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DNAJA1 Rabbit pAb

Catalog No.: A3920

Basic Information Background

Catalog No. This encodes a member of the DnaJ family of , which act as heat shock A3920 70 cochaperones. Heat shock proteins facilitate , trafficking, prevention of aggregation, and proteolytic degradation. Members of this family are Observed MW characterized by a highly conserved N-terminal J domain, a glycine/phenylalanine-rich 50kDa region, four CxxCxGxG zinc finger repeats, and a C-terminal substrate-binding domain. The J domain mediates the interaction with 70 to recruit substrates Calculated MW and regulate ATP hydrolysis activity. In humans, this gene has been implicated in 37kDa/44kDa positive regulation of virus replication through co-option by the influenza A virus. Several pseudogenes of this gene are found on other . Category Primary antibody

Applications WB, IHC, FC

Cross-Reactivity Human

Recommended Dilutions Immunogen Information

WB 1:500 - 1:1000 Gene ID Swiss Prot 3301 P31689 IHC 1:50 - 1:100 Immunogen 1:20 - 1:50 FC A synthetic peptide of human DNAJA1

Synonyms DNAJA1;DJ-2;DjA1;HDJ2;HSDJ;HSJ-2;HSJ2;HSPF4;NEDD7;hDJ-2

Contact Product Information

www.abclonal.com Source Isotype Purification Rabbit IgG Affinity purification

Storage Store at 4℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, pH7.3. Validation Data

Western blot analysis of extracts of MCF-7 cells, using DNAJA1 antibody (A3920). Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.

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