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THE DIGESTIVE SYSTEM

The digestive system breaks down and absorbs nutrients the body needs to survive.

The digestive system’s six functions are , motility, , , absorption, and elimination. ALIMENTARY, MY DEAR WATSON

To survive and perform its functions, the body needs specificmacromolecules (, , and lipids) as well as water, vitamins, and minerals.

The digestive system breaks the macromolecules down into smaller molecules the body can use. Carbohydrates break down from and into (like ), lipids break down from into fatty and molecules, and proteins break down into amino acids. 2

SET MUSCLES TO AUTOMATIC

RECTUM The plays a key role in digestion. is the name for the involuntary muscle movements that keep moving through your intestines. ANAL (INTERNAL) Ring-like muscles called serve as “gates” between different parts of the digestive system.

Factoid! Muscle movements in the digestive ANAL SPHINCTER system are controlled by the enteric (EXTERNAL) (ENS), a part of the (ANS). TEETH SALIVARY THE BIG GLANDS PICTURE: ORAL CAVITY THE GI TRACT

ESOPHAGUS The (GI Tract), also referred to as the digestive tract or alimentary canal, includes the oral cavity, pharynx, , stomach, , , and . The accessory digestive organs (salivary LARGE glands, liver, gallbladder, and pancreas) SMALL INTESTINE work in conjunction with the GI tract. INTESTINE The teeth and tongue allow us to mechanically break down and swallow ANUS our food.

4 THE ORAL CAVITY HARD

The is where ingestion happens. Food and drink enter the GI tract through the oral cavity. TONGUE The teeth break solids into smaller pieces and the salivary glands secrete that begin breaking down the food.

The tongue begins the SALIVARY GLANDS process by pushing the -covered OROPHARYNX food () against the and towards the oropharynx. LARYNGOPHARYNX

ESOPHAGUS 5 NASOPHARYNX PHARYNX & ESOPHAGUS

In the pharyngeal phase of swallowing (involuntary), the oropharynx, the ORAL , and uvula close off the SOFT PALATE CAVITY (ROOF OF nasopharynx, starting the swallowing MOUTH) reflex.

In the esophageal phase (involuntary), muscle contractions in the esophagus TONGUE UVULA take the bolus to the stomach. This takes five to eight seconds. LARYNGOPHARYNX ESOPHAGUS Factoid! The transition from the pharynx to the esophagus takes only one second.

6 SEROSA ESOPHAGUS LOWER ESOPHAGEAL THE STOMACH SPHINCTER MUCOSA MUSCLE The stomach is where the bolus is LAYERS mixed with gastric juice to form . PYLORIC The stomach’s interior is extremely SPHINCTER acidic. It also contains an called , which helps with the breakdown (digestion) of proteins. Ingested nutrients typically spend two to six hours in the stomach. Factoid! reflux (aka gastroesophageal reflux or heartburn) occurs when acid from the stomach escapes back up into the esophagus. 7 LIVER THE LIVER &

GALLBLADDER COMMON GALLBLADDER DUCT

The main digestive function of the liver is to produce bile, which aids in the mechanical digestion of lipids in the small intestine, allowing for more efficient chemical digestion of triglycerides.

The gallbladder stores, concentrates, and releases bile that the liver produces. Factoid! You can live without a gallbladder! Cholecystectomy (gallbladder removal) is a common surgical procedure for patients with painful gallstones. 8

THE PANCREAS

The pancreas has exocrine and endocrine cells.

The endocrine cells produce and secrete such as , which helps regulate glucose levels, and glucagon, which helps the liver convert to glucose.

The exocrine cells produce digestive enzymes in a to assist with digestive activities for proteins, carbohydrates, and fats.

9 HEPATIC PORTAL (+ BRANCHES) THE SMALL DUODENUM INTESTINE

Chyme moves from the stomach into the small intestine, where it spends JEJUNUM about 12 hours. The small intestine has three sections: the duodenum, the jejunum, and the .

In the small intestine, from the accessory glands further the breakdown of macromolecules. The products of this breakdown are absorbed along with vitamins, minerals, and water. Blood vessels in the walls of the small intestine carry absorbed nutrients to the liver via the ILEUM hepatic portal vein. 10 TRANSVERSE COLON THE LARGE ASCENDING COLON INTESTINE & ANUS

The small intestine empties into the large intestine (colon), where the remainder of absorption of water, DESCENDING COLON electrolytes, and vitamins occurs.

The remaining undigested food is converted into a solid called , which moves through the large SIGMOID COLON intestine and the and is RECTUM ultimately eliminated (leaves the body) through the anus. ANAL SPHINCTERS “Food” spends about 6 hours in the colon.

ANAL CANAL 11 APPENDIX: THE APPENDIX

Attached to the cecum is a tiny called the appendix.

Though its function is largely vestigial, the appendix interacts with the digestive system by serving as a reservoir for gut . Research has also shown that the appendix plays a role in the in adults and the in embryos. CECUM If it becomes infected, the appendix is APPENDIX usually removed. Like the gallbladder and , many people live without it.

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