Rabbit Anti-Human SMARCAL1 Polyclonal Antibody (DPABH-17310) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Target Human SMARCAL1

Immunogen Immunogen range: Between 904 and 954

Isotype IgG

Source/Host Rabbit

Species Reactivity Human

Purification Affinity Purified

Conjugate Unconjugated

Applications WB, IP

Format Liquid

Concentration Lot specific

Buffer Tris-citrate/phosphate buffer, pH 7 to 8

Preservative 0.09% Sodium Azide

Storage 2 - 8° C. 1 year from date of receipt

Ship Wet ice

Warnings For research use. Centrifuge before opening to ensure complete recovery of vial contents. To use under sterile conditions.

BACKGROUND

Introduction The encoded by this is a member of the SWI/SNF family of . Members of this family have and ATPase activities and are thought to regulate transcription of certain by altering the chromatin structure around those genes. The encoded protein shows sequence similarity to the E. coli RNA polymerase-binding protein HepA. Mutations in this

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Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved gene are a cause of Schimke immunoosseous dysplasia (SIOD), an autosomal recessive disorder with the diagnostic features of spondyloepiphyseal dysplasia, renal dysfunction, and T- cell immunodeficiency.

Keywords SMARCAL1;SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1;ATP driven annealing helicase;HARP;HepA related protein;HHARP;HepA-related protein;SMARCA-like protein 1;ATP-driven annealing helicase

GENE INFORMATION

Gene Name SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1

Official Symbol SMARCAL1

Entrez Gene ID 50485

UniProt ID Q9NZC9

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved