CANCER TREATMENT AND RESEARCH COMMUNICATIONS

AUTHOR INFORMATION PACK

TABLE OF CONTENTS XXX

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• Description p.1 • Abstracting and Indexing p.1 • Editorial Board p.1 • Guide for Authors p.16

ISSN: 2468-2942

DESCRIPTION

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Announcement: From January 2020 Cancer Treatment and Research Communications is an open access journal. Authors who publish in Cancer Treatment and Research Communications will be able make their work immediately, permanently, and freely accessible. Cancer Treatment and Research Communications authors will pay an article publishing charge (APC), have a choice of license options, and retain copyright to their published work.

Cancer Treatment and Research Communications is an international peer-reviewed publication dedicated to providing comprehensive basic, translational, and clinical oncology research. The journal is devoted to articles on detection, diagnosis, prevention, policy, and treatment of cancer and provides a global forum for the nurturing and development of future generations of oncology scientists. Cancer Treatment and Research Communications publishes comprehensive reviews and original studies describing various aspects of basic through clinical research of all tumor types. The journal also accepts clinical studies in oncology, with an emphasis on prospective early phase clinical trials.

Specific areas of interest include basic, translational, and clinical research and mechanistic approaches; cancer biology; molecular carcinogenesis; genetics and genomics; stem cell and developmental biology; immunology; molecular and cellular oncology; systems biology; drug sensitivity and resistance; gene and antisense therapy; pathology, markers, and prognostic indicators; chemoprevention strategies; multimodality therapy; cancer policy; and integration of various approaches. Our mission is to be the premier source of relevant information through promoting excellence in research and facilitating the timely translation of that science to health care and clinical practice.

ABSTRACTING AND INDEXING

. PubMed/Medline

EDITORIAL BOARD

. Co-Editors-in-Chief Vincent Chung, City of Hope, Duarte, California, United States of America Yesim Gökmen-Polar, Emory University Department of Pathology and Laboratory Medicine, Atlanta, Georgia, United States of America

AUTHOR INFORMATION PACK 1 Oct 2021 www.elsevier.com/locate/ctarc 1 Senior Editors Naval Daver, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America Ilkka Ilonen, Helsinki University Hospital Heart and Lung Center, Helsinki, Finland Przemyslaw Twardowski, John Wayne Cancer Institute, Santa Monica, California, United States of America Andrea Wahner-Hendrickson, Mayo Clinic Rochester, Rochester, Minnesota, United States of America Associate Editors Danielle Benedict L. Sacdalan, UP College of Medicine Department of Pharmacology And Toxicology, Manila, Philippines Medical Oncology Ahmet Emre Eskazan, Istanbul University-Cerrahpasa Cerrahpasa Faculty of Medicine, Fatih, Turkey Acute leukemias, acute lymphoblastic leukemia, acute myeloid leukemia, chronic myeloid leukemia, myeloproliferative neoplasms Nebu Abraham George, Regional Cancer Centre Thiruvananthapuram, Thiruvananthapuram, India Head and neck cancers, including thyroid cancer, oral cancers, tobacco related cancers, and thyroid molecular assay Brian Jonas, UC Davis Comprehensive Cancer Center, Sacramento, California, United States of America Acute myeloid leukemia, myelodysplastic syndrome and acute lymphoblastic leukemia Safeena Kulsum, Mazumdar Shaw Medical Foundation, Narayana Health, Bangalore, India Cancer Biology, Chemo-resistance reversal Strategy, Drug Combination, Cell Line Developer Alessandro Rizzo, University of Bologna, Bologna, Italy Biliary tract cancer, cholangiocarcinoma, liver cancer, gastric cancer, renal cell carcinoma, urothelial carcinoma, prostate cancer, uterine leiomyosarcom Aditi Shastri, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York, United States of America Acute myeloid leukemia, myelodysplastic syndromes, targeted therapies in hematologic malignancies, transcription factors/ signaling pathways

International Advisory Review Board Ata Abbasi, Urmia University of Medical Sciences, Urmia, Iran Cancer pathobiology, tumorigenesis, apoptosis, angiogenesis Mohammed Atef Abd El Ghafar Azab, Pace University, New York, New York, United States of America Molecular oncology - Brain tumors Laith Abushahin, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States of America Gastrointestinal Oncology Alfredo Addeo, University Hospitals Geneva, Geneve, Switzerland Thoracic Malignancies, Biomarkes, Ctdna And Liquid Biopsy Elio Adib, Brigham and Women's Hospital, Boston, Massachusetts, United States of America Cancer genomics, epigenetics Pallavi Agarwal, Amity University Amity Institute Of Molecular Medicine & Stem Cell Research, Noida, India Cancer Biology, Epigenetics, Gene Amplification, Cancer biomarkers, Cancer diagnosis, prognosis and treatment, Ovarian cancer, Breast Cancer , DNA Damage and Repair, Post-translational gene regulation Abed Agbarya, Bnai Zion Medical Center, Haifa, Israel Lung Cancer, Immunotherapy, Biological Treatments, Breast Cancer, Palliative treatment in cancer patients, Colon cancer, Cancer molecular profiling Carlos Aguilar, Soria Healthcare Center, Soria, Spain D-dimer and venous thromboembolism, multiple myeloma Mustapha Ahsaini, Hassan II University Hospital in Fez, Fes, Morocco Urology, oncology, laparoscopy, mini-invasive surgery Mehmet Akce, Emory University Winship Cancer Institute, Atlanta, Georgia, United States of America Phase 1 clinical trials, hepatobiliary malignancies, astrointestinal cancers, liver cancer, pancreatic cancer, cholangiocarcinoma, colorectal cancer, gastroesophageal cancer, anal cancer, neuroendocrine cancer Mariam AlHilli, Cleveland Clinic, Cleveland, Ohio, United States of America Ovarian Cancer, Endometrial Cancer, Cervical Cancer, And Vulvar Cancer Kavitha Alapati Drug discovery on different kinds of cancer cell lines, protein purification, natural products and actinobacteria Moustafa Alkhalil, Hamad Medical Corporation, Doha, Qatar head and neck cancer Andrea Angelini, University of Padova Department of Orthopedics and Orthopedic Oncology, Napoli, Italy

AUTHOR INFORMATION PACK 1 Oct 2021 www.elsevier.com/locate/ctarc 2 Musculoskeletal oncology and spine surgery Jeanny B. Aragon-Ching, Virginia Commonwealth University, Richmond, Virginia, United States of America Amiy Arnav, Tata Main Hospital, Thoracic and Gynae Oncology Mili Arora, University of California Davis Medical Center, Davis, California, United States of America Breast Cancer Angel Artal, Miguel Servet University Hospital Medical Oncology Service, Zaragoza, Spain Thoracic malignancies Mehmet Asim Bilen, Winship Cancer Institute of Emory University, Atlanta, Georgia, United States of America Genitourinary Cancers, Clinical Trial, Phase 1 Olutosin A. Awolude, University of Ibadan College of Medicine, Ibadan, Nigeria Preventive Gynaecology Oncology, Risk Reduction Interventions in genetic/familial women cancers, Prevention of HIV/HPV associated genital cancers Warren Bacorro, University of Santo Tomas, Manila, Philippines Brachytherapy, Cervical Cancer, Quality of Life, Head and Neck Cancer Adithya Balasubramanian, Baylor College of Medicine, Houston, Texas, United States of America Hypothermia, Stroke, Sequencing, RNAseq, Nanostring, Cancer Biology, SNP Genotyping, Sanger Sequencing Quim Megías Barrera, University Clinic Hospital of Santiago de Compostela, Santiago de Compostela, Spain Head and neck surgery, Head and neck reconstructive surgery Afsaneh Barzi, City of Hope Comprehensive Cancer Center Duarte, Duarte, California, United States of America gastric cancer Nicolò Matteo Luca Battisti, Royal Marsden NHS Foundation Trust, London, United Kingdom Breast Cancer, Lung Cancer, Geriatric Oncology Jens Bedke, Eberhard Karls University of Tübingen, Department of of Urology, Tübingen, Germany GU Cancer Patrick R Benusiglio, Sorbonne University, Paris, France Genetic susceptibility to cancer, in particular gastric, kidney and lung cancer, Lynch Syndrome, Genetic counseling in Oncology Eijaz Bhat, Zhejiang University Life Science Institute, Hangzhou, China Structural biology, Apoptosis, inflammation, membrane and cytosolic proteins , Cryo- electron microscopy , protein X-ray crystallography , TRAF signaling, Channel / Ion transporter Saveri Bhattarchaya, Sidney Kimmel Cancer Center, Philadelphia, Pennsylvania, United States of America breast and gynecologic cancers Elia Mario Biganzoli, University of Milan, Milan, Italy DNA damage repair, Genomic Instability, Familial breast cancer, Homologous recombination, genotoxic chemotherapies Jelena Bila, University of Belgrade, Belgrade, Serbia Hematology, Multiple myeloma, Amyloidosis, Macroglobulinemia Waldenstrom George Blanck, USF Health Morsani College of Medicine, Tampa, Florida, United States of America MHC class II regulation in tumors, immunogenomics, retinoblastoma protein function, cytoskeletal and ECM related genomics, apoptosis genomics, regulation of signaling pathways by signal amplification, tumor immunology Bernadette Blauensteiner, Medical University of Vienna, Vienna, Austria Animal Models, Colorectal Cancer, Tumor Immunology, Cancer Immunotherapies JL Boormans, Erasmus MC Cancer Centre, Rotterdam, Netherlands Tumors of the urinary tract Gunnar Boysen, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America Biomarkers for lung cancer prevention and therapy , , Elizabeth Breininger, University of Buenos Aires, Buenos Aires, Argentina Bioochemistry, enzyme activity, cell metabolism Christopher Busby, Latvian Academy of Sciences, Rīga, Latvia Radiation Biology, Epidemiology, Radiation Protection, Radiation Measurements, Uranium, Policy, , Raffaele Califano, The Christie NHS Foundation Trust, Manchester, England, United Kingdom small cell lung cancer and non small cell lung cancer , egfr , alk and immunotherapy Emre Can Tüysüz, Lund University, Faculty of Medicine, Malmö, Sweden Chordoma, miRNA, Cancer Stem Cell, Breast Cancer, Glioma, Role of Inflammation in Cancer Progression, Tumor Microenvironment Huynh Cao, Loma Linda University, Loma Linda, California, United States of America Hematologic malignancies (mainly acute myeloid leukemia) Angelo Carella, Hematology Consultant in Private Clinicals in Genova, Milano and Roma Hematology and Bone Marrow Transplantation Martina Catalano, University of Florence, Firenze, Italy

AUTHOR INFORMATION PACK 1 Oct 2021 www.elsevier.com/locate/ctarc 3 lung cancer, genito-urinary cancer, breast cancer Sakti Chakrabarti, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America Medical oncology, GI oncology, Colorectal cancer, Gastric cancer, Esophageal cancer, circulating tumor DNA, Immunotherapy Alcides Chaux, University of the North, Asuncion, Paraguay Genitourinary pathology, data science, statistics, cancer biology, molecular biology, immunohistochemistry, prognosis, prognostic models, machine learning Zhi Cheng, Johns Hopkins University, Baltimore, Maryland, United States of America Head And Neck Cancer, Radiation Oncology Minsig Choi, Stony Brook University Cancer Center, Stony Brook, New York, United States of America Gastrointestinal Cancers And Translational Oncology Research Dr Manish Chomal, HCG Cancer Centre, Jaipur, India High precision radiotherapy, Head &, Neck, Breast, Gynecological, Genito-urinary &, CNS cancers Anatolii Chumak, SI National Research Center for Radiation Medicine of National Academy of Medical Sciences of Ukraine, Kyiv, Ukraine Chronic lymphocytic leucemia/gene of Lypoproteinlipase expression Looi Chung Yeng, Taylor's University, Subang Jaya, Malaysia Natural product, drug screening, molecular biology, cancer development Kevin Conlon, National Cancer Institute, Bethesda, Maryland, United States of America Immunotherapy, cytokine therapy Alberto DAngelo, University of Bath, Bath, United Kingdom pancreatic cancer, gene expression datasets, molecular oncology, cancer immunology Megan E. Daly, University of California, Davis, U.C. Davis Medical Center, Davis, California, United States of America Thoracic Malignancies, Lymphoma, And Head And Neck Cancers, Radiation Oncology; Stereotactic Body Radiotherapy (Sbrt), Intensity Modulated Radiation Therapy (Imrt), And Image Guided Radiation Therapy (Igrt) Faysal Dane, Acibadem Altunizade Hospital, Istanbul, Turkey GI oncology, Breast cancer and GU oncology Dragomir Dardanov, Medical University-Sofia Faculty of Medicine, , Bulgaria Surgical and general oncology, General and abdominal surgery, Coloproctology Biswadeep Das, All India Institute of Medical Sciences Department of Pharmacology, Rishikesh, India Cardio-Oncology, Oncotherapeutics, Molecularly Targeted Therapies in Cancer, Quality of Life in Cancer, Pharmacoepidemiology Millie Das, Stanford University School of Medicine, Stanford, California, United States of America Adult thoracic oncology Bharti Devnani, All India Institute of Medical Sciences, New Delhi, India Oncology, Radiation Oncology, SBRT, Breast cancer, Head and neck cancers, CNS tumors, Cancer Konstantinos Dimas, University of Thessaly Faculty of Medicine, Larisa, Greece Drug discovery and development, drug delivery systems, animal models of cancer (syngeneic, xenografts, GEMM), signaling, small molecules Eloïse Dray, The University of Texas Health Science Center at San Antonio School of Dentistry, San Antonio, Texas, United States of America DNA damage repair, Genomic Instability, Familial breast cancer, Homologous recombination, genotoxic chemotherapies Ana P Drummond-Lage, Faculty of Medical Sciences of Minas Gerais, BELO HORIZONTE, Brazil Melanoma, Cancer Education, Treatment access, Cancer Policies, Quality-of-life Yi Du, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America cancer research, cancer biology, translational cancer research Audrius Dulskas, Vilnius University Faculty of Medicine, Vilnius, Lithuania Colorectal cancer, minimal invasive techniques, quality of life, functional changes Avraham Eisbruch, University of Michigan Department of Radiation Oncology, Ann Arbor, Michigan, United States of America Head and neck cancer, IMRT, QOL Eman Ahmed Elghoroury, National Research Centre, Cairo, Egypt Molecular biology, mRNA, Gene polymorphism, Flow cytometr analysis, PCR, qPCR, clinical pathology, haematology and immunology Anwar Abd Elnaser, The American University in Cairo, New Cairo, Egypt Oncology, gastroenterology, and immunotherapy Emily Esakov, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, United States of America cancer stem cell biology, ovarian cancer, TNBC Ana Faustino, University of Évora, Evora, Portugal

AUTHOR INFORMATION PACK 1 Oct 2021 www.elsevier.com/locate/ctarc 4 animal models of disease, imaging, oncology Rouhi Fazelzad, University Health Network, Toronto, Ontario, Canada Knowledge synthesis reviews (systematic reviews, scoping reviews, rapid reviews) Francisco Winter dos Santos Figueiredo, University Center Health ABC-FMABC, Epidemiology and Data Analysis Laboratory, SANTO ANDRE, Brazil Cancer epidemiology, cancer, social epidemiology, social determinants, public health Luca Filippi, North Hospital, Latina, Italy Nuclear Medicine, Nuclear Oncology, PET/CT, castration-resistant prostate cancer, hepatocellular carcinoma, radioembolization SIRT/TARE, targeted alpha therapy, Theranostics, neuroendocrine tumors Cristian Fiori, University of Turin, Torino, Italy Urology, prostate, kidney, adrenal, bladder cancers Sinem Firtina, Istinye University Department of Molecular Biology and Genetics, İstanbul, Turkey Leukemia, B-ALL, T-ALL, Next Generation Sequencing Gianluca Franceschini, University Hospital Agostino Gemelli, Rome, Italy Breast Cancer, Surgical Treatment, Oncoplastic Techniques Matthew Galsky, MOUNT SINAI HOSPITAL, New York, New York, United States of America Metastatic Kidney Cancer and Medical Therapy, Radiation Oncology Thomas Gardner, Indiana University Bloomington, Bloomington, Indiana, United States of America Urologic Oncology, clinical trials, medical devices, molecular imaging Manoj Garg, Amity University Amity Institute Of Molecular Medicine & Stem Cell Research, Noida, India Cancer Biology, Cancer genomics, Long non-coding RNA, Xenograft and Patient Derived Xenograft Models, shRNA and Drug screening, Cancer stem cells, Drug resistance Sefonias Getachew, Addis Ababa University, Addis Ababa, Ethiopia Epidemiology, health system, risk factors, interventional and observational studies Michele Ghidini, IRCCS Maggiore Hospital, Ospedale Maggiore Policlinico, Milan, Italy Gastrointestinal cancers, gastric cancer, liver cancer, colorectal cancer, pancreatic cancer, esophageal cancer Sarah Goldberg, Yale Cancer Center, New Haven, Connecticut, United States of America thoracic oncology Juan Luis Gomez Marti, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America Metastatic breast cancer, Tumor dormancy. Tumor biology, Prenylation, , Ana Cristina Gonçalves, University of Coimbra Faculty of Medicine, Coimbra, Portugal Oncobiology, Epigenetics, Genetics, DNA damage repair, Oxidative stress, Biomarker, Targeted therapy, Drug resistance Wilson I. Gonsalves, Mayo Clinic Rochester, Rochester, Minnesota, United States of America Plasma Cell Disorders/Malignancies, Hematologic Malignancies, Cancer Metabolism And Metabolomics Giovanni Grandi, University Hospital Modena, Modena, Italy Ovarian cancer, Hereditary ovarian cancer, BRCA, endometrial cancer prevention, Hereditary uterine cancer, mismatch-repair, cervical cancer Alexandru Calin Grigorescu, Hospital of Nephrology Dr Carol Davila, Bucureşti, Romania Medical Oncology, Palliative care Petros Grivas, University of Washington School of Medicine, Seattle, Washington, United States of America Genitourinary Cancers Sebastian Grosicki, Medical University of Silesia, Faculty of Health Sciences in Bytom, Department of Hematology and Cancer Prevention in Chorzow, Katowice, Poland Hematology, internal medicine, therapy and diagnostics of multiple myeloma, acute leukemias, chronic leukemias Shuchi Gulati, University of Cincinnati, Cincinnati, Ohio, United States of America Genitourinary Cancers Ritu Gupta, All India Institute of Medical Sciences, New Delhi, India Diagnostic Hemato-Oncology, Multiple myeloma, Flow cytometry, Acute leukemia, Image processing, CLL Shilpa Gupta, Cleveland Clinic, Cleveland, Ohio, United States of America Kidney Cancer, Prostate Cancer, Bladder Cancer, Immunotherapy, Experimental Therapeutics, Targeted Therapies Ken H. Young, Duke University Medical Center, Durham, North Carolina, United States of America Diagnosis of hematologic cancers, lymphoma and myeloma pathology,molecular and genetic biomarkers for classification of blood cancer and lymphoid neoplasms, all types of leukemia, myeloid neoplasm, lymphoma, myeloma and benign hematologic disorders, acute and chronic leukemia, myelodysplastic syndromes, myeloproliferative disorders, anemias and cytopenia, benign bone marrow and lymph node disorders, B-cell lymphomas and T-cell lymphomas and cutaneous

AUTHOR INFORMATION PACK 1 Oct 2021 www.elsevier.com/locate/ctarc 5 lymphomas, molecular diagnostics, flow cytometry, cytogenetic and FISH analysis and specialized bone marrow testing Andrew Hahn, University of Texas MD Anderson Cancer Center, Division of Cancer Medicine, Houston, United States of America Advanced prostate cancer, advanced kidney cancer, host energy balance Diana Hanna, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, United States of America gastrointestinal cancers Nader Hanna, Queen's University, Kingston, Ontario, Canada Thoracic Surgery, General Surgery, Foregut Surgery, Thoracic Malignancy, Health Services Research Ian Hirsch, Hospital Alvarez, Department of Oncology, Buenos Aires, Argentina General oncology Markus Hoffmann, Kiel University, Kiel, Germany Human Papillomavirus infection in head and neck cancer, sexual behavior and HPV infection, co- morbidity in head and neck cancer therapy, SLPI and Annexin A2 in HPV associated and not associated cancers Mustafa Ozan Horsanali, Bakircay University, , Turkey Urology, Andrology, Endourology, Female Urology Rashmi Maruti Hosalkar, MGM Dental College and Hospital, Mumbai, India Oral Oncology, Oral Potentially Malignant Disorders, Odontogenic Cyst and Tumours, Vesiculobullous Lesions Olivier Huillard, Université de Paris, Department of Medical Oncology, Paris, France Genitourinary cancers, Endocrine cancers, Medical Ethics Vamvakaris N. Ioannis, Sotiria General Hospital of Chest Diseases of Athens, Athens, Greece NSCLC, MSC in oncology Khushboo Irshad, All India Institute of Medical Sciences, New Delhi, India Cancer genetics, Glioma biology, Cell signaling, Tumor microenvironment, Inflammation Heba Ismail, University of California Riverside, Riverside, California, United States of America Masaoki Ito, Nomura Hospital, Hiroshima, Japan Thoracic surgery, Translational research/staging, Genomics, Surgery Rakesh Jalali, Apollo Proton Cancer Centre, Chennai, India Radiation Oncology Pradeep Jangampalli, Texas Tech University, Lubbock, Texas, United States of America Cancer Genomics, Bioinformatics, Drug Discovery, toxicology, Pharmacology, protein modeling, virtual screening, computational biology, Cancer Therapeutics Jose A Jeonimo, National Cancer Institute, Bethesda, Maryland, United States of America Gynecology Oncology, Cervical Cancer Jae-Hoon Ji, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America DNA damage response (DDR) and genomic instability, Epigenetic modifications in DDR, Ubiquitination and Parylation Mayumi M. Jijiwa, University of Hawai'i at Manoa John A Burns School of Medicine, , United States of America Cancer Biology, Human Pathology, Intracellular Signaling, Cell Proliferation, Invasion, Metastasis, Cancer Stem Cell, EMT, Neural Crest Cell, Mammalian Development, in vivo experiment Jun-O Jin, Yeungnam University, Gyeongsan, South Korea Cancer immunotherapy, Immunotherapy, Cancer vaccine, Immune check point inhibitor Chandan K Das, Post Graduate Institute of Medical Education and Research, Chandigarh, India Medical Oncology/Genitourinary Oncology/Gastrointestinal Oncology/ Gynecological Oncology Cameron K. Tebbi, Children Cancer Research Group Laboratories, Tampa, United States of America Pediatric Hematology Oncology Vefki Kadikoylu, Kent Health Group, Bone Marrow Transplantation Center, İzmir, Turkey Bone Marrow Transplantation, Hematological malignancies, Myeloproliferative neoplasms, Statins, Apheresis Sarada Preeta Kalainayakan, The University of Texas at Dallas, Richardson, Texas, United States of America Molecular biology, Cell biology, Cancer biology, Metabolism, Lung cancer Mohamed Gomaa Kamel, Minia University Faculty of Medicine, El Minia, Egypt Biomarkers, Diagnosis, Prognosis, Immunology, Clinical Research, Epidemiology, Prevention, Public Health, Biostatistics, Prediction, Diagnostic Accuracy, Regression, Survival Analysis, Systematic Review, Meta-analysis Kaori Kameyama, Showa University Northern Yokohama Hospital, Yokohama, Japan Thyroid and Parathyroid pathology Govind Babu Kanakasetty, St John's Medical College Hospital, Bangalore, India Medical oncology, NSCLC and HNSCC

AUTHOR INFORMATION PACK 1 Oct 2021 www.elsevier.com/locate/ctarc 6 Göktuğ Karabıyık, Koç University, İstanbul, Turkey Epigenetics, Cancer Biology (specifically Medulloblastoma), CRISPR/Cas9, Drug Resistance, Targeted Delivery Michalis Karamouzis, National and Kapodistrian University of Athens, Athens, Greece gastrointestinal cancers, breast cancers and aerodigestive carcinomas Megan Keniry, The University of Texas Rio Grande Valley - Edinburg Campus, Edinburg, Texas, United States of America PI3K Pathway, FOXO Transcription factors, GBM Hussein Khachfe, University of Pittsburgh Medical Center, Division of Gastrointestinal Surgical Oncology, Pittsburgh, United States of America Surgical Oncology, HPB Surgery, Robotic Surgery, Oncology, Pancreas Thomas Karsten Kilvaer, UiT The Arctic University of Norway, Tromsø, Norway Cancer biology, cancer biomarkers, artificial intelligence, sarcoma, NSCLC, radiotherapy Hong Sook Kim, Sungkyunkwan University, Jongno-gu, South Korea Cancer genomics, epigenetics, gene regulation, cancer immunotherapy Jongphil Kim, H. Lee Moffitt Cancer Center and Research Institute Department of Biostatistics and Bioinformatics, Tampa, Florida, United States of America Biostatistics, Design and Analysis of Phase I/II Clinical Trials, Multiple Comparisons, Time-To-Event Data Analysis, Concordance Analysis, BMT, Malignant Hematology, Imaging Data Analysis, Thoracic Oncology Richard Kim, Moffitt Cancer Center, Tampa, Florida, United States of America Gastrointestinal Cancers Vadim S Koshkin, UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California, United States of America Bladder cancer, Prostate cancer, Kidney cancer, Clinical trials Manigreeva Krishnatreya, Dr Bhubaneswar Borooah Cancer Institute, Guwahati, India Cancer registry, epidemiology, case-control studies, head and neck cancers Rohit Kumar, University of Louisville, Louisville, Kentucky, United States of America Thoracic oncology, Immunotherapy, Cancer related thrombosis Mary L. Alpaugh, Rowan University College of Science and Mathematics - School of Health Professions, Cancer biology and drug discovery Roberto La Rocca, University of Naples Federico II Department of Neuroscience and Reproductive Sciences and Dentistry, Napoli, Italy Urology, prostate cancer, kidney cancer, bladder cancer, penile cancer, urethral strictures. Matteo Lambertini, University of Genoa, Genova, Italy Breast cancer and survivorship, more specifically, breast cancer in young women, BRCA, fertility and pregnancy-related issues Denis Ulises Landaverde, Costa Rica University, San José, Costa Rica Breast Cancer, Medical Oncology Hun Ju Lee, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America Hodgkin lymphoma, Mantle cell lymphoma James Lee, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America Alessandro Leonetti, Amsterdam UMC VUMC Site, Amsterdam, Netherlands Lung cancer Daneng Li, City of Hope Comprehensive Cancer Center Duarte, Duarte, California, United States of America Hepatocellular carcinoma (HCC), Neuroendocrine tumors, Geriatric oncology Christopher Lieu, University of Colorado - Anschutz Medical Campus, Aurora, Colorado, United States of America Stephanie J. Lim, University of Hawai'i Cancer Center, Honolulu, Hawaii, United States of America Pediatric Oncology, Immunotherapy, CAR T cell therapy, Pediatric leukemia, Pediatric lymphoma Tiao Lin, Sun Yat-sen University First Affiliated Hospital, Guangzhou, China Osteoporosis, peri-prosthetic infection/bone loss, osteosarcoma, radiotherapy, chemotherapy Luca Giovanni Locatello, University Hospital Careggi, Firenze, Italy head and neck cancer, laryngeal cancer, salivary gland cancer, oral cavity cancer, otolaryngology-head and neck surgery, otorhinolaryngology Kristopher A. Lofgren, Gundersen Medical Foundation, La Crosse, Wisconsin, United States of America Breast Cancer, Cell Signaling (growth factors, kinases, nuclear receptors), Mouse Models of Cancer, Mammary Gland Development Celso Abdon Lopes de Mello, ACCamargo Cancer Center, Department of Medical Oncology, São Paulo, São Paulo, Brazil Medical oncology, colorectal carcinoma, sarcoma, treatment, prognosis, circulating tumor cell Jun Lu, Capital Medical University Youan Hospital, , China Hepatology and hepatocellular carcinoma, Cancer Biotherapy Ainhoa Madariaga, 12th of October University Hospital, Madrid, Spain Ovarian cancer, Endometrial cancer, Cervical cancer, Vulvar cancer, Vaginal cancer, Drug development

AUTHOR INFORMATION PACK 1 Oct 2021 www.elsevier.com/locate/ctarc 7 Amita Maheshwari, Tata Memorial Centre, Mumbai, India Gynecologic oncology, cervical cancer, ovarian cancer, uterine cancer Monica Malik, Nizam's Institute of Medical Sciences, Hyderabad, India Radiation Oncology, Palliative care and QOL Saima Shakil Malik, The University of Alabama at Birmingham, Birmingham, Alabama, United States of America Genomics, Proteomics, Post translational modifications, Epigenetics, DNA repair mechanisms, Drugs associated cytotoxicity, Gene–environment interaction, Oncology, Pathology and Epidemiology Murali K. Mamidi, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America Ankit Mangla, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States of America Soft-tissue Sarcoma, Melanoma, Bone Sarcoma Hitesh Mangukiya, Uppsala University Immunology Genetics and Pathology, Uppsala, Sweden Tumor microenvironment, Tumor target discovery, Molecular signaling, Cancer metastasis, Antibody discovery, Cancer therapy Antonino Maniaci, University of Catania Department of Surgical and Medical Sciences and Advanced Technologies "G.F. Ingrassia", Catania, Italy Head and Neck cancer, oral cancer, laryngeal cancer Yariswamy Manjunath, University of Missouri, Columbia, Missouri, United States of America Translational Oncology, Biomarkers in Cancer, Circualting Tumor Cells, non-small cell lung cancer Luca Marinelli, University of Rome La Sapienza, Roma, Italy Radiation oncology Goran Marjanović, University of Niš, Nis, Serbia Immuno hematology, Non hodgkin lymphomas, chronic lymphocitic leukemia Tomer Martin Mark, University of Colorado - Anschutz Medical Campus, Aurora, Colorado, United States of America Multiple Myeloma, Light Chain Amyloidosis, Autologous Stem Cell Transplant Benjamin L. Maughan, The University of Utah, Salt Lake City, Utah, United States of America genitourinary malignancies Bradley McGregor, Dana-Farber/Harvard Cancer Center, Boston, Massachusetts, United States of America Medical Oncology For Gu Malignancies, Focus On Non-Prostate Icro Meattini, University of Florence, Firenze, Italy Breast cancer, Clinical oncology, Radiation oncology Yoav Messinger, Children's Minnesota, Minneapolis, Minnesota, United States of America Childhood Leukemia, Lymphoma, Rare Tumors, DICER1 Syndrome Edoardo Migliori, Columbia University Irving Medical Center, New York, New York, United States of America Cancer immunology, CAR-T, cell therapy, viral carcinogenesis, and breast cancer Hamed Mirzaei, Kashan University of Medical Sciences, Institute for Basic Sciences, Kashan, Iran MicroRNA, LncRNA, circular RNA, Natural compunds, Cancer Kriti Mittal, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America Medical oncology, genitourinary oncology, renal cell carcinoma, urothelial carcinoma, prostate cancer, testicular cancer, adrenal cancer Mir Mohd Faheem, Council of Scientific & Industrial Research Indian Institute of Integrative Medicine, Srinagar, India Cancer cell signaling, EMT and metastasis, cancer drug discovery Hengameh Mojdeganlou, Urmia University of Medical Sciences, Urmia, Iran Cancer/pathology Mojtaba Mollaei, Tarbiat Modares University Department of Immunology, Tehran, Iran Cancer, Chemotherapy, Immunotherapy, Intracellular signaling, Apoptosis, Chemoresistance, The role of MicroRNAs and Long non-coding RNAs in cancer development Floriana Morgillo, University of Campania Luigi Vanvitelli, Napoli, Italy Thoracic Head and Neck Pavlos Msaouel, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America Renal cell carcinoma, Renal medullary carcinoma, SMARCB1 loss, Non-clear cell renal cell carcinoma Nupur Mukherjee, National Institute for Research in Reproductive Health Department of Innate Immunity, Mumbai, India Cancer Immunology, Molecular biology of Breast cancer, Translational Oncology, molecular therapeutics of cancer, Immunotherapy, transcription profiles of oncogenes, TSGs and pattern recognition receptors in cancer Fahad Mukhtar, University of South Florida, Tampa, Florida, United States of America Cancer epidemiology, lymphoma, multiple primary malignancies, cancer disparities , , Layth Mula-Hussain, University of Ottawa Divisions of Radiation Oncology, Ottawa, Ontario, Canada Radiation oncology Masaki Nagaya, St. Marianna University School of Medicine, Department of Immunology, Kawasaki, Japan

AUTHOR INFORMATION PACK 1 Oct 2021 www.elsevier.com/locate/ctarc 8 GI cancer Madhumathy Nair, St John's National Academy of Health Sciences Division of Molecular Medicine, Bengaluru, India Breast cancer biology, MicroRNAs, Tumor microenvironment, Metastasis, Chemoresistance Geeta S. Narayanan, Vydehi Institute of Medical Sciences and Research Centre, Bangalore, India Radiation oncology, Comparison of HPV genotype and response to chemo radiation in cervical cancer, Evaluation of telomerase as a tumor marker in head and neck cancer, Functional MRI imaging in cervical cancer brachytherapy, MRI adapted brachytherapy in cervical cancer, Evaluating the role of Neo adjuvant chemo therapy in various cancer sites Azadeh Nasrazadani, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States of America breast cancer Loretta Nastoupil, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America Lymphoma/Myeloma Arash Navran, Antoni van Leeuwenhoek Netherlands Cancer Institute, Amsterdam, Netherlands Head and neck cancer, radiotherapy, chemoradiation, combined treatment, HNSCC, treatment toxicity, outcome, margin reduction, VMAT Vahideh Nazari, Hamadan University of Medical Sciences, Hamedan, Iran Medical physic, Dosimetry, Medical image processing, Adaptive radiotherapy, Patient-specific radiation treatment quality assurance, Radiation protection Aziz Nazha, Cleveland Clinic, Cleveland, Ohio, United States of America leukemia Ntokozo Ndlovu, University of Zimbabwe, Harare, Zimbabwe Radiation/Clinical Oncology, Cancer, Cervical Cancer, Breast Cancer, HIV related Cancers, Prostate Cancer, Cancer Epidemiology Hovav Nechushtan, Hadassah Medical Center, Jerusalem, Israel Signal Transduction, Lung Cancer, Personalized Medicine (Oncology) Hema Negi, Shanghai Jiao Tong University, Shanghai, China Clinical Oncology, Animal tumor models , molecular oncology Erika A. Newman, C S Mott Children's Hospital, Department of Pediatric Surgery, Ann Arbor, Michigan, United States of America Neuroblastoma and pediatric tumor biology, DNA repair, cancer xenograft models Bikesh Kumar Nirala, Baylor College of Medicine, Houston, Texas, United States of America Tumor microenvironment, Immunology, Tumor immunotherapy, Paediatric tumor, Diabetes, Glycation biology Gengming Niu, Fifth People's Hospital of Shanghai Fudan University, Shanghai, China Gastrointestinal cancers Xiaomin Niu, Shanghai Jiao Tong University Affiliated Chest Hospital, Shanghai, China Thoracic cancer Scott S. Oh, University of California Los Angeles, Los Angeles, California, United States of America pulmonary medicine Rodrigo Otavio de Castro Araujo, National Institute for Cancer, Rio de Janeiro, Brazil Surgical Oncology, Rectal Cancer, Translational research Mustafa Özgüroğlu, Istanbul University, Fatih, Turkey Internal medicine, medical oncology, GU and Lung cancers Martin P. Barr, Saint James's Hospital, Dublin, Ireland Non-small cell lung cancer (NSCLC), VEGF signaling, microRNAs, biomarkers, drug repurposing, liquid biopsy, treatment resistance, cancer stem cell biology, translational cancer research Harish Padh, Sardar Patel University, Vallabh Vidhyanagar, India Genetics, cancer and cancer treatment, Cancer Biology, Pharmacogenetics Sumanta K. Pal, City of Hope Comprehensive Cancer Center Duarte, Duarte, California, United States of America Urology And Urologic Oncology, Kidney Cancer, Bladder Cancer, Prostate Cancer, , Laura Paleari, ALiSa Regional Health System of Liguria, Genova, Italy Cancer prevention, molecular biology, drug repurposing, health technology assessment, pharmacoeconomics Parijat Pandey, Baba Mastnath University, Bohar, India Nanotechnology, Oncology and Formulation Development Alex Papachristodoulou, Columbia University Irving Medical Center, New York, New York, United States of America Prostate Cancer, Glioblastoma, Mitochondria and Metabolism, , Mamta Parikh, UC Davis Comprehensive Cancer Center, Sacramento, California, United States of America Genitourinary Oncology, Early Developmental Therapeutics

AUTHOR INFORMATION PACK 1 Oct 2021 www.elsevier.com/locate/ctarc 9 Sunil Pasricha, Rajiv Gandhi Cancer Institute and Research Centre, New Delhi, India Oncopathology Sofia S. Pereira, University of Porto, Porto, Portugal Adrenocortical tumors, obesity, endocrine tumors Iacopo Petrini, University of Pisa Department of Translational Research and New Technologies in Medicine and Surgery, Pisa, Italy Thoracic oncology and genomic sequencing Noam Falbel Pondé, ACCamargo Cancer Center, SAO PAULO, Brazil Breast cancer, Geriatric oncology Elizabeta Popa, Weill Cornell Medicine Joan and Sanford I Weill Department of Medicine, New York, New York, United States of America neuroendocrine cancer, sarcoma, pancreatic cancer, rare tumors, colon cancer, liver cancer, biliary cancer, gastric cancer, esophageal cancer, head neck cancer Sophie Postel-Vinay, Gustave Roussy, Villejuif, France lung cancer Dinesh Pradhan, Aurora Diagnostics, Palm Beach Gardens, Florida, United States of America Melanoma, Cancer genetics and epigenetics, Vulvar cancer, Cutaneous lymphoma Vít Procházka, Palacky University Olomouc Faculty of Medicine and Dentistry, , Czechia Lymphoma, biomarkers, imaging (PET), prognosis Juan Qian, Affiliated Hospital of Nantong University, , China Hematology Weiqiang Qiao, Henan University of Science and Technology Affiliated First Hospital, Luoyang, China Evidence-based medicine, Breast cancer, Meta-analysis Giovanni Raffa, University of Messina Department of Neurosurgery, Messina, Italy Neuro-Oncology, Brain Tumors, Gliomas, Meningiomas, Brain metastases Shyam Rao, University of California Davis School of Medicine, Sacramento, California, United States of America Elie Rassy, Gustave Roussy, Villejuif, France Precision oncology, early-stage cancer detection, cancer of unknown primary, urogenital cancers María Cecilia Ricart, University of Buenos Aires, Buenos Aires, Argentina Clinical Veterinary, Gastroenterology, Endoscopy, Biochemistry, Reproduction science Manglio Rizzo, Austral University Cancer Immunobiology Laboratory, Buenos Aires, Argentina Lung cancer, immunotherapy, real world data, tumor microenvironment, extracellular matrix, hyalurnic acid, clinical trial Graziana Ronzino, Hospital Vito Fazzi, Lecce, Italy Gynecologic oncology, Head and neck cancer, Familial cancer syndromes, Familial breast/ovarian cancer Giovanni Rosti, Foundation IRCCS Polyclinic San Matteo, Pavia, Italy Testicular cancer, High dose chemotherapy, Supportive therapy Anwaar Saeed, The University of Kansas Cancer Center Drug Discovery, Delivery and Experimental Therapeutics, Kansas City, Kansas, United States of America Immunotherapy and Immune modulation in Gastrointestinal malignancies, Gastric and Esophageal Cancer,Colorectal cancer and Hepatocellular carcinoma Kamal Sahu, University of Utah Health Huntsman Cancer Institute, Salt Lake City, Utah, United States of America Leukaemia, Lymphoma, Myeloma, Benign hematology, Sickle cell disease, Thalassemia, Methemoglobinemia, Myeloid sarcoma Nasreena Sajjad, University of Kashmir, Srinagar, India Antioxidants, Antioxidant Activity, Reactive Oxygen Species, Phytochemicals, Natural Product Chemistry, Extraction, Chromatography, Bioactivity, Biomarkers, Food Chemistry Ikuko Sakamto, Yamanashi Prefecture Central Hospital, Kofu, Japan Gynecologic oncology, endometrial cancer, ovarian cancer, cervical cancer Maribel Salas, Daiichi Sankyo Inc, Basking Ridge, New Jersey, United States of America Internal medicine, pharmacoepidemiology, pharmacovigilance, patient safety Alejandro Sanchez, University of Utah Health Huntsman Cancer Institute, Salt Lake City, Utah, United States of America Genitourinary Surgical Oncology Muzaffer Sanci, Tepecik Training and Research Hospital Clinics, Konak, Turkey Rare Genital Tumours Alberto Sandri, San Luigi Gonzaga University Hospital, Thoracic Surgery Unit, Orbassano, Italy Thoracic oncology, minimally invasive surgery (uniportal VATS), technology applied to thoracic surgery, lung cancer, lung lobectomy, lung segmentectomy, NSCLC, lung function test, mesothelioma, neuroendocrine tumours of the lung and thymus Jacob Sands, Dana-Farber/Harvard Cancer Center, Boston, Massachusetts, United States of America Small Cell Lung Cancer, Non-Small Cell Lung Cancer, Immunotherapy

AUTHOR INFORMATION PACK 1 Oct 2021 www.elsevier.com/locate/ctarc 10 Daniele Santini, Campus Bio-Medico University Hospital, Roma, Italy GU cancers, GI Cancers, Supportive Therapy, Bone Metastases Julien Sarkis, Saint Joseph University, Beirut, Lebanon Urology (Genito-urinary tumors- prostate cancer, Bladder cancer, Kidney cancer, Cancer biomarkers, Immunotherapy) Yasushi Sasaki, Sapporo Medical University, Sapporo, Japan Molecular mechanisms of human carcinogenesis, Functional analysis of p53 family, Cancer genetics (Oral cancer, Gastrointestinal cancer, Pancreatic cancer) Nicolas Sayegh, University of Utah Health Huntsman Cancer Institute, Salt Lake City, Utah, United States of America Genitourinary Oncology Benedict Seo, University of Otago Department of Oral Diagnostic and Surgical Sciences, Dunedin, New Zealand Oral and maxillofacial pathology, histopathology, oral squamous cell carcinoma, unfolded protein response Vinit Shanbhag, University of Missouri, Columbia, Missouri, United States of America Biochemistry, Biology of cancer, Drug discovery, and development, Molecular biology and signaling Marisa Shiina, University of California San Francisco, San Francisco, California, United States of America Drug resistance, epigenetic, cancer stem cells, neuroendocrine differentiation, biomarkers, cell signaling pathways, small molecule inhibitors Nicholas Short, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America Leukemia Richa Singhania, Weill Cornell Medicine, New York, New York, United States of America Molecular Neuro-Oncology, Stem Cell Biology Charalampos Siotos, Rush University Medical Center, Chicago, Illinois, United States of America Breast cancer, mastectomy, breast reconstruction, oncoplastic surgery Salvatore Siracusano, University of Aquila, L'Aquila, Italy Bladder and prostate cancer Heloisa P. Soares, University of Utah Health Huntsman Cancer Institute, Salt Lake City, Utah, United States of America Neuroendocrine Tumors And Gastrointestinal Cancers, Clinical Trials Carmino Antonio de Souza, State University of Campinas, Campinas, São Paulo, Brazil Oncohematology and bone marrow transplantation, CML and malignant lymphomas Aris Spathis, General University Hospital Attikon, Athens, Greece Molecular and cellular techniques with expertise in flow cytometry for diagnosis, typing, monitoring and treatment of malignancies Carlo Sposito, Foundation IRCCS National Cancer Institute, Milan, Italy Hepatocellular carcinoma, Cholangiocarcinoma, Liver transplantation, Radioembolization, Chemoembolization, Liver surgery, Mini-invasive surgery, Laparoscopic surgery, Liver tumors, Pancreatic cancer, Gastric cancer, Esophago-gastric surgery Czesław Stankiewicz, Medical University of Gdansk, Gdansk, Poland Otorhinolaryngology, head and neck cancer Michiel Strijbos, KU Leuven University Hospitals Leuven, Leuven, Belgium genitourinary malignancies Tan Su-Ming, Changi General Hospital, Singapore, Singapore Breast Cancer Elgar Susanne Quabius, Kiel University, Kiel, Germany Argiris Symeonidis, University of Patras, Patras, Greece Gaucher disease, hematology, myelodysplastic syndromes, multiple myeloma, chronic myeloproliferative neoplasms, anemia, erythropoiesis, lymphoproliferative disorders, targeted treatments in hematology Hiroyuki Takei, Nippon Medical School, Bunkyo-Ku, Japan Metastasis,Tumor Angiogenesis, Oncology Yuichi Tambo, Kanazawa University Hospital, Kanazawa, Japan Lung Cancer, NSCLC, SCLC, Immuno Oncology, Targeted Therapy, Translational Research, Clinical Trial Daniel Tan, National Cancer Centre Singapore, Singapore, Singapore Thoracic, head and neck malignancies and drug development Ozgur Tanriverdi, Muğla Sıtkı Koçman University, Muğla, Turkey Medical Oncology, Palliative Care, Psychooncology, Molecular Biology and Genetics, Gerontology Nikolaos Thomakos, National and Kapodistrian University of Athens, Athens, Greece Perioperative care in Gyn/Oncology, Fertility sparing management in Gyn cancer Elizabeth Thomas, University of Maryland School of Medicine, Baltimore, Maryland, United States of America Oncogenic signaling, tumor progression & metastasis and cancer therapeutics Anil Tombak, Mersin University, Mersin, Turkey

AUTHOR INFORMATION PACK 1 Oct 2021 www.elsevier.com/locate/ctarc 11 CLL, multple myeloma, lymphoma Naoomi Tominaga, Yamaguchi University, Yamaguchi, Japan Breast Cancer, Extracellular vesicles, Pathology Giuseppe Troiano, University of Foggia, Foggia, Italy Evidence-based Medicine, Meta-analysis, Prognostic Biomarker, oral squamous cell carcinoma Siddhartha Tyagi, Baylor College of Medicine Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Houston, Texas, United States of America Breast cancer, MYC, Splicing, Preclinical trials, Xenografts, Development of GEMM and PDX models, Molecular biology, Development and design new vectors, CRISPER, Development of in vivo screen technologies, Q PCR, , Jeewan Ram Vishnoi, All India Institute of Medical Sciences, New Delhi, India Surgical Oncology, Gastrointestinal Cancer, Head, and Neck Cancer, Breast Cancer, Cancer Epidemiology, Cancer Biomarkers, Translational Oncology Mariza Vorster, University of Pretoria, Pretoria, South Africa Nuclear medicine, theranostic, Ga-68-based PET, PET/CT, molecular imaging, targeted radionuclide therapy Che-Wei Wu, Kaohsiung Medical University College of Medicine, , Taiwan Head and Neck Cancer, Thyroid Cancer, Oral Cancer, Thyroid and Parathyroid Surgery, Intraoperative Neural Monitoring Li Xie, Shanghai Jiao Tong University School of Medicine, Shanghai, China Biostatistics, Epidemiology, Clinical trials, Cancer Peng Xie, Shandong Cancer Hospital and Institute, Jinan, China Gynecologic Oncology, Radiation Oncology Fevzi Yalniz, Legend Biotech, Piscataway, New Jersey, United States of America Hematological malignancies including myeloid malignancies such as myelodysplastic syndromes and acute myeloid leukemias, lymphoid malignancies including chronic and acute leukemias as well as lymphomas, Adoptive cellular therapies including CAR-T, Stem cell transplantation Yongyong Yang, Northwestern University, Evanston, Illinois, United States of America Prostate cancer, Molecular Biology, Long non-coding RNA (lncRNA), MicroRNA, Non-histone protein methylation modification, and Epigenetics Jun Yin, Mayo Clinic, Scottsdale, Arizona, United States of America Clinical Trial Designs, Biostatistics, Cancer Prognosis and Prediction, Biomarker Validation, Epidemiology Hongwei H. Zhang, The Affiliated Hospital of Southwest Medical University, Luzhou, China Blood Platelets and Neoplasms Tian Zhang, Duke Cancer Institute, Durham, North Carolina, United States of America Genitourinary Malignancies; Urothelial Cancer; Renal Cell Carcinoma; Prostate Cancer Dachen Zhou, The Second Hospital of Anhui Medical University, Anhui, China Hepatocarcinoma, mRNA translation, Liver cirrhosis, Cancer treatment Viola Zhu, University of California Irvine, Irvine, California, United States of America Lung Cancer Stefan Zimmermann, University of Lausanne, Lausanne, Switzerland International Advisory Board Utkarsh Acharya, Dana-Farber/Harvard Cancer Center, Boston, Massachusetts, United States of America Adoptive cell transfer, Cellular immunotherapy, Chimeric antigen receptor (CAR) T-cell therapy, Hematologic malignancies Nikolaos Andreatos, Cleveland Clinic, Cleveland, Ohio, United States of America Gastrointestinal oncology, Biomarker validation, Prognostic modelling Arnab Basu, The University of Alabama at Birmingham O'Neal Comprehensive Cancer Center, Birmingham, Alabama, United States of America Genitourinary malignancies Melissa Bersanelli, University Hospital of Parma, Parma, Italy Renal cell carcinoma, Urothelial cancer, Melanoma Gulzar Ahmad Bhat, University of Kashmir, Srinagar, India Cancer Biology & Cancer Epidemiology Federica Biello, University Hospital Maggiore della Carità, Novara, Italy Thoracic oncology, Lung cancer Luca Boldrini, University Hospital Agostino Gemelli Department of Diagnostic Imaging, Oncological Radiotherapy and Hematology, Roma, Italy Radiotherapy, MRI guided radiotherapy, Artificial Intelligence, Hybrid imaging, Radiomics Simona Borstnar, Institute of Oncology Ljubljana, Ljubljana, Slovenia Breast cancer

AUTHOR INFORMATION PACK 1 Oct 2021 www.elsevier.com/locate/ctarc 12 Terrence J Bradley, Sylvester Comprehensive Cancer Center, Miami, Florida, United States of America Malignant Hematology, MDS, AML, ALL, MPN, CML Doris R. Brown, Wake Forest Baptist Health, Winston-Salem, North Carolina, United States of America Radiation oncology James Brown, University of Limerick, Limerick, Ireland Breast cancer, Biomarker identification, Genome stability Liubo Chen, Zhejiang University School of Medicine Second Affiliated Hospital, Hangzhou, China Management and prevention of gastrointestinal cancer, Molecular mechanisms of colorectal cancer Michael Co, Queen Mary Hospital, Hong Kong, Hong Kong Breast Surgical Oncology, General Surgery Savita Dandapani, City of Hope Comprehensive Cancer Center Duarte, Duarte, California, United States of America Radiation oncology, Radiation Treatment for Lymphoma, Genitourinary and Brain Cancers, Radioimmunotherapy, Stereotactic Radiosurgery Melissa Boneta Davis, Weill Cornell Medicine, New York, New York, United States of America Molecular genetics, genomics and systems biology, breast cancer Umut Disel, Acibadem Hospitals Group Department of Medical Oncology, Adana, Turkey Clinical oncology, Precision medicine trials, Genome sequencing (exome-Whole), Immunooncology and exceptional responders-case studies and Molecularly targeted therapies. Greg Durm, Indiana University Melvin and Bren Simon Cancer Center, Indianapolis, Indiana, United States of America Head and neck- and lung cancer Inas El-Attar, National Cancer Institute Cairo University, Cairo, Egypt Biostatistics Oliver Eng, The University of Chicago, Chicago, Illinois, United States of America Surgical Oncology, Gastrointestinal Malignancies, Peritoneal Surface Malignancies, Cytoreductive Surgery and HIPEC Aaron T. Gerds, Cleveland Clinic Taussig Cancer Center, Cleveland, Ohio, United States of America Hematologic malignancies Georgia L Gomatou, National and Kapodistrian University of Athens, Athens, Greece Medical Oncology, Thoracic Oncology, Cancer Biology Teresa Alonso Gordoa, Ramón y Cajal Institute for Health Research, Madrid, Spain Prostate cancer, Bladder cancer, Kidney cancer, Testicular germ cell tumor, Thyroid tumor, Neuroendocrine tumor Sanjeev Gupta, National University of Ireland Galway, Galway, Ireland Unfolded Protein response, Endocrine resistance, microRNAs, cell death, breast cancer, non-coding RNAs, Endoplasmic reticulum stress Samer Al Hadidi, Baylor College of Medicine, Houston, Texas, United States of America Malignant hematology, lymphoma, myeloma and leukemia Rohit Jain, Moffitt Cancer Center Department of Genitourinary Oncology, Tampa, Florida, United States of America Genitourinary Oncology, Bladder Cancer, Kidney (Renal Cell) Cancer, Prostate Cancer Hüseyin Kadioǧlu, BHT Clinic Istanbul Tema Hospital, İstanbul, Turkey General Surgery Catherine Lai, Georgetown University Medical Center Lombardi Comprehensive Cancer Center Dept. of Oncology, Washington, District of Columbia, United States of America AML, MDS, ALL, CML Makoto Maemondo, Iwate Medical University Department of Internal Medicine Division of Respiratory Medicine, Iwate, Japan Translational oncology, Lung cancer research Francesco Mannavola, University of Bari, Bari, Italy Liquid biopsy, Extracellular vesicles, Colorectal cancer Rutika Mehta, Moffitt Cancer Center, Tampa, Florida, United States of America GI Medical Oncology Luca Moscetti, University Hospital Modena, Modena, Italy Breast Cancer Eli Muchtar, Mayo Clinic Rochester, Rochester, Minnesota, United States of America Multiple myeloma, AL amyloidosis, MGUS, Waldenström macroglobulinemia, CLL, hairy cell Leukemia, LGL Leukemia, general Hematology, stem cell transplantation Pashna N. Munshi, MedStar Georgetown University Hospital, Washington, District of Columbia, United States of America Stem Cell Transplant and Cellular Immunotherapy (autologous, allogeneic transplant, CAR T-cell therapies)

AUTHOR INFORMATION PACK 1 Oct 2021 www.elsevier.com/locate/ctarc 13 Ranjit Nair, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America Lymphoma/ Myeloma Marcus S. Noel, Georgetown Lombardi Comprehensive Cancer Center, Washington, District of Columbia, United States of America Gastrointestinal oncology Amit Kumar Pandey, Amity University Amity Institute of Biotechnology, Noida, India Non-Coding RNA, Cancer, Molecular Biology, Cell signalling Jason R. Pitarresi, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America pancreatic cancer, tumor microenvironment, mouse modeling, metastasis, cellular plasticity, epithelial-to-mesenchymal transition (EMT) Kam Sheung Poon, Queen Elizabeth Hospital, Hong Kong, Hong Kong General medicine, perioperative cancer medicine, cancer pain management Jun Ren, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, United States of America Tumor microenvironment, Cancer immunotherapy, CAR T therapy, Vascular biology Cristina Pinto Ribeiro Xavier, University of Porto Institute for Research and Innovation in Health Sciences, Porto, Portugal Cellular and molecular biology, Cancer biology, Molecular carcinogenesis, Cell signalling, Cell death and autophagy, Cell cycle regulation, Drug and target discovery and molecular pharmacology Mersedeh Rohanizadegan, Boston Children's Hospital, Boston, Massachusetts, United States of America Sacha Rothschild, University Hospital Basel, Basel, Switzerland Thoracic oncology and Head and neck tumors Mohammad Sayyadi, Arak University of Medical Sciences, Arak, Iran Cancer biology, Leukemic, Cell signalling, Drug efficiency in cancer Daniele Scartoni, Proton Therapy Center Trento, Trento, Italy Radiotherapy, proton therapy, brain tumors, toracic tumors, GI tumors Joel E. Segel, The Pennsylvania State University, University Park, United States of America Cancer health economics, Breast cancer and Genitourinary cancers Alka Sehgal, Government Medical College and Hospital, Chandigarh, India Obstetrics and Gynecology Zhiyong Shen, Southern Medical University Nanfang Hospital, , China The molecular mechanism of occurrence and development of colorectal cancer, Cancer metabolism, Transcriptional regulation, immune microenviroment) Minimally invasive treatment for gastrointestinal diseases, especially laparoscopic surgery for colorectal cancers. Mustaqeem A. Siddiqui, Mayo Clinic Rochester, Rochester, Minnesota, United States of America Hematologic malignancies Raphael Eric Steiner, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America Lymphoma Umang Swami, University of Utah Health Huntsman Cancer Institute, Salt Lake City, Utah, United States of America Medical Oncology -- Genitourinary cancers (kidney, bladder, prostate and testicular cancers), melanoma Marco Tagliamento, Research Hospital San Martino, Genova, Italy Lung cancer Caitlin Taylor, Emory University School of Medicine, Atlanta, Georgia, United States of America Breast cancer Monica Terenziani, Foundation IRCCS National Cancer Institute, Milan, Italy Cancer survivorship, Pediatric germ cell tumors, Oncofertility and Pediatric Hodgkin Lymphoma Suen To-ki Dacita, The University of Hong Kong, Hong Kong, China Breast Surgery Abhishek Tripathi, The University of Oklahoma Stephenson Cancer Center, Oklahoma City, Oklahoma, United States of America Clinical trials, genitourinary oncology, kidney, bladder and prostate cancer Pankit Vachhani, The University of Alabama at Birmingham O'Neal Comprehensive Cancer Center, Birmingham, Alabama, United States of America Leukemia Anderson Vulczak, University of Sao Paulo, São Paulo, Brazil Tumor metabolism, Physical Exercise - Oncology, Breast Cancer Mira Sudam Wagh, Regional Cancer Centre Thiruvananthapuram, Thiruvananthapuram, India Upper Gastrointestinal malignancies, Lower Gastrointestinal malignancies, Hepaobiliary and Pancreatic cancers. Alexander TH Wu, Taipei Medical University, Taipei, Taiwan

AUTHOR INFORMATION PACK 1 Oct 2021 www.elsevier.com/locate/ctarc 14 Cancer biology, Tumor microenvironment, Cell and immunotherapies for cancer and New drug development

AUTHOR INFORMATION PACK 1 Oct 2021 www.elsevier.com/locate/ctarc 15 GUIDE FOR AUTHORS

. Your Paper Your Way We now differentiate between the requirements for new and revised submissions. You may choose to submit your manuscript as a single Word or PDF file to be used in the refereeing process. Only when your paper is at the revision stage, will you be requested to put your paper in to a 'correct format' for acceptance and provide the items required for the publication of your article. To find out more, please visit the Preparation section below. INTRODUCTION Cancer Treatment and Research Communications(CTARC) is an international peer-reviewed journal dedicated to publishing comprehensive basic, translational, and clinical oncology research. CTARC considers articles on detection, diagnosis, prevention, policy, and treatment of cancer, and provides a global forum for the nurturing and development of future generations of oncology scientists. CTARC publishes comprehensive reviews and original studies describing various aspects of basic through clinical research of all tumor types. The journal also accepts clinical studies in oncology, with an emphasis on prospective early phase clinical trials.

Specific areas of interest include basic, translational, and clinical research and mechanistic approaches; cancer biology; molecular carcinogenesis; genetics and genomics; stem cell and developmental biology; immunology; molecular and cellular oncology; systems biology; drug sensitivity and resistance; gene and antisense therapy; pathology, markers, and prognostic indicators; chemoprevention strategies; multimodality therapy; cancer policy; and integration of various approaches. Our mission is to be the premier source of relevant information through promoting excellence in research and facilitating the timely translation of that science to health care and clinical practice. Types of Articles Cancer Treatment and Research Communications publishes material in the form of original articles, review articles, opinions, short communications such as spotlights, previews and perspectives, case reports and letters to the editor. Original Research Article Original, full-length research articles which have not been published previously, except in a preliminary form, may be submitted. Original Studies present results of original basic and translational research.

Mechanics: Original research articles should include a structured abstract and should be divided into sections (Introduction, Materials and Methods, Results and Discussion). Original research articles have a limit of 4,500 words and no more than 50 references. Authors are asked to limit the number of figures and/or tables to 6. Reviews and Opinions Review Article

Review articles offer a balanced account of newly emerging or rapidly progressing fields and provide a guide to the most relevant recent literature and prospects for future research.

They should briefly set the background and then concentrate on setting recent findings in context. It is crucial that they should give a balanced view of developments, even in fields that are controversial, and authors must never concentrate unduly on their own research. Although Reviews do allow room for some speculation and debate, it should be made clear where the authors' own opinions are being presented.

References selected for publication should be chosen for their importance, ease of access, and for the "further reading" opportunities they provide; citations to papers published in non-peer-reviewed supplements are discouraged.

Mechanics: Reviews articles should contain a short abstract stating the goal of the review, an introduction, discussion, and conclusion. Reviews have a limit of 4,500 words and no more than 80 references. Authors are asked to limit the number of figures and/or tables to 6. Reviews should have no more than 5 authors without prior agreement of the editors.

AUTHOR INFORMATION PACK 1 Oct 2021 www.elsevier.com/locate/ctarc 16 Opinion article

Opinions may reflect an individual perception, involvement, or contribution to oncology, and should be prepared in a similar way to a Review. Opinions should present a personal and original perspective on an important research-related topic of interest to the cancer research community, rather than a balanced review of this topic.

The aim should be to stimulate debate or new research, cover controversial topics, or provide a new framework for, or interpretation of, an old problem or current issue, or speculate on the implications of some recent research. Although Opinion articles can be more 'forward looking' than Reviews, please avoid being overly speculative. Please note that articles that outline recent advances in a field rather than give a strong opinion on them are not suitable for this section of the journal; neither are hypotheses without any published support.

Mechanics: Opinion articles have a limit of 2,500 words and no more than 60 references. Authors are asked to limit the number of figures and/or tables to 6. Opinions should have no more than 3 authors without prior approval from the editors. Opinions should include an abstract. Short Communications Spotlights

Spotlights are short articles intended to provide a quick update on one or two recent research articles published in other journals that signify a major advancement in a specific field of Cancer. Spotlights should give additional insight on the topic, highlighting broader implications for the field that have not already been provided by the original paper(s). Although subjective, Spotlight articles should not be used to dwell excessively on the author's own research, to introduce new (unpublished) data, or to excessively criticize the work of others, except where criticism is constructive.

Please send a pre-submission inquiry to the Journal Inbox: [email protected]

Mechanics: Spotlights have a limit of 1,500 words and no more than 10 references. Authors are asked to limit the number of figures and/or tables to 2. Spotlights should include an abstract.

Commentaries

Commentaries are short articles that highlight one or several research papers published in a recent issue of the Journal, placing the results in context for the journal's broad readership. Commentaries are commissioned by the editors to accompany new papers in Cancer Treatment and Research Communications . Unsolicited contributions are not considered.

Mechanics: Commentaries have a limit of 1,500 words and no more than 10 references. Authors are asked to limit the number of figures and/or tables to 2. Commentaries should include an abstract.

Perspectives

Perspectives are short pieces that aim to highlight for a very broad audience a significant recent development in the field or to raise awareness about a topic of general interest. Possible topics can include future outlook essays that serve to introduce or encourage research in a new field, reflections and new insights on long-standing questions and debates, and general analyses of common scientific practices or tools used in a field.

Perspectives should not include unpublished data, simulations, or meta-analyses. Although subjective, a perspective should not be used to dwell excessively on the author's own research or to excessively criticize the research of others, except where criticism is constructive. The introduction of hypothesis and models is encouraged, and the articles should be written with a very personal perspective, but it is important to mention other viewpoints where they exist to place the work discussed in a context for the nonspecialist reader.

AUTHOR INFORMATION PACK 1 Oct 2021 www.elsevier.com/locate/ctarc 17 Please send a pre-submission inquiry to the Journal Inbox: [email protected]: Perspectives have a limit of 1,200 words and no more than 10 references. Authors are asked to limit the number of figures and/or tables to 2. Perspectives should have no more than 3 authors without prior approval from the editors. Perspectives should include an abstract. Letters to the Editors Letters to the Editors which comment directly on work that has previously been published in the Journal will be considered. The author of the paper on which the Letter is commenting will be contacted and invited to respond.

Mechanics: Letters have a limit of 1,000 words and no more than 10 references. Authors are asked to limit the number of figures and/or tables to 1. Letters should not include an abstract or have more than 3 authors without prior approval from the editors. Editorials Editorials serve as the voice of Cancer Treatment and Research Communications and are written by the Journal's Editors and Guest Editors. Case Reports Case reports should describe a single case or a small series of cases. They should present significant new insights on cases with a noteworthy course, striving to inform clinical cancer research and care. Case reports should draw attention to important clinical situations, unusual clinical phenomena, new treatment protocols, or new complications in a single patient or in a small number of patients.

Mechanics: Case reports should be arranged according to the following sections: Title Page, Unstructured Abstract, Introduction, Cases and Methods, Discussion and Conclusion. Case reports should contain up to 2,500 words, up to 6 figures and/or tables and up to 15 references. Prior Publication The submitted material must not be published nor submitted elsewhere, except in abstract form. Submission Checklist

You can use this list to carry out a final check of your submission before you send it to the journal for review. Please check the relevant section in this Guide for Authors for more details.

Ensure that the following items are present:

One author has been designated as the corresponding author with contact details: • E-mail address • Full postal address

All necessary files have been uploaded: Manuscript: • Include keywords • All figures (include relevant captions) • All tables (including titles, description, footnotes) • Ensure all figure and table citations in the text match the files provided • Indicate clearly if color should be used for any figures in print Graphical Abstracts / Highlights files (where applicable) Supplemental files (where applicable)

Further considerations • Manuscript has been 'spell checked' and 'grammar checked' • All references mentioned in the Reference List are cited in the text, and vice versa • Permission has been obtained for use of copyrighted material from other sources (including the Internet) • Relevant declarations of interest have been made • Journal policies detailed in this guide have been reviewed • Minimum of 3 suggested reviewers, with institutional affiliations, and email addresses

For further information, visit our Support Center.

AUTHOR INFORMATION PACK 1 Oct 2021 www.elsevier.com/locate/ctarc 18 BEFORE YOU BEGIN Ethics in publishing Please see our information on Ethics in publishing. Studies in humans and animals If the work involves the use of human subjects, the author should ensure that the work described has been carried out in accordance with The Code of Ethics of the World Medical Association (Declaration of Helsinki) for experiments involving humans. The manuscript should be in line with the Recommendations for the Conduct, Reporting, Editing and Publication of Scholarly Work in Medical Journals and aim for the inclusion of representative human populations (sex, age and ethnicity) as per those recommendations. The terms sex and gender should be used correctly.

Authors should include a statement in the manuscript that informed consent was obtained for experimentation with human subjects. The privacy rights of human subjects must always be observed.

All animal experiments should comply with the ARRIVE guidelines and should be carried out in accordance with the U.K. Animals (Scientific Procedures) Act, 1986 and associated guidelines, EU Directive 2010/63/EU for animal experiments, or the National Institutes of Health guide for the care and use of Laboratory animals (NIH Publications No. 8023, revised 1978) and the authors should clearly indicate in the manuscript that such guidelines have been followed. The sex of animals must be indicated, and where appropriate, the influence (or association) of sex on the results of the study. Informed consent and patient details Studies on patients or volunteers require ethics committee approval and informed consent, which should be documented in the paper. Appropriate consents, permissions and releases must be obtained where an author wishes to include case details or other personal information or images of patients and any other individuals in an Elsevier publication. Written consents must be retained by the author but copies should not be provided to the journal. Only if specifically requested by the journal in exceptional circumstances (for example if a legal issue arises) the author must provide copies of the consents or evidence that such consents have been obtained. For more information, please review the Elsevier Policy on the Use of Images or Personal Information of Patients or other Individuals. Unless you have written permission from the patient (or, where applicable, the next of kin), the personal details of any patient included in any part of the article and in any supplementary materials (including all illustrations and videos) must be removed before submission. Declaration of competing interest All authors must disclose any financial and personal relationships with other people or organizations that could inappropriately influence (bias) their work. Examples of potential conflicts of interest include employment, consultancies, stock ownership, honoraria, paid expert testimony, patent applications/ registrations, and grants or other funding. Authors should complete the declaration of competing interest statement using this template and upload to the submission system at the Attach/Upload Files step. Note: Please do not convert the .docx template to another file type. Author signatures are not required. If there are no interests to declare, please choose the first option in the template. More information. At the end of the text, under a subheading 'Conflict of interest statement', all authors must disclose any financial and personal relationships with other people or organisations that could inappropriately influence (bias) their work. Examples of potential conflicts of interest include employment, consultancies, stock ownership, honoraria, paid expert testimony, patent applications/ registrations, and grants or other funding. Submission declaration and verification Submission of an article implies that the work described has not been published previously (except in the form of an abstract, a published lecture or academic thesis, see 'Multiple, redundant or concurrent publication' for more information), that it is not under consideration for publication elsewhere, that its publication is approved by all authors and tacitly or explicitly by the responsible authorities where the work was carried out, and that, if accepted, it will not be published elsewhere in the same form, in English or in any other language, including electronically without the written consent of the copyright- holder. To verify originality, your article may be checked by the originality detection service Crossref Similarity Check.

AUTHOR INFORMATION PACK 1 Oct 2021 www.elsevier.com/locate/ctarc 19 Preprints Please note that preprints can be shared anywhere at any time, in line with Elsevier's sharing policy. Sharing your preprints e.g. on a preprint server will not count as prior publication (see 'Multiple, redundant or concurrent publication' for more information). Use of inclusive language Inclusive language acknowledges diversity, conveys respect to all people, is sensitive to differences, and promotes equal opportunities. Content should make no assumptions about the beliefs or commitments of any reader; contain nothing which might imply that one individual is superior to another on the grounds of age, gender, race, ethnicity, culture, sexual orientation, disability or health condition; and use inclusive language throughout. Authors should ensure that writing is free from bias, stereotypes, slang, reference to dominant culture and/or cultural assumptions. We advise to seek gender neutrality by using plural nouns ("clinicians, patients/clients") as default/wherever possible to avoid using "he, she," or "he/she." We recommend avoiding the use of descriptors that refer to personal attributes such as age, gender, race, ethnicity, culture, sexual orientation, disability or health condition unless they are relevant and valid. These guidelines are meant as a point of reference to help identify appropriate language but are by no means exhaustive or definitive. Author contributions For transparency, we encourage authors to submit an author statement file outlining their individual contributions to the paper using the relevant CRediT roles: Conceptualization; Data curation; Formal analysis; Funding acquisition; Investigation; Methodology; Project administration; Resources; Software; Supervision; Validation; Visualization; Roles/Writing - original draft; Writing - review & editing. Authorship statements should be formatted with the names of authors first and CRediT role(s) following. More details and an example When submitting a paper authors must complete the Authorship form download from https://www.elsevier.com/__data/promis_misc/authorship_ctrc.pdf. This form confirms that all authors agree to publication if the paper is accepted and allows authors to declare any conflicts of interest, sources of funding and ethical approval (if required). Please download the form and submit it with your paper. Submissions that do not include a completed form will be returned without review. Changes to authorship Authors are expected to consider carefully the list and order of authors before submitting their manuscript and provide the definitive list of authors at the time of the original submission. Any addition, deletion or rearrangement of author names in the authorship list should be made only before the manuscript has been accepted and only if approved by the journal Editor. To request such a change, the Editor must receive the following from the corresponding author: (a) the reason for the change in author list and (b) written confirmation (e-mail, letter) from all authors that they agree with the addition, removal or rearrangement. In the case of addition or removal of authors, this includes confirmation from the author being added or removed. Only in exceptional circumstances will the Editor consider the addition, deletion or rearrangement of authors after the manuscript has been accepted. While the Editor considers the request, publication of the manuscript will be suspended. If the manuscript has already been published in an online issue, any requests approved by the Editor will result in a corrigendum. Copyright Upon acceptance of an article, authors will be asked to complete a 'License Agreement' (see more information on this). Permitted third party reuse of open access articles is determined by the author's choice of user license.

Author rights As an author you (or your employer or institution) have certain rights to reuse your work. More information. Elsevier supports responsible sharing Find out how you can share your research published in Elsevier journals.

AUTHOR INFORMATION PACK 1 Oct 2021 www.elsevier.com/locate/ctarc 20 Role of the funding source You are requested to identify who provided financial support for the conduct of the research and/or preparation of the article and to briefly describe the role of the sponsor(s), if any, in study design; in the collection, analysis and interpretation of data; in the writing of the report; and in the decision to submit the article for publication. If the funding source(s) had no such involvement then this should be stated. All sources of funding should be declared as an acknowledgement at the end of the text. Authors should declare the role of study sponsors, if any, in the collection, analysis and interpretation of data; in the writing of the manuscript; and in the decision to submit the manuscript for publication. If the study sponsors had no such involvement, the authors should so state. Open access Please visit our Open Access page for more information. Cancer Treatment and Research Communications continues with the same aims and scope, editorial team, submission system and rigorous peer review.

Please note: : All authors of accepted papers which are submitted to Cancer Treatment and Research Communications before 31st of December 2021, will be entitled to a 50% discount on the APC. Elsevier Researcher Academy Researcher Academy is a free e-learning platform designed to support early and mid-career researchers throughout their research journey. The "Learn" environment at Researcher Academy offers several interactive modules, webinars, downloadable guides and resources to guide you through the process of writing for research and going through peer review. Feel free to use these free resources to improve your submission and navigate the publication process with ease. Please write your text in good English (American or British usage is accepted, but not a mixture of these). Authors who feel their English language manuscript may require editing to eliminate possible grammatical or spelling errors and to conform to correct scientific English may wish to use the English Language Editing service available from Elsevier's WebShop. Please note the journal also offers complimentary language editing at the discretion of the editor. Submission Our online submission system guides you stepwise through the process of entering your article details and uploading your files. The system converts your article files to a single PDF file used in the peer-review process. Editable files (e.g., Word, LaTeX) are required to typeset your article for final publication. All correspondence, including notification of the Editor's decision and requests for revision, is sent by e-mail. Online Submission of Manuscripts Submission and peer review of all papers is conducted entirely online, increasing efficiency for editors, authors, and reviewers, and enhancing publication speed. Authors requesting further information on online submission are strongly encouraged to view the system, including a tutorial, at https://www.editorialmanager.com/ctc/default.aspx. For any additional enquiries please visit our Support Center.

You may also provide the names and contact addresses (including e-mail) of two potential reviewers that have not been involved with the case and are not co-workers. These may or may not be used at the Editor's discretion.

'Uniform Requirements These guidelines generally follow the 'Uniform Requirements for Manuscripts Submitted to Biomedical Journals , published by the International Committee of Medical Journal Editors (ICMJE). The complete document appears at http://www.icmje.org. Submit your article Please submit your article via https://www.editorialmanager.com/ctc/default.aspx. PREPARATION

AUTHOR INFORMATION PACK 1 Oct 2021 www.elsevier.com/locate/ctarc 21 Queries For questions about the editorial process (including the status of manuscripts under review) or for technical support on submissions, please visit our Support Center. NEW SUBMISSIONS Submission to this journal proceeds totally online and you will be guided stepwise through the creation and uploading of your files. The system automatically converts your files to a single PDF file, which is used in the peer-review process. As part of the Your Paper Your Way service, you may choose to submit your manuscript as a single file to be used in the refereeing process. This can be a PDF file or a Word document, in any format or lay- out that can be used by referees to evaluate your manuscript. It should contain high enough quality figures for refereeing. If you prefer to do so, you may still provide all or some of the source files at the initial submission. Please note that individual figure files larger than 10 MB must be uploaded separately. References There are no strict requirements on reference formatting at submission. References can be in any style or format as long as the style is consistent. Where applicable, author(s) name(s), journal title/ book title, chapter title/article title, year of publication, volume number/book chapter and the article number or pagination must be present. Use of DOI is highly encouraged. The reference style used by the journal will be applied to the accepted article by Elsevier at the proof stage. Note that missing data will be highlighted at proof stage for the author to correct. Formatting requirements There are no strict formatting requirements but all manuscripts must contain the essential elements needed to convey your manuscript, for example Abstract, Keywords, Introduction, Materials and Methods, Results, Conclusions, Artwork and Tables with Captions. If your article includes any Videos and/or other Supplementary material, this should be included in your initial submission for peer review purposes. Divide the article into clearly defined sections. Figures and tables embedded in text Please ensure the figures and the tables included in the single file are placed next to the relevant text in the manuscript, rather than at the bottom or the top of the file. The corresponding caption should be placed directly below the figure or table. Peer review This journal operates a single anonymized review process. All contributions will be initially assessed by the editor for suitability for the journal. Papers deemed suitable are then typically sent to a minimum of two independent expert reviewers to assess the scientific quality of the paper. The Editor is responsible for the final decision regarding acceptance or rejection of articles. The Editor's decision is final. Editors are not involved in decisions about papers which they have written themselves or have been written by family members or colleagues or which relate to products or services in which the editor has an interest. Any such submission is subject to all of the journal's usual procedures, with peer review handled independently of the relevant editor and their research groups. More information on types of peer review. REVISED SUBMISSIONS Use of word processing software Regardless of the file format of the original submission, at revision you must provide us with an editable file of the entire article. Keep the layout of the text as simple as possible. Most formatting codes will be removed and replaced on processing the article. The electronic text should be prepared in a way very similar to that of conventional manuscripts (see also the Guide to Publishing with Elsevier). See also the section on Electronic artwork. To avoid unnecessary errors you are strongly advised to use the 'spell-check' and 'grammar-check' functions of your word processor. Article structure In general, articles should conform to the conventional structure of Abstract, Introduction, Presentation of Case, Discussion, Conclusion, Consent, Conflict of Interest Statement and References plus figures and/or tables.

AUTHOR INFORMATION PACK 1 Oct 2021 www.elsevier.com/locate/ctarc 22 Introduction State the objectives of the work and provide an adequate background, avoiding a detailed literature survey or a summary of the results. Essential title page information • Title. Concise and informative. Titles are often used in information-retrieval systems. Avoid abbreviations and formulae where possible. • Author names and affiliations. Please clearly indicate the given name(s) and family name(s) of each author and check that all names are accurately spelled. You can add your name between parentheses in your own script behind the English transliteration. Present the authors' affiliation addresses (where the actual work was done) below the names. Indicate all affiliations with a lower- case superscript letter immediately after the author's name and in front of the appropriate address. Provide the full postal address of each affiliation, including the country name and, if available, the e-mail address of each author. • Corresponding author. Clearly indicate who will handle correspondence at all stages of refereeing and publication, also post-publication. This responsibility includes answering any future queries about Methodology and Materials. Ensure that the e-mail address is given and that contact details are kept up to date by the corresponding author. • Present/permanent address. If an author has moved since the work described in the article was done, or was visiting at the time, a 'Present address' (or 'Permanent address') may be indicated as a footnote to that author's name. The address at which the author actually did the work must be retained as the main, affiliation address. Superscript Arabic numerals are used for such footnotes. Twitter handle If you would like your Twitter handle to be included on your published paper, please provide it on your title page Highlights Highlights are optional yet highly encouraged for this journal, as they increase the discoverability of your article via search engines. They consist of a short collection of bullet points that capture the novel results of your research as well as new methods that were used during the study (if any). Please have a look at the examples here: example Highlights.

Highlights should be submitted in a separate editable file in the online submission system. Please use 'Highlights' in the file name and include 3 to 5 bullet points (maximum 85 characters, including spaces, per bullet point). Cover Letter All submissions must be accompanied by a cover letter in which the significance of the results is outlined. This Cover Letter must be on Institution Letterhead. Abstract A concise and factual abstract is required. The abstract should state briefly the purpose of the research, the principal results and major conclusions. An abstract is often presented separately from the article, so it must be able to stand alone. For this reason, References should be avoided, but if essential, then cite the author(s) and year(s). Also, non-standard or uncommon abbreviations should be avoided, but if essential they must be defined at their first mention in the abstract itself. The abstracts should be structured as follows:

The abstract should not exceed 250 words, and summarize the materials, methods, results, and significant conclusions reported in the manuscript. Citations in the abstract must be given in full. On the same page, supply an alphabetical list of nonstandard abbreviations used in the paper three or more times, with their full definitions. Keywords Immediately after the abstract, provide a maximum of 6 keywords, using American spelling and avoiding general and plural terms and multiple concepts (avoid, for example, 'and', 'of'). Be sparing with abbreviations: only abbreviations firmly established in the field may be eligible. These keywords will be used for indexing purposes.

AUTHOR INFORMATION PACK 1 Oct 2021 www.elsevier.com/locate/ctarc 23 Abbreviations Define abbreviations that are not standard in this field in a footnote to be placed on the first page of the article. Such abbreviations that are unavoidable in the abstract must be defined at their first mention there, as well as in the footnote. Ensure consistency of abbreviations throughout the article. Acknowledgements Collate acknowledgements in a separate section at the end of the article before the references and do not, therefore, include them on the title page, as a footnote to the title or otherwise. List here those individuals who provided help during the research (e.g., providing language help, writing assistance or proof reading the article, etc.). All contributors who do not meet the criteria for authorship as defined above should be listed in an acknowledgements section. Examples of those who might be acknowledged include a person who provided purely technical help, writing assistance, or a department chair who provided only general support. Authors should disclose whether they had any writing assistance and identify the entity that paid for this assistance. Formatting of funding sources List funding sources in this standard way to facilitate compliance to funder's requirements:

Funding: This work was supported by the National Institutes of Health [grant numbers xxxx, yyyy]; the Bill & Melinda Gates Foundation, Seattle, WA [grant number zzzz]; and the United States Institutes of Peace [grant number aaaa].

It is not necessary to include detailed descriptions on the program or type of grants and awards. When funding is from a block grant or other resources available to a university, college, or other research institution, submit the name of the institute or organization that provided the funding.

If no funding has been provided for the research, please include the following sentence:

This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. Units Follow internationally accepted rules and conventions: use the international system of units (SI). If other units are mentioned, please give their equivalent in SI. Units and Abbreviations Follow internationally accepted rules and conventions: use the international system of units (SI). Conventions for abbreviations should be those detailed in: Baron DN, ed. Units, Symbols, and Abbreviations: A Guide for Biological and Medical Editors and Authors. 5th edition. London: Royal Society of Medicine Services, 1994. Footnotes Footnotes should be used sparingly. Number them consecutively throughout the article. Many word processors build footnotes into the text, and this feature may be used. Should this not be the case, indicate the position of footnotes in the text and present the footnotes themselves separately at the end of the article. Artwork Figures of good quality should be submitted online as separate files. For detailed instructions on the preparation of electronic artwork, consult the Artwork Instructions to Authors: https://www.elsevier.com/artworkinstructions. Permission to reproduce illustrations should always be obtained before submission and details included with the captions. To help authors submit high-quality artwork early in the process, the Artwork Quality Control Tool automatically checks the submitted artwork and other file types when they are first uploaded against the artwork requirements outlined in the Artwork Instructions to Authors. Each figure/file is checked only once, so further along in the process only new uploaded files will be checked. Electronic artwork General points • Make sure you use uniform lettering and sizing of your original artwork. • Preferred fonts: Arial (or Helvetica), Times New Roman (or Times), Symbol, Courier. • Number the illustrations according to their sequence in the text.

AUTHOR INFORMATION PACK 1 Oct 2021 www.elsevier.com/locate/ctarc 24 • Use a logical naming convention for your artwork files. • Indicate per figure if it is a single, 1.5 or 2-column fitting image. • For Word submissions only, you may still provide figures and their captions, and tables within a single file at the revision stage. • Please note that individual figure files larger than 10 MB must be provided in separate source files.

A detailed guide on electronic artwork is available. You are urged to visit this site; some excerpts from the detailed information are given here. Formats Regardless of the application used, when your electronic artwork is finalized, please 'save as' or convert the images to one of the following formats (note the resolution requirements for line drawings, halftones, and line/halftone combinations given below): EPS (or PDF): Vector drawings. Embed the font or save the text as 'graphics'. TIFF (or JPG): Color or grayscale photographs (halftones): always use a minimum of 300 dpi. TIFF (or JPG): Bitmapped line drawings: use a minimum of 1000 dpi. TIFF (or JPG): Combinations bitmapped line/half-tone (color or grayscale): a minimum of 500 dpi is required. Please do not: • Supply files that are optimized for screen use (e.g., GIF, BMP, PICT, WPG); the resolution is too low. • Supply files that are too low in resolution. • Submit graphics that are disproportionately large for the content. Illustration services Elsevier's Author Services offers Illustration Services to authors preparing to submit a manuscript but concerned about the quality of the images accompanying their article. Elsevier's expert illustrators can produce scientific, technical and medical-style images, as well as a full range of charts, tables and graphs. Image 'polishing' is also available, where our illustrators take your image(s) and improve them to a professional standard. Please visit the website to find out more. Figure captions Ensure that each illustration has a caption. A caption should comprise a brief title (not on the figure itself) and a description of the illustration. Keep text in the illustrations themselves to a minimum but explain all symbols and abbreviations used. Tables Please submit tables as editable text and not as images. Tables can be placed either next to the relevant text in the article, or on separate page(s) at the end. Number tables consecutively in accordance with their appearance in the text and place any table notes below the table body. Be sparing in the use of tables and ensure that the data presented in them do not duplicate results described elsewhere in the article. Please avoid using vertical rules and shading in table cells. Tables should be submitted online as a separate file, bear a short descriptive title, and be numbered in Arabic numbers. Tables should be cited in the text.

Referees

Each submitted manuscript is required to include at least three suggested reviewers, with affiliations, and email addresses. Authors should consider carefully their suggested reviewers. Suggested reviewers should not have a conflict of interest for the submitted manuscript, nor have substantial ties to the authors of the manuscript. Email addresses must be from the suggested reviewer's institutional affiliation, not a non-specific, generic email address. Suggested reviewers should have expertise in the subject matter of the submitted manuscript. For more details, visit our Support site. Note that the editor retains the sole right to decide whether or not the suggested reviewers are used. References Data references This journal encourages you to cite underlying or relevant datasets in your manuscript by citing them in your text and including a data reference in your Reference List. Data references should include the following elements: author name(s), dataset title, data repository, version (where available), year, and global persistent identifier. Add [dataset] immediately before the reference so we can properly identify it as a data reference. The [dataset] identifier will not appear in your published article.

AUTHOR INFORMATION PACK 1 Oct 2021 www.elsevier.com/locate/ctarc 25 Reference management software Most Elsevier journals have their reference template available in many of the most popular reference management software products. These include all products that support Citation Style Language styles, such as Mendeley. Using citation plug-ins from these products, authors only need to select the appropriate journal template when preparing their article, after which citations and bibliographies will be automatically formatted in the journal's style. If no template is yet available for this journal, please follow the format of the sample references and citations as shown in this Guide. If you use reference management software, please ensure that you remove all field codes before submitting the electronic manuscript. More information on how to remove field codes from different reference management software. Users of Mendeley Desktop can easily install the reference style for this journal by clicking the following link: http://open.mendeley.com/use-citation-style/cancer-treatment-communications When preparing your manuscript, you will then be able to select this style using the Mendeley plug- ins for Microsoft Word or LibreOffice. Reference formatting There are no strict requirements on reference formatting at submission. References can be in any style or format as long as the style is consistent. Where applicable, author(s) name(s), journal title/ book title, chapter title/article title, year of publication, volume number/book chapter and the article number or pagination must be present. Use of DOI is highly encouraged. The reference style used by the journal will be applied to the accepted article by Elsevier at the proof stage. Note that missing data will be highlighted at proof stage for the author to correct. If you do wish to format the references yourself they should be arranged according to the following examples: Journal abbreviations source Journal names should be abbreviated according to the List of Title Word Abbreviations. Video Elsevier accepts video material and animation sequences to support and enhance your scientific research. Authors who have video or animation files that they wish to submit with their article are strongly encouraged to include links to these within the body of the article. This can be done in the same way as a figure or table by referring to the video or animation content and noting in the body text where it should be placed. All submitted files should be properly labeled so that they directly relate to the video file's content. In order to ensure that your video or animation material is directly usable, please provide the file in one of our recommended file formats with a preferred maximum size of 150 MB per file, 1 GB in total. Video and animation files supplied will be published online in the electronic version of your article in Elsevier Web products, including ScienceDirect. Please supply 'stills' with your files: you can choose any frame from the video or animation or make a separate image. These will be used instead of standard icons and will personalize the link to your video data. For more detailed instructions please visit our video instruction pages. Note: since video and animation cannot be embedded in the print version of the journal, please provide text for both the electronic and the print version for the portions of the article that refer to this content. Data visualization Include interactive data visualizations in your publication and let your readers interact and engage more closely with your research. Follow the instructions here to find out about available data visualization options and how to include them with your article. Supplementary material Supplementary material such as applications, images and sound clips, can be published with your article to enhance it. Submitted supplementary items are published exactly as they are received (Excel or PowerPoint files will appear as such online). Please submit your material together with the article and supply a concise, descriptive caption for each supplementary file. If you wish to make changes to supplementary material during any stage of the process, please make sure to provide an updated file. Do not annotate any corrections on a previous version. Please switch off the 'Track Changes' option in Microsoft Office files as these will appear in the published version.

AUTHOR INFORMATION PACK 1 Oct 2021 www.elsevier.com/locate/ctarc 26 Research data This journal encourages and enables you to share data that supports your research publication where appropriate, and enables you to interlink the data with your published articles. Research data refers to the results of observations or experimentation that validate research findings. To facilitate reproducibility and data reuse, this journal also encourages you to share your software, code, models, algorithms, protocols, methods and other useful materials related to the project.

Below are a number of ways in which you can associate data with your article or make a statement about the availability of your data when submitting your manuscript. If you are sharing data in one of these ways, you are encouraged to cite the data in your manuscript and reference list. Please refer to the "References" section for more information about data citation. For more information on depositing, sharing and using research data and other relevant research materials, visit the research data page. Data linking If you have made your research data available in a data repository, you can link your article directly to the dataset. Elsevier collaborates with a number of repositories to link articles on ScienceDirect with relevant repositories, giving readers access to underlying data that gives them a better understanding of the research described.

There are different ways to link your datasets to your article. When available, you can directly link your dataset to your article by providing the relevant information in the submission system. For more information, visit the database linking page.

For supported data repositories a repository banner will automatically appear next to your published article on ScienceDirect.

In addition, you can link to relevant data or entities through identifiers within the text of your manuscript, using the following format: Database: xxxx (e.g., TAIR: AT1G01020; CCDC: 734053; PDB: 1XFN). Mendeley Data This journal supports Mendeley Data, enabling you to deposit any research data (including raw and processed data, video, code, software, algorithms, protocols, and methods) associated with your manuscript in a free-to-use, open access repository. During the submission process, after uploading your manuscript, you will have the opportunity to upload your relevant datasets directly to Mendeley Data. The datasets will be listed and directly accessible to readers next to your published article online.

For more information, visit the Mendeley Data for journals page. Data statement To foster transparency, we encourage you to state the availability of your data in your submission. This may be a requirement of your funding body or institution. If your data is unavailable to access or unsuitable to post, you will have the opportunity to indicate why during the submission process, for example by stating that the research data is confidential. The statement will appear with your published article on ScienceDirect. For more information, visit the Data Statement page. AFTER ACCEPTANCE One set of page proofs in PDF format will be sent by e-mail to the corresponding author, which they are requested to correct and return within 48 hours. Elsevier sends PDF proofs that can be annotated; for this you will need to download Adobe Reader version 7 available free from http://www.adobe.com/products/acrobat/readstep2.html. Instructions on how to annotate PDF files will accompany the proofs. The exact system requirements are given at the Adobe website: http://www.adobe.com/products/acrobat/acrrsystemreqs.html#70win

If you do not wish to use the PDF annotations function, you may list the corrections (including replies to the Query Form) in an e-mail. Please list your corrections quoting line number. If, for any reason, this is not possible, then mark the corrections and any other comments (including replies to the Query Form) on a printout of your proof and return by fax, or scan the pages and e-mail, or by post.

Please use this proof only for checking the typesetting, editing, completeness and correctness of the text, tables and figures. Significant changes to the article as accepted for publication will only be considered at this stage with permission from the Editor. We will do everything possible to get your

AUTHOR INFORMATION PACK 1 Oct 2021 www.elsevier.com/locate/ctarc 27 article published quickly and accurately. Therefore, it is important to ensure that all of your corrections are sent back to us in one communication: please check carefully before replying, as inclusion of any subsequent corrections cannot be guaranteed. Proofreading is solely your responsibility. Note that Elsevier may proceed with the publication of your article if no response is received.

Reviewing Articles

For manuscripts that are accepted for publication, all of the authors and co-authors are expected to review at least two manuscripts over the two years following publication. The publication process for each submitted manuscript requires external peer-review, with significant time, effort, and input from its voluntary reviewers. Therefore, it is appropriate that those authors who have benefited from the peer process should, in turn, be willing to peer-review other authors' manuscripts. Online proof correction To ensure a fast publication process of the article, we kindly ask authors to provide us with their proof corrections within two days. Corresponding authors will receive an e-mail with a link to our online proofing system, allowing annotation and correction of proofs online. The environment is similar to MS Word: in addition to editing text, you can also comment on figures/tables and answer questions from the Copy Editor. Web-based proofing provides a faster and less error-prone process by allowing you to directly type your corrections, eliminating the potential introduction of errors. If preferred, you can still choose to annotate and upload your edits on the PDF version. All instructions for proofing will be given in the e-mail we send to authors, including alternative methods to the online version and PDF. We will do everything possible to get your article published quickly and accurately. Please use this proof only for checking the typesetting, editing, completeness and correctness of the text, tables and figures. Significant changes to the article as accepted for publication will only be considered at this stage with permission from the Editor. It is important to ensure that all corrections are sent back to us in one communication. Please check carefully before replying, as inclusion of any subsequent corrections cannot be guaranteed. Proofreading is solely your responsibility. Offprints The corresponding author will be notified and receive a link to the published version of the open access article on ScienceDirect. This link is in the form of an article DOI link which can be shared via email and social networks. For an extra charge, paper offprints can be ordered via the offprint order form which is sent once the article is accepted for publication. Both corresponding and co-authors may order offprints at any time via Elsevier's Author Services. AUTHOR INQUIRIES Visit the Elsevier Support Center to find the answers you need. Here you will find everything from Frequently Asked Questions to ways to get in touch. You can also check the status of your submitted article or find out when your accepted article will be published.

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