Technologist: T. Hull [email protected] Technically Approved GTIN 13 (if no barcode on artwork): n/a * Please note that only Artwork Studio is permitted to make changes to the above artwork. Version 4 No changes are permitted by any 3rd party other than added notes and mark ups for required changes. 20.11.2019 Dosage • aseptic meningitis can occur in some patients. This may show as a Adults and children over 12 years combination of symptoms such as headache, fever, stiff neck, tiredness, Severe or sudden infections: usually your doctor will prescribe 200mg taken feeling ill and your eyes become very sensitive to bright light twice daily. • kidney problems (signs may include painful urination or blood in the urine) • dizziness, tiredness Long term treatment and prevention therapy: 100mg at night. • convulsions Elderly • involuntary movements Dosage is dependent on kidney function. • pins and needles, shakiness, tremors Elderly patients with kidney problems will usually be prescribed a reduced dose. • ringing in the ears, vertigo • eye redness and pain Children aged 6 – 12 years • increased sensitivity of the skin to the sun Severe or sudden infections: 100mg twice daily. • low blood sugar Long term treatment and prevention therapy: 50mg at night. • low levels of sodium in the blood (may cause nausea, tiredness, muscle The usual dose is around 2mg/kg body weight of the child per day. cramping) • anorexia Children under 6 • depression, anxiety, sleeping difficulties and nightmares This tablet form of Trimethoprim is not recommended for use in children • confusion, hallucinations under 6 years. • joint and muscle ache Your doctor has carefully chosen the correct dosage for you, taking into • shortness of breath, wheezing, nosebleeds account the severity of your condition, your age and any other particular • lupus erythematosus (an auto-immune disorder) reasons special to you. Instructions on how many tablets to take and when to • purple discolorations of the skin take them will be printed on the dispensing label on the pack. • hypersensitivity, anaphylaxis, anaphylactoid reaction drug fever, allergic Never change the dose of your medicine without talking to your doctor first. vasculitis • reduction in numbers of blood cells If you take more of your medicine than you should • elevation of serum transaminases (an indication of liver damage) If you (your child or someone else) take too many tablets, tell a doctor or • elevation of bilirubin levels pharmacist or go to the nearest hospital casualty department straight away. • sore tongue and mouth Remember to take this leaflet and the tablet packaging with you. • anaemia If you forget to take your medicine • sore throat If you do forget to take a dose of your medicine at the correct time, take it as Unknown (frequency cannot be estimated) soon as you remember, then take the next dose at the right time. • pruritus (itching) DO NOT take a double dose. • elevation of serum creatinine and blood urea nitrogen levels If you stop taking your medicine If any side effects get serious, or if you notice any side effects not listed in this Keep taking this medicine until your doctor tells you to stop. Do not stop leaflet, please tell your doctor or pharmacist. taking it just because you feel better. If you stop taking this medicine, your Reporting of side effects condition may re-occur or get worse. If you experience symptoms on stopping If you get any side effects, talk to your doctor, pharmacist or nurse. This includes treatment, contact your doctor. any possible side effects not listed in this leaflet. You can also report side effects If you have any further questions on the use of this medicine, ask your doctor directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search or pharmacist. for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety 4 Possible side effects of this medicine.
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