CURRICULUM VITAE

PERSONAL DATA

Name: Antonio Rodríguez-Moreno DNI: 34034496Q Born 30/11/1968 Sex: Male

Home Address: Calle Cerro del Marchal nº 6 41089 Montequinto (Dos Hermanas), Sevilla, Spain.

University address: Universidad Pablo de Olavide. Edificio 21. Ctra de utrera, Km 1. 41013. , Spain.

Tel: 954977393/ Mobile: 645848275 E-mail: [email protected]

EDUCATION

1992: Agricultural Engineer. 1995: Bachelor in Biological Sciences. University of Seville. 1998. Master in Neurosciences, Autonomous University of . 2000: Doctor in Biological Sciences. Autonomous University of Madrid and Institute Cajal (CSIC). Honours.

Present position:

FULL PROFESSOR OF PHYSIOLOGY AND NEUROSCIENCE). Since December 2016. Organism: UNIVERSITY PABLO DE OLAVIDE Centre: FACULTY OF EXPERIMENTAL SCIENCES Department: PHYSIOLOGY, ANATOMY AND CELL BIOLOGY Address: UNIVERSITY PABLO DE OLAVIDE (EDIFICIO 21) CTRA. DE UTRERA KM 1 41013 SEVILLE

PREVIOUS POSITIONS.

-Postdoctoral Researcher. Andalusian Laboratory of Biology. Spanish Research Council. 2001-2002. -Postdoctoral Researcher. Department of Pharmacology, University College London, London (UK). Laboratory of Dr. Talvinder Sihra. 2002-2003 and 2005. -Postdoctoral researcher. Department of Physiology, Anatomy and Genetics. University of Oxford. Laboratory of Dr. Ole Paulsen. March 2006-August 2008. -Assistant Professor. University Pablo de Olavide. 2001-2004. -University Lecturer. University Pablo de Olavide, Seville. 2004-2009. -Associate Professor. University Pablo de Olavide. 2009-2016. -Royal Society International Fellow. University of Oxford, Oxford (UK). 2008. -McDonnell Network for Cognitive Neuroscience Fellow. University of Oxford (UK). April-July 2009. -Visiting scientist at University of Cambridge, Cambridge (UK). 02/2011-05/2011. 1 -Visiting Research Fellow at Harvard University (USA). June-September 2011. -Visiting Research Fellow at Harvard University (USA). June-September 2012. -International Beaufort Scholar at St Johns College, University of Cambridge (UK). April-June 2016. -Visiting Professor. University of Turin. 2020.

TEACHING EXPERIENCE.

-Assistant Professor, University Lecturer, Associate Professor and Full Professor in theoretical and practical courses: Cronobiology (2001-02, 2002-03), Neurotoxicology (2001-02, 2002-03), Animal Physiology (2003-04), Human Physiology (2004-05, 2005-06, 2006-07, 2007-08, 2008-09, 2009-10, 2010-11, 2011-12, 2012-13, 2013-14; 2014-2015; 2015-16; 2016-17; 2017-18; 2018-19; 2019-20, 2020-21). All at the University Pablo de Olavide, Seville, Spain

-Professor at the Doctorate Program “Neuroscience and Behavioral Biology” (2001-02, 2004-05, 2005-06, 2006-07, 2007-08, 2008-09, 2009-10, 2010-11, 2011-12, 2012- 13, 2013-14; 2014-15, 2015-16; 2016-17; 2017-18; 2018-19). University Pablo de Olavide, Seville, Spain.

-Tutorial Teaching at University of Oxford (2008). Physiology and Neuroscience.

-Professor of the International University Centre of the University Pablo de Olavide. Teaching in English to students from USA universities. 2011, 2012, 2013, 2014.

-Director and Professor of Master Program in Neuroscience and Behavioral Biology. University Pablo de Olavide. Professor: From 2001 to 2018. Director: 2018.

-Director and Professor of Master Program in Fundamental and Translational Neuroscience, University Pablo de Olavide, Sevilla. Since 2018.

PARTICIPATION IN GRANTED PROJECTS.

Spanish and European agencies:

-1995-1996. “Structure and function of glutamate receptors of the kainate type”. 40.000 €.

-1995-1997. “Structure and function of glutamate receptors of the kainate type”. 80.000 €.

-1997-2000. “Structure and function of glutamate receptors of the kainate type”. 65.000 €.

-1999-2000. “Physiopathology of the Epilepsy: kainate receptors involved in GABA release”. 50.000 €.

-2000-2001. “Structure and function of glutamate receptors of the kainate type”. 100.000 €.

-2000-2002. BIOTECH. “Restitution of septo-hippocampal function in a Alzheimer disease model”. 350.000 €.

-1997-2004. Laboratory of Neuroscience. 98.000 €.

-2002-2004. “Experimental design for the in vivo study of motor learning and memory capabilities of wild and transgenic mice with Alzheimer-like deficits”. Aventis 2 Pharma Recherche. 300.000 €

-2002-2005. “Functional states and associative learning in mammals”. 353.150 €

-2003-2005. “Experimental design for the in vivo study of motor learning, memory and behavioural capabilities of wild and transgenic mice”. Aventis Pharma Recherche. 300.000 €.

-2006-2007. “Physiology of glutamate and nicotinic receptors”. 7.000 €. PI: A. Rodríguez- Moreno.

-2006-2008. “Physiological basis of learning and memory”. European Union. 165.000 €. PI: A. Rodríguez-Moreno.

-2006-2009. “Functions of kainate receptors in the hippocampus”. Grant from the Spanish Education and Research Ministry. Reference: BFU2006-14155/BFI. 87.120 €. PI: A. Rodríguez-Moreno.

-2006-2010. Participation in RETICS network in Biomedicine and Health Area. 163.200 €

-2007-2011. “Study of LTP in freely moving mice”. Andalucian Government. 400.000 €.

-2009-2011.“Setup for special electrophysiology”. Andalusian Government. 134.120 €. PI: A. Rodríguez-Moreno.

-2010-2012. “Role of kainate receptors in epilepsy”. Rodríguez-Pascual Foundation. 15.000 € PI: A. Rodríguez-Moreno.

-2009-2012. “Cellular mechanisms of spike timing-dependent plasticity”. Spanish Ministry for Science and Innovation. 139.150 €. PI: A. Rodríguez-Moreno.

-2012-2015. “Mechanisms of brain plasticity”. Andalusian Governmet. 275.631 €. Including money to hire 1 postdoc and 1 technician. PI: A. Rodríguez-Moreno.

-2012-2013. “Kainate receptors and epilepsy”. Foundation Rodríguez-Pascual. PI: A. Rodríguez-Moreno.

-2013-2015. “Cellular mechanisms of synaptic plasticity. How to manipulate plasticity?. Ministry of Economy and Comp. 152.100 €. PI: A. Rodríguez-Moreno.

2013-2015. Presynaptic NMDA receptors and plasticity. Royal Society. United Kingdom. Together with the University of Cambridge (UK). 12.000 £.

2013-2016. Two-Photon Microscope and Physiology Setup. Ministry of Economy and Competitiveness. Infrastructure Grant. 1.200.000 €.

2016-2019. Synaptic Plasticity. Ministry of Economy and Competitiveness. 225.000 €.

2017-2021. CostAction 16210. Maximising the Impact of Research in Neurodevelopmental Disorders. European Commission H2020. 558.000 euros. PI: Adrian Harwood. Cardiff University. In Spain: Antonio Rodríguez-Moreno. 3

2020-2022. Mechanism and functions of synaptic plasticity. Spanish Goverrnment. 177.000 €. PI: A. Rodríguez-Moreno.

Industry and transference of knowledge:

-2001-2003. Collaboration with AVENTIS-PHARMA. “Experimental design for the in vivo study of motor learning and memory capabilities transgenic mice with Alzheimer’s like deficits”. 100.000 €.

-2003-2005. Collaboration with AVENTIS-PHARMA. “Experimental design for the in vivo study of motor learning, memory and behavioural capabilities of wild and transgenic mice”. 300.000 €.

CONFERENCES AND SEMINARS BY INVITATION (selected).

-Invited Speaker, Autonomous University of Madrid, Madrid, Spain. 1997.

-Invited Speaker, University of Seville. Seville, Spain. 1998.

-Local Speaker, Institute Cajal, Spanish Research Council, Madrid, Spain.1998

-Plenary Conference as winner of the prize “Innogenetics Therapeutics and Diagnostic”. XXII Congress of the Spanish Society of Biochemistry and Molecular Biology. Pamplona, Spain. 1999.

-Invited Speaker, Autonomous University of Madrid, Madrid, Spain. 1999.

-Invited Speaker, University Pablo de Olavide, Seville, Spain. 2000.

-Invited speaker, University Pablo de Olavide, Seville, Spain. 2001.

-Invited Speaker, University College London, London, United Kingdom. 2002.

-Invited speaker to a Conference at Institute for Neurosciences. University of Granada, Granada, Spain. 2003.

-Invited Speaker, Faculty of Medicine, University of Seville, Seville, Spain 2004.

-Invited Speaker, Faculty of Biology, University of Malaga, Málaga, Spain 2007.

-Invited Speaker, Faculty of Medicine, University of Lérida, Lérida, Spain 2008.

-Invited Speaker, Faculty of Medicine, University of , Valencia, Spain. 2009.

-Invited Speaker, Faculty of Medicine, University of Málaga, Málaga, Spain. 2009.

-Chair and speaker. Symposium at the Spanish Society for Neuroscience, Tarragona, Spain. 2009.

-Invited Speaker. University of Zurich, Zurich, Switzerland. 2009. 4

-Invited Speaker, Institute Cajal, Madrid, Spain. 2011.

-Co-Chair and Speaker. FENS Regional Meeting. Prague. 2013.

-Invited Speaker. Centre for Biomedicine (CIMA). University of Navarra. November 2013.

-Invited speaker. Autonomous University of Madrid. January 2014.

-Invited speaker. Institute of Nervous System Diseases. University of Castilla-La Mancha. May 2014.

-Invited speaker. Institute Cajal. Spanish research Council. June 2014.

-Invited speaker. Universidad de Málaga. Octubre 2015.

-Chair and speaker Symposium: New insights into synaptic plasticity. FALAN Meeting. Buenos Aires (Argentina). 2016.

-Speaker International Symposium. Spanish Society of Neuroscience (SENC). Alicante (Spain). 2017.

-Chair Symposium FENS Meeting 2018. Berlin, 2018.

-Speaker in Symposium. Spanish Society of Biochemistry and Molecular Biology (SEBBM). Santander. 2018.

-Speaker in Symposium. International Society of Neurochemistry (ISN). Montreal. Canada, 2019.

-Speaker in Symposium. Israel Society For Neuroscience. Israel. 2021.

HONOURS AND AWARDS.

-1995-1996. PhD. Fellowship from the Spanish National Institute of Health.

-1996-2000. PhD. Fellowship from the Spanish Education and Science Ministry.

-2001-2002. Postdoctoral Fellowship from the Spanish Science and Technology Ministry.

-1999. Young Scientist Award from The Spanish Society for Molecular Biology and Biochemistry.

-2000. Royal Academy for Doctors Award (Spanish Academy) to the most outstanding PhD thesis in Biochemistry or Physiology during the year 2000 in Spain.

-2001. Extraordinary Doctorate Award in Biological Sciences. University Autonomous of Madrid.

-2002. Neuroscience Award for Young Scientists. Institute for Neurosciences “F. Olóriz” (Granada, Spain). To the paper “Two populations of kainate receptors with separate signaling mechanisms in hippocampal interneurons” Proc. Natl. Acad. Sci. USA 98(3):1293-1298 (2000). 5

-2002. EMBO Short-Term Fellowship. Talvinder Sihra´s lab. Department of Pharmacology, University College London, London, UK.

-2002-03. Human Frontier Short-Term Fellowship. Talvinder Sihra´s lab. Department of Pharmacology, University College London, London, UK.

-2005. FEBS Short-Term Fellowship. Talvinder Sihra´s lab. Department of Pharmacology, University College London, London, UK.

-2006-2008. Marie Curie Intraeuropean Fellowship. Ole Paulsen´s Lab. Department of Physiology, Anatomy and Genetics. University of Oxford, Oxford, UK.

-2008. Royal Society International Fellow. University of Oxford, Oxford (UK). 2008.

-2009. McDonnell Network for Cognitive Neuroscience Fellow. University of Oxford (UK). April-July 2009.

-2011. Complutense Fellowship. Harvard University. USA.

-2012. Complutense Fellowship. Harvard University. USA.

-2016. International Beaufort Scholar at St Johns College, University of Cambridge (UK). April-June 2016

-2020. Visiting Professor University of Turin, Turin ().

OTHERS.

1999-Present. Member of the Spanish Society for Biochemistry and Molecular Biology (SEBBM). 1999-Present. Member of Federation of European Biochemistry Societies (FEBS). 2001-Present. Member of the Spanish Society for Neuroscience (SENC). 2001-Present. Member of Federation of European Neurosciences Societies (FENS). 2004-Present. Member of the Spanish Society of Physiological Sciences (SECF). 2007-Present. Member of the Society for Neuroscience (SFN). 2017-Present. Member of the European Society for Neurochemistry (ESN) 2013-Present. Member of the international Society of Neurochemistry (ISN).

Languages.

Spanish: native speaker, English: fluent, writing and speaking, French: fluent, writing and speaking.

ADMINISTRATIVE AND CHAIRING ACADEMIC POSTS IN THE UNIVERSITY PABLO DE OLAVIDE:

-Member of the research Commission of the Department of Physiology, Anatomy and Cell Biology.

6 -Member of the research Commission of the University Pablo de Olavide.

-Elected Member of the Academic board (governing body) of the University Pablo de Olavide.

-Director of the Master Program in Fundamental and Translational Neuroscience of the university Pablo de Olavide.

-Chair in Neuroscience

INTERNATIONAL EXPERIENCE

P = postdoctoral, I = invited, O = other

1. Centre: University College London City: London Country: United Kingdom Years: 2002-2003 Duration: 7 months, from 1/08/2002 to 28/02/2003 Field: Cellular physiology of kainate receptors P

2. Centre: University College London City: London Country: United Kingdom Year: 2005 Duration: 3 months, from 31/07/2005 to 31/10/2005 Field: Cellular physiology of kainate receptors P

3. Centre: University of Oxford City: Oxford Country: United Kingdom Years: 2006, 2007 y 2008 Duration: 2 years, from 11/03/2006 to 10/03/2008 Tema: Spike timing-dependent plasticity physiology at somatosensory cortex. Clave: P

4. Centre: University of Oxford City: Oxford Country: United Kingdom Years: 2008 Duration: 2 months, from 16/06/2008 to 16/08/2008 Tema: Spike timing-dependent plasticity physiology at somatosensory cortex. Clave: Senior Researcher

5. Centre: University of Oxford City: Oxford Country: United Kingdom Years: 2009 Duration: 3 months, from 27/04/2009 to 27/07/2009 Tema: Spike timing-dependent plasticity physiology at somatosensory cortex. Clave: Senior Researcher. 7

6. Centre: University of Cambridge City: Cambridge Country: United Kingdom Year: 2011 Duration: 3 months and 8 days, from 11/02/2011 to 18/05/2011 Field: Plasticity at somatosensory cortex O, Visiting Researcher.

7. Centre: Harvard University City: Cambridge Country: United States Year: 2011 Duration: 3 months 06/2011 to 09/2011 Field: Plasticity at somatosensory cortex O, Visiting Researcher.

8. Centre: Harvard University City: Cambridge Country: United States Year: 2012 Duration: 3 months 06/2012 to 09/2012 Field: Plasticity at somatosensory cortex O, Visiting Researcher.

Memberships to Editorial Boards of International Journals:

-Associate Editor of “Frontiers in Pharmacology”. -Member of the Editorial Board of “Scientific Reports” -Member of the Editorial Board of “Signal transduction Insights”.

OTHERS.

-2003-Present. Academic member of the Royal Academy of Medicine and Surgery of Granada.

-Ad hoc referee of the Journals:

-Science -Nature Neuroscience -Neuron -Nature Communications -British Journal of Pharmacology -European Journal of Neuroscience -Neuroscience -Neuroscience Letters -Journal of Physiology -Journal of Neuroscience -Developmental Neurobiology, ETC.

-Referee of National (MICIIN, Community of Castilla-La Mancha, Community of Castilla- León, Community of Madrid) and International agencies: Wellcome Trust, MRC, BBSRC (UK) 8 CONACYT (México). European Commission Human Brain Project European Science Foundation

Supervised PhD thesis:

1. Title: Papel de los receptores de kainato en la regulación de la liberación de glutamato en el hipocampo de ratón (Role of kainate receptors in the modulation of glutamate release in the Mouse hippocampus). Student: José Vicente Negrete Díaz University: Pablo de Olavide de Sevilla Faculty: Facultad de Ciencias Experimentales Date: March 2009.

2. Title: Role of Spike timing-dependent plasticity in early mammalian cortical development Atudent: Abhishek Banerjee University: University of Oxford (Co-supervised with Prof. Ole Paulsen) Faculty: Department of Physiology, Anatomy and Genetics. University of Oxford. Date: April 2010.

3. Title: Papel de los receptores de glutamato de tipo kainato y metabotrópicos del grupo II en la sinapsis fibra musgosa-CA3 del hipocampo de ratón (Role of kainate type and group II metabotropic glutamate receptors at mossy fiber-CA3 synapses). Student: Miriam Carrión Reinoso University: Pablo de Olavide de Sevilla Faculty: Facultad de Ciencias Experimentales Date: October 2011.

4. Title: Caracterización neuropsicológica y programa de intervención cognitivo en una paciente de 7 años con diagnóstico de monosomía 1p36 (Neuropsychological characterization and cognitve intervention program in a 7 years old patient with diagnosed with 1p36 monosomy syndrome). Student: Sabina A. Bello Rodríguez University: Pablo de Olavide de Sevilla Faculty: Facultad de Ciencias Experimentales Date: May 2012.

5. Title: Funciones de los receptores de glutamato de tipo kainato en la sinapsis fibra- musgosa-CA3 de hipocampo (Functions of kainate type glutamate receptors at hippocampal mossy-fibre-CA3 synapses). Student: Yuniesky Andrade Talavera University: Pablo de Olavide de Sevilla Faculty: Facultad de Ciencias Experimentales Date: September 2012

6. Title: Santiago Ramón y Cajal e Ivan Petrovic Pavlov. Comparación de su vida y obra (Santigago Ramón y Cajal and Ivan Petrovic Pavlov. Comparison of their lives and work). Student: Jairo Alonso Rozo Castillo University: Pablo de Olavide de Sevilla 9 Faculty: Facultad de Ciencias Experimentales Date: September 2014.

7. Title: Cellular mechanisms of spike timing-dependent plasticity. Student: Paloma duque-Feria University: Pablo de Olavide de Sevilla Faculty: Facultad de Ciencias Experimentales Date: December 2015

8. Title: Mecanismos celulares y moleculares involucrados en los cambios de plasticidad sináptica que ocurren durante el desarrollo juvenil en el hipocampo de ratón (Cellular and Molecular mechanisms involved in the changes in synaptic plasticity during development in juvenile hippocampus of mice). Student: José Prius-Mengual University: Pablo de Olavide de Sevilla Faculty: Facultad de Ciencias Experimentales Date: 2019.

9. Title: Role of kainate receptors in the modulation of glutamate release in the cerebellum. Student: Pilar Losada Ruiz University: Pablo de Olavide de Sevilla Faculty: Facultad de Ciencias Experimentales Date: 2021.

Participation in national and international meetings

More than 200 presentations including, Poster, Oral Presentations, Speaker in Symposium and Chair in Symposia.

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