Chronic Otitis Media: Histopathological Changes a Post Mortem Study on Temporal Bones
European Review for Medical and Pharmacological Sciences 1999; 3: 175-178 Chronic otitis media: histopathological changes A post mortem study on temporal bones F. SALVINELLI, M. TRIVELLI, F. GRECO, F.H. LINTHICUM JR* Institute of Otolaryngology, “Campus Bio-Medico” University - Rome (Italy) *Department of Histopathology, “House Ear Institute” - Los Angeles, CA (USA) Abstract. – The temporal bones of 4 Materials and Methods deceased individuals, with concomitant chronic otitis media are studied. The various histopathological changes in the middle ear We have studied the histopathological cleft are examined: suppuration, polyps, changes in temporal bones of 4 deceased in- granulation tissue. The possibilities of spon- dividuals, with concomitant chronic OM. taneous healing of a perforated TM and the These patients were donors and agreed indications of surgical treatment are dis- during their life to donate post mortem their cussed. temporal bones to the House Ear Institute as Key Words: a contribution to a better knowledge of tem- Temporal bone, Middle ear, Infection, Chronic in- poral bone diseases. flammation, Metaplasia, Complications. We have removed the temporal bones in our usual way9. Introduction Results Otitis media (OM) is an infection localized Clinical features in the middle ear: mastoid, middle ear cavity, The inflammation, while often indolent, eustachian tube. The classification of OM in- may at times give rise to serious complica- cludes: tions and even cause death. The hearing loss that is a constant concomitant also con- tributes to the immense socio-economic problem. Chronic OM sometimes, but not al- • OM with effusion1-3, without perforation ways, follows an attack of the acute disease. of the tympanic membrane (TM)4-6, due The major feature is discharge from the mid- to an increase of fluid in the middle ear dle ear.
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