Rabbit Anti-Human SMARCAL1 Polyclonal Antibody (DPABH-17310) This product is for research use only and is not intended for diagnostic use.
PRODUCT INFORMATION
Target Human SMARCAL1
Immunogen Immunogen range: Between 904 and 954
Isotype IgG
Source/Host Rabbit
Species Reactivity Human
Purification Affinity Purified
Conjugate Unconjugated
Applications WB, IP
Format Liquid
Concentration Lot specific
Buffer Tris-citrate/phosphate buffer, pH 7 to 8
Preservative 0.09% Sodium Azide
Storage 2 - 8° C. 1 year from date of receipt
Ship Wet ice
Warnings For research use. Centrifuge before opening to ensure complete recovery of vial contents. To use under sterile conditions.
BACKGROUND
Introduction The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein shows sequence similarity to the E. coli RNA polymerase-binding protein HepA. Mutations in this
45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]
Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved gene are a cause of Schimke immunoosseous dysplasia (SIOD), an autosomal recessive disorder with the diagnostic features of spondyloepiphyseal dysplasia, renal dysfunction, and T- cell immunodeficiency.
Keywords SMARCAL1;SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1;ATP driven annealing helicase;HARP;HepA related protein;HHARP;HepA-related protein;SMARCA-like protein 1;ATP-driven annealing helicase
GENE INFORMATION
Gene Name SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1
Official Symbol SMARCAL1
Entrez Gene ID 50485
UniProt ID Q9NZC9
45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]
Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved