XXXI International Congress of the International Academy of Pathology and 28Th Congress of the European Society of Pathology

Total Page:16

File Type:pdf, Size:1020Kb

XXXI International Congress of the International Academy of Pathology and 28Th Congress of the European Society of Pathology © KölnTourismus GmbH_Dieter Jacobi XXXI International Congress of the International Academy of Pathology and 28th Congress of the European Society of Pathology Predictive Pathology, Guiding and Monitoring Therapy 25 – 29 September 2016 Congress-Centrum Ost Koelnmesse, Cologne, Germany www.iap2016.com www.esp-congress.org Final Programme jointly organised by e German Division of the IAP e European Society of Pathology e Host Organisation e Scientific Contacts German Division of the International Martina Schmidt Academy of Pathology, Inc. Managing Director of the German Division of Joseph-Schumpeter-Allee 33 the IAP 53227 Bonn, Germany Joseph-Schumpeter-Allee 33 www.iap-bonn.de 53227 Bonn, Germany Email: [email protected] European Society of Pathology Rue Bara 6 Raed Al Dieri 1070 Brussels, Belgium ESP Scientific Director www.esp-pathology.org Rue Bara 6 1070 Brussels, Belgium Email: [email protected] IAP / ESP 2016 · Cologne Table of Contents page page Welcome Address 4 One Day Symposium for Information Technology 77 Organisers and Committees 5 Wednesday, 28 September 2016 78 Conveners 7 One Day Workshop for Technicians (TEC) 79 Keynote Speakers 9 Thursday, 29 September 2016 80 Bursaries 13 Poster Sessions 81 Monday, 26 September 2016 82 CME Accreditation 14 Tuesday, 27 September 2016 98 Wednesday, 28 September 2016 114 Venue Overview 15 Thursday, 29 September 2016 130 Programme Overview 16 E-Posters 147 Colour Legend 16 Sunday, 25 September 2016 17 Congress Information 181 Monday, 26 September 2016 18 Tuesday, 27 September 2016 20 Industry Symposia 187 Wednesday, 28 September 2016 22 Thursday, 29 September 2016 24 Acknowledgements 195 Scientific Programme 27 Exhibition Floor Plan 199 Sunday, 25 September 2016 28 Monday, 26 September 2016 28 List of Exhibitors 200 Tuesday, 27 September 2016 39 Wednesday, 28 September 2016 51 Social Events 205 Thursday, 29 September 2016 63 Tours 210 Two Day Symposium for Molecular Biologists 73 Index of Authors 215 Monday, 26 September 2016 74 Tuesday, 27 September 2016 75 e Congress and Exhibition Office e Congress Venue Congress-Centrum Ost Koelnmesse Deutz-Mülheimer Straße 51 CPO HANSER SERVICE GmbH 50679 Köln, Germany Paulsborner Str. 44 www.koelnkongress.de 14193 Berlin, Germany Phone: +49 – 30 – 300 669-0 Fax: +49 – 30 – 305 73 91 Email: [email protected] www.iap2016.com www.esp-congress.org 3 Welcome Address IAP / ESP 2016 · Cologne Dear Colleague, Welcome to the XXXI International Congress of the Interna- tional Academy of Pathology and 28th Congress of the Euro- pean Society of Pathology which is for the first time organised as a joint venture. Cologne is Germany's fourth-largest city, and is the largest city both in the German Federal State of North Rhine-West- phalia and within the Rhine-Ruhr Metropolitan Area, one of the major European metropolitan areas with more than ten million inhabitants. Cologne is located on both sides of the Dietmar Schmidt Rhine River. The city's famous Cologne Cathedral is the seat of the Catholic Archbishop of Cologne. The University of Cologne is one of Europe's oldest and largest universities. Cologne is a major cultural centre for the Rhineland; it is home to more than thirty museums and hundreds of galler- ies. Exhibitions range from local ancient Roman archeological sites to contemporary graphics and sculptures. On behalf of the German Division of the International Acad- emy of Pathology and the European Society of Pathology we are looking forward to an exciting and stimulating congress that will reflect recent developments in diagnostic and mo- lecular pathology. Pierre Bedossa The motto of the Congress – Predictive Pathology, Guiding and Monitoring Therapy – indicates the future role of patholo- gy as a strong partner for the different clinical specialties. The scientific programme includes science, translational research and clinical application to provide delegates with information on recent research findings, new technologies and up to date education. In addition to providing an interesting scientific and educa- tional programme the IAP / ESP 2016 meeting serves as a get-together for pathologists and scientists from all over the world in a friendly atmosphere. We look forward to seeing you and spending a great time in Cologne. Dietmar Schmidt & Pierre Bedossa Congress Presidents 2016 4 IAP / ESP 2016 · Cologne Organisers and Committees e GDIAP ning the division has developed a continuing The concept of an international academy of educational program that consists of an an- pathology originated in 1906 when Maude nual 3-day symposium in February or March, Abbott, M.D. from the McGill University in case-based whole day tutorials on most Montreal, Canada, Major James Carroll from weekends over the year, and satellite meet- Washington, D.C. and W. G. MacCallum, ings. In addition, joint meetings and courses M.D. from Baltimore, Maryland met at the have been organized with other divisions. Army Medical Museum in Washington, D.C., The other two organisations are the German and later in Baltimore, Maryland and formed Society of Pathology, founded in 1897, focus- an organizing committee to establish an In- ing on research and academic pathology and ternational Association of Medical Museums. the Professional Organisation of the German A letter of invitation was sent to the leading Pathologists dealing with political and eco- medical museums throughout the world re- nomic issues. questing them to join in forming an interna- tional association. This led to the formal or- German Division of the International ganisation of the International Association of Academy of Pathology, Inc. Medical Museums (IAMM). Joseph-Schumpeter-Allee 33 In 1955 the name of the IAMM was changed 53227 Bonn, Germany to the International Academy of Pathology Phone: +49 – 228-282404 (IAP). In 1969, new Constitution and Bylaws Fax: +49 – 228-284796 formalized both the Divisional and Interna- Email: [email protected] tional organisation of the International Acad- www.iap-bonn.de emy of Pathology. Divisions evolved in vari- ous countries throughout the world. Today, the IAP consists of 56 divisions of which the e ESP largest is the US-Canadian Division followed The European Society of Pathology (ESP) was by the German Division. established in 1963 in Brussels and is a lead- The German Division of the IAP was founded ing force in European pathology and, as such, in 1964 by an initiative of Prof. Herwig Ham- is pivotal to the future of the specialty in Eu- perl. The First Business Meeting with the rope and beyond. As a scientific society, the election of the first board was held during ESP has, as its primary aim, the promotion of the 49th Meeting of the German Society of high quality diagnostic practice, applied and Pathology in 1965, in the city of Saarbrücken. translational research and under- and post- On July 10, 1967, the first symposium of the graduate education in the field of human German Division was organised in the au- pathology. This is achieved through its con- ditorium of the Institute of Pathology of the gresses, its journal Virchows Archiv and vari- University of Bonn. The German IAP division ous other activities. The ESP interacts with na- has been a German speaking organisation tional pathology societies in Europe and has with members not only from Germany but developed links with other EU bodies in close also Austria and Switzerland and recently collaboration with UEMS (Union Européenne also from non-German speaking countries. des Médecins Spécialistes) and EAPCP (Eu- In Germany, it represents one of the three ropean Association of Pathol ogy Chairs and professional organisations for pathology. The Programme Directors). main focus of the professional activities of The European School of Pathology under the the German IAP division is practice-oriented auspices of the ESP and with the support of 19 and timely education and training for board Working Groups representing different fields certified pathologists and trainees. The head- of pathology is involved in the organisation of quarters of the German Division is located courses to meet the needs of young patholo- in Bonn providing ample space for teaching gists. The ESP also provides an infrastructure rooms and office. It harbours an auditorium for quality assurance projects in diagnostic with up-to-date audio-visual facilities and molecular pathology, such as the ESP QA microscopes for 63 people. Since its begin- KRAS project for testing of colorectal cancer. 5 Organisers and Committees IAP / ESP 2016 · Cologne Office of the ESP e IAP Council Executive Rue Bara 6, 1070 Brussels, Belgium President: Phone: +32 – 25208036 Eduardo Santini-Araujo, Argentina Email: [email protected] President Elect: www.esp-pathology.org George Kontogeorgos, Greece Past President: Samir Amr, Saudi Arabia e Scientific / Organising Committee Secretary: Dietmar Schmidt, Germany Ray McMahon, UK Pierre Bedossa, France Treasurer: Sigurd Lax, Austria Fred Silva, USA Han van Krieken, The Netherlands International Congresses Coord. & Asst. Fátima Carneiro, Portugal Treasurer: Reinhard Büttner, Germany Jim Crimmins, USA Executive Assistant: Charles Ramey, Canada e Executive Council of the ESP President: Pierre Bedossa, France e Executive Council of the GDIAP President-elect: President: Dina Tiniakos, Greece Sigurd Lax, Austria Secretary: Past President: Ilmo Leivo, Finland Thomas Rüdiger, Germany Treasurer: President-elect: Marco Santucci, Italy Eva Wardelmann, Germany Past President: Secretary / Treasurer: Han van Krieken, The Netherlands Klaus-Michael Müller, Germany Members: Members: Peter Schirmacher, Germany Uta Drebber, Germany Metka Volavšek, Slovenia Arndt Hartmann, Germany Tibor Tot, Sweden Wolfram Klapper, Germany Cord Langner, Austria Administrative Director: Xavier Mathias-Guiu, Spain Martina Schmidt, Germany Gordan M. Vujanic, UK Aleš Ryška, Czech Republic Holger Moch, Switzerland Chair of the Advisory Board: Fátima Carneiro, Portugal ESP Scientific Director: Raed Al Dieri, The Netherlands 6 IAP / ESP 2016 · Cologne Conveners Chair of the ESP Working Groups: Han van Krieken, The Netherlands 1. Breast Pathology 9. Head and Neck Pathology ESP convener: A.
Recommended publications
  • Malignant Peritoneal Mesothelioma: Clinical Aspects, and Therapeutic Perspectives
    REVIEW ARTICLE Annals of Gastroenterology (2018) 31, 1-11 Malignant peritoneal mesothelioma: clinical aspects, and therapeutic perspectives Stergios Boussiosa, Michele Moschettab, Afroditi Karathanasia, Alexandros K. Tsiourisc, Foivos S. Kanellosc, Konstantina Tatsid, Konstantinos H. Katsanose, Dimitrios K. Christodouloue Medway NHS Foundation Trust, Kent, UK; Sarah Cannon Research Institute, London, UK; University of Ioannina, Greece; General Hospital G. Hatzikosta, Ioannina, Greece Abstract Malignant peritoneal mesothelioma (MPM) is a rare disease with a wide clinical spectrum. It arises from the peritoneal lining and commonly presents with diffuse, extensive spread throughout the abdomen and, more rarely, metastatic spread beyond the abdominal cavity. Computed tomography, magnetic resonance imaging and positron-emission tomography are important diagnostic tools used for the preoperative staging of MPM. The definitive diagnosis is based on histopathological analysis, mainly via immunohistochemistry. In this regard, paired- box gene 8 negativity represents a useful diagnostic biomarker for differentiating MPM from ovarian carcinoma. In addition, BRCA1-associated protein-1 (BAP1) loss is specific to MPM and allows it to be distinguished from both benign mesothelial lesions and ovarian serous tumors. Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) has become an increasingly important therapeutic approach, while systemic therapies are still being developed. Histology, Ki-67, completeness of cytoreduction,
    [Show full text]
  • Mesothelin's Role As a Biomarker and Therapeutic Target for Malignant
    cancers Review Hitting the Bull’s-Eye: Mesothelin’s Role as a Biomarker and Therapeutic Target for Malignant Pleural Mesothelioma Dannel Yeo 1,2,3 , Laura Castelletti 1,2,3 , Nico van Zandwijk 2,3,4 and John E. J. Rasko 1,2,3,5,* 1 Li Ka Shing Cell & Gene Therapy Program, The University of Sydney, Camperdown, NSW 2050, Australia; [email protected] (D.Y.); [email protected] (L.C.) 2 Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW 2050, Australia; [email protected] 3 Cell and Molecular Therapies, Royal Prince Alfred Hospital, Sydney Local Health District (SLHD), Camperdown, NSW 2050, Australia 4 Concord Repatriation General Hospital, Sydney Local Health District (SLHD), Concord, NSW 2139, Australia 5 Gene and Stem Cell Therapy Program, Centenary Institute, The University of Sydney, Camperdown, NSW 2050, Australia * Correspondence: [email protected]; Tel.: +61-295656160 Simple Summary: Mesothelioma is a deadly disease with a dismal prognosis. Since its discovery, mesothelin, a cell surface protein, has been a promising biomarker and therapeutic target due to its overexpression in mesothelioma and limited expression in normal cells. This review summarizes the clinical studies that have examined mesothelin as a biomarker and therapeutic target in mesothelioma and explores future perspectives in its role to improve patient management. Abstract: Malignant pleural mesothelioma (MPM) is an aggressive cancer with limited treatment options and poor prognosis. MPM originates from the mesothelial lining of the pleura. Mesothelin Citation: Yeo, D.; Castelletti, L.; van (MSLN) is a glycoprotein expressed at low levels in normal tissues and at high levels in MPM.
    [Show full text]
  • St James Infirmary Guide.Pdf
    The St. James Infirmary is an Occupational Safety & Health Clinic for Sex Workers founded by COYOTE--Call Off Your Old Tired Ethics, and is a joint project between Exotic Dancers Alliance and the STD (Sexually Transmitted Disease) Prevention and Control Services of the City and County of San Francisco Department of Public Health. Our mission is to provide non-judgmental and compassionate health care and social services for all Sex Workers while preventing occupational illnesses and injuries throughout the sex industry. We provide services for current, former, and transitioning Street and Survival Sex Workers, Escorts, Sensual Massage workers, Erotic Performers and Entertainers, Exotic Dancers, Peep Show workers, Bondage/ Dominatrix/Sado-Masochism (BDSM) workers, Adult Film actors, Nude Models, Internet Pornography workers, Phone Sex operators, and Sex Toy Store workers. HOW TO USE THIS GUIDE This resource guide was prepared by Sex Workers for Sex Workers, and is produced with funds received from The California Endowment, the Franklin Benevolent Corporation and the SFDPH AIDS office. The information throughout the following pages is meant to provide you with helpful tips so that you can make informed choices about your health and well-being. Organizations with a © have received In-Service trainings from St. James Infirmary staff and/or collaborated and/or networked with us to provide comprehensive services to Sex Workers. We welcome your comments and suggestions about any of the following information, and we hope to see you soon at the
    [Show full text]
  • UEMS 2020.11 Syllabus of the ETR in Rare Adult Cancers
    UNION EUROPÉENNE DES MÉDECINS SPÉCIALISTES EUROPEAN UNION OF MEDICAL SPECIALISTS Association internationale sans but lucratif International non-profit organisation RUE DE L’INDUSTRIE, 24 T +32 2 649 51 64 BE- 1040 BRUSSELS F +32 2 640 37 30 www.uems.eu [email protected] UEMS 2020.11 Syllabus for residents and trainees in Rare Adult Solid Cancers The basic goal of this syllabus is to provide an understanding between the instructor and trainee so there is minimal confusion in the topics, with clear expectations. It is not a classical syllabus as it contains descriptions from different areas, but it still summarizes major and specific topics that should be covered during the training course of a resident. This syllabus is intended as supporting reference material, and the precise content and priorities of training may vary in different training institutions. The syllabus can also be modified to reflect each instructor's teaching philosophy towards the trainees. 1. There are scientific publications, web pages, and conference materials available online that could be used for educational purposes for various types of rare adult solid cancers. This is a comprehensive summary of them. 2. There are significant differences in the number of available scientific publications and reviews for different rare adult solid cancers. Some, like sarcomas, have a very robust literature, while others have been sparsely researched and consequently the availability of study materials is quite poor. 3. These differences also apply to life events and natural history. In the list of the EU CE accredited events there is a strong underrepresentation for some types of rare adult solid cancers.
    [Show full text]
  • Ct Findings of Hypervascular Malignant Peritoneal Mesothelioma
    Compurerized Radial. Vol. I I, No. 2, pp. 91-94, 1987 0730-4862/87 53.00 + 0.00 Printed in the U.S.A. All rights reserved Copyright 8 1987 Pergamon Journals Ltd CT FINDINGS OF HYPERVASCULAR MALIGNANT PERITONEAL MESOTHELIOMA DEBORAH S. GRANKE,* JAMES H. ELLIS and BRUCE D. RICHMOND Radiology Service (114) Veterans Administration Medical Center and Department of Radiology. University of Michigan Medical School, Ann Arbor, MI 48105. U.S.A. (Received 19 June 1986; in revised form 21 October 1986; received for publicatiorr 6 November 1986) Abstract-A case of peritoneal mesothelioma is presented in which CT demonstrated abnormal regions of increased vascularity in the omentum corresponding to hypervascular omental lesions shown by angiography. This CT appearance has not been described in prior reports of CT in peritoneal mesothelioma. Mesothelioma. peritoneal Angiography Computed tomography INTRODUCTION Reports of computed tomography (CT) in mesothelioma describe peritoneal involvement that may be extensive, with confluent tumor in layers, masses, and/or nodules and mesenteric infiltration [l, 21. A recent report of anteriography in peritoneal mesothelioma described three cases of mildly to moderately hypervascular omental lesions without arteriovenous shunting; however, the one CT scan performed was nondiagnostic [3]. We report a case of peritoneal mesothelioma where CT demon- strated abnormal regions of increased vascularity in the omentum corresponding to the hypervascular omental lesions shown by angiography. CASE REPORT A 54-year-old white male presented with a 3-month history of insidious onset of diffuse abdominal tenderness, early satiety, abdominal bloating, and crampy abdominal pain. His physical exam was unremarkable, and routine laboratory tests, sigmoidoscopy, and barium enema were normal.
    [Show full text]
  • Antitumor Activity of Mir-34A in Peritoneal Mesothelioma Relies on C-MET and AXL Inhibition
    El Bezawy et al. Journal of Hematology & Oncology (2017) 10:19 DOI 10.1186/s13045-016-0387-6 RESEARCH Open Access Antitumor activity of miR-34a in peritoneal mesothelioma relies on c-MET and AXL inhibition: persistent activation of ERK and AKT signaling as a possible cytoprotective mechanism Rihan El Bezawy1, Michelandrea De Cesare1, Marzia Pennati1, Marcello Deraco2, Paolo Gandellini1, Valentina Zuco1*† and Nadia Zaffaroni1*† Abstract Background: The value of microRNAs (miRNAs) as novel targets for cancer therapy is now widely recognized. However, no information is currently available on the expression/functional role of miRNAs in diffuse malignant peritoneal mesothelioma (DMPM), a rapidly lethal disease, poorly responsive to conventional treatments, for which the development of new therapeutic strategies is urgently needed. Here, we evaluated the expression and biological effects of miR-34a—one of the most widely deregulated miRNAs in cancer and for which a lipid-formulated mimic is already clinically available—in a large cohort of DMPM clinical samples and a unique collection of in house-developed preclinical models, with the aim to assess the potential of a miR-34a-based approach for disease treatment. Methods: miR-34a expression was determined by qRT-PCR in 45 DMPM and 7 normal peritoneum specimens as well as in 5 DMPM cell lines. Following transfection with miR-34a mimic, the effects on DMPM cell phenotype, in terms of proliferative potential, apoptotic rate, invasion ability, and cell cycle distribution, were assessed. In addition, three subcutaneous and orthotopic DMPM xenograft models were used to examine the effect of miR-34a on tumorigenicity. The expression of miRNA targets and the activation status of relevant pathways were investigated by western blot.
    [Show full text]
  • Desmoplastic Small Round Cell Tumor of the Abdomen: a Case Report and Literature Review of Therapeutic Options
    Vol.4, No.4, 207-211 (2012) Health http://dx.doi.org/10.4236/health.2012.44031 Desmoplastic small round cell tumor of the abdomen: A case report and literature review of therapeutic options Hafida Benhammane1*, Leila Chbani2, Abdelmalek Ousadden3, Ouadii Mouquit3, Siham Tizniti4, Afaf Riffi Amarti2, Nouafal Mellas1, Omar El Mesbahi1 1Department of Medical Oncology, Hassan II University Hospital, Fez, Morocco; *Corresponding Author: [email protected] 2Department of Pathology, Hassan II University Hospital, Fez, Morocco 3Department of General Surgery, Hassan II University Hospital, Fez, Morocco 4Department of Radiology, Hassan II University Hospital, Fez, Morocco Received 22 December 2011; revised 18 January 2012; accepted 6 February 2012 ABSTRACT rent therapeutic options include multiagent chemothe- rapy and aggressive surgical debulking and radiotherapy Desmoplastic small round cell tumor (DSRCT) is [4,5]. The addition of hyperthermic intra-peritoneal che- a rare and highly aggressive variety of sarcoma motherapy in the multimodal approach has been reported arising typically from abdominal or pelvic peri- in very few cases but no effect on survival has been clearly toneum. Diagnosis and treatment approaches of demonstrated [6]. this entity are complex and require a skilled, ex- The prognosis of this disease is poor with a Median perienced, multidisciplinary team. Authors re- survival of 17 months approximately [7]. port their experience with a case of an intra-ab- We report a case of an intra-abdominal DSRCT in a 37 dominal DSRCT arising in a 37-year-old young -year-old young man who was treated with combination man in order to discuss the clinico-pathological chemotherapy and surgery.
    [Show full text]
  • "Gastrointestinal Tract Pathology"
    IIC,J CALIFORNIA TUMOR TISSUE REGISTRY "GASTROINTESTINAL TRACT PATHOLOGY" Study Cases, Subscription A March 2000 California Tumor Tissue Registry c/o: De1mrtment of Pathology and Human Anatomy Loma Linda Univcr.;ily School ofMcd.icine 11021 Campus Avenue, AH 335 Lomn Linda, California 92350 (909) 558-4788 FAX: (909) 558·0188 E-mail: [email protected] Case oftbe Month: www.llu.edu/Uu/cttr/cotm Target audience: Practicing pathologists and pathology residents. Goal: To acquairu the participam with the hiswlogic featu res of a variety of benign and malignant neoplasms and tumor-l ike conditions. Objectives: n1e participant will be able to recognize morphologic features ofa variety of benign and malignam neoplasms and tWllOr-like conditions and relate those processes to pertinent references in d1e medical literature. Educational methods and media: Review of representative glass slides v.ith associated histories. Feedback on consensus diagnoses lt·om participating pathologists. Listing of selected references from the medical literature. Principal faculty: Weldon K. Bullock, Ml) Donald R. Chase, MD CME Credit: Lorna Li.nda University School of Medicine designates this continuing medical education·activity for up to 2 hours of Category I of the Physician's Recogn ition Award oft he· American Medical Association. CME credit is offered for d1e subscription year only. Accreditation: Loma Linda University School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to sponsor continuing medical education for physicians. Contributor: James A. Henry, M.D. Case No. 1 - March 2000 Woodbridge, VA Tissue from: Terminal ileum Accession #28502 Clinical Abstract: This 37-year-old black female presented with several weeks' history of right lower quadrant abdominal pain radiating to the right side of the back and right inguinal area.
    [Show full text]
  • The State of Sex: Tourism, Sex and Sin in the New American Heartland
    THE STATE OF SEX The State of Sex is a study of Nevada’s legal brothels that situates the nation’s only legal brothel industry in the political economy of con- temporary tourism. Nevada is part of the “new American heartland,” as its pastimes, people, and politics have become more central to the nation. The rise of a service and leisure economy over the past 60 years has propelled sexuality into the heart of contemporary markets. Yet, neoliberal laws in the United States promote business but limit sexual commerce. How have Nevada’s legal brothels survived, while the rest of the country criminalizes prostitution? How do the brothels operate? Who works in them? This book brings social theory on globalizing econ- omies, politics, leisure consumption, and emotional labor in interactive service work together with research on contemporary prostitution and sexual commerce. The authors employ an innovative, multi-method sociological approach, combining historical analysis of how the brothels came to be with over a decade’s worth of ethnographic research on the current state of the industry. Barbara G. Brents, Ph.D., is Associate Professor of Sociology and Faculty Affiliate in Women’s Studies at the University of Nevada, Las Vegas. Crystal A. Jackson, M.A., is a Ph.D. student in the Department of Sociology at the University of Nevada, Las Vegas. Kathryn Hausbeck, Ph.D., is Senior Associate Dean of the Graduate College and Associate Professor in Sociology at the University of Nevada, Las Vegas. Edited by Valerie Jenness, University of California–Irvine and Jodi O’Brien, Seattle University This innovative series is for all readers interested in books that provide frameworks for making sense of the complexities of contemporary social life.
    [Show full text]
  • Localized Biphasic Malignant Peritoneal Mesothelioma with Rhabdoid Features Involving the Liver: Case Report and Review of the Literature
    Hindawi Case Reports in Pathology Volume 2019, Article ID 2732674, 7 pages https://doi.org/10.1155/2019/2732674 Case Report Localized Biphasic Malignant Peritoneal Mesothelioma with Rhabdoid Features Involving the Liver: Case Report and Review of the Literature Dalal Hassan and Saverio Ligato Department of Pathology and Laboratory Medicine, Hartford Hospital, Hartford, CT, USA Correspondence should be addressed to Dalal Hassan; [email protected] Received 24 April 2019; Accepted 15 July 2019; Published 28 July 2019 Academic Editor: Fatemeh Mahjoub Copyright © 2019 Dalal Hassan and Saverio Ligato. Tis is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Introduction. Localized malignant mesotheliomas, defned as sharply circumscribed tumors of the serosal membrane with the microscopic appearance of difuse malignant mesothelioma, are rare tumors; their behavior and prognosis are uncertain. Intrahepatic mesotheliomas are postulated to arise from mesothelial cells of Glisson’s capsule. Case Presentation.A69-year-old female with no history of asbestos exposure presented with a one-month history of increasing abdominal pain associated with constitutional symptoms. Computerized Tomography (CT) scan of the abdomen and pelvis revealed a sizable sof tissue mass within the right paracolic gutter, abutting the inferior hepatic margin, the lateral abdominal wall, and descending colon. Ultrasound- guided biopsy of the mass suggested a poorly diferentiated hepatocellular carcinoma. Tere was no disease elsewhere on PET scan. Surgical resection of the mass was performed. Pathological assessment suggested the tumor to be arising from the liver with invasion of the liver, abdominal wall musculature, and the adventitial surface of the ascending colon.
    [Show full text]
  • Rare Epithelial Tumours of the Digestive System 17 532
    RARE EPITHELIAL TUMOURS OF THE 16 % OF DIGESTIVE SYSTEM TUMOURS ARE RARE DIGESTIVE SYSTEM EPITHELIAL TUMOURS 2 262 EPITHELIAL TUMOURS OF OESOPHAGUS 81 % OF RARE EPITHELIAL TUMOURS 271 RARE EPITHELIAL TUMOURS 1 OUT OF ALL TUMOURS OF STOMACH IN EACH SITE 696 EPITHELIAL TUMOURS OF SMALL INTESTINE 56 87 RARE EPITHELIAL TUMOURS <1 INCIDENCE OF COLON 17 532 97 RARE EPITHELIAL TUMOURS OF RECTUM 1 ESTIMATED NEW CASES 1 143 EPITHELIAL TUMOURS OF ANAL CANAL 97 ITALY, 2015 RARE EPITHELIAL TUMOURS 71 OF PANCREAS 1 EPITHELIAL TUMOURS OF LIVER 7 291 AND INTRAHEPATIC BILE TRACT 53 EPITHELIAL TUMOURS OF GALLBLADDER 5 483 AND EXTRAHEPATIC BILIARY TRACT 99 132 MESOTHELIOMA OF PERITONEUM PREVALENCE SURVIVAL 43 452 100% ESTIMATED PREVALENT CASES ITALY, 2010 50% 20% 0 1 5 YEARS AFTER DIAGNOSIS SOURCE: AIRTUM. ITALIAN CANCER FIGURES–REPORT 2015 RARE EPITHELIAL TUMOURS OF THE DIGESTIVE SYSTEM I tumori in Italia • Rapporto AIRTUM 2015 INCIDENCE RARE EPITHELIAL TUMOURS OF THE DIGESTIVE SYSTEM. Crude incidence (rate per 100,000/year) and 95% confidence interval (95% CI), observed cases and proportion of rare cancers on all (common + rare) cancers by site. Rates with 95% CI by sex and age. Estimated new cases at 2015 in Italy. AIRTUM POOL (period of diagnosis 2000-2010) ITALY SEX AGE MALE FEMALE 0-54 yrs 55-64 yrs 65+ yrs ESTIMATED NEW CASES RATE 95% CI RATE 95% CI RATE 95% CI RATE 95% CI RATE 95% CI RATE 95% CI 2015 OBSERVED CASES OBSERVED (No.) EPITHELIAL RARE SITE BY CANCERS (%) RARE EPITHELIAL TUMOURS 26.11 25.89-26.32 57 891 16% 32.11 31.78-32.45 20.48 20.22-20.74
    [Show full text]
  • Presentation of a Malignant Peritoneal Mesothelioma in the Form of Rough
    1130-0108/2017/109/5/374 REVISTA ESPAÑOLA DE ENFERMEDADES DIGESTIVAS REV ESP ENFERM DIG © Copyright 2017. SEPD y © ARÁN EDICIONES, S.L. 2017, Vol. 109, N.º 5, pp. 374 PICTURES IN DIGESTIVE PATHOLOGY Presentation of a malignant peritoneal mesothelioma in the form of rough hepatic calcifications Carmen Lara-Romero, Aida Casado-Bernabéu and Eduardo Romero-Pérez Department of Digestive Diseases. Hospital Universitario Virgen de la Victoria. Málaga, Spain The malignant peritoneal mesothelioma is a strange type of tumor that affects the peritoneal serosa, making up 10% of all mesotheliomas. Similar to the pleural mesothelioma, it is associated with industrial pollutants and asbestos, with a latency period of 30 years from exposure. There are no specific signs or symptoms, and it is usually diagnosed at an advanced stage. The most frequent symptoms are pain and abdominal distension, anorexia and weight loss. The localized form of the disease is less frequent and it usually presents itself as a heterogeneous intra-abdominal mass. CASE REPORT Fig. 2. Abdominal TC. We present the case of a 60-year-old hypertensive male, without any other relevant medical history, who attended the Emergency Unit complaining about abdominal disten- sion and asthenia for the past three months. On examination he presented an ascitic abdomen and what felt like a stony mass in the right hypochondrium. The chest X-ray showed other abnormalities (Fig. 1). The abdominal computed a calcified mass on the right hypochondrium, without any tomography (CT) showed a heterogeneous sub-phrenic mass, with calcifications that involved the right hepatic lobe (Fig. 2). Blood tests and tumor markers including alphafetoprotein were normal.
    [Show full text]