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UC San Diego UC San Diego Electronic Theses and Dissertations Title Multimodal evidence Permalink https://escholarship.org/uc/item/2x54p2rw Author Stegenga, Jacob Publication Date 2011 Peer reviewed|Thesis/dissertation eScholarship.org Powered by the California Digital Library University of California UNIVERSITY OF CALIFORNIA, SAN DIEGO Multimodal Evidence A dissertation submitted in partial satisfaction of the requirements for the degree Doctor of Philosophy in Philosophy by Jacob Stegenga Committee in charge: Professor Nancy Cartwright, Chair Professor William Bechtel Professor Craig Callender Professor Naomi Oreskes Professor Robert Westman 2011 © Jacob Stegenga, 2011 All rights reserved. The Dissertation of Jacob Stegenga is approved, and it is acceptable in quality and form for publication on microfilm and electronically: Chair University of California, San Diego 2011 iii For Skye, who teaches that there is much about which to argue; For my Mother, whose arguments are sparing, and kind; For Bob, who argues well; For Alexa, who knows that one need not always argue. iv It is the profession of philosophers to question platitudes. A dangerous profession, since philosophers are more easily discredited than platitudes. David Lewis v TABLE OF CONTENTS Signature Page……………………………………………………………… iii Dedication………………………………………………………………….. iv Epigraph……………………………………………………………………. v Table of Contents…………………………………………………………... vi List of Tables………………………………………………………………. vii List of Terminology………………………………………………………... viii List of Abbreviations and Symbols………………………………………… xii Acknowledgements………………………………………………………… xiv Vita…………………………………………………………………………. xviii Abstract…………………………………………………………………….. xix Chapter 1: Introduction…………………………………………………….. 1 Chapter 2: Varieties of Evidential Experience……………………………... 14 Chapter 3: Underdetermination of Evidence by Theory…………………… 49 Chapter 4: Independent Evidence………………………………………….. 75 Chapter 5: Robustness, Discordance, and Relevance……………………… 102 Chapter 6: Amalgamating Multimodal Evidence………………………….. 124 Chapter 7: Is Meta-Analysis the Platinum Standard of Evidence?………… 145 Chapter 8: An Impossibility Theorem for Amalgamating Evidence………. 176 References………………………………………………………………….. 214 vi LIST OF TABLES Table 1. Features of Evidence……………………………………………… 33 Table 2. Likelihoods of Evidence in La Jolla Murder Mystery……………. 90 Table 3. Binary Outcomes in an Experiment and Control Group………….. 167 Table 4. Analogy Between Amalgamating Preferences and Amalgamating Evidence…………………………………………………… 182 Table 5. Profiles Constructed in Proof of Impossibility Theorem for Amalgamating Evidence…………………………………………………… 212 vii LIST OF TERMINOLOGY In this dissertation my use of some words departs slightly from standard philosophical or scientific usage, and for some concepts I have had to invent entirely new words or phrases. The following glossary provides informal definitions of such terms; for terms that have a corresponding formal definition I indicate its location in the dissertation. Technical terms used in standard ways (such as ‘meta-analysis’) are defined in the body of the dissertation. Amalgamation The combination of multimodal evidence. Amalgamation Method A method to amalgamate multimodal evidence into a measure of overall support for a hypothesis. Amalgamation Function A type of amalgamation method, the inputs and output of which are limited to ordinal rankings of hypotheses (formal definition on page 186- 187). Concordance Consistency or agreement of evidence from multiple modes. viii Conditional Probabilistic Independence Probabilistic independence between multiple modes of evidence, conditional on a hypothesis (formal definition on page 96). Confirmation Ordering A confirmation relation, denoted by ≽i , where i is a mode (the confirmation ordering relation is indexed to the mode of evidence), such that H1 ≽i H2 means “evidence from mode i confirmation orders H1 equally to or above H2” (formal definition on page 183-184). Constraint A desideratum of amalgamation methods which stipulates that AMs should constrain intersubjective assessment of hypotheses. Dictatorship A mode of evidence which always trumps other modes in an amalgamation function. One of the desiderata for an amalgamation function is ‘non-dictatorship’, which stipulates that no mode should be a dictator (formal definition on page 208). ix Discordance Inconsistency or disagreement of evidence from multiple modes. Dyssynergistic Evidence Multimodal evidence which confirms the negation of a hypothesis which is confirmed by evidence from the individual modes constituting the multimodal evidence (formal definition on page 89). Independence of Irrelevant Alternatives A desideratum for amalgamation functions which stipulates that a ranking of two hypotheses relative to each other by an amalgamation function should depend only on how the individual modes rank these two hypotheses relative to each other, and not on how the modes rank them relative to other hypotheses (formal definition on page 207-208). Mode A method of producing evidence or a particular way of learning about the world: a technique, apparatus, or experiment. Modes are types of which there can be a plurality of tokens. A full account of modes requires a criterion of individuation of modes, which is the subject of Chapter 4. x Multimodal Evidence The set of evidence produced by multiple independent modes relevant to a given hypothesis (formal notation on page 183). Ontic Independence The form of independence between multiple modes of evidence based on different materials constituting the modes or different assumptions or theories required by the modes. Robustness The state in which a hypothesis is supported by concordant multimodal evidence. Unanimity A desideratum for amalgamation functions which stipulates that if all modes confirm hypothesis H1 over H2, then the amalgamation function must do the same (formal definition on page 207). Unrestricted Domain A desideratum for amalgamation functions which stipulates that the amalgamation function can accept as input all possible confirmation orderings. xi LIST OF ABBREVIATIONS AND SYMBOLS AMM1944 Avery, McLeod, and McCarty (1944) AEC Atomic Energy Commission AF Amalgamation Function AM Amalgamation Method B Believability BT Bayes’ Theorem C Concordance CPI Conditional Probabilistic Independence D Non-Dictatorship DE Dyssynergistic Evidence DNA Deoxyribonucleic Acid e Evidence H Hypothesis I Independence of Irrelevant Alternatives JC Jeffrey Conditionalization NAS National Academy of Sciences NRS Non-randomized Study OI Ontic Independence P Patterns p(x) Probability of x xii p(x|y) Probability of x conditional on y Q Quality R Relevance RCT Randomized Controlled Trial RD Risk Difference RR Risk Ratio SC Strict Conditionalization T Transparency TS Transforming Substance U Unanimity UET Underdetermination of Evidence by Theory UV Ultraviolet xiii ACKNOWLEDGEMENTS The time and critical attention which Nancy Cartwright has dedicated to this dissertation is incredible; she has had an enormous influence on the material presented here. Nancy’s influence goes far beyond her copious written feedback on multiple drafts of these chapters. Our rambles through the English countryside and hikes through California deserts were ideal ways to work through material in the following pages. Her own work is my exemplar, as is her work ethic – I am grateful for Nancy’s supervision. Graduate students are often asked who is on their supervisory committee. My response has always felt like a boast. Bill Bechtel’s leadership of the Philosophy of Biology Research Group allowed discussions which helped to develop nascent ideas into chapters. Craig Callender encouraged me to pursue the eccentric topics that constitute this dissertation, criticized my work when needed, and provided guidance on broader matters of graduate study. I am grateful to Bill and Craig for being proxy advisors. During early discussions, and in her reading of my prospectus, Naomi Oreskes posed questions which have occupied me for two years. Bob Westman has provided thoughtful guidance since my first weeks at UCSD when I took his seminar in history and philosophy of science. Moreover, Bob has facilitated the development of my dissertation, and my ability to share it in a dozen cities, via his directorship of the Science Studies Program. I know too well that this dissertation is not what Bill, Craig, Naomi, or Bob had hoped for; I wish that it could suffice as its own apology. xiv Several other faculty members in the philosophy department provided feedback on aspects of my dissertation, including Don Rutherford, Sam Rickless, Christian Wüthrich, Rick Grush, David Brink, and Clinton Tolley. My fellow graduate students at UCSD have been heavily involved with this dissertation. Tarun Menon has encouraged and challenged me from the start, and has read most of this dissertation and spent many hours discussing it with me. Tarun is also a co-author of Chapter 4. I am fortunate to have Tarun as a colleague and friend. Eric Martin’s paper on combining evidence was an early inspiration. Long bike rides through San Diego County with Charlie Kurth were a great way to discuss philosophy. Daniel Schwartz, Ioan Muntean, Cole Macke, Sindhuja Bhakthavatsalam, Nat Jacobs, Marta Halina, Matt Brown, and Joyce Havstad have read parts of this dissertation and provided critical feedback. My fellow students engaged this work when it was in early, painfully inchoate stages, and so their fortitude is admirable. Nancy occasionally