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Wai Ling Kimmy Wu
Wai Ling Kimmy Wu Contact KIPAC/SLAC, 2575 Sand Hill Rd Phone: (650) 804-2550 Information Mailstop 0029 E-mail: [email protected] Fred Kavli Building Website: web.stanford.edu/~wlwu Menlo Park, CA 94025 Current Panofsky Fellow j Associate Scientist September 2020 - present Position SLAC National Accelerator Laboratory, Kavli Institute for Particle Astrophysics and Cosmology Junior research group leader, tenure-track Previous KICP Fellow September 2017 - Aug 2020 Positions University of Chicago, Kavli Institute for Cosmological Physics Croucher Postdoctoral Fellow October 2015 - Aug 2017 University of California, Berkeley Education Stanford University, Stanford, California 2009 - 2015 Ph.D. in Physics, September 2015 Advisor: Chao-Lin Kuo Dissertation: BICEP3 and CMB-S4: current and future CMB polarization experiments to probe fundamental physics University of Michigan { Ann Arbor, Ann Arbor, Michigan 2004 - 2008 B.S. Physics (Highest Honors) B.S. Mathematics Advisor: Timothy McKay University of St Andrews, St Andrews, Scotland 2007 Study Abroad program Research Cosmology, cosmic microwave background, inflation, gravitational lensing, instrumentation Interests Honors and KICP Fellowship, KICP, University of Chicago 2017-2020 Awards Croucher Fellowship, Croucher Foundation 2015-2017 Stanford Science Graduate Fellowship, Stanford University 2011-2013 Allison-Wesley Book Award, University of Michigan Physics Dept. 2008 Phi Beta Kappa 2008 Hellman Family Endowment Award, University of Michigan Honors Program 2006 Sigma Phi Sigma National Physics Honor Society 2006 Frank Sevcik Faculty Award in Physics, University of Michigan Physics Dept. 2005 1 Publications 2550+ citations; h-index = 20; i10-index = 29. 35. F. Bianchini, W. L. K. Wu, et al. [72 authors], \Searching for Anisotropic Cosmic Birefringence with Polarization Data from SPTpol," Phys. -
Carbon Nanotube Biosensors: the Critical Role of the Reference Electrode ͒ Ethan D
APPLIED PHYSICS LETTERS 91, 093507 ͑2007͒ Carbon nanotube biosensors: The critical role of the reference electrode ͒ Ethan D. Minot,a Anne M. Janssens, and Iddo Heller Kavli Institute of Nanoscience, Delft University of Technology, 2628 CJ Delft, The Netherlands Hendrik A. Heering Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands and Kavli Institute of Nanoscience, Delft University of Technology, 2628 CJ Delft, The Netherlands Cees Dekker and Serge G. Lemay Kavli Institute of Nanoscience, Delft University of Technology, 2628 CJ Delft, The Netherlands ͑Received 30 May 2007; accepted 1 August 2007; published online 28 August 2007͒ Carbon nanotube transistors show tremendous potential for electronic detection of biomolecules in solution. However, the nature and magnitude of the sensing signal upon molecular adsorption have so far remained controversial. Here, the authors show that the choice of the reference electrode is critical and resolves much of the previous controversy. The authors eliminate artifacts related to the reference electrode by using a well-defined reference electrode to accurately control the solution potential. Upon addition of bovine serum albumin proteins, the authors measure a transistor threshold shift of −15 mV which can be unambiguously attributed to the adsorption of biomolecules in the vicinity of the nanotube. © 2007 American Institute of Physics. ͓DOI: 10.1063/1.2775090͔ Biosensors based on nanoscale field-effect transistors determining redox couple.13 Sensors for biomolecule binding have the potential to significantly impact drug discovery, dis- are generally operated in buffer solutions where the redox ease screening, biohazard screening, and fundamental species are not controlled and the background redox reac- 1 science. -
Medicine@Yale U
@ MedicineAdvancing Biomedical Science, Education and Health Care YaleVolume 4, Issue 3 July/August 2008 Leading scientist is appointed new chair of Cell Biology Membrane traffi c expert and chair of the School of Medicine’s to Yale’s recently protein-coding genes in the human Department of Cell Biology. Roth- opened West Cam- genome, providing fresh insights into will head a department man will come to Yale from Columbia pus in West Haven, disease and new molecular targets for that has shaped the fi eld University’s College of Physicians and Conn., where he will therapy. Under Rothman’s leadership Surgeons, where he is now a professor launch a Center for the Department of Cell Biology will James E. Rothman, F>:, one of the in the Department of Physiology and High-Throughput be signifi cantly expanded, and will be world’s foremost experts on mem- Biophysics, the Clyde and Helen Wu Cell Biology. At the co-located at the West Campus along brane traffi cking, the means by which Professor of Chemical Biology and new center, multi- with its present location at the main proteins and other materials are director of the Columbia Genome +BNFT3PUINBO disciplinary teams campus of the School of Medicine. transported within and between cells, Center. of scientists will develop tools and For his decades of seminal re- has been named the Fergus F. Wal- In addition to directing Cell techniques to rapidly decipher the cel- search on the transport of molecules lace Professor of Biomedical Sciences Biology, Rothman is the fi rst recruit lular functions of the -
Remembering the Legacy of Fred Kavli
SOCIETY NEWS tion plans to expand the contribution to each institute to about $10 million. “Fred’s contribution to the advance- Remembering ment of science is remarkable and far-reaching, and I am certain future the legacy of generations will owe him a great debt of gratitude for the discoveries that he Fred Kavli encouraged and facilitated,” said Joanna Aizenberg, Director of the Kavli Insti- tute for Bionano Science and Technolo- red Kavli, the founder and chair- gy (KIBST). “Through the Foundation’s Fman of The Kavli Foundation, generous support of KIBST at Harvard passed away in his home in Santa Bar- University, we have been able to explore bara, Calif., on November 21, 2013, at problems that we would never have had the age of 86. an opportunity to explore otherwise. A philanthropist, physicist, entre- In particular, we have pursued early- preneur, business leader, and innovator, stage, high-risk, high-reward research Kavli established The Kavli Founda- that addresses fundamental questions tion in 2000 to advance science for the around the behavior of biomaterials at benefi t of humanity. Based in Southern the nanoscale level. The Institute brings California, the Foundation today in- of Technology, whose research helped together theorists and experimentalists, cludes an international community of usher in the age of nanotechnology. as well as clinicians, across a wide range basic research institutes in the fi elds of “His greatest contribution to science of interdisciplinary areas.” astrophysics, nanoscience, neurosci- was setting up a foundation incorpo- “Fred Kavli was a man with great ence, and theoretical physics. Located rating his wisdom and money. -
Nanofabricated Structures and Microfluidic Devices for Bacteria: from Techniques to Biology Cite This: DOI: 10.1039/C5cs00514k Fabai Wu and Cees Dekker*
Chem Soc Rev View Article Online TUTORIAL REVIEW View Journal Nanofabricated structures and microfluidic devices for bacteria: from techniques to biology Cite this: DOI: 10.1039/c5cs00514k Fabai Wu and Cees Dekker* Nanofabricated structures and microfluidic technologies are increasingly being used to study bacteria because of their precise spatial and temporal control. They have facilitated studying many long-standing questions regarding growth, chemotaxis and cell-fate switching, and opened up new areas such as probing the effect of boundary geometries on the subcellular structure and social behavior of bacteria. Received 30th June 2015 We review the use of nano/microfabricated structures that spatially separate bacteria for quantitative DOI: 10.1039/c5cs00514k analyses and that provide topological constraints on their growth and chemical communications. These approaches are becoming modular and broadly applicable, and show a strong potential for dissecting www.rsc.org/chemsocrev the complex life of bacteria at various scales and engineering synthetic microbial societies. Key learning points (1) Microfabricated structures can spatially isolate and separate bacteria for single-cell analyses, for drug discovery by cultivating natural species on chips, and for lineage tracking that reveals the rules governing cell growth, cell-fate decisions, and antibiotic resistance. (2) Microfluidic devices that separate bacteria with semipermeable materials allow dissecting the effect of chemical communication between bacteria that exchange metabolic -
The Kavli Prize Laureate Lecture
The Kavli Prize Laureate Lecture 24 April 2013, 17:00 – 20:00 The Nordic Embassies in Berlin, Rauchstraße 1, 10787 Berlin-Tiergarten In co-operation with: Berlinffff The Kavli Prize is a partnership between The Norwegian Academy of Science and Letters, The Kavli Foundation and The Norwegian Ministry of Education and Research Programme: 16:30 Registration Please be seated by 16:55 17:00 Welcome Sven E. Svedman, Norwegian Ambassador to Germany 17:05 ”The Kavli Prize: fostering scientific excellence and international cooperation” Ms Kristin Halvorsen, Norwegian Minister of Education and Research 17:20 „Internationale Herausforderungen – internationale Kooperationen: Der Auftrag der Wissenschaft“ Prof. Dr. Johanna Wanka, Federal Minister of Education and Research 17:35 Short remarks Prof. Dr. Herbert Jäckle, Vice President of the Max Planck Society 17:40 Short remarks Professor Kirsti Strøm Bull President of The Norwegian Academy of Science and Letters 17:45 Lecture: “Following the Brain’s Wires” Kavli Prize Laureate Prof. Dr. Winfried Denk Max Planck Institute for Medical Research, Heidelberg 18:10 Lecture: “Towards an Understanding of Neural Codes” Prof. Dr. Gilles Laurent Director of the Max Planck Institute for Brain Research, Frankfurt 18:35 Reception Exhibition Hall of the Nordic Embassies in Berlin “Following the Brain’s Wires” Kavli Prize Laureate Prof. Dr. Winfried Denk To understand neural circuits we need to know how neurons are connected. Over the past decade we have developed methods that allow the reconstruction of neural wiring diagrams via the acquisition and analysis of high-resolution three-dimensional electron microscopic data. We have applied these methods to the retina in order to explore, for example, how direction-selective signals are computed. -
Simultaneous Electrical Transport and Scanning Tunneling Spectroscopy
NANO LETTERS xxxx Simultaneous Electrical Transport and Vol. 0, No. 0 Scanning Tunneling Spectroscopy of A-E Carbon Nanotubes Brian J. LeRoy,*,† Iddo Heller, Vijay K. Pahilwani, Cees Dekker, and Serge G. Lemay KaVli Institute of Nanoscience, Delft UniVersity of Technology, Lorentzweg 1, 2628 CJ Delft, The Netherlands Received April 5, 2007; Revised Manuscript Received May 22, 2007 ABSTRACT We performed scanning tunneling spectroscopy measurements on suspended single-walled carbon nanotubes with independently addressable source and drain electrodes in the Coulomb blockade regime. This three-terminal configuration allows the resistance to the source and drain electrodes to be individually measured, which we exploit to demonstrate that electrons were added to spin-degenerate states of the carbon nanotube. Unexpectedly, the Coulomb peaks also showed a strong spatial dependence. By performing simultaneous scanning tunneling spectroscopy and electrical transport measurements we show that the probed states are extended between the source and drain electrodes. This indicates that the observed spatial dependence reflects a modulation of the contact resistance. Single-walled carbon nanotubes (SWCNTs) have extremely growing SWCNTs directly on Pt electrodes separated by a promising electrical transport properties. In a field-effect trench.10 A 100 nm trench was etched in a Si wafer with a transistor geometry, they have been shown to have a higher 250 nm SiO2 layer to create the separation between the two drive current and transconductance than can be found in Si Pt electrodes which were used as the source and drain devices.1 However, one of the major unresolved issues is electrode. 8 µm × 5 µm regions were defined by electron- the influence of the contacts on their transport properties.2-4 beam lithography at a distance of 1.5 µm from the trench. -
A NSF Physics Frontier Center Annual Report 2005-2006
A NSF Physics Frontier Center Annual Report 2005-2006 June 29, 2006 i Table of Contents 1 Executive Summary 1 2 Research Accomplishments and Plans 4 2.a Major Research Accomplishments . 4 2.a.1 Research Highlights . 4 2.a.2 Detailed Research Activities: MRC I- Theory . 5 2.a.3 Detailed Research Activities: MRC II- Structures in the Uni- verse ..................................... 20 2.a.4 Detailed Research Activities: MRC III - Cosmic Radiation Backgrounds ................................ 24 2.a.5 Detailed Research Activities: MRC IV - Particles from Space . 28 2.a.6 References . 32 2.b Research Organizational Details . 33 2.c Plans for the Coming Year . 33 3 Publications, Awards and Technology Transfers 40 3.a List of Publications in Peer Reviewed Journals . 40 3.b List of Publications in Peer Reviewed Conference Proceedings . 48 3.c Invited Talks by Institute Members . 52 3.d Honors and Awards . 56 3.e Technology Transfer . 57 4 Education and Human Resources 58 4.a Graduate and Postdoctoral Training . 58 4.a.1 Research Training . 58 4.a.2 Curriculum Development: . 62 4.b Undergraduate Education . 63 4.b.1 Undergraduate Research Experiences: . 63 4.b.2 Undergraduate Curriculum Development: . 64 4.c Educational Outreach . 65 4.c.1 K-12 Programs: Space Explorers . 66 4.c.2 Web-Based Educational Activities: . 69 4.c.3 Other: . 69 4.d Enhancing Diversity . 72 5 Community Outreach and Knowledge Transfer 74 5.a Visitor Participation in Center . 74 5.a.1 Long term visitors . 74 5.a.2 Short term and seminar visitors . 75 5.b Workshops and Symposia . -
Raymond Wilson Honoured with Two Prestigious Prizes
Astronomical News Raymond Wilson Honoured with Two Prestigious Prizes Jeremy Walsh1 1 ESO Ray Wilson, who retired from ESO in 1993, was awarded two prestigious prizes in September 2010 for his out standing work on telescope optics: the Kavli Prize in the field of astrophysics and the Tycho Brahe Prize 2010 of the European Astronomical Society. Announced in June 2010, and awarded in Stockholm in September, the million dollar Kavli Prizes were awarded to eight scientists “whose discoveries have dramatically expanded human under standing in the fields of astrophysics, nano science and neuroscience” (see the Kavli press release1). The Kavli prize is awarded by the Norwegian Academy of Science and Letters, the Kavli Foundation and the Norwegian Ministry of Educa- tion and Research. The Kavli Foundation VLT and the 42-metre ELT: the develop Figure 1. Ray Wilson receiving the Tycho Brahe prize is funded by Fred Kavli, the Norwegian ment of active optics as the basis of from the president of the EAS at the JENAM meeting in Lisbon, Portugal. entrepreneur and philanthropist who later all modern telescope optics”. Figure 1 founded the Kavlico Corporation in shows Ray receiving the Tycho Brahe the US — today one of the world’s largest prize from the retiring president of the During his last years at ESO he began suppliers of sensors for aeronautical, EAS, Joachim Krautter. work on his magnum opus, the twovol automotive and industrial applications. ume work Reflecting Telescope Optics, There were three recipients in astro Ray Wilson, who was born in England published by Springer 5. Volume I: Basic physics, all acclaimed for their work on and educated at Birmingham University Design Theory and Its Historical Develop- the development of giant optical tele and Imperial College London, arrived at ment, first appeared in 1996, and Volume scopes2 — Roger Angel of the University ESO in 1972 from Zeiss at Oberkochen, II: Manufacture, Testing, Alignment, Mod- of Arizona, Tucson, attached to Steward Germany where he had been head of the ern Techniques followed in 1999. -
Nanotechnology in the EU – Bioanalytical and Biodiagnostic Techniques
Nanotechnology in the EU – Bioanalytical and Biodiagnostic Techniques. September 2004 1 Nanotechnology in the EU – Bioanalytical and Biodiagnostic Techniques A Nanoforum report, available for download from www.nanoforum.org. Author Christof Ruch Editor Mark Morrison 2 Nanotechnology in the EU – Bioanalytical and Biodiagnostic Techniques Nanotechnology in the EU – Bioanalytical and Biodiagnostic Techniques ...... 2 1 Object of this report ...................................................................... 5 2 About Nanoforum.......................................................................... 6 2.1 What is nanotechnology? ............................................................. 7 2.2 Present and future of nanotechnology in diagnostics and analytics ..... 7 2.3 Key techniques and equipment ..................................................... 9 2.3.1 Arrays/biochips .................................................................... 9 2.3.2 Lab-on-a-chip .................................................................... 12 2.3.3 Imaging ............................................................................ 13 2.3.4 Metrology .......................................................................... 15 2.3.4.1 Scanning Probe Microscopes........................................... 15 2.3.4.2 Quantum Dots.............................................................. 16 2.3.4.3 Surface Plasmon Resonance ........................................... 18 3 European Initiatives ................................................................... -
Science on All Scales
NEWS & VIEWS chosen collective coordinate of the atomic towards a potentially fruitful interplay of References cloud replaces the position of the end- cold-atom physics with concepts known in 1. Höhberger-Metzger, C. & Karrai, K. Nature 432, 1002–1005 (2004). 2. Gigan, S. et al. Nature 444, 67–70 (2006). mirror in the standard set-up. One of the nano- and optomechanics. Exciting avenues 3. Arcizet, O., Cohadon, P. F., Briant, T., Pinard, M. & Heidmann, A. benefits provided by this scheme is that to be explored are the role of interatomic Nature 444, 71–74 (2006). there is no need to work hard to get to the interactions (giving rise to truly collective 4. Kleckner, D. & Bouwmeester, D. Nature 444, 75–78 (2006). 5. Schliesser, A., Del’Haye, P., Nooshi, N., Vahala, K. J. ground state. In fact, in the direction along modes) and the combination with atom- & Kippenberg, T. J. Phys. Rev. Lett. 97, 243905 (2006). the cavity axis, the vibrational motion of chip techniques. 6. Corbitt, T. et al. Phys. Rev. Lett. 98, 150802 (2007). the atoms is already in the ground state, Different as the two approaches9,10 may 7. Thompson, J. D. et al. Nature 452, 72–75 (2008). 8. Schwab, K. C. & Roukes, M. L. Phys. Today 36–42 (July 2005). at microkelvin temperatures. The atoms’ be, they illustrate the rapid pace of progress 9. Regal, C. A., Teufel, J. D. & Lehnert, K. W. Nature Phys. vibrations have a rather low quality factor, in the young field of optomechanics. 4, 555–560 (2008). but this is actually useful for observing Breakthroughs such as cooling of massive 10. -
Curriculum Vitae Derek Stein
Curriculum Vitae Derek Stein 1. NAME, POSITION, AND DEPARTMENT Derek Stein Associate Professor Department of Physics and School of Engineering 2. WORK ADDRESS 182 Hope Street Providence, RI, 02912 USA 3. EDUCATION Ph.D. (Applied Physics) Harvard University, 2003 Dissertation topic: Ion Beam Sculpting Molecular-Scale Devices M.Sc. (Applied Physics) Harvard University, 1998 B.Sc. (Physics, Honours) McGill University, 1997 B.Sc. Candidate (Physics) Queen’s University (Canada), 1993 – 1994 4. PROFESSIONAL APPOINTMENTS 2014 – present Brown University, Department of Physics and School of Engineering Associate Professor 2014 Ecole Normale Superieure de Paris, Laboratoire de Physique Statistique Visiting Professor 2013 – 2014 Brown University, Department of Physics Associate Professor 2011 – 2013 Brown University, Department of Physics Manning Assistant Professor 2006 – 2011 Brown University, Department of Physics Assistant Professor 2003 – 2006 Delft University of Technology, Kavli Institute of Nanoscience Postdoctoral research in the group of Cees Dekker 2002 Agilent Technologies, Life Sciences Technologies Laboratory Nanopore technology transfer from Ph.D. research 1998 – 2002 Harvard University, Division of Engineering and Applied Sciences Research Fellow in the group of Jene Golovchenko 1993 – 1997 Merck-Frosst Canada, Pharmaceutical Research and Development Summer research projects 5. COMPLETED PUBLICATIONS b. Chapters in books 1. “Ion, Polymer, and Biomolecule Transport in the Nanofluidic Regime”, Derek Stein, Mar- tin van den Heuvel and Cees Dekker, in: Nanofluidics: Nanoscience and Nanotechnology, Joshua Edel and Andrew de Melo, Eds. Royal Society of Chemistry, London, (2009). 2. “Passive and Electrically Actuated Solid-State Nanopores for Sensing and Manipulating DNA”, Zhijun Jiang, Mirna Mihovilovic, Erin Teich, and Derek Stein, in: Nanopore-based technology: Single molecule characterization and DNA sequencing, M.E.