Integrating Discovery-Based Research Into the Undergraduate Curriculum: Report of a Convocation
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Scientific Evidence for Effective Teaching of Reading
Read About It: Scientific Evidence for Effective Teaching of Reading Kerry Hempenstall Edited by Jennifer Buckingham Research Report | March 2016 National Library of Australia Cataloguing-in-Publication Data: Creator: Hempenstall, Kerry, author. Title: Read about it : scientific evidence for effective teaching of reading / Kerry Hempenstall ; edited by Jennifer Buckingham. ISBN: 9781922184610? (paperback) Series: CIS research report ; 11. Subjects: Effective teaching. Early childhood education--Research--Australia. Literacy--Research--Australia. Teacher effectiveness. Other Creators/Contributors: Buckingham, Jennifer, editor. Centre for Independent Studies (Australia), issuing body. Dewey Number: 371.10994 Read About It: Scientific Evidence for Effective Teaching of Reading Kerry Hempenstall Edited by Jennifer Buckingham Research Report 11 Related CIS publications Research Report RR9 Jennifer Buckingham and Trisha Jha, One School Does Not Fit All (2016) Policy Magazine Spring Issue Jennifer Buckingham, Kevin Wheldall and Robyn Beaman-Wheldall, ‘Why Jaydon can’t read: The triumph of ideology over evidence in teaching reading’ (2013) Contents Executive Summary ...............................................................................................1 Introduction ..........................................................................................................3 The power of improved instruction ...................................................................4 Effective, evidence-based reading instruction: The five ‘keys’ -
The Role of Histone H2av Variant Replacement and Histone H4 Acetylation in the Establishment of Drosophila Heterochromatin
The role of histone H2Av variant replacement and histone H4 acetylation in the establishment of Drosophila heterochromatin Jyothishmathi Swaminathan, Ellen M. Baxter, and Victor G. Corces1 Department of Biology, Johns Hopkins University, Baltimore, Maryland 21218, USA Activation and repression of transcription in eukaryotes involve changes in the chromatin fiber that can be accomplished by covalent modification of the histone tails or the replacement of the canonical histones with other variants. Here we show that the histone H2A variant of Drosophila melanogaster, H2Av, localizes to the centromeric heterochromatin, and it is recruited to an ectopic heterochromatin site formed by a transgene array. His2Av behaves genetically as a PcG gene and mutations in His2Av suppress position effect variegation (PEV), suggesting that this histone variant is required for euchromatic silencing and heterochromatin formation. His2Av mutants show reduced acetylation of histone H4 at Lys 12, decreased methylation of histone H3 at Lys 9, and a reduction in HP1 recruitment to the centromeric region. H2Av accumulation or histone H4 Lys 12 acetylation is not affected by mutations in Su(var)3-9 or Su(var)2-5. The results suggest an ordered cascade of events leading to the establishment of heterochromatin and requiring the recruitment of the histone H2Av variant followed by H4 Lys 12 acetylation as necessary steps before H3 Lys 9 methylation and HP1 recruitment can take place. [Keywords: Chromatin; silencing; transcription; histone; nucleus] Received September 8, 2004; revised version accepted November 4, 2004. The basic unit of chromatin is the nucleosome, which is guchi et al. 2004). The role of histone variants, and spe- made up of 146 bp of DNA wrapped around a histone cially those of H3 and H2A, in various nuclear processes octamer composed of two molecules each of the histones has been long appreciated (Wolffe and Pruss 1996; Ah- H2A, H2B, H3, and H4. -
TALE-Light Imaging Reveals Maternally Guided, H3k9me2/3-Independent Emergence of Functional Heterochromatin in Drosophila Embryos
Downloaded from genesdev.cshlp.org on September 29, 2021 - Published by Cold Spring Harbor Laboratory Press TALE-light imaging reveals maternally guided, H3K9me2/3-independent emergence of functional heterochromatin in Drosophila embryos Kai Yuan and Patrick H. O’Farrell Department of Biochemistry, University of California at San Francisco, San Francisco, California 94158, USA Metazoans start embryogenesis with a relatively naïve genome. The transcriptionally inert, late-replicating het- erochromatic regions, including the constitutive heterochromatin on repetitive sequences near centromeres and telomeres, need to be re-established during development. To explore the events initiating heterochromatin forma- tion and examine their temporal control, sequence specificity, and immediate regulatory consequence, we estab- lished a live imaging approach that enabled visualization of steps in heterochromatin emergence on specific satellite sequences during the mid-blastula transition (MBT) in Drosophila. Unexpectedly, only a subset of satellite se- quences, including the 359-base-pair (bp) repeat sequence, recruited HP1a at the MBT. The recruitment of HP1a to the 359-bp repeat was dependent on HP1a’s chromoshadow domain but not its chromodomain and was guided by maternally provided signals. HP1a recruitment to the 359-bp repeat was required for its programmed shift to later replication, and ectopic recruitment of HP1a was sufficient to delay replication timing of a different repeat. Our results reveal that emergence of constitutive heterochromatin follows a stereotyped developmental program in which different repetitive sequences use distinct interactions and independent pathways to arrive at a heterochro- matic state. This differential emergence of heterochromatin on various repetitive sequences changes their replica- tion order and remodels the DNA replication schedule during embryonic development. -
Drosophila Ribosomal Proteins Are Associated with Linker Histone H1 and Suppress Gene Transcription
Downloaded from genesdev.cshlp.org on October 2, 2021 - Published by Cold Spring Harbor Laboratory Press Drosophila ribosomal proteins are associated with linker histone H1 and suppress gene transcription Jian-Quan Ni,1,3 Lu-Ping Liu,1,3 Daniel Hess,1 Jens Rietdorf,1 and Fang-Lin Sun1,2,4 1Friedrich Miescher Institute for Biomedical Research, Basel CH-4058, Switzerland; 2Institute of Epigenetics and Cancer Research, School of Medicine, Tsinghua University, Beijing 100080, China The dynamics and function of ribosomal proteins in the cell nucleus remain enigmatic. Here we provide evidence that specific components of Drosophila melanogaster ribosomes copurify with linker histone H1. Using various experimental approaches, we demonstrate that this association of nuclear ribosomal proteins with histone H1 is specific, and that colocalization occurs on condensed chromatin in vivo. Chromatin immunoprecipitation analysis confirmed that specific ribosomal proteins are associated with chromatin in a histone H1-dependent manner. Overexpression of either histone H1 or ribosomal protein L22 in Drosophila cells resulted in global suppression of the same set of genes, while depletion of H1 and L22 caused up-regulation of tested genes, suggesting that H1 and ribosomal proteins are essential for transcriptional gene repression. Overall, this study provides evidence for a previously undefined link between ribosomal proteins and chromatin, and suggests a role for this association in transcriptional regulation in higher eukaryotes. [Keywords: Ribosomal protein; L22; histone H1; chromatin; transcription] Supplemental material is available at http://www.genesdev.org. Received September 25, 2005; revised version accepted May 8, 2006. Transcription and translation in eukaryotes are generally discrete nuclear sites was sensitive to inhibitors of both believed to take place within two spatially separated cel- transcription and translation, arguing that the two pro- lular compartments. -
The Effectiveness of Using Discovery Learning Method in Teaching Writing Skill Viewed from the Students' Creativity
THE EFFECTIVENESS OF USING DISCOVERY LEARNING METHOD IN TEACHING WRITING SKILL VIEWED FROM THE STUDENTS’ CREATIVITY (An Experimental Study at the Tenth Grade Students of SMAN 1 Durenan Trenggalek in the Academic Year of 2014/2015) Thesis Written to Fulfill One of the Requirements to Obtain the Graduate Degree in English Education Written by: Ringgi Candraning Prawerti S 891302037 ENGLISH EDUCATION DEPARTMENT GRADUATE SCHOOL SEBELAS MARET UNIVERSITY SURAKARTA 2014 i APPROVAL THE EFFECTIVENESS OF USING DISCOVERY LEARNING METHOD IN TEACHING WRITING SKILL VIEWED FROM THE STUDENTS’ CREATIVITY (An Experimental Study at the Tenth Grade Students of SMAN 1 Durenan Trenggalek in the Academic Year of 2014/2015) By RINGGI CANDRANING PRAWERTI S891302037 This Thesis has been approved by the consultants of English Education Department Graduate School of Teachers’ Training and Education Faculty of Sebelas Maret University Surakarta in 2014, First consultant, Second consultant, Dr. Ngadiso, M. Pd. Dra. Diah Kristina, M. A, Ph. D NIP. 19621231 198803 1 009 NIP. 19590505 198601 2 001 Approved by The Head of English Education Department Graduate School of Teachers’ Training and Education Faculty of Sebelas Maret University Dr. Abdul Asib, M. Pd NIP. 19520307 198003 1 005 ii LEGITIMATION FROM THE BOARD OF EXAMINERS THE EFFECTIVENESS OF USING DISCOVERY LEARNING METHOD IN TEACHING WRITING SKILL VIEWED FROM THE STUDENTS’ CREATIVITYM By RINGGI CANDRANING PRAWERTI S891302037 This Thesis has been examined by the Board of Thesis Examiners of English Education Department of Teachers Training and Education Faculty of Graduate School of Sebelas Maret University Surakarta on ….., …… Board of Examiners Chairperson : Dr. Abdul Asib, M. -
Introduction to the Genomics Education Partnership and Collaborative Genomics Research in Drosophila
Tested Studies for Laboratory Teaching Proceedings of the Association for Biology Laboratory Education Vol. 34, 135-165, 2013 Introduction to the Genomics Education Partnership and Collaborative Genomics Research in Drosophila Julia A. Emerson1, S. Catherine Silver Key2, Consuelo J. Alvarez3, Stephanie Mel4, Gerard P. McNeil5, Kenneth J. Saville6, Wilson Leung7, Christopher D. Shaffer7 and Sarah C. R. Elgin7 1Amherst College, Department of Biology, P.O. Box 5000, Amherst MA 01002 USA 2North Carolina Central University, Department of Biology, 2246 MTSB, Durham NC 27701 USA 3Longwood University, Department of Biological and Environmental Sciences, 201 High St., Farmville VA 23909 USA 4University of California San Diego, Division of Biological Sciences, 9500 Gilman Drive 0355, La Jolla CA 92093 USA 5York College/CUNY, Department of Biology, 94-20 Guy R. Brewer Blvd., Jamaica NY 11451 USA 6 Albion College, Biology Department, 611 E. Porter St., Albion MI 49224 USA 7Washington University, Department of Biology, Campus Box 1137, One Brookings Dr., St. Louis MO 3130 USA ([email protected]; [email protected]; [email protected]; [email protected]; [email protected]; [email protected]; [email protected]; [email protected]; [email protected]) The GEP, a group of faculty from over 90 primarily undergraduate institutions, is using comparative genomics to engage students in research within regular courses. Using a versatile curriculum, GEP undergraduates undertake projects to improve draft genomic sequences and/or participate in the annotation of these improved sequences. An additional goal of the annotation curriculum is for students to gain a sophisticated understanding of eukaryotic gene structure. Students do so by carefully mapping the protein-coding regions of putative genes from recently- sequenced Drosophila species. -
Workshop Notebook
GCAT WORKSHOPS 2009 NSF SUPPORTED DNA MICROARRAY WORKSHOPS FOR HISTORICALLY BLACK COLLEGES AND UNIVERSITIES, HISPANIC-SERVING INSTITUTIONS AND TRIBAL COLLEGES FACULTY JULY 5 - July 11, 2009 HOST INSTITUTION: MOREHOUSE COLLEGE BIOLOGY DEPARTMENT; ATLANTA, GA INSTRUCTORS Consuelo Alvarez, Malcolm Campbell, Todd Eckdahl, Edison Fowlks, Charles Hauser, Laurie Heyer, and Anne Rosenwald Genome Consortium for Active Teaching (GCAT) NSF GRANT DBI-0520908 Awarded to Hampton University PI: Edison R. Fowlks; Co-PIs: Mary Lee Ledbetter and Anne Rosenwald and NSF GRANT DBI-0520908 Awarded to Davidson College PI: Malcolm Campbell; Co-PIs: Laurie Heyer and Todd Eckdahl By the DIRECTORATE FOR BIOLOGICAL SCIENCES NATIONAL SCIENCE FOUNDATION DR. SALLY O’CONNOR, MANAGERING PROGRAM OFFICER NSF-SPONSORED GCAT DNA MICROARRAY SUMMER WORKSHOPS FOR UNDERGRADUATE HBCU, HSI AND TRIBAL COLLEGE FACULTY TAB I. Origin of this NSF Workshop and History of GCAT 1 II. Workshop Participants and Instructors 2 III. Workshop Schedule of Dry and Wet Lab Activities 3 IV. Assessment Material 4 A. Pre-Test B. Post-Test V. Wet Lab Activities 6 A. Culturing Yeast B. Isolating RNA C. 3DNA Protocol VI. Dry Lab Activities 7 A. Magic Tool User Guide B. Magic Tool: Exploring Diauxic Shift Microarray Data C. Exploring Correlations VII. Sampling of Microarray Articles 7 VIII. Notes, Special Instructions & Directions 8 ORIGIN OF THIS NSF WORKSHOP At a curriculum gathering during summer of 2004, Drs. Fowlks and Campbell presented their perspectives on the undergraduate educational implications of the NIH Roadmap. Fowlks addressed curricular changes in undergraduate biology, as well as recruitment and training for underrepresented populations. Campbell provided an overview of activities by GCAT, a non-profit educational consortium, to bring functional genomics methods into undergraduate courses and independent student research. -
Crossing Boundaries: Transforming Stemeducation
PROJECT KALEIDOSCOPE Advancing What Works in STEM Education NETWORK FOR ACADEMIC RENEWAL CONFERENCE CROSSING BOUNDARIES: TRANSFORMING STEM EDUCATION Westin Seattle | Seattle, Washington November 12-14, 2015 Dear Colleagues, The Association of American Colleges and Universities (AAC&U) and Project Kaleidoscope (PKAL) welcome you to the Network for Academic Renewal conference Crossing Boundaries: Transforming STEM Education. Over the next few days, we invite you to join with colleagues to examine strategies and practices for addressing the national imperative to produce more competitively trained, liberally educated STEM graduates and ensuring a scientifically literate citizenry. Crossing Boundaries provides an opportunity to share and discuss the kinds of integrative, inclusive, and engaging approaches to teaching and learning that all students need to address the pervasive and multifaceted issues of contemporary life. From public health; to climate change; to water, food, and personal security in the midst of geopolitical instability, the program encourages us to collaborate across disciplines, among all campus sectors, and with community and business partners to truly engage students with real-world issues from multiple perspectives. Scott Page, Leonid Hurwicz Collegiate Professor of Complex Systems, Political Science and Economics at the University of Michigan will set the context for the conference by analyzing the ways in which diversity contributes to—indeed is essential for—a high-quality learning environment. Erika Camacho, Associate -
Discovery Learning and Discovery Teaching David Hammer Version of Record First Published: 14 Dec 2009
This article was downloaded by: [SDSU San Diego State University] On: 08 August 2012, At: 09:46 Publisher: Routledge Informa Ltd Registered in England and Wales Registered Number: 1072954 Registered office: Mortimer House, 37-41 Mortimer Street, London W1T 3JH, UK Cognition and Instruction Publication details, including instructions for authors and subscription information: http://www.tandfonline.com/loi/hcgi20 Discovery Learning and Discovery Teaching David Hammer Version of record first published: 14 Dec 2009 To cite this article: David Hammer (1997): Discovery Learning and Discovery Teaching, Cognition and Instruction, 15:4, 485-529 To link to this article: http://dx.doi.org/10.1207/s1532690xci1504_2 PLEASE SCROLL DOWN FOR ARTICLE Full terms and conditions of use: http://www.tandfonline.com/page/terms-and-conditions This article may be used for research, teaching, and private study purposes. Any substantial or systematic reproduction, redistribution, reselling, loan, sub-licensing, systematic supply, or distribution in any form to anyone is expressly forbidden. The publisher does not give any warranty express or implied or make any representation that the contents will be complete or accurate or up to date. The accuracy of any instructions, formulae, and drug doses should be independently verified with primary sources. The publisher shall not be liable for any loss, actions, claims, proceedings, demand, or costs or damages whatsoever or howsoever caused arising directly or indirectly in connection with or arising out of the use of this -
Experiences in Self-Determined Learning
Lisa Blaschke, Chris Kenyon & Stewart Hase (Eds.) Experiences in Self-determinded Learning Copyright © 2014 Lisa Marie Blaschke, Chris Kenyon and Stewart Hase All rights reserved. ISBN: 1502785307 ISBN-13: 978-1502785305 DEDICATION To all the children throughout the world who deserve the best education All proceeds from the sale of this book will be donated to educating children in Africa through Buy1 Give1 ACKNOWLEDGMENTS Thanks to all the contributors who freely gave of their time, effort and knowledge to enable this book Thanks to Amanda Nelson for the cover design A note on spelling: Contributors to this book come from several different countries and use different versions of the English language. The original spelling of a contributor’s work has been unchanged in order to retain the integrity of the work. CONTENTS Biographies ........................................................................ 6 Introduction ...................................................................... 10 The Basics ........................................................................ 14 1 An Introduction to Self-determined Learning (Heutagogy) ............................................................... 15 2 Heutagogy and Systems Thinking: A Perfect Marriage for Conducting Learning Experiences ....... 31 The Learners ..................................................................... 41 3 Embracing Opportunities for Self-directed Learning in Formal Learning Environments .............. 42 4 Moving Students Forward in the PAH Continuum: Maximizing -
Enhancing Students' Motivation and Problem Solving Skills in Mathematics Using Guided Discovery Learning
Universal Journal of Educational Research 8(12): 6783-6789, 2020 http://www.hrpub.org DOI: 10.13189/ujer.2020.081244 Enhancing Students' Motivation and Problem Solving Skills in Mathematics Using Guided Discovery Learning Tanti Diyah Rahmawati1, Dwi Sulisworo2,*, Erwin Prasetyo3 1Department of Mathematics Education, IKIP Muhammadiyah Maumere, Sikka, Indonesia 2Department of Physics Education, Ahmad Dahlan University, Yogyakarta, Indonesia 3Department of Physics Education, IKIP Muhammadiyah Maumere, Sikka, Indonesia Received August 13, 2020; Revised August 17, 2020; Accepted November 12, 2020 Cite This Paper in the following Citation Styles (a): [1] Tanti Diyah Rahmawati, Dwi Sulisworo, Erwin Prasetyo , "Enhancing Students' Motivation and Problem Solving Skills in Mathematics Using Guided Discovery Learning," Universal Journal of Educational Research, Vol. 8, No. 12, pp. 6783 - 6789, 2020. DOI: 10.13189/ujer.2020.081244. (b): Tanti Diyah Rahmawati, Dwi Sulisworo, Erwin Prasetyo (2020). Enhancing Students' Motivation and Problem Solving Skills in Mathematics Using Guided Discovery Learning. Universal Journal of Educational Research, 8(12), 6783 - 6789. DOI: 10.13189/ujer.2020.081244. Copyright©2020 by authors, all rights reserved. Authors agree that this article remains permanently open access under the terms of the Creative Commons Attribution License 4.0 International License Abstract Guided discovery learning is one of the Ability, Mathematics, Guided Discovery, Learning learning models that focus on students. This model is one Strategy, Learning Environment, Learning Innovation, of the recommended models for implementing the 2013 Learning Satisfaction Curriculum as a foundation for education reform in Indonesia. It's just that the internalization of teachers in the learning models that focus on students still needs to be improved. -
Inquiry-Based Learning Literature Review
INQUIRY-BASED LEARNING LITERATURE REVIEW Inquiry-Based Learning: A Review of the Research Literature Dr. Sharon Friesen Galileo Educational Network, University of Calgary David Scott University of Calgary Paper prepared for the Alberta Ministry of Education June 2013 INQUIRY-BASED LEARNING LITERATURE REVIEW 2 Introduction A growing body of research suggests that models of education designed to meet the needs of the industrial past are inadequate for the myriad challenges and opportunities facing 21st century students (Alberta Education, 2010; Barron & Darling-Hammond, 2008; Friesen & Jardine, 2009; Perkins, 2009). New educational environments require different ways of designing learning experiences for students as well as new approaches to teaching and assessment. The call for educational reform away from passive transmission-based learning and the imparting of discrete skills and processes is not new. Institutions of education around the world are reconsidering some of their most deeply-held assumptions about how they conceptualize learning and to what end education should be directed. This shift in thinking has been prominent in Alberta. Subject-specific programs of study and the Ministry of Education’s Inspiring Education (2010) document to guide education in Alberta to 2030 call for a vision of education that will prepare young people for the shifting economic, technological, and socio-political realities of the 21st century. Through fostering intellectual engagement, an entrepreneurial spirit, and the dispositions of ethical citizenship, the vision for education outlined in the Inspiring Education document advocates that students develop competencies through a process of inquiry and discovery. Students would collaborate to create new knowledge while also learning how to “think critically and creatively, and how to make discoveries—through inquiry, reflection, exploration, experimentation, and trial and error” (Alberta Education, 2010, p.