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www.providenceresearch.ca February 2009

RESEARCH EVENTS MESSAGE FROM YVONNE LEFEBVRE ALL ARE WELCOME TO ATTEND VP RESEARCH & ACADEMIC AFFAIRS February 6th While our success and growth in research increased in 2008, Clinical Research Seminar Series events both internationally and nationally are likely to impact Working with community partners in research investment in Canada. The Federal budget tabled last research - Dr. Mark Tyndall week sent a shudder through the Canadian scientific Hurlburt Auditorium, SPH, 12:00-1:00pm community. (If you would like to voice your concerns to your February 9th Member of Parliament, attached is a Research Canada advocacy iCAPTURE Research in Progress Series template letter). Provincially, we are anticipating a spring Accelerated Aging and Sex Differences in election and investments to be announced for the Michael COPD - Tammy Mui Smith Foundation for Health Research. And locally the CEO of Gourlay Conference Room, SPH, the Vancouver Coastal Health Authority, Ida Goodreau, 9:00-10:00am resigned. The only thing that is certain is that change is coming.

th February 11 With all the change in the world in the past few months, I would like to first CHÉOS Work in Progress recognize the success of many Providence Researchers and their teams. Of note are Lorne Korman the recent CIHR Operating grant awards listed on page 2 and the attached list of Hurlburt Auditorium, SPH, 12:00-1:00pm MSFHR awardees and Faculty of Medicine recognition awardees. I want to invite February 13th everyone to join us on March 9th for our annual Research Day event to celebrate iCAPTURE: Seminar Series research accomplishments. Every year we celebrate our success, recognize an Airway Smooth Muscle: More Than individual scientist who embodies the Research and Mission of Providence and Shortening - Reynold A. Panettieri, M.D., invite a keynote speaker to share their wisdom. This year's lunch event features Dr. Robert L. Mayock and David A. Cooper Frank Plummer, Professor of Medicine and Medical Microbiology, University of New Lecture Theatre, Providence Building, Manitoba; and Scientific Director General, National Microbiology Laboratory, Public Level 1 11:30-12:30pm Health Agency of Canada. Please register early for this special event, space is limited (to register e-mail [email protected]). th February 20 iCAPTURE: Seminar Series This month the Research Institute is involved in "BioPartnering North America". We Long QT syndrome Type I in a BC are aiming to increase the profile of the great research we do and seeking strategic aboriginal population: From community studies to mechanistic understanding - partnership with industry. The Office of Research Services welcomes Christy David Fedida, M.B., B.Sc., Ph.D., B.M. B.Ch Costello to the role of Ethics Coordinator and Jennifer Kennedy to the role of New Lecture Theatre, Providence Building, Research Communications Coordinator. Level 1 11:30-12:30pm -Yvonne Lefebvre

February 25th CHÉOS Work in Progress PHCRI RESEARCHER PROFILE Rob Stenstrom Geoffrey W. Cundiff, MD Hurlburt Auditorium, SPH, 12:00-1:00pm Professor, Department of Obstetrics and Gynaecology February 27th and Associate, Department of Urological Sciences, UBC; Head Department of Obstetrics & Gynaecology iCAPTURE: Seminar Series and Physician Program Director Maternity Service, Protection from atopy and asthma in rural PHC; CHÉOS Researcher communities - genetic and environmental determinants - Dr. Erika Von Mutius Research Interests Gourlay Conference Room, SPH, 11:30- 12:30pm · Surgical Outcomes Research for Pelvic Floor Dysfunction · Epidemiology of Pelvic Floor Disorders · Prevention of Maternal Obstetrical Trauma

MARCH GRANT UPCOMING EVENTS

NOTICES & DEADLINES FEBRUARY 6-7: COPD FEBRUARY 13: HOEDOWN FOR MARCH 10: HEART+ LUNG FEST CONFERENCE AND PUBLIC The Heart + Lung FEST is sponsored HEARTS FORUM by the PROOF Centre of Excellence. The 3rd Annual Hoedown for The event takes place at the CIHR: Centres for Research COPD: Reactive Past, Preventive Hearts is a benefit event in support Sheraton Wall Centre. To register Development in Gender, Mental Future brings together the world's of heart research at the iCAPTURE email: [email protected] Health and Addictions leading clinicians and researchers to Centre and Heart and Stroke

celebrate 30 years of excellence in Foundation. 8pm Boone County lung research at the James Hogg MARCH18: PHCRI RESEARCHERS CIHR Team Grant: Clinical Imaging Cabaret in Coquitlam. For more iCAPTURE Centre. information call 604-806-8346 or ABROAD www.copd2009.com email [email protected] PHCRI Researchers Abroad lecture

CIHR Chair: GlaxoSmithKline series celebrates international FEBRUARY 10: PHCRI CLINICAL Partnered MARCH 9: RESEARCH DAY calibre research at PHC. Please join COORDINATORS NETWORK th PHCRI Research Day features us on March 18 for a presentation All research staff are welcome to keynote speaker, Dr. Frank Plummer by CHEOS researcher Dr. Patty CIHR Operating Grant: Small and attend the next PHCRI Clinical Professor of Medicine and Medical Spittal. Hurlburt Auditorium, SPH, Medium Enterprize Coordinators Network meeting. Microbiology, University of 12-1pm. Please register by email at: This session will provide an Manitoba; and Scientific Director [email protected] orientation to quality standards for General, National Microbiology CIHR Operating Grant clinical research. The meeting will Laboratory, Public Health Agency of FEB. 10 & 24: TOASTMASTERS be held from 9-11am in iCAPTURE’s Canada. Join us at the Century Gourlay Conf. Rm, SPH, 12–1 pm. Gourlay Conference Room, SPH. CIHR: Operating Grant: Rx&D Plaza Hotel for this special event. Contact [email protected] for Please register before February 9th: Collaborative Research more information. [email protected] Please register, as space is limited: [email protected] 2009 MSFHR Seed Funding Competition ANNOUNCEMENTS Title: A Collaborative Quality Improvement Banting Research Foundation CIHR SUCCESS Model and Electronic Community of Practice to Grants Congratulations to the following researchers and Support Sepsis Management in Emergency teams for their operating grant funding success: Departments: Investigating Care Harmonization for Provincial Knowledge Translation. CI: Robert Martha Piper Research Fund Title: An Integrated Approach to Blood Stenstrom Biomarker Discoveries in COPD. PIs:Paul Man & DoD Neurofibromatosis Research Don Sin CIs: Harvey Coxson, David Granville, Jim Title: The Cedar Project: Exploring HIV and and Clinical Trial Awards Hogg, Stephen Lam Hepatitis C Vulnerabilities among Young Aboriginal Drug Users in Three Canadian Cities. Title: Realities, Expectations and Attitudes to DoD Tuberous Sclerosis Complex PIs: Patty Spittal and Martin Schechter CIs: Kevin Life Support Technologies in Intensive Care for Research and Idea Development Craib, Reinhard Krausz, Akm Moniruzzaman, Octogenarians. CIs: Jean-Francois Kozak and Awards Eugenia Oviedo-Joekes and Chris Richardson Peter Dodek

Heart and Stroke Foundation Title: Longitudinal comparison of quality of life Title: Improved screening methods for Nursing Research Fellowship among kidney transplant recipients and CCR5_Antagonists use by ultra deep sequencing nocturnal home hemodialysis patients. CI: John and quantitative population. PIs: Richard The Heart and Stroke Foundation Gill Harrigan and Arthur Poon CIs: Peter Cheung, Request for Proposals Viviane Lima

Title: Macrophage polarization and the development of artherosclerosis. PI: John Hill Title: Understanding virological and host (pending) determinants of HIV disease progression in a RESEARCH ETHICS BOARD cohort of slow progressors. CIs: Marianne Harris, Title: Genome-wide association of aortic valve Julio Montaner MARCH DATES stenosis. PIs: Angela Brooks-Wilson and Bruce FOR FULL BOARD REVIEW McManus CI: Peter Pare Please contact us if you received an award not listed above: [email protected]

REB Meeting PHC RESEARCH INSTITUTE CONTACTS Friday, March 27, 2009 VP Research & Academic Affairs Finance Manager Submission Deadline* Yvonne Lefebvre, PhD, x68903 Jo-Lynn Mervyn, x69146

Friday, March 6, 4:00 pm Research Institute Accountant VP Executive Assistant PHC Research Institute Freda Liang, x63438 Gail Dibernardo, x69608 Office of Research Services * Submissions must be approved by the 1190 Hornby Street, 11th Floor Department Head and entered in RISe by Research Accounts Bookkeeper Research Services Director Vancouver, BC V6Z 2K5 this time. It is recommended that Cindy Paddon, x62843 Meg Hughes, x69464 applications be sent to the Department Ethics, Review Coordinator Office Hours: 8:00-4:00, M–F Head at least 3 days in advance of the Ethical Review Manager Christy Costello, x68567 T: 604-806-8567 Vivienne Bearder, x63496 submission deadline. F: 604-806-8568 Grants and Contracts Coordinator W: http://www.providenceresearch.ca Clinical Research Contracts Manager Gwen Sin, x69102 Esther Wu, x63199 E: [email protected] Communications Coordinator Jennifer Kennedy x68175 Human Resources Manager Kelly Ceron, x68570

Congratulations to 2008 MSFHR Trainee and UBC Faculty of Medicine Special Recognition Award Recipients!

MSFHR 2007-2008 Trainee Award Competition:

Biomedical Junior Graduate Studentship: Lisa Ang, Supervisor Dr. David Granville – “The role of arachidonic acid metabolism in the pathogenesis of atherosclerosis”

Biomedical Junior Graduate Studentship: David Lin, Supervisors Dr. Bruce McManus and Dr. Honglin Luo – “Vascular endothelial growth factor signaling in cardiac allograft vasculopathy”

Clinical Senior Graduate Studentship: Claire Heslop, Supervisor Dr. John Hill – “Prediction of cardiovascular mortality in patients with coronary artery disease using plasma and genetic markers of oxidative stress”

Clinical Post-Doctoral: Viviane Lima, Supervisors Dr. Julio Montaner and Dr. Robert Hogg – “Examining the interplay between adherence and antiretroviral treatment on disease outcomes over time in HIV/AIDS infected patients”

Health Services Junior Graduate Studentship: Aranka Anema, Supervisor Dr. Julio Montaner – “Assessing the impacts of social, sexual and drug-use networks on HIV-positive Aboriginals receiving highly active anti- retroviral therapy (HAART) in British Columbia”

Health Services Senior Graduate Studentship: Suze Berkhout, Supervisors Dr. Mark Tyndall and Dr. Scott Anderson – “Exploring the social structural dynamics of health barriers and determinants of women in Vancouver's survival sex trade: An ethnographic study”

Health Services Senior Graduate Studentship: Jennifer Davis, Supervisors Dr. Aslam Anis and Dr. Carlo Marra – “Economic studies of seniors at high risk of falls”

Population Health Junior Graduate Studentship: Daniel Werb, Supervisor Dr. Thomas Kerr – “Investigating syringe-sharing among at-risk youth, and analyzing coverage of and access to youth-targeted needle exchange programs”

Population Health Senior Graduate Studentship: Kora DeBeck, Supervisor Dr. Julio Montaner – “Urban renewal, drug related disorder and displacement: Implications for health and HIV risk behaviour among injection drug using populations”

Population Health Senior Graduate Studentship: Kathleen Deering, Supervisor Dr. Mark Tyndall – “Optimizing the impact of antiretroviral treatment as an HIV prevention intervention in marginalized populations”

Population Health Senior Graduate Studentship: Brandon Marshall, Supervisor Dr. Thomas Kerr – “An investigation of the impact of crystal methamphetamine use on sexual and injection-related risk behaviour among street youth and injection drug users in Vancouver”

Biomedical Scholar Award: Dr. Pascal Bernatchez – “Increased nitric oxide bioavailability through regulated eNOS-Caveolin-1 antagonism”

Biomedical Scholar Award: Dr. Andrew Sandford – “Genetic susceptibility to inflammatory airway diseases”

Biomedical Post Doctoral Award: Dr. Minnie Dai – Supervisor Dr. Michael Allard “The role of AMP-activated protein kinase on glycolysis and myocardial remodeling in the hypertrophied heart”

Clinical Scholar Award: Dr. Delbert Dorscheid, - “IL-13 and the glycomics of airway epithelial repair”

Health Services Senior Scholar Award: Dr. Karin Humphries - “Sex differences in patients presenting with acute myocardial infarction or chest pain without angiographic evidence of coronary disease”

MSFHR Career Scholar Award: Denise Daley PhD iCAPTURE Research Centre - “The genetics of asthma, atopy and allergic diseases”

UBC Faculty of Medicine 2007-2008

Distinguished Achievement Award for Excellence in Clinical or Applied Research: Dr. Karin Humphries CHEOS

Martin M. Hoffman Award for Excellence in Research: Dr. Karin Humphries CHEOS

Richard A. Robertson Memorial Service Award in Medicine: Brandon Marshall BCCfE

2007 Distinguished Medical Research Lecturer Award in Basic Science Research: Dr. Bruce McManus iCAPTURE Research Centre

Dorothy Helmer Scholarship in Medicine: Jerry Wong iCAPTURE Research Centre

UBC Department of Pathology and Laboratory Medicine David F. Hardwick Lifetime Achievement Award: Dr. Bruce McManus iCAPTURE Research Centre

UBC Department of Medicine Faculty Research Award: Dr. Karin Humphries CHEOS

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http://www.providenceresearch.ca/ March 2009

PHCRI RESEARCH EVENTS MESSAGE FROM YVONNE LEFEBVRE ALL ARE WELCOME TO ATTEND VP RESEARCH & ACADEMIC AFFAIRS March 2nd The research landscape in Canada is changing due to a shift in iCAPTURE Research in Progress Series economic conditions. Last month the Canadian government Role of Wnt/ß-catenin Signaling Pathway in tabled its federal budget outlining its economic stimulus plan. Aortic Valve Calcification - Seti Boroomand Gourlay Conference Room, SPH, 9:00-10:00am This week, the Canada Foundation for Innovation (CFI) and the Canadian Institutes of Health Research (CIHR) circulated their March 6th summaries of the impact of the budget announcements on the iCAPTURE: Seminar Series national funding programs (letters attached for your Biomechanical Control of Vascular information). While CFI received a $750 million increase the Development and Function - Guillermo Garcia- CIHR did not see substantial new investments. The Research Cardena Gourlay Conference Room, SPH, 2:00-3:00pm Institute will support strategic applications to CFI and CIHR to ensure our research programs continue to succeed. March 9th PHCRI Research Day The importance and impact of CIHR funding to the health research community in Keynote Speaker Dr. Frank Plummer Canada is substantial. In 2008, Providence researchers were awarded $29.1 million in To register: 604-806-8175 or external research awards. One third of the awards ($9 million) were the result of [email protected] successful CIHR applications. With the March 2009 CIHR funding deadline looming, Burrard Ballroom, Century Plaza Hotel, CIHR released results of the September competition. Nationally, CIHR received 1,824 11:00am-1:00pm applications of which 394 were funded (21.6% success). Providence researchers were

involved in 42 CIHR applications, of which 11 grants were funded. As Primary March 9th Investigators, our success rate was 17% and as co-applicants our success rate was iCAPTURE Research in Progress Series Comparison of performance between General 39%. If you are involved in an application for the March 2009 competition, please Electric, Philips, and Siemens reconstruction contact the Office of Research Services so we can facilitate the institutional software packages for SPECT using a approvals required. standardized phantom - Tyler Hughes Gourlay Conference Room, SPH, 9:00-10:00am March is an important month for the UBC research community. UBC Research Week involves events across the city showcasing and highlighting research. Please March 10th Heart + Lung FEST join us on March 9th for Research Day, our annual celebration of research Sponsored by PROOF Centre of Excellence. To achievements. "Research in the Heart of a City" is the theme and our keynote register: [email protected] speaker is Dr Frank Plummer, a leading Canadian scientist in HIV/AIDS. We will Grand Ballroom, Sheraton Wall Centre, 7:30am- recognize a leading scientist with the "Research and Mission" award. I look forward 4:45pm to seeing everyone on March 9th, please RSVP to [email protected].

th -Yvonne Lefebvre March 11 CHÉOS Work in Progress The Relationship Between Organizational GUEST RESEARCHER PROFILE Culture and Family Satisfaction in Critical Care Dr. Peter Dodek Frank Plummer, MD Hurlburt Auditorium, SPH, 12:00-1:00pm Professor of Medicine and Medical Microbiology, University of Manitoba; and Scientific Director March 13th General, National Microbiology Laboratory, Public iCAPTURE: Seminar Series Health Agency of Canada. The role of ABC transporters in sterol homeostasis - Peter A Edwards PhD Keynote Speaker 2009 PHCRI Research Day Gourlay Conference Room, SPH, 11:30-12:30pm Dr. Plummer is a leading specialist in HIV/AIDS research. During his 17 years in Nairobi, he discovered and studied a group of women who remained resistant to HIV despite repeated exposure

PHCRI RESEARCH EVENTS UPCOMING EVENTS MARCH 11: GAIRDNER MARCH 30: NIH INTERACTIVE LL ARE WELCOME TO ATTEND A MARCH 6: AIDS AWARENESS FOUNDATION SYMPOSIUM WORKSHOP NETWORK The Gairdner Foundation 50th Learn about the latest NIH updates, Dr Julio Montaner presents a talk th Anniversary Symposium is an funding priorities and eligibility of March 16 titled "HIV as a Chronic academic symposium featuring applicants from international iCAPTURE: Research in Progress Series Inflammatory Disease" at the Aids eight presenters, including four institutions. This session will include Imaging of Collagen Matrix Remodeling in Awareness Network Annual Speaker Nobel laureates (Drs. Carl Wieman, a discussion of the best approach to Three Dimensional Space Using Second Series.12:30-1:30pm Room 9660, Harold Varmus, Sydney Brenner and making a NIH application, online Harmonic Generation and Two Photon Blusson Hall, Faculty of Health Roger Tsien). For more information final submission updates and the Excitation Fluorescence – Thomas Abraham Sciences, . visit: http://www.events.ubc.ca/. NIH peer review process. 9am – Gourlay Conference Room, SPH, 9:00-10:00am For more information visit: 12om at Point Grey. To register: http://www.fhs.sfu.ca/news/events/ MARCH 11: DIABETES EVENT http://www.research.ubc.ca/EventVi March 20th aids-awareness-network-annual- CFRI, PHCRI and VCHRI present a ew.aspx?eventID=218 iCAPTURE: Seminar Series keynote-speaker free public talk titled "Navigating

Matters of Life and Death: Apoptosis, p53, and Diabetes Research - From Causes to Mitochondria - Douglas Green, PhD MARCH 10: ESSENTIAL TOOLS Care." Learn about research related Gourlay Conference Room, SPH, 11:30-12:30pm FOR BC HEALTH RESEARCHERS to diabetes and its complications from Dr. Bruce Verchere, CFRI; Dr. An update on the MSFHR Gordon Francis, PHCRI and Dr. March 23rd Technology/Methodology Platforms Garth Warnock VCHRI. 7- 9pm at 10am-12pm at the CFRI Chan iCAPTURE: Research in Progress Series the Chan Centre for Family Health Centre for Family Health Education. p63 regulates differentiation and adhesion of Education at BC Children’s Hospital. For more information contact: human airway epithelial cells: Implications for Register: 604-875-2000 ext. 5397 or [email protected] airway remodeling in asthma -Stephanie [email protected]. Warner Gourlay Conference Room, SPH, 9:00-10:00am

March 24th ANNOUNCEMENTS

Toastmasters GRANT SUCCESS For more information contact Jacqui Brinkman at [email protected] Congratulations to the following researchers and Gourlay Conference Room, SPH, 12:00-1:00pm teams for their operating grant funding success: Canadian Institutes of Health Research March 25th

CHEOS: Work in Progress Title: Stress and Growth over Time: Caregiving and Dr. George Browman Bereaved Parents of Children with Life-Limiting Hurlburt Auditorium, SPH, 12:00-1:00pm Illnesses. Co-Investigator: Lynn Straatman

March 27th Title: Canadian Cohort Obstructive Lung Disease iCAPTURE: Seminar Series (CanCOLD) Principal Investigator: Wan Tan Dr Edwin Morre Gourlay Conference Room, SPH, 11:30-12:30p BC Women’s Health Research Institute

March 30th Team: ICARE: Immigrant older women - Care Accessibility Research and Empowerment iCAPTURE: Research in Progress Series Defects in neoangiogenesis in CD34KO mice Principal Investigator: Sharon Koehn revealed in a Matrigel chamber model - Please contact us if you receive an award so that we can Heather Heine acknowledge your achievements: Gourlay Conference Room, SPH, 9:00-10:00am [email protected]

RESEARCH ETHICS BOARD PHC RESEARCH INSTITUTE CONTACTS APRIL DATES FOR FULL BOARD REVIEW VP Research & Academic Affairs Finance Manager Yvonne Lefebvre, PhD, x68903 Jo-Lynn Mervyn, x69146

Research Institute Accountant VP Executive Assistant PHC Research Institute REB Meeting Freda Liang, x63438 Gail Dibernardo, x69608 Office of Research Services th Friday, April 24, 2009 Research Accounts Bookkeeper 1190 Hornby Street, 11 Floor Vancouver, BC V6Z 2K5 Research Services Director Cindy Paddon, x62843 Submission Deadline* Meg Hughes, x69464 Ethics, Review Coordinator Office Hours: 8:00-4:00, M–F Friday, April 3, 4:00 pm Ethical Review Manager Christy Costello, x68567 T: 604-806-8567 Vivienne Bearder, x63496 F: 604-806-8568 * Submissions must be approved by the Grants and Contracts Coordinator W: http://www.providenceresearch.ca Department Head and entered in RISe by this Clinical Research Contracts Manager Gwen Sin, x69102 Esther Wu, x63199 E: [email protected] time. It is recommended that applications be Communications Coordinator Jennifer Kennedy x68175 sent to the Department Head at least 3 days in Human Resources Manager Kelly Ceron, x68570 advance of the submission deadline. fil

www.providenceresearch.ca April 2009

PHCRI RESEARCH EVENTS MESSAGE FROM YVONNE LEFEBVRE ALL ARE WELCOME TO ATTEND VP RESEARCH & ACADEMIC AFFAIRS April 3rd Economic conditions continue to have an impact on research iCAPTURE Seminar Series across Canada. April 1st marks the start of the new fiscal year MMPs as a target for treating aortic aneurysms – Tim Baxter and the research community in British Columbia is awaiting Gourlay Conference Room, SPH, 11:30am – announcements regarding funding for 2009/10. The good news 12:30pm is that the Michael Smith Foundation for Health Research (MSFHR) received $15 million as a line item in the 2009/10 April 3rd provincial budget. We are awaiting announcement of further Clinical Research Seminar Series funding as the MSFHR is in continuing discussions with the BC Dr. Peter Philips government to confirm 2009/10 funding before making Hurlburt Auditorium, SPH 12:00-1:00pm anticipated announcements about competitions and programs. April 6th These announcements will have powerful implications for the advancement of iCAPTURE: Research in Progress Series health research in BC. Global Properties of Signaling Networks in Virus-Infected Cardiomyocytes – Farshid S. The Research Institute is pleased to announce the launch of two new initiatives, an Garmaroudi online Researcher Directory and a Research Space Needs Study. Our directory is a Gourlay Conference Room, SPH, 9:00-10:00am comprehensive, searchable list of PHC researchers and is available on our website: PHC Researcher Directory. If you would like to make changes to your current profile April 7th or be added to our directory please contact [email protected]. The Toastmasters Club Research Space Needs Study is designed to create a common vision for research Contact [email protected] Gourlay Conference Room, SPH, 12:00 – 1:00pm space within our organization by aligning our three objectives of healthcare, education and research. The project will also help accelerate medical innovation by shortening the time between research, clinical application and educational April 8th dissemination of the latest advancements. CHEOS: Work in Progress Is Methadone Maintenance Treatment being Thank you to everyone who participated in PHCRI’s Research Day on March 9th. We optimized? Adherence to dosing guidelines in enjoyed celebrating the research achievements and advancements of the past year British Columbia: 1996-2007 - Bohdan Nosyk, with all of you. Special congratulations to Dr. Jim Russell who received the Research PhD Hurlburt Auditorium, SPH, 12:00-1:00pm and Mission Award. As part of UBC’s Celebrate Research Week, PHCRI also co- hosted an inter-institutional public event with Vancouver Coastal Health Research April 16th Institute and Children and Family Research Institute. The event focused on diabetes PHCRI Researchers Abroad Lecture research and featured Drs Gordon Francis, Garth Warnock and Bruce Verchere. Dr. Patricia Spittal Both events were well attended and we would like to thank everyone who was Hurlburt Auditorium, SPH, 12:00-1:00pm involved. -Yvonne Lefebvre

April 17th PHCRI RESEARCHER PROFILE iCAPTURE Seminar Series Quantitative proteomic analysis of Leishmania Sharon Koehn, PhD infantum membrane proteins in the search to Research Associate, Centre for Healthy Aging at identify potential drug targets – Miriam Providence; Adjunct Professor, Department of McAndrew Lynn Gourlay Conference Room, SPH, 11:30am- Gerontology, SFU; Research Affiliate, Centre for Aging, UVIC. 12:30pm Research Interests April 20th • Ethno-cultural minority older adults and iCAPTURE Research in Progress Series health The extracellular role of Granzyme B in abdominal aortic aneurysm and dissection – • Social and cultural dimensions of care Lisa Ang provision Gourlay Conference Room, SPH, 9:00-10:00am • Health care access and utilization

PHCRI RESEARCH EVENTS UPCOMING EVENTS

ALL ARE WELCOME TO ATTEND APRIL 16: PHCRI RESEARCHERS APRIL 20: BCCGN ANNUAL APRIL 23-26: CANADIAN ABROAD LECTURE SERIES CONFERENCE CONFERENCE ON HIV/AIDS RESEARCH April 21st Please join us as we highlight the The BC Clinical Genomics Network international-calibre research being is hosting its annual conference Toastmasters Club The 18th Annual Canadian conducted by researchers at focusing on the impacts of Conference on HIV/AIDS Research Contact [email protected] Providence Health Care. Speaker: genomics in the clinic, 8 am –5 pm, (CAHR 2009) will take place at the Gourlay Conference Room, SPH, 12:00 – 1:00pm Dr. Patricia Spittal, 12 – 1 pm, Plaza 500 Hotel, Vancouver BC. Westin Bayshore, Vancouver BC. To Hurlburt Auditorium, SPH. A light http://www.bccgn.ca/news- register visit: http://www.cahr- th April 24 lunch will be served. Please RSVP to events/events-education.htm acrv.ca/english/home/index.html iCAPTURE Seminar Series research @providencehealth.bc.ca APRIL 21: LIFESCIENCES BC Inadequate Protein Quality Control (PQC) in APRIL 23: UBC SCHOOL OF Heart Failure – Xuejun Wang ND INDUSTRY ROUNDTABLE APRIL 17: 2 ANNUAL BC NURSING SEMINAR Gourlay Conference Room, SPH, 11:30am- BIOLIBRARY WORKSHOP This Industry Roundtable titled "EU 12:30pm and Canadian Pharma Regulatory The UBC School of Nursing Critical This workshop titled "Patients as Updates – Clinical Trials and Hot Inquiry Seminar Series presents a st Partners In Personalized Medicine” May 1 Topics" will focus on European and talk by Dr. Colleen Varcoe titled will cover the role of biospecimens Clinical Research Seminar Series Canadian regulatory requirements "Research to Influence Policy: in research, ethics, privacy, public Modeling cigarette smoke induced COPD in for pharmaceutical clinical trials. Critical Conundrums". 12-1pm, 3rd confidence and patient advocacy. laboratory animals – Dr. Andrew Churg 8:30am-12:30pm, BC Showcase, 800 Floor UBC Hospital, 2211 Wesbrook 7:45am-4pm, Century Plaza Hotel, Hurlburt Auditorium, SPH 12:00-1:00pm Robson St. To register visit: Mall. For more information visit: Vancouver BC. RSVP to Sara Giesz at http://www.gifttool.com/registrar/S http://www.nursing.ubc.ca/Researc [email protected]. h/Research_Event_Calendar.htm th howEventDetails?ID=1367&EID=44 May 29 Society of Clinical Research Associates Exam 87 Registration deadline: April 17th http://www.socra.org/html/certific.htm APRIL 30 - MAY 2: CAREB- Children’s & Women’s Health Center of BC, ACCER NATIONAL CONFERENCE 8:00am- 12:00pm The 2009 Canadian Association of Research Ethics Boards conference is titled “Research Ethics In the 21st ANNOUNCEMENTS Century: Finding the Right Balance Between Principled and Perspective PHCRI ACHIEVEMENTS Approaches” Fairmont Hotel, Congratulations to the following researchers Vancouver BC. To register visit: and teams for their success: http://careb- 2009 LifeSciences BC Leadership Award accer.org/?q=/node/161

Dr Julio Montaner, Director of the BC May 21: Clinical Research Centre for Excellence in HIV/AIDS Education Event Publication: New England Journal of This presentation is titled “Assisting Medicine the Clinical Investigator: What the CMPA Wants You to Know”. Come Dr Peter Dodek – NICE SUGAR Study and learn directly from Robert Rivington, MD, FRCPC, of the Please contact us if you have information about Canadian Medical Protective PHC researchers and their recent achievements Association. 1:30 - 2:45 pm, New and we will acknowledge them in our next Lecture Theatre, SPH. To register: newsletter: [email protected] http://www.cheos.ubc.ca/news/wor kshop.php

RESEARCH ETHICS BOARD PHC RESEARCH INSTITUTE CONTACTS MAY DATES

FOR FULL BOARD REVIEW Human Resources Manager VP Research & Academic Affairs Kelly Ceron, x68570 Yvonne Lefebvre, PhD, x68903 PHC Research Institute REB Meeting Finance Manager VP Executive Assistant Office of Research Services Jo-Lynn Mervyn, x69146 th Friday, May 29, 2009 Gail Dibernardo, x69608 1190 Hornby Street, 11 Floor Research Institute Accountant Vancouver, BC V6Z 2K5

Freda Liang, x63438 Submission Deadline* Research Development Manager Meg Hughes, x69464 Office Hours: 8:00-4:00, M–F Friday, May 8, 4:00 pm Research Accounts Bookkeeper T: 604-806-8175 Ethical Review Manager Cindy Paddon, x62843 F: 604-806-8568

* Submissions must be approved by the Vivienne Bearder, x63496 W: http://www.providenceresearch.ca Grants and Contracts Coordinator Department Head and entered in RISe by this E: [email protected] time. It is recommended that applications be Clinical Research Contracts Manager Gwen Sin, x69102 Esther Wu, x63199 sent to the Department Head at least 3 days in Communications Coordinator Jennifer Kennedy x68175 advance of the submission deadline.

www.providenceresearch.ca May 2009

RESEARCH EVENTS MESSAGE FROM YVONNE LEFEBVRE ALL ARE WELCOME TO ATTEND VP RESEARCH & ACADEMIC AFFAIRS May 1 With a provincial election scheduled for May 12th the PHC A core question: The role of LCAT in the Research Institute is focused on a number of opportunities. central nervous system - Dr. Cheryl Wellington iCAPTURE Seminar Series Strategic partnerships and external relationships are essential tools Gourlay Conference Room, SPH, 11:30 AM for Research Institutes during these uncertain economic times. The Institute is working with the biotech and pharmaceutical May 4 industries towards striking partnerships that support research at IGTP relieves endoplasmic reticulum stress response induced by coxsackievirus B3 Providence. We are also working towards an affiliation agreement infection - Arthur Zhen Liu with Simon Fraser University to support its health research iCAPTURE Research in Progress Series initiatives and our researchers with appointments at SFU. Gourlay Conference Room, SPH, 9 AM

May 6 On the national level, the Canada Foundation for Innovation (CFI) Novel molecular strategies for HIV vaccine will be investing $600 million into infrastructure projects. In anticipation of funding design - Dr. Ralph Pantophlet announcements the Research Institute has launched a Research Space Needs Study. The BC-CfE Forefront Lecture goal of the study is to determine future research space and functional relationship Hurlburt Auditorium, SPH, 12 PM requirements for PHC's research programs. The Research Centres and the Department and May 8 Division Heads have been contacted in order to provide valuable data on how research Novel bronchodialator actions of anti- space is utilized and what their future needs will be. This project will result in a research inflammatory PPARγ ligands --- a one-stop space plan that will be invaluable as we prepare large institutional applications for treatment for asthma? - Dr. Jane Ward infrastructure awards like CFI. iCAPTURE Seminar Series Gourlay Conference Room, SPH, 11:30 AM On a provincial level, the Michael Smith Foundation for Health Research (MSFHR) is an May 11 integral support agency for health research in British Columbia. In 2009, the MSFHR will TBA - David Lin receive $30 million from the provincial government to support its programs. Academic iCAPTURE Research in Progress Series health science enterprises like Providence will benefit from the continued funding of the Gourlay Conference Room, SPH, 9 AM MSFHR personnel awards until the end of their term and the MSFHR institutional May 15 infrastructure and research unit awards have been extended until the end of March 2010. Abnormal calcium signaling and the pro- Future award competitions are expected in the coming months. We will keep you asthmatic phenotype of airway smooth muscle informed as these funding opportunities are announced. Dr. Stuart Hirst iCAPTURE Seminar Series As funding opportunities become more competitive our challenge will be to respond with Gourlay Conference Room, SPH, 11:30 AM high quality applications and research proposals. With a focus on research proposal May 22 development, the Research Institute will be offering a Grant Writing Workshop on June Muscle weakness in COPD. Causes, 25th in partnership with the MSFHR’s BCEOHRN Network. For more information or to consequences and treatments register, contact our Research Development Manager, Meg Hughes. Marc Decramer, PhD, MD 2009 Copland Lecture Series -Yvonne Lefebvre Gourlay Conference Room, SPH, 11:30 AM

May 25 PHCRI RESEARCHER PROFILE Thymic stromal lymphopoietin gene variant is associated with asthma and airway Larry Lynd, PhD hyperresponsiveness - Jianqing He Assistant Professor, Faculty of Pharmaceutical Sciences, iCAPTURE Research in Progress Series UBC; Associate Director, Collaboration for Outcomes Gourlay Conference Room, SPH, 9 AM Research and Evaluation (CORE) Scientist, CHEOS

May 29 HIV Infection in 2009-A Chronic Inflammatory Research Interests Disease - Dr. Julio Montaner • Quantitative risk-benefit analysis iCAPTURE Seminar Series Gourlay Conference Room, SPH, 11:30 AM • Pharmacoepidemiology and Health Economics • Using discrete choice experimentation to elicit preferences for treatment JUNE GRANT DEADLINES RESEARCH EVENTS

the BC-CfE. 8AM – 5PM, Sheraton MAY 5 & 19: TOASTMASTERS 01 June MAY 20: CHÉOS Health of the Homeless Panel Discussion Wall Centre. Gourlay Conf. Rm, SPH, 12–1 PM. Contact Jacqui Brinkman for info. CIHR Meeting, Planning and Dissemination CHÉOS presents a panel discussion MAY 26: PROOF Centre 2nd Grants with Mayor Gregor Robertson. 4PM, Annual Meeting JUNE 18: PHCRI Researchers Abroad New Lecture Theatre, SPH Lecture Series 8AM - 5PM, Sheraton Wall Centre. BC Mental Health and Addictions Research Please join us as we highlight the For more information email: Network Travel Bursaries MAY 21: What the CMPA wants international-calibre research being [email protected] you to know about conducting conducted by researchers at CIHR Team Grant – Environment and clinical research in Canada MAY 28: UBC Pathology Day Providence Health Care. Speaker: Dr. Reproductive Health – application deadline Organized by PHCRI and CHEOS, Poster and Oral presentations at the Thomas Kerr, 12 – 1 PM, Hurlburt come and learn directly from UBC Life Sciences Centre, 2350 Auditorium, SPH. Please RSVP to NIH Clinical Research Curriculum Award Robert Rivington, MD, FRCPC, of Health Sciences Mall. Cocktails & research @providencehealth.bc.ca the Canadian Medical Protective Dinner at the River Rock Casino JUNE 25: PHCRI Grant Writing Association about conducting 08 June Resort, Richmond BC. For more Workshop Clinical Research in Canada. 1:30 - information, contact Susana On June 25th the Research Institute will CIHR Emerging Team Grant: Co-morbidity of 2:45 PM, New Lecture Theatre, Martine [email protected] be offering a grant writing workshop at brain disorders and other health problems SPH. Please Register by May 19th: St. Paul’s Hospital. Please contact Meg www.cheos.ubc.ca/news/workshop MAY 29: SoCRA Exam Hughes for more information: 15 June .php The Society of Clinical Research [email protected] Associates exam will be held in MAY 25: BC-CfE 2009 Spring th. CIHR Institute of Gender and Health (IGH) Vancouver on May 29 For more HIV/Antiretroviral Update Travel Awards for Students and Post- information: Doctoral Fellows Open education event sponsored by www.socra.org/html/certific.htm

UBC Branch for International Surgery Research Grants: Surgical Care in Low ANNOUNCEMENTS AND ACHIEVEMENTS Resource Regions IMPACT Strategic Training Program grant Congratulations to the following 17 June renewed for six years at $1.95 Million researchers and teams for their success:

CIHR Emerging Team Grant: Alliances in Congratulations to the Providence Heart+Lung Mobility in Aging Institute’s Drs. Keith Walley, Peter Paré, David 2009 AccolAIDS Award for Science, Research & Granville and Ms. Jacqui Brinkman, on the Technology – BC Persons with AIDS Society

29 June successful renewal of CIHR funding for the Dr Mark Tyndall, BC Centre for Excellence in Integrated and Mentored Pulmonary and HIV/AIDS CIHR Emerging Team Grant: From Genes to Cardiovascular Training Strategic Training Program

Proteins, Cells, Tissues and Patients (IMPACT). 2009 – 2010 Heart and Stroke Foundation of

Providence’s nationally funded IMPACT award Canada Personnel Awards 2009 WorkSafe BC Systematic Reviews – RFP provides fellowships and training for both basic

and clinical science postdoctoral fellows at the Research Fellowship: BCEOHRN Research Capacity Development University of British Columbia and the University David Marchant: Matrixmetalloproteinases during Fund of Manitoba. Since its inception in 2003 the goal of • coxsackievirus induced myocarditis. Supervisor: the program is to create the next generation of Bruce McManus - iCAPTURE 30 June investigators capable of developing and translating Doctoral Research Award: knowledge from bench-to-bedside with the NSERC Steacie Fellowships outcome of improving cardiovascular-respiratory • Tse Yuan (Jerry) Wong: The role of serum response health status of the Canadian population. The factor in viral myocarditis. Supervisor: Honglin Luo Co-supervisor: Bruce McManus - iCAPTURE competition for renewal of this training program was extremely competitive and the renewal • Kristin Bowden: Cholesteryl ester storage disease as demonstrates it's impact on health research a model for understanding intracellular cholesterol homeostasis and HDL biogenesis. Supervisor: RESEARCH ETHICS BOARD training in Canada. Gordon Francis - iCAPTURE JUNE DATES PHC RESEARCH INSTITUTE CONTACTS For Full Board Review

REB Meeting VP Research & Academic Affairs Human Resources Manager PHC Research Institute Yvonne Lefebvre, PhD, x68903 Kelly Ceron, x68570 Friday, June 26 Office of Research Services VP Executive Assistant Finance Manager 1190 Hornby Street, 11th Floor Submission Deadline* Gail Dibernardo, x69608 Jo-Lynn Mervyn, x69146 Vancouver, BC V6Z 2K5 Friday, June 5, 4:00 pm Research Institute Accountant Research Development Manager Freda Liang, x63438 Office Hours: 8:00 AM–4:00 PM, M–F Meg Hughes, x69464 * Submissions must be approved by the T: 604-806-8567 Department Head and entered in RISe by this Research Accounts Bookkeeper Ethical Review Manager Cindy Paddon, x62843 F: 604-806-8568 time. It is recommended that applications be Vivienne Bearder, x63496 W: www.providenceresearch.ca sent to the Department Head at least 3 days in Grants and Contracts Coordinator E: [email protected] Clinical Research Contracts Manager Gwen Sin, x69102 advance of the submission deadline. Esther Wu, x63199 Communications Coordinator

Jennifer Kennedy x68175

www.providenceresearch.ca June 2009

RESEARCH EVENTS MESSAGE FROM YVONNE LEFEBVRE ALL ARE WELCOME TO ATTEND VP RESEARCH & ACADEMIC AFFAIRS June 1 As you know, research funding in Canada is undergoing some The effect of arginine vasopressin on challenges both politically and economically. Both the federal myocardial function after ischemia reperfusion injury --- Toonchai Indrambarya Canadian Institutes for Health Research (CIHR), Canada iCAPTURE Research in Progress Series Foundation for Innovation (CFI) and the provincial Michael Smith Gourlay Conference Room, SPH, 9-10AM Foundation for Health Research (MSFHR) are responding to the new funding reality with strategic plans for the next few years. All June 3 Dr. Patricia Spittal and Simone Carter three agencies are presently in the consultation phase and are CHEOS Work in Progress Seminar inviting feedback from Canada’s health research community. Hurlburt Auditorium, SPH, 12PM MSFHR CEO Dr John Challis presented a new strategic framework June 5 for health research in BC to the PHC research community on May Rho kinase inhibitors and statins: novel 27th. The discussion document has been posted on their website and the Foundation is therapeutical interventions in asthma? encouraging commentary from the research community across BC. I encourage all of you Dedmer Schaafsma, PhD to send MSFHR your comments: www.msfhrstrategicplan.org. iCAPTURE Seminar Series Gourlay Conference Room, SPH, 11:30AM Nationally, the CIHR has posted its draft strategic plan on its website. The “Health June 8 Research Roadmap 2009-14” will guide the institutes through these uncertain times. CIHR Small airway obstruction in COPD President Dr. Alain Beaudet has invited the Canadian health research community to share John McDonough their input on the draft plan before June 12th: www.cihr.ca/e/39188.html. Also on the iCAPTURE Research in Progress Series national funding scene, the CFI received $600 million in the 2009-10 federal budget. Last Gourlay Conference Room, SPH, 9-10AM month the CFI invited consultation from the Canadian research community in order to June 12 inform its strategic plan. Resulting from the recent consultation process, a funding Epithelial regulators of eicosanoid production competition announcement is expected before the end of the year: in asthma --- Teal S. Hallstrand, MD www.innovation.ca/en/news?news_id=129 iCAPTURE Seminar Series Gourlay Conference Room, SPH, 11:30 AM The economic downturn has had a substantial impact on local foundations. The Vancouver Foundation has cancelled their 2009 health research competition. This is a June 15 Data and knowledge modeling in support of worrisome example of the erosion of health research funding as charities and donors make clinical research --- Soroush Samadian difficult decisions on how best to invest reduced resources. As research funds become iCAPTURE Research in Progress Series scarce, the quality of grant applications needs to improve. The Research Institute is Gourlay Conference Room, SPH, 9-10AM offering a Grant Writing Workshop on June 25th. June 17 A quick update on the Research Space Needs Study: In May the project focused on Dr. Rob Stenstrom meetings with the research centres and the Hospital division and department heads. A CHEOS Work in Progress Seminar draft report will be circulated in June to the stakeholders and meetings will be held Hurlburt Auditorium, SPH, 12PM providing an opportunity for discussion and consultation on the recommendations. June 19 Environmental factors disrupting thyroid -Yvonne Lefebvre hormone function --- How frogs in your backyard can contribute to heart and lung PHCRI RESEARCHER PROFILE health --- Dr. Caren Helbing iCAPTURE Seminar Series Jagbir Gill, MD, FRCPC Gourlay Conference Room, SPH, 11:30AM Transplant Nephrologist, PHC; Assistant Professor of June 26 Medicine, Department of Medicine, UBC; Research Allergen inhalation challenge: A model to Scientist, CHEOS; St. Paul’s Hospital Foundation assess mechanisms of asthma and novel Physician Scholar Awardee therapies - Gail Gauvreau iCAPTURE Seminar Series Gourlay Conference Room, SPH, 11:30 AM Research Interests • Clinical outcomes in kidney transplant recipients • Deceased organ donation • Transplant tourism UPCOMING GRANT RESEARCH EVENTS DEADLINES JUNE 4: CIP Research Day 2009 Professionals course is designed to JUNE 18: PHCRI Researchers provide an overview of GCP. Abroad Lecture Series June 18 The UBC Clinician Investigator Location: QLT 887 Great Northern Vancouver Foundation Grant Cycle Program (CIP) in collaboration with Way. Registration Link Please join us for lunch as we the iCAPTURE CIHR/HSFC IMPACT highlight the international-calibre July 3 Strategic Training Program presents research being conducted by Emerging Team Grant: Alliances in Mobility the 8th Annual CIP Research Day JUNE 17: LifeSciences BC researchers at Providence. in Aging 2009. Gourlay Conference Room, St. Breakfast Speaking Series Speaker: Dr. Thomas Kerr, Paul’s Hospital from 1-6PM. For “Life Sciences Innovation and 12–1 PM, Hurlburt Auditorium. July 15 information, contact Tessa Feuchuk. Commercialization; Creating Better See poster below for details. DoD Prostate Cancer Pathology Resource Health and Better Wealth for B.C.” Registration Link Network Awards JUNE 8-9: CDRD Conference Featuring Dawn Graham, President, Merck Frosst Canada. 7:30-9:30AM, “Charting the Course to JUNE 25: PHCRI Grant Writing July 20 Fairmont Waterfront Hotel. Commercialization: CDRD's Workshop CIHR Emerging Team Grant: HIV/AIDS Registration Link Inaugural Conference on Drug th Vaccine Discovery and Social Research - LOI On June 25 the PHCRI and the BC Research & Development.” Environmental and Occupational JUNE 24: Population Data BC July 31 Registration Link Health Research Network (BCEOHRN) BCRRHRN Conference Travel Bursary Special Presentation will be offering a grant-writing JUNE 15-16: LifeSciences BC Dr Morris Barer, Director, Centre for workshop at St. Paul’s Hospital. For Faculty of Medicine CFI Leaders Opportunity GCP Workshop Health Services and Policy Research information contact Meg Hughes. Fund The Good Clinical Practice (GCP) presents a health services research

Survival Skills for Clinical Research overview. For more information August 17 contact Mary Luk. The Lawson Foundation Diabetes Funding Opportunity ANNOUNCEMENTS AND ACHIEVEMENTS JUNE LUNCH and LEARN EVENTS Dr. Sam Wiseman, selected as one of Canada's Top 40 Under 40 TM June 2- Toastmasters Congratulations to Dr. June 11- Tillie Hackett: Taking charge of your Sam Wiseman, St. Paul's summer research training Hospital general surgeon and research scientist June 16- Toastmasters with the Genetic Pathology Evaluation June 23- Dr. David Walker: Reflections upon Centre. Dr. Wiseman is a being a graduate student: Stories from 7 recipient of a Canada's years of graduate advising Top 40 Under 40TM Award for 2009. June 25- Dr. Bruce McManus: Careers in Science Canada's Top 40 Under 40TM is a prestigious national award program, which annually honours 40 These events will be held in the Gourlay Canadians in the private, public and not-for-profit Conference Room, SPH, 12–1PM. For more sectors under the age of 40. Designed to promote information contact Jacqui Brinkman professional development, mentorship, and awareness, Canada's Top 40 Under 40TM introduces RESEARCH ETHICS BOARD leaders to the business community and the general public, and promotes them as role models for other AUGUST DATES aspiring young Canadians. For Full Board Review REB Meeting PHC RESEARCH INSTITUTE CONTACTS Friday, August 28

Submission Deadline* VP Research & Academic Affairs Human Resources Manager Yvonne Lefebvre, PhD, x68903 Kelly Ceron, x68570 Office of Research Services

Friday, August 7, 4:00 pm 1190 Hornby Street, 11th Floor VP Executive Assistant Finance Manager * Submissions must be approved by the Gail Dibernardo, x69608 Jo-Lynn Mervyn, x69146 Vancouver, BC V6Z 2K5 Department Head and entered in RISe by this Research Institute Accountant Research Development Manager Freda Liang, x63438 time. It is recommended that applications be Meg Hughes, x69464 Office Hours: 8 AM–4 PM, M–F

sent to the Department Head at least 3 days in Research Accounts Bookkeeper T: 604-806-8567 advance of the submission deadline. Ethical Review Manager Cindy Paddon, x62843 F: 604-806-8568 Vivienne Bearder, x63496 Grants and Contracts Coordinator E: [email protected] Clinical Research Contracts Manager Gwen Sin, x69102 W: www.providenceresearch.ca Note: there is no REB meeting Esther Wu, x63199 Communications Coordinator held in July Jennifer Kennedy x68175

www.providenceresearch.ca July/ August 2009

RESEARCH EVENTS MESSAGE FROM YVONNE LEFEBVRE ALL ARE WELCOME TO ATTEND VP RESEARCH & ACADEMIC AFFAIRS July 7 Where does the time go? Canada Day marks the official start of Toastmasters Club --- Jacqui Brinkman summer across Canada. It also marks the transition from one Professional Development Series Gourlay Conference Room, SPH, 12-1PM academic year to the next. July 9 Each year the University of British Columbia compiles an annual Unlocking the Virtual Library; Getting Started summary of research awards. Research activity at Providence on Library Research --- Barbara Saint continues to grow annually thanks in large part to the efforts of so Professional Development Series many investigators and their teams. One area of research funding Gourlay Conference Room, SPH, 12 - 1PM that has not seen an increase over the past few years is clinical July 14 trials. Across UBC's teaching hospitals there has been a trend of Scientific Poster Presentations - Pascal decreasing numbers of clinical trials. Bernatchez and Jennifer Myers Professional Development Series In an effort to better support PHC's clinical researchers the Centre for Health Evaluation Gourlay Conference Room, SPH, 11AM -12PM and Outcome Sciences (CHEOS) is offering a new service through a Clinical Trials Support Unit (CTSU). The mandate of the CTSU is to facilitate and assist with the development of July 16 Genapha Tools and Applications for clinical trials. If you are developing a clinical trial protocol, visit the CHEOS website for Respiratory Researchers - Denise Daley, David more information on the services they provide: www.cheos.ubc.ca. To improve PHC Zamar, and Ben Tripp research quality the CTSU will also offer clinical research education to clinical investigators Professional Development Series and their research personnel. Information about the training and development programs Gourlay Conference Room, SPH, 12 - 1PM will be made available in the fall. July 21 I wanted to take a moment to acknowledge a special member of the research community Toastmasters Club --- Jacqui Brinkman at Providence. Martha Mackay is a Clinical Nurse Specialist who has recently been awarded Professional Development Series Gourlay Conference Room, SPH, 12 - 1PM a prize for her essay on "Why Nursing Has Not Embraced the Clinician-Scientist Role". Mackay observes, “The nurse clinician-scientist role holds promise for making strides in July 23 clinically relevant research, and for accelerating the knowledge cycle from clinical problem Being a Physician Scientist - Gordon Francis to research question to change in clinical practice”. PHC wants to promote and foster this Professional Development Series Gourlay Conference Room, SPH, 12 - 1PM interest and opportunity. July 28 The Office of Research Services welcomes Nesa Khareghani to the role of Manager of Pre Toastmasters Club --- Jacqui Brinkman and Post Review. She brings experience to this role from working with the Clinical Professional Development Series Research Ethics Board at Vancouver General Hospital. Gourlay Conference Room, SPH, 12 - 1PM The Research Institute has lots of exciting programs planned for the fall and we look For more information on any of the above listed forward to seeing you all then. Have a wonderful summer everyone. professional development events please contact Jacqui Brinkman at [email protected] -Yvonne Lefebvre

RESEARCH ETHICS BOARD PHCRI RESEARCHER PROFILE

AUGUST DATES Martha Mackay, MSN, RN, CCN(C) For Full Board Review Clinical Nurse Specialist, Cardiology Heart Centre, St. REB Meeting Paul's Hospital; CIHR Clinical Research Fellow Doctoral Candidate, UBC School of Nursing Friday, August 28

Submission Deadline* Research Interests Friday, August 7, 4:00 pm • Risk factor interventions for hospitalised cardiac *Submissions must be approved by the Department patients Head and entered in RISe by this time. It is • Treatment-seeking behaviour of acute coronary recommended that applications be sent to the syndromes patients Department Head at least 3 days in advance of the Gender differences in symptoms of acute submission deadline. • coronary syndromes UPCOMING GRANT RESEARCH EVENTS DEADLINES JULY 7: BCCfE Forefront Lecture hosting the GxP Compliance: Audits Heart + Lung Research Institute's vs. Inspections Workshop this Undergraduate Summer Student The BC Centre for Excellence in July 17 summer. To register please visit: Research Day. St. Paul's Hospital HIV/AIDS forefront lecture series R&D Collaboration with China - EOI http://www.gifttool.com/registrar/S Conference Centre. Preliminary presents a talk by Dr. Alan howEventDetails?ID=1367&EID=49 abstracts are due Friday, July 24. For Whiteside called "Is AIDS Still July 22 74. 8:30AM - 4:30PM, BCIT more information contact Saranee Exceptional?" Alan Whiteside, D American Heart Association National Clinical Downtown Campus, 555 Seymour Fernando: [email protected]. Econ, is a professor of economics Research Program Street, Vancouver, BC. and director of the Health AUGUST 18-20 CIHR --- KT Canada Economics and HIV/AIDS Research July 31 JULY 16: LifeSciences BC Wireless Summer Institute Division (HEARD) at the University Stemmler Fund Grant Awards – LOI Health Forum of KwaZulu- Natal in Durban, South The purpose of the Knowledge Explore the opportunities for Africa. 12:00PM, New Lecture Translation Canada Summer Institute BCRRHRN Conference Travel Bursary Wireless Health in BC. To register: Theatre, St. Paul’s Hospital. For more is to provide participants with the http://whf2009.eventbrite.com/. information contact Peter Vann at opportunity to increase their Faculty of Medicine CFI Leaders Opportunity 7:30AM - 10:00AM, Sutton Place 604-806-8549. understanding of knowledge Fund Hotel - Versailles A, 845 Burrard translation research as well as

Street, Vancouver, BC. opportunities and challenges in this August 1 JULY 6-8: LifeSciences BC/BCIT field. Applications are due July 7th. For NSERC Discovery Grants Program Workshop AUGUST 18: HLI Undergraduate an application form and more

Bridging Academics with Industry... Summer Student Research Day information visit: ktclearinghouse.ca August 4 The British Columbia Institute of Canadian Cystic Fibrosis Foundation: Undergraduate student researchers Technology, with support from Research Grants - NOI from all PHCRI Centres are welcome LifeSciences British Columbia, is to participate in the Providence August 7 RFIQ: Studies of Long-Term Exposure to Air Pollution and Chronic Cardiovascular and ANNOUNCEMENTS AND ACHIEVEMENTS Respiratory Disease in Asia Providence Health Care's 2008-09 Annual UBC FoM Canadian Research Chairs Tier II August 11 Report Now Available Competition IRSST Collaborative Activity Grant “Building Partnerships for Life” PHC’s 2008-09 The Faculty of Medicine has 4 CRC Tier II chairs Annual Report tells the Providence Story. Visit: available in this competition. The closing date: is August 17 www.providencehealthcare.org to download a September 1, 2009. For application forms The Lawson Foundation Diabetes Funding printable PDF file of PHC's 2008-2009 Annual (UPDATED) and more information please visit: Opportunity Report. www.med.ubc.ca

Congratulations to Dr. Jim Russell August 31: 2010 Canada Gairdner Global Health Award 2010 Wolf Prizes in the Sciences: Call for Click here to view a video of PHCRI Researcher Dr. The long-term goal of this prize is to reward and Nominations Jim Russell, Research and Mission Award winner, stimulate members of the global scientific and

from this year’s PHC Annual General Meeting medical community to undertake research that will WSIB Research Advisory Council - RFP lead to advances valuable to the health of nations. CIHR Knowledge Translation Learning For nomination details please see attached form or International Myeloma Foundation Research Modules visit: www.gairdner.org Grants Three CIHR knowledge translation online learning Nominations for 2010 should be received no

modules are now available: later than October 1, 2009 Non-communicable Chronic Diseases - A Guide to Researcher and Knowledge User PHCRI Grant Writing Workshop – Recording Research Training Program Collaboration in Health Research - Introduction to Evidence-Informed Decision If you were unable to attend our recent grant NIH Ancillary Studies in Clinical Trials Making writing workshop and would like to listen to the - Critical Appraisal of Intervention Studies WebEx recording of the workshop please visit: September 1 Visit: http://www.cihr-irsc.gc.ca/e/38766.html https://msfhr.webex.com/msfhr/lsr.php?AT=pb&SP Heart and Stroke Foundation – Grant-in-Aid =MC&rID=33579747&rKey=faca55e6c49633b8 and Personnel Awards PHC RESEARCH INSTITUTE CONTACTS CIHR Operating Grant: Aboriginal Health Intervention VP Research & Academic Affairs Human Resources Manager Yvonne Lefebvre, PhD, x68903 Kelly Ceron, x68570 PHC Research Institute

Office of Research Services ATS Foundation Tobacco-Dependence Finance Manager VP Executive Assistant 1190 Hornby Street, 11th Floor Research Fund Grants Gail Dibernardo x69608 Jo-Lynn Mervyn, x69146 Vancouver, BC V6Z 2K5 Research Development Manager Research Institute Accountant CIHR Canada-UK Aging Initiative (2009) Meg Hughes, x69464 Freda Liang, x63438 Office Hours: 8:00 AM–4:00 PM, M–F Ethical Review Manager Research Accounts Bookkeeper T: 604-806-8175 CIHR Proof of Principle: Phase I and Phase II Vivienne Bearder, x63496 Cindy Paddon, x62843 F: 604-806-8568 W: www.providenceresearch.ca Clinical Research Contracts Manager Grants and Contracts Coordinator E: [email protected] September 2 Esther Wu, x63199 Gwen Sin, x69102

CIHR Catalyst Grant: Health Equity Pre and Post Review Manager Communications Coordinator Nesa Khareghani x68567 Jennifer Kennedy x68175

www.providenceresearch.ca September 2009

RESEARCH EVENTS MESSAGE FROM YVONNE LEFEBVRE ALL ARE WELCOME TO ATTEND VP RESEARCH & ACADEMIC AFFAIRS Welcome back everyone. Labour Day always marks the start of a September 8 & 22 new academic year and a busy month for grant applications. Many Toastmasters Club of the large funding agencies including the CIHR and the Heart & Jacqui Brinkman Stroke Foundation have September deadlines. Good luck to all Professional Development Series applicants with this fall round of funding competitions. Gourlay Conference Room, SPH, 12-1 PM With the start of a new academic year, research at Providence continues to grow. Researchers at Providence attracted September 10, 17 & 24 over $32.4 million in external research funding in 2008/09. This Pulmonary Pathophysiology represents 11% increase over last year. Research at PHC represents PATH 518- MEDICINE 560 7% of all research conducted at the University of British Columbia Jacqui Brinkman and 13% of research conducted by the Faculty of Medicine. Most Gourlay Conference Room, SPH, 1:30 – 3 PM impressive, the percentage of awards that resulted from competitive, peer-reviewed competitions has increased to 73%. This statistic speaks to the high quality of research September 16 being conducted across Providence Health Care. Let’s Talk About Breast Cancer --- Current A special note of congratulations to the NAOMI research team. The results of Concepts in Diagnosis and Management their research were published in the New England Journal of Medicine. The CIHR-funded Drs Urve Kuusk & Nancy van Laeken NAOMI clinical trial was conducted in Vancouver and Montreal. This important work will St Paul’s Hospital Community Forums be continued by Dr Michael Krausz’s team with the “Study to Assess Longer-term Opioid New Lecture Theatre, SPH, 7-9 PM Medication Effectiveness” (SALOME) project which has received CIHR funding for the next September 16 three years. Applying Indirect Comparisons of Thank you to everyone who participated in the Research Space Needs Study. Randomized Trials. Moving Meta-analysis The project was the first research space study conducted at PHC to include the major Beyond Pooled Estimates research centres and the clinical research programs in its scope. The consultant will be Edward Mills, University of Ottawa releasing a final report this month and this important document will help to inform our Canada Research Chair in Global Health research space planning for the next 3-5 years. CHEOS Work In Progress Series As you are aware, the Provincial Health Authorities are facing significant budget Hurlburt Auditorium, SPH, 12-1 PM shortfall. The CEO’s of Providence and the Lower Mainland Health Authorities (VCHA, PHSA, FHA) are working together on a plan to consolidate support services and find September 30 efficiencies to avoid impacting clinical service delivery to the public. While research has The USAID-AMPATH Partnership: not been included yet in the review process, efficiency and reducing duplication of service Translating Public Health Research into is something that we should strive for across our programs. Public Health Action in Western Kenya The Research Institute has a busy year ahead and is offering a series of new Dr. Paula Braitstein, Indiana University research skill building workshops and expanding on strategic initiatives for the Providence BC CfE Forefront Lecture Series research community. We look forward to working with you to continue to advance Hurlburt Auditorium, SPH, 12-1 PM research across Providence. -Yvonne Lefebvre

PHCRI RESEARCHER PROFILE RESEARCH ETHICS BOARD SEPTEMBER DATES Don Sin, MD, FRCPC For Full Board Review Associate Head of Research, UBC/SPH Dept of Medicine Associate Professor, Respiratory Medicine, UBC Next REB Meeting Canadian Research Chair in Chronic Obstructive Friday, September 25 Pulmonary Disease (COPD)

Submission Deadline* Research Interests Friday, September 4, 4:00 PM • Identifying novel biomarkers to predict morbidity *Submissions must be approved by the Department and mortality in COPD Head and entered in RISe by this time. It is recommended that applications be sent to the Department Head at • Molecular and epidemiological links between COPD, least 3 days in advance of the submission deadline. lung cancer and cardiovascular disease • Understanding increased risk for COPD in women UPCOMING GRANT & RESEARCH EVENTS & WORKSHOPS AWARD DEADLINES Hospital, 7:00-9:00. To register call 604- OCTOBER 1: 806-8495 E-mail: Communicating Through Conflict: [email protected] OCTOBER 1 A People Skills Workshop for

Research Teams UBC: Exploratory Workshop Grant- SEPTEMBER 29: Interpersonal communication skills are Peter Wall Institute for Advanced So! It’s Time to Write a Paper: essential in the workplace. This workshop Studies aims to enhance participants’ awareness A Series of Manuscript Writing Workshops and practice of effective interpersonal UBC: Martha Piper Fund communication skills. Participants will gain A series of three workshops on preparing an ability to better manage working SEPTEMBER 16: research proposals and papers for Gairdner Foundation: Wightman Award relationships for successful research teams. publication will be held at St. Paul’s St. Paul’s Hospital Community This workshop will be instructed by Sally Hospital on September 29, October 22 Gairdner Foundation: Global Health Forums: Let’s Talk about Breast Halliday, Managing Director of the UBC Life Cancer: Current Concepts in and November 10th. Register early as Awards and Career Centre. The workshop will be Diagnosis and Management space is limited to 25 registrants per held in the St. Paul's Hospital Conference workshop. These workshops will be Gairdner Foundation: International Join Drs Urve Kuusk and Nancy Van Centre from 12- 4:30 PM. Registration fee instructed by Dr Iain Taylor, UBC Awards Laeken for a talk about breast cancer $70. To register visit: Professor Emeritus. diagnosis and surgical management of www.cheos.ubc.ca/news/index.php?page=w For more information or to register, the disease. Presented by the orkshop§ion=wips8id=23 Burroughs Wellcome Fund: Career contact Jacqui Brinkman: Departments of Medicine and Surgery For more information contact Meg Hughes: Awards for Medical Scientists [email protected] and the St. Paul’s Hospital Foundation. [email protected]

New Lecture Theatre, St Paul’s OCTOBER 15 ANNOUNCEMENTS AND ACHIEVEMENTS UBC: Charles A McDowell Award for Excellence in Research Providence’s researchers and their Congratulations to summer student teams attract $32.4 million in external research day awardees. UBC: Killam Research Prizes research funding in 2008/09. On August 18th, the Heart+Lung Institute celebrated its Research at Providence Health Care (PHC) has grown undergraduate students with a special research day at St. UBC: Jacob Biely Faculty Research Prize steadily over the past few years. In 2000/01, PHC Paul’s Hospital. researchers attracted $11.1 million in external Awards were presented to students for best overall oral Canadian Society for Clinical research award funding. In 2008/09 PHC's external presentations, and best poster in cardiovascular and Investigation Distinguished Service research award funding grew to over 32.4 million. This pulmonary & technology. Congratulations to all the Award is an incredible achievement and represents a 200% awardees: Grace Yang, Andy Trane, Simone Thair, Karl increase in research activity across Providence. Heilbron, Jolina Carson, Stefanie Mak, Nathan Wong, OCTOBER 30 Sarah Pazooki, Cheryl Lane, Liam Russell, Terence Yung and Julie Man. PHCRI Annual Research Funding Fullbright New Century Scholar Awards 40

35 33.4 27.6 30 27.4 29.1 22.9 23.4 CIHR Catalyst Grant: Post Market Drug 25 21.6 16.7 Safety and Effectiveness Registration 20 19.2 15 11.1 deadline: September 25th 10 Total Funding Funding (M$) Total 5 0 NOVEMBER 2* 00/01 01/02 02/03 03/04 04/05 05/06 06/07 07/08 08/09 SAVE THE DATES: Fiscal Year MARCH 8th = PHC Research Day 2010 CIHR Operating Grant: HIV/AIDS MARCH 9th= Heart+Lung and Blood Fest 2010 (Community-Based Research)*Registration deadline: October 1st PHC RESEARCH INSTITUTE

CIHR Catalyst Grant: HIV/AIDS VP Research & Academic Affairs Human Resources Manager (Community-Based Research) Yvonne Lefebvre, PhD, x 68903 Kelly Ceron, x 68570 PHC RESEARCH INSTITUTE Office of Research Services Finance Manager *Registration deadline: October 1st VP Executive Assistant Gail Dibernardo x 69608 Jo-Lynn Mervyn, x 69146 1190 Hornby Street, 11th Floor CIHR Operating Grant: Innovations in Research Development Manager Research Institute Accountant Vancouver, BC V6Z 2K5 Meg Hughes, x 69464 Freda Liang, x 63438 Health Research *Registration deadline: st Ethical Review Manager Research Accounts Bookkeeper Office Hours: 8:30 AM–4:00 PM, M–F October 1 Vivienne Bearder, x 63496 Cindy Paddon, x 62843 T: 604-806-8175 Clinical Research Contracts Manager Grants and Contracts Coordinator F: 604-806-8568 Questions about funding opportunities? Esther Wu, x 63199 Gwen Sin, x 69102 W: www.providenceresearch.ca

Contact: Meg Hughes, Research Pre and Post Review Manager E: [email protected]

Development Manager, PHCRI Nesa Kruse, x 68567

www.providenceresearch.ca October 2009

RESEARCH EVENTS MESSAGE FROM YVONNE LEFEBVRE ALL ARE WELCOME TO ATTEND VP RESEARCH & ACADEMIC AFFAIRS October 6 & 20 October is here and as usual, fall marks a time for change. Not only Toastmasters Club-everyone welcome is there change in the colour of the leaves but there is change in Gourlay Conference Room, SPH, 12-1 PM health infrastructure funding in BC. Provincial funding for health Contact: [email protected] research has been impacted significantly as illustrated by the Michael Smith Foundation for Health Research’s announcement of October 1, 8, 15, 22 & 29 early termination of its infrastructure funding programs. This is Pulmonary Pathophysiology Lectures having a significant impact on many programs including research PATH 518- MEDICINE 560 units, health population networks, universities and the academic Gourlay Conference Room, SPH, 1:30 – 3 PM health science centres.

October 7 MSFHR CEO Dr John Challis has asked the BC health research Determining HIV Related Vulnerabilities community to write letters to the Premier and the Health Minister demonstrating the Among Conflict-affectd Populations in importance of investing in the health research community through the MSFHR. See page Gulu and Amuru District Northern two for details on how to participate in the letter campaign. We have provided a template Uganda letter the Faculty of Medicine has suggested researchers personalize with their own case Sheetal Patel for support of the Foundation. CHEOS Work in Progress Hurlburt Auditorium, SPH, 12–1 PM On a more positive note, we continue to celebrate research success and celebrity with the Research Institute’s Researchers Abroad lecture series. Please join us on Wednesday, October 14 October 21st to hear from Dr Janet McElhaney, Head of UBC and VGH Division of Geriatric Doing Time: A Time for Incarcerated Medicine and the Allen M. McGavin Chair in Geriatrics Research, UBC. Dr McElhaney will Women to Develop a Health Action present research surrounding designing effective influenza vaccines for an aging Strategy population. A light lunch will be served and space is limited for this event due to the Patti Janssen exciting nature of the speaker so please register early by e-mailing: CHEOS Work in Progress [email protected]. Hurlburt Auditorium, SPH, 12-1 PM October 21 And finally on a personal note, I wanted to acknowledge one of the original members of Rational Design of Influenza Vaccines for the Research Institute team who is leaving Providence. Meg Hughes has been involved in Older Adults: Beyond Antibody Responses the establishment of the PHC Research Institute since its inception in 2004. She has been a Janet McElhaney key leader in the reorganization of the Office of Research Services and the Knowledge PHCRI Researchers Abroad Cycle Office. Please join me in wishing her well in her new role at the Child & Family Hurlburt Auditorium, SPH, 12-1 PM Research Institute. -Yvonne Lefebvre October 27-29 PHCRI RESEARCHER PROFILE Wounded Souls and the Vulnerable Self, Trauma and Addiction Richard Harrigan, PhD Michael Krausz Director, Research Labs, BC Centre for Excellence in International Workshop on Addictions HIV/AIDS UBC Campus, First Nations Longhouse Associate Professor, Division of AIDS, UBC

RESEARCH ETHICS BOARD Research Interests OCTOBER DATES -Novel and cost-effective laboratory tests to monitor HIV For Full Board Review progression Next REB Meeting -Strategies for the measurement and prevention of drug Friday, October 30 resistance Submission Deadline* -Laboratory based tools to detect and monitor drug adherence Friday, October 9, 4:00 PM -Relationships between human and viral genetic factors and treatment outcomes *Submissions must be approved by the Department Head and entered in RISe by this time. It is recommended that applications be sent to the Department Head at least 3 days in advance of the submission deadline. UPCOMING GRANT & RESEARCH EVENTS & WORKSHOPS AWARD DEADLINES OCTOBER 21: Head of UBC and PHC Divisions of surgical management of the disease. Endocrinology; Thursday, October 21, Presented by the Departments of Medicine PHCRI Researchers Abroad: NOVEMBER 1 2009, 12:00 – 1:00 PM To register, E-mail: and Surgery and the St Paul’s Hospital Rational Design of Influenza [email protected] . Foundation. Vaccines for Older Adults: Beyond Linus Pauling Institute Prize for Health New Lecture Theatre, St Paul’s Hospital, Antibody Responses 7:00-9:00. Register e-mail: Research [email protected] .

NOVEMBER 2* OCTOBER 22:

Manuscript Writing Workshops CIHR Operating Grant: HIV/AIDS (Community-Based Research) So! It’s Time to Write a Paper *Registration deadline: Oct. 1st A series of workshops on preparing research proposals and papers for publication will be CIHR Catalyst Grant: HIV/AIDS held at St Paul’s Hospital on October 22nd (Community-Based Research) OCTOBER 21: and November 10th. Register early as space

*Registration deadline: Oct. 1st St. Paul’s Hospital Community is limited to 25 registrants per workshop. This special event is designed to bring Forums These workshops will be instructed by researchers from all over Providence Dr Iain Taylor, UBC Professor Emeritus. For CIHR Operating Grant: Innovations in Steering Clear of the F-Words This together to highlight the research of more information or to register, contact Health Research international renown being conducted Winter-Flu and Falls *Registration deadline: Oct. 1st Jacqui Brinkman: by PHC Research Institute researchers. Join Drs Janet McElhaney and Wendy [email protected] Our speaker will be Dr Janet McElhaney, Cook for a talk about diagnosis and NOVEMBER 6

Ca na da’s Top 40 Under 40 ANNOUNCEMENTS AND ACHIEVEMENTS

Heart and Stroke Foundation of MSFHR encourages BC health research New Fellowship to train world’s best vitreo- Ca na da-Jump Start Resuscitation community to communicate the value of retinal specialists the MSFHR to the Government of BC Former EnCana Corp. CEO Gwyn Morgan, and his wife, NOVEMBER 14 MSFHR CEO Dr John Challis is encouraging the community leader Patricia Trottier, have donated $1.375 research community for their help by sending letters million to St Paul’s Hospital Foundation in honour of B.C. Lung Association – National Grant to the provincial political leaders to demonstrate the Providence Health Care vitreo-retinal surgeon, Dr William Review Process value of the MSFHR: H Ross. Morgan and Trottier were inspired to give after BC Premier Campbell Dr Ross saved Morgan’s sight. The commitment from the NOVEMBER 16 [email protected] Gwyn Morgan and Patricia Trottier Foundation has BC Health Minister Falcon created the William H Ross Fellowship in Vitreo-Retinal Association of Faculties of Medicine of [email protected] Excellence to train the world’s best vitreo-retinal Ca na da A wards BC Health Critic Adrian Dix specialists at St Paul’s and UBC for the next 25 years. [email protected] Ca na da/U.S. Fulbright Scholar Award In your support letter, it is important to thank the The first William H Ross Vitreo-Retinal Fellow, Dr Andrew government for its MSFHR funding of $15 million Kirker, is currently training under Dr Ross and other NOVEMBER 26 during these tough economic times. Add a personal retinal specialists affiliated with UBC. story demonstrating the impact the MSFHR has had For more information about this fellowship, visit Ca na dian Society for Clinical in your research area if possible. The goal of the campaign is to demonstrate the opportunity to build www.helpstpauls.com Investigation Distinguished Scientist our health research capacity through continued and Lecture Award and Joe Doupe Young sustained funding by the provincial government. Investigator Award

NOVEMBER 30

PHC RESEARCH INSTITUTE Ca na dian Medical Association Awards

VP Research & Academic Affairs Pre and Post Review Manager Yvonne Lefebvre, PhD, x 68903 Nesa Kruse, x 68567 PHC RESEARCH INSTITUTE DECEMBER 1 Office of Research Services VP Executive Assistant Human Resources Manager Gail Dibernardo x 69608 Kelly Ceron, x 68570 th Royal Society of Cana da – 1190 Hornby Street, 11 Floor Flavelle Medal and McLaughlin Research Development Manager Finance Manager Vancouver, BC V6Z 2K5 Meg Hughes, x 69464 Jo-Lynn Mervyn, x 69146

Medal Office Hours: 8:30 AM–4:00 PM, M–F Ethical Review Manager Research Institute Accountant Vivienne Bearder, x 63496 Freda Liang, x 63438 T: 604-806-8175 Clinical Research Contracts Mgr Research Accounts Bookkeeper F: 604-806-8568 Esther Wu, x 63199 Cindy Paddon, x 62843 W: www.providenceresearch.ca E: [email protected] Human Resources Coordinator Grants and Contracts Coordinator Raquel Park, x 62859 Gwen Sin, x 69102

www.providenceresearch.ca November 2009

RESEARCH EVENTS ALL ARE WELCOME TO ATTEND MESSAGE FROM YVONNE LEFEBVRE

November 3 & 17 VP RESEARCH & ACADEMIC AFFAIRS Toastmasters Club-everyone welcome Gourlay Conference Room, SPH, 12-1 PM I would like to extend sincere congratulations to Jim Hogg who Contact: [email protected] was inducted into the Canadian Medical Hall of Fame on October 16, 2009. Jim was recruited to UBC and St. Paul’s Hospital November 10 in 1977 from McGill University, and, as we all know, went on to The Practice of Peer Review build the world-renowned James Hogg iCAPTURE Centre for Last workshop of the 3-part manuscript Cardiovascular and Pulmonary Research in 2003. Some notable writing series examples of his many awards include being named an Officer of Gourlay Conference Rm, SPH, 9:30–11:30AM the Order of Canada, being elected to the Royal Society of Canada November 17 and having received the American Society for Investigative Ethics in Research Pathology Chugai Award. Jim joins 76 other Hall of Fame laureates A workshop for all researchers/research staff who have previously been inducted for pushing the boundaries of knowledge to improve Chan Centre for Family Health Education, human health. This year’s inductees were selected by an independent committee of CFRI, 950 West 28th Avenue, 9:00–11:30 AM prominent leaders from Canada’s medical community. November 18 With the many funding challenges that the Lower Mainland heath care and research Getting Your First Operating Grant communities have been tackling this fall, on September 29, 2009, the Michael Smith Funded! Foundation for Health Research received some encouraging news in a letter from the A workshop for post-doctoral fellows and Minister of Health Services, Honourable Kevin Falcon, confirming an additional $15 million junior faculty funding. Minister Falcon’s letter said that the additional $15 million would be provided Fac. of Medicine Post-Doctoral PD Series “prior to April 15, 2010” and emphasized that the Foundation should not anticipate New Lecture Theatre, SPH, 8:30–12:00 PM receiving additional funding from the Province of B.C. for the next two fiscal years November 18 (2009/10 and 2010/11). Dr. John Challis, MSFHR President and CEO, has said this will allow Business as Usual or Paradigm Shift in the the Foundation to make some key decisions around future directions for their programs Treatment of Complex Concurrent and initiatives. Disorders – The Burnaby Treatment Centre for Mental Health and Addiction Lastly, I’d like to extend additional congratulations to the PHCRI Trainees who received After One year of Experience MSFHR Research Trainee Program Awards on October 9, 2009. The awards support highly Dr. Michael Krausz qualified Master's, PhD and Post Doctoral trainees to prepare for careers as independent CHEOS Work in Progress Seminar health researchers. The recipients are listed on the second page of the Bulletin. Hurlburt Auditorium, SPH, 12-1 PM November 23 PHCRI RESEARCHER PROFILE Does Science have a Soul? Research for Children in a Complex World Janet McElhaney, MD, FRCPC, FACP Professor Fiona Stanley Professor of Medicine at the University of British Columbia The Alan Bernstein Distinguished Lecture (UBC), the Allan M. McGavin Chair in Geriatrics Research, Series PHC Physician Program Director for Elder Care Acute Services, New Lecture Theatre, SPH, 8:50–10:00 AM and Division Head of Geriatric Medicine for UBC, Providence Health Care and Vancouver General Hospital.

RESEARCH ETHICS BOARD Research Interests November DATES For Full Board Review Dr. McElhaney’s research focus is on the aging immune system, how this impacts on risk for influenza and protection against Next REB Meeting influenza through vaccination. Her research is supported by the Canadian Institutes of Friday, November 27 Health Research, the Michael Smith Foundation for Health Research, and the National Submission Deadline* Institutes of Health. She is an adviser to the European Scientific Working Group on Friday, November 6, 4:00 PM Influenza and on the advisory board of the Influenza Vaccine Project, a PATH initiative *Submissions must be approved by the Department Head and entered in RISe by this time. It is recommended that applications be supported by the Bill and Melinda Gates Foundation. sent to the Department Head at least 3 days in advance of the submission deadline. UPCOMING GRANT & RESEARCH EVENTS & WORKSHOPS AWARD DEADLINES COMING SOON! NOVEMBER 4: NOVEMBER 27: Vancouver Island Clinical Research Clinical Research On-Line Survey BC Centre for Excellence in NOVEMBER 14 Education Symposium In an effort to assist PHC clinical HIV/AIDS Forefront Lecture B.C. Lung Association – National Grant The 4th Vancouver Island Clinical Research researchers and to enhance the capacity Responding to the increase in Review Process Education Symposium will take place on for clinical research at PHC, the CHEOS crack cocaine use in Vancouver November 27, 2009. This is the first Clinical Trials Support Unit will be NOVEMBER 16 Speakers: Evan Wood, MD, PhD Canadian SoCRA/ACRP co-sponsored issuing a short, on-line survey. Its Kora DeBeck, MPP event. Members from either organization

purpose will be to gain understanding of Location: Hurlburt Auditorium will receive CE hours toward re-certification. UBC School of Nursing Internal the current PHC clinical research infra- At Noon; Light lunch and refreshments A block of rooms has been reserved at the Research Grants structure. The survey will be e-mailed to For information, contact Peter Vann at Magnolia Hotel & Spa in downtown everyone who is currently involved with [email protected] or 604.806.8549. Victoria at a room rate, including breakfast, NOVEMBER 16 clinical research including clinicians, of $109 (plus taxes) for the evening of clinical research coordinators and clinical Nov. 26. If there is availability, stays can be extended at this rate through the weekend. Canadian Diabetes 2010 Personnel research service providers (i.e., lab, To book your reservation, please contact : pharmacy and research ethics board). Awards Competition Vanessa Lowther, Sales Coordinator Erin Cherban, Manager, Clinical Trial The Magnolia Hotel & Spa, 623 Courtney St, NOVEMBER 16 Support Unit, will use the results from Victoria, TEL: 250.381.0997 (Ext 2004) the survey to formulate a plan to ensure Email: [email protected] Association of Faculties of Medicine of that the PHC clinical research group Web: http://www.magnoliahotel.com/ Canada Awards receives assistance they need to conduct For information on the conference, e-mail:: high quality clinical research. For info: [email protected] NOVEMBER 16 [email protected]

Canada/U.S. Fulbright Scholar Award ANNOUNCEMENTS AND ACHIEVEMENTS

NOVEMBER 26 Providence Health Care Responds to the MSFHR Research Trainee Program Awards Needs of Staff, Physicians and Patients Congratulations to the Master's, PhD and Post Doctoral Canadian Society for Clinical A new weekly communication tool will trainees who received a Michael Smith Foundation for Investigation Distinguished Scientist provide up-to-date news on H1N1 and how it Health Research 2009 Research Trainee Award. Our Lecture Award and Joe Doupe Young affects our workplace apologies to anyone we may have missed. Investigator Award Providence Health Care's Infection Prevention and • Bohdan Nosyk (Dr. Aslam Anis), Centre for Health Control (IPAC) and Workplace Wellness and Safety Evaluation and Outcome Sciences NOVEMBER 30 (WWS) teams have created a weekly communication designed to provide staff and physicians with • Tillie-Louise Hackett (Dr. Darryl Knight), iCAPTURE Centre Canadian Medical Association Awards Information they need to continue to meet the increased demand for care due to H1N1. The new • Margo Pearce (Dr. Patricia Spittal), CHEOS DECEMBER 1* bulletin, H1N1 Weekly, is a brief, easy-to-understand • Will Small (Dr. Thomas Kerr), B.C. Centre for document that can be read quickly and Is designed Excellence in HIV/AIDS for discussion at weekly program/department Canadian Diabetes 2010 Operating • Danya Fast (Dr. Thomas Kerr), B.C. Centre for Grant Competition meetings or at daily rounds. More detailed Excellence in HIV/AIDS information pertaining to PHC's management of *Registration deadline: Nov 2 H1N1 is available online at the Workplace Wellness and Safety and Infection Prevention and Control PHC DECEMBER 1 intranet sites . A copy of the latest H1N1 Weekly is

attached and will be distributed to our research Royal Society of Canada – community in the weekly PHCRI E-Alert. Flavelle Medal and McLaughlin Medal

DECEMBER 15 PHC RESEARCH INSTITUTE

Peter Gruber Foundation International VP Research & Academic Affairs Human Resources Manager Yvonne Lefebvre, PhD, x 68903 Kelly Ceron, x 68570 PHC RESEARCH INSTITUTE Awards Office of Research Services VP Executive Assistant/Coordinator, Human Resources Coordinator Communications & Events Raquel Park, x 62859 JANUARY 15 Gail Dibernardo x 69608 1190 Hornby Street, 11th Floor Finance Manager Vancouver, BC V6Z 2K5 Ethical Review Manager Jo-Lynn Mervyn, x 69146 Vivienne Bearder, x 63496 CIHR: 2009/2010 Michael Smith Prize in Research Institute Accountant Office Hours: 8:30 AM–4:00 PM, M–F Health Research Pre and Post Review Manager Freda Liang, x 63438 Nesa Kruse, x 68567 T: 604-806-8175 Research Accounts Bookkeeper F: 604-806-8568 Clinical Research Contracts Mgr Cindy Paddon, x 62843 Kidney Research Scientist Core W: www.providenceresearch.ca Esther Wu, x 63199 Education and National Training Research Finance Administrator E: [email protected] Program 2010 Competitions Grants and Contracts Coordinator Tracy Yang , x 66053 Gwen Sin, x 69102

www.providenceresearch.ca December 2009

RESEARCH EVENTS MESSAGE FROM YVONNE LEFEBVRE ALL ARE WELCOME TO ATTEND VP RESEARCH & ACADEMIC AFFAIRS On Friday, November 20th, I co-chaired a joint meeting of the December 2 Research Committee of the Association of Canadian Cognitive Factors and Willingness to Academic Healthcare Organizations (ACAHO) with the Participate in an HIV Vaccine Trial in Injection Drug Users Research Committee of the Association of Faculties of Shayesta Dhalla, MD, MHSc and (AFMC). These twice yearly meetings are usually productive Gary Poole, PhD and interesting because they bring together the individuals CHEOS Work in Progress Seminar who are responsible for most of the health research in Hurlburt Auditorium, SPH, 12:00-1:00 PM Canada. Two sessions were of particular interest. Alain December 4 Beaudet, President of CIHR, re-emphasized CIHR’s intention Propofol for Cardioprotection – the UBC to make ‘patient-oriented’ research a top priority in its new strategic plan. For Experience PHCRI, in a health care setting, more funding for clinical research and health Dr. David M. Ansley iCAPTURE Seminar Series services research will be welcome. The second session that especially caught my Gourlay Conf Room, SPH, 11:30-12:30 PM attention was the presentation by Jak Van Beek, Canadian Foundation for December 1 & 15 Innovation (CFI). As we have known for some time, CFI has an allocation of $600 Toastmasters Club-everyone welcome million to spend. We have also known that the call for proposals for at least some Gourlay Conference Room, SPH, 12-1 PM of this funding had to be made by the end of 2010. We also had believed that Contact: [email protected] some of this allocation would go towards the New Initiatives Fund (NIH) and December 11 Leading Edge Fund (LEF) competitions which were expected to be called by the Inflammatory Mechanisms in the end of 2009 or beginning of 2010. Current plans, although not finalized, are quite Development of Abdominal Aortic different. As it stands, there will be no new NIH or LEF competitions until Aneurysms 2011/2012. Of the $600 million which CFI currently holds, and which will be spent Dr. Alan Daugherty iCAPTURE Seminar Series before 2011/12, $140 million will go to the Infrastructure Operating Fund. There Gourlay Conf Room, SPH, 11:30-12:30 PM are several programs proposed for the remainder of the $600 million. Among December 16 these is a Platform category, a possible source of funding for a Clinical Trials Incidence and Outcomes of Diabetes Platform, which PHCRI with UBC and other partners have been designing for the Mellitus Among South Asian, Chinese and last year or so. Stay tuned! White Patients in BC and Alberta Nadia Khan PHCRI RESEARCHER PROFILE CHEOS Work in Progress Seminar Hurlburt Auditorium, SPH, 12:00-1:00 PM Douglas Cave, MSW, RSW, PhD, RPsych Psychologist at Centre for Practitioner Renewal RESEARCH ETHICS BOARD Providence Health Care November DATES Assistant Professor, Department of Community and Family Medicine, Department of Medicine, UBC For Full Board Review

Next REB Meeting Research Interests Friday, December 11 • Sustaining healthcare providers in the workplace Submission Deadline* • Communication among healthcare workers Friday, November 20, 4:00 PM

*Submissions must be approved by the Department Head and • Transition from military service to civilian life entered in RISe by this time. It is recommended that applications be sent to the Department Head at least 3 days in advance of the • Reciprocal relationship-based model of care submission deadline. • Clinical psychopharmacology

NEWS AROUND PROVIDENCE HEALTH CARE UPCOMING GRANT & AWARD DEADLINES December 1 – World AIDS Day determinants which help HIV flourish, these incidents, the patient information was continue on. not required by most of the individuals with st Each year on December 1 , the world whom it was shared, and for those who did observes World AIDS Day (WAD). It is a SPECIAL SEMINAR “The need to know who the patients were, DECEMBER 4 time to reflect on those who have passed Abdominal Circulatory Pump: another method of communication could away and those who have no access to have been used. In view of these incidents, A New Resource for Fogarty International Clinical HIV care. However it’s also a time to an information sheet outlining some of the acknowledge the excellent care we are Cardiopulmonary Research Scholars Support Center risks associated with using e-mail was able to provide in Canada, how HIV care Resuscitation?” created and is attached to this bulletin. and knowledge continue to grow year by Dr. Peter T. Macklem Please share it with co-workers and research DECEMBER 15 year, and how we all play a role in Professor Emeritus staff. For further information, contact PHC’s helping to reduce onward transmission Dept of Medicine, McGill University Leader of Information Access and Privacy, Peter Gruber Foundation via our patients. World AIDS Day aims to Friday, December 11, 2009 Janet Scott at tel. 604-806-8336, or via e- International Awards strengthen concerted global efforts to 2:00 – 3:00 pm mail to [email protected]. address the challenge of the AIDS Gourlay Conference Room pandemic which continues to spread 1st Floor, iCAPTURE Centre, JANUARY 15, 2010 death and disease throughout the world. St. Paul’s Hospital Providence Health Care remains Contact Shemim Manji at 604-806-9033 CIHR: 2009/2010 Michael Smith Prize extremely proud of the unique response for information in Health Research by our organization and our founding Sisters to the HIV and AIDS crisis. On this Privacy and E-mail Messages day, PHC and the BC Centre for CIHR: Age+ Prize There have been two recent incidents Excellence in HIV/AIDS invite you to where patient personal information was remember that the fight against Kidney Research Scientist Core communicated via e-mail. In both of HIV/AIDS, its stigma and the social Education and National Training Program 2010 Competitions ANNOUNCEMENTS AND ACHIEVEMENTS James Kreppner Fellowship in Blood Congratulations! CASTVB Scientific 2010 Olympic Winter Games PHC System Studies Excellence Award (2009) Preparedness – Frequently Asked Questions

JANUARY 29 Congratulations to Dr. Bruce McManus who is the Based on questions from staff, physicians and nd 2 recipient of the CASTVB Scientific Excellence researchers received through the PHC staff forums, Vanderbilt Prize in Biomedical Science Award (2009). The CSATVB Scientific Excellence multiple presentations to targeted groups and by Award is sponsored by the Canadian Society for email/phone, the attached frequently asked FEBRUARY 1 Atherosclerosis, Thrombosis and Vascular Biology. questions document was created. This Q&A An Award of $2000 is given to an active researcher document will be updated and circulated regularly CIHR: Chair, GlaxoSmithKline for consistent outstanding and innovative research and will be posted on the 2010Ready intranet site Partnered (2009-2010) in the areas of atherosclerosis, thrombosis and/or under the Providence Health Care Olympic vascular biology. Read more at CSATVB Scientific Planning section. Updates will be sent to PHCRI CIHR: Operating Grant 2009-2010 Excellence Award. research community via weekly E-Alerts. New BC Nursing Health Services Research The Q&A will answer questions you may have been CIHR: Rx&D Collaborative Research Network Launched wondering about, such as “What health services are (2009-2010) VCH and PHC providing to the Games?” or “What The NHSRN is one of several funding strategies that will be implemented through the BC Nursing does it mean that St. Paul’s Hospital has been 2010 UBC Killam Teaching Prizes: see designated the official Spectator Hospital?” There is attached application Research Initiative (BCNRI); a research and capacity-building initiative supported by the also important information on access to PHC sites

Michael Smith Foundation for Health Research. during the Olympics, so be sure to keep this file FEBRUARY 2 http://www.msfhr.org/news/news_blog/2009/11/nursing_network handy for easy reference.

CIHR: Randomized Controlled TTrials: Mentoring (2009-2010) PHC RESEARCH INSTITUTE

FEBRUARY 5 VP Research & Academic Affairs Human Resources Manager Yvonne Lefebvre, PhD, x 68903 Kelly Ceron, x 68570 PHC RESEARCH INSTITUTE CUFA BC : Distinguished Academics Office of Research Services VP Executive Assistant/Coordinator, Human Resources Coordinator Awards Communications & Events Raquel Park, x 62859 th Gail Dibernardo x 69608 1190 Hornby Street, 11 Floor Finance Manager Vancouver, BC V6Z 2K5 FEBRUARY 28 Ethical Review Manager Jo-Lynn Mervyn, x 69146 Vivienne Bearder, x 63496 Research Institute Accountant Office Hours: 8:30 AM–4:00 PM, M–F Canadian Association for Nursing Pre and Post Review Manager Freda Liang, x 63438 Nesa Kruse, x 68567 T: 604-806-8175 Research Awards Research Accounts Bookkeeper F: 604-806-8568 Clinical Research Contracts Mgr Cindy Paddon, x 62843 W: www.providenceresearch.ca Esther Wu, x 63199 Research Finance Administrator E: [email protected] Grants and Contracts Coordinator Tracy Yang , x 66053 Gwen Sin, x 69102