C4BPA ODC1 FGG HBG1 SIAT9 CYP24
Primary Resource for Searching the Genome: UCSC Genome Data Center http://genome.ucsc.edu/cgi-bin/hgGateway
C4BPA • On which chromosome is this gene located? chr1:207277607-207318308
• How many exons does it contain? Twelve (12).
• By what name is the gene or gene product commonly known? Complement component 4 binding protein, alpha
• What is the primary function of the gene or gene product, and in which tissue is it expressed, if known? It is part of the complement system, a portion of the immune system that is used to fight infections. It seems to be highly expressed in the liver
Bio 0200 Scavenger Hunt Answer Key Page 1
ODC1 • On which chromosome is this gene located? chr2:10580508-10588453
• How many exons does it contain? 12 (8 coding exons)
• By what name is the gene or gene product commonly known? Ornithine decarboxylase
• What is the primary function of the gene or gene product, and in which tissue is it expressed, if known? It seems to be heavily expressed in blood-forming tissues.
FGG
• On which chromosome is this gene located? chr4:155,525,287-155,533,902
• How many exons does it contain? 7 (3 coding exons)
• By what name is the gene or gene product commonly known? Fibrinogen (gamma component)
• What is the primary function of the gene or gene product, and in which tissue is it expressed, if known?
Fibrinogen is a soluble protein found in blood plasma, and is associated with the clotting reaction. Most of the fibrinogen in circulation is produced by the liver.
Bio 0200 Scavenger Hunt Answer Key Page 2 HBG1
• On which chromosome is this gene located? chr11:5,269,502-5,276,395
• How many exons does it contain? 3 exons
• By what name is the gene or gene product commonly known? A-gamma-globin
• What is the primary function of the gene or gene product, and in which tissue is it expressed, if known? It is one of the polypeptides found in the fetal form of hemoglobin. Like all hemoglobins, it is synthesized by red blood cells (erythrocytes).
SIAT9
• On which chromosome is this gene located? chr2:86,066,271-86,094,793
• How many exons does it contain? Seven (7)
• By what name is the gene or gene product commonly known? It has a complex name: ST3 beta-galactoside alpha-2,3-sialyltransferase. The protein product is also known as Sialyltransferase 9 (SIAT9)
• What is the primary function of the gene or gene product, and in which tissue is it expressed, if known? This is an enzyme that attaches sugars to certain proteins as they pass through the Golgi apparatus. Defects in this gene are associated with Amish infantile epilepsy syndrome.
Bio 0200 Scavenger Hunt Answer Key Page 3
CYP24
• On which chromosome is this gene located? chr20:52,769,988-52,790,516
• How many exons does it contain? 11 exons (10 coding exons)
• By what name is the gene or gene product commonly known? cytochrome P450
• What is the primary function of the gene or gene product, and in which tissue is it expressed, if known? It produces an enzyme associated with vitamin D metabolism. It is located within mitochondria of tissues throughout the body.
Bio 0200 Scavenger Hunt Answer Key Page 4