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Issue 53 • Fall/Winter 2015 Check out Our Fresh Newsletter Design!
AKC Canine Health Foundation Issue 53 • Fall/Winter 2015 THIS ISSUE AT A GLANCE Dr. Douglas Thamm Receives Asa Mays, DVM Award ............3 CHF Welcomes New CSO .........5 CHF & VetVine Team Up for Webinar Series ..........................6 Distinguished Research Partners to be Honored ........................... 7 2015 National Parent Club Canine Health Conference Recap ..........................................8 Labrador Retriever Club, Inc., to Receive President’s Award ....10 Cold Weather Canine Care ...10 Your Impact: Spontaneous Cancer in Dogs ........................13 Check out our fresh newsletter design! © Copyright 2015 AKC Canine Health Foundation. All rights reserved. Dear Canine Health Supporter: This year, we celebrate the 20th anniversary of the AKC Canine Health Foundation (CHF), a milestone that would not be possible without your commitment to the health of all dogs. Thanks to you, the dogs we love benefit from advances in veterinary medicine, receiving better treatment options and more accurate diagnoses for both common and complex health issues. From laying the groundwork that mapped the canine genome, to awarding grants that eventually led to genetic tests for conditions like Exercise-Induced Collapse and Von Willebrand’s Disease; from working collaboratively with researchers to bring about better understanding and more effective treatments for diseases like cancer, epilepsy and bloat, to being on the forefront of new, promising breakthroughs like stem cell research/regenerative medicine, anti-viral therapy and personalized medicine, your support of CHF has made these breakthroughs possible. As we look toward the future, your gift to CHF is as important as ever. By donating and continuing your commitment to canine health, you help build on the important scientific advances in veterinary medicine and biomedical science, impacting future generations of dogs. -
Canine Breed Predisposition to Cancer
Canine Breed Predisposition to Cancer 1Amalia Saladrigas, 1Adrienne Thom, 2Amanda Koehne, DVM 1Stanford University (Class of 2016), 2Cancer Biology Program, Stanford School of Medicine Introduction Osteosarcoma: large breeds Lymphoma: Golden Retriever Particularly now that pets are living longer, cancer has become a leading 1 cause of death in dogs. Cancer can affect all breeds of dogs, but there are General Information: General Information: some breeds that appear to be at higher risk to certain types of cancer. • Most common primary bone tumor in dogs • Most common tumor of the hematopoietic system in dogs Given the similarities between many human and canine cancers, the domestic • The mean age is 7 years7 • Classification of canine lymphomas follows a similar classification 2 13 dog has been used as a model of spontaneous neoplasia. • It occurs in large and giant breed dogs: Doberman, German Shepherd, Golden scheme to that used for humans Retriever, Great Dane, Irish Setter, Rottweiler and Saint Bernard8 • Golden Retrievers are predisposed • Higher incidence in middle-aged dogs (6-7 years)14 Histiocytic Sarcoma: Bernese Clinical Manifestation: Mountain Dog • Occurs in the metaphysis of long bones, similar to disease in humans Clinical Manifestation: • Most common in proximal humerus, distal femur, and proximal tibia • Clinical signs are highly variable and reflect the organs involved General Information: • Metastasis usually to lungs and other bones • Lymphadenopathy, anorexia, and lethargy are common • Mean age of onset is 6.5 years -
Application 2959, Granted, June 2019. To
Report to: Mike Eastwood Countryside Access Team Leader, for Approval of recommendation Date: 13th May 2019 Title: The Commons Act 2006 Section 22 – non-registration of land under the 1965 Commons Registration Act The Commons Registration (England) Regulations 2014 Application 2959 – To register 0.429 hectares of land at Viscar Common, Carnkie, in the parish of Wendron as common land Divisions Affected Wendron Author: Martin Wright Role: Commons and Greens Registration Officer Contact: Tel: 01872 224773 E-mail: [email protected] Recommendation: The application be granted. - 1 - Plan of land sought to be registered as common land: - 2 - 1. Introduction: Cornwall Council has a duty under Section 4 of the Commons Act 2006 to keep a register of common land and a register of town and village greens. Cornwall Council also has a duty under paragraph 26 of the Commons Registration (England) Regulations 2014 to determine applications to amend the registers of common land and town and village greens, unless the registration authority has an interest in the outcome of the application such that there is unlikely to be confidence in the authority’s ability impartially to determine it. Commons Registration Application No. 2959 was made by the Open Spaces Society seeking to register 0.429 hectares of land at Viscar Common as common land under Schedule 2.4 of the Commons Act 2006. This report examines the submitted evidence as to whether the application meets the statutory tests set out in Schedule 2.4 of the Commons Act 2006. The report has been prepared to be presented to a delegated officer. -
TRADES. (CORN \Raj L
464 FAR TRADES. (CORN \rAJ L. FARlllERS continued. Retallack Charles, Higher Dreynes, St. Richards Mrs. Elizabeth, Gover, St. Raby John, Hendra, Hessenford, St. Neot, Liskeard Agnes, Sf'orrier S.O Germans S.O Retallack John, Ventongimps, Perran- Richards Mrs. Elizabeth, Trenethick, Raby Richard, Trevibban, Little Pethe· Porth S.O Mount Hawke, Scorrier S.O rick, St. Issey S.O Retallack R. La Feock, St. Feock, Truro RichardsG. Porthcnllum, St.Erth,Hayle Raby S.G.Lancarffe & PenquitE:,Bodmin Retallack William, Higher Trevella, St. Richards Geo. Tresillian, Probus S.O Radcliff Mrs. Anna, Mount Ambrose, Feock, Truro Richards H. Visc,tr,Carnmenellis, Helstn Treleigh, Redruth Rctallick Arthur Hutchings & Son, Pen- Hichards Mrs. Harriett, Mawla, Mount Raddall Francis, Fleardon & Mount davey, Minster, Boscastle S.O Hawke, Scorrier S. 0 Hawke, Lezant, Callington S.O Retallick J. 'fregurrian, St. Columb S.O Richards Henry, Cooksland, Bodmin Rail Samuel, Eathorn,Mabe,Penryn S.O Retallick J. jun. Higher Wdley. Bodmin Richards Henry, Glebe, ~ithney,Helston Rail W. Calamansack, Constantine, Pen- Retallick James, Pentevale, Roche S.O Richards Henry, Kuggar, Grade, Ruan ryn S. 0 Retallick John, Ash will, Linkinhorne, Minor S. 0 Rail William, Rame, Penryn Callington S. 0 Richards Henry, Relubbus Vean, Ralph Mrs. A. Colan, St. Columb S.O Retallick JohnHenry,Treliggon &Mena, Marazion S.O Ralph Mrs. Anne Maria & Son, Tre- Lanivet, Bodmin Richards Humphry, Dairy, St. Ewe, mough, Mabe, Penryn S.O RettallickJsph.Horrows,Bugle,St.Austll Mevagissey S.O Ralph H. Rosenithon,St. Keverne S.O Retallick Joseph, Newhouse, RocheS.O Richards J. Garlidna, Wenclron, Helston Ralph Mrs. M3ry, Carnmarth, St. -
Analysis of Inherited and Somatic Variants to Decipher Canine Complex Traits
Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1454 Analysis of inherited and somatic variants to decipher canine complex traits KATE MEGQUIER ACTA UNIVERSITATIS UPSALIENSIS ISSN 1651-6206 ISBN 978-91-513-0310-9 UPPSALA urn:nbn:se:uu:diva-347165 2018 Dissertation presented at Uppsala University to be publicly examined in B:22, BMC, Husargatan 3, Uppsala, Monday, 21 May 2018 at 13:15 for the degree of Doctor of Philosophy (Faculty of Medicine). The examination will be conducted in English. Faculty examiner: David Sargan (University of Cambridge). Abstract Megquier, K. 2018. Analysis of inherited and somatic variants to decipher canine complex traits. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1454. 67 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-513-0310-9. This thesis presents several investigations of the dog as a model for complex diseases, focusing on cancers and the effect of genetic risk factors on clinical presentation. In Papers I and II, we performed genome-wide association studies (GWAS) to identify germline risk factors predisposing US golden retrievers to hemangiosarcoma (HSA) and B- cell lymphoma (BLSA). Paper I identified two loci predisposing to both HSA and BLSA, approximately 4 megabases (Mb) apart on chromosome 5. Carrying the risk haplotype at these loci was associated with separate changes in gene expression, both relating to T-cell activation and proliferation. Paper II followed up on the HSA GWAS by performing a meta-analysis with additional cases and controls. This confirmed three previously reported GWAS loci for HSA and revealed three new loci, the most significant on chromosome 18. -
Cancer in Dogs
Cancer in Dogs Canine Cancer Facts FACT: Cancer is the leading cause of non-accidental death in dogs. FACT: Lymphoma is the leading cancer diagnosed in dogs. FACT: Nearly 50% of pets over the age of 10 will develop some type of cancer. FACT: The increasing incidence of cancer in dogs is due to longer life spans. What is cancer? Cancer is a single word that encompasses many different types of diseases. Each of these diseases is attributed to the purposeless and uncontrolled growth of cells on or within the body. They are either localized to one part of the body as a visible mass (tumor) or spread throughout (metastasis). Cancer can develop in or from any tissue in the body. Cancer is common in the dog or cat and the rate increases with age. Dogs get cancer at roughly the same rate as humans, while cats get fewer cancers. In one survey, cancer accounted for almost half the deaths of those pets over 10 years of age. There are many different types of cancer, each type named according to the tissue (or part of the body) that it originated. Some cancers have the ability to metastasize (spread) to other parts of the body. Other terms for cancer are malignancy and neoplasia. What causes canine cancer? No one seems to know for sure what causes cancer in our furry friends. Some theories include pesticides, preservatives and fillers used in dog foods; second hand smoke; vaccinations; chronic ehrlichiosis etc. Unfortunately, these are only theories, and have yet to be proven. Since the cause of cancer is not known, prevention is difficult. -
Mast Cell Tumors Phyllis C Glawe DVM MS Diplomate ACVIM, Oncology
Canine Mast Cell Tumors Phyllis C Glawe DVM MS Diplomate ACVIM, Oncology What is a Mast Cell Tumor? Mast Cell Tumors (MCTs) are one of the most common malignant skin tumors in dogs. Mast cells are the cells that normally are associated with allergy responses, such as the swelling and redness that occur with insect stings. In dogs, mast cell tumors typically are located in the skin of the trunk and peripheral limbs. The masses are typically solitary, reddened in color, hairless and occur in middle age/older dogs. They can be itchy and occasionally can present with ulceration on the skin surface. These tumors are malignant due to their tendency to invade deeply into the surrounding tissue and occasionally spread to other organs, such as the lymph nodes, liver and spleen. One of the more interesting features of this cancer is its behavior: MCTs may grow and shrink rapidly due to inflammation caused by mast cells occasional release of histamine and other vasoactive chemicals. How is the Diagnosis Made? The clinical appearance of MCTs can vary, however the tumors are typically relatively straightforward to diagnose with a fine needle aspiration cytology. A biopsy of tissue can also be performed to obtain the diagnosis, if cytology is not definitive. Special stains can be applied to the tissue biopsy sample to identify the cancer cells if necessary. What is meant by “Grade of the Mast cell tumor” and why is it important? “Grade” of the mast cell tumor refers to characteristics of the cancer cells noted within the tissue biopsy specimen. -
The Canine Genome: Discoveries, Applications, and Future Potential
Eastern Kentucky University Encompass Honors Theses Student Scholarship Spring 5-13-2016 The aC nine Genome: Discoveries, Applications, and Future Potential Rachael Lander Eastern Kentucky University, [email protected] Follow this and additional works at: https://encompass.eku.edu/honors_theses Recommended Citation Lander, Rachael, "The aC nine Genome: Discoveries, Applications, and Future Potential" (2016). Honors Theses. 351. https://encompass.eku.edu/honors_theses/351 This Open Access Thesis is brought to you for free and open access by the Student Scholarship at Encompass. It has been accepted for inclusion in Honors Theses by an authorized administrator of Encompass. For more information, please contact [email protected]. EASTERN KENTUCKY UNIVERSITY The Canine Genome: Discoveries, Applications, and Future Potential Honors Thesis Submitted In Partial Fulfillment of the Requirements of HON 420 Spring 2016 By Rachael Marie Lander Faculty Mentor Dr. Patrick J. Calie Department of Biological Sciences ii Abstract The Canine Genome: Discoveries, Applications, and Future Potential Thesis author: Rachael Marie Lander Thesis mentor: Dr. Patrick J. Calie Department of Biological Sciences A frequent question that educators often encounter is: what is the value of learning? Does knowledge have an inherent value, or should there be an economic benefit? The results of the collaborative efforts to determine the nucleotide sequence of the canine genome were used as a platform to assess these thesis statements. A literature review, practical experience in the laboratory, and interviews with several genome scientists of the contributions of the efforts to determine the genome sequence of the domestic dog, and the biomedical contributions that have been made to both canine and human health demonstrate the inherent value of this scientific objective. -
Wendron Parish Council
1477 WENDRON PARISH COUNCIL www.wendronparishcouncil.org.uk C.F.P.Chapman Clerk to the Council Chy Lean St Keverne Road Mawgan Helston TR12 6AY telephone 01326 221648 [email protected] Minutes of the Ordinary Meeting of Wendron Parish Council held on Monday February 13, 2012 at 7:30pm in the Community Hall, Burras. Present: Cllr Mrs C.Lay Cllr C.Mitchell Cllr P.Davidson Cllr Mrs M.Warren Cllr G.Gibson Cllr Mrs Moyle Cllr R.Maddern C.F.P.Chapman (Clerk) Visitors: CCllr Dr Jenkin, Ms L.Bailey (National Trust), Ms M.Foster (Coastline Housing), Mr N.Gordon (National Trust), Mr M.Griffin (Business Development Director of Mansell Construction) Mr and Mrs Pascoe, Mr and Mrs Reed and Mr Tremayne. The Chairman welcomed members and visitors to the February meeting and invited Mr Griffin and Ms Foster to address the Council. Introducing himself Mr Griffin said that he had been employed in the housing sector for most of his working life. He is the Development Director for Mansell Construction and the Chairman of the House Building Federation. He reminded Members of the acute lack of housing throughout the country and in particular in Cornwall. He stated that he was aware of the problems arising from the ambitious project at Rame last year and wondered if anything might be rescued from its ashes. Stated that change is on-going and inevitable, he asked Members if they had a vision for the future of the Parish, if they had identified parishioners’ needs and if there was anything his company could do. -
Canine Oral Malignant Melanoma Adam C
Volume 58 | Issue 2 Article 12 1996 Canine Oral Malignant Melanoma Adam C. Eiler Iowa State University Kimberly R. Cox Iowa State University Follow this and additional works at: https://lib.dr.iastate.edu/iowastate_veterinarian Part of the Neoplasms Commons, and the Small or Companion Animal Medicine Commons Recommended Citation Eiler, Adam C. and Cox, Kimberly R. (1996) "Canine Oral Malignant Melanoma," Iowa State University Veterinarian: Vol. 58 : Iss. 2 , Article 12. Available at: https://lib.dr.iastate.edu/iowastate_veterinarian/vol58/iss2/12 This Article is brought to you for free and open access by the Journals at Iowa State University Digital Repository. It has been accepted for inclusion in Iowa State University Veterinarian by an authorized editor of Iowa State University Digital Repository. For more information, please contact [email protected]. Canine Oral Malignant Melanoma Adam C. Eiler, DVM * Kimberly R. Cox, DVM ** Neoplasia is an all too common find Veterinary Diagnostic Laboratory for histo ing in domestic animals. The oropharyngeal logic examination, confirming a diagnosis of cavity is a common site for the development oral malignant melanoma. Surgical clear of tumors , particularly in dogs. One such tu ance at the margins was incomplete. The mor is oral malignant melanoma which owner was notified of the findings and given occurs with some frequency in dogs but is a guarded prognosis for long-term survival rare in cats.! Hence, the following shall fo due to the possibility oflocal recurrence and cus on canine malignant melanoma. distant metastasis. "Capricorn" died three years following the Case Study initial diagnosis of oral malignant mela noma. -
Dog Cancer Can Be Effectively Treated, Allowing Your Dog to Continue a Healthy, Happy Life
WHAT EVERY DOG OWNER SHOULD KNOW ABOUT CANCER Copyright © 2017 Marc Smith DVM & PET | TAO Holistic Pet Products, LLC All Rights Reserved Feel free to email, tweet, blog, and pass this e-book around the web… but please don’t alter any of its contents when you do. Thanks! pettao.com Copyright © 2017 Marc Smith, DVM & PET | TAO Holistic Pet Products, LLC 1 WHAT EVERY DOG OWNER SHOULD KNOW ABOUT CANCER WHAT EVERY DOG OWNER SHOULD KNOW ABOUT CANCER Dogs get cancer just like people do. Because cancer is so common in dogs, owners must be aware of the signs and symptoms of cancer. If discovered early, many types of dog cancer can be effectively treated, allowing your dog to continue a healthy, happy life. Our goal is to share information with you about the different dog cancer symptoms, dog cancer treatments, and different preventative measures readily available. Attentive owners can spot dog cancer symptoms as soon as they appear and seek veterinary help immediately. Often, early identification of cancer marks the difference between life and death. If your dog experiences any of the symptoms described below, you should seek veterinary care as soon as possible. Although these symptoms are not proof of cancer, all are possible signs of cancer. Remember, the earlier cancer is identified, the better. Copyright © 2017 Marc Smith, DVM & PET | TAO Holistic Pet Products, LLC 2 WHAT EVERY DOG OWNER SHOULD KNOW ABOUT CANCER Evidence of Pain Evidence of pain or obvious limping while your dog is walking, running or playing is often a sign of arthritis, joint, or muscle issues in older dogs. -
Wendron Parish Council
1512 WENDRON PARISH COUNCIL www.wendronparishcouncil.org.uk C.F.P.Chapman Clerk to the Council Chy Lean St Keverne Road Mawgan Helston TR12 6AY telephone 01326 221648 [email protected] Minutes of the Ordinary Meeting of Wendron Parish Council held on Monday September 10, 2012 at 7:30pm in the Community Hall, Burras. Present: Cllr Mrs C.Lay Cllr Mrs M.Warren Cllr P.Davidson Cllr A Tremayne Cllr R.Maddern Cllr C.Mitchell C.F.P.Chapman (Clerk) Visitors: CCllr Dr Jenkin, Mr Baker, Mr Hales, Mr King, Mr Perry and Mr Speck. The Chairman welcomed members and visitors to the September meeting. 1 APOLOGIES FOR ABSENCE Cllr Gibson, Cllr Mrs Mitchell and Cllr Mrs Moyle sent their apologies for absence. 2 CONFIRMATION OF THE MINUTES OF THE LAST MEETINGS Cllr Mitchell proposed, Cllr Mrs Warren seconded, all others in favour that the minutes of the Ordinary Meeting held on Monday August 13, 2012 are a true record and the Chairman signed them as such. 3 MATTERS ARISING AND NOT COVERED ELSEWHERE IN THIS AGENDA There were no matters arising which were not covered on this agenda. 4 CORNWALL COUNCILLOR’S COMMENTS CCllr Dr Jenkin reported that since the last meeting she has • corresponded with a number of officers and residents in relation to highway, planning and enforcement issues within the Parish • been involved in helping to develop the programme for the Hellysardh Festival alongside Harvest Fair and the Carnival • attended a member briefing on Environmental Services Standards at which it became clear that there is not enough money in the budget to continue to manage environmental assets to current standards • attended the Special Environment and Economy Scrutiny Committee which had ‘called in’ the decision of the cabinet not to assess independently the proposed alternative to a large waste incinerator in the centre of Cornwall.