Survival of Cancer Patients in Northern Ireland: 1993-2004
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Survival of cancer patients in NorthernSurvival patients of cancer Ireland: Survival of cancer patients in Northern Ireland: 1993-2004 October 2007 1993-2004 Northern Ireland Cancer Registry Centre for Clinical and Population Sciences Mulhouse Building Grosvenor Road Belfast BT12 6BJ 5 Tel: (44) 028 9063 2573 Fax: (44) 028 9024 8017 Email: [email protected] Website: www.qub.ac.uk/nicr Contents CONTENTS CONTENTS ...................................................................................................................................................... I FOREWORD .................................................................................................................................................. III ACKNOWLEDGEMENTS .............................................................................................................................. IV 01: INTRODUCTION....................................................................................................................................... 1 02: CANCER IN NORTHERN IRELAND........................................................................................................ 7 03: ALL CANCERS (EXCLUDING NON-MELANOMA SKIN CANCER) (C00-C97, EX. C44).......................................... 13 04: CANCER OF THE LIP, ORAL CAVITY & PHARYNX (C00-C14)............................................................. 19 05: OESOPHAGEAL CANCER (C15)............................................................................................................ 22 06: STOMACH CANCER (C16)...................................................................................................................... 27 07: COLORECTAL CANCER (COLON, RECTOSIGMOID JUNCTION & ANUS) (C18-C21) ....................................... 32 08: CANCER OF THE COLON (C18)............................................................................................................. 40 09: CANCER OF THE RECTUM, RECTOSIGMOID JUNCTION & ANUS (C19-C21) ................................... 45 10: LIVER CANCER (C22) ............................................................................................................................. 49 11: PANCREATIC CANCER (C25) ................................................................................................................ 52 12: CANCER OF THE LARYNX (C32)........................................................................................................... 55 13: LUNG CANCER (TRACHEA, BRONCHUS & LUNG) (C33-C34) ........................................................................ 58 14: MALIGNANT MELANOMA (C43) ............................................................................................................ 65 15: MESOTHELIOMA (C45)........................................................................................................................... 71 16: BREAST CANCER (FEMALES ONLY) (C50)................................................................................................ 73 17: CERVICAL CANCER (C53) ..................................................................................................................... 79 18: CANCER OF THE UTERUS (C54)........................................................................................................... 84 19: OVARIAN CANCER (C56) ....................................................................................................................... 88 20: PROSTATE CANCER (C61) .................................................................................................................... 93 21: TESTICULAR CANCER (C62) ................................................................................................................. 99 22: CANCER OF THE KIDNEY (C64-C66, C68)............................................................................................. 102 23: CANCER OF THE BLADDER (C67) ...................................................................................................... 107 24: CANCER OF THE BRAIN (C71) ............................................................................................................ 112 25: HODGKIN’S DISEASE (C81) ................................................................................................................. 115 26: NON-HODGKIN’S LYMPHOMA (C82-C85, C96) ..................................................................................... 118 27: MULTIPLE MYELOMA (C90)................................................................................................................. 123 28: LEUKAEMIA (C91-C95)........................................................................................................................... 126 29: CHILDHOOD CANCER (AGES 0-14; ALL CANCERS EXCLUDING NMSC)..................................................... 132 A1: ABBREVIATIONS ................................................................................................................................ 135 A2: DEFINITIONS ....................................................................................................................................... 136 A3: STAGING.............................................................................................................................................. 140 A4: INCIDENCE RATES BY SEX AND CANCER SITE (1993-2004) ........................................................... 142 Northern Ireland Cancer Registry i Survival of cancer patients in Northern Ireland: 1993-2004 A5: MORTALITY RATES BY SEX AND CANCER SITE (1993-2004) .......................................................... 150 A6: ANNUAL PERCENTAGE CHANGES BY SEX AND CANCER SITE (1993-2004) ................................ 157 A7: RELATIVE SURVIVAL BY SEX AND CANCER SITE (1993-2004) ....................................................... 159 A8: RELATIVE SURVIVAL BY SEX, AGE AND CANCER SITE (1993-2003) ............................................. 160 REFERENCES ............................................................................................................................................ 166 ii Foreword FOREWORD Survival is a measure of many aspects of cancer care including delays in diagnosis, the standard of treatment, its timeliness and the overall quality of care. There have been many recent changes to Cancer Services in Northern Ireland; such as advice on alarm symptoms; screening for breast and cervical cancer and the re-organisation of cancer services with the aim of all patients having the highest standards of care irrespective of where they live. These survival statistics provide a window through which we can measure the impact of change and even though the time of follow up is short it is pleasing to note detectable improvements. This report uses new techniques to analyse survival providing us with more up to date data than previously possible. It highlights the importance of cancer registration which allows the measurement of results on a population basis giving a complete picture and not just those treated in ‘centres of excellence’. While measuring improvements, this data also highlights areas where survival has remained unchanged and where we need to concentrate our efforts. The good news is that survival has improved in both males and females diagnosed from 1997 to 2000 compared with 1993 to 1996. Once again this report emphasises the importance of smoking in the changing patterns of cancer incidence. While lung cancer in men is beginning to decrease, linked with a fall in smoking there is sadly no corresponding decrease among females as they continue to smoke; clearly an area for targeted prevention. Unfortunately smoking levels affect overall survival as tobacco related cancers tend to have poorer survival. Similarly smoking also explains in part the differences in cancer experience linked with social deprivation. Northern Ireland’s inclusion for the first time, in Eurocare – a pan-European comparison of survival highlights areas where we are doing well and others where improvements are necessary. Much has been achieved and there is still much to do. As Chairman of the N. Ireland Cancer Registry I congratulate Dr David Donnelly, Dr Anna Gavin and the Registry team for the huge amount of work compiling this report. It has highlighted our cancer survival improvements and where further improvements are possible. Prof. Roy Spence OBE MA MD FRCS Consultant Surgeon Chairman of Council of Northern Ireland Cancer Registry Northern Ireland Cancer Registry iii Survival of cancer patients in Northern Ireland: 1993-2004 ACKNOWLEDGEMENTS The Northern Ireland Cancer Registry is funded by the Department of Health, Social Services & Public Safety Northern Ireland (DHSSPSNI). The work of the Northern Ireland Cancer Registry, including the production of this report, is the result of work by the team listed below: Bernadette Anderson Finian Bannon Denise Catney Linda Caughley Olwyn Dawson David Donnelly Kate Donnelly Deirdre Fitzpatrick Donna Floyd Colin Fox Wendy Hamill Anita Jones Jackie Kelly Gavin Kennedy Heather Kinnear Julie McConnell Susan McGookin Richard Middleton Eamon O’Callaghan Guilio Napolitano Lisa Ranaghan Breige Torrans Timothy Vennard Rosemary Ward The loan of David Donnelly by the Northern Ireland Statistics and Research Agency (NISRA) is gratefully acknowledged. Special thanks are due to Riccardo Capocaccia and the EUROCARE working group for provision of EUROCARE-4 data prior to its publication in August 2007. Thanks also to Paul Walsh from the National