Featured biochemicals for neuroscience

Ab ID Product Name Research Area Description QX-314 chloride 120118 Neuroscience, Cancer Na+ channel blocker (N-Ethyllidocaine chloride) Free radical scavenger with 120645 Edaravone (MCI-186) Neuroscience, Cancer neuroprotective effects Blocker of TRP cation channels. 120280 SKF 96365 Neuroscience, Cancer Inhibits capacitative Ca2+ entry. 120658 Calmidazolium chloride Neuroscience, Cancer Calmodulin inhibitor Antioxidant polyphenol with a 120726 Resveratrol Neuroscience, Cancer multitude of biological activities 120158 E-4031 dihydrochloride Neuroscience, Cancer HERG K+ channel blocker Store-operated Ca2+ entry blocker. YM-58483 (CRAC Channel 144413 Neuroscience, Cancer Potent, selective CRAC channel Inhibitor, BTP2) inhibitor. Potent, selective KCNQ channel 120089 XE-991 dihydrochloride Neuroscience, Cancer blocker; blocks M current Potent and selective reversible 145868 HC 067047 Neuroscience, Cancer TRPV4 antagonist Isoprenaline hydrochloride Non-selective β adrenoceptor 120710 Neuroscience, Cancer (Isoproterenol) agonist 120014 SNAP Neuroscience, Cancer NO donor 120122 4-Aminopyridine (4-AP) Neuroscience, Cancer K+ channel blocker 120980 KN-93 (water soluble) Neuroscience, Cancer Potent, specific CaMK II inhibitor Pyridoxal isonicotinoyl Cell-permeable non-toxic hydrazone 145871 Neuroscience, Cancer hydrazone (PIH) iron chelator 120366 (plusminus)-BAYK8644 Neuroscience, Cancer Potent L-type Ca2+ channel activator Activator of Ca2+-activated K+ 120258 1-EBIO Neuroscience, Cancer channels and CFTR channels 120219 Gabapentin Neuroscience, Cancer α2δ Ligand 143564 ML297 (VU0456810) Neuroscience, Cancer Potent, selective GIRK activator 120012 CGP 37157 Neuroscience, Cancer Na+-Ca2+ exchange inhibitor (N-Acetyl-L- ROS inhibitor. L-cysteine prodrug. 143032 Neuroscience, Cancer cysteine) Mucolytic agent. 145870 Valspodar (PSC-833) Neuroscience, Cancer Selective P-glycoprotein inhibitor

120337 CGP 55845 hydrochloride Neuroscience Potent, selective GABAB antagonist (+)-MK 801 maleate 120027 Neuroscience Non-competitive NMDA antagonist (Dizocilpine) 120007 (S)-3,5-DHPG Neuroscience Selective group I mGlu agonist 120041 Neuroscience Excitotoxic agonist AMPA / kainate antagonist; water 120169 DNQX disodium salt Neuroscience soluble 120049 L-Glutamate Neuroscience Excitatory neurotransmitter 120017 CNQX Neuroscience AMPA / kainate antagonist

120008 MPEP hydrochloride Neuroscience Potent, selective mGlu5 antagonist

120107 (+)-Bicuculline Neuroscience GABAA antagonist Novel pH responsive FFN. Measures 120866 FFN102 (Mini 102) Neuroscience localization and activity of dopaminergic presynaptic terminals. 120002 L-AP4 Neuroscience Selective group III mGlu agonist

120384 UDP-glucose Neuroscience Highly potent P2Y14 agonist CB receptor antagonist / inverse 120088 AM251 Neuroscience 1 agonist Novel and highly fluorescent VMAT2 144554 FFN206 Neuroscience substrate 120763 Donepezil hydrochloride Neuroscience Acetylcholinesterase inhibitor

120414 MRS 2179 Neuroscience Potent, selective P2Y1 antagonist 120290 Ro 25-6981 maleate salt Neuroscience NR2B antagonist GluN2B (formerly NR2B)-preferring 120111 Ifenprodil hemitartrate Neuroscience NMDA antagonist 120147 Herkinorin Neuroscience Non-internalising μ opioid agonist Potent, selective, silent 5-HT 120550 WAY-100635 maleate Neuroscience 1A receptor antagonist 120018 DNQX Neuroscience AMPA / kainate antagonist

120167 CGP 35348 Neuroscience GABAB antagonist, brain penetrant 120077 Fluoxetine hydrochloride Neuroscience 5-HT reuptake inhibitor

120011 AMN082 dihydrochloride Neuroscience mGlu7 agonist

120109 (-)-Bicuculline methobromide Neuroscience GABAA antagonist Selective GluR2 lacking AMPA 141507 IEM-1460 Neuroscience receptor blocker. Open channel blocker. Potent and selective M positive 141510 VU0152100 Neuroscience 4 allosteric modulator 120558 PNU 282987 Neuroscience Selective α7 nAChR agonist 120009 PPADS Neuroscience P2 purinergic receptor antagonist Selective, non-competitive mGlu 120060 CPCCOEt Neuroscience 1 antagonist Serotonin hydrochloride Endogenous neurotransmitter, 5-HT 120528 Neuroscience (5-HT/5-Hydroxytryptamine) receptor agonist Highly selective β adrenoceptor 120808 ICI 118551 hydrochloride Neuroscience 2 antagonist 2-Chloro-N6-

120434 cyclopentyladenosine Neuroscience Highly potent, selective A1 agonist (CCPA) Mecamylamine Non-competitive antagonist of 120459 Neuroscience hydrochloride nicotinic receptors Potent, selective group II antagonist. 120199 LY 341495 Neuroscience Group III antagonist at higher concentrations. First novel fluorescent false neurotransmitter. Enables optical 120331 FFN511 Neuroscience imaging of presynaptic terminal activity. 120133 Citalopram Neuroscience 5-HT reuptake inhibitor

120396 DPCPX Neuroscience Potent A1 antagonist gamma-DGG (gamma-D- Ionotropic glutamate antagonist. 120307 Neuroscience Glutamylglycine) Low affinity AMPA antagonist. NMDA receptor glycine site 120023 5,7-Dichlorokynurenic acid Neuroscience antagonist GluK1 and GluK3 selective 120168 UBP310 Neuroscience antagonist Positive GABA receptor allosteric 120492 CGP 7930 Neuroscience B modulator 120530 Methysergide maleate Neuroscience 5-HT receptor antagonist Positive allosteric modulator for the 120559 PNU 120596 Neuroscience α7 nicotinic acetylcholine receptor Group I /II metabotropic glutamate 120033 (R,S)-MCPG Neuroscience antagonist Potent, selective β adrenoceptor 141135 SR 59230A hydrochloride Neuroscience 3 antagonist Peripheral D -like receptor 120566 Domperidone Neuroscience 2 antagonist

120593 LP-44 Neuroscience Highly potent, selective 5-HT7 agonist Potent competitive NMDA 120232 (R)-CPPene (SDZ EAA 494) Neuroscience antagonist RuBi-GABA-PMe3 (water Novel modified version of RuBi- 141189 Neuroscience soluble) GABA. Inhibits neural activity.