Physical Assessment for Pharmacists �������������������������������������������� 31 Elizabeth Glashan, Theresa Eberhardt, and Sherif Hanafy Mahmoud
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Clinical Pharmacy Specialist
SAMPLE JOB DESCRIPTION Clinical Pharmacist Specialist I. JOB SUMMARY The Clinical Pharmacist Specialists are responsible and accountable for the provision of safe, effective, and prompt medication therapy. Through various assignments within the department, they provide support of centralized and decentralized medication-use systems as well as deliver optimal medication therapy to patients with a broad range of disease states. Clinical Pharmacist Specialists proficiently provide direct patient-centered care and integrated pharmacy operational services in a decentralized practice setting with physicians, nurses, and other hospital personnel. These clinicians are aligned with target interdisciplinary programs and specialty services to deliver medication therapy management within specialty patient care services and to ensure pharmaceutical care programs are appropriately integrated throughout the institution. In these clinical roles, Clinical Pharmacist Specialists participate in all necessary aspects of the medication-use system while providing comprehensive and individualized pharmaceutical care to the patients in their assigned areas. Pharmaceutical care services include but are not limited to assessing patient needs, incorporating age and disease specific characteristics into drug therapy and patient education, adjusting care according to patient response, and providing clinical interventions to detect, mitigate, and prevent medication adverse events. Clinical Pharmacist Specialists serve as departmental resources and liaisons to other -
Folic Acid Antagonists: Antimicrobial and Immunomodulating Mechanisms and Applications
International Journal of Molecular Sciences Review Folic Acid Antagonists: Antimicrobial and Immunomodulating Mechanisms and Applications Daniel Fernández-Villa 1, Maria Rosa Aguilar 1,2 and Luis Rojo 1,2,* 1 Instituto de Ciencia y Tecnología de Polímeros, Consejo Superior de Investigaciones Científicas, CSIC, 28006 Madrid, Spain; [email protected] (D.F.-V.); [email protected] (M.R.A.) 2 Consorcio Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina, 28029 Madrid, Spain * Correspondence: [email protected]; Tel.: +34-915-622-900 Received: 18 September 2019; Accepted: 7 October 2019; Published: 9 October 2019 Abstract: Bacterial, protozoan and other microbial infections share an accelerated metabolic rate. In order to ensure a proper functioning of cell replication and proteins and nucleic acids synthesis processes, folate metabolism rate is also increased in these cases. For this reason, folic acid antagonists have been used since their discovery to treat different kinds of microbial infections, taking advantage of this metabolic difference when compared with human cells. However, resistances to these compounds have emerged since then and only combined therapies are currently used in clinic. In addition, some of these compounds have been found to have an immunomodulatory behavior that allows clinicians using them as anti-inflammatory or immunosuppressive drugs. Therefore, the aim of this review is to provide an updated state-of-the-art on the use of antifolates as antibacterial and immunomodulating agents in the clinical setting, as well as to present their action mechanisms and currently investigated biomedical applications. Keywords: folic acid antagonists; antifolates; antibiotics; antibacterials; immunomodulation; sulfonamides; antimalarial 1. -
Hadrian and the Greek East
HADRIAN AND THE GREEK EAST: IMPERIAL POLICY AND COMMUNICATION DISSERTATION Presented in Partial Fulfillment of the Requirements for the Degree Doctor of Philosophy in the Graduate School of the Ohio State University By Demetrios Kritsotakis, B.A, M.A. * * * * * The Ohio State University 2008 Dissertation Committee: Approved by Professor Fritz Graf, Adviser Professor Tom Hawkins ____________________________ Professor Anthony Kaldellis Adviser Greek and Latin Graduate Program Copyright by Demetrios Kritsotakis 2008 ABSTRACT The Roman Emperor Hadrian pursued a policy of unification of the vast Empire. After his accession, he abandoned the expansionist policy of his predecessor Trajan and focused on securing the frontiers of the empire and on maintaining its stability. Of the utmost importance was the further integration and participation in his program of the peoples of the Greek East, especially of the Greek mainland and Asia Minor. Hadrian now invited them to become active members of the empire. By his lengthy travels and benefactions to the people of the region and by the creation of the Panhellenion, Hadrian attempted to create a second center of the Empire. Rome, in the West, was the first center; now a second one, in the East, would draw together the Greek people on both sides of the Aegean Sea. Thus he could accelerate the unification of the empire by focusing on its two most important elements, Romans and Greeks. Hadrian channeled his intentions in a number of ways, including the use of specific iconographical types on the coinage of his reign and religious language and themes in his interactions with the Greeks. In both cases it becomes evident that the Greeks not only understood his messages, but they also reacted in a positive way. -
295 Emanuela Borgia (Rome) CILICIA and the ROMAN EMPIRE
EMANUELA BORGIA, CILICIA AND THE ROMAN EMPIRE STUDIA EUROPAEA GNESNENSIA 16/2017 ISSN 2082-5951 DOI 10.14746/seg.2017.16.15 Emanuela Borgia (Rome) CILICIA AND THE ROMAN EMPIRE: REFLECTIONS ON PROVINCIA CILICIA AND ITS ROMANISATION Abstract This paper aims at the study of the Roman province of Cilicia, whose formation process was quite long (from the 1st century BC to 72 AD) and complicated by various events. Firstly, it will focus on a more precise determination of the geographic limits of the region, which are not clear and quite ambiguous in the ancient sources. Secondly, the author will thoroughly analyze the formation of the province itself and its progressive Romanization. Finally, political organization of Cilicia within the Roman empire in its different forms throughout time will be taken into account. Key words Cilicia, provincia Cilicia, Roman empire, Romanization, client kings 295 STUDIA EUROPAEA GNESNENSIA 16/2017 · ROME AND THE PROVINCES Quos timuit superat, quos superavit amat (Rut. Nam., De Reditu suo, I, 72) This paper attempts a systematic approach to the study of the Roman province of Cilicia, whose formation process was quite long and characterized by a complicated sequence of historical and political events. The main question is formulated drawing on – though in a different geographic context – the words of G. Alföldy1: can we consider Cilicia a „typical” province of the Roman empire and how can we determine the peculiarities of this province? Moreover, always recalling a point emphasized by G. Alföldy, we have to take into account that, in order to understand the characteristics of a province, it is fundamental to appreciate its level of Romanization and its importance within the empire from the economic, political, military and cultural points of view2. -
The Dancing God and the Mind of Zeus in Nonnos' Dionysiaca
Bard College Bard Digital Commons Senior Projects Spring 2017 Bard Undergraduate Senior Projects Spring 2017 Οὐδε γέρων Ἀστραῖος ἀναίνετο: The Dancing God and the Mind of Zeus in Nonnos’ Dionysiaca Doron Simcha Tauber Bard College, [email protected] Follow this and additional works at: https://digitalcommons.bard.edu/senproj_s2017 Part of the Ancient History, Greek and Roman through Late Antiquity Commons, Classical Literature and Philology Commons, and the Indo-European Linguistics and Philology Commons This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License. Recommended Citation Tauber, Doron Simcha, "Οὐδε γέρων Ἀστραῖος ἀναίνετο: The Dancing God and the Mind of Zeus in Nonnos’ Dionysiaca" (2017). Senior Projects Spring 2017. 130. https://digitalcommons.bard.edu/senproj_s2017/130 This Open Access work is protected by copyright and/or related rights. It has been provided to you by Bard College's Stevenson Library with permission from the rights-holder(s). You are free to use this work in any way that is permitted by the copyright and related rights. For other uses you need to obtain permission from the rights- holder(s) directly, unless additional rights are indicated by a Creative Commons license in the record and/or on the work itself. For more information, please contact [email protected]. Οὐδε γέρων Ἀστραῖος ἀναίνετο The Dancing God and the Mind of Zeus in Nonnos’ Dionysiaca Senior Project submitted to The Division of Languages and Literature of Bard College by Doron Simcha Tauber Annandale-on-Hudson, New York May 2017 For James, my Hymenaios Acknowledgements: Bill Mullen has been the captain of my errant ship, always strong on the rudder to keep my course on line. -
Tetracycline and Sulfonamide Antibiotics in Soils: Presence, Fate and Environmental Risks
processes Review Tetracycline and Sulfonamide Antibiotics in Soils: Presence, Fate and Environmental Risks Manuel Conde-Cid 1, Avelino Núñez-Delgado 2 , María José Fernández-Sanjurjo 2 , Esperanza Álvarez-Rodríguez 2, David Fernández-Calviño 1,* and Manuel Arias-Estévez 1 1 Soil Science and Agricultural Chemistry, Faculty Sciences, University Vigo, 32004 Ourense, Spain; [email protected] (M.C.-C.); [email protected] (M.A.-E.) 2 Department Soil Science and Agricultural Chemistry, Engineering Polytechnic School, University Santiago de Compostela, 27002 Lugo, Spain; [email protected] (A.N.-D.); [email protected] (M.J.F.-S.); [email protected] (E.Á.-R.) * Correspondence: [email protected] Received: 30 October 2020; Accepted: 13 November 2020; Published: 17 November 2020 Abstract: Veterinary antibiotics are widely used worldwide to treat and prevent infectious diseases, as well as (in countries where allowed) to promote growth and improve feeding efficiency of food-producing animals in livestock activities. Among the different antibiotic classes, tetracyclines and sulfonamides are two of the most used for veterinary proposals. Due to the fact that these compounds are poorly absorbed in the gut of animals, a significant proportion (up to ~90%) of them are excreted unchanged, thus reaching the environment mainly through the application of manures and slurries as fertilizers in agricultural fields. Once in the soil, antibiotics are subjected to a series of physicochemical and biological processes, which depend both on the antibiotic nature and soil characteristics. Adsorption/desorption to soil particles and degradation are the main processes that will affect the persistence, bioavailability, and environmental fate of these pollutants, thus determining their potential impacts and risks on human and ecological health. -
Leading by Example
CONNECT WITH US ONLINE /TheRichmondSentinel @TheRichmondSentinel @RmdSentinel richmondsentinel.ca Download our app VOL. 4 ISSUE 8 NOT-FOR-PROFIT MAY 12 - 25, 2020 Leading by example Dedicated student wins prestigious national scholarship 13 Photo submitted Surrounded by her peers in the Free the Children Club team at this year’s We Day, Grade 12 Richmond High student Rita Jin (front row, centre) has earned a prestigious Schulich Leader Scholarship valued at $80,000. ALL REVENUES BOOK ONLINE REINVESTED TO HELP TODAY! ANIMALS & THEIR PEOPLE! rapsanimalhospital.com 2 | CITY NEWS May 12 - 25, 2020 RICHMOND SENTINEL Lawn watering regulations now in effect By HANNAH ScOTT • Trees, shrubs, decorative Local Journalism Initiative reporter planters and flowers (excluding edible plants) can be watered any nnual lawn watering regulations day of the week, anytime using Ain the region took effect on May 1 hand watering or drip irrigation, or and will continue until Oct. 15. from 1 to 9 a.m. using a sprinkler. These restrictions conserve the • Edible plants can be watered region’s high-quality drinking water, anytime. ensuring sufficient water sources Demand for water is highest through to the rainy fall season. during the evening, when people Watering regulations are part of use it for preparing dinner, dish- Metro Vancouver’s Drinking Water washing, laundry and showers. By Conservation Plan. Progressively watering lawns early in the morn- stricter stages of water restrictions ing, peak demand on the water may be implemented as needed system is reduced. based on water supply within the re- Photo via Wikimedia Commons Water restrictions also remind gion. -
Patient Safety Clinical Pharmacy Collaborative (PSPC) Guidebook
GUIDEBOOK Planning and Implementing a Successful Collaborative in a Rural Area How the Eastern Virginia Medical School (EVMS) Patient Safety and Clinical Pharmacy Services Collaborative is changing Pharmacy Services in the Eastern Virginia ACKNOWLEDGEMENTS Thank you to the many people who contributed to this document. We acknowledge the Eastern Virginia Medical School Patient Safety and Clinical Pharmacy Services Collaborative members who initiated the development of this document. Thank you to the participant organizations’ leadership members who consistently supported these efforts. The following individuals provided extensive time, effort and dedication to the development of this document: Judy Wessell Judy A. Wessell MSN, APRN, BC, ACRN, AACRN, AAHIVS. Ms. Wessell has been an HIV Nurse Practitioner for 13 years and a Registered Nurse for greater than 36 years. She received her diploma of Nursing from the Newport Hospital School of Nursing in Newport, RI, her BSN and MSN at Old Dominion University, Norfolk, VA. Ms. Wessell is currently the Nurse Practitioner Supervisor at the Eastern Virginia Medical School (EVMS), Center for Care of Immune Deficiency (C3ID), Infectious Disease Clinic. She is an HIV Health Educator with the EVMS AIDS Resource and Consultation Center, providing professional and community educational programs. She is a member of the quality improvement committee and a member of the EVMS Patient Safety and Clinical Pharmacy Collaborative. Tanya Kearney Tanya K. Kearney, MPA, has eight years of experience as Director for the AIDS Resource Center at Eastern Virginia Medical School. She works with health care providers, community- based AIDS service organizations, government agencies, professional associations and academic and community health care providers, to offer multidisciplinary educational programs on HIV/AIDS and other related topics. -
Designing a Campaign on Topical Steroids Misuse
Ministry Of Higher Education University Of Al-Qadysiah And Scientific Research College Of Pharmacy Designing a Campaign On Topical steroids misuse By: Hussein A. Abdulwahab Ali H. Abd Zaid Supervised By: Dr. Hussein A. Sahib 1 بسمميحرلا نمحرلا هللا ۞ َوقُ ْم َر ِّة ِز ْدَِي ِع ْه ًًب ۞ صدق هللا العظيم 2 List of subjects : Dedication 4 Aim 4 Chapter one : introduction 5 Potency 8 Adverse effects 10 Study on topical steroids 18 Chapter tow : methodology 19 Chapter three : 22 Conclusion discussion recommendations References 25 3 Dedication : We dedicate this work to our families and to the Iraqi army Aim : Is to make a campaign that raise awareness on topical steroids’ misuse and side effects 4 Chapter One Introduction 5 1.1 Introduction 1.1.1 Corticosteroids: Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones. Two main classes of corticosteroids, glucocorticoids and mineralocorticoids , are involved in a wide range of physiologic processes, including stress response, immune response, and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior.[1] Some common naturally occurring steroid hormones are cortisol (C21H30O5), corticosterone (C21H30O4), cortisone (C21H28O5) and aldosterone (C21H28O5). (Note that aldosterone and cortisone share the same chemical formula but the structures are different.) The main corticosteroids produced by the adrenal cortex are cortisol and aldosterone. [2] 1.1.2 Topical steroids: The introduction of topical corticosteroids (TC) by Sulzberger and Witten in 1952 is considered to be the most significant landmark in the history of therapy of dermatological disorders.[3] This historical event was gradually, followed by the introduction of a large number of newer TC molecules of varying potency rendering the therapy of various inflammatory cutaneous disorders more effective and less time consuming. -
Multi-Residual Quantitative Analytical Method for Antibiotics in Sea Food by LC/MS/MS
PO-CON1742E Multi-residual quantitative analytical method for antibiotics in sea food by LC/MS/MS ASMS 2017 TP 198 Anant Lohar, Shailendra Rane, Ashutosh Shelar, Shailesh Damale, Rashi Kochhar, Purushottam Sutar, Deepti Bhandarkar, Ajit Datar, Pratap Rasam and Jitendra Kelkar Shimadzu Analytical (India) Pvt. Ltd., 1 A/B, Rushabh Chambers, Makwana Road, Marol, Andheri (E), Mumbai-400059, Maharashtra, India. Multi-residual quantitative analytical method for antibiotics in sea food by LC/MS/MS Introduction Antibiotics are widely used in agriculture as growth LC/MS/MS method has been developed for quantitation of enhancers, disease treatment and control in animal feeding multi-residual antibiotics (Table 1) from sea food sample operations. Concerns for increased antibiotic resistance of using LCMS-8040, a triple quadrupole mass spectrometer microorganisms have prompted research into the from Shimadzu Corporation, Japan. Simultaneous analysis environmental occurrence of these compounds. of multi-residual antibiotics often exhibit peak shape Assessment of the environmental occurrence of antibiotics distortion owing to their different chemical nature. To depends on development of sensitive and selective overcome this, autosampler pre-treatment feature was analytical methods based on new instrumental used [1]. technologies. Table 1. List of antibiotics Sr.No. Name of group Name of compound Number of compounds Flumequine, Oxolinic Acid, Ciprofloxacin, Danofloxacin, Difloxacin.HCl, 1 Fluoroquinolones 8 Enrofloxacin, Sarafloxacin HCl Trihydrate, -
Clinical Pharmacy in Family Practice
Clinical Pharmacy in Family Practice John P. Geyman, MD One of the innovative directions in family prac services has been high.2 Similar collaborative ef tice during the last several years has been the in forts between family practice and clinical phar troduction of clinical pharmacists into some teach macy have been reported in other medical schools, ing and community practices. This is not surpris such as the Medical University of South Carolina2; ing in view of recent changes in pharmacy educa and in community hospital based family practice tion and practice, which have expanded the clini residencies, such as Family Medicine Spokane in cal training of clinical pharmacists and increased Washington State.4 the range of services which they provide. There With regard to community practices, several are growing numbers of clinical pharmacists in questions are immediately raised concerning this teaching hospitals, outpatient clinics, mental kind of interdisciplinary practice, including ethical health centers, and other institutional settings.1 and economic issues, if dispensing of drugs is to be Although the entry of clinical pharmacists into the carried out; also, logistic and procedural ques relatively smaller group settings of family practice tions; cost-benefit questions; and questions re is still an early trend, the experience to date in garding satisfaction of patients, physicians, and both teaching and community practice settings is pharmacists. Of particular interest in terms of how extremely positive. these questions have been resolved in one practice In this issue of The Journal, Love and his col is the report of Davis and his colleagues of their leagues describe the role and contributions of a experience since 1976 in a rural-suburban family clinical pharmacist in the university based family practice in Lexington, South Carolina.5 This prac practice residency program at the University of tice includes two family physicians and one clin Kentucky. -
Do Too Rél« Boa Da Alfandtxa
opíoPaiollepicau ——— . 11 ^ ,. 1 I I. !■ mm^mmmf^—mmmm Agonola no Brás A8ENCIA RO BOM RETIRO Rui Julle Cenc«l«lo, 47 (tob.) (Tclc'|tli«ni« n. 3.833) Namero «o dl« 100 réit AUKMC1A MU 1UO .. ntrmmdo tOO rél« Boa da Alfandtxa. «« • Sobrado CORREIO P/IULISTANO PROPRIBDADB DE UMA DADS ANONYMA AHHIUNATOHAS KKIl.VtVAO li AMUNIBIHAI.ÃO fnill-Anno Mfflonl Kileilnr Annu . «-«HO finca Ir. Antonto Piado (llJanlo llrlecola) S. Paulo -- Domipgo, iPde maio de 1911 UÍcou| • SaoMairr 2fMm calaa do conelo-H II balho demes oovoiros que, em menos do justificar • sua prole tutella, do quo quo a noção da disciplina se não sggra- IKI o pie e o filho adorado, pela memora' tres annos, presididas por um panüytioa, os proveniontes do o republicano vava oom o preconceito inflexível da hon- vd pajMsgem do seu anniversario natali- ASPECTOS DE PORTUGAL abriram com diligencia a vala para ondo (revelando a sua sur lento falta do ra O soldado, na suo maioria aualpbo- CARTAS CIRIOGAS cio, Decorrida, para bem de todos o falU airomossaram o regimen. I). Carlos, sauda- preparação para o • do poder, ma beto, isonto da prorogativa intelligonto cidade gorai da naçlo na ultima icgunda* do no seu advento ao throno, pelos ropu- nifustada pela auson um projecto si- do livro arbítrio pela educação automáti- feira que passou. Segunda Série biicanoa, como «o primeiro « «mmo», pa- quer do constituição), jora se conaido- ca da caserna. caniinharia. obodionto o rar apto para coar collcgios «leito- passivo, atrás dos oommandsntes. Era At barbaridadei do tUio e a altitude do Nunca se viu semelhante romaria — nem rece ter sido fadado a ser o derradeiro rei mosmo no» clássicos dia» da Ponha —, oomo da sua dynnatia.