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BIOINFORMATICS MARKET BY SECTOR (MOLECULAR MEDICINE, AGRICULTURE, FORENSIC, ANIMAL, RESEARCH & GENE THERAPY), SEGMENT (SEQUENCING PLATFORMS, KNOWLEDGE MANAGEMENT & DATA ANALYSIS) & APPLICATION (GENOMICS, PROTEOMICS & METABOLOMICS) GLOBAL FORECAST TO 2020

MARKETSANDMARKETS [email protected] It ’s a ll a b o u t m a rke ts www.marketsandmarkets.com

Bioinformatics Market – Global Forecast To 2020

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1 INTRODUCTION

1.1 MARKET DEFINITION Bioinformatics is the application of computer technology for the management and analysis of biological data.

1.2 MARKET SCOPE

BIOINFORMATICS MARKET

Sectors Products & Services Applications Regions

Knowledge Management Medical Biotechnology Genomics North America Tools

Chemoinformatics & Academics Platforms Europe Drug Design

Animal Biotechnology Services Proteomics APAC

Agricultural Transcriptomics RoW Biotechnology

Environmental Metabolomics Biotechnology

Forensic Biotechnology Molecular Phylogenetics

Others* Others**

Others** include Glycomics, Cytomics, Physiomics, and Interactomics Others* include Home Land Security and Defence, Law Enforcement Groups, Bioweapon Creation, and Evolutionary Biotechnology

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2 RESEARCH METHODOLOGY

2.1 MARKET BREAKDOWN AND DATA TRIANGULATION FIGURE 1 DATA TRIANGULATION METHODOLOGY

PRIMARY SOURCES SECONDARY SOURCES

Interviews with: Annual Reports, Presentations, • Researchers Websites and Press Releases • Bioinformatics Technicians of Top Players, News Articles, • Purchase Managers in MnM KNOW* Journals, and Paid Databases Academics and Pharmaceutical &

Demand Side Demand Biotechnology Companies • Genome Canada (PEC) • National Institute of health (NIH) Interviews with: Primary Secondary • CEOs Sources Sources • World Health Organization (WHO) • Vice Presidents • National Human genome Research • Marketing Directors DATA TRIANGULATION Institute • Technology and Innovation Directors and Related Key Executives from Various Key

Supply Side Supply Companies and Organizations Operating in the Bioinformatics Market Information Sourced

Opportunities and Market Size (2014) and Key Players Competitive Landscape Challenges Market Share (2014)

Drivers and Restraints Forecast Geographical Analysis

MnM KNOW* stands for ‘MarketsandMarkets Knowledge Asset Management' framework. In this context, it stands for the existing market research knowledge repository of over 5,000 granular markets, our flagship competitive intelligence and market research platform "RT", subject-matter experts, and independent consultants. MnM KNOW acts as an independent source that helps us validate information gathered from primary and secondary sources .

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2.1.1 KEY DATA FROM SECONDARY SOURCES

PARAMETER SECONDARY SOURCES

. Company Financials . Magazines . Journals 1 Market Size . Press Releases . Paid Databases . MarketsandMarkets Data Repository

. Annual Reports Revenue . Company Websites 2 of Companies . Public Databases . MarketsandMarkets Data Repository

. Company Websites Qualitative Information . Annual Reports 3 (Market Dynamics and Trends) . Press Releases . MarketsandMarkets Data Repository

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3 PREMIUM INSIGHTS

3.1 GLOBAL BIOINFORMATICS MARKET, BY PRODUCTS AND SERVICES

FIGURE 2 BIOINFORMATICS PLATFORMS SEGMENT IS EXPECTED TO DOMINATE THE MARKET

CAGR% CAGR% CAGR% Market Size 2020 (2015–2020) (2015–2020) (2015-2020) ($Million)

North America XX XX XX

Europe XX XX XX

Asia-Pacific XX XX XX

Knowledge Management Tools

RoW Bioinformatics Platforms XX XX XX

Bioinformatics Services

Source: Annual Reports, SEC Filings, Press Releases, Investor Presentations, Oxford Journals, National Human Genome Research Institute (NHGRI), EMBL-European Bioinformatics Institute (EMBL-EBI), National Center for Biotechnology Information (NCBI), Genome Canada, Expert Interviews, and MarketsandMarkets Analysis

3.2 GLOBAL BIOINFORMATICS MARKET, BY APPLICATION

FIGURE 3 GENOMICS SEGMENT OFFERS LUCRATIVE GROWTH OPPORTUNITIES

Market Size ($Million) XX% 4,500.0

2014 4,000.0 XX% XX% 2020 3,500.0 CAGR% (2015–2020) 3,000.0

2,500.0

2,000.0 XX%

1,500.0 XX XX% XX XX XX% 1,000.0 XX% XX 500.0 XX XX XX XX XX XX XX XX XX XX 0.0 Genomics Chemoinformatics Proteomics Transcriptomics Metabolomics Molecular Others & Drug Design Phylogenetics

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4 MARKET OVERVIEW

4.1 MARKET DYNAMICS

4.1.1 DRIVERS

4.1.1.1 Growing demand for nucleic acid and protein sequencing

Bioinformatics is increasingly being used to identify genes on the DNA sequence. The information collected is used to understand the molecular mechanisms of the disease. This assists in developing better treatments, cures, as well as preventative tests. Previously, sequencing-related projects were not affordable to small research centers and companies due to the high cost of sequencing. However, due reduced costs, many scientific research institutes and biotech companies have taken initiatives to perform sequencing studies. Similarly, sequencing can now be completed within months after the development of bioinformatics tools. As the speed of decoding genetic sequences has increased, the overall cost of sequencing also decreased from 10 dollars per base in 1990 to 10 cents per base by 2003. As a result, the number of companies participating in DNA sequencing projects is increasing owing to reduced costs. This is driving the growth of the bioinformatics market.

4.1.1.2 Increasing funding from government and private organizations Government and private organizations are increasingly investing in the field of bioinformatics to further develop the understanding of the human and microbial genome at the molecular level. In this regard, in April 2013, the Canadian government invested $XX million to enhance bioinformatics and computational biology tools and methodologies which are used in genomics research. This funding helped develop tools for providing better treatments to treat cancer.

4.1.1.3 Rising initiatives by research institutes Initiatives taken by research institutes to provide training for the use of bioinformatics are contributing to the growth of market. For instance, in 2014, Intelligent Systems for Molecular Biology (ISMB) conducted a training in Boston(U.S.) which included computational biologists working and running bioinformatics core facilities. Similarly, in February 2013, the European Bioinformatics Institute, Cambridge (U.K.) initiated the European Molecular Biology Organization (EMBO)practical course on new techniques in metabolomics and usage of various bioinformatics tools. This course aimed to improve ability of researchers to perform researches related with metabolomics and bioinformatics.

4.1.1.4 Increasing information technology (IT) support Over the last few years, there have been many partnerships signed between IT and bioinformatics companies. These partnerships aimed to facilitate the development of bioinformatics tools and databases. In April 2013, Integromics (Spain), the Leibniz Supercomputing Centre in Munich-LRZ (Germany), the Johannes Kepler University of Linz-JKU (Austria), RISC Software (Austria), and Carlos Haya Hospital (Spain) synergized to form a new association for the development of IT solutions. The purpose of this association was to further develop bioinformatics services involved in the analysis and management of macro-datasets produced from genomics research. This association also assists clinical applications based on macro datasets. Thus, growing IT support for the development of bioinformatics is significantly contributing to the growth of bioinformatics market.

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4.1.1.5 Growing applications of bio informatics in drug discovery and development Bioinformatics has emerged as a key tool to manage the data generated during the drug discovery and development processes, starting from preclinical trials to target identification and throughput screening. According to California Biomedical Research Association, on an average, an entire new drug development process takes around 12 years. Additionally, only 5 in XX or XX% of the drugs under preclinical testing make it through the drug development process, annually. On an average, a pharma company invests ~$XX million in the new drug development process. Emergence of bioinformatics has shortened the 12-year drug-development process to four or five years.

Beside this, the use of human genome sequencing in human clinical trials have curtailed one-tenth of the costs incurred in drug discovery. Thus, increasing applications of bioinformatics in the drug discovery and development processes drive the market growth.

8 © MarketsandMarkets Sample Pages POINT-OF-CARE DIAGNOSTICS MARKET

[(Products – Glucose Monitoring & Infectious Diseases Testing Kits, Cardiac & Tumor Markers), (End Users – Self & Professional Monitoring), (Over –the- Counter & Prescription Based)]

– Global Forecast to 2018]

Bioinformatics Market – Global Forecast To 2020

5 INDUSTRY TRENDS

5.1 PORTER’S FIVE FORCES ANALYSIS The competitive environment prevailing in the industry can be analyzed through Porter’s Five Forces analytical framework.

FIGURE 4 PORTER’S FIVE FORCES ANALYSIS

Threat of Substitutes (Low) Intensity of

Bargaining Power Bargaining of Suppliers Intensity of Rivalry Power of Buyers (High) (Low) (Moderate-to-High)

Threat from New Entrants (Moderate)

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6 BIOINFORMATICS MARKET, BY PRODUCTS AND SERVICES

6.1 BIOINFORMATICS PLATFORMS

6.1.1 SEQUENCE MANIPULATION PLATFORMS TABLE 1 SEQUENCE MANIPULATION PLATFORMS MARKET SIZE, BY REGION, 2013–2020 ($MILLION)

CAGR% Region 2013 2014 2015-e 2020-p (2015–2020)

North America XX XX XX XX XX

Europe XX XX XX XX XX

APAC XX XX XX XX XX

RoW XX XX XX XX XX

Total XX XX XX XX XX

In 2014, North America accounted for the largest share of the sequence alignment platforms market. This regional segment is poised to reach $XX million by 2020 from $XX million in 2015, at a CAGR of XX% during the forecast period.

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7 BIOINFORMATICS MARKET, BY APPLICATION

7.1 GENOMICS TABLE 2 GENOMICS MARKET SIZE, BY REGION, 2013–2020 ($MILLION)

CAGR% Region 2013 2014 2015-e 2020-p (2015–2020)

North America XX XX XX XX XX

Europe XX XX XX XX XX

APAC XX XX XX XX XX

RoW XX XX XX XX XX

Total XX XX XX XX XX

e - Estimated; p – Projected Source: Annual Reports, SEC Filings, Press Releases, Investor Presentations, Oxford Journals, National Human Genome Research Institute (NHGRI), EMBL-European Bioinformatics Institute (EMBL-EBI), National Center for Biotechnology Information (NCBI), Genome Canada, Expert Interviews, and MarketsandMarkets Analysis

In 2014, North America accounted for the largest share of the global genomics applications market. This regional segment is poised to reach $XX million by 2020 from $XX million in 2015, at a CAGR of XX% during the forecast period.

TABLE 3 NORTH AMERICA: GENOMICS MARKET SIZE, BY COUNTRY, 2013–2020 ($MILLION)

CAGR% Country 2013 2014 2015-e 2020-p (2015–2020)

U.S. XX XX XX XX XX

Canada XX XX XX XX XX

Total XX XX XX XX XX

In 2014, the U.S accounted for the largest share of the genomics applications market in North America. This regional segment is poised to reach $XX million by 2020 from $XX million in 2015, at a CAGR of XX% during the forecast period

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TABLE 4 APAC: GENOMICS MARKET SIZE, BY COUNTRY/ REGION, 2013–2020 ($MILLION)

CAGR% Country/Region 2013 2014 2015-e 2020-p (2015–2020)

India XX XX XX XX XX

China XX XX XX XX XX

RoAPAC XX XX XX XX XX

Total XX XX XX XX XX

In 2014, India accounted for the largest share of the APAC genomics applications market. This regional segment is poised to reach $XX million by 2020 from $XX million in 2015, at a CAGR of XX% during the forecast period.

8 BIOINFORMATICS MARKET, BY REGION

8.1 EUROPE TABLE 5 EUROPE : BIOINFORMATICS MARKET SIZE, BY PRODUCTS AND SERVICES, 2013–2020 ($MILLION)

CAGR% Products & Services 2013 2014 2015-e 2020-p (2015–2020)

Knowledge Management Tools XX XX XX XX XX

Bioinformatics Platforms XX XX XX XX XX

Bioinformatics Services XX XX XX XX XX

Total XX XX XX XX XX

e – Estimated, p – Projected Source: Annual Reports, SEC Filings, Press Releases, Investor Presentations, Oxford Journals, National Human Genome Research Institute (NHGRI), EMBL-European Bioinformatics Institute (EMBL-EBI), National Center for Biotechnology Information (NCBI), Genome Canada, Expert Interviews, and MarketsandMarkets Analysis

In 2014, the knowledge management tools segment accounted for the largest share of the bioinformatics products and services market in Europe. This segment is poised to reach $XX million by 2020, at a CAGR of XX% from 2015 to 2020.

TABLE 6 EUROPE: BIOINFORMATICS MARKET SIZE, BY KNOWLEDGE MANAGEMENT TOOL, 2013–2020 ($MILLION)

CAGR% Product 2013 2014 2015-e 2020-p (2015–2020)

Generalized Management Tools XX XX XX XX XX

Specialized Management Tools XX XX XX XX XX

Total XX XX XX XX XX

In 2014, the generalized management tools segment accounted for the largest share of the knowledge management tools market in Europe. This segment is poised to reach $XX million by 2020, at a CAGR of XX% from 2015 to 2020.

TABLE 7 EUROPE: BIOINFORMATICS MARKET SIZE, BY PLATFORM, 2013–2020 ($MILLION)

CAGR% Platform 2013 2014 2015-e 2020-p (2015–2020)

Sequence Analysis XX XX XX XX XX

Sequence Alignment XX XX XX XX XX

Sequence Manipulation XX XX XX XX XX Structural & Functional Analysis Platforms XX XX XX XX XX Others XX XX XX XX XX

Total XX XX XX XX XX

In 2014, the sequence analysis segment accounted for the largest share of the bioinformatics platforms market in Europe. This segment is poised to reach $XX million by 2020, at a CAGR of XX% from 2015 to 2020.

9 COMPETITIVE LANDSCAPE

9.1 MARKET SHARE ANALYSIS, BIOINFORMATICS MARKET The bioinformatics market was dominated by four players—Illumina (U.S.), Thermo Fisher Scientific, Inc. (U.S.), QIAGEN (Netherlands), and Agilent Technologies (U.S.), with market shares of XX%, XX%, XX%, and XX%, respectively. These companies together accounted for XX% of the total market. Other players in this market were Affymetrix, Biomax Informatics, ID Business Solutions, among others, which together accounted for ~XX% of this market.

FIGURE 5 BIOINFORMATICS MARKET, BY KEY PLAYERS 2014

• Leader in bioinformatics market • Others includes • Launched MiSeq FGx Forensic Genomics Affymetrix, Biomax System and the HiSeq X Five System and Informatics, and ID the HiSeq 3000/4000 Systems. Business Solutions. They accounted for • Agreement with Laboratory Corporation of ~XX% of this market America Holdings (LabCorp)(U.S.) and Quest Diagnostics (U.S.)

XX% ABC DEF XX% • Top 4 companies GHI accounted for XX% of the XX% IJK bioinformatics MNO market XX% XX%

• Held the second position in the market • Extensive product portfolio • Launched innovative products, such as GeneRead DNAseq V2 gene panels

Source: Press Releases, Expert Interviews, and MarketsandMarkets Analysis

9.2 NEW PRODUCT LAUNCHES TABLE 8 NEW PRODUCT LAUNCHES, 2012–2015

Date Company Name Development Market Importance

Agilent Technologies, Inc. launched the LC Dissolution Software, a new module used with the Agilent ChemStation Edition of the Agilent OpenLAB August 2012 Technologies (U.S.) Chromatography Data System. The software enabled users to minimize investments in exporting data to spreadsheets and simplified the quantification and reporting of dissolution samples interpreted by HPLC. Agilent introduced the SureDesign, a new online interface for researchers to develop customized Agilent target-enrichment panels for next-generation August 2012 Technologies (U.S.) sequencing (NGS). This launch enabled the company to further design customized panels for the targeted resequencing of genes locations to identify mutations associated with congenital disease. Illumina, Inc. launched the MiSeq FGx Forensic Genomics System, the first fully validated forensic NGS system. This system allowed accurate analysis August 2012 Illumina (U.S.) of a wide range of genetic markers and the reliable analysis of forensic DNA samples. Through this launch, the company expanded its product portfolio of forensic genomics systems. Illumina launched the HiSeq X Five System and the HiSeq XX/XX Systems. These products are August 2012 Illumina (U.S.) technologically developed, reasonable in price, and enable greater productivity. This expanded the company’s portfolio of NGS systems. Illumina launched the TruSight One Sequencing Panel, the industry’s broadest sequencing panel capable of targeting XX genes with known associated August 2012 Illumina (U.S.) clinical phenotypes. The benefits of this panel include increased productivity, reduced handling errors, and decreased cost. The launch broadened the company’s NGS product catalog. Illumina launched the BaseSpace apps enhanced with BaseSpace iCredits e-commerce transactions. August 2012 Illumina, Inc. (U.S.) The product enables clients to quickly and easily buy Illumina and third-party bioinformatics applications

(apps). This launch will help the company broaden its customer base for Illumina’s bioinformatics tools.

QIAGEN QIAGEN launched 14 new GeneRead DNAseq V2 August 2012 (Netherlands) gene panels. This expanded the company’s product portfolio.

Source: Press Releases

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