CORE Metadata, citation and similar papers at core.ac.uk Provided by Ghent University Academic Bibliography Article In Vitro Rumen Simulations Show a Reduced Disappearance of Deoxynivalenol, Nivalenol and Enniatin B at Conditions of Rumen Acidosis and Lower Microbial Activity Sandra Debevere 1,2, An Cools 3, Siegrid De Baere 1, Geert Haesaert 4, Michael Rychlik 5, Siska Croubels 1,† and Veerle Fievez 2,*,† 1 Department of Pharmacology, Toxicology and Biochemistry, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium;
[email protected] (S.D.);
[email protected] (S.D.B.);
[email protected] (S.C.) 2 Department of Animal Sciences and Aquatic Ecology, Faculty of Bioscience Engineering, Ghent University, Coupure links 653, 9000 Ghent, Belgium 3 Department of Nutrition, Genetics and Ethology, Faculty of Veterinary Medicine, Ghent University, Heidestraat 19, 9820 Merelbeke, Belgium;
[email protected] 4 Department of Plants and Crops, Faculty of Bioscience Engineering, Ghent University, Valentin Vaerwyckweg 1, 9000 Ghent, Belgium;
[email protected] 5 Chair of Analytical Food Chemistry, Technical University of Munich, Maximus-von-Imhof-Forum 2, 85354 Freising, Germany;
[email protected] * Correspondence:
[email protected]; Tel.: +32-9-264-9002 † Shared last author. Received: 3 January 2020; Accepted: 31 January 2020; Published: 5 February 2020 Abstract: Ruminants are generally considered to be less susceptible to the effects of mycotoxins than monogastric animals as the rumen microbiota are capable of detoxifying some of these toxins. Despite this potential degradation, mycotoxin-associated subclinical health problems are seen in dairy cows. In this research, the disappearance of several mycotoxins was determined in an in vitro rumen model and the effect of realistic concentrations of those mycotoxins on fermentation was assessed by volatile fatty acid production.