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16 –31 July 2013

ARVs and bone health: the role of NRTIs in second-line therapy HIV Treatment Bulletin, UK – 16 July 2013 Simon Collins, HIV i-Base The final clinical late-breaker oral presentation reported significantly less reduction in bone mineral density (BMD) after a year on an NRTI-sparing combination in a randomised study compared to standard NRTI-containing treatment. ...otherwise, references are to the Programme and Abstracts for the 7th IAS Conference on HIV Pathogenesis, Treatment and Prevention 30 June 3 July...

A 15-Year Jump in Life Expectancy for People With HIV AIDSmeds, USA – 16 July 2013 American and Canadian people whose HIV is treated with antiretrovirals (ARVs) enjoyed an increase in life expectancy of 15 years between the time periods of 2000 to 2002 and 2006 to 2007. ...2000 and 2007. The findings were presented at the 7th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (IAS

What Can We Look Forward to in HIV Cure Research? Investor Village, USA – 16 July 2013 http://www.thebodypro.com/content/72201/what-can-we-look-forward-to-in-hiv-cure- research.html Part Two of a Two-Part Conversation With Research Advocate Richard Jefferys By Nelson Vergel, B.S.Ch.E., M.B.A. From TheBodyPRO. ...being off treatment for eight and 15 weeks, according to data presented at IAS 2013.] There is also a big ongoing trial in the Cancer Trials...

IAS 2013: Many People Need Hepatitis B Treatment in the Gambia Topix, USA – 16 July 2013 About 8% of people tested through a community-based screening program in the Gambia have hepatitis B, and about 8% of these have advanced liver disease and meet European criteria for antiviral therapy, according to a report presented at the 7th International AIDS Society Conference on HIV IAS 2013: Many People Need Hepatitis B Treatment in the Gambia About 8% of people tested through a community-based screening program in the Gambia...

HIV Detectable in Semen of MSM Despite Suppression in Blood: First Longitudinal Study NATAP, USA – 16 July 2013 7th IAS Conference on HIV Pathogenesis, Treatment and Prevention, June 30-July 3, 2013, Mark Mascolini In the first study to track HIV shedding in semen over time in men who have sex with men (MSM) with sustained HIV suppression in blood, 7. ...Semen of MSM Despite Suppression in Blood: First Longitudinal Study 7th IAS Conference on HIV Pathogenesis, Treatment and Prevention, June 30-July...

IAS 2013: Kidney Problems Linked to Tenofovir Use, Improve with Switch to Abacavir Topix, USA – 17 July 2013 Indian people with HIV who took tenofovir had a higher rate of kidney impairment than westerners, according to a study presented at the 7th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention this month in Kuala Lumpur. IAS 2013: Kidney Problems Linked to Tenofovir Use, Improve with Switch to Abacavir Indian people with HIV who took tenofovir had a higher rate. New Global HIV Treatment Guidelines Aren't Just About Starting Early, Top Expert Warns TheBody.com, USA – 17 July 2013 "We can't focus entirely on public health at the expense of individuals," says Joel Gallant, M.D. ...interview with Fred Schaich of the International Foundation for Alternative Research in AIDS (IFARA) at IAS 2013, Gallant discusses what the newly...

IAS 2013: Kidney Problems Linked to Tenofovir Use, Improve with Switch to Abacavir Topix, USA – 17 July 2013 Indian people with HIV who took tenofovir had a higher rate of kidney impairment than westerners, according to a study presented at the 7th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention this month in Kuala Lumpur. IAS 2013: Kidney Problems Linked to Tenofovir Use, Improve with Switch to Abacavir Indian people with HIV who took tenofovir had a higher rate...

Stem Cell Transplant Patients Renew Excitement for HIV Cure Investor Village, USA – 17 July 2013 Medscape Medical News Conference News Stem Cell Transplant Patients Renew Excitement for HIV Cure Neil Canavan Jul 09, 2013 5 comments Print Email Editors' ...grabbing results, presented during a news conference here at the 7th International AIDS Society (IAS) Conference on HIV Pathogenesis, Treatment and...

Negative Gay Men Consider Viral Load Before Unprotected Sex POZ, USA – 17 July 2013 HIV-negative gay men are much less likely to engage in unprotected anal intercourse with an HIV- positive partner if they perceive him to have a detectable viral load, the National AIDS Treatment Advocacy Project reports. ...other HIV negative) and presented their findings at the 7thInternational AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (IAS...

Facing Sequestration, Senate Appropriates Funding for HIV EDGE New York City, USA – 18 July 2013 With sequestration cuts savaging federal funding for HIV prevention and care, the Senate Appropriations Committee on July 11 moved to pass legislation to keep the funding at 2013 levels, with an additional $51M for the Ryan White HIV/AIDS Program. ...HIV Prevention Research in a Challenging Environment" released at 7th IAS Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2013)

Making It Official: HIV Meds Have Improved Vastly AIDSmeds, USA – 18 July 2013 During the history of HIV, clinical trials of antiretrovirals (ARVs) have charted a steady, upward climb in efficacy, according to a large meta-analysis, MedPage Today reports. ...revolution. The investigators reported their findings at the 7th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention...

Low-cost condoms key to preventing AIDS worldwide Big News Network.com, Australia – 19 July 2013 -- An AIDS expert said at a conference in it is imperative to switch approaches to a public health perspective of prevention to stem the HIV spread. to a public health perspective," Tan told The Seventh International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention i

International AIDS Society – Press Clippings, 16-31 July 2013 2 IAS 2013: PrEP Appears Safe for Use in Conception, But May Not Be Necessary HIVandHepatitis.com, USA – 19 July 2013 HIV negative women who wish to become pregnant with their male HIV positive partner can be reassured that pre-exposure prophylaxis (PrEP) appears to be a safe option in terms of maternal and infant outcomes, according to data presented at the 7th International AIDS Society Conference on HIV IAS 2013: PrEP Appears Safe for Use in Conception, But May Not Be Necessary HIV negative women who wish to become pregnant with their male HIV.

Comment: Common sense needed in HIV fight Mail & Guardian Online, South Africa – 19 July 2013 A recent international Aids conference lacked input from those living with the HI virus. Comment: Common sense needed in HIV fight A recent international Aids conference lacked input from those living with the HI virus. The HIV Pathogenesis,

Less Education Linked to Later HIV Diagnosis, Higher Mortality in 13-Cohort European Study NATAP, USA – 19 July 2013 7th IAS Conference on HIV Pathogenesis, Treatment and Prevention, June 30-July 3, 2013, Kuala Lumpur Mark Mascolini People with less education got diagnosed with HIV infection later in the course of their illness and, largely as a result, started antiretroviral therapy (ART) later than did people ...Later HIV Diagnosis, Higher Mortality in 13-Cohort European Study 7th IAS Conference on HIV Pathogenesis, Treatment and Prevention, June 30-July...

HIV Cure Research: Then, Now and in the Future TheBody.com, USA – 19 July 2013 "The development of antiretroviral drugs, which were designed to inhibit virus from replicating, was a spectacular success. to discuss some of the HIV cure research highlights coming out of IAS 2013. The interview includes updates on the Mississippi baby who was cured...

Statins Take Bite Out of Cancer Risk in People With HIV POZ, USA – 19 July 2013 Taking statins nearly cuts in half the risk of developing cancer among people with HIV, MedPage Today reports. ...cholesterol-lowering drugs. They presented their findings at the 7th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention...

MSM HIV Sex/Substance Abuse Risk Intervention in South Florida: Single 1-on-1 Session Works as Well as 4 Group Sessions in Trimming MSM Risk Behavior NATAP,, USA – 20 July 2013 from jules: not addressed in this study is the risk for HCV transmission. ...sharing for recreational drug use & accompanying risky sexual behavior. 7th IAS Conference on HIV Pathogenesis, Treatment and Prevention, June 30-July...

Switching HIV Clinics Linked to Higher Mortality in Large Austrian Study NATAP, USA – 20 July 2013 7th IAS Conference on HIV Pathogenesis, Treatment and Prevention, June 30-July 3, 2013, Kuala Lumpur Mark Mascolini People who switched from one HIV clinic to another had an 86% higher death rate than people who stayed at the same clinic, according to results of a 5-year 4891-person study in

International AIDS Society – Press Clippings, 16-31 July 2013 3 Switching HIV Clinics Linked to Higher Mortality in Large Austrian Study 7th IAS Conference on HIV Pathogenesis, Treatment and Prevention, June 30-July...

ART Linked to Lower Sexual (But Not Drug-Injecting) Risk Behavior in Meta-Analysis NATAP,, USA – 20 July 2013 7th IAS Conference on HIV Pathogenesis, Treatment and Prevention, June 30-July 3, 2013, Kuala Lumpur Mark Mascolini People taking antiretroviral therapy (ART) had lower odds of unprotected sex and new sexually transmitted infections (STIs) than did people not taking ART, according to results of a ...Sexual (But Not Drug-Injecting) Risk Behavior in Meta-Analysis 7th IAS Conference on HIV Pathogenesis, Treatment and Prevention, June 30-July 3,

Number of ART Regimens But Not Time on ART or Tenofovir Tied to Low Bone Density NATAP, USA – 20 July 2013 7th IAS Conference on HIV Pathogenesis, Treatment and Prevention, June 30-July 3, 2013, Kuala Lumpur from jules: the SECOND-LINE Study presented at IAS on bone loss found that when switching to their second regimen after failing the first bone loss worsened. ...Regimens But Not Time on ART or Tenofovir Tied to Low Bone Density 7th IAS Conference on HIV Pathogenesis, Treatment and Prevention, June 30-July 3,

In Utero HAART Exposure Associated with Decreased Growth among HIV-Exposed Uninfected Breast Fed Infants in Botswana NATAP, USA – 20 July 2013 Reported by Jules Levin IAS 2013 June 30-July 3 Kuala Lumpur, Malaysia Authors: Kathleen Powis1,2,3, Laura Smeaton2, Wafaie Fawzi2, Anthony Ogwu3, Esther Machakaire3, Sajini Souda3, Kathleen Wirth2, Joseph Makhema3, Shahin Lockman2,3,4, Max Essex2,3, Roger Shapiro2,3,5 1Massachusetts General ...HIV-Exposed Uninfected Breast Fed Infants in Botswana Reported by Jules Levin IAS 2013 June 30- July 3 Kuala Lumpur, Malaysia Authors: Kathleen...

IAS 2013: Darunavir/Ritonavir Is Safe and Effective for Younger Children with HIV Topix, USA – 21 July 2013 Over 80% of treatment-experienced children with HIV aged 3 to 6 years who received ritonavir- boosted darunavir with an optimized background regimen achieved virological suppression by 48 weeks, with a favorable safety profile, according to a report at the 7th International AIDS Society Conference IAS 2013: Darunavir/Ritonavir Is Safe and Effective for Younger Children with HIV Over 80% of treatment-experienced children with HIV aged 3

Stem Cell Transplantation for HIV: Do We Know Enough Yet? BioPortfolio, UK – 22 July 2013 Dr. Paul Sax considers what we know and don't know about the use of stem cell transplantation in eradicating HIV, as presented at IAS 2013. ...know and don't know about the use of stem cell transplantation in eradicating HIV, as presented at IAS 2013. Dr. Paul Sax considers what we know...

Eric Blue, 12-Year Old Boy with HIV and Blood Cancer Dies from Cell Transplant Complications; Risk-Factors Enlightens Experts International Business Times, Australia– 22 July 2013

International AIDS Society – Press Clippings, 16-31 July 2013 4 A 12-year old boy with HIV and leukaemia died after a historic cell transplant at the University of Amplatz Children's Hospital aimed to get the same result of three men cured of HIV and blood cancers. ...in the studies that are ongoing," Dr. Henrich said at the International AIDS Society conference at Kuala Lumpur, Malaysia. Eric Blue's Tragic...

What 's Sex Workers Want: Power, Not Rescue The Huffington Post - Blog, USA – 22 July 2013 Anu Mokal wasn't breaking the law when she was out walking with her friend last year, yet to the police, her very existence was criminal. ...workers." According to a 2012 study by the Journal of the International AIDS Society, published before the Supreme Court decision, groups have refused...

Number of regimens rather than cumulative exposure to antiretrovirals associated with lower bone mineral density in HIV-positive subjects NATAP, USA – 22 July 2013 Reported by Jules Levin IAS 2013 June 30-July 3 Kuala Lumpur, Malaysia AG Cotter1,2 CA Sabin,3 S Simelane,1 A Macken,1 B Rogers,1 E Kavanagh,2 1HIV Molecular Research Group, School of Medicine and Medical Science, University College , Dublin, Ireland, 2Mater Misericordiae University Hospital, ...with lower bone mineral density in HIV-positive subjects Reported by Jules Levin IAS 2013 June 30- July 3 Kuala Lumpur, Malaysia AG Cotter1,2

Quad Pill Measures Up to Two Other HIV Drug Regimens AIDSmeds, USA – 23 July 2013 Ninety-six week data from two randomized clinical trials show that the single-pill, once-daily antiretroviral therapy Stribild (elvitegravir/cobicistat/emtricitabine/tenofovir), also known as the “Quad” pill, is as effective as both Atripla (efavirenz, emtricitabine, tenofovir) and a Reyataz plus ...plus Truvada. They presented their findings at the 7th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (IAS...

Hep B or C Coinfection Spells Worse Response to HIV Meds AIDSmeds, USA – 23 July 2013 People with HIV who are coinfected with either hepatitis B or C virus (HBV/HCV) experience diminished response to antiretroviral (ARV) treatment for HIV and have a greater risk of death when compared with those monoinfected with HIV, Healio.com reports. ...C. The researchers presented their findings at the 7th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (IAS...

IAS 2013: Meta-analysis Finds Early HIV Treatment Reduces Risk of AIDS and Death Topix, USA – 24 July 2013 A meta-analysis of more than 30 studies found that starting antiretroviral therapy with a CD4 T-cell count above 350 cell/mm3 was associated with a lower risk of progression to AIDS or death, according to a poster presented at the 7th International AIDS Society Conference on HIV Pathogenesis, IAS 2013: Meta-analysis Finds Early HIV Treatment Reduces Risk of AIDS and Death A meta-analysis of more than 30 studies found that starting...

IAS 2013: HIV/HCV Coinfected Children in Europe Have Poor Hepatitis C Treatment Outcomes HIVandHepatitis.com, USA - 24 July 2013

International AIDS Society – Press Clippings, 16-31 July 2013 5 TEXT Subscribe To Our Newsletter Sign up for our free twice-weekly e-newsletter CONTINUING MEDICAL EDUCATION Library of CME Programs More CME Programs... IAS 2013: HIV/HCV Coinfected Children in Europe Have Poor Hepatitis C Treatment Outcomes TEXT Subscribe To Our Newsletter Sign up for our free...

Barriers to PMTCT in Sub-Saharan Africa Aids Alliance, UK – 24 July 2013 Our latest peer reviewed publication addressing the uptake of anti-retroviral drugs for prevention of mother-to-child transmission of HIV in sub-Saharan Africa, has just been published in the Journal of the International AIDS Society. ...sub-Saharan Africa, has just been published in the Journal of the International AIDS Society. The article set out to investigate and synthesize reasons...

Murdered gay rights/HIV advocate and journalist documented deadly conditions Science Speaks: HIV & TB News, USA – 24 July 2013 At the end of a Senate briefing last week offering updates on science’s strides against HIV and AIDS worldwide, Dr. Chris Beyrer of John Hopkins University, and president-elect of the International AIDS Society offered a sobering counterpoint to the news of encouraging advances. ...of John Hopkins University, and president-elect of the International AIDS Society offered a sobering counterpoint to the news of encouraging...

Transmitted NNRTI Resistance Rate Climbing in US But Flat in Big European Countries NATAP, USA – 24 July 2013 7th IAS Conference on HIV Pathogenesis, Treatment and Prevention, June 30-July 3, 2013, Kuala Lumpur Mark Mascolini Prevalence of transmitted nonnucleoside (NNRTI) resistance mutations rose in the and small European countries through recent years, according to an 84-study ...Resistance Rate Climbing in US But Flat in Big European Countries 7th IAS Conference on HIV Pathogenesis, Treatment and Prevention, June 30-July...

Zambia: Catching up with Male Circumcision Advocate Chief Mumena All Africa.com, USA - 24 July 2013 As the influential leader of 's Kaonde people, Chief Jonathan Eshiloni Mumena's decision to undergo male circumcision was nothing short of a public health practitioner's dream. to act. AllAfrica first spoke to Chief Mumena last July at the International Aids Society Conference in Washington, DC. We checked in with him...

New HIV diagnoses in London's gay men continue to soar TheLancet.com, UK – 25 July 2013 HIV infections in London's men who have sex with men have risen sharply from 2011 to 2012, according to the latest government statistics. ...Trust, UK, and colleagues recently presented a study at the International AIDS Society meeting in Kuala Lumpur, Malaysia, showing that around...

5th International Workshop on HIV Pediatrics, 28-29 June 2013, Kuala Lumpur HIV Treatment Bulletin, UK – 25 July 2013 The International Workshop on HIV Pediatrics is into its fifth year now an annual fixture, held immediately before the IAS conference. ...fifth year now an annual fixture, held immediately before the IAS conference. The International Workshop on HIV Pediatrics is into its fifth...

International AIDS Society – Press Clippings, 16-31 July 2013 6 Non-standard combinations: NRTI-sparing combinations HIV Treatment Bulletin, UK – 25 July 2013 Simon Collins, HIV i-Base A number of small studies presented results at IAS 2013 on combinations that are not widely used or recommended in first or second line therapy. ...Collins, HIV i-Base A number of small studies presented results at IAS 2013 on combinations that are not widely used or recommended in first or second...

Argos Clinical Trial Targets HIV Viral Load for Eradication :: EDGE San Francisco EDGE San Francisco, USA - 26 July 2013 After years of clinical trials, Argos Therapeutics Inc., a biopharmaceutical company, has unveiled AGS-004, a new personalized immunotherapy for HIV patients that could prove to be the future of HIV eradication research, without requiring them to stop their existing antiretroviral therapy. ...Symposium on June 29-30, which precedes the 7th Annual International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention in Kuala...

Opinion: New WHO Guidelines on HIV Treatment Offer Opportunities, Challenges TheBody.com, USA - 26 July 2013 Writing in a Lancet opinion piece, Kenneth Mayer of Harvard Medical School and Chris Beyrer, director of the Johns Hopkins Fogarty AIDS International Training and Research Program and Center for Public Health & Human Rights, discuss the opportunities and challenges presented by the WHO's revised ...antiretroviral therapy (HAART)," released earlier this month at the International AIDS Society (IAS) conference. Mayer and Beyrer discuss the details...

A small boy with a big message IOL - Independent Online, South Africa – 27 July 2013 - A quiet kid who couldn’t tell a joke without messing up the punchline – that’s how Gail Johnson likes to remember Nkosi, her 12-year-old who became one of the Aids struggle’s most powerful icons. Still, he got on stage in July that year to address the 13th International Aids Conference in Durban. His speech would become known as his Miracle...

Life Expectancy for People Living With HIV Increases by 15 Years TheBody.com, USA - 29 July 2013 A person living with HIV who is on treatment in the U.S. or can expect to live almost a normal lifespan, according to a study presented at IAS 2013. ...can expect to live almost a normal lifespan, according to a study presented at IAS 2013. A person living with HIV who is on treatment in the U.S.

Experts cautious of new HIV treatment guidelines Soweto - Show Me, South Africa- 29 July 2013 source: health24 A leading South African AIDS expert has cautioned that new guidelines on HIV treatment may be a distraction to the country’s ongoing treatment efforts. ...be fixed first. The new WHO recommendations, issued at the recent 7th IAS Conference in Malaysia, pushes for people with a CD4 count of 500 or...

South Africa: Statement By the Office of the Minister of Tourism, Mr Marthinus Van Schalkwyk, On the Occasion of the Annual South African Association for the Conference Industry (saaci) Event Hosted At the Boardwalk Convention Centre, Port Elizabeth South African Government Information, South Africa - 29 July 2013 All Africa.com, USA - 29 July 2013 I am delighted that the Nelson Mandela Bay Municipality now has a convention centre of its own.

International AIDS Society – Press Clippings, 16-31 July 2013 7 ...000 delegates to the country. One of the biggest will be the 21st International Aids Conference, which is to be held in 2016 in Durban. These...

Business is booming for SA tourism IOL - Independent Online, South Africa – 30 July 2013 Johannesburg - Business events are a key contributor to tourism growth, Tourism Minister Marthinus van Schalkwyk said. ...200 000 delegates to the country. Among these events, was the International Aids Conference, which would be held in Durban in 2016, Van Schalkwyk...

Business boosts tourism Business - iafrica.com, South Africa – 30 July 2013 The business events industry has played an important role in the growth of the tourism sector, according to Tourism Minister Marthinus van Schalkwyk. ...secure 88 events for the period from 2013 to 2017, including the International Aids Conference, which will be held in Durban in 2016. Van Schalkwyk...

Steps Toward HIV Cure ChinAfrica, China – 30 July 2013 Two more HIV-infected patients appear to be virus-free after bone-marrow ...virus-free after bone-marrow transplants This year's International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention, held...

Cure Strategies: "Viral and Immune-Targeted Interventions: Hit Me with Your Best Shot" - Oral Session at IAS 2013 Kulala Lumpur June 30-July 3 NATAP, USA – 31 July 2013 Reported by Jules Levin from Jules: there were 4 oral slide presentations in this session on cure strategies. presentations/program abstracts: Destruction of the residual active HIV-1 reservoir by Env-specific immunotoxin Presented by J. Victor Garcia (United States). ...Immune-Targeted Interventions: Hit Me with Your Best Shot" - Oral Session at IAS 2013 Kulala Lumpur June 30-July 3 Reported by Jules Levin from Jules:

HPV Vaccine Could Reduce Anal Cancer Rates in Older Gay Men ILGA, USA – 31 July 2013 Human papillomavirus (HPV) vaccines, given to older gay men, could prevent the transmission of strains of the virus that lead to anal cancer, aidsmap reports. ...development by Merck. They presented their findings at the 7thInternational AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (IAS... amfAR Funds $1.4M in Grants Toward HIV Eradication EDGE on the Net, USA – 31 July 2013 As part of its mission to accelerate promising research focused on finding a cure for HIV/AIDS on July 17, amfAR, The Foundation for AIDS Research, announced a new round of grants through its amfAR Research Consortium on HIV Eradication (ARCHE) program. HIV." Henrich presented preliminary findings on these patients at the International AIDS Conference last July. With support from amfAR, he conducted...

Pappas ‘steps down’ as head of DC AIDS office Washington Blade, USA – 31 July 2013

International AIDS Society – Press Clippings, 16-31 July 2013 8 Gay physician and AIDS specialist Gregory Pappas released a statement Tuesday night saying he was “stepping down” as head of the D.C. Department of Health’s HIV/AIDS, Hepatitis, STD and Tuberculosis Administration (HAHSTA). ...the once in a life time opportunity to represent the city at the 2012 International AIDS Society Meeting, which was held in D.C. He discusses..

Pappas Leaves DC HAHSTA Examiner.com - Washington DC, USA – 31 July 2013 Dr. Gregory Pappas was released yesterday from his position as Senior Deputy Director of the DC Department of Health's HIV/AIDS, Hepatitis, STD, and TB Administration (HAHSTA). ...is a long time DC resident and presided over HAHSTA during the 2012 International AIDS Conference last July. Prior to joining DC DOH, Dr. Pappas...

Report From The International AIDS Society's Conference PrideSource, USA – 31 July 2013 MALAYSIA -The 7th International AIDS Society's (IAS) Conference on HIV Pathogenesis, Treatment and Prevention ended July 1 after five days of intense presentations and discussions. Report From The International AIDS Society's Conference MALAYSIA -The 7th International AIDS Society's (IAS) Conference on HIV Pathogenesis,

International AIDS Society – Press Clippings, 16-31 July 2013 9