© 2000-2013 Ingenuity Systems, Inc. All rights reserved. Category Functions Annotation p-Value Cellular Function and Maintenance organization of cells 1.91E-04 Cellular Growth and Proliferation cytostasis of breast cancer cell lines 6.73E-04 Dermatological Diseases and Conditions psoriasis 7.74E-04 Cellular Growth and Proliferation contact growth inhibition of colon cancer8.47E-04 cell lines Cell Cycle contact growth inhibition of colon cancer8.47E-04 cell lines Cell-To-Cell Signaling and Interaction contact growth inhibition of colon cancer8.47E-04 cell lines Cellular Function and Maintenance formation of tight junctions 8.47E-04 Cell-To-Cell Signaling and Interaction formation of tight junctions 8.47E-04 Cellular Assembly and Organization formation of tight junctions 8.47E-04 Tissue Development formation of tight junctions 8.47E-04 Cancer ductal carcinoma in situ 1.03E-03 Cellular Function and Maintenance assembly of intercellular junctions 1.24E-03 Cell-To-Cell Signaling and Interaction assembly of intercellular junctions 1.24E-03 Cellular Assembly and Organization assembly of intercellular junctions 1.24E-03 Tissue Development assembly of intercellular junctions 1.24E-03 Cellular Assembly and Organization formation of plasma membrane 1.39E-03 Cell-To-Cell Signaling and Interaction adhesion of breast cell lines 1.46E-03 Tissue Development adhesion of breast cell lines 1.46E-03 Dermatological Diseases and Conditions plaque psoriasis 1.61E-03 Cell Cycle mitosis of breast cancer cell lines 1.69E-03 Cancer head and neck squamous cell carcinoma2.14E-03 Cellular Growth and Proliferation contact growth inhibition of tumor cell lines2.25E-03 Cell Cycle contact growth inhibition of tumor cell lines2.25E-03 Cell-To-Cell Signaling and Interaction contact growth inhibition of tumor cell lines2.25E-03 Developmental Disorder congenital anomaly of limb 2.36E-03 Skeletal and Muscular Disorders congenital anomaly of limb 2.36E-03 Cellular Growth and Proliferation cytostasis of tumor cell lines 2.53E-03 Cellular Growth and Proliferation proliferation of activated T lymphocytes2.82E-03 Cellular Development proliferation of activated T lymphocytes2.82E-03 Hematological System Development and Function proliferation of activated T lymphocytes2.82E-03 Cellular Movement invasion of prostate cancer cell lines 2.84E-03 Cellular Growth and Proliferation contact growth inhibition of breast cancer3.14E-03 cell lines Cell Cycle contact growth inhibition of breast cancer3.14E-03 cell lines Cell-To-Cell Signaling and Interaction contact growth inhibition of breast cancer3.14E-03 cell lines Auditory Disease nonsyndromic hearing impairment 3.14E-03 Hereditary Disorder nonsyndromic hearing impairment 3.14E-03 Neurological Disease nonsyndromic hearing impairment 3.14E-03 Auditory Disease sensorineural hearing loss 3.48E-03 Neurological Disease sensorineural hearing loss 3.48E-03 Gene Expression transactivation 4.21E-03 Dermatological Diseases and Conditions Palmoplantar keratoderma with deafness4.42E-03 Auditory Disease Palmoplantar keratoderma with deafness4.42E-03 Hereditary Disorder Palmoplantar keratoderma with deafness4.42E-03 Neurological Disease Palmoplantar keratoderma with deafness4.42E-03 Organismal Injury and Abnormalities Palmoplantar keratoderma with deafness4.42E-03 Developmental Disorder Syndromic microphthalmia 3 4.42E-03 Hereditary Disorder Syndromic microphthalmia 3 4.42E-03 Ophthalmic Disease Syndromic microphthalmia 3 4.42E-03 Cell-To-Cell Signaling and Interaction activation of osteoblasts 4.42E-03 Connective Tissue Development and Function activation of osteoblasts 4.42E-03 Skeletal and Muscular System Development and Functionactivation of osteoblasts 4.42E-03 Cell-To-Cell Signaling and Interaction adhesion of chronic lymphocytic leukemia4.42E-03 cells Tissue Development adhesion of chronic lymphocytic leukemia4.42E-03 cells Cellular Compromise adhesion of chronic lymphocytic leukemia4.42E-03 cells Tumor Morphology adhesion of chronic lymphocytic leukemia4.42E-03 cells Cell-To-Cell Signaling and Interaction adhesion of corneal stroma cells 4.42E-03 Tissue Development adhesion of corneal stroma cells 4.42E-03 Tissue Development adhesion of embryoblast 4.42E-03 Embryonic Development adhesion of embryoblast 4.42E-03 Cell-To-Cell Signaling and Interaction adhesion of neural stem cells 4.42E-03 Tissue Development adhesion of neural stem cells 4.42E-03 Dermatological Diseases and Conditions aplasia cutis congenita 4.42E-03 Developmental Disorder aplasia cutis congenita 4.42E-03 Hereditary Disorder aplasia cutis congenita 4.42E-03 Organismal Injury and Abnormalities aplasia cutis congenita 4.42E-03 Cell Death and Survival apoptosis of squamous epithelial cells4.42E-03 Developmental Disorder arrhythmogenic right ventricular dysplasia4.42E-03 familial 11 Cardiovascular Disease arrhythmogenic right ventricular dysplasia4.42E-03 familial 11 Auditory Disease autosomal dominant deafness type 3A4.42E-03 Hereditary Disorder autosomal dominant deafness type 3A4.42E-03 Neurological Disease autosomal dominant deafness type 3A4.42E-03 Developmental Disorder autosomal dominant osteopetrosis type4.42E-03 1 Skeletal and Muscular Disorders autosomal dominant osteopetrosis type4.42E-03 1 Hereditary Disorder autosomal dominant osteopetrosis type4.42E-03 1 Connective Tissue Disorders autosomal dominant osteopetrosis type4.42E-03 1 Hereditary Disorder autosomal recessive familial exudative4.42E-03 vitreoretinopathy Ophthalmic Disease autosomal recessive familial exudative4.42E-03 vitreoretinopathy Lipid Metabolism biosynthesis of CDP-diacylglycerol 4.42E-03 Small Molecule Biochemistry biosynthesis of CDP-diacylglycerol 4.42E-03 Cellular Function and Maintenance cell saturation density of colon cancer 4.42E-03cell lines Cell-To-Cell Signaling and Interaction cell-cell contact of breast cancer cell lines4.42E-03 Tissue Development cell-cell contact of breast cancer cell lines4.42E-03 Cell-To-Cell Signaling and Interaction cell-cell contact of breast cell lines 4.42E-03 Tissue Development cell-cell contact of breast cell lines 4.42E-03 Cell-To-Cell Signaling and Interaction cell-cell contact of squamous carcinoma4.42E-03 cells Tissue Development cell-cell contact of squamous carcinoma4.42E-03 cells Cellular Movement chemotaxis of squamous cell carcinoma4.42E-03 cell lines Developmental Disorder clubfoot 4.42E-03 Skeletal and Muscular Disorders clubfoot 4.42E-03 Cell Cycle cytokinesis of breast cancer cell lines 4.42E-03 Cellular Movement cytokinesis of breast cancer cell lines 4.42E-03 Cell Cycle entry into S phase of skin cancer cell lines4.42E-03 Cell-To-Cell Signaling and Interaction extension of focal adhesions 4.42E-03 Cellular Assembly and Organization extension of focal adhesions 4.42E-03 Tissue Development extension of focal adhesions 4.42E-03 Cell Morphology extension of focal adhesions 4.42E-03 Hereditary Disorder fatal infantile multiorgan disease 4.42E-03 Developmental Disorder fg syndrome type 4 4.42E-03 Skeletal and Muscular Disorders fg syndrome type 4 4.42E-03 Cellular Growth and Proliferation generation of breast cell lines 4.42E-03 Tissue Development generation of breast cell lines 4.42E-03 Hereditary Disorder glycosylphosphatidylinositol deficiency4.42E-03 Hereditary Disorder heterocellular hereditary persistence of4.42E-03 fetal hemoglobin Hematological Disease heterocellular hereditary persistence of4.42E-03 fetal hemoglobin Embryonic Development hypodorsalization 4.42E-03 Dermatological Diseases and Conditions hystrix ichthyosis with deafness 4.42E-03 Developmental Disorder hystrix ichthyosis with deafness 4.42E-03 Hereditary Disorder hystrix ichthyosis with deafness 4.42E-03 Organismal Injury and Abnormalities hystrix ichthyosis with deafness 4.42E-03 Cancer invasion of squamous carcinoma cells4.42E-03 Cellular Movement invasion of squamous carcinoma cells4.42E-03 Tumor Morphology invasion of squamous carcinoma cells4.42E-03 Dermatological Diseases and Conditions keratitis ichthyosis and deafness syndrome4.42E-03 Developmental Disorder keratitis ichthyosis and deafness syndrome4.42E-03 Hereditary Disorder keratitis ichthyosis and deafness syndrome4.42E-03 Organismal Injury and Abnormalities keratitis ichthyosis and deafness syndrome4.42E-03 Dermatological Diseases and Conditions knuckle pads, deafness and leukonychia4.42E-03 syndrome Developmental Disorder knuckle pads, deafness and leukonychia4.42E-03 syndrome Skeletal and Muscular Disorders knuckle pads, deafness and leukonychia4.42E-03 syndrome Hereditary Disorder knuckle pads, deafness and leukonychia4.42E-03 syndrome Cancer mixed intestinal and diffuse adenocarcinoma-unclassifiable4.42E-03 Gastrointestinal Disease mixed intestinal and diffuse adenocarcinoma-unclassifiable4.42E-03 Auditory Disease nonsyndromic dominant deafness, DFNA284.42E-03 Hereditary Disorder nonsyndromic dominant deafness, DFNA284.42E-03 Neurological Disease nonsyndromic dominant deafness, DFNA284.42E-03 Auditory Disease nonsyndromic recessive deafness DFNB1A4.42E-03 Hereditary Disorder nonsyndromic recessive deafness DFNB1A4.42E-03 Neurological Disease nonsyndromic recessive deafness DFNB1A4.42E-03 Cellular Function and Maintenance organization of gonadal cell lines 4.42E-03 Reproductive System Development and Function organization of gonadal cell lines 4.42E-03 Skeletal and Muscular Disorders osteoporosis-pseudoglioma syndrome4.42E-03 Hereditary Disorder osteoporosis-pseudoglioma syndrome4.42E-03 Connective Tissue Disorders osteoporosis-pseudoglioma syndrome4.42E-03 Dermatological Diseases and Conditions pemphigus vulgaris 4.42E-03 Immunological Disease pemphigus vulgaris 4.42E-03 Cellular Assembly and Organization polarization of cell surface 4.42E-03 Cell Morphology polarization of cell surface 4.42E-03 Hereditary Disorder primary coenzyme Q10 deficiency type4.42E-03 2 Metabolic Disease primary coenzyme Q10 deficiency type4.42E-03 2 Cell Death and Survival quantity of apoptotic prostate cancer cell4.42E-03 lines Cellular Assembly and Organization remodeling of actin stress fibers 4.42E-03 Cellular Movement withdrawal of lamellipodia 4.42E-03 Developmental Disorder worth disease 4.42E-03 Skeletal and Muscular Disorders worth disease 4.42E-03 Hereditary Disorder worth disease 4.42E-03 Connective Tissue Disorders worth disease 4.42E-03 Cellular Growth and Proliferation proliferation of prostate cancer cell lines4.83E-03 Cellular Development proliferation of prostate cancer cell lines4.83E-03 Cell Morphology morphology of tumor cell lines 5.00E-03 Cancer hyperplasia 5.34E-03 Cell Cycle cell cycle progression 5.74E-03 Auditory Disease autosomal dominant deafness 5.85E-03 Hereditary Disorder autosomal dominant deafness 5.85E-03 Neurological Disease autosomal dominant deafness 5.85E-03 Cell Morphology morphology of breast cancer cell lines5.85E-03 Cancer invasion of cancer cells 7.24E-03 Cellular Movement invasion of cancer cells 7.24E-03 Tumor Morphology invasion of cancer cells 7.24E-03 Cell Death and Survival apoptosis of breast cancer cell lines 7.31E-03 Lipid Metabolism homeostasis of cholesterol 7.74E-03 Small Molecule Biochemistry homeostasis of cholesterol 7.74E-03 Vitamin and Mineral Metabolism homeostasis of cholesterol 7.74E-03 Cell Death and Survival apoptosis of epithelial cell lines 8.08E-03 Cancer squamous-cell carcinoma 8.22E-03 Cancer growth of tumor 8.25E-03 Developmental Disorder Van Buchem disease 8.83E-03 Skeletal and Muscular Disorders Van Buchem disease 8.83E-03 Connective Tissue Disorders Van Buchem disease 8.83E-03 Dermatological Diseases and Conditions Vohwinkel syndrome 8.83E-03 Hereditary Disorder Vohwinkel syndrome 8.83E-03 Organismal Injury and Abnormalities Vohwinkel syndrome 8.83E-03 Tissue Development aggregation of melanoma cell lines 8.83E-03 Tissue Development aggregation of squamous cell carcinoma8.83E-03 cell lines Tissue Development aggregation of stomach cancer cell lines8.83E-03 Cell-To-Cell Signaling and Interaction binding of lymphoid cells 8.83E-03 Small Molecule Biochemistry catabolism of D-glucose 8.83E-03 Carbohydrate Metabolism catabolism of D-glucose 8.83E-03 Cell-To-Cell Signaling and Interaction cell-cell adhesion of carcinoma cell lines8.83E-03 Tissue Development cell-cell adhesion of carcinoma cell lines8.83E-03 Cell-To-Cell Signaling and Interaction cell-cell adhesion of lung cancer cell lines8.83E-03 Tissue Development cell-cell adhesion of lung cancer cell lines8.83E-03 Cell-To-Cell Signaling and Interaction cell-cell contact of prostate cancer cell8.83E-03 lines Tissue Development cell-cell contact of prostate cancer cell8.83E-03 lines Tissue Development clustering of colon cancer cell lines 8.83E-03 Cell-To-Cell Signaling and Interaction compaction of stomach cancer cell lines8.83E-03 Cellular Assembly and Organization compaction of stomach cancer cell lines8.83E-03 Tissue Development compaction of stomach cancer cell lines8.83E-03 Developmental Disorder congenital cystic adenomatoid malformation8.83E-03 Respiratory Disease congenital cystic adenomatoid malformation8.83E-03 Tissue Morphology density of brain cancer cell lines 8.83E-03 Cell Cycle entry into S phase of endothelial cell lines8.83E-03 Cellular Development epithelial-mesenchymal transition of skin8.83E-03 cancer cell lines Cell-To-Cell Signaling and Interaction formation of cell-matrix contacts 8.83E-03 Cellular Assembly and Organization formation of cell-matrix contacts 8.83E-03 Cellular Function and Maintenance function of tight junctions 8.83E-03 Cell-To-Cell Signaling and Interaction function of tight junctions 8.83E-03 Cellular Assembly and Organization function of tight junctions 8.83E-03 Tissue Development function of tight junctions 8.83E-03 Cellular Growth and Proliferation generation of epithelial cell lines 8.83E-03 Tissue Development generation of epithelial cell lines 8.83E-03 Cellular Movement mobility of brain cancer cell lines 8.83E-03 Cellular Movement mobilization of breast cancer cell lines8.83E-03 Cellular Movement mobilization of melanoma cell lines 8.83E-03 Cellular Development morphogenesis of breast cancer cell lines8.83E-03 Cell Morphology morphogenesis of breast cancer cell lines8.83E-03 Cellular Development morphogenesis of melanoma cell lines8.83E-03 Cell Morphology morphogenesis of melanoma cell lines8.83E-03 Cell Morphology morphology of skin cancer cell lines 8.83E-03 Cellular Function and Maintenance organization of luminal epithelial cells 8.83E-03 Tissue Development organization of luminal epithelial cells 8.83E-03 Cellular Function and Maintenance organization of myoepithelial cells 8.83E-03 Tissue Development organization of myoepithelial cells 8.83E-03 Skeletal and Muscular System Development and Functionorganization of myoepithelial cells 8.83E-03 Molecular Transport secretion of green fluorescent protein 8.83E-03 Protein Trafficking secretion of green fluorescent protein 8.83E-03 Skeletal and Muscular System Development and Functionthickness of bone 8.83E-03 Organ Morphology thickness of bone 8.83E-03 Cellular Movement transmigration of vascular endothelial 8.83E-03cells Cardiovascular System Development and Function transmigration of vascular endothelial 8.83E-03cells Dermatological Diseases and Conditions epidermal hyperplasia 1.16E-02 Cancer epidermal hyperplasia 1.16E-02 Cancer head and neck cancer 1.27E-02 Cell-To-Cell Signaling and Interaction adhesion of kidney cancer cell lines 1.32E-02 Tissue Development adhesion of kidney cancer cell lines 1.32E-02 Cell-To-Cell Signaling and Interaction adhesion of skin cancer cell lines 1.32E-02 Tissue Development adhesion of skin cancer cell lines 1.32E-02 Tissue Development aggregation of bone cancer cell lines 1.32E-02 Tissue Development aggregation of gonadal cell lines 1.32E-02 Reproductive System Development and Function aggregation of gonadal cell lines 1.32E-02 Cancer atypical adenomatous lung hyperplasia1.32E-02 Small Molecule Biochemistry catabolism of L-serine 1.32E-02 Amino Acid Metabolism catabolism of L-serine 1.32E-02 Cell-To-Cell Signaling and Interaction cell-cell adhesion of keratinocytes 1.32E-02 Tissue Development cell-cell adhesion of keratinocytes 1.32E-02 Hair and Skin Development and Function cell-cell adhesion of keratinocytes 1.32E-02 Cell-To-Cell Signaling and Interaction cell-cell adhesion of prostate cancer cell1.32E-02 lines Tissue Development cell-cell adhesion of prostate cancer cell1.32E-02 lines Cell-To-Cell Signaling and Interaction cell-cell contact of keratinocytes 1.32E-02 Tissue Development cell-cell contact of keratinocytes 1.32E-02 Hair and Skin Development and Function cell-cell contact of keratinocytes 1.32E-02 Cell-To-Cell Signaling and Interaction clustering of Langerhans cells 1.32E-02 Tissue Development clustering of Langerhans cells 1.32E-02 Hematological System Development and Function clustering of Langerhans cells 1.32E-02 Immune Cell Trafficking clustering of Langerhans cells 1.32E-02 Inflammatory Response clustering of Langerhans cells 1.32E-02 Cell Cycle entry into S phase of colon cancer cell1.32E-02 lines Cell Cycle entry into S phase of kidney cell lines 1.32E-02 Renal and Urological System Development and Functionentry into S phase of kidney cell lines 1.32E-02 Cancer invasion of adenocarcinoma cells 1.32E-02 Cellular Movement invasion of adenocarcinoma cells 1.32E-02 Tumor Morphology invasion of adenocarcinoma cells 1.32E-02 Cellular Movement invasion of lung cell lines 1.32E-02 Small Molecule Biochemistry metabolism of folic acid 1.32E-02 Vitamin and Mineral Metabolism metabolism of folic acid 1.32E-02 Amino Acid Metabolism metabolism of folic acid 1.32E-02 Drug Metabolism metabolism of folic acid 1.32E-02 Cell Morphology polarity of breast cell lines 1.32E-02 Cell-To-Cell Signaling and Interaction quantity of intercellular junctions 1.32E-02 Cellular Assembly and Organization quantity of intercellular junctions 1.32E-02 Tissue Development quantity of intercellular junctions 1.32E-02 Cellular Assembly and Organization redistribution of membrane rafts 1.32E-02 Cell Morphology transepithelial electrical resistance of bronchial1.32E-02 epithelial cells Hair and Skin Development and Function transepithelial electrical resistance of bronchial1.32E-02 epithelial cells Tissue Development adhesion of extracellular matrix 1.41E-02 Renal and Urological Disease diabetic nephropathy 1.75E-02 Cellular Assembly and Organization accumulation of lipid droplets 1.76E-02 Lipid Metabolism accumulation of lipid droplets 1.76E-02 Small Molecule Biochemistry accumulation of lipid droplets 1.76E-02 Cell-To-Cell Signaling and Interaction activation of skin cancer cell lines 1.76E-02 Cell-To-Cell Signaling and Interaction activation of squamous cell carcinoma1.76E-02 cell lines Cell-To-Cell Signaling and Interaction adhesion of bone cancer cell lines 1.76E-02 Tissue Development adhesion of bone cancer cell lines 1.76E-02 Cell-To-Cell Signaling and Interaction binding of carcinoma cells 1.76E-02 Cancer binding of carcinoma cells 1.76E-02 Small Molecule Biochemistry biosynthesis of ubiquinone 1.76E-02 Cellular Assembly and Organization elongation of microvilli 1.76E-02 Cell Morphology elongation of microvilli 1.76E-02 Cell Cycle entry into S phase of fibroblasts 1.76E-02 Connective Tissue Development and Function entry into S phase of fibroblasts 1.76E-02 Cancer invasion of melanoma cells 1.76E-02 Cellular Movement invasion of melanoma cells 1.76E-02 Tumor Morphology invasion of melanoma cells 1.76E-02 Tissue Development morphogenesis of bone 1.76E-02 Connective Tissue Development and Function morphogenesis of bone 1.76E-02 Embryonic Development morphogenesis of bone 1.76E-02 Skeletal and Muscular System Development and Functionmorphogenesis of bone 1.76E-02 Organ Morphology morphogenesis of bone 1.76E-02 Organ Development morphogenesis of bone 1.76E-02 Organismal Development morphogenesis of bone 1.76E-02 Connective Tissue Development and Function quantity of osteoclasts 1.76E-02 Tissue Morphology quantity of osteoclasts 1.76E-02 Cell Morphology size of breast cancer cell lines 1.76E-02 Cell Signaling transduction of protein 1.76E-02 Vitamin and Mineral Metabolism metabolism of vitamin 1.76E-02 Cellular Movement invasion of brain cancer cell lines 1.83E-02 Cellular Development differentiation of keratinocytes 1.91E-02 Hair and Skin Development and Function differentiation of keratinocytes 1.91E-02 Cellular Growth and Proliferation proliferation of epithelial cells 2.02E-02 Cellular Growth and Proliferation proliferation of keratinocytes 2.06E-02 Cellular Development proliferation of keratinocytes 2.06E-02 Hair and Skin Development and Function proliferation of keratinocytes 2.06E-02 Cancer serous ovarian carcinoma process 2.11E-02 Endocrine System Disorders serous ovarian carcinoma process 2.11E-02 Reproductive System Disease serous ovarian carcinoma process 2.11E-02 Tissue Development adherence of cells 2.19E-02 Tissue Development aggregation of breast cancer cell lines2.19E-02 Cell Death and Survival anoikis of epithelial cell lines 2.19E-02 Developmental Disorder anophthalmia 2.19E-02 Ophthalmic Disease anophthalmia 2.19E-02 Dermatological Diseases and Conditions bullous pemphigoid 2.19E-02 Immunological Disease bullous pemphigoid 2.19E-02 Cell-To-Cell Signaling and Interaction cell-cell adhesion of breast cancer cell2.19E-02 lines Tissue Development cell-cell adhesion of breast cancer cell2.19E-02 lines Cell-To-Cell Signaling and Interaction cell-cell adhesion of breast cell lines 2.19E-02 Tissue Development cell-cell adhesion of breast cell lines 2.19E-02 Cancer childhood pro-B-cell acute lymphoblastic2.19E-02 leukemia Hematological Disease childhood pro-B-cell acute lymphoblastic2.19E-02 leukemia Immunological Disease childhood pro-B-cell acute lymphoblastic2.19E-02 leukemia Cellular Development differentiation of epithelial cell lines 2.19E-02 Hair and Skin Development and Function differentiation of epithelial cell lines 2.19E-02 Cell-To-Cell Signaling and Interaction disruption of adherens junctions 2.19E-02 Cellular Assembly and Organization disruption of adherens junctions 2.19E-02 Cellular Compromise disruption of adherens junctions 2.19E-02 Cellular Development epithelial to mesenchymal transdifferentiation2.19E-02 of breast cell lines Reproductive System Development and Function epithelial to mesenchymal transdifferentiation2.19E-02 of breast cell lines Visual System Development and Function metabolism of retina 2.19E-02 Cellular Development differentiation of osteoblasts 2.22E-02 Skeletal and Muscular System Development and Functiondifferentiation of osteoblasts 2.22E-02 Cancer small cell lung cancer 2.30E-02 Respiratory Disease small cell lung cancer 2.30E-02 Cell-To-Cell Signaling and Interaction adhesion of breast cancer cell lines 2.46E-02 Tissue Development adhesion of breast cancer cell lines 2.46E-02 Cellular Growth and Proliferation proliferation of cells 2.58E-02 Cell Death and Survival anoikis of breast cell lines 2.63E-02 Cell Death and Survival apoptosis of sympathetic neuron 2.63E-02 Cellular Growth and Proliferation colony formation of kidney cell lines 2.63E-02 Renal and Urological System Development and Functioncolony formation of kidney cell lines 2.63E-02 Cellular Development differentiation of breast cancer cell lines2.63E-02 Cellular Movement invasion of skin cell lines 2.63E-02 Cellular Growth and Proliferation proliferation of adenocarcinoma cells 2.63E-02 Cellular Development proliferation of adenocarcinoma cells 2.63E-02 Tumor Morphology proliferation of adenocarcinoma cells 2.63E-02 Cancer synovial sarcoma 2.63E-02 Small Molecule Biochemistry synthesis of purine base 2.63E-02 Nucleic Acid Metabolism synthesis of purine base 2.63E-02 Cellular Assembly and Organization transport of sorting endosomes 2.63E-02 Cancer tumorigenesis of prostate cancer cell lines2.63E-02 Reproductive System Disease tumorigenesis of prostate cancer cell lines2.63E-02 Cellular Movement invasion of tumor cell lines 2.77E-02 Cell Signaling MAPKKK cascade 2.80E-02 Cancer anaplastic thyroid carcinoma 3.06E-02 Endocrine System Disorders anaplastic thyroid carcinoma 3.06E-02 Cellular Growth and Proliferation colony formation of embryonic cell lines3.06E-02 Embryonic Development colony formation of embryonic cell lines3.06E-02 Cardiovascular Disease degenerative mitral valve disease 3.06E-02 Endocrine System Disorders glucose intolerance 3.06E-02 Skeletal and Muscular System Development and Functionsize of bone 3.06E-02 Organ Morphology size of bone 3.06E-02 Cellular Development transdifferentiation of tumor cell lines 3.06E-02 Cancer diffuse adenocarcinoma 3.49E-02 Cell-To-Cell Signaling and Interaction disruption of intercellular junctions 3.49E-02 Cellular Assembly and Organization disruption of intercellular junctions 3.49E-02 Tissue Development disruption of intercellular junctions 3.49E-02 Cellular Compromise disruption of intercellular junctions 3.49E-02 Cellular Function and Maintenance extension of axons 3.49E-02 Cellular Assembly and Organization extension of axons 3.49E-02 Cell Morphology extension of axons 3.49E-02 Nervous System Development and Function extension of axons 3.49E-02 Cancer malignant mixed Mullerian tumor 3.49E-02 Reproductive System Disease malignant mixed Mullerian tumor 3.49E-02 Cell Morphology morphology of hepatoma cell lines 3.49E-02 Cellular Growth and Proliferation proliferation of mesenchymal cells 3.49E-02 Cellular Development proliferation of mesenchymal cells 3.49E-02 Embryonic Development proliferation of mesenchymal cells 3.49E-02 Cell-To-Cell Signaling and Interaction release of dopamine 3.49E-02 Small Molecule Biochemistry release of dopamine 3.49E-02 Molecular Transport release of dopamine 3.49E-02 Drug Metabolism release of dopamine 3.49E-02 Cancer stomach tumor 3.49E-02 Gastrointestinal Disease stomach tumor 3.49E-02 Tissue Development development of epidermis 3.64E-02 Embryonic Development development of epidermis 3.64E-02 Hair and Skin Development and Function development of epidermis 3.64E-02 Organ Development development of epidermis 3.64E-02 Organismal Development development of epidermis 3.64E-02 Cell Cycle entry into S phase 3.74E-02 Cell Death and Survival apoptosis of tumor cell lines 3.86E-02 Cellular Movement cell movement of tumor cell lines 3.88E-02 Cancer carcinoma in situ 3.88E-02 Hematological System Development and Function cell viability of natural killer cells 3.91E-02 Cell Death and Survival cell viability of natural killer cells 3.91E-02 Cellular Growth and Proliferation colony formation of epithelial cell lines3.91E-02 Hair and Skin Development and Function colony formation of epithelial cell lines3.91E-02 Cell Morphology morphology of bone cancer cell lines 3.91E-02 Molecular Transport transport of monocarboxylic acid 3.91E-02 Cellular Movement migration of tumor cell lines 4.08E-02 Hematological System Development and Function chemotaxis of neutrophils 4.14E-02 Cellular Movement chemotaxis of neutrophils 4.14E-02 Immune Cell Trafficking chemotaxis of neutrophils 4.14E-02 Inflammatory Response chemotaxis of neutrophils 4.14E-02 Cell Death and Survival anoikis of breast cancer cell lines 4.34E-02 Cell Death and Survival apoptosis of acute lymphoblastic leukemia4.34E-02 cells Tumor Morphology apoptosis of acute lymphoblastic leukemia4.34E-02 cells Cellular Movement migration of skin cancer cell lines 4.34E-02 Cellular Movement migration of brain cancer cell lines 4.35E-02 Cell Cycle interphase of breast cancer cell lines 4.56E-02 Cancer genital tumor 4.56E-02 Reproductive System Disease genital tumor 4.56E-02 Cellular Movement cell movement of prostate cancer cell 4.67E-02lines Cancer Cancer 4.70E-02 Gene Expression transcription of DNA 4.70E-02 Cardiovascular System Development and Function QT interval of heart 4.76E-02 Cellular Movement cell movement of mammary tumor cells4.76E-02 Cellular Growth and Proliferation co-stimulation of T lymphocytes 4.76E-02 Cell-To-Cell Signaling and Interaction co-stimulation of T lymphocytes 4.76E-02 Hematological System Development and Function co-stimulation of T lymphocytes 4.76E-02 Cellular Movement invasion of bone cancer cell lines 4.76E-02 Cellular Movement migration of neuroblastoma cell lines 4.76E-02 Cellular Function and Maintenance organization of endosomes 4.76E-02 Cellular Assembly and Organization organization of endosomes 4.76E-02 Cancer tumorigenesis of cells 4.77E-02 Developmental Disorder congenital anomaly of musculoskeletal4.87E-02 system Skeletal and Muscular Disorders congenital anomaly of musculoskeletal4.87E-02 system Molecules # Molecules CDH1,DSC2 2 CDH1,CRABP2,SERPINB5 3 ATP1B1,CD24,CDH1,CRABP2,DSC2,FABP5,GJB2,LAD1,PITX1,SERPINB510 CD24,CDH1 2 CD24,CDH1 2 CD24,CDH1 2 CRB3,MPP7 2 CRB3,MPP7 2 CRB3,MPP7 2 CRB3,MPP7 2 CDH1,SOX2 2 CRB3,GJB2,MPP7 3 CRB3,GJB2,MPP7 3 CRB3,GJB2,MPP7 3 CRB3,GJB2,MPP7 3 CRB3,GJB2,MPP7 3 CDH1,SERPINB5 2 CDH1,SERPINB5 2 CD24,FABP5,GJB2,SERPINB5 4 SIAH1,SYK 2 ANO1,CD24,SYK 3 CD24,CDH1,SERPINB5 3 CD24,CDH1,SERPINB5 3 CD24,CDH1,SERPINB5 3 CASK,GJB2,PITX1 3 CASK,GJB2,PITX1 3 CD24,CDH1,CRABP2,SERPINB5 4 CD24,IGFBP2 2 CD24,IGFBP2 2 CD24,IGFBP2 2 CDH1,FABP5,SERPINB5 3 CDH1,SERPINB5 2 CDH1,SERPINB5 2 CDH1,SERPINB5 2 GJB2,GRHL2 2 GJB2,GRHL2 2 GJB2,GRHL2 2 GJB2,GRHL2 2 GJB2,GRHL2 2 CDH1,ID3,IGFBP2,SIAH1,SOX2,SYK,TFCP2L17 GJB2 1 GJB2 1 GJB2 1 GJB2 1 GJB2 1 SOX2 1 SOX2 1 SOX2 1 LRP5 1 LRP5 1 LRP5 1 SYK 1 SYK 1 SYK 1 SYK 1 SERPINB5 1 SERPINB5 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 DSC2 1 DSC2 1 GJB2 1 GJB2 1 GJB2 1 LRP5 1 LRP5 1 LRP5 1 LRP5 1 LRP5 1 LRP5 1 CDS1 1 CDS1 1 CD24 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 SYK 1 PITX1 1 PITX1 1 SIAH1 1 SIAH1 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 PDSS1 1 CASK 1 CASK 1 GRHL2 1 GRHL2 1 PIGM 1 BCL11A 1 BCL11A 1 SIAH1 1 GJB2 1 GJB2 1 GJB2 1 GJB2 1 SERPINB5 1 SERPINB5 1 SERPINB5 1 GJB2 1 GJB2 1 GJB2 1 GJB2 1 GJB2 1 GJB2 1 GJB2 1 GJB2 1 CDH1 1 CDH1 1 GRHL2 1 GRHL2 1 GRHL2 1 GJB2 1 GJB2 1 GJB2 1 CDH1 1 CDH1 1 LRP5 1 LRP5 1 LRP5 1 CDH1 1 CDH1 1 RAB3IP 1 RAB3IP 1 PDSS1 1 PDSS1 1 SERPINB5 1 RAB3IP 1 SERPINB5 1 LRP5 1 LRP5 1 LRP5 1 LRP5 1 CDH1,FABP5,IGFBP2,MST4,SERPINB55 CDH1,FABP5,IGFBP2,MST4,SERPINB55 CDH1,LRP5,SERPINB5,SIAH1 4 CD24,CDH1,IGFBP2,LAD1 4 CD24,CDH1,ID3,LRP5,OVOL2,SERPINB5,SIAH1,SOX2,SYK9 GJB2,GRHL2 2 GJB2,GRHL2 2 GJB2,GRHL2 2 SERPINB5,SIAH1 2 CDH1,SERPINB5 2 CDH1,SERPINB5 2 CDH1,SERPINB5 2 CDH1,CRABP2,GRHL2,MST4,SERPINB55 CD24,LRP5 2 CD24,LRP5 2 CD24,LRP5 2 CDH1,GRHL2,MST4,SIAH1 4 ANO1,ATP1B1,BCL11A,CD24,SYK5 IGFBP2,SERPINB5 2 LRP5 1 LRP5 1 LRP5 1 GJB2 1 GJB2 1 GJB2 1 CDH1 1 CDH1 1 CDH1 1 SYK 1 LRP5 1 LRP5 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 IGFBP2 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 MPP7 1 MPP7 1 MPP7 1 MPP7 1 GRHL2 1 GRHL2 1 IGFBP2 1 SERPINB5 1 SERPINB5 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 DSC2 1 DSC2 1 DSC2 1 DSC2 1 DSC2 1 SORL1 1 SORL1 1 LRP5 1 LRP5 1 ID3 1 ID3 1 CD24,LAD1 2 CD24,LAD1 2 ANO1,CD24,CDH1,FABP5,IGFBP2,SOX2,SYK7 CDH1 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 SHMT1 1 SHMT1 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 SERPINB5 1 SERPINB5 1 SERPINB5 1 CDH1 1 SHMT1 1 SHMT1 1 SHMT1 1 SHMT1 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 SYK 1 CDH1 1 CDH1 1 CASK,CDH1 2 CD24,CDS1,IGFBP2 3 SORL1 1 SORL1 1 SORL1 1 CDH1 1 CDH1 1 LRP5 1 LRP5 1 CD24 1 CD24 1 PDSS1 1 CDH1 1 CDH1 1 ID3 1 ID3 1 CDH1 1 CDH1 1 CDH1 1 LRP5 1 LRP5 1 LRP5 1 LRP5 1 LRP5 1 LRP5 1 LRP5 1 LRP5 1 LRP5 1 IGFBP2 1 SYK 1 RDH10,SHMT1 2 CD24,IGFBP2 2 CDH1,OVOL2 2 CDH1,OVOL2 2 CASK,OVOL2,SOX2 3 CASK,OVOL2 2 CASK,OVOL2 2 CASK,OVOL2 2 CD24,CMTM4,IGFBP2 3 CD24,CMTM4,IGFBP2 3 CD24,CMTM4,IGFBP2 3 CDH1 1 CDH1 1 GRHL2 1 SOX2 1 SOX2 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 SYK 1 SYK 1 SYK 1 GRHL2 1 GRHL2 1 CDH1 1 CDH1 1 CDH1 1 GRHL2 1 GRHL2 1 RDH10 1 LRP5,SOX2 2 LRP5,SOX2 2 CDH1,SOX2 2 CDH1,SOX2 2 CDH1,SERPINB5 2 CDH1,SERPINB5 2 CASK,CD24,CDH1,CKLF,CRABP2,EPHA1,FABP5,GJB2,ID3,IGFBP2,LRP5,MEST,MST4,MTUS1,OVOL2,SERPINB5,SIAH1,SOX2,SYK19 GRHL2 1 SIAH1 1 MST4 1 MST4 1 GRHL2 1 CDH1 1 ID3 1 ID3 1 ID3 1 CDH1 1 SHMT1 1 SHMT1 1 HOOK1 1 MST4 1 MST4 1 CD24,CDH1,FABP5,IGFBP2,LRP5,SERPINB56 CD24,SOX2 2 CDH1 1 CDH1 1 MST4 1 MST4 1 LRP5 1 IGFBP2 1 LRP5 1 LRP5 1 GRHL2 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 CDH1 1 BCL11A 1 BCL11A 1 BCL11A 1 BCL11A 1 CDH1 1 CDH1 1 CDH1 1 LRP5 1 LRP5 1 LRP5 1 SIAH1 1 SIAH1 1 SIAH1 1 SIAH1 1 CDH1,COBLL1,SIAH1,SOX2 4 CDH1,COBLL1,SIAH1,SOX2 4 CRABP2,FABP5 2 CRABP2,FABP5 2 CRABP2,FABP5 2 CRABP2,FABP5 2 CRABP2,FABP5 2 CDH1,ID3 2 CD24,CDH1,CRABP2,GRHL2,ID3,MST4,OGFOD1,SERPINB5,SIAH1,SYK10 CD24,CDH1,CKLF,IGFBP2,LRP5,SERPINB5,SYK7 PAPD5,SLC16A5,TFCP2L1 3 SYK 1 SYK 1 MST4 1 MST4 1 LRP5 1 SLC16A5 1 CD24,CDH1,CKLF,IGFBP2,SERPINB5,SYK6 CKLF,SYK 2 CKLF,SYK 2 CKLF,SYK 2 CKLF,SYK 2 GRHL2 1 CD24 1 CD24 1 CDH1 1 CD24,IGFBP2 2 CDH1,SOX2 2 CD24,CDH1,CGN,CMTM4,IGFBP2,LRP5,SERPINB5,SLC16A5,SOX29 CD24,CDH1,CGN,CMTM4,IGFBP2,LRP5,SERPINB5,SLC16A5,SOX29 CDH1,SERPINB5 2 ANO1,ATP1B1,BCL11A,CD24,CDH1,CGN,CMTM4,CNOT1,COBLL1,CRABP2,EPHA1,FABP5,FZD1,GJB2,GRHL2,IGFBP2,LAD1,LRP5,MEST,PAPD5,SERPINB5,SIAH1,SLC16A5,SORL1,SOX2,SYK,TFCP2L127 BCL11A,CDH1,CRABP2,FZD1,ID3,LRP5,NFIB,SOX2,TFCP2L19 CNOT1 1 SERPINB5 1 CD24 1 CD24 1 CD24 1 LRP5 1 CKLF 1 HOOK1 1 HOOK1 1 MST4,PITX1 2 CASK,GJB2,LRP5,PITX1 4 CASK,GJB2,LRP5,PITX1 4 Supplementary Table 4: Functional pathways with erlotinib resistance in HNC and NSCLC

© 2000-2013 Ingenuity Systems, Inc. All rights reserved. Category Functions Annotationp-Value Molecules # Molecules Cancer Cancer 3.03E-10 ADAM19,ANTXR2,AXL,BST2,CA9,CCL5,CD70,CDA,CDH2,CMPK2,COL6A1,COL6A2,CPEB2,CTGF,CXCL10,EMP3,EPSTI1,FAM20C,FAM46C,FERMT2,GAS1,GNG11,HIST1H2BD,IDO1,IFIT1,IFIT2,IFIT3,IFITM1,IL32,IL6,IL7R,IL8,ITGA5,KLF6,KRT81,LAMP3,LPAR1,MAFB,MSX1,NFE2L3,PMAIP1,PODXL,PRDM1,PTGER4,PVRL3,PXDN,RUNX3,SCG5,SERPINE2,SFRP1,SH2B3,SLC2A3,SLIT2,SOD2,TDO2,TGFBR3,TIMP1,TIMP258 Cancer colorectal cancer5.11E-10 AXL,BST2,CCL5,CDA,CDH2,COL6A1,COL6A2,CTGF,CXCL10,HIST1H2BD,IDO1,IFITM1,IL6,IL8,KLF6,LPAR1,MAFB,MSX1,PTGER4,PVRL3,RUNX3,SERPINE2,SFRP1,SLC2A3,SLIT2,SOD2,TGFBR3,TIMP1,TIMP229 Gastrointestinalcolorectal Disease cancer5.11E-10 AXL,BST2,CCL5,CDA,CDH2,COL6A1,COL6A2,CTGF,CXCL10,HIST1H2BD,IDO1,IFITM1,IL6,IL8,KLF6,LPAR1,MAFB,MSX1,PTGER4,PVRL3,RUNX3,SERPINE2,SFRP1,SLC2A3,SLIT2,SOD2,TGFBR3,TIMP1,TIMP229 Cancer epithelial neoplasia5.31E-10 ADAM19,ANTXR2,AXL,BST2,CA9,CCL5,CD70,CDA,CDH2,COL6A1,COL6A2,CTGF,CXCL10,EMP3,FAM20C,GAS1,HIST1H2BD,IDO1,IFIT1,IFIT3,IFITM1,IL32,IL6,IL8,ITGA5,KLF6,KRT81,LAMP3,LPAR1,MAFB,MSX1,NFE2L3,PMAIP1,PODXL,PRDM1,PTGER4,PVRL3,PXDN,RUNX3,SERPINE2,SFRP1,SLC2A3,SLIT2,SOD2,TDO2,TGFBR3,TIMP1,TIMP248 Cancer carcinoma 6.79E-10 ADAM19,ANTXR2,AXL,BST2,CA9,CCL5,CD70,CDA,CDH2,COL6A1,COL6A2,CTGF,CXCL10,EMP3,FAM20C,GAS1,HIST1H2BD,IDO1,IFIT1,IFIT3,IFITM1,IL6,IL8,ITGA5,KLF6,KRT81,LAMP3,LPAR1,MAFB,MSX1,NFE2L3,PMAIP1,PODXL,PRDM1,PTGER4,PVRL3,PXDN,RUNX3,SERPINE2,SFRP1,SLC2A3,SLIT2,SOD2,TDO2,TGFBR3,TIMP1,TIMP247 Dermatologicalpsoriasis Diseases4.28E-08 and ConditionsCXCL10,DDX58,EPSTI1,HERC6,IDO1,IFIT1,IFIT3,IFITM1,IL6,IL8,IRF7,ITGA5,LAMP3,OASL,RSAD2,RTP4,SOD2,TGFBR3,TIMP219 Cellular Growthproliferation and Proliferation4.98E-08 of cells AXL,BST2,CA9,CCL5,CD70,CDA,CDH2,COL6A1,COL6A2,CTGF,CXCL10,EIF5A2,EMILIN2,EMP3,FRMD6,IDO1,IFIT3,IL6,IL7R,IL8,ITGA5,KLF6,LAMP3,MSX1,NOV,PRDM1,PTGER4,PTPRE,PTPRM,PXDN,RUNX3,SERPINE2,SFRP1,SH2B3,SLIT2,SOD2,SPRY2,TGFBR3,TIMP1,TIMP240 Cellular Movementcell movement9.40E-08 of tumorAXL,CA9,CCL5,CDH2,CTGF,CXCL10,FERMT2,IL6,IL8,ITGA5,LPAR1,NOV,PODXL,PTPRM,SLIT2,SOD2,SPRY2,TIMP1,TIMP2 cell lines 19 Cancer digestive organ1.00E-07 tumor AXL,BST2,CA9,CCL5,CDA,CDH2,COL6A1,COL6A2,CTGF,CXCL10,HIST1H2BD,IDO1,IFITM1,IL6,IL8,KLF6,LPAR1,MAFB,MSX1,PTGER4,PVRL3,PXDN,RUNX3,SERPINE2,SFRP1,SLC2A3,SLIT2,SOD2,TDO2,TGFBR3,TIMP1,TIMP232 Gastrointestinaldigestive Disease organ1.00E-07 tumor AXL,BST2,CA9,CCL5,CDA,CDH2,COL6A1,COL6A2,CTGF,CXCL10,HIST1H2BD,IDO1,IFITM1,IL6,IL8,KLF6,LPAR1,MAFB,MSX1,PTGER4,PVRL3,PXDN,RUNX3,SERPINE2,SFRP1,SLC2A3,SLIT2,SOD2,TDO2,TGFBR3,TIMP1,TIMP232 Cellular Movementmigration of5.61E-07 tumor cell linesAXL,CA9,CCL5,CDH2,CXCL10,IL6,IL8,LPAR1,NOV,PODXL,PTPRM,SLIT2,SOD2,SPRY2,TIMP1,TIMP216 Cancer mammary tumor1.07E-06 CA9,CD70,CDH2,CMPK2,CPEB2,CTGF,EMP3,FERMT2,IFIT1,IL32,IL6,KLF6,LAMP3,LPAR1,PMAIP1,PRDM1,PTGER4,PXDN,SCG5,SFRP1,SLIT2,TIMP122 Cancer breast cancer2.16E-06 CA9,CD70,CDH2,CMPK2,CPEB2,CTGF,EMP3,FERMT2,IFIT1,IL32,IL6,KLF6,LAMP3,LPAR1,PMAIP1,PRDM1,PXDN,SCG5,SFRP1,SLIT2,TIMP121 Antimicrobialantiviral Response response7.26E-06 BST2,CCL5,DDX58,IFIT1,IFIT2,OASL6 Inflammatoryantiviral Response response7.26E-06 BST2,CCL5,DDX58,IFIT1,IFIT2,OASL6 Cancer uterine serous7.46E-06 papillaryCDA,GAS1,IL6,IL8,KRT81,LAMP3,NFE2L3,PMAIP1,SFRP1,TGFBR3 cancer 10 Reproductiveuterine System serous Disease7.46E-06 papillaryCDA,GAS1,IL6,IL8,KRT81,LAMP3,NFE2L3,PMAIP1,SFRP1,TGFBR3 cancer 10 Cell Death andcell survivalSurvival7.53E-06 ALPK2,ANTXR2,AXL,CA9,CCL5,CDH2,CTGF,CXCL10,EMILIN2,IL6,IL8,ITGA5,NOV,PTPRE,PTPRM,SFRP1,SOD2,TIMP1,TIMP219 Cellular Movementcell movement7.82E-06 of breastAXL,CCL5,CDH2,CXCL10,IL6,IL8,LPAR1,TIMP1,TIMP2 cancer cell9 lines Cancer uterine cancer8.36E-06 ANTXR2,CA9,CDA,CDH2,EMP3,GAS1,GNG11,IFIT1,IFIT3,IL6,IL8,KRT81,LAMP3,NFE2L3,PMAIP1,SFRP1,TGFBR3,TIMP118 Reproductiveuterine System cancer Disease8.36E-06 ANTXR2,CA9,CDA,CDH2,EMP3,GAS1,GNG11,IFIT1,IFIT3,IL6,IL8,KRT81,LAMP3,NFE2L3,PMAIP1,SFRP1,TGFBR3,TIMP118 Cancer benign neoplasia8.49E-06 ANTXR2,CTGF,GNG11,IFIT1,IFIT3,IL6,LPAR1,NOV,PTGER4,SERPINE2,SFRP1,SLIT2,SOD2,TGFBR314 Cellular Movementmigration of1.03E-05 cells AXL,CA9,CCL5,CDH2,CTGF,CXCL10,DDX58,IL6,IL8,ITGA5,LPAR1,NOV,PODXL,PTPRM,SFRP1,SLIT2,SOD2,SPRY2,TIMP1,TIMP220 Cancer endometrial1.42E-05 cancer ANTXR2,CDA,EMP3,GAS1,IL6,IL8,KRT81,LAMP3,NFE2L3,PMAIP1,SFRP1,TGFBR312 Reproductiveendometrial System Disease1.42E-05 cancer ANTXR2,CDA,EMP3,GAS1,IL6,IL8,KRT81,LAMP3,NFE2L3,PMAIP1,SFRP1,TGFBR312 Cell Death andcell viabilitySurvival1.42E-05 ALPK2,ANTXR2,AXL,CA9,CCL5,CDH2,CTGF,CXCL10,EMILIN2,IL6,IL8,NOV,PTPRE,PTPRM,SFRP1,SOD2,TIMP1,TIMP218 Cellular Movementmigration of1.64E-05 breast cancerAXL,CCL5,CDH2,CXCL10,IL6,IL8,TIMP1,TIMP2 cell lines8 Inflammatoryrelapsing-remitting Disease 1.74E-05 multipleEPSTI1,IFIT1,IRF7,RSAD2 sclerosis4 Neurologicalrelapsing-remitting Disease 1.74E-05 multipleEPSTI1,IFIT1,IRF7,RSAD2 sclerosis4 Skeletal andrelapsing-remitting Muscular Disorders1.74E-05 multipleEPSTI1,IFIT1,IRF7,RSAD2 sclerosis4 Cellular Movementcell movement1.91E-05 AXL,CA9,CCL5,CDH2,CTGF,CXCL10,DDX58,FERMT2,IL6,IL8,ITGA5,LPAR1,NOV,PODXL,PTPRM,SFRP1,SLIT2,SOD2,SPRY2,TIMP1,TIMP221 Cellular Movementinvasion of tumor2.46E-05 cell linesAXL,CDH2,IL8,ITGA5,LPAR1,NOV,PODXL,SERPINE2,SFRP1,SOD2,SPRY2,TIMP1,TIMP213 Cell Death andnecrosis Survival2.78E-05 ANTXR2,AXL,CCL5,CD70,CDA,CDH2,CTGF,DDX58,EMILIN2,EMP3,FRMD6,IDO1,IL32,IL6,IL7R,IL8,KLF6,LPAR1,MSX1,PMAIP1,PRDM1,RUNX3,SFRP1,SOD2,SPRY2,TGFBR3,TIMP127 Cellular Developmentdifferentiation3.41E-05 of cells CD70,CTGF,CXCL10,IL32,IL6,IL8,IRF7,MAFB,NOV,PRDM1,SERPINE2,SFRP1,SPANXC15 (includes others),TIMP1,TIMP2 Cellular Growthproliferation and Proliferation4.08E-05 of connectiveCTGF,IDO1,IL6,IL8,ITGA5,SFRP1,SOD2,SPRY2 tissue cells8 Cancer colon cancer4.16E-05 BST2,COL6A1,COL6A2,HIST1H2BD,IFITM1,IL6,IL8,KLF6,LPAR1,PVRL3,SLC2A3,SLIT2,TIMP1,TIMP214 Gastrointestinalcolon Disease cancer4.16E-05 BST2,COL6A1,COL6A2,HIST1H2BD,IFITM1,IL6,IL8,KLF6,LPAR1,PVRL3,SLC2A3,SLIT2,TIMP1,TIMP214 Cellular Movementinvasion of prostate5.24E-05 cancerIL8,LPAR1,PODXL,SERPINE2,SPRY2 cell lines5 Cancer renal cancer5.62E-05 ADAM19,CA9,CD70,IFIT3,IL6,KLF6,SFRP1,SOD2,TIMP1,TIMP210 Renal and Urologicalrenal cancer Disease5.62E-05 ADAM19,CA9,CD70,IFIT3,IL6,KLF6,SFRP1,SOD2,TIMP1,TIMP210 Infectious Diseasereplication of6.10E-05 HerpesviridaeDDX58,MX2,RSAD2,SPRY24 Cellular Movementmigration of6.31E-05 phagocytesCCL5,CXCL10,IL6,IL8,TIMP1,TIMP26 Inflammatorymigration Response of6.31E-05 phagocytesCCL5,CXCL10,IL6,IL8,TIMP1,TIMP26 Hematologicalmigration System of 6.31E-05Development phagocytesCCL5,CXCL10,IL6,IL8,TIMP1,TIMP2 and Function6 Immune Cellmigration Trafficking of6.31E-05 phagocytesCCL5,CXCL10,IL6,IL8,TIMP1,TIMP26 Cancer papillary renal6.77E-05 cell carcinomaSFRP1,TIMP1,TIMP23 Renal and Urologicalpapillary renal Disease6.77E-05 cell carcinomaSFRP1,TIMP1,TIMP23 Cancer adenocarcinoma8.26E-05 ANTXR2,CA9,CDA,EMP3,GAS1,IL6,IL8,ITGA5,KRT81,LAMP3,NFE2L3,PMAIP1,SERPINE2,SFRP1,SLIT2,TGFBR3,TIMP1,TIMP218 Infectious Diseasereplication of8.57E-05 Murine herpesvirusDDX58,MX2,SPRY2 43 Cell Death andcell deathSurvival of8.64E-05 phagocytesCCL5,IL6,IL8,PMAIP1,SOD25 Inflammatoryinflammatory Disease 8.80E-05 demyelinatingAXL,EPSTI1,IFIT1,IL7R,IRF7,RSAD2,TIMP1 disease7 Neurologicalinflammatory Disease 8.80E-05 demyelinatingAXL,EPSTI1,IFIT1,IL7R,IRF7,RSAD2,TIMP1 disease7 GastrointestinalHepatitis Disease9.39E-05 CCL5,CXCL10,IL6,IL8,SOD2,TIMP16 InflammatoryHepatitis Disease 9.39E-05 CCL5,CXCL10,IL6,IL8,SOD2,TIMP16 Hepatic SystemHepatitis Disease9.39E-05 CCL5,CXCL10,IL6,IL8,SOD2,TIMP16 Infectious Diseasesevere acute1.13E-04 respiratoryHIST1H2BD,IL6,SH2B3,SLC2A3,TIMP1,TIMP2 syndrome6 Respiratorysevere Disease acute1.13E-04 respiratoryHIST1H2BD,IL6,SH2B3,SLC2A3,TIMP1,TIMP2 syndrome6 Cell Death andcell deathSurvival1.13E-04 ANTXR2,AXL,CCL5,CD70,CDA,CDH2,CTGF,DDX58,EMILIN2,EMP3,FRMD6,IDO1,IL32,IL6,IL7R,IL8,ITGA5,KLF6,LPAR1,MSX1,PMAIP1,PRDM1,RUNX3,SFRP1,SLIT2,SOD2,SPRY2,TGFBR3,TIMP129 Cancer genital tumor1.19E-04 ANTXR2,AXL,CCL5,CDH2,IDO1,IL6,IL7R,IL8,KLF6,LPAR1,MSX1,PODXL,PTGER4,RUNX3,SFRP1,SLIT2,SOD2,TIMP118 Reproductivegenital System tumor Disease1.19E-04 ANTXR2,AXL,CCL5,CDH2,IDO1,IL6,IL7R,IL8,KLF6,LPAR1,MSX1,PODXL,PTGER4,RUNX3,SFRP1,SLIT2,SOD2,TIMP118 Skeletal andBethlem Muscular myopathy Disorders1.19E-04 COL6A1,COL6A22 Hereditary DisorderBethlem myopathy1.19E-04 COL6A1,COL6A22 Skeletal andUllrich Muscular congenital Disorders1.19E-04 muscularCOL6A1,COL6A2 dystrophy2 Hereditary DisorderUllrich congenital1.19E-04 muscularCOL6A1,COL6A2 dystrophy2 Cell Death andcell deathSurvival of1.19E-04 sarcoma cellEMILIN2,SFRP1 lines 2 Cardiovascularmineralization Disease1.19E-04 of vascularAXL,IL6 smooth muscle2 cells Cell Morphologymineralization1.19E-04 of vascularAXL,IL6 smooth muscle2 cells Inflammatorypyelonephritis Response1.19E-04 IL6,IL8 2 Inflammatorypyelonephritis Disease 1.19E-04 IL6,IL8 2 Renal and Urologicalpyelonephritis Disease1.19E-04 IL6,IL8 2 Cell Death andcell deathSurvival of1.27E-04 myeloid cellsCCL5,IL6,IL8,PMAIP1,SOD25 Cell Death andapoptosis Survival1.42E-04 AXL,CCL5,CD70,CDH2,CTGF,DDX58,EMILIN2,IDO1,IL32,IL6,IL7R,IL8,ITGA5,KLF6,LPAR1,MSX1,PMAIP1,PRDM1,RUNX3,SFRP1,SLIT2,SOD2,SPRY2,TGFBR3,TIMP125 Cancer hematologic1.44E-04 cancer AXL,CD70,EPSTI1,FAM46C,IFIT2,IFIT3,IL6,IL7R,IL8,ITGA5,PXDN,SH2B3,SOD213 Hematologicalhematologic Disease1.44E-04 cancer AXL,CD70,EPSTI1,FAM46C,IFIT2,IFIT3,IL6,IL7R,IL8,ITGA5,PXDN,SH2B3,SOD213 Cell-To-Celladhesion Signaling of and1.45E-04 tumor Interaction cell linesCDH2,CXCL10,IL6,IL8,ITGA5,NOV,PVRL3,SLIT28 Tissue Developmentadhesion of1.45E-04 tumor cell linesCDH2,CXCL10,IL6,IL8,ITGA5,NOV,PVRL3,SLIT28 Cancer prostate cancer1.64E-04 ANTXR2,CCL5,CDH2,IDO1,IL6,IL7R,KLF6,LPAR1,PODXL,RUNX3,SFRP1,SOD2,TIMP113 Reproductiveprostate System cancer Disease1.64E-04 ANTXR2,CCL5,CDH2,IDO1,IL6,IL7R,KLF6,LPAR1,PODXL,RUNX3,SFRP1,SOD2,TIMP113 Cell Death andapoptosis Survival of1.86E-04 fibrosarcomaDDX58,EMILIN2,PMAIP1,SOD2 cell lines4 Cellular Movementtransmigration1.86E-04 of phagocytesCCL5,IL6,IL8,TIMP24 Inflammatorytransmigration Response1.86E-04 of phagocytesCCL5,IL6,IL8,TIMP24 Hematologicaltransmigration System 1.86E-04Development of phagocytesCCL5,IL6,IL8,TIMP2 and Function4 Immune Celltransmigration Trafficking1.86E-04 of phagocytesCCL5,IL6,IL8,TIMP24 Cancer hematological2.02E-04 neoplasiaAXL,CD70,CXCL10,EPSTI1,FAM46C,IFIT2,IFIT3,IL6,IL7R,IL8,ITGA5,PRDM1,PXDN,SH2B3,SOD215 Hematologicalhematological Disease2.02E-04 neoplasiaAXL,CD70,CXCL10,EPSTI1,FAM46C,IFIT2,IFIT3,IL6,IL7R,IL8,ITGA5,PRDM1,PXDN,SH2B3,SOD215 Cellular Developmentdifferentiation2.19E-04 of blood cellsCD70,IL6,IL8,IRF7,MAFB,PRDM1,SFRP1,TIMP18 Hematologicaldifferentiation System 2.19E-04Development of blood cellsCD70,IL6,IL8,IRF7,MAFB,PRDM1,SFRP1,TIMP1 and Function8 Cellular Growthproliferation and Proliferation2.23E-04 of prostateIL6,KLF6,SFRP1 cell lines 3 Cellular Developmentproliferation2.23E-04 of prostateIL6,KLF6,SFRP1 cell lines 3 Reproductiveproliferation System Development2.23E-04 of prostateIL6,KLF6,SFRP1 cell and lines Function3 Tissue Developmentaggregation2.34E-04 of cells CDH2,CXCL10,IL6,ITGA5,SERPINE2,TIMP26 Cell Death andapoptosis Survival of2.37E-04 mesangialCTGF,SOD2 cells 2 Cellular Developmentbranching of2.37E-04 epithelial cellsTIMP1,TIMP22 Cell Morphologybranching of2.37E-04 epithelial cellsTIMP1,TIMP22 Tissue Developmentbranching of2.37E-04 epithelial cellsTIMP1,TIMP22 Embryonic Developmentbranching of2.37E-04 epithelial cellsTIMP1,TIMP22 Cellular Movementinvasion of blood-derived2.37E-04 TIMP1,TIMP2 mast cells2 Inflammatoryinvasion Response of blood-derived2.37E-04 TIMP1,TIMP2 mast cells2 Immune Cellinvasion Trafficking of blood-derived2.37E-04 TIMP1,TIMP2 mast cells2 Hypersensitivityinvasion Response of blood-derived2.37E-04 TIMP1,TIMP2 mast cells2 Cancer pancreatic adenocarcinoma2.39E-04 AXL,IFITM1,SERPINE2,TIMP14 Gastrointestinalpancreatic Disease adenocarcinoma2.39E-04 AXL,IFITM1,SERPINE2,TIMP14 Endocrine Systempancreatic Disorders adenocarcinoma2.39E-04 AXL,IFITM1,SERPINE2,TIMP14 Cancer B-cell leukemia2.53E-04 CD70,IL6,IL7R,IL8,ITGA5,PXDN6 HematologicalB-cell Disease leukemia2.53E-04 CD70,IL6,IL7R,IL8,ITGA5,PXDN6 ImmunologicalB-cell Disease leukemia2.53E-04 CD70,IL6,IL7R,IL8,ITGA5,PXDN6 Cardiovascularangiogenesis System2.70E-04 DevelopmentAXL,IL6,IL8,ITGA5,PTPRM,SLIT2,TGFBR3,TIMP2 and Function8 Cancer lymphohematopoietic3.40E-04 cancerAXL,CD70,CXCL10,EPSTI1,FAM46C,IFIT2,IFIT3,IL6,IL7R,IL8,ITGA5,PRDM1,PXDN,SH2B3,SOD215 Cancer pancreatic cancer3.47E-04 AXL,CDH2,IDO1,IFITM1,IL6,PXDN,SERPINE2,TIMP18 Gastrointestinalpancreatic Disease cancer3.47E-04 AXL,CDH2,IDO1,IFITM1,IL6,PXDN,SERPINE2,TIMP18 Endocrine Systempancreatic Disorders cancer3.47E-04 AXL,CDH2,IDO1,IFITM1,IL6,PXDN,SERPINE2,TIMP18 Cellular Movementcell movement3.50E-04 of microvascularIL8,TIMP1,TIMP2 endothelial3 cells Cardiovascularcell movementSystem3.50E-04 Development of microvascularIL8,TIMP1,TIMP2 and Function endothelial3 cells Ophthalmic dryDisease eye 3.94E-04 IL6,IL8 2 Cellular Movementcell movement4.00E-04 of naturalCCL5,CXCL10,IL8 killer cells3 Hematologicalcell Systemmovement 4.00E-04Development of naturalCCL5,CXCL10,IL8 killerand Function cells3 Immune Cellcell Trafficking movement4.00E-04 of naturalCCL5,CXCL10,IL8 killer cells3 Cellular Growthinhibition and Proliferationof 4.00E-04cells IL6,ITGA5,PTGER43 Cancer multiple myeloma4.13E-04 EPSTI1,FAM46C,IFIT2,IFIT3,SOD25 Hematologicalmultiple Disease myeloma4.13E-04 EPSTI1,FAM46C,IFIT2,IFIT3,SOD25 Immunologicalmultiple Disease myeloma4.13E-04 EPSTI1,FAM46C,IFIT2,IFIT3,SOD25 Cellular Growthproliferation and Proliferation4.33E-04 of fibroblastsIL6,ITGA5,SFRP1,SOD2,SPRY25 Cellular Developmentproliferation4.33E-04 of fibroblastsIL6,ITGA5,SFRP1,SOD2,SPRY25 Connective proliferationTissue Development4.33E-04 of fibroblasts andIL6,ITGA5,SFRP1,SOD2,SPRY2 Function5 Infectious Diseasereplication of4.40E-04 virus BST2,CCL5,DDX58,IFIT1,IFITM1,IL6,IL8,MX2,OASL,RSAD2,SPRY211 Tissue Developmentdevelopment4.56E-04 of epithelialAXL,CDH2,CXCL10,IL8,PTPRM,TIMP1,TIMP2 tissue 7 Cancer prostatic carcinoma4.72E-04 ANTXR2,IDO1,IL6,KLF6,LPAR1,PODXL,RUNX3,SOD28 Reproductiveprostatic System carcinoma Disease4.72E-04 ANTXR2,IDO1,IL6,KLF6,LPAR1,PODXL,RUNX3,SOD28 Cellular Movementcell movement4.74E-04 of carcinomaCTGF,IL8,ITGA5,NOV,PODXL cell lines5 Cardiovasculardevelopment System4.78E-04 Development of blood vesselAXL,CDH2,CXCL10,IL6,IL8,PTPRM,SLIT2,TGFBR3,TIMP2 and Function9 Organismaldevelopment Development4.78E-04 of blood vesselAXL,CDH2,CXCL10,IL6,IL8,PTPRM,SLIT2,TGFBR3,TIMP29 Cellular Movementcell movement4.95E-04 of phagocytesCCL5,CXCL10,IL6,IL8,SLIT2,TIMP1,TIMP27 Inflammatorycell Response movement4.95E-04 of phagocytesCCL5,CXCL10,IL6,IL8,SLIT2,TIMP1,TIMP27 Hematologicalcell Systemmovement 4.95E-04Development of phagocytesCCL5,CXCL10,IL6,IL8,SLIT2,TIMP1,TIMP2 and Function7 Immune Cellcell Trafficking movement4.95E-04 of phagocytesCCL5,CXCL10,IL6,IL8,SLIT2,TIMP1,TIMP27 Cell Death andcell deathSurvival of5.15E-04 macrophagesCCL5,PMAIP1,SOD23 Cellular Movementchemotaxis5.79E-04 of eosinophilsCCL5,CXCL10,IL83 Inflammatorychemotaxis Response5.79E-04 of eosinophilsCCL5,CXCL10,IL83 Hematologicalchemotaxis System 5.79E-04 Developmentof eosinophilsCCL5,CXCL10,IL8 and Function3 Immune Cellchemotaxis Trafficking5.79E-04 of eosinophilsCCL5,CXCL10,IL83 Hypersensitivitychemotaxis Response5.79E-04 of eosinophilsCCL5,CXCL10,IL83 Cellular Movementchemotaxis5.79E-04 of kidney cellCCL5,CXCL10,IL8 lines 3 Renal and Urologicalchemotaxis System5.79E-04 of kidney Development cellCCL5,CXCL10,IL8 lines and3 Function Inflammatoryaccumulation Response5.89E-04 of granulocytesCCL5,IL8 2 Hematologicalaccumulation System 5.89E-04Development of granulocytesCCL5,IL8 and Function2 Immune Cellaccumulation Trafficking5.89E-04 of granulocytesCCL5,IL8 2 Tissue Developmentaccumulation5.89E-04 of granulocytesCCL5,IL8 2 InflammatoryMultiple Disease Sclerosis5.92E-04 AXL,EPSTI1,IFIT1,IL7R,IRF7,RSAD26 NeurologicalMultiple Disease Sclerosis5.92E-04 AXL,EPSTI1,IFIT1,IL7R,IRF7,RSAD26 Skeletal andMultiple Muscular Sclerosis Disorders5.92E-04 AXL,EPSTI1,IFIT1,IL7R,IRF7,RSAD26 Cellular Movementmigration of5.92E-04 mononuclearCCL5,CXCL10,IL8,ITGA5,TIMP1,TIMP2 leukocytes6 Hematologicalmigration System of 5.92E-04Development mononuclearCCL5,CXCL10,IL8,ITGA5,TIMP1,TIMP2 andleukocytes Function6 Immune Cellmigration Trafficking of5.92E-04 mononuclearCCL5,CXCL10,IL8,ITGA5,TIMP1,TIMP2 leukocytes6 Cancer chronic leukemia6.32E-04 AXL,CD70,IL6,IL8,ITGA5,PXDN6 Hematologicalchronic Disease leukemia6.32E-04 AXL,CD70,IL6,IL8,ITGA5,PXDN6 Cancer squamous cell6.46E-04 tumor CTGF,GAS1,IFIT1,IL6,SFRP1,SLIT2,SOD2,TIMP18 Cellular Growthformation and Proliferation of6.49E-04 connectiveIL6,IL7R,ITGA5 tissue cells3 Cancer clear-cell adenocarcinoma7.23E-04 CA9,SFRP1,TIMP1,TIMP24 Renal and Urologicalclear-cell adenocarcinomaDisease7.23E-04 CA9,SFRP1,TIMP1,TIMP24 Cellular Developmentmorphogenesis7.23E-04 of neuritesIL6,PTPRM,SLIT23 Cell Morphologymorphogenesis7.23E-04 of neuritesIL6,PTPRM,SLIT23 Tissue Developmentmorphogenesis7.23E-04 of neuritesIL6,PTPRM,SLIT23 Cellular Assemblymorphogenesis and 7.23E-04Organization of neuritesIL6,PTPRM,SLIT23 Cellular Functionmorphogenesis and Maintenance7.23E-04 of neuritesIL6,PTPRM,SLIT23 Nervous Systemmorphogenesis Development7.23E-04 of neurites andIL6,PTPRM,SLIT2 Function 3 Cancer chronic B-cell7.56E-04 leukemiaCD70,IL6,IL8,ITGA5,PXDN5 Hematologicalchronic Disease B-cell7.56E-04 leukemiaCD70,IL6,IL8,ITGA5,PXDN5 Immunologicalchronic Disease B-cell7.56E-04 leukemiaCD70,IL6,IL8,ITGA5,PXDN5 Gastrointestinalalcoholic Disease hepatitis8.03E-04 CXCL10,IL6,IL83 Inflammatoryalcoholic Disease hepatitis8.03E-04 CXCL10,IL6,IL83 Hepatic Systemalcoholic Disease hepatitis8.03E-04 CXCL10,IL6,IL83 Cellular Movementchemoattraction8.21E-04 of mononuclearCCL5,IL8 leukocytes2 Inflammatorychemoattraction Response8.21E-04 of mononuclearCCL5,IL8 leukocytes2 Hematologicalchemoattraction System 8.21E-04Development of mononuclearCCL5,IL8 and Function leukocytes2 Immune Cellchemoattraction Trafficking8.21E-04 of mononuclearCCL5,IL8 leukocytes2 Cell-To-Cellchemoattraction Signaling and8.21E-04 Interaction of mononuclearCCL5,IL8 leukocytes2 Cellular Movementchemotaxis8.21E-04 of germ cellCCL5,IL8 tumor cell 2lines Cellular Growthstimulation and Proliferation of8.21E-04 hepatomaCCL5,IL6 cell lines 2 Cell-To-Cellstimulation Signaling andof8.21E-04 hepatoma InteractionCCL5,IL6 cell lines 2 Molecular Transporttranslocation8.21E-04 of proteinCDA,SOD22 Protein Traffickingtranslocation8.21E-04 of proteinCDA,SOD22 Cancer tumorigenesis8.21E-04 of brain cancerKLF6,SOD2 cell lines2 Neurologicaltumorigenesis Disease 8.21E-04 of brain cancerKLF6,SOD2 cell lines2 Cellular Growthproliferation and Proliferation8.30E-04 of breast cancerCA9,CTGF,FRMD6,IL6,ITGA5,PTPRE,RUNX3,SOD2,TIMP2 cell lines9 Cellular Developmentproliferation8.30E-04 of breast cancerCA9,CTGF,FRMD6,IL6,ITGA5,PTPRE,RUNX3,SOD2,TIMP2 cell lines9 Cellular Growthproliferation and Proliferation8.59E-04 of endothelialAXL,CDH2,CXCL10,IL8,PTPRM,TIMP2 cells 6 Cellular Developmentproliferation8.59E-04 of endothelialAXL,CDH2,CXCL10,IL8,PTPRM,TIMP2 cells 6 Tissue Developmentproliferation8.59E-04 of endothelialAXL,CDH2,CXCL10,IL8,PTPRM,TIMP2 cells 6 Cardiovascularproliferation System8.59E-04 Developmentof endothelialAXL,CDH2,CXCL10,IL8,PTPRM,TIMP2 andcells Function6 Organismalproliferation Development8.59E-04 of endothelialAXL,CDH2,CXCL10,IL8,PTPRM,TIMP2 cells 6 Cancer metastatic colorectal8.85E-04 cancerCDH2,CTGF,IL6,MAFB,MSX1,TGFBR36 Gastrointestinalmetastatic Disease colorectal8.85E-04 cancerCDH2,CTGF,IL6,MAFB,MSX1,TGFBR36 Cellular Movementmigration of8.88E-04 fibrosarcomaCDH2,SOD2,TIMP2 cell lines3 Cell Death andapoptosis Survival of9.08E-04 phagocytesCCL5,IL6,IL8,SOD24 Cell Death andcell deathSurvival of9.08E-04 vascular endothelialAXL,IL32,IL8,PMAIP1 cells4 Cell Death andapoptosis Survival of9.12E-04 leukocytesCCL5,CD70,IL6,IL7R,IL8,SOD26 Cardiovascularvasculogenesis System9.24E-04 DevelopmentAXL,CDH2,CXCL10,IL8,PTPRM,SLIT2,TGFBR3,TIMP2 and Function8 Organismalvasculogenesis Development9.24E-04 AXL,CDH2,CXCL10,IL8,PTPRM,SLIT2,TGFBR3,TIMP28 Cellular Developmentdifferentiation9.79E-04 of B lymphocytesCD70,IL6,SFRP13 Hematologicaldifferentiation System 9.79E-04Development of B lymphocytesCD70,IL6,SFRP1 and Function3 Hematopoiesisdifferentiation9.79E-04 of B lymphocytesCD70,IL6,SFRP13 Humoral Immunedifferentiation Response9.79E-04 of B lymphocytesCD70,IL6,SFRP13 Post-Translationaltetramerization Modification9.79E-04 of proteinCCL5,CDA,SOD23 Protein Synthesistetramerization9.79E-04 of proteinCCL5,CDA,SOD23 Cellular Movementcell movement9.81E-04 of leukocytesCCL5,CXCL10,IL6,IL8,ITGA5,SLIT2,TIMP1,TIMP28 Hematologicalcell Systemmovement 9.81E-04Development of leukocytesCCL5,CXCL10,IL6,IL8,ITGA5,SLIT2,TIMP1,TIMP2 and Function8 Immune Cellcell Trafficking movement9.81E-04 of leukocytesCCL5,CXCL10,IL6,IL8,ITGA5,SLIT2,TIMP1,TIMP28 Connective DupuytrenTissue Disorders contracture1.07E-03 COL6A1,COL6A2,TIMP1,TIMP24 Cell Death andapoptosis Survival of1.07E-03 myeloid cellsCCL5,IL6,IL8,SOD24 Hematologicalbinding System of granulocytes 1.08E-03DevelopmentCCL5,CXCL10,IL8 and Function3 Immune Cellbinding Trafficking of granulocytes1.08E-03 CCL5,CXCL10,IL83 Cell-To-Cellbinding Signaling of granulocytesand1.08E-03 InteractionCCL5,CXCL10,IL83 Tissue Developmentbinding of granulocytes1.08E-03 CCL5,CXCL10,IL83 Cellular Developmentdifferentiation1.09E-03 of rhabdomyosarcomaCTGF,NOV2 cell lines Molecular Transportquantity of superoxide1.09E-03 IL8,SOD2 2 Free Radicalquantity Scavenging of superoxide1.09E-03 IL8,SOD2 2 Cancer transitional-cell1.18E-03 carcinomaSFRP1,TIMP1,TIMP23 Renal and Urologicaltransitional-cell Disease1.18E-03 carcinomaSFRP1,TIMP1,TIMP23 Infectious Diseasedengue fever1.29E-03 CCL5,IL6,IL83 Cellular Movementtransmigration1.29E-03 of mononuclearCCL5,IL8,TIMP2 leukocytes3 Hematologicaltransmigration System 1.29E-03Development of mononuclearCCL5,IL8,TIMP2 and Function leukocytes3 Immune Celltransmigration Trafficking1.29E-03 of mononuclearCCL5,IL8,TIMP2 leukocytes3 Cellular Movementmigration of1.31E-03 brain cancerAXL,CDH2,LPAR1,PTPRM cell lines4 Inflammatoryarthritis Disease 1.35E-03 ALPK2,CCL5,CD70,CDA,COL6A1,CXCL10,IL6,IL7R,IL8,ITGA5,PRDM1,RUNX3,SAMD9L,SOD2,TIMP115 Skeletal andarthritis Muscular Disorders1.35E-03 ALPK2,CCL5,CD70,CDA,COL6A1,CXCL10,IL6,IL7R,IL8,ITGA5,PRDM1,RUNX3,SAMD9L,SOD2,TIMP115 Connective arthritisTissue Disorders1.35E-03 ALPK2,CCL5,CD70,CDA,COL6A1,CXCL10,IL6,IL7R,IL8,ITGA5,PRDM1,RUNX3,SAMD9L,SOD2,TIMP115 Gastrointestinalviral hepatitisDisease1.38E-03 CCL5,IL6,IL8,TIMP14 Inflammatoryviral Disease hepatitis1.38E-03 CCL5,IL6,IL8,TIMP14 Infectious Diseaseviral hepatitis1.38E-03 CCL5,IL6,IL8,TIMP14 Hepatic Systemviral hepatitisDisease1.38E-03 CCL5,IL6,IL8,TIMP14 Cell-To-Cellbinding Signaling of cellsand1.39E-03 InteractionAXL,CCL5,CXCL10,FERMT2,IL6,IL8,ITGA5,PTPRM8 Cell-To-Cellactivation Signaling of and1.40E-03 osteoclasts InteractionIL32,IL6 2 Tissue Developmentactivation of1.40E-03 osteoclastsIL32,IL6 2 Embryonic Developmentactivation of1.40E-03 osteoclastsIL32,IL6 2 Connective activationTissue Development of1.40E-03 osteoclasts andIL32,IL6 Function2 Organismalactivation Development of1.40E-03 osteoclastsIL32,IL6 2 Organ Developmentactivation of1.40E-03 osteoclastsIL32,IL6 2 Skeletal andactivation Muscular of System1.40E-03 osteoclasts DevelopmentIL32,IL6 and2 Function Cellular Movementchemoattraction1.40E-03 of granulocytesCCL5,IL8 2 Inflammatorychemoattraction Response1.40E-03 of granulocytesCCL5,IL8 2 Hematologicalchemoattraction System 1.40E-03Development of granulocytesCCL5,IL8 and Function2 Immune Cellchemoattraction Trafficking1.40E-03 of granulocytesCCL5,IL8 2 Cell-To-Cellchemoattraction Signaling and1.40E-03 Interaction of granulocytesCCL5,IL8 2 Cellular Movementmigration of1.40E-03 mesangial CTGF,CXCL10cells 2 Renal and Urologicalmigration ofSystem1.40E-03 mesangial Development CTGF,CXCL10cells and2 Function Cellular Movementmigration of1.40E-03 dendritic cellsCCL5,CXCL10,TIMP13 Inflammatorymigration Response of1.40E-03 dendritic cellsCCL5,CXCL10,TIMP13 Hematologicalmigration System of 1.40E-03Development dendritic cellsCCL5,CXCL10,TIMP1 and Function3 Immune Cellmigration Trafficking of1.40E-03 dendritic cellsCCL5,CXCL10,TIMP13 Cellular MovementLymphocyte1.42E-03 migration CCL5,CXCL10,IL8,ITGA5,TIMP15 HematologicalLymphocyte System 1.42E-03Development migration CCL5,CXCL10,IL8,ITGA5,TIMP1 and Function5 Immune CellLymphocyte Trafficking1.42E-03 migration CCL5,CXCL10,IL8,ITGA5,TIMP15 Cell Morphologycell spreading1.42E-03 CCL5,IL8,ITGA5,PODXL,SPRY25 Cell Cycle mitogenesis1.45E-03 AXL,CXCL10,IL6,SPRY24 Cellular Developmentdifferentiation1.47E-03 of mononuclearCD70,IL6,IL8,IRF7,SFRP1 leukocytes5 Hematologicaldifferentiation System 1.47E-03Development of mononuclearCD70,IL6,IL8,IRF7,SFRP1 and Functionleukocytes5 Hematopoiesisdifferentiation1.47E-03 of mononuclearCD70,IL6,IL8,IRF7,SFRP1 leukocytes5 Cancer lung tumor 1.50E-03 CA9,CDA,GAS1,IL6,ITGA5,MAFB,SFRP1,SLIT2,SOD2,TGFBR3,TIMP111 Respiratorylung Disease tumor 1.50E-03 CA9,CDA,GAS1,IL6,ITGA5,MAFB,SFRP1,SLIT2,SOD2,TGFBR3,TIMP111 Gastrointestinalchronic Disease hepatitis1.52E-03 CCL5,IL6,IL8,TIMP14 Inflammatorychronic Disease hepatitis1.52E-03 CCL5,IL6,IL8,TIMP14 Hepatic Systemchronic Disease hepatitis1.52E-03 CCL5,IL6,IL8,TIMP14 Cellular Developmentdifferentiation1.58E-03 of leukocytesCD70,IL6,IL8,IRF7,PRDM1,SFRP16 Hematologicaldifferentiation System 1.58E-03Development of leukocytesCD70,IL6,IL8,IRF7,PRDM1,SFRP1 and Function6 Hematopoiesisdifferentiation1.58E-03 of leukocytesCD70,IL6,IL8,IRF7,PRDM1,SFRP16 Hematologicalaggregation System 1.59E-03Development of blood cellsCXCL10,IL6,SERPINE2,TIMP2 and Function4 Tissue Developmentaggregation1.59E-03 of blood cellsCXCL10,IL6,SERPINE2,TIMP24 Cellular Movementcell movement1.71E-03 of endothelialAXL,CDH2,IL8,SLIT2,TIMP1,TIMP2 cells 6 Cardiovascularcell movementSystem1.71E-03 Development of endothelialAXL,CDH2,IL8,SLIT2,TIMP1,TIMP2 and cells Function6 Gene Expressionbinding of interferon-stimulated1.74E-03 DDX58,PRDM1 response2 element Cellular Growthproliferation and Proliferation1.74E-03 of sarcomaEMILIN2,SPRY2 cell lines 2 Cellular Developmentproliferation1.74E-03 of sarcomaEMILIN2,SPRY2 cell lines 2 Hematologicalshape System change 1.74E-03Development of basophilsCCL5,IL8 and Function2 Cell Morphologyshape change1.74E-03 of basophilsCCL5,IL8 2 Hypersensitivityshape Response change1.74E-03 of basophilsCCL5,IL8 2 Cell Death andcell deathSurvival of1.74E-03 immune cellsCCL5,CD70,IL6,IL7R,IL8,PMAIP1,SOD27 Cancer brain tumor1.79E-03 ADAM19,EMP3,IL32,LPAR1,SLIT2,TIMP16 Neurologicalbrain Disease tumor1.79E-03 ADAM19,EMP3,IL32,LPAR1,SLIT2,TIMP16 Cancer carcinoma in1.86E-03 lung CA9,CDA,GAS1,IL6,ITGA5,MAFB,SLIT2,TGFBR3,TIMP19 Respiratorycarcinoma Disease in1.86E-03 lung CA9,CDA,GAS1,IL6,ITGA5,MAFB,SLIT2,TGFBR3,TIMP19 Neurologicalprogressive Disease 1.86E-03 motor neuropathyAXL,EPSTI1,IFIT1,IL6,IL7R,IRF7,MAP1B,RSAD2,SOD29 Cell Death andcell viabilitySurvival 1.89E-03of tumor cellALPK2,AXL,CA9,CDH2,CTGF,IL6,IL8,NOV,PTPRE,PTPRM,SOD2,TIMP2 lines 12 Cellular Movementcell movement1.90E-03 of granulocytesCCL5,CXCL10,IL6,IL8,SLIT25 Hematologicalcell Systemmovement 1.90E-03Development of granulocytesCCL5,CXCL10,IL6,IL8,SLIT2 and Function5 Immune Cellcell Trafficking movement1.90E-03 of granulocytesCCL5,CXCL10,IL6,IL8,SLIT25 Cancer head and neck1.97E-03 tumor ADAM19,CA9,EMP3,IL32,IL6,IL8,ITGA5,KLF6,LPAR1,SLIT2,TIMP111 Cancer hemangioma1.99E-03 LPAR1,SERPINE2,SLIT2,TGFBR34 Gastrointestinalchronic Disease hepatitis2.07E-03 C CCL5,IL6,IL83 Inflammatorychronic Disease hepatitis2.07E-03 C CCL5,IL6,IL83 Infectious Diseasechronic hepatitis2.07E-03 C CCL5,IL6,IL83 Hepatic Systemchronic Disease hepatitis2.07E-03 C CCL5,IL6,IL83 Cellular Growthproliferation and Proliferation2.10E-03 of tumor cellAXL,CA9,CTGF,EMILIN2,FRMD6,IDO1,IL6,IL8,ITGA5,KLF6,NOV,PRDM1,PTGER4,PTPRE,RUNX3,SH2B3,SOD2,SPRY2,TIMP2 lines 19 Cellular Developmentproliferation2.10E-03 of tumor cellAXL,CA9,CTGF,EMILIN2,FRMD6,IDO1,IL6,IL8,ITGA5,KLF6,NOV,PRDM1,PTGER4,PTPRE,RUNX3,SH2B3,SOD2,SPRY2,TIMP2 lines 19 Cellular Movementchemoattraction2.11E-03 of phagocytesCCL5,IL8 2 Inflammatorychemoattraction Response2.11E-03 of phagocytesCCL5,IL8 2 Hematologicalchemoattraction System 2.11E-03Development of phagocytesCCL5,IL8 and Function2 Immune Cellchemoattraction Trafficking2.11E-03 of phagocytesCCL5,IL8 2 Cell-To-Cellchemoattraction Signaling and2.11E-03 Interaction of phagocytesCCL5,IL8 2 Cellular Assemblypermeability and 2.11E-03Organization of cellular IL8,PMAIP1membrane 2 Cellular Functionpermeability and Maintenance2.11E-03 of cellular IL8,PMAIP1membrane 2 Cancer squamous-cell2.14E-03 carcinomaCTGF,GAS1,IFIT1,IL6,SFRP1,SLIT2,TIMP17 Cellular Functionengulfment and Maintenance 2.22E-03of cells AXL,CCL5,CXCL10,IL6,IRF75 Inflammatorypolyarticular Disease 2.27E-03 juvenile rheumatoidCCL5,CDA,IL6,PRDM1 arthritis4 Skeletal andpolyarticular Muscular Disorders2.27E-03 juvenile rheumatoidCCL5,CDA,IL6,PRDM1 arthritis4 Immunologicalpolyarticular Disease2.27E-03 juvenile rheumatoidCCL5,CDA,IL6,PRDM1 arthritis4 Connective polyarticularTissue Disorders2.27E-03 juvenile rheumatoidCCL5,CDA,IL6,PRDM1 arthritis4 Infectious Diseasereplication of2.36E-03 HIV-1 BST2,CCL5,IL6,IL84 Cell-To-Celladhesion Signaling of and2.38E-03 connective InteractionCDH2,CTGF,ITGA5 tissue cells3 Tissue Developmentadhesion of2.38E-03 connectiveCDH2,CTGF,ITGA5 tissue cells3 Infectious Diseasedengue shock2.53E-03 syndromeIL6,IL8 2 Cellular Developmentdifferentiation2.53E-03 of plasmaCD70,IL6 cells 2 Hematologicaldifferentiation System 2.53E-03Development of plasmaCD70,IL6 cells and Function2 Hematopoiesisdifferentiation2.53E-03 of plasmaCD70,IL6 cells 2 Humoral Immunedifferentiation Response2.53E-03 of plasmaCD70,IL6 cells 2 Cellular Movementinvasion of bladder2.53E-03 cancerCDH2,SOD2 cell lines2 Cellular Movementmovement of2.56E-03 vascular endothelialIL8,SLIT2,TIMP1,TIMP2 cells4 Cardiovascularmovement System of2.56E-03 Development vascular endothelialIL8,SLIT2,TIMP1,TIMP2 and Function cells4 Cellular Movementcell movement2.57E-03 of myeloidCCL5,CXCL10,IL6,IL8,SLIT2,TIMP2 cells 6 Hematologicalcell Systemmovement 2.57E-03Development of myeloidCCL5,CXCL10,IL6,IL8,SLIT2,TIMP2 andcells Function6 Immune Cellcell Trafficking movement2.57E-03 of myeloidCCL5,CXCL10,IL6,IL8,SLIT2,TIMP2 cells 6 Organismalorganismal Survival 2.88E-03death CXCL10,IL6,IL8,SLIT2,TIMP1,TIMP26 Cancer leiomyomatosis2.96E-03 CTGF,GNG11,IFIT1,IFIT3,NOV,SFRP1,SOD27 Cellular Movementchemotaxis2.97E-03 of endothelialCXCL10,IL8 cell lines2 Cardiovascularchemotaxis System2.97E-03 ofDevelopment endothelialCXCL10,IL8 celland linesFunction2 Cellular Growthcolony and formation Proliferation2.97E-03 of granulocytesCDA,IL6 2 Hematologicalcolony System formation 2.97E-03Development of granulocytesCDA,IL6 and Function2 Hematopoiesiscolony formation2.97E-03 of granulocytesCDA,IL6 2 Cellular Compromiseinjury of cells2.97E-03 IL6,SOD2 2 Cellular Growthproduction and Proliferation of2.97E-03 cells CCL5,IL6 2 Cellular Functionproduction and Maintenance of2.97E-03 cells CCL5,IL6 2 Reproductiveendometriosis System Disease2.98E-03 COL6A1,COL6A2,CTGF,CXCL10,IL6,IL8,SLC2A3,SPRY2,TIMP29 Cellular Growthproliferation and Proliferation3.00E-03 of muscle cellsCCL5,IL6,IL8,ITGA54 Cellular Developmentproliferation3.00E-03 of muscle cellsCCL5,IL6,IL8,ITGA54 Skeletal andproliferation Muscular System3.00E-03 of muscle Development cellsCCL5,IL6,IL8,ITGA5 and4 Function Respiratorydamage Disease of lung3.09E-03 IL6,IL8,TIMP23 Organismaldamage Injury and of Abnormalitieslung3.09E-03 IL6,IL8,TIMP23 Cancer mucoepidermoid3.09E-03 carcinomaIL6,KLF6,TIMP13 Gastrointestinalmucoepidermoid Disease3.09E-03 carcinomaIL6,KLF6,TIMP13 Cancer non-small cell3.13E-03 lung cancerCA9,CDA,ITGA5,MAFB,SLIT2,TGFBR3,TIMP17 Respiratorynon-small Disease cell3.13E-03 lung cancerCA9,CDA,ITGA5,MAFB,SLIT2,TGFBR3,TIMP17 Cellular Developmentdifferentiation3.28E-03 of macrophagesIL6,IRF7,PRDM13 Hematologicaldifferentiation System 3.28E-03Development of macrophagesIL6,IRF7,PRDM1 and Function3 Hematopoiesisdifferentiation3.28E-03 of macrophagesIL6,IRF7,PRDM13 Cancer head and neck3.29E-03 cancer CA9,EMP3,IL32,IL6,IL8,ITGA5,KLF6,LPAR1,SLIT2,TIMP110 Dermatologicalchronic Diseases large3.45E-03 plaqueand Conditions psoriasisCXCL10,IL82 Dermatologicalchronic Diseases small3.45E-03 plaqueand Conditions psoriasisCXCL10,IL82 Cellular Growthinhibition and Proliferationof 3.45E-03mononuclearITGA5,PTGER4 leukocytes2 Hematologicalinhibition System of 3.45E-03DevelopmentmononuclearITGA5,PTGER4 andleukocytes Function2 Cellular Growthproliferation and Proliferation3.50E-03 of lymphocytesCCL5,CD70,IDO1,IL6,IL7R,ITGA56 Cellular Developmentproliferation3.50E-03 of lymphocytesCCL5,CD70,IDO1,IL6,IL7R,ITGA56 Hematologicalproliferation System 3.50E-03Development of lymphocytesCCL5,CD70,IDO1,IL6,IL7R,ITGA5 and Function6 Cellular Movementchemotaxis3.62E-03 of granulocytesCCL5,CXCL10,IL8,SLIT24 Inflammatorychemotaxis Response3.62E-03 of granulocytesCCL5,CXCL10,IL8,SLIT24 Hematologicalchemotaxis System 3.62E-03 Developmentof granulocytesCCL5,CXCL10,IL8,SLIT2 and Function4 Immune Cellchemotaxis Trafficking3.62E-03 of granulocytesCCL5,CXCL10,IL8,SLIT24 Cellular Growthformation and Proliferation of3.62E-03 cells IL6,IL7R,IL8,ITGA54 Cancer endocrine gland3.62E-03 tumor AXL,CDH2,IDO1,IFITM1,IL6,ITGA5,PXDN,SERPINE2,TIMP19 Cell Death andapoptosis Survival of3.68E-03 tumor cell CTGF,DDX58,EMILIN2,IDO1,IL32,IL6,IL8,KLF6,MSX1,PMAIP1,PRDM1,RUNX3,SFRP1,SOD2,SPRY2,TGFBR3lines 16 Inflammatoryinnate Response immune3.70E-03 responseBST2,DDX58,IRF73 Infectious Diseasereplication of3.72E-03 RNA virusBST2,CCL5,DDX58,IFIT1,IFITM1,IL6,IL8,OASL,RSAD29 Cell Death andcell deathSurvival of3.79E-03 cancer cellsIL6,IL8,LPAR1,PMAIP1,SFRP15 Tumor Morphologycell death of3.79E-03 cancer cellsIL6,IL8,LPAR1,PMAIP1,SFRP15 Cellular Movementcell movement3.89E-03 of neutrophilsCCL5,IL6,IL8,SLIT24 Inflammatorycell Response movement3.89E-03 of neutrophilsCCL5,IL6,IL8,SLIT24 Hematologicalcell Systemmovement 3.89E-03Development of neutrophilsCCL5,IL6,IL8,SLIT2 and Function4 Immune Cellcell Trafficking movement3.89E-03 of neutrophilsCCL5,IL6,IL8,SLIT24 Cellular Movementchemotaxis3.97E-03 of mast cellsCCL5,IL8 2 Inflammatorychemotaxis Response3.97E-03 of mast cellsCCL5,IL8 2 Hematologicalchemotaxis System 3.97E-03 Developmentof mast cellsCCL5,IL8 and Function2 Immune Cellchemotaxis Trafficking3.97E-03 of mast cellsCCL5,IL8 2 Hypersensitivitychemotaxis Response3.97E-03 of mast cellsCCL5,IL8 2 Cancer infection of 3.97E-03carcinoma cellAXL,IFITM1 lines 2 Infectious Diseaseinfection of 3.97E-03carcinoma cellAXL,IFITM1 lines 2 Cancer infection of 3.97E-03lung cancerAXL,IFITM1 cell lines 2 Infectious Diseaseinfection of 3.97E-03lung cancerAXL,IFITM1 cell lines 2 Respiratoryinfection Disease of 3.97E-03lung cancerAXL,IFITM1 cell lines 2 Cell Morphologyshape change4.03E-03 of tumorIL8,ITGA5,PODXL,SPRY2 cell lines 4 Hematologicaladhesion System of 4.10E-03Development immune cellsCCL5,CXCL10,IL6,IL8,ITGA5 and Function5 Immune Celladhesion Trafficking of4.10E-03 immune cellsCCL5,CXCL10,IL6,IL8,ITGA55 Cell-To-Celladhesion Signaling of and4.10E-03 immune Interaction cellsCCL5,CXCL10,IL6,IL8,ITGA55 Tissue Developmentadhesion of4.10E-03 immune cellsCCL5,CXCL10,IL6,IL8,ITGA55 NeurologicalAlzheimer's Disease 4.19E-03 disease CTGF,CXCL10,IL6,IL8,SCG5,SERPINE2,SLC2A3,SOD2,TGFBR3,TIMP110 PsychologicalAlzheimer's Disorders4.19E-03 disease CTGF,CXCL10,IL6,IL8,SCG5,SERPINE2,SLC2A3,SOD2,TGFBR3,TIMP110 Inflammatoryrheumatoid Disease 4.25E-03arthritis ALPK2,CCL5,CD70,CDA,CXCL10,IL6,IL7R,IL8,ITGA5,PRDM1,SAMD9L,TIMP112 Skeletal andrheumatoid Muscular Disorders4.25E-03arthritis ALPK2,CCL5,CD70,CDA,CXCL10,IL6,IL7R,IL8,ITGA5,PRDM1,SAMD9L,TIMP112 Immunologicalrheumatoid Disease 4.25E-03arthritis ALPK2,CCL5,CD70,CDA,CXCL10,IL6,IL7R,IL8,ITGA5,PRDM1,SAMD9L,TIMP112 Connective rheumatoidTissue Disorders 4.25E-03arthritis ALPK2,CCL5,CD70,CDA,CXCL10,IL6,IL7R,IL8,ITGA5,PRDM1,SAMD9L,TIMP112 Infectious DiseaseViral Infection4.29E-03 AXL,BST2,CCL5,DDX58,DDX60L,HIST1H2BD,IFIT1,IFIT2,IFIT3,IFITM1,IL32,IL6,IL8,MX2,OASL,RSAD2,SH2B3,SLC2A3,SPRY2,TIMP1,TIMP221 Inflammatorybinding Response of phagocytes4.37E-03 CCL5,CXCL10,IL83 Hematologicalbinding System of phagocytes 4.37E-03DevelopmentCCL5,CXCL10,IL8 and Function3 Cell-To-Cellbinding Signaling of phagocytesand4.37E-03 InteractionCCL5,CXCL10,IL83 Cell Death andapoptosis Survival of4.52E-03 ovarian cellsCDH2,IL8 2 Cell-To-Cellbinding Signaling of prostateand4.52E-03 Interaction cancerITGA5,PTPRM cell lines2 Cellular Movementchemotaxis4.52E-03 of natural killerCCL5,CXCL10 cells 2 Inflammatorychemotaxis Response4.52E-03 of natural killerCCL5,CXCL10 cells 2 Hematologicalchemotaxis System 4.52E-03 Developmentof natural killerCCL5,CXCL10 and cells Function2 Immune Cellchemotaxis Trafficking4.52E-03 of natural killerCCL5,CXCL10 cells 2 Ophthalmic exfoliationDisease syndrome4.52E-03 TIMP1,TIMP22 Cellular Growthproliferation and Proliferation4.52E-03 of mesangialCXCL10,IL6 cells 2 Cellular Developmentproliferation4.52E-03 of mesangialCXCL10,IL6 cells 2 Renal and Urologicalproliferation System4.52E-03 of mesangial DevelopmentCXCL10,IL6 cells and2 Function Organismalsurvival Survival of organism4.77E-03 CTGF,CXCL10,IL6,SOD24 Cell Death andapoptosis Survival of4.86E-03 pancreaticIL32,IL6,IL8 cancer cell3 lines Cellular Movementchemotaxis4.86E-03 of T lymphocytesCCL5,CXCL10,IL83 Inflammatorychemotaxis Response4.86E-03 of T lymphocytesCCL5,CXCL10,IL83 Hematologicalchemotaxis System 4.86E-03 Developmentof T lymphocytesCCL5,CXCL10,IL8 and Function3 Immune Cellchemotaxis Trafficking4.86E-03 of T lymphocytesCCL5,CXCL10,IL83 Cell-mediatedchemotaxis Immune 4.86E-03Responseof T lymphocytesCCL5,CXCL10,IL83 Cell Death andcell deathSurvival of4.95E-03 tumor cell CDA,CTGF,DDX58,EMILIN2,FRMD6,IDO1,IL32,IL6,IL8,KLF6,MSX1,PMAIP1,PRDM1,RUNX3,SFRP1,SOD2,SPRY2,TGFBR3lines 18 Cell-To-Celladhesion Signaling of and5.12E-03 kidney Interaction cellsIL8,SOD2,TIMP13 Tissue Developmentadhesion of5.12E-03 kidney cellsIL8,SOD2,TIMP13 Renal and Urologicaladhesion ofSystem5.12E-03 kidney Development cellsIL8,SOD2,TIMP1 and3 Function Cellular Developmenttubulation of5.12E-03 endothelialAXL,IL8,SLIT2 cells 3 Cell Morphologytubulation of5.12E-03 endothelialAXL,IL8,SLIT2 cells 3 Tissue Developmenttubulation of5.12E-03 endothelialAXL,IL8,SLIT2 cells 3 Cardiovasculartubulation System of5.12E-03 DevelopmentendothelialAXL,IL8,SLIT2 cells and Function3 Organismaltubulation Development of5.12E-03 endothelialAXL,IL8,SLIT2 cells 3 Cellular Movementmigration of5.39E-03 granulocytesCCL5,IL6,IL83 Hematologicalmigration System of 5.39E-03Development granulocytesCCL5,IL6,IL8 and Function3 Immune Cellmigration Trafficking of5.39E-03 granulocytesCCL5,IL6,IL83 Protein Synthesispolymerization5.61E-03 of proteinCCL5,CDA,PMAIP1,SOD24 Free Radicalmetabolism Scavenging5.66E-03 of hydrogenIL6,PXDN,SOD2 peroxide 3 Small Moleculemetabolism Biochemistry5.66E-03 of hydrogenIL6,PXDN,SOD2 peroxide 3 Cell Morphologypolarization 5.66E-03of cells CCL5,CXCL10,IL83 Post-Translationalhomotetramerization Modification5.71E-03 ofCDA,SOD2 protein 2 Protein Synthesishomotetramerization5.71E-03 ofCDA,SOD2 protein 2 Behavior invasive behavior5.71E-03 IFITM1,NOV2 Cellular Movementmigration of5.71E-03 fibroblast cellCXCL10,ITGA5 lines 2 Connective migrationTissue Development of5.71E-03 fibroblast andcellCXCL10,ITGA5 Functionlines 2 Cellular Movementmigration of5.71E-03 microvascularTIMP1,TIMP2 endothelial2 cells Cardiovascularmigration System of5.71E-03 DevelopmentmicrovascularTIMP1,TIMP2 and endothelial Function2 cells Inflammatorysystemic Disease inflammatory5.71E-03 AXL,IL6response syndrome2 Nutritional Diseaseobesity 5.76E-03 CA9,CCL5,CXCL10,IL6,IL85 Cellular Movementmigration of5.94E-03 cervical cancerAXL,CA9,CDH2 cell lines3 Cellular Growthproliferation and Proliferation5.94E-03 of B lymphocytesCD70,IL6,ITGA53 Cellular Developmentproliferation5.94E-03 of B lymphocytesCD70,IL6,ITGA53 Hematologicalproliferation System 5.94E-03Development of B lymphocytesCD70,IL6,ITGA5 and Function3 Humoral Immuneproliferation Response5.94E-03 of B lymphocytesCD70,IL6,ITGA53 Cellular Movementmigration of6.03E-03 endothelialAXL,IL8,SLIT2,TIMP1,TIMP2 cells 5 Cardiovascularmigration System of6.03E-03 DevelopmentendothelialAXL,IL8,SLIT2,TIMP1,TIMP2 cells and Function5 Embryonic Developmentdevelopment6.23E-03 of body axisMSX1,SFRP1,TIMP23 Organismaldevelopment Development6.23E-03 of body axisMSX1,SFRP1,TIMP23 Cellular Developmentdifferentiation6.23E-03 of red bloodIL6,MAFB,TIMP1 cells 3 Hematologicaldifferentiation System 6.23E-03Development of red bloodIL6,MAFB,TIMP1 and cells Function3 Hematopoiesisdifferentiation6.23E-03 of red bloodIL6,MAFB,TIMP1 cells 3 Cancer tumorigenesis6.23E-03 of tumorIL6,KLF6,SOD2 cell lines 3 Cardiovascularvascular Disease disease6.27E-03 CTGF,IL6,IL8,KLF6,PTGER4,PTPRM,RSAD2,TIMP1,TIMP29 Cardiovasculararterial Disease occlusive6.33E-03 diseaseIL6,KLF6,PTGER4,PTPRM,RSAD2,TIMP1,TIMP27 Infectious DiseaseB cell lymphoproliferative6.35E-03 IL6 disorder 1 ImmunologicalB cell Disease lymphoproliferative6.35E-03 IL6 disorder 1 Cell Cycle G1/S phase6.35E-03 transition ofIL6 myeloma 1cell lines NeurologicalRaine Disease syndrome6.35E-03 FAM20C 1 Skeletal andRaine Muscular syndrome Disorders6.35E-03 FAM20C 1 Connective RaineTissue syndrome Disorders6.35E-03 FAM20C 1 DevelopmentalRaine Disorder syndrome6.35E-03 FAM20C 1 Cell-To-Celladhesion Signaling of and6.35E-03 B lymphoblastoid InteractionIL8 cell lines1 Tissue Developmentadhesion of6.35E-03 B lymphoblastoidIL8 cell lines1 Cell-To-Celladhesion Signaling of and6.35E-03 cord Interaction blood ITGA5cells 1 Tissue Developmentadhesion of6.35E-03 cord blood ITGA5cells 1 Cell-To-Celladhesion Signaling of and6.35E-03 hepatic Interaction stellateCTGF cells 1 Tissue Developmentadhesion of6.35E-03 hepatic stellateCTGF cells 1 Connective adhesionTissue Development of6.35E-03 hepatic stellate andCTGF Function cells 1 Hepatic Systemadhesion Development of6.35E-03 hepatic and stellate CTGFFunction cells 1 Tissue Developmentaggregation6.35E-03 of melanomaCDH2 cells 1 Cellular Compromiseaggregation6.35E-03 of melanomaCDH2 cells 1 Tumor Morphologyaggregation6.35E-03 of melanomaCDH2 cells 1 Tissue Developmentaggregation6.35E-03 of myoblastsITGA5 1 Skeletal andaggregation Muscular System6.35E-03 of myoblasts DevelopmentITGA5 and1 Function Tissue Developmentangiogenesis6.35E-03 of embryonicTIMP2 tissue 1 Embryonic Developmentangiogenesis6.35E-03 of embryonicTIMP2 tissue 1 Cardiovascularangiogenesis System6.35E-03 Development of embryonicTIMP2 and tissue Function1 Organismalangiogenesis Development6.35E-03 of embryonicTIMP2 tissue 1 Cell Cycle arrest in G2/M6.35E-03 phase ofIL6 myeloma cell1 lines Cell-To-Cellattachment Signaling and 6.35E-03of sarcoma InteractionSPRY2 cell lines 1 Tissue Developmentattachment 6.35E-03of sarcomaSPRY2 cell lines 1 Small Moleculebinding Biochemistry of L-amino6.35E-03 acidIDO1 1 Amino Acid bindingMetabolism of L-amino6.35E-03 acidIDO1 1 Small Moleculebinding Biochemistry of aromatic6.35E-03 aminoIDO1 acid 1 Amino Acid bindingMetabolism of aromatic6.35E-03 aminoIDO1 acid 1 Cell-To-Cellbinding Signaling of brainand6.35E-03 Interaction cancer ITGA5cell lines 1 Small Moleculebinding Biochemistry of essential6.35E-03 aminoIDO1 acids 1 Amino Acid bindingMetabolism of essential6.35E-03 aminoIDO1 acids 1 Gene Expressionbinding of sterol6.35E-03 responseIL6 element1 Cell Morphologycell spreading6.35E-03 of carcinomaPODXL cell lines1 Cell Morphologycell spreading6.35E-03 of lung cancerPODXL cell lines1 Cell Morphologycell spreading6.35E-03 of sarcomaSPRY2 cell lines1 Cellular Movementchemoattraction6.35E-03 of mastCCL5 cells 1 Inflammatorychemoattraction Response6.35E-03 of mastCCL5 cells 1 Hematologicalchemoattraction System 6.35E-03Development of mastCCL5 cells and Function1 Immune Cellchemoattraction Trafficking6.35E-03 of mastCCL5 cells 1 Cell-To-Cellchemoattraction Signaling and6.35E-03 Interaction of mastCCL5 cells 1 Hypersensitivitychemoattraction Response6.35E-03 of mastCCL5 cells 1 Cellular Movementchemotaxis6.35E-03 of prostate IL8cancer cell 1lines Cellular Growthclonogenicity and Proliferation6.35E-03 of fibrosarcomaEMILIN2 cell lines1 Free Radicalconversion Scavenging 6.35E-03of hydrogenSOD2 peroxide 1 Small Moleculeconversion Biochemistry 6.35E-03of hydrogenSOD2 peroxide 1 Cellular Growthdelay and in growth Proliferation6.35E-03 of breastCA9 cancer cell1 lines Cellular Developmentdelay in growth6.35E-03 of breastCA9 cancer cell1 lines Cellular Developmentdifferentiation6.35E-03 of B lymphoblastoidIL6 1cell lines Cellular Compromisedisassembly6.35E-03 of actin CTGF 1 Cellular Movementdissemination6.35E-03 of carcinomaCTGF cell lines1 Cellular Movementdissemination6.35E-03 of hepatomaCTGF cell lines1 Dermatologicaledema Diseases of skin6.35E-03 and ConditionsIL8 1 Organismaledema Injury and of skin Abnormalities6.35E-03 IL8 1 Dermatologicalfollicular Diseases hyperkeratosis6.35E-03 and ConditionsIL8 1 Organismalfollicular Injury and hyperkeratosis Abnormalities6.35E-03 IL8 1 Cardiovascularformation System of6.35E-03 Developmentcapillary plexusTGFBR3 and Function1 Organismalformation Development of6.35E-03 capillary plexusTGFBR3 1 Cardiovascularformation System of6.35E-03 Developmentvascular sproutIL8 and Function1 Cellular Movementhaptotaxis of6.35E-03 leukocyteIL8 cell lines 1 Hematologicalhaptotaxis System of 6.35E-03Development leukocyteIL8 cell and lines Function1 Immune Cellhaptotaxis Trafficking of6.35E-03 leukocyteIL8 cell lines 1 Cell Morphologyheight of colon6.35E-03 cancer cellBST2 lines 1 Dermatologicalhypoplastic Diseases 6.35E-03enamel-onycholysis-hypohidrosis and ConditionsMSX1 1 syndrome Hereditary Disorderhypoplastic 6.35E-03enamel-onycholysis-hypohidrosisMSX1 1 syndrome Organismalhypoplastic Injury and Abnormalities6.35E-03enamel-onycholysis-hypohidrosisMSX1 1 syndrome Developmentalhypoplastic Disorder 6.35E-03enamel-onycholysis-hypohidrosisMSX1 1 syndrome Small Moleculeinactivation Biochemistry 6.35E-03of cytarabineCDA 1 Drug Metabolisminactivation 6.35E-03of cytarabineCDA 1 Nucleic Acidinactivation Metabolism 6.35E-03of cytarabineCDA 1 Reproductiveinfantile System systemic Disease6.35E-03 hyalinosisANTXR2 1 Cardiovascularinfantile Disease systemic6.35E-03 hyalinosisANTXR2 1 Connective infantileTissue Disorders systemic6.35E-03 hyalinosisANTXR2 1 Cellular Growthinhibition and Proliferationof 6.35E-03Th17 cells PTGER4 1 Hematologicalinhibition System of 6.35E-03DevelopmentTh17 cells PTGER4 and Function1 Cellular Growthinhibition and Proliferationof 6.35E-03hepatoma cellIL6 lines 1 Embryonic Developmentinjury of embryonic6.35E-03 cell SOD2lines 1 Cellular Compromiseinjury of embryonic6.35E-03 cell SOD2lines 1 Cellular Compromiseinjury of epithelial6.35E-03 cell linesSOD2 1 Cancer juvenile hyaline6.35E-03 fibromatosisANTXR2 1 Hereditary Disorderjuvenile hyaline6.35E-03 fibromatosisANTXR2 1 Small Moleculemetabolism Biochemistry6.35E-03 of L-tryptophanIDO1 1 Amino Acid metabolismMetabolism6.35E-03 of L-tryptophanIDO1 1 Small Moleculemetabolism Biochemistry6.35E-03 of cytosineCDA 1 Nucleic Acidmetabolism Metabolism6.35E-03 of cytosineCDA 1 Cardiovascularmineralization Disease6.35E-03 of calcifyingIL6 vascular1 cells Cell Morphologymineralization6.35E-03 of calcifyingIL6 vascular1 cells Skeletal andmyosclerosis Muscular Disorders6.35E-03 myopathyCOL6A2 1 Hereditary Disordermyosclerosis6.35E-03 myopathyCOL6A2 1 Developmentalmyosclerosis Disorder6.35E-03 myopathyCOL6A2 1 Gastrointestinalopisthorchiasis Disease6.35E-03 periductalIL6 fibrosis 1 Infectious Diseaseopisthorchiasis6.35E-03 periductalIL6 fibrosis 1 Hepatic Systemopisthorchiasis Disease6.35E-03 periductalIL6 fibrosis 1 Organismalopisthorchiasis Injury and Abnormalities6.35E-03 periductalIL6 fibrosis 1 Cellular Growthoutgrowth and Proliferation of6.35E-03 retinal ganglionSLIT2 cells 1 Cellular Developmentoutgrowth of6.35E-03 retinal ganglionSLIT2 cells 1 Nervous Systemoutgrowth Development of6.35E-03 retinal andganglionSLIT2 Function cells 1 Small Moleculephosphorylation Biochemistry6.35E-03 of dUMPCMPK2 1 Nucleic Acidphosphorylation Metabolism6.35E-03 of dUMPCMPK2 1 Small Moleculephosphorylation Biochemistry6.35E-03 of floxuridineCMPK2 1 Drug Metabolismphosphorylation6.35E-03 of floxuridineCMPK2 1 Nucleic Acidphosphorylation Metabolism6.35E-03 of floxuridineCMPK2 1 Cancer polyploidy of6.35E-03 sarcoma cellSPRY2 lines 1 Cell Cycle polyploidy of6.35E-03 sarcoma cellSPRY2 lines 1 Cell Morphologyprojection of6.35E-03 axons SLIT2 1 Cellular Assemblyprojection and of 6.35E-03Organization axons SLIT2 1 Nervous Systemprojection Development of6.35E-03 axons andSLIT2 Function 1 Cellular Growthproliferation and Proliferation6.35E-03 of tumor-infiltratingIDO1 lymphocytes1 Tissue Morphologyquantity of progenitor6.35E-03 cellsSH2B3 1 Organismalregeneration Development6.35E-03 of foot TIMP1 1 Infectious Diseaserelease of human6.35E-03 herpesvirusBST2 8 1 Molecular Transportsecretion of6.35E-03 glucagon IL6 1 Small Moleculesecretion Biochemistry of6.35E-03 glucagon IL6 1 Drug Metabolismsecretion of6.35E-03 glucagon IL6 1 Cell Morphologyshape of neutrophils6.35E-03 IL8 1 Embryonic Developmentspecification6.35E-03 of dorsal-ventralSFRP1 axis 1 Organismalspecification Development6.35E-03 of dorsal-ventralSFRP1 axis 1 Cancer stimulation of6.35E-03 acute myeloidIL6 leukemia1 blast cells Cellular Growthstimulation and Proliferation of6.35E-03 acute myeloidIL6 leukemia1 blast cells Cell-To-Cellstimulation Signaling andof6.35E-03 acute Interaction myeloidIL6 leukemia1 blast cells Tumor Morphologystimulation of6.35E-03 acute myeloidIL6 leukemia1 blast cells Cellular Movementtransmigration6.35E-03 of Th1 cellsCCL5 1 Hematologicaltransmigration System 6.35E-03Development of Th1 cellsCCL5 and Function1 Immune Celltransmigration Trafficking6.35E-03 of Th1 cellsCCL5 1 Cell-mediatedtransmigration Immune 6.35E-03Response of Th1 cellsCCL5 1 Cellular Developmenttubulogenesis6.35E-03 of endothelialIL8 cell lines1 Embryonic Developmenttubulogenesis6.35E-03 of endothelialIL8 cell lines1 Cardiovasculartubulogenesis System6.35E-03 Development of endothelialIL8 and cell Function lines1 Organismaltubulogenesis Development6.35E-03 of endothelialIL8 cell lines1 Cancer tumorigenesis6.35E-03 of kidneyIL6 cells 1 Renal and Urologicaltumorigenesis Disease6.35E-03 of kidneyIL6 cells 1 Cell Death andapoptosis Survival of6.36E-03 chronic lymphocyticIL6,LPAR1 leukemia2 cells Tumor Morphologyapoptosis of6.36E-03 chronic lymphocyticIL6,LPAR1 leukemia2 cells Inflammatorybinding Response of neutrophils6.36E-03 CXCL10,IL82 Hematologicalbinding System of neutrophils 6.36E-03DevelopmentCXCL10,IL8 and Function2 Immune Cellbinding Trafficking of neutrophils6.36E-03 CXCL10,IL82 Cell-To-Cellbinding Signaling of neutrophilsand6.36E-03 InteractionCXCL10,IL82 Tissue Developmentbinding of neutrophils6.36E-03 CXCL10,IL82 Cellular Movementmigration of6.36E-03 eosinophilsCCL5,IL8 2 Hematologicalmigration System of 6.36E-03Development eosinophilsCCL5,IL8 and Function2 Immune Cellmigration Trafficking of6.36E-03 eosinophilsCCL5,IL8 2 Hypersensitivitymigration Response of6.36E-03 eosinophilsCCL5,IL8 2 Cellular Movementmigration of6.36E-03 leukocyte cellCCL5,IL8 lines 2 Hematologicalmigration System of 6.36E-03Development leukocyte cellCCL5,IL8 and lines Function2 Immune Cellmigration Trafficking of6.36E-03 leukocyte cellCCL5,IL8 lines 2 Cellular Movementtransmigration6.36E-03 of neutrophilsIL6,IL8 2 Inflammatorytransmigration Response6.36E-03 of neutrophilsIL6,IL8 2 Hematologicaltransmigration System 6.36E-03Development of neutrophilsIL6,IL8 and Function2 Immune Celltransmigration Trafficking6.36E-03 of neutrophilsIL6,IL8 2 Cell Death andcell viabilitySurvival 6.73E-03of breast cancerCA9,CTGF,PTPRE,SOD2 cell lines4 Cancer papillary carcinoma6.73E-03 ITGA5,SFRP1,TIMP1,TIMP24 Cardiovascularabdominal Disease aortic7.04E-03 aneurysmTIMP1,TIMP22 Cellular Movementchemotaxis7.04E-03 of leukocyteCCL5,IL8 cell lines 2 Hematologicalchemotaxis System 7.04E-03 Developmentof leukocyteCCL5,IL8 cell and lines Function2 Immune Cellchemotaxis Trafficking7.04E-03 of leukocyteCCL5,IL8 cell lines 2 Tissue Developmentformation of7.04E-03 tubules LPAR1,SLIT22 Cellular Assemblyformation and of 7.04E-03Organization tubules LPAR1,SLIT22 Cancer brain cancer7.05E-03 EMP3,IL32,LPAR1,SLIT2,TIMP15 Neurologicalbrain Disease cancer7.05E-03 EMP3,IL32,LPAR1,SLIT2,TIMP15 Cellular Growthcolony and formation Proliferation7.15E-03 of cellsCDA,FRMD6,IL6,KLF6,SFRP1,SOD2,SPRY27 Cell-To-Celladhesion Signaling of and7.15E-03 epithelial Interaction cellsITGA5,SOD2,TIMP13 Tissue Developmentadhesion of7.15E-03 epithelial cellsITGA5,SOD2,TIMP13 Cell Death andapoptosis Survival of7.15E-03 myeloma cellIL6,PMAIP1,PRDM1 lines 3 Cell Death andapoptosis Survival of7.15E-03 vascular endothelialAXL,IL8,PMAIP1 cells3 CardiovascularBudd-Chiari Disease7.75E-03 syndrome CTGF,IL6 2 HematologicalBudd-Chiari Disease7.75E-03 syndrome CTGF,IL6 2 Cell Death andapoptosis Survival of7.75E-03 macrophagesCCL5,SOD22 Cellular Growthformation and Proliferation of7.75E-03 osteoclastsIL6,IL7R 2 Connective formationTissue Development of7.75E-03 osteoclasts andIL6,IL7R Function2 Skeletal andformation Muscular of System7.75E-03 osteoclasts DevelopmentIL6,IL7R and2 Function Cellular Movementmigration of7.75E-03 peripheral CCL5,IL8blood leukocytes2 Hematologicalmigration System of 7.75E-03Development peripheral CCL5,IL8blood and leukocytes Function2 Immune Cellmigration Trafficking of7.75E-03 peripheral CCL5,IL8blood leukocytes2 Cellular Movementrecruitment 7.75E-03of leukocytesCCL5,IL8 2 Hematologicalrecruitment System 7.75E-03Developmentof leukocytesCCL5,IL8 and Function2 Immune Cellrecruitment Trafficking 7.75E-03of leukocytesCCL5,IL8 2 Cell-To-Cellrecruitment Signaling and 7.75E-03of leukocytes InteractionCCL5,IL8 2 Tissue Developmentaccumulation7.81E-03 of cells CCL5,IL6,IL83 Hematologicalcoagulation System 7.81E-03 Developmentof blood IL6,IL8,SERPINE2 and Function3 Organismalcoagulation Functions 7.81E-03 of blood IL6,IL8,SERPINE23 Renal and Urologicaldiabetic nephropathy Disease8.00E-03 GAS1,IFIT1,PTGER4,PTPRM4 Infectious Diseaseproduction of8.15E-03 virus BST2,IL32,RSAD23 Gastrointestinalcirrhosis Disease of 8.22E-03liver CTGF,IL7R,IL8,ITGA54 Hepatic Systemcirrhosis Disease of 8.22E-03liver CTGF,IL7R,IL8,ITGA54 Organismalcirrhosis Injury and of Abnormalities8.22E-03liver CTGF,IL7R,IL8,ITGA54 Cellular Developmentdifferentiation8.45E-03 of connectiveIL32,IL6,IL8,SFRP1 tissue 4cells Cellular Movementchemotaxis8.48E-03 of macrophagesCCL5,CXCL102 Inflammatorychemotaxis Response8.48E-03 of macrophagesCCL5,CXCL102 Hematologicalchemotaxis System 8.48E-03 Developmentof macrophagesCCL5,CXCL10 and Function2 Immune Cellchemotaxis Trafficking8.48E-03 of macrophagesCCL5,CXCL102 Neurologicalmild Disease cognitive8.48E-03 impairmentCXCL10,IL82 CardiovascularThrombosis Disease8.50E-03 CTGF,IL6,PTGER43 HematologicalThrombosis Disease8.50E-03 CTGF,IL6,PTGER43 Cell-To-Celladhesion Signaling of and8.85E-03 vascular Interaction endothelialCDH2,FERMT2,IL8 cells3 Tissue Developmentadhesion of8.85E-03 vascular endothelialCDH2,FERMT2,IL8 cells3 Cardiovascularadhesion System of8.85E-03 vascularDevelopment endothelialCDH2,FERMT2,IL8 and Function cells3 Cell Morphologycell spreading8.85E-03 of tumor ITGA5,PODXL,SPRY2cell lines 3 Cell Morphologyoutgrowth of8.85E-03 plasma membraneIL6,SLIT2,TIMP1 projections3 Cellular Assemblyoutgrowth and of 8.85E-03Organization plasma membraneIL6,SLIT2,TIMP1 projections3 Cell Death andcell viabilitySurvival 9.25E-03of hepatomaCDH2,IL6 cell lines 2 Cellular Movementchemotaxis9.25E-03 of embryonicCCL5,CXCL10 cell lines2 Embryonic Developmentchemotaxis9.25E-03 of embryonicCCL5,CXCL10 cell lines2 Cellular Movementchemotaxis9.25E-03 of epithelialCCL5,CXCL10 cell lines 2 Hair and Skinchemotaxis Development9.25E-03 of epithelial and FunctionCCL5,CXCL10 cell lines 2 Cell Death andapoptosis Survival of9.98E-03 epithelial cellsIL8,SFRP1,TIMP13 Cell-To-Cellbinding Signaling of endothelialand9.98E-03 Interaction cellsAXL,CCL5,IL83 Cardiovascularbinding System of endothelial9.98E-03 Development cellsAXL,CCL5,IL8 and Function3 Infectious DiseaseEbola hemorrhagic1.01E-02 feverAXL,IL6 2 HematologicalEbola Disease hemorrhagic1.01E-02 feverAXL,IL6 2 Cancer leukemia 1.02E-02 AXL,CD70,IL6,IL7R,IL8,ITGA5,PXDN7 Hematologicalleukemia Disease1.02E-02 AXL,CD70,IL6,IL7R,IL8,ITGA5,PXDN7 Cell Cycle G1 phase 1.03E-02 IL6,ITGA5,KLF6,MX2,SPRY2,TIMP26 Infectious Diseaseflu 1.04E-02 IFIT1,IFIT2,TIMP13 Cell-To-Cellattachment Signaling and 1.09E-02of tumor Interaction cellITGA5,SPRY2 lines 2 Tissue Developmentattachment 1.09E-02of tumor cellITGA5,SPRY2 lines 2 Inflammatoryquantity Response of phagocytes1.09E-02 IL6,IL8 2 Hematologicalquantity System of phagocytes 1.09E-02DevelopmentIL6,IL8 and Function2 Tissue Morphologyquantity of phagocytes1.09E-02 IL6,IL8 2 Infectious Diseasesevere sepsis1.09E-02 AXL,IL6 2 Cellular Movementchemotaxis1.12E-02 of neutrophilsCCL5,IL8,SLIT23 Inflammatorychemotaxis Response1.12E-02 of neutrophilsCCL5,IL8,SLIT23 Hematologicalchemotaxis System 1.12E-02 Developmentof neutrophilsCCL5,IL8,SLIT2 and Function3 Immune Cellchemotaxis Trafficking1.12E-02 of neutrophilsCCL5,IL8,SLIT23 Cellular Movementcell movement1.16E-02 of lung cancerITGA5,PODXL,SLIT2 cell lines3 Inflammatoryactivation Response of1.17E-02 neutrophilsCCL5,IL8 2 Hematologicalactivation System of 1.17E-02Development neutrophilsCCL5,IL8 and Function2 Immune Cellactivation Trafficking of1.17E-02 neutrophilsCCL5,IL8 2 Cell-To-Cellactivation Signaling of and1.17E-02 neutrophils InteractionCCL5,IL8 2 Cell Death andapoptosis Survival of1.17E-02 kidney cancerIL6,SFRP1 cell lines2 Immunologicalsystemic Disease autoimmune1.18E-02 syndromeALPK2,CCL5,CD70,CDA,CXCL10,IL6,IL7R,IL8,ITGA5,PRDM1,SAMD9L,SH2B3,TIMP113 Cancer carcinoma in1.18E-02 breast CD70,CDH2,IFIT1,LPAR1,PRDM1,PXDN,SLIT27 Cancer salivary duct1.26E-02 carcinomaIL6,TIMP1 2 Gastrointestinalsalivary Disease duct1.26E-02 carcinomaIL6,TIMP1 2 Inflammatoryaccumulation Response1.27E-02 of basophilsCCL5 1 Hematologicalaccumulation System 1.27E-02Development of basophilsCCL5 and Function1 Immune Cellaccumulation Trafficking1.27E-02 of basophilsCCL5 1 Tissue Developmentaccumulation1.27E-02 of basophilsCCL5 1 Hypersensitivityaccumulation Response1.27E-02 of basophilsCCL5 1 Tissue Developmentaccumulation1.27E-02 of myelomaIL6 cell lines1 Cell-To-Cellactivation Signaling of and1.27E-02 breast Interaction cellAXL lines 1 Reproductiveactivation System ofDevelopment1.27E-02 breast cellAXL lines and Function1 Inflammatoryacute Disease disseminated1.27E-02 encephalomyelitisTIMP1 1 Neurologicalacute Disease disseminated1.27E-02 encephalomyelitisTIMP1 1 Cell-To-Celladhesion Signaling of and1.27E-02 bone Interaction marrowITGA5 stromal cells1 Tissue Developmentadhesion of1.27E-02 bone marrowITGA5 stromal cells1 Connective adhesionTissue Development of1.27E-02 bone marrow andITGA5 Functionstromal cells1 Cell-To-Celladhesion Signaling of and1.27E-02 glomerular InteractionIL8 cells 1 Tissue Developmentadhesion of1.27E-02 glomerularIL8 cells 1 Renal and Urologicaladhesion ofSystem1.27E-02 glomerular DevelopmentIL8 cells and1 Function Cellular Movementadhesion of1.27E-02 naive T lymphocytesITGA5 1 Hematologicaladhesion System of 1.27E-02Development naive T lymphocytesITGA5 and Function1 Immune Celladhesion Trafficking of1.27E-02 naive T lymphocytesITGA5 1 Cell-To-Celladhesion Signaling of and1.27E-02 naive Interaction T lymphocytesITGA5 1 Tissue Developmentadhesion of1.27E-02 naive T lymphocytesITGA5 1 Cell-mediatedadhesion Immune of 1.27E-02 Responsenaive T lymphocytesITGA5 1 Cell-To-Celladhesion Signaling of and1.27E-02 rhabdomyosarcoma InteractionNOV cell1 lines Tissue Developmentadhesion of1.27E-02 rhabdomyosarcomaNOV cell1 lines Cancer apoptosis of1.27E-02 basal-cell IL6carcinoma 1 Cell Death andapoptosis Survival of1.27E-02 basal-cell IL6carcinoma 1 Cell Death andapoptosis Survival of1.27E-02 multiple myelomaIL6 cells1 Tumor Morphologyapoptosis of1.27E-02 multiple myelomaIL6 cells1 Cell Death andapoptosis Survival of1.27E-02 sarcoma cellEMILIN2 lines 1 Cell Death andapoptosis Survival of1.27E-02 tumor-infiltratingCCL5 lymphocytes1 Cell Cycle arrest in G0/G11.27E-02 phase transitionIL6 of1 hematopoietic cell lines Cell Cycle arrest in cell1.27E-02 cycle progressionIL6 of B1 lymphoblastoid cell lines Infectious Diseaseattachment 1.27E-02of HIV-1 BST2 1 Cell-To-Cellattachment Signaling and 1.27E-02of breast Interaction cancerITGA5 cell lines1 Tissue Developmentattachment 1.27E-02of breast cancerITGA5 cell lines1 Gene Expressionbinding of LPS/IL11.27E-02 responseIL6 element1 Hematologicalbinding System of Th1 1.27E-02Development cells CCL5 and Function1 Cell-To-Cellbinding Signaling of Th1and1.27E-02 cellsInteractionCCL5 1 Tissue Developmentbinding of Th11.27E-02 cells CCL5 1 Gene Expressionbinding of hSIE1.27E-02 (high-affinityIL6 Sis-inducible1 element) Respiratorybleeding Disease of 1.27E-02lung TIMP2 1 Organismalbleeding Injury and of Abnormalities1.27E-02lung TIMP2 1 Cellular Compromisecalcification1.27E-02 of vascularIL6 smooth muscle1 cells Cell Death andcell viabilitySurvival 1.27E-02of plasma cellsIL6 1 Hematologicalcell Systemviability 1.27E-02Developmentof plasma cellsIL6 and Function1 Cellular Movementchemorepulsion1.27E-02 of axonsSLIT2 1 Cell-To-Cellchemorepulsion Signaling and1.27E-02 Interaction of axonsSLIT2 1 Cellular Assemblychemorepulsion and 1.27E-02Organization of axonsSLIT2 1 Nervous Systemchemorepulsion Development1.27E-02 of axonsandSLIT2 Function 1 Skeletal andcleft Muscular face Disorders1.27E-02 MSX1 1 Connective cleftTissue face Disorders1.27E-02 MSX1 1 Developmentalcleft Disorderface 1.27E-02 MSX1 1 Cellular Growthcolony and formation Proliferation1.27E-02 of lungSOD2 cell lines 1 Cell Death andcolony Survival survival1.27E-02 of breastCA9 cancer cell1 lines Cellular Functioncolony and survival Maintenance1.27E-02 of breastCA9 cancer cell1 lines Cellular Developmentdifferentiation1.27E-02 of B-lymphocyteIL6 derived1 cell lines Hematologicaldifferentiation System 1.27E-02Development of B-lymphocyteIL6 and Function derived1 cell lines Hematopoiesisdifferentiation1.27E-02 of B-lymphocyteIL6 derived1 cell lines Cellular Developmentdifferentiation1.27E-02 of blood-derivedIL6 mast1 cells Hematologicaldifferentiation System 1.27E-02Development of blood-derivedIL6 and Function mast1 cells Hematopoiesisdifferentiation1.27E-02 of blood-derivedIL6 mast1 cells Cellular Developmentdifferentiation1.27E-02 of bone marrow-derivedIL8 1 mononuclear cells Hematologicaldifferentiation System 1.27E-02Development of bone marrow-derivedIL8 and Function1 mononuclear cells Hematopoiesisdifferentiation1.27E-02 of bone marrow-derivedIL8 1 mononuclear cells Cellular Developmentdifferentiation1.27E-02 of osteoclast-likeIL8 cells1 Tissue Developmentdifferentiation1.27E-02 of osteoclast-likeIL8 cells1 Embryonic Developmentdifferentiation1.27E-02 of osteoclast-likeIL8 cells1 Connective differentiationTissue Development1.27E-02 of osteoclast-like andIL8 Function cells1 Organismaldifferentiation Development1.27E-02 of osteoclast-likeIL8 cells1 Organ Developmentdifferentiation1.27E-02 of osteoclast-likeIL8 cells1 Skeletal anddifferentiation Muscular System1.27E-02 of osteoclast-like DevelopmentIL8 cells and1 Function Small Moleculedisposal Biochemistry of D-glucose1.27E-02 IL6 1 Carbohydratedisposal Metabolism of D-glucose1.27E-02 IL6 1 Behavior drinking 1.27E-02 SOD2 1 Cell Morphologyelongation of1.27E-02 axons SLIT2 1 Cellular Assemblyelongation and of1.27E-02Organization axons SLIT2 1 Nervous Systemelongation Development of1.27E-02 axons andSLIT2 Function 1 Cellular Growthexpansion and Proliferation of1.27E-02 Th17 cellsIL6 1 Cellular Developmentexpansion of1.27E-02 Th17 cellsIL6 1 Hematologicalexpansion System of 1.27E-02Development Th17 cellsIL6 and Function1 Cellular Growthformation and Proliferation of1.27E-02 chondrocytesITGA5 1 Connective formationTissue Development of1.27E-02 chondrocytes andITGA5 Function1 Skeletal andfusion Muscular of joint System1.27E-02 DevelopmentITGA5 and1 Function Cellular Movementguidance of1.27E-02 motor axonsSLIT2 1 Nervous Systemguidance Development of1.27E-02 motor axons andSLIT2 Function 1 Gastrointestinalhepatitis Disease subtype1.27E-02 infantileIL6 hepatitis 1syndrome Inflammatoryhepatitis Disease subtype1.27E-02 infantileIL6 hepatitis 1syndrome Hepatic Systemhepatitis Disease subtype1.27E-02 infantileIL6 hepatitis 1syndrome Gastrointestinalinfantile Disease cholestatic1.27E-02 hepatitisIL6 syndrome1 Inflammatoryinfantile Disease cholestatic1.27E-02 hepatitisIL6 syndrome1 Hepatic Systeminfantile Disease cholestatic1.27E-02 hepatitisIL6 syndrome1 Cellular Compromiseinjury of kidney1.27E-02 cell linesSOD2 1 Cellular Movementmigration of1.27E-02 cd56+ naturalIL8 killer cells1 Hematologicalmigration System of 1.27E-02Development cd56+ naturalIL8 and killer Function cells1 Immune Cellmigration Trafficking of1.27E-02 cd56+ naturalIL8 killer cells1 Cell-mediatedmigration Immune of 1.27E-02 Responsecd56+ naturalIL8 killer cells1 Cellular Movementmigration of1.27E-02 cord bloodITGA5 cells 1 Cellular Movementmigration of1.27E-02 sarcoma cellSPRY2 lines 1 Renal and Urologicalmitogenesis System1.27E-02 of mesangial DevelopmentCXCL10 cells and1 Function Cell Cycle mitogenesis1.27E-02 of mesangialCXCL10 cells 1 Cellular Movementmobility of brain1.27E-02 cancerITGA5 cell lines 1 Cancer multicentric 1.27E-02castleman IL6disease 1 Skeletal andmulticentric Muscular Disorders 1.27E-02osteolysis MAFB 1 Connective multicentricTissue Disorders 1.27E-02osteolysis MAFB 1 Organ Morphologypermeability1.27E-02 of lung TIMP2 1 Respiratorypermeability System Development1.27E-02 of lung andTIMP2 Function1 Small Moleculephosphorylation Biochemistry1.27E-02 of UMPCMPK2 1 Nucleic Acidphosphorylation Metabolism1.27E-02 of UMPCMPK2 1 Small Moleculephosphorylation Biochemistry1.27E-02 of cytarabineCMPK2 1 Drug Metabolismphosphorylation1.27E-02 of cytarabineCMPK2 1 Nucleic Acidphosphorylation Metabolism1.27E-02 of cytarabineCMPK2 1 Small Moleculephosphorylation Biochemistry1.27E-02 of dCMPCMPK2 1 Nucleic Acidphosphorylation Metabolism1.27E-02 of dCMPCMPK2 1 Cell Morphologypolarization 1.27E-02of embryonicCCL5 cell lines1 Embryonic Developmentpolarization 1.27E-02of embryonicCCL5 cell lines1 Cell Morphologypolarization 1.27E-02of epithelialCCL5 cell lines 1 Hair and Skinpolarization Development 1.27E-02of epithelial and FunctionCCL5 cell lines 1 Hematologicalpolarization System 1.27E-02Developmentof hematopoieticCXCL10 and progenitorFunction1 cells Cell Morphologypolarization 1.27E-02of hematopoieticCXCL10 progenitor1 cells Hematopoiesispolarization 1.27E-02of hematopoieticCXCL10 progenitor1 cells Cell Morphologypolarization 1.27E-02of kidney cellCCL5 lines 1 Renal and Urologicalpolarization System 1.27E-02of kidney Development cellCCL5 lines and1 Function Reproductiveprimary System amenorrhea Disease1.27E-02 TGFBR3 1 Cellular Growthproduction and Proliferation of1.27E-02 blood plateletsIL6 1 Hematologicalproduction System of1.27E-02Development blood plateletsIL6 and Function1 Cellular Functionproduction and Maintenance of1.27E-02 blood plateletsIL6 1 Cellular Growthproliferation and Proliferation1.27E-02 of Tc17 cellsIL6 1 Cellular Developmentproliferation1.27E-02 of Tc17 cellsIL6 1 Hematologicalproliferation System 1.27E-02Development of Tc17 cellsIL6 and Function1 Cellular Growthproliferation and Proliferation1.27E-02 of intestinalITGA5 cell lines 1 Cellular Developmentproliferation1.27E-02 of intestinalITGA5 cell lines 1 Digestive Systemproliferation Development1.27E-02 of intestinal andITGA5 cellFunction lines 1 Cardiovascularquantity System of microvessel1.27E-02 DevelopmentIL8 and Function1 Organismalquantity Development of microvessel1.27E-02 IL8 1 Tissue Morphologyquantity of microvessel1.27E-02 IL8 1 Cellular Movementrecruitment 1.27E-02of Th17 cellsCCL5 1 Hematologicalrecruitment System 1.27E-02Developmentof Th17 cellsCCL5 and Function1 Immune Cellrecruitment Trafficking 1.27E-02of Th17 cellsCCL5 1 Cell-To-Cellrecruitment Signaling and 1.27E-02of Th17 Interaction cellsCCL5 1 Cell-mediatedrecruitment Immune 1.27E-02Responseof Th17 cellsCCL5 1 Cellular Movementrecruitment 1.27E-02of macrophagesIL8 1 Inflammatoryrecruitment Response 1.27E-02of macrophagesIL8 1 Hematologicalrecruitment System 1.27E-02Developmentof macrophagesIL8 and Function1 Immune Cellrecruitment Trafficking 1.27E-02of macrophagesIL8 1 Cell-To-Cellrecruitment Signaling and 1.27E-02of macrophages InteractionIL8 1 Cell Death andregeneration Survival1.27E-02 of liver cellsIL6 1 Cellular Developmentregeneration1.27E-02 of liver cellsIL6 1 Hepatic Systemregeneration Development1.27E-02 of liver and cells IL6Function 1 Digestive Systemregeneration Development1.27E-02 of liver andcellsIL6 Function 1 Organ Morphologyregeneration1.27E-02 of liver cellsIL6 1 Inflammatorysize Response of mast1.27E-02 cells IL6 1 Hematologicalsize System of mast 1.27E-02Development cells IL6 and Function1 Cell Morphologysize of mast1.27E-02 cells IL6 1 Hypersensitivitysize ofResponse mast1.27E-02 cells IL6 1 Cancer tumorigenesis1.27E-02 of pancreaticIL6 cancer1 cell lines Cellular Developmentdifferentiation1.28E-02 of tumor CTGF,IL6,NOV,PRDM1,SPANXCcell lines 5 (includes others) Cellular Movementmigration of1.34E-02 carcinomaIL8,NOV,PODXL cell lines 3 Cellular Growthstimulation and Proliferation of1.34E-02 cells CCL5,IL6,IL83 Cell-To-Cellstimulation Signaling andof1.34E-02 cells InteractionCCL5,IL6,IL83 Inflammatoryactivation Response of1.45E-02 blood plateletsIL6,IL8 2 Hematologicalactivation System of 1.45E-02Development blood plateletsIL6,IL8 and Function2 Cell-To-Cellactivation Signaling of and1.45E-02 blood Interaction plateletsIL6,IL8 2 Organismalactivation Functions of1.45E-02 blood plateletsIL6,IL8 2 Cellular Movementcell movement1.45E-02 of PBMCsCCL5,IL8 2 Hematologicalcell Systemmovement 1.45E-02Development of PBMCsCCL5,IL8 and Function2 Immune Cellcell Trafficking movement1.45E-02 of PBMCsCCL5,IL8 2 Cellular Developmentdifferentiation1.45E-02 of osteoclastsIL32,IL8 2 Tissue Developmentdifferentiation1.45E-02 of osteoclastsIL32,IL8 2 Embryonic Developmentdifferentiation1.45E-02 of osteoclastsIL32,IL8 2 Connective differentiationTissue Development1.45E-02 of osteoclasts andIL32,IL8 Function2 Organismaldifferentiation Development1.45E-02 of osteoclastsIL32,IL8 2 Organ Developmentdifferentiation1.45E-02 of osteoclastsIL32,IL8 2 Skeletal anddifferentiation Muscular System1.45E-02 of osteoclasts DevelopmentIL32,IL8 and2 Function Cell-To-Cellbinding Signaling of tumorand1.46E-02 Interaction cell linesFERMT2,IL6,ITGA5,PTPRM4 Hematologicalquantity System of leukocytes 1.48E-02DevelopmentIL6,IL7R,IL8 and Function3 Tissue Morphologyquantity of leukocytes1.48E-02 IL6,IL7R,IL83 Cancer ovarian tumor1.50E-02 AXL,IDO1,IL6,IL8,MSX1,RUNX3,SLIT2,TIMP18 Reproductiveovarian System tumor Disease1.50E-02 AXL,IDO1,IL6,IL8,MSX1,RUNX3,SLIT2,TIMP18 InflammatoryKawasaki's Disease 1.55E-02disease TIMP1,TIMP22 CardiovascularKawasaki's Disease 1.55E-02disease TIMP1,TIMP22 Cell Death andapoptosis Survival of1.55E-02 neutrophilsIL6,IL8 2 Gastrointestinalchronic Disease hepatitis1.55E-02 B IL6,TIMP1 2 Inflammatorychronic Disease hepatitis1.55E-02 B IL6,TIMP1 2 Infectious Diseasechronic hepatitis1.55E-02 B IL6,TIMP1 2 Hepatic Systemchronic Disease hepatitis1.55E-02 B IL6,TIMP1 2 Cellular Developmentdevelopment1.55E-02 of hematopoieticIL6,IL7R progenitor2 cells Hematologicaldevelopment System 1.55E-02Development of hematopoieticIL6,IL7R and Function progenitor2 cells Hematopoiesisdevelopment1.55E-02 of hematopoieticIL6,IL7R progenitor2 cells Cell Death andcell deathSurvival of1.57E-02 breast cancerCTGF,FRMD6,PMAIP1,SFRP1,SOD2,TGFBR3 cell lines6 Cellular Growthproliferation and Proliferation1.58E-02 of bone cancerCTGF,EMILIN2,NOV cell lines3 Cellular Developmentproliferation1.58E-02 of bone cancerCTGF,EMILIN2,NOV cell lines3 Cell Death andapoptosis Survival of1.65E-02 smooth muscleIL8,PMAIP1 cells 2 Inflammatoryimmune Response response1.65E-02 of neutrophilsCXCL10,IL82 Hematologicalimmune System response 1.65E-02Development of neutrophilsCXCL10,IL8 and Function2 Cell-To-Cellimmune Signaling response and1.65E-02 Interaction of neutrophilsCXCL10,IL82 Cellular Movementinvasion of pancreatic1.65E-02 cancerTIMP1,TIMP2 cell lines2 Cellular Growthproliferation and Proliferation1.65E-02 of myelomaIL6,SOD2 cell lines 2 Cellular Developmentproliferation1.65E-02 of myelomaIL6,SOD2 cell lines 2 Cellular Growthproliferation and Proliferation1.68E-02 of smooth CCL5,IL6,IL8muscle cells3 Cellular Developmentproliferation1.68E-02 of smooth CCL5,IL6,IL8muscle cells3 Skeletal andproliferation Muscular System1.68E-02 of smooth Development CCL5,IL6,IL8muscle cells and3 Function Cancer bone marrow1.69E-02 cancer AXL,CD70,IL6,IL7R,IL8,ITGA5,PXDN7 Hematologicalbone Disease marrow1.69E-02 cancer AXL,CD70,IL6,IL7R,IL8,ITGA5,PXDN7 Cellular Movementcell movement1.74E-02 of colonAXL,CXCL10,FERMT2 cancer cell3 lines Cellular Movementmigration of1.74E-02 vascular endothelialSLIT2,TIMP1,TIMP2 cells3 Cardiovascularmigration System of1.74E-02 Developmentvascular endothelialSLIT2,TIMP1,TIMP2 and Function cells3 Gastrointestinalprimary Disease biliary1.74E-02 cirrhosisCTGF,IL7R,ITGA53 Inflammatoryprimary Disease biliary1.74E-02 cirrhosisCTGF,IL7R,ITGA53 Hepatic Systemprimary Disease biliary1.74E-02 cirrhosisCTGF,IL7R,ITGA53 Organismalprimary Injury and biliary Abnormalities1.74E-02 cirrhosisCTGF,IL7R,ITGA53 Cellular Movementchemotaxis1.74E-02 of phagocytesCCL5,CXCL10,IL8,SLIT24 Inflammatorychemotaxis Response1.74E-02 of phagocytesCCL5,CXCL10,IL8,SLIT24 Hematologicalchemotaxis System 1.74E-02 Developmentof phagocytesCCL5,CXCL10,IL8,SLIT2 and Function4 Immune Cellchemotaxis Trafficking1.74E-02 of phagocytesCCL5,CXCL10,IL8,SLIT24 Infectious Diseaserelease of virus1.75E-02 BST2,RSAD22 DNA Replication,synthesis Recombination, of1.78E-02 DNA andCCL5,CXCL10,IL6,IL8,TIMP2 Repair 5 Inflammatoryinflammatory Response1.83E-02 responseCCL5,CXCL10,IL6,IL8,PTGER4,SLIT26 Inflammatoryacute Disease respiratory1.85E-02 distressIL6,IL8 syndrome2 Respiratoryacute Disease respiratory1.85E-02 distressIL6,IL8 syndrome2 Organismalacute Injury respiratory and Abnormalities1.85E-02 distressIL6,IL8 syndrome2 Renal and Urologicalhydronephrosis Disease1.85E-02 CD70,IL8 2 Infectious Diseaseproduction of1.85E-02 HIV-1 BST2,RSAD22 Hereditary DisorderGraves' ophthalmopathy1.89E-02 IL6 1 Endocrine SystemGraves' Disorders ophthalmopathy1.89E-02 IL6 1 ImmunologicalGraves' Disease ophthalmopathy1.89E-02 IL6 1 Ophthalmic Graves'Disease ophthalmopathy1.89E-02 IL6 1 Metabolic DiseaseGraves' ophthalmopathy1.89E-02 IL6 1 Tissue Developmentaccumulation1.89E-02 of hepatomaIL6 cell lines1 Cell-To-Cellactivation Signaling of and1.89E-02 fibroblasts InteractionIL6 1 Connective activationTissue Development of1.89E-02 fibroblasts andIL6 Function1 Hematologicalaggregation System 1.89E-02Development of hematopoieticCXCL10 and progenitorFunction1 cells Tissue Developmentaggregation1.89E-02 of hematopoieticCXCL10 progenitor1 cells Hematopoiesisaggregation1.89E-02 of hematopoieticCXCL10 progenitor1 cells Cell Cycle arrest in G11.89E-02 phase of skinTIMP2 cell lines1 Cellular Movementarrest in migration1.89E-02 of eosinophilsIL8 1 Hematologicalarrest System in migration 1.89E-02Development of eosinophilsIL8 and Function1 Immune Cellarrest Trafficking in migration1.89E-02 of eosinophilsIL8 1 Hypersensitivityarrest Response in migration1.89E-02 of eosinophilsIL8 1 Cellular Developmentbranching of1.89E-02 axons SLIT2 1 Cell Morphologybranching of1.89E-02 axons SLIT2 1 Tissue Developmentbranching of1.89E-02 axons SLIT2 1 Embryonic Developmentbranching of1.89E-02 axons SLIT2 1 Cellular Assemblybranching and of 1.89E-02Organization axons SLIT2 1 Cellular Functionbranching and Maintenanceof1.89E-02 axons SLIT2 1 Nervous Systembranching Development of1.89E-02 axons andSLIT2 Function 1 Cell Morphologycell spreading1.89E-02 of keratinocytesITGA5 1 Hair and Skincell Development spreading1.89E-02 of andkeratinocytes FunctionITGA5 1 Cell-To-Cellcell-cell Signaling adhesion and1.89E-02 Interaction of embryonicTIMP1 cell1 lines Tissue Developmentcell-cell adhesion1.89E-02 of embryonicTIMP1 cell1 lines Embryonic Developmentcell-cell adhesion1.89E-02 of embryonicTIMP1 cell1 lines Cell-To-Cellcell-cell Signaling adhesion and1.89E-02 Interaction of epithelialTIMP1 cell lines1 Tissue Developmentcell-cell adhesion1.89E-02 of epithelialTIMP1 cell lines1 Hair and Skincell-cell Development adhesion1.89E-02 and of epithelialFunctionTIMP1 cell lines1 Inflammatorycervical Disease posterior1.89E-02 longitudinalCOL6A1 ligament1 ossification Neurologicalcervical Disease posterior1.89E-02 longitudinalCOL6A1 ligament1 ossification Skeletal andcervical Muscular posterior Disorders1.89E-02 longitudinalCOL6A1 ligament1 ossification Connective cervicalTissue Disordersposterior1.89E-02 longitudinalCOL6A1 ligament1 ossification Cellular Movementchemoattraction1.89E-02 of monocytesCCL5 1 Inflammatorychemoattraction Response1.89E-02 of monocytesCCL5 1 Hematologicalchemoattraction System 1.89E-02Development of monocytesCCL5 and Function1 Immune Cellchemoattraction Trafficking1.89E-02 of monocytesCCL5 1 Cell-To-Cellchemoattraction Signaling and1.89E-02 Interaction of monocytesCCL5 1 Cellular Movementchemorepulsion1.89E-02 of commissuralSLIT2 neurons1 Nervous Systemchemorepulsion Development1.89E-02 of commissuralandSLIT2 Function neurons1 Cellular Movementchemotaxis1.89E-02 of hepatic stellateCXCL10 cells1 Connective chemotaxisTissue Development1.89E-02 of hepatic and stellateCXCL10 Function cells1 Hepatic Systemchemotaxis Development1.89E-02 of hepatic and stellate CXCL10Function cells1 Post-Translationalconjugation Modification1.89E-02 of protein HERC5 1 Protein Foldingconjugation1.89E-02 of protein HERC5 1 Cancer cytotoxic reaction1.89E-02 of hepatomaIL6 cell1 lines Inflammatorycytotoxic Response reaction1.89E-02 of hepatomaIL6 cell1 lines Cell-To-Cellcytotoxic Signaling reaction and1.89E-02 Interaction of hepatomaIL6 cell1 lines Cell-To-Celldetachment Signaling and1.89E-02 of embryonicInteractionSOD2 cell lines1 Tissue Developmentdetachment1.89E-02 of embryonicSOD2 cell lines1 Embryonic Developmentdetachment1.89E-02 of embryonicSOD2 cell lines1 Cell-To-Celldetachment Signaling and1.89E-02 of kidneyInteraction cellSOD2 lines 1 Tissue Developmentdetachment1.89E-02 of kidney cellSOD2 lines 1 Renal and Urologicaldetachment System1.89E-02 of kidney Development cellSOD2 lines and1 Function Cellular Developmentdifferentiation1.89E-02 of peripheralIL6 T lymphocyte1 Hematologicaldifferentiation System 1.89E-02Development of peripheralIL6 and T lymphocyteFunction1 Cellular Functiondifferentiation and Maintenance1.89E-02 of peripheralIL6 T lymphocyte1 Hematopoiesisdifferentiation1.89E-02 of peripheralIL6 T lymphocyte1 Cell-mediateddifferentiation Immune 1.89E-02Response of peripheralIL6 T lymphocyte1 Lymphoid Tissuedifferentiation Structure1.89E-02 of and peripheral DevelopmentIL6 T lymphocyte1 Inflammatoryelderly-onset Disease 1.89E-02 rheumatoidIL6 arthritis 1 Skeletal andelderly-onset Muscular Disorders1.89E-02 rheumatoidIL6 arthritis 1 Immunologicalelderly-onset Disease1.89E-02 rheumatoidIL6 arthritis 1 Connective elderly-onsetTissue Disorders1.89E-02 rheumatoidIL6 arthritis 1 Free Radicalformation Scavenging of1.89E-02 hydrogen peroxideIL6 1 Small Moleculeformation Biochemistry of1.89E-02 hydrogen peroxideIL6 1 Hematologicalidiopathic Disease myelofibrosis1.89E-02 SH2B3 1 Cancer infection of 1.89E-02fibrosarcomaAXL cell lines 1 Infectious Diseaseinfection of 1.89E-02fibrosarcomaAXL cell lines 1 Neurologicalinfluenza Disease with1.89E-02 encephalopathyTIMP1 1 Infectious Diseaseinfluenza with1.89E-02 encephalopathyTIMP1 1 Cellular Growthinhibition and Proliferationof 1.89E-02monocytesITGA5 1 Hematologicalinhibition System of 1.89E-02DevelopmentmonocytesITGA5 and Function1 Cellular Movementinvasion of tumor-infiltrating1.89E-02 IL8 lymphocytes1 Cellular Movementmigration of1.89E-02 cytotoxic TCXCL10 cells 1 Hematologicalmigration System of 1.89E-02Development cytotoxic TCXCL10 cells and Function1 Immune Cellmigration Trafficking of1.89E-02 cytotoxic TCXCL10 cells 1 Cell-mediatedmigration Immune of 1.89E-02 Responsecytotoxic TCXCL10 cells 1 Cellular Movementmigration of1.89E-02 mast cells CCL5 1 Inflammatorymigration Response of1.89E-02 mast cells CCL5 1 Hematologicalmigration System of 1.89E-02Development mast cells CCL5 and Function1 Immune Cellmigration Trafficking of1.89E-02 mast cells CCL5 1 Hypersensitivitymigration Response of1.89E-02 mast cells CCL5 1 Cellular Movementmigration of1.89E-02 rhabdomyosarcomaNOV cell1 lines Dermatologicalmonilethrix Diseases1.89E-02 and ConditionsKRT81 1 Hereditary Disordermonilethrix 1.89E-02 KRT81 1 Post-Translationalnitration Modification of protein1.89E-02 SOD2 1 Tissue Developmentorganization1.89E-02 of extracellularPXDN matrix1 Reproductiveovulation System of Development1.89E-02 ovary IL6 and Function1 Inflammatorypolymyalgia Disease 1.89E-02 rheumaticaIL6 1 Skeletal andpolymyalgia Muscular Disorders1.89E-02 rheumaticaIL6 1 Connective polymyalgiaTissue Disorders1.89E-02 rheumaticaIL6 1 Cellular Growthproduction and Proliferation of1.89E-02 neutrophilsIL6 1 Hematologicalproduction System of1.89E-02Development neutrophilsIL6 and Function1 Cellular Functionproduction and Maintenance of1.89E-02 neutrophilsIL6 1 Cellular Growthproliferation and Proliferation1.89E-02 of Kaposi'sIL6 sarcoma cells1 Cellular Developmentproliferation1.89E-02 of Kaposi'sIL6 sarcoma cells1 Tumor Morphologyproliferation1.89E-02 of Kaposi'sIL6 sarcoma cells1 Cellular Growthproliferation and Proliferation1.89E-02 of endometrioticIL8 stromal1 cells Cellular Developmentproliferation1.89E-02 of endometrioticIL8 stromal1 cells Reproductiveproliferation System Development1.89E-02 of endometrioticIL8 and Functionstromal1 cells Connective proliferationTissue Development1.89E-02 of endometriotic andIL8 Function stromal1 cells Cellular Growthproliferation and Proliferation1.89E-02 of pulmonaryITGA5 fibroblasts1 Cellular Developmentproliferation1.89E-02 of pulmonaryITGA5 fibroblasts1 Connective proliferationTissue Development1.89E-02 of pulmonary andITGA5 Functionfibroblasts1 Respiratoryproliferation System Development1.89E-02 of pulmonary andITGA5 fibroblasts Function1 Inflammatorypseudogout Disease 1.89E-02 IL6 1 Skeletal andpseudogout Muscular Disorders1.89E-02 IL6 1 Connective pseudogoutTissue Disorders1.89E-02 IL6 1 Inflammatoryquantity Response of mast1.89E-02 cells IL6 1 Hematologicalquantity System of mast 1.89E-02Development cells IL6 and Function1 Hypersensitivityquantity Response of mast1.89E-02 cells IL6 1 Tissue Morphologyquantity of mast1.89E-02 cells IL6 1 Gastrointestinalreflux Disease esophagitis1.89E-02 IL8 1 Inflammatoryreflux Disease esophagitis1.89E-02 IL8 1 Free Radicalremoval Scavenging of superoxide1.89E-02 SOD2 1 Infectious Diseasereplication of1.89E-02 SARS coronavirusIFITM1 1 Molecular Transportsecretion of1.89E-02 histamine IL8 1 Small Moleculesecretion Biochemistry of1.89E-02 histamine IL8 1 Molecular Transportsecretion of1.89E-02 leukotrieneIL8 C4 1 Small Moleculesecretion Biochemistry of1.89E-02 leukotrieneIL8 C4 1 Lipid Metabolismsecretion of1.89E-02 leukotrieneIL8 C4 1 Cancer survival of chronic1.89E-02 lymphocyticIL8 leukemia1 B cells Cell Death andsurvival Survival of chronic1.89E-02 lymphocyticIL8 leukemia1 B cells Tumor Morphologysurvival of chronic1.89E-02 lymphocyticIL8 leukemia1 B cells Cancer survival of glioma1.89E-02 cells SFRP1 1 Cell Death andsurvival Survival of glioma1.89E-02 cells SFRP1 1 Tumor Morphologysurvival of glioma1.89E-02 cells SFRP1 1 Cell Morphologytransepithelial1.89E-02 electricalLPAR1 resistance 1of bronchial epithelial cells Hair and Skintransepithelial Development1.89E-02 electrical and FunctionLPAR1 resistance 1of bronchial epithelial cells Cell Death andapoptosis Survival of1.96E-02 lymphoblastoidIL6,SOD2 cell lines2 Cancer rectum cancer1.96E-02 IL6,SOD2 2 Gastrointestinalrectum Disease cancer1.96E-02 IL6,SOD2 2 Cardiovascularatherosclerosis Disease1.98E-02 IL6,KLF6,PTPRM,RSAD2,TIMP1,TIMP26 Cell Death andcell deathSurvival of1.98E-02 cervical cancerEMILIN2,IL32,IL6,MSX1,PMAIP1,SOD2 cell lines6 Molecular Transportaccumulation2.07E-02 of inositolCCL5,CXCL10 phosphate2 Small Moleculeaccumulation Biochemistry2.07E-02 of inositolCCL5,CXCL10 phosphate2 Carbohydrateaccumulation Metabolism2.07E-02 of inositolCCL5,CXCL10 phosphate2 Cellular Movementcell movement2.07E-02 of hematopoieticCCL5,CXCL10 progenitor2 cells Hematologicalcell Systemmovement 2.07E-02Development of hematopoieticCCL5,CXCL10 and Function progenitor2 cells Cellular Growthcolony and formation Proliferation2.07E-02 of lungKLF6,SOD2 cancer cell2 lines Cellular Functionengulfment and Maintenance 2.07E-02of leukocytesCCL5,CXCL102 Cellular Developmenttubulation of2.07E-02 vascular endothelialIL8,SLIT2 cells2 Cell Morphologytubulation of2.07E-02 vascular endothelialIL8,SLIT2 cells2 Tissue Developmenttubulation of2.07E-02 vascular endothelialIL8,SLIT2 cells2 Cardiovasculartubulation System of2.07E-02 Developmentvascular endothelialIL8,SLIT2 and Function cells2 Organismaltubulation Development of2.07E-02 vascular endothelialIL8,SLIT2 cells2 Cellular Growthproliferation and Proliferation2.07E-02 of lymphomaIDO1,IL6,PRDM1 cell lines3 Cellular Developmentproliferation2.07E-02 of lymphomaIDO1,IL6,PRDM1 cell lines3 Cancer non-Hodgkin's2.08E-02 diseaseCD70,CXCL10,IL6,IL8,PRDM15 Hematologicalnon-Hodgkin's Disease2.08E-02 diseaseCD70,CXCL10,IL6,IL8,PRDM15 Cell Cycle cell cycle progression2.14E-02 AXL,CXCL10,FRMD6,GAS1,IL6,IL8,IRF7,KLF6,MX2,SPRY210 Immunologicaldelayed Disease hypersensitive2.19E-02 IFITM1,SOD2reaction 2 Cardiovascularstenosis Disease of aortic2.19E-02 valveTIMP1,TIMP22 Organismalstenosis Injury and of Abnormalitiesaortic2.19E-02 valveTIMP1,TIMP22 Immunologicalhypersensitive Disease2.19E-02 reactionCCL5,IFITM1,IL8,PHF11,SOD2,TIMP16 DermatologicalAcne Diseases2.19E-02 and ConditionsIL8,SOD2,TIMP13 InflammatoryAcne Disease 2.19E-02 IL8,SOD2,TIMP13 Free Radicalmetabolism Scavenging2.21E-02 of reactive CCL5,IL6,IL8,PXDN,SOD2oxygen species5 Cell Death andcell deathSurvival of2.25E-02 lymphoblastoidCDA,IL6,SOD2 cell lines3 Inflammatoryactivation Response of2.38E-02 phagocytesCCL5,IL6,IL83 Hematologicalactivation System of 2.38E-02Development phagocytesCCL5,IL6,IL8 and Function3 Immune Cellactivation Trafficking of2.38E-02 phagocytesCCL5,IL6,IL83 Cell-To-Cellactivation Signaling of and2.38E-02 phagocytes InteractionCCL5,IL6,IL83 Cell Death andapoptosis Survival of2.42E-02 hematopoieticCCL5,IL6 progenitor2 cells Cancer cell viability 2.42E-02of cancer cellsIL8,SFRP1 2 Cell Death andcell viabilitySurvival 2.42E-02of cancer cellsIL8,SFRP1 2 Tumor Morphologycell viability 2.42E-02of cancer cellsIL8,SFRP1 2 Cellular Growthproliferation and Proliferation2.42E-02 of lymphoblastoidRUNX3,SOD2 cell 2lines Cellular Developmentproliferation2.42E-02 of lymphoblastoidRUNX3,SOD2 cell 2lines Infectious Diseasesepsis 2.44E-02 AXL,IL6,IL83