Meeting Program Hilton Atlanta May 6-9, 2015 Commercial Support Future Annual As of March 26, 2015 Meetings 75th Annual Meeting Abbvie May 11-14, 2016 The Westin Kierland Resort & Spa Actelion Scottsdale, Arizona

Amgen 76th Annual Meeting MISSION April 26-29, 2017 Hilton Portland & Executive Tower The SID mission is to advance and Anacor Portland, Oregon promote the sciences relevant to skin Celgene health and disease through education, JID- 2018 advocacy and scholarly exchange of Eli Lilly May 16-19, 2018 scientific information. Rosen Shingle Creek Orlando, Florida 2015 Exhibitors VISION The SID will be the pre-eminent 77th Annual Meeting Cell n Tec May 8-11, 2019 organization for the science of skin Hilton Chicago health and diseases. It will be a CYTOO Chicago, Illinois leading purveyor of educational programming. It will promote a culture Elsevier Officers of discovery and serve as the premier PRESIDENT Metabolon, Inc. forum for the exchange of scientific S. Wright Caughman, MD

information relating to dermatologic VICE PRESIDENT NIAMS research. It will build cross-disciplinary Alexa B. Kimball, MD/MPH

bridges to provide catalytic leadership Pfizer PRESIDENT-ELECT in attaining intellectual, political, Mark Udey, MD/PhD and financial support for skin-related ZenBio, Inc. VICE PRESIDENT-ELECT scientific investigation. The SID will Anthony Gaspari, MD be – and be viewed as – a significant IMMEDIATE PAST PRESIDENT force in shaping public policy. As Paul R. Bergstresser, MD a result of recruiting, nurturing, and SECRETARY-TREASURER mentoring the next generation of Alice P. Pentland, MD scientists, it will be a financially robust and self-sustaining organization. ASSISTANT SECRETARY-TREASURER Richard L. Gallo, MD/PhD CORE VALUES JID EDITOR • Integrity Barbara A. Gilchrest, MD • Collegiality Board of Directors • Shared beliefs Cheng-Ming Chuong, MD/PhD • Innovation James T. Elder, MD/PhD • Leadership Janet A. Fairley, MD Maranke I. Koster, PhD Connect with the SID! Andrew P. Kowalczyk, PhD David J. Margolis, MD/PhD Anthony E. Oro, MD/PhD M. Joyce Rico, MD/MBA John Seykora, MD/PhD #SIDATL2015 Martin Weinstock, MD/PhD www.sidnet.org Check-in and check for updates at the RESIDENT/POST DOCTORAL SID 2015 Annual Meeting Facebook FELLOWS www.facebook.com/SID2015annualmeeting Fang Liu, PhD Lisa Liu, MD/PhD 1 Welcome to Atlanta

On behalf of the Society for Investigative (SID), welcome to the 2015 Annual Meeting in Atlanta. The capital city of Georgia, Atlanta has a rich history, a thriving present, and an exciting future. Home to Coca Cola, CNN, Gone with the Wind, the Atlanta Symphony Orchestra, Martin Luther King and the Civil Rights Movement, the Atlanta Braves, the busiest airport in the world, and a host of world renowned universities and research institutions, including Emory University, Georgia Institute of Technology, and the Centers for Disease Control and Prevention, Atlanta is an international hub for business, culture, entertainment, and academia.

We hope you will find time to enjoy the city’s vibrant, multicultural atmosphere, world-class restaurants, and outstanding historic and cultural attractions. Atlanta blends all the excitement of a major metropolitan center with genuine Southern charm and hospitality, and I’m confident that you will enjoy your stay.

As always, we are grateful to the Committee on Scientific Programs which has again this year planned an exciting and enlightening program for us.

SID COMMITTEE ON SCIENTIFIC PROGRAMS Co-Chairs Anthony Gaspari, MD & My Mahoney, PhD

Committee Members Sam Hwang, MD, Sarah Millar, PhD, Paul T. Nghiem, MD/PhD, Abrar A. Quareshi, MD/PhD, Nicole L. Ward, PhD, Victoria P. Werth, MD, Daniel Kaplan, MD/PhD, Ethan Lerner, MD/PhD

Since its founding in 1937, the SID has been committed to facilitating the careers of young investigators by providing a dynamic forum in which a diverse group of scientists can interact. We remain fully committed to this goal and to offer programming that reaches all members of the dermatology and cutaneous biology research communities.

We have scheduled a variety of activities to highlight scientific advances made by our community, and social events that will celebrate our international scientific community and the culture and beauty of Atlanta.

Welcome to what promises to be another truly outstanding SID Annual Meeting!

The photos of the Atlanta skyline are provided as part of a collaborative effort by Dr. Andrew Kowalczyk, Mr. Joshua Lewis, and Ms. Sara Stahley. Andrew Kowalczyk is a faculty member at Emory University in the Depart- ments of Cell Biology and Dermatology, and a member of the SID Board of Directors. Josh Lewis and Sara Stahley are PhD candidates in the Biochemistry, Cell and program in Emory University’s Laney Graduate School. Research in the Kowalczyk lab focuses on the basic biology of cell adhesion and the pathomechanisms of the S. Wright Caughman Alice P. Pentland Richard L. Gallo skin disease pemphigus vulgaris. The group’s interest in photography dovetails with their President Secretary-Treasurer Asst. Secretary-Treasurer expertise in high resolution light microscopy to gain insights into cell adhesion in develop- ment and skin disease.

2 claim CME and help the Society for Investigative Dermatology (SID)!

Attention SID 2015 Annual Meeting attendees:

The SID requests that everyone who needs CME to claim hours for its meeting. CME hours are important to claim because you need them to maintain licensure and Board Certification and credentialing.

Presentations during the four-day SID Annual Meeting cover a wide range of common and rare skin diseases and feature data on promising therapeutics but, did you know that CME educational grants also support the SID and its Members? Educational Grants allow the SID and its Committee on Scientific Programs to independently develop a meeting template with content based on the stated needs of the skin research community. This results in high quality presentations that provide objective and scientific discourse to our global audience.

In addition, feedback from CME evaluations enables the Society to employ a cycle of continuous improvement. Our abstract categories evolve in parallel with emergent areas of science. We want the data compiled from these surveys to be representative of the SID community. Your suggestions for future topics and keywords ensure that we stay on the cutting edge of discovery.

Claim your CME hours! Help yourself, and help support the SID.

3 CME Statement & Objectives University of Rochester School of Medicine and Dentistry presents…

The 2015 Society for Investigative • Facilitate interdisciplinary and/or Disclaimer Dermatology Annual Meeting collaborative investigation in clinical The information provided at this CME dermatology and skin biology to activity is for continuing education Commercial Support Statement improve research hypotheses, purposes only and is not meant to Commercial Support Acknowledgment: processes and/or techniques substitute for the independent medical This CME activity is supported by • Incorporate knowledge gained from judgment of a healthcare provider relative educational grants. A complete list of interactions between basic scientists to diagnostic and treatment options of a supporters will be published in the and clinicians into daily decision- specific patient’s medical condition. course syllabus. making Instructions on How to Receive Statement of Need Faculty Listing Credit The educational programming of the SID Activity Medical Director: In order to receive CME credit, participants is designed to develop, maintain, and/or Alice P. Pentland, MD must sign-in, review the CME information increase the abilities, skills, and profes- Chair, Department of Dermatology (accreditation, learning objectives, faculty sional performance of its target audiences. University of Rochester disclosures, etc.) and attend the CME SID CME activities will: activity. Participants should also complete 1) Disseminate updated evidence-based Summary of Faculty Disclosure/ the activity evaluation form and return it to knowledge of skin biology/disease Conflict Resolution the appropriate representative following and applications for maintaining the CME activity. Participants should also health and preventing, diagnosing, Staff and Content Validation Reviewer complete the activity evaluation form and and treating disease in a manner that Disclosure return it to the Society for Investigative fosters scientific excellence, elevates The staff involved with this activity and any Dermatology via fax to 216.579.9333 or the standard of care, and meets high content validation reviewers of this activity mail to: ethical standards. have reported no relevant financial 2) Provide target audiences with a relationships with commercial interests. Society for Investigative Dermatology relevant forum for the exchange of CME cutting-edge scientific ideas, Resolution of Conflicts of Interest 526 Superior Avenue E, Suite 540 information, and methodology. In accordance with the ACCME Standards Cleveland, OH 44114 3) Advance the science involved in basic of Commercial Support of CME, the Uni- skin biology and clinical care of versity of Rochester School of Medicine Accreditation Statement patients with skin disease. and Dentistry will implement mechanisms, This activity has been planned and 4) Provide exposure to novel science prior to the planning and implementation implemented in accordance with the (both concepts and methods) which of this CME activity, to identify and resolve accreditation requirements and policies may be relevant in the future to conflicts of interest for all individuals in of the Accreditation Council for understanding and treatment a position to control content of this CME Continuing Medical Education skin disease. activity. (ACCME) through the joint providership of the University of Rochester School of Target Audience Unapproved Use Disclosure Medicine and Dentistry and the Society The primary target audiences for SID CME Statement for Investigative Dermatology. The activities include all of the sectors of the The University of Rochester requires University of Rochester School of dermatology community, consisting of CME faculty (speakers) to disclose to Medicine and Dentistry is accredited research investigators, clinicians, research attendees when products or procedures by the ACCME to provide continuing and clinical trainees, members of industry, being discussed are off-label, unlabeled, medical education for physicians. and community advocates for skin health/ experimental, and/or investigational (not disease. FDA approved); and any limitations on CERTIFICATION the information that is presented, such as The University of Rochester School of Learning Objectives data that are preliminary or that represent Medicine and Dentistry designates this At the conclusion of this activity, partici- ongoing research, interim analyses, and/ live activity for a maximum of 29.25 AMA pants should be able to: or unsupported opinion. This information PRA Category 1 Credit(s)TM. Physicians • Identify which disease states require is intended solely for continuing medical should claim only the credit commensurate new or additional research education and is not intended to promote with the extent of their participation in the • Evaluate state-of-the-are information off-label use of these medications. If you activity. relating to basic skin biology research have questions, contact the medical • Describe how newly discovered, affairs department of the manufacturer for evidence-based scientific information the most recent prescribing information. may or may not be applied to the cur- Faculty will not be discussing information rent practice of investigative or clinical about pharmaceutical agents that is outside dermatology of U.S. Food and Drug Administration • Apply strategies to structure and approved labeling. design successful research proposals, abstracts, and manuscripts

4 2015 Educational Tracks Y Young Investigator/Trainee Track I Inflammatory Skin Disease S Skin Cancer MEETING-AT-A-GLANCE

Tuesday, May 5, 2015 Thursday, May 7, 2015 ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Pachyonychia Congenita Project (PC Project) 1:00 pm – 4:10 pm Pediatric Dermatology Research Alliance/ 7:00 am – 8:00 am Symposium Society for Pediatric Dermatology Session Salon C, Hilton Atlanta Rooms 204-207, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Resident Retreat for Future Academicians 4:30 pm – 9:30 pm Registration 7:30 am – 5:00 pm Salon D, Hilton Atlanta S Convention Registration Area, First Floor, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Resident/PhD Retreat Dinner 6:00 pm – 7:30 pm Plenary Session I 8:00 am – 9:00 am Grand Ballroom, Hilton Atlanta Salon E, Hilton Atlanta I ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Eugene M. Farber Lecture 9:00 am – 9:30 am PhD Retreat 7:30 pm – 9:30 pm A Natural History of Salon C, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Christopher E.M. Griffiths, MD, FRCP, FMedSci Grand Ballroom, Hilton Atlanta I ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Wednesday, May 6, 2015 Naomi M. Kanof Lecture 9:30 am – 10:00 am ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Silencing the Sézary Cell – Past, Present, & Future Pachyonychia Congenita Project (PC Project) 7:00 am – 12:00 pm Madeleine Duvic, MD Symposium Grand Ballroom, Hilton Atlanta Salon C, Hilton Atlanta Y I ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Clinical Scholars Program Session 1 10:00 am – 12:00 pm Resident Retreat for Future Academicians 7:00 am – 3:00 pm Co-Morbidities: Skin & Systemic Disease Salon D, Hilton Atlanta By Invitation Only Grand Ballroom, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– PhD Retreat for Future Investigators 7:00 am – 3:00 pm Poster Session I 10:00 am – 12:00 pm Salon E, Hilton Atlanta By Invitation Only Poster #’s 001-245 Odd & #’s 246-490 Even ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Galleria Exhibit Hall, Hilton Atlanta SID Board of Directors Meeting 7:00 am – 2:15 pm ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Crystal Ballroom, Hilton Atlanta American DermatoEpidemiology Network 12:00 pm - 1:45 pm ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– (ADEN) Meeting Registration 8:00 am – 6:30 pm Salon C, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Convention Registration Area, First Floor, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– American and Society (AARS) 12:00 pm – 1:45 pm S Translational Science Symposium: 12:00 pm – 3:00 pm Scientific Symposium Grand Ballroom, Hilton Atlanta Immune Therapies in Skin Cancer ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Grand Ballroom, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Satellite Symposium 12:00 pm – 12:45 pm Academic-Industry Partnership Project Y Irvin H. Blank Forum 3:00 pm – 5:00 pm Getting Under Your Skin: Collaboration with Biomedical Engineers Panel Discussion 12:00 pm - 12:45 pm Salon A/B, Hilton Atlanta Grand Ballroom, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– National Rosacea Society Research Workshop 12:00 pm – 1:45 pm State-of-the-Art Plenary Lecture 1 5:00 pm - 5:30 pm Salon D, Hilton Atlanta Basic Mechanisms and Dynamics of Skin Regeneration ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Valentina Greco, PhD International Society for Cutaneous 12:00 pm – 1:45 pm Grand Ballroom, Hilton Atlanta Lymphomas/Cutaneous T-Cell Lymphoma Symposium (ISCL/CTCL) ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Room 204-207, Hilton Atlanta State-of-the-Art Plenary Lecture 2 5:30 pm - 6:00 pm ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Two Sides of a Coin: Hair Keratins in Teeth Concurrent Mini-Symposia 2:00 pm – 5:00 pm Maria I. Morasso, PhD Auto Immunity Grand Ballroom, Hilton Atlanta Salon E, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– S Carcinogenesis & Cancer President’s Welcome 6:00 pm -6:15 pm Grand Ballroom, Hilton Atlanta S. Wright Caughman, MD ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Epidemiology Kligman/Frost Leadership Lecture 6:15 pm - 6:45 pm Salon C, Hilton Atlanta The Importance of Sticking Together S I Kathleen J. Green, PhD Gene Therapy & Clinical Therapeutics Grand Ballroom, Hilton Atlanta Salon A/B, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Skin & Hair Developmental Biology American Skin Association Achievement Awards 6:45 pm – 6:55 pm Salon D, Hilton Atlanta Grand Ballroom, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Mini-Symposia Mixers 5:00 pm – 6:00 pm ASA/David Martin Carter Award 6:55 pm -7:00 pm Individual Concurrent Meeting Rooms Grand Ballroom, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– The National Eczema Association Reception – 5:00 pm – 6:30 pm Welcome Reception 7:00 pm – 9:00 pm The Decade of Eczema! Pool/Tennis Deck 3rd Floor (weather permitting) Crystal Ballroom, Hilton Atlanta or Grand Ballroom/Salon Foyer Location ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Social Event 6:30 pm - 10:30 pm Georgia Aquarium ticketed Event: Pre-Registration Required 5 Buses depart from the Hilton Atlanta beginning at 6:00 pm. Buses will begin shuttling guests back to the hotel beginning at 8:30 pm.

MEETING-AT-A-GLANCE MEETING-AT-A-GLANCE

Friday, May 8, 2015 ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Pediatric Dermatology Research Alliance/ 7:00 am – 8:00 am North American Hair Research Society- 6:00 pm – 9:30 pm Society for Pediatric Dermatology Meeting Scientific Session and Annual Business Meeting Room 204-207, Hilton Atlanta Grand Ballroom, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Registration 7:30 am – 4:00 pm National Psoriasis Foundation Scientific 6:00 pm – 9:30 pm Convention Registration Area, First Floor, Hilton Atlanta Advisory Board Meeting ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Room 203, Hilton Atlanta Business Meeting for Members 7:45 am – 8:30 am ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Grand Ballroom, Hilton Atlanta National Alopecia Areata Foundation 6:00 pm – 9:30 pm ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– (NAAF) Reception Plenary Session II 8:30 am – 9:30 am Room 206 – 207, Hilton Atlanta Grand Ballroom, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Trainee Dinner 7:00 pm - 9:00 pm S Stephen Rothman Memorial Award 9:30 am – 9:45 am Crystal Ballroom, Hilton Atlanta Presented to Ervin H. Epstein, Jr., MD Ticketed Event: Pre-registration Required Grand Ballroom, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– S Herman Beerman Lecture 9:45 am – 10:15 am Cancer immunotherapy via blockade of the PD 1 pathway Drew M. Pardoll, MD/PhD Grand Ballroom, Hilton Atlanta Saturday, May 9, 2015 ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– State-of-the-Art Plenary Lecture 3 10:15 am – 10:45 am SID Board of Directors Meeting 7:00 am – 7:45 am Translational Research in Vitiligo: Launching a New Era of Targeted Crystal Ballroom, Hilton Atlanta Treatment ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– John E. Harris, MD/PhD Registration 7:30 am – 12:00 pm Grand Ballroom, Hilton Atlanta Convention Registration Area, First Floor, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– State-of-the-Art Plenary Lecture 4 10:45 am – 11:15 am I Plenary Session III 8:00 am – 9:00 am Mitochondria as Signaling Organelles Grand Ballroom, Hilton Atlanta Navdeep S. Chandel, PhD ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Grand Ballroom, Hilton Atlanta S William Montagna Lecture 9:00 am – 9:30 am ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Therapeutic Target Practice in Melanoma Poster Session II 11:15 am – 1:15 pm Hensin Tsao, MD/PhD Poster #’s 002 - 244 Even & #’s 491 – 735 Odd Grand Ballroom, Hilton Atlanta Galleria Exhibit Hall, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– I Julius Stone Lecture 9:30 am – 10:00 am Research in Cutaneous Surgery (RCS) Meeting 12:00 pm – 1:45 pm The Multifaceted Immunoregulatory Functions of the PD-1 pathway Salon A/B, Hilton Atlanta Arlene H. Sharpe, MD/PhD ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Grand Ballroom, Hilton Atlanta Women’s Dermatologic Society Luncheon 12:00 pm – 1:45 pm ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Crystal Ballroom, Hilton Atlanta Poster Session III 10:00 am – 12:00 pm ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Poster #’s 247-489 Odd & #’s 492-736 Even I NIAID Symposium 12:00 pm – 1:45 pm Galleria Exhibit Hall, Hilton Atlanta Understanding Host Defense In Atopic ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Grand Ballroom, Hilton Atlanta Y I Clinical Scholars Program Session II 10:15 am – 12:15 pm ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Grand Ballroom, Hilton Atlanta Concurrent Mini-Symposia 2:00 pm – 5:00 pm ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– S I Clinical Research (Observations, Pathophysiology & Outcomes) Concurrent Mini-Symposia 12:30 pm – 3:30 pm Salon D, Hilton Atlanta I Adaptive Immunity & Vaccination Epidermal Structure & Barrier Function Salon D, Hilton Atlanta Salon C, Hilton Atlanta Growth Factors, Cell Adhesion & Matrix Biology Genetic Disease & Gene Regulation Salon A/B, Hilton Atlanta Rooms 204-207, Hilton Atlanta Photobiology Innate Immunity, Inflammation & Microbiology Salon C, Hilton Atlanta Salon E, Hilton Atlanta tissue Regeneration & Wound Healing Salon E, Hilton Atlanta S Pigmentation & Melanoma ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Salon A/B, Hilton Atlanta International Societies for Investigative 2:00 pm – 3:30 pm S interdisciplinary Spotlight: Skin Cancer Dermatology (ISID) Informational Meeting Grand Ballroom, Hilton Atlanta Crystal Ballroom, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Y Mini-Symposia Mixers 5:00 pm - 6:00 pm Individual Concurrent Meeting Rooms –––––––––––––––––––––––––––––––––––––––––––––––––––––––––––

6 2015 Educational Tracks

The SID is pleased to offer special educational tracks-special collections of focused topics within the 2015 Annual Meeting: The Skin Cancer, Inflam- matory Skin Disease, and Trainee Tracks. The SID has been increasing the variety of sessions offered at the Annual Meeting that are geared toward residents, fellows, students and clinicians. The Track system is an easy way for attendees identify components of the Meeting that provide in-depth coverage. Session components of each track are indicated with initials on the ‘Meeting at a Glance’ pages as follows: Skin Cancer Track (SC); Inflam- matory Skin Diseases (I); and Trainee Track (T).

Tracks include portions of the meeting that offer a density of thematic content, providing a cohesive learning experience. They also provide significant opportunities for networking and collaboration, as attendees share common clinical and research interests. Note: These Tracks merely highlight themes that run throughout the meeting. Attendees are encouraged to select sessions by conducting keyword searches for disease, mechanism, gene, etc.

Y Young Investigator/Trainee Track There are several sessions offered during the SID meeting that are designed for Trainees. They are intended to provide an overview of basic, clinical and translational science, along with opportunities to interact with senior faculty. The target audience includes medical and biomedi- cal science students, research fellows, Dermatology residents, PhD/ post-doctoral candidates, and junior faculty.

Track Components: • May 6: Irwin Blank Forum • May 7 & 9: Clinical Scholars Sessions • Round Table Discussions (during all Poster Sessions): Drop in at one of our Round Tables! An informal setting during poster sessions with experts from the SID community to help you understand poster session topics, techniques, and disease areas. • Mini-Symposia Mixers: These informal Q&A sessions will occur after all poster session topics, May 8-9 Concurrent Sessions. Mixers start at 5:00 pm to provide opportunities for interaction among meeting attendees. Light refreshments/snacks provided.

I Inflammatory Skin Disease This track includes special sessions occurring over the four-day Sid meeting and offers an in-depth view of Inflammatory Skin Diseases, both common and rare, through a variety of lenses. Presentations span the full translational continuum-from animal surrogate models to human trials, utilizing genetic, mechanistic, epidemiological, and technical approaches.

Track Components: • May 7: Eugene Farber Lecture • May 7: Naomi M. Kanof Lecture • May 7: Clinical Scholars Plenary Session • May 7: Mini-Symposium - Gene Therapy & Clinical Therapeutics • May 8: NIAID Symposium • May 8: Mini-Symposium - Clinical Research (Observations, Pathophysiology, and Outcomes) • May 8: Mini-Symposium - Innate Immunity, Inflammation & Microbiology • May 9: Plenary Session III • May 9: Julius Stone Lecture • May 9: Clinical Scholars - Infectious Skin Disease • May 9: Mini-Symposium - Adaptive Immunity & Vaccination

S Skin Cancer A significant amount of skin cancer research will be presented during this year’s SID meeting. More than a fourth of the abstract submissions relate to all types of skin cancers, and many of the Invited/Named Lectures relate to emergent areas of cutaneous .

Track Components: • May 6: Translational Symposium, ‘Immune Therapies for Skin Cancer’ • May 7: Plenary Session I • May 7: Mini-Symposium - Carcinogenesis & Cancer Genetics • May 7: Mini-Symposium - Gene Therapy & Clinical Therapeutics • May 8: Stephen Rothman Memorial Award • May 8: Herman Beerman Lecture • May 8: Mini-Symposium - Clinical Research (Observations, Pathophysiology, and Outcomes) • May 8: Mini-Symposium - Pigmentation & Melanoma • May 8: Interdisciplinary Spotlight: Skin Cancer • May 9: William Montagna Lecture

7 2015 SID RESIDENT RETREAT 2015 SID Albert M. Kligman ATTENDEES Travel Fellowship Awardees Zelma Chiesa, University of Pennsylvania Perelman School of Medicine Lauren Becker, MD, University of Minnesota Vida Chitsazzadeh, MD Anderson Cancer Center Kristin Bibee, MD, PhD, University of Pittsburgh Medical Center Gina DeStefano, Columbia University Yiyin Erin Chen, MD, PhD, University of California, San Francisco Philip Eliades, MGH, Tufts University School of Medicine Albert Sean Chiou, MD, Stanford University Christoph Ellebrecht, University of Pennsylvania William E. Damsky, MD, PhD, Yale University School of Medicine Keitaro Fukuda, Keio University School of Medicine Stephanie Gallitano, MD, SUNY Downstate Mizuho Fukunaga-Kalabis, The Wistar Institute Albert Gutierrez JR., MD, PhD, Mayo Clinic Arizona Sameer Gupta, Massachusetts General , Noori Kim, MD, Johns Hopkins School of Medicine Ali Jabbari, Columbia University Newsha Lajevardi, MD, Warren Alpert Medical School of Brown University Prajakta Jaju, Stanford University Valerie Laniosz, MD, PhD, Mayo Clinic College of Medicine, Rochester Chanisa Kiatsurayanon, Juntendo University Graduate School of Medicine Matthew R. LeBoeuf, MD, PhD, University of Pennsylvania Dong Joo Kim, The Rockefeller University, Stony Brook University Evelyn Lilly, MD, Yale University School of Medicine Tetsuro Kobayashi, Keio University School of Medicine, NCI, NIH Karla I. Martínez Rosales, MD, Universidad Autónoma de Baja California Bradley Kubick, University of AMC William H. McCoy IV, MD, PhD, Washington University School of Medicine Katherine Lewandowski, Northwestern University Chung-Ping Liao, University of Texas Southwestern Medical Center Alexander Means, MD, The Medicine Xinjian Liu, Duke University Rajini Murthy, MD, Emory University Kathryn Martires, New York University School of Medicine Giang-Huong Nguyen, MD, PhD, University of Colorado YC Metzger, Tel Aviv Sourasky Medical Center Khang Nguyen, MD, University of Texas, Southwestern Haley Naik, National Cancer Institute, National Heart, Lung and Blood Institute Ellen Pritchett, MD, Drexel University College of Medicine Audrey Nosbaum, University of California, San Francisco Syril Keena Que, MD, University of Connecticut Health Center Carly Page, Johns Hopkins University Adam Raff, MD, PhD, Sanjay Premi, Yale University School of Medicine Bahram Razani, MD, PhD, University of California, San Francisco Pawinee Rerknimitr, Kyoto University Graduate School of Medicine Chris Richardson, MD, PhD, University of Rochester Adriana Rodríguez-Arámbula, Hospital Central "Dr. Ignacio Morones Prieto", Todd Rickett, MD, Rush University Universidad Autónoma de San Luis Potosí Rachel Rosenstein, MD, PhD, New York University, Langone Medical Center James Sanford, University of California, San Diego Sandeep Saluja, MD, University of Utah Martina Sanlorenzo, University of California, San Francisco Michael Sargen, MD, Emory University Lindsey Seldin, Duke University David Schairer, MD, Einstein-Montefiore Raghav Tripathi, Case Western Reserve University Jeffrey Scott, MD, University , Case Medical Center Stephen Watt, University of Dundee Susan Seo, MD, Roger Williams Medical Center Hua Zhou, University of Maryland Medical School Arsalan Shabbir, MD, PhD, University of Miami Elisha Singer, MD, Northwestern University 2015 SID Student Research / Pooja Sodha, MD, Medstar Washington Karl William Staser, MD, PhD, Washington University School of Medicine Fellow Travel Awardees Andrea Suarez, MD, PhD, Weill Cornell Medical College/New York Presbyterian Hospital Velina Atanasova, Thomas Jefferson University Aparna Bhaduri, Stanford University Jennifer C. Tang, MD, Marshfield Clinic Brandon Cohen, New York University Langone Medical Center Rebecca Vasquez, MD, University of Texas, Southwestern Annie Collier, Indiana University School of Medicine Matthew Vesely, MD, PhD, Yale University School of Medicine Duncan Hieu Dam, Northwestern University Annie Wang, MD, Warren Alpert Medical School of Brown University Liza Gill, Michigan State University Sarah Whitley, MD, PhD, University of Pittsburgh Medical Center Alex Han, Brown University Howa Yeung, MD, Emory University Yu-Ying He, University of Chicago Shali Zhang, MD, Emory University Sho Hiroyasu, Washington State University Xiaolong (Alan) Zhou, MD, MSc, University of Miami Joanna Jackow, Inserm UMR 1163 and Imagine Institute of Genetic Diseases Dongwon Kim, Johns Hopkins School of Medicine Young Lim, Yale School of Medicine 2015 SID PHD RETREAT ATTENDEES Lin Lin, University of North Carolina Nathan Archer, PhD, Johns Hopkins School of Medicine Whitney Longmate, Albany Medical College Xiaomin Bao, PhD, Stanford University Ji Won Oh, University of California, Irvine Joshua Broussard, PhD, Northwestern University Gabriela Petrof, King's College London Brett Roberts, University of Nebraska Medical Center Jing Chen, PhD, University of Pennsylvania Mrinal Sarkar, University of Michigan Natalie Chernets, PhD, Thomas Jefferson University Amanda Suggs, Case Western Reserve University Ann E. Collier, PhD, Indiana University Eddy Wang, University of British Columbia Duncan Hieu M Dam, PhD, Northwestern University Andrew Word, University of Texas-Southwestern Guillermo C. Rivera González, PhD, Yale University School of Medicine Hsin-Jung Wu, Indiana University Geoffrey Hannigan, PhD (2015 Candidate), University of Pennsylvania Xuesong Wu, Medical College of Wisconsin Joanna Jacków, PhD, Laboratory of Genetic Skin Diseases, Imagine Institute, France Xianyong Yin, Anhui Medical University Kindra Kelly-Scumpia, PhD, University of California, Los Angeles Dongwon Kim, PhD, Johns Hopkins School of Medicine Tetsuro Kobayashi, DVM, PhD, National Cancer Institute, National Institutes of Health SID / APSA COLLABORATION Samantha Yu-Jean Lin, PhD, Yale University School of Medicine TRAVEL AWARDEES Alon Mantel, PhD, Hampton University, Skin of Color Research Institute Joseph Cho, University of Utah Tiago Reis Matos, MD, MSc, Harvard Medical School / Dana-Farber Cancer Institute Sakeen Kashem, University of Minnesota Terry Medler, PhD, Oregon Health and Science University Goran Micevic, Yale School of Medicine Haris Mirza, MD, PhD, Yale University School of Medicine Christopher Nirschl, PhD, Brigham and Women's Hospital John T. O'Malley, MD, PhD, Harvard Medical School / Brigham and Women's Hospital 2015 JSID / SID YOUNG Mrinal Kumar Sarkar, PhD, University of Michigan COLLEGIALITY AWARDEES Asuka Suto, DVM, Hokkaido University Graduate School of Medicine Yutaka Inaba, Wakayama Medical University Thirthar Palanivelu Vetrichevvel, MD, University of Western Australia Asuka Suto, Hokkaido University Takeshi Yamauchi, Tohoku University

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Elements area H Lounge

Southern FedEx Elements business Restaurant center Market Second Floor Place MAIN Retail meeting facilitiesENTRANCE

COURTLAND STREET Crystal Ballroom Capacities Room Dimensions L x W Square Feet* Ceiling Height Theater Banquet Reception Conference Board Crystal Ballroom 76’ x 55’ 4,180 12’10” 400 340 400 N/A Crystal A 26’ x 28’ 725 12’10” 75 50 75 25 Crystal B 26’ x 19’ 494 12’10” 50 30 50 15 Crystal C 26’EXIT x 28’ EXIT725 12’10” 75 50 SALON75 EAST25 Crystal D 29’ x 28’ 812 12’10” 80 50 80 30 Crystal E 29’ x 19’ 551 12’10” 55 40 55 20 EAST BALLROOM B C Crystal F 29’ x 28’ 812 12’10” escalator80 50 A 80 30 Crystal AB 26’ x 47’ 1,219 12’10” 125 80 125 40 Crystal ABC 26’B x 75’ A 1,944 12’10” 200 130 SALON200 65 Crystal AF 55’ x 28’ 1,537 12’10” 155 110 155 55 Crystal ABEF 47’ x 55’ 2,582 12’10” 260 180 260 100 Crystal BC GRAND47’ x 26’ BALLROOM1,219 12’10” 125 80 125 40 Second Floor Crystal BE 55’ x 19’ 1,045 12’10” 110 70 E 105 D35 Crystal BCDE 52’ x 56’ 2,582 12’10” 260 180 260 100 Crystal CD 55’ x 28’ 1,537 12’10” 155 110 SALON155 WEST 55 Ballroom Foyer 103’ C x 56’ D2,246 N/A N/A N/A N/A N/A Executive Boardroom 27’ x 32’ 864 M 8’ Pre-FunctionN/A N/A N/A N/A 16** WEST BALLROOM W * THE SQUARE FEET NUMBERS ARE BASED ON USABLE SQUARE FOOTAGE. CAPACITIES TAKE INTO CONSIDERATION PLACEMENT OF BARS, COCKTAIL ROUNDS, FOOD STATIONS AND EXPERIENCE OF THE HOTEL. ** PERMANENT BOARD TABLE. elevators

elevators Open 201 WINDOWS To 202 214 Lobby 213 WINDOWS 212 203 208 207 209 206 WINDOWS 210 205 WINDOWS WINDOWS 211 204 WINDOWS

WINDOWS

SKYBRIDGE PEDESTRIAN

9 Third Floor meeting facilities

305 306 Tennis Courts 304 307 303 308 302 W M Third Floor 301 Pool

elevators

elevators Center 315 W Open M To WINDOWS Lobby 314 313

CONFERENCE CENTER 309 310 311 312 WINDOWS

Galleria Exhibit/Poster Hall

656 - 696 Skin & Hair 575 - 611 Photobiology Developmental Biology

697 - 736 471 - 502 503 - 574 Innate Immunity, Growth Factors Tissue Regeneration 612 - 655 Pigmentation Inflammation & Microbiology Adhesion & Matrix Biology and Wound Healing & Melanoma

429 - 470 Genetic Disease & Gene Regulation Late Breaking 405 - 428 Gene Therapy & Clinical Therapeutics 335 - 404 Epidermal Structure & Barrier Function

001 - 048 LOBBY Adaptive Immunity & Vaccination

102 103 111 112 283 - 334 Epidemiology 101 104 110 113

100 105 106 107 108 109 114

158 - 282 Clinical Research 049 - 095 Auto-Immunity 096 - 157 Carcinogenesis & Cancer Genetics (Observations, Pathophysiology & Outcome)

10 Placement Services Meeting Information & Policies The SID is pleased to offer a placement service to its members. A year-round placement/job postings page is available to members on the SID website at www.sidnet.org. In addition, prospective Reproduction and Photography Policy employers and candidates may conduct interviews or post Any photography, filming, taping, recording or reproduction in additional announcements at the Meeting. A poster board will any medium of any of the programs, exhibits, or lectures (oral or be available in the registration area for such postings. posters) presented at the 2015 SID Annual Meeting is strictly forbidden. Failure to comply with this rule may lead to the removal of your Meeting credentials. Technical Exhibits Exhibits will be on display during the following times in the Galleria Exhibit Hall – Lower Level of the Hilton Atlanta Hotel: On-site Registration On-site registration will take place at the SID Registration thursday, May 7, 2015 10:00 am – 12:00 pm Counter in the Convention Registration Area on the first floor Friday, May 8, 2015 11:15 am – 1:15 pm during the following hours: Saturday, May 9, 2015 10:00 am – 12:00 pm

Wednesday, May 6, 2015 8:00 am - 6:30 pm The SID welcomes representatives from the following thursday, May 7, 2015 7:30 am - 5:00 pm organizations: Friday, May 8, 2015 7:30 am - 4:00 pm Saturday, May 9, 2015 7:30 am - 12:00 pm Cell n Tec

Badges CYTOO Badges for both pre- and on-site registration can be picked up at the SID Registration Counter (First Floor registration area of the Elsevier Hilton Atlanta Hotel). Meeting attendees are required to wear their badges at all times for entry to all sessions and other Metabolon, Inc. Meeting activities. niAMS Special Services for the Physically Challenged Pfizer The Atlanta Hilton Hotel’s facilities are fully accessible to the physically challenged. ZenBio, Inc.

If you have any special needs, please stop at the SID Registration Counter upon arrival or call 404.572.6473 by Thursday, April 30, 2015.

TABLETOP EXHIBITORS Stop by our “Coalition of Skin Diseases” tabletop exhibitors located outside of registration!

American Acne and Rosacea Society https://acneandrosacea.org/

national Alopecia Areata Foundation (NAAF) https://www.naaf.org/

National Eczema Association http://nationaleczema.org/

emory Science Advocacy Network (EScAN) https://www.facebook.com/PolitScientists

11 Wednesday, May 6

Wednesday Sessions

PAGE TITLE 12 Meeting–at-a–Glance

13-14 translational Science Symposium on Immune therapies in Skin Cancer

15 irvin H. Blank Forum

16 State-of-the-Art Plenary Lecture 1

17 State-of-the-Art Plenary Lecture 2

President’s Welcome

18 Albert M. Kligman/Philip Frost Leadership Lecture

19 American Skin Association (ASA) Achievement Awards

20 ASA / David Martin Carter Award

21 Welcome Reception

ASSOCIATE Meeting-At-A-Glance MEETINGS

Wednesday, May 6, 2015 Wednesday, May 6, 2015 ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– International Pachyonychia Congenita International Pachyonychia Congenita 7:15 am – 12:00 pm Consortium (IPCC) Symposium Consortium (IPCC) Symposium 7:15 am – 12:00 pm Salon C, Hilton Atlanta Salon C, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Dermatology Resident Retreat for 7:00 am – 3:00 pm Dermatology Resident Retreat for Future Future Academicians Academicians Salon D, Hilton Atlanta By Invitation Only 7:00 am – 3:00 pm ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Salon D, Hilton Atlanta PhD Retreat for Future Investigators 7:00 am – 3:00 pm By Invitation only Salon E, Hilton Atlanta By Invitation Only ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– PhD Retreat for Future Investigators 7:00 am – 3:00 pm SID Board of Directors Meeting 7:00 am – 2:00 pm Salon E, Hilton Atlanta Crystal Ballroom, Hilton Atlanta By Invitation only ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Registration 8:00 am – 6:30 pm SID Board of Director’s Meeting Convention Registration Area, First Floor, Hilton Atlanta 7:00 am – 2:00 pm ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Crystal Ballroom, Hilton Atlanta Translational Science Symposium: 12:00 pm – 3:00 pm Immune Therapies in Skin Cancer Grand Ballroom, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Irvin H. Blank Forum 3:00 pm – 5:00 pm Getting Under Your Skin: Collaboration with Biomedical Engineers NOTES Grand Ballroom, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– State-of-the-Art Plenary Lecture 1 5:00 pm - 5:30 pm ______Basic Mechanisms and Dynamics of Skin Regeneration ______Valentina Greco, PhD ______Grand Ballroom, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– ______State-of-the-Art Plenary Lecture 2 5:30 pm - 6:00 pm ______Two Sides of a Coin: Hair Keratins in Teeth Maria I. Morasso, PhD ______Grand Ballroom, Hilton Atlanta ______––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– President’s Welcome 6:00 pm -6:15 pm ______S. Wright Caughman, MD ______––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Kligman/Frost Leadership Lecture 6:15 pm - 6:45 pm ______The Importance of Sticking Together ______Kathleen J. Green, PhD ______Grand Ballroom, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– ______American Skin Association (ASA) Achievement 6:45 pm – 6:55 pm ______Awards Grand Ballroom, Hilton Atlanta ______––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– ______ASA/David Martin Carter Award 6:55 pm -7:00 pm Grand Ballroom, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Welcome Reception 7:00 pm – 9:00 pm Pool/Tennis Deck 3rd Floor (weather permitting) or Grand Ballroom/Salon Foyer Location

12 Open to all meeting attendees CME Credit: 3 NOTES Translational Science Symposium ______Immune Therapies in Skin Cancer ______Wednesday, May 6, 2015 12:00 pm – 3:00 pm Grand Ballroom, Hilton Atlanta ______

______12:00 pm introduction ______Oscar Colegio, MD/PhD

______Dr. Colegio, MD/PhD, is an Assistant Professor of Dermatology at Yale School of Medicine where his clinical practice and research is focused on immunodeficiency- ______associated skin cancers and skin disorders associated with solid organ transplantation. ______He directs the Yale Transplant Dermatology Clinic at the Yale-New Haven Transplanta- tion Center, a clinic where care is provided to kidney, liver, heart, pancreas, lung and ______bone marrow transplant recipients. Dr. Colegio’s research focuses on defining the role of immune cells called macrophages in tumor progression. His studies have characterized pathways of tumorigenesis critical to a vari- ______ety of tumor types including melanoma and cutaneous squamous cell carcinoma. Dr. Colegio is a graduate of The University of Texas at Austin, where he earned a B.S. in Pharmacy in 1995, and of Yale University where he ______earned a Ph.D. in Cell Biology in 2003 and an M.D., with election to Alpha Omega Alpha, in 2004. ______12:10 pm Melanoma ______Mario Sznol, MD ______Immune Checkpoint Inhibitors for Treatment of Metastatic Melanoma

______Dr. Sznol received his undergraduate degree from Rice University and Baylor College of Medicine (BCM) in Houston, Texas. He trained in internal medicine at BCM and ______completed a medical oncology fellowship in the Department of Neoplastic Diseases, ______Mount Sinai Hospital, New York. He spent the next twelve years in the Biologics Evalu- ation Section (BES), Investigational Drug Branch (IDB), Cancer Therapy Evaluation Program of the National ______Cancer Institute, and was Head of the BES from 1994-1999. He attended in the Biological Response Modifiers Program, NCI, from 1988-1996 and on the Immunotherapy Service of the Surgery Branch, NCI, from 1997- ______1999. From 1999 to 2004 Dr. Sznol was a Vice President and Executive Officer of Vion Pharmaceuticals in New Haven, CT. Dr. Sznol is currently Professor of Internal Medicine at Yale University School of Medicine ______and is Deputy Section Chief of Medical Oncology, Co-Director of the Melanoma Program, and Co-Director of ______Yale SPORE in Skin Cancer. ______12:40 pm Melanoma ______Paul Tumeh, MD Unique Cellular Signatures (CD8, PD1, PDL1, Clonality) in the ______Tumor Microenvironment Predict Response to Anti-PD1 Therapy ______in Melanoma ______Dr. Paul Tumeh is currently an Assistant Professor in the Division of Dermatology at ______UCLA. He has an active melanoma specialty clinic and serves as a sub-principle investigator on all melanoma immunotherapy clinical trials at UCLA Medical Center. His translational research ______program has two main objectives: i) to identify niches (i.e., discrete cellular microenvironments) within tumors that drive or inhibit response to therapies that block the PD1/PDL1 axis, and ii) to isolate distinct cell-types ______(e.g., myeloid-derived cells) from their native microenvironment in order to investigate the molecular mecha- ______nisms underlying response and non-response to anti-PD-1 therapy. He is currently focused on understanding the phenotype and function of PD-L1+ myeloid-derived cells at the invasive tumor margin and how these ______cells may determine treatment outcome. His most recent publications include articles in Nature, New England Journal of Medicine, and Clinical Cancer Research. ______12:50 pm Melanoma & Cutaneous T-cell lymphoma Rachael Clark, MD/PhD ______Recognizing and Reversing Immune Evasion Strategies ______in Skin Cancer

______Dr. Clark is a physician scientist, a human immunologist, and an Associate Professor ______of Dermatology at Brigham and Women’s Hospital and Harvard Medical School. Her research focuses on the study of T cell responses in skin and other peripheral tissues, ______including T cell responses in healthy skin, impaired T cell responses in skin cancer, and maladaptive T cell activation in inflammatory skin diseases and cutaneous lymphomas. Her studies, carried out on human cells and tissues, have the goals of developing novel therapies for skin disease while at the same time advancing our understanding of human immune responses. 13 ASSOCIATE MEETINGS 1:10 pm cutaneous T-cell lymphoma Richard Edelson, MD Immunizing Against Patient-Specific CTCL Antigens Wednesday, May 6, 2015

Dr. Edelson is the Aaron and Marguerite Lerner Professor and Chairman of the Depart- International Pachyonychia Congenita ment of Dermatology. A graduate of Hamilton College and Yale Medical School, he was a medical intern at the University of Chicago, a Dermatology resident at Harvard Consortium (IPCC) Symposium and an post-doctoral fellow at the National Cancer Institute. He has 7:15 am – 12:00 pm been Yale Dermatology Chairman since 1986, and has also served as Deputy Dean for Salon C, Hilton Atlanta Clinical Affairs and Director of the Yale Comprehensive Cancer Center. Dermatology Resident Retreat for Future 1:30 pm cutaneous T-cell lymphoma Academicians Thomas Kupper , MD 7:00 am – 3:00 pm Salon D, Hilton Atlanta New Insights Into CTCL By Invitation only

Dr. Kupper is the Fitzpatrick Professor of Dermatology at Harvard Medical School, the Chairman of the Departments of Dermatology at Brigham and Women's Hospital and PhD Retreat for Future Investigators the Dana Farber Cancer Institute, and the Director of the Cutaneous Oncology Pro- 7:00 am – 3:00 pm gram at the Dana Farber Brigham and Women's Cancer Center. He received his BS at UCLA, and his MD Salon E, Hilton Atlanta at Yale Medical School, where he trained as a resident and fellow in Surgery and Dermatology. Dr. Kupper By Invitation only has a long track record of outstanding research accomplishments and extramural funding. He serves as an Associate Editor for several journals, including the Journal of Clinical Investigation, and has chaired and SID Board of Director’s Meeting participated in multiple NIH study sections. Dr. Kupper’s research has focused on cellular and molecular 7:00 am – 2:00 pm mechanisms in innate and adaptive immunity, focusing on cytokines, dendritic cells, and T cells, and Crystal Ballroom, Hilton Atlanta includes the study of inflammatory diseases of skin and other epithelial tissues, vaccine development and bioterrorism, wound healing, and cancers of the skin and lymphoid organs, including translational research in cutaneous lymphomas and melanoma.

1:50 pm Merkel cell carcinoma Paul Nghiem, MD/PhD Merkel polyomavirus and rationale for immunotherapy in Merkel NOTES cell carcinoma

Dr. Nghiem is the Michael Piepkorn {pronounced pip-corn} Endowed Chair in Der- ______matology Research and a Professor of Dermatology and at the University ______of Washington and the Fred Hutchinson Cancer Research Center in Seattle. He grew up in Olympia, Washington, and attended college at Harvard University.He then pursued MD and PhD ______degrees at Stanford University where he studied Cancer Biology and Immunology. ______2:10 pm Merkel cell carcinoma ______Isaac Brownell, MD/PhD Immunotherapy Trials for Merkel cell carcinoma ______Dr. Brownell is a Board Certified Dermatologist and a Fellow of the American Acad- emy of Dermatology. He obtained degrees in electrical engineering and mathematics ______prior to undergoing MD/PhD training at Baylor College of Medicine. Dr. Brownell completed a dermatology residency at the New York University School of Medicine, ______and a postdoctoral research fellowship the laboratory of Dr. Alexandra Joyner at the Sloan-Kettering ______Institute. On the clinical faculty at the Memorial Sloan-Kettering Cancer Center, his practice focused on patients with high-risk skin cancers. In 2011, Dr. Brownell joined the Dermatology Branch in the Center ______for Cancer Research, National Cancer Institute where he is Head of the Cutaneous Development and Carcinogenesis Section. ______2:20 pm squamous cell carcinoma Sarah Aaron, MD/PhD ______Infection and Immunity in Cutaneous Squamous Cell Carcinoma ______

Dr. Aaron is Assistant Professor in residence of dermatology at the University of ______California, San Francisco (UCSF) and the Helen Diller Family Comprehensive Cancer Center (HDFCC). She is Director of the High Risk Skin Cancer Program, Director of the Dermatology Clinical Research Unit and the Associate Director of the Dermatolog- ic Surgery and Laser Center at UCSF. She is also Chief of Mohs Micrographic Surgery at the San Francisco VA Medical Center and is affiliated with the Melanoma Center in San Francisco.

2:30 pm closing Panel

14 Open to all meeting attendees CME Credit: 2 NOTES Irvin H. Blank Forum ______Getting Under Your Skin: Collaboration with Biomedical Engineers ______Wednesday, May 6, 2015 3:00 pm – 5:00 pm Grand Ballroom, Hilton Atlanta ______3:00 pm Introduction ______Andrew Kowalczyk, PhD ______Dr. Kowalczyk is a faculty member at Emory University in the departments of Cell Biol- ______ogy and Dermatology. Research in the Kowalczyk laboratory addresses fundamental mechanisms of cell-cell contact in the context of epidermal blistering diseases, and in ______vascular development and angiogenesis. Dr. Kowalczyk’s current work centers on the ______regulation of plasma membrane dynamics of members of the cadherin family of cell adhesion molecules, and the roles of these proteins in the mechanical integrity of the ______epidermis and other tissues.

______3:05 pm Technologies & Skin John Rogers, PhD ______Dr. Rogers obtained BA and BS degrees in chemistry and in physics from the University of Texas, Austin, in 1989. From MIT, he received SM degrees in physics and in ______chemistry in 1992 and the PhD degree in physical chemistry in 1995. From 1995 to 1997, Rogers was a Junior Fellow in the Harvard University Society of Fellows. He ______joined Bell Laboratories as a Member of Technical Staff in the Condensed Matter Phys- ics Research Department in 1997, and served as Director of this department from the ______end of 2000 to 2002. He is currently Swanlund Chair Professor at University of Illinois at Urbana/Champaign, ______with a primary appointment in the Department of Materials Science and Engineering, and joint appointments in several other departments, including Bioengineering. He is Director of the Seitz Materials Research ______Laboratory.

______3:30 pm Mechanical Engineering & Skin Valerie Horsley, PhD ______Dr. Horsley grew up in the Atlanta area and went to Furman University for her undergraduate work. She received her Ph.D. from Emory University in 2003 where ______she studied muscle regeneration with Grace Pavlath. Dr. Horsley did her postdoctoral work in Elaine Fuchs’ laboratory and joined Yale’s faculty in 2009 in the department of ______Molecular, Cellular and Developmental Biology. She is currently an associate professor and a member of the Dermatology department, the Yale Stem Cell Center and Yale ______Cancer Center. ______3:55 pm Micro-needles, Devices & The Skin ______Mark Prausnitz, PhD

______Dr. Prausnitz earned his B.S. from Stanford University and his PhD from the Massachu- setts Institute of Technology. In collaboration with Emory University, the Centers for Dis- ______ease Control and Prevention and other organizations, Dr. Prausnitz’s group is advancing ______microneedles from device design and fabrication through pharmaceutical formulation and pre-clinical animal studies through studies in human subjects. In addition to ______developing a self-administered influenza vaccine using microneedles, Dr. Prausnitz is translating microneedles technology especially to make vaccination in developing countries more effective. ______4:20 pm Biomaterials & Tissues ______Themis Kyriakides, PhD

______Dr. Kyriakides received his B.Sc. and Ph.D. from Washington State University. In 1997, ______Dr. Kyriakides joined the University of Washington Engineered Biomaterials ERC, a NSF-funded center and held the position of Acting Instructor and Research Assistant ______Professor. In 2004, Dr. Kyriakides joined Yale University as a member of the Vascular Bi- ology Program with appointments in Pathology and Biomedical Engineering. Currently, ______he holds the rank of Associate Professor and has split appointment between Pathology ______and Biomedical Engineering. His current research is primarily focused on cell-matrix and cell-biomaterial interactions in the foreign body response and wound healing. ______4:45 pm Wrap-Up ______Andrew Kowalczyk, PhD

15 Open to all meeting attendees CME Credit: .5 ASSOCIATE MEETINGS State-of-the-Art Plenary Lecture 1 Basic Mechanisms and Dynamics of Skin Regeneration Wednesday, May 6, 2015

International Pachyonychia Congenita Consortium (IPCC) Symposium Wednesday, May 6, 2015 5:00 pm – 5:30 pm Grand Ballroom, Hilton Atlanta 7:15 am – 12:00 pm Salon C, Hilton Atlanta

Dermatology Resident Retreat for Future Introduction by: Paul Nghiem, MD/PhD Academicians 7:00 am – 3:00 pm Valentina Greco, PhD Salon D, Hilton Atlanta Yale University By Invitation only New Haven, CT

Dr. Greco was born in Palermo, Italy. She did her undergraduate in Molecular Biology at the PhD Retreat for Future Investigators University of Palermo, Italy. Valentina did her PhD with Suzanne Eaton at the EMBL / 7:00 am – 3:00 pm MPI-CBG (Germany) (1998-2002) and a post-doc with Elaine Fuchs at the Rockefeller Salon E, Hilton Atlanta University (2003-2009). Dr. Greco is currently an Assistant Professor in the Genetics and By Invitation only Dermatology Department, and a member of the Yale Stem Cell Center and Yale Cancer Center at Yale University (2009-present). SID Board of Director’s Meeting 7:00 am – 2:00 pm Crystal Ballroom, Hilton Atlanta

NOTES ______NOTES

______

16 Open to all meeting attendees CME Credit: .5 NOTES State-of-the-Art Plenary Lecture 2 ______Two Sides of a Coin: Hair Keratins in Teeth ______Wednesday, May 6, 2015 5:30 pm – 6:00 pm Grand Ballroom, Hilton Atlanta ______Introduction by: Victoria Werth, MD

______Maria I. Morasso, PhD NIH, NIAMS ______Bethesda, MD ______Dr. Morasso received her PhD in Biochemistry from the Venezuelan Institute of ______Scientific Investigations (IVIC). She started at the NIH as a post-doctoral fellow in the laboratory of Dr. Thomas Sargent in NICHD. In May 2000, she became a tenure-track ______investigator and headed the Developmental Skin Biology Unit. Since May 2008, Dr. Morasso is the Chief of the Developmental Skin Biology Section and the Laboratory of Skin Biology. ______She also serves as an adjunct investigator in the Center for Cancer Research, NCI. ______NOTES ______

17 Open to all meeting attendees CME Credit: .5 ASSOCIATE MEETINGS Albert M. Kligman / Phillip Frost Leadership Lecture Wednesday, May 6, 2015 The Importance of Sticking Together International Pachyonychia Congenita Consortium (IPCC) Symposium 7:15 am – 12:00 pm Wednesday, May 6, 2015 6:15 pm – 6:45 pm Grand Ballroom, Hilton Atlanta Salon C, Hilton Atlanta

Dermatology Resident Retreat for Future Academicians 7:00 am – 3:00 pm Salon D, Hilton Atlanta Introduction by: S. Wright Caughman, MD By Invitation only Kathleen J. Green, PhD Northwestern University PhD Retreat for Future Investigators Chicago, Illinois 7:00 am – 3:00 pm Salon E, Hilton Atlanta Dr. Kathleen Green is the Joseph L. Mayberry Professor of Pathology and Professor of Derma- By Invitation only tology at Northwestern University Feinberg School of Medicine. Following her graduation with honors in Biology from Pomona College in Claremont California, Dr. Green obtained SID Board of Director’s Meeting Ph.D. training in Cell and Developmental Biology at Washington University in St. Louis. She 7:00 am – 2:00 pm moved to Chicago to do postdoctoral research in Cell Biology at Northwestern University and Crystal Ballroom, Hilton Atlanta joined the Pathology faculty in 1987. The Green laboratory has a longstanding interest and expertise in defining functions of the cadherin family of adhesion receptors in development and differentiation, particularly of the epidermis. These molecules and their associated pro- teins assemble into intercellular junctions where they play critical roles in mediating cell-cell adhesion. Beyond their structural roles, cadherins mediate cross talk with signaling pathways including growth factor receptor tyrosine kinases to regulate tissue morphogenesis, differentia- tion and pathogenesis. Her work was instrumental in the discovery of the plakin gene family, members which link the cytoskeleton to cell junctions, and facilitated the identification of hu- NOTES man diseases resulting from mutations in desmoplakin. Dr. Green is active in the leadership of several scientific societies and recently served as President of the Society for Investigative Dermatology. She is currently Secretary of the American Society for Cell Biology. In addition ______to having been a member and Chair of multiple peer review committees, Dr. Green served on the Advisory Council for the National Institute of Arthritis, Musculoskeletal and Skin Disease ______from 2007-10. She is consulting Editor for the Journal of Clinical Investigation, Associate ______Editor for the Journal of Investigative Dermatology and Deputy Editor in Chief of the Journal of Cell Science. ______

LECTURESHIP HISTORY ______Established in 2007 by Dr. Phillip Frost, the lectureship is intended to honor Dr. Albert M. Klig- ______man, whose great commitment to dermatology and numerous contributions to the specialty has inspired generations of researchers and practitioners. The award is made to an individual in ac- ______knowledgment of significant contributions in the past five years to the understanding of structure and function of skin. ______

18 Open to all meeting attendees CME Credit: 0 NOTES American Skin Association (ASA) ______Research Achievement Awards ______Wednesday, May 6, 2015 6:45 pm – 6:55 pm Grand Ballroom, Hilton Atlanta ______Instituted in 1989 to identify established scientists in investigative dermatology and cutaneous biology, ______ASA’s Research Achievement Awards recognize those who have greatly advanced work related to auto- immune and inflammatory skin diseases, melanoma and non-melanoma skin cancer, psoriasis, public ______policy and medical education, and vitiligo and pigment cell disorders. ______American Skin Association is delighted to present its 2015 Research Achievement Awards to: ______

______Mark C. Udey, MD/PhD National Cancer Institute ______Autoimmune and Inflammatory Skin Disorders Research ______Alain H. Rook, MD ______University of Pennsylvania Melanoma and Skin Cancer Research ______David J. Margolis, MD/PhD ______University of Pennsylvania Psoriasis Research ______Mayumi Ito, PhD New York University ______Vitiligo and Pigment Cell Biology Research

______Alexa Boer Kimball, MD/MPH Massachusetts General Hospital ______Public Policy and Medical Education ______

19 Open to all meeting attendees CME Credit: 0 ASSOCIATE MEETINGS ASA/David Martin Carter Mentor Award Wednesday, May 6, 2015

International Pachyonychia Congenita Consortium (IPCC) Symposium Wednesday, May 6, 2015 6:55 pm – 7:00 pm Grand Ballroom, Hilton Atlanta 7:15 am – 12:00 pm Salon C, Hilton Atlanta

ASA’s David Martin Carter Mentor Award honors a member of the dermatology community who Dermatology Resident Retreat for Future embodies the characteristics of the late David Martin Carter, MD, PhD that made him an inspiration to Academicians many dermatologists/investigators, colleagues and medical students throughout the world. 7:00 am – 3:00 pm Salon D, Hilton Atlanta By Invitation only American Skin Association is delighted to present its 2015 David Martin Carter Mentor Award to:

PhD Retreat for Future Investigators Howard P. Baden, MD 7:00 am – 3:00 pm Massachusetts General Hospital Salon E, Hilton Atlanta By Invitation only

SID Board of Director’s Meeting 7:00 am – 2:00 pm Crystal Ballroom, Hilton Atlanta

NOTES

______

20 Open to all meeting attendees CME Credit: 0 NOTES Welcome Reception ______Wednesday, May 6, 2015 7:00 pm – 9:00 pm Pool/Tennis Deck 3rd Floor (weather permitting) or ______G grand Ballroom/Salon Foyers, H hilton Atlanta ______Join us for a Welcome Reception to kick off the 2015 SID Annual Meeting! ______All attendees are invited, free of charge, to gather for drinks and hors d’oeuvres and mingle with colleagues at the Pool/Tennis Deck on the third floor immediately following the last session of ______the evening. In the event of inclement weather, the reception will be held in the Grand Ballroom/Salon ______Foyers. ______(Beverage tokens will be distributed in meeting registration packets.). ______

21 Thursday Sessions

PAGE TITLE 22 Meeting-at-a-Glance

23 Pediatric Dermatology Research Alliance/Society for Pediatric Dermatology Session

24 Plenary Session 1 T hursday, May 7 25 Eugene M. Farber Lecture

26 naomi M. Kanof Lecture

27 Clinical Scholars Program Session 1

28 Satellite Symposium: Academic-Industry Partnership Project (AIPP)

29 American DermatoEpidemiology Network (ADEN) Meeting

30 American Acne and Rosacea Society (AARS) Scientific 4th Annual Scientific Symposium

national Rosacea Society Research (NSRS) Workshop

31 international Society for Cutaneous Lymphomas / Cutaneous T-Cell lymphoma (ISCL/CTCL) Symposium

32 Concurrent Mini-Symposium 1: Auto Immunity

33 Concurrent Mini-Symposium 2: Carcinogenesis & Cancer Genetics

34 Concurrent Mini-Symposium 3: Epidemiology

35 Concurrent Mini-Symposium 4: Gene Therapy & Clinical Therapeutics

36 Concurrent Mini-Symposium 5: Skin & Hair Developmental Biology

37 Mini-Symposia Mixers

38 Social Event

ASSOCIATE Meeting-At-A-Glance MEETINGS Thursday, May 7, 2015 ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Pediatric Dermatology Research Alliance/ 7:00 am – 8:00 am Thursday, May 7, 2015 Society for Pediatric Dermatology Session Rooms 204-207, Hilton Atlanta Pediatric Dermatology Research Alliance/ ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Society for Pediatric Dermatology Session Registration 7:30 am – 5:00 pm Convention Registration Area, First Floor, Hilton Atlanta 7:00 am – 8:00 am ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Room 204-207, Hilton Atlanta Plenary Session I 8:00 am – 9:00 am Grand Ballroom, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– American Dermato-Epidemiology Network Eugene M. Farber Lecture 9:00 am – 9:30 am Symposium (ADEN) A Natural History of Psoriasis 12:00 pm – 1:45 pm Christopher E.M. Griffiths, MD, FRCP, FMedSci Salon C, Hilton Atlanta Grand Ballroom, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Naomi M. Kanof Lecture 9:30 am – 10:00 am American Acne and Rosacea Society (AARS) Silencing the Sézary Cell – Past, Present, & Future Scientific 4th Annual Scientific Symposium Madeleine Duvic, MD 12:00 pm – 1:45 pm Grand Ballroom, Hilton Atlanta Grand Ballroom, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Clinical Scholars Program Session 1 10:00 am – 12:00 pm Academic/Industry Session Co-Morbidities: Skin & Systemic Disease Panel Discussion Grand Ballroom, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– 12:00 pm – 12:45 pm Poster Session I 10:00 am – 12:00 pm Individual Meetings (set up in advance Poster #’s 001-245 Odd & #’s 246-490 Even Galleria Exhibit Hall, Hilton Atlanta by the SID) – Room 203, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– 12:00 pm - 1:45 pm American DermatoEpidemiology Network 12:00 pm - 1:45 pm (ADEN) Meeting International Society for Cutaneous Salon C, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Lymphomas/Cutaneous T-Cell American Acne and Rosacea Society (AARS) 12:00 pm – 1:45 pm Lymphoma Symposium (ISCL/CTCL) Scientific 4th Annual Scientific Symposium 12:00 pm – 2:00 pm Grand Ballroom, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Room 204-207 – Hilton Atlanta Satellite Symposium 12:00 pm – 12:45 pm Academic-Industry Partnership Project National Rosacea Society Research Panel Discussion 12:00 pm - 12:45 pm Workshop Salon A/B, Hilton Atlanta 12:00 pm – 1:45 pm Individual Meetings (set up in advance by the SID) – Room 203, Salon D, Hilton Atlanta Hilton Atlanta 12:00 pm - 1:45 pm ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– National Rosacea Society Research Workshop 12:00 pm – 1:45 pm The National Eczema Association Salon D, Hilton Atlanta Reception– The Decade of Eczema! ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– 5:00 pm – 6:30 pm International Society for Cutaneous 12:00 pm – 2:00 pm Crystal Ballroom, Hilton Atlanta Lymphomas-Cutaneous T-Cell Lymphoma Symposium (ISCL/CTCL) Room 204-207, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Concurrent Mini-Symposia 2:00 pm – 5:00 pm Auto Immunity Salon E, Hilton Atlanta NOTES Carcinogenesis & Cancer Genetics Grand Ballroom, Hilton Atlanta ______Epidemiology Salon C, Hilton Atlanta ______Gene Therapy & Clinical Therapeutics ______Salon A/B, Hilton Atlanta ______Skin & Hair Developmental Biology Salon D, Hilton Atlanta ______––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Mini-Symposia Mixers 5:00 pm – 6:00 pm ______Individual Concurrent Meeting Rooms ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– The National Eczema Association Reception – 5:00 pm – 6:30 pm The Decade of Eczema! Crystal Ballroom, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Social Event 6:30 pm - 10:30 pm Georgia Aquarium ticketed Event: Pre-Registration Required Buses depart from the Hilton Atlanta beginning at 6:00 pm. Buses will begin shuttling guests back to the hotel beginning at 8:30 pm. 22

Open to all meeting attendees CME Credit: 0 NOTES Pediatric Dermatology Research ______Alliance/Society for Pediatric ______Dermatology Session ______Thursday, May 7, 2015 7:00 am - 8:00 am Rooms 204-207, Hilton Atlanta (COFFEE WILL BE SERVED) ______

______7:00 am welcome/Overview I: Pediatric Dermatology at SID ______Megha Tollefson, Mayo Clinic

______7:15 am Special Presentation: Inflammation and Immunity in Skin: ______Learning from Acne Jenny Kim, University of California, Los Angeles ______

______7:40 am Abstract Presentation #036 Pediatric is characterized by increased T-cell activation ______with aberrant T-cell development. Hitokazu Esaki et al. Mt. Sinai School of ______Medicine, New York and Northwestern University, Chicago

______7:50 am - 7:55 am Discussion and Concluding Remarks ______Special thanks to the Pediatric Dermatology Research Alliance and the Society ______for Pediatric Dermatology for supporting these sessions. ______NOTES ______

23 Open to all meeting attendees CME Credit: 1 ASSOCIATE MEETINGS PLENARY SESSION I Presiders: Richard L. Gallo, MD/PhD and Alice Pentland, MD Thursday, May 7, 2015

Pediatric Dermatology Research Alliance/ Thursday, May 7, 2015 8:00 am - 9:00 am Grand Ballroom, Hilton Atlanta Society for Pediatric Dermatology Session 7:00 am – 8:00 am Room 204-207, Hilton Atlanta

1. Functional characterization of AHR promoter polymorphism that contributes to reduced American Dermato-Epidemiology Network vitiligo risk. Xiaowen Wang, Kai Li, Ling Liu, Zhe Jian, Gang Wang, Chunying Li and Tianwen Symposium (ADEN) Gao. Xi’an, China. 8:00 am, Poster #319 12:00 pm – 1:45 pm Salon C, Hilton Atlanta 2. A wave of regulatory T cells into neonatal skin mediates tolerance to commensal microbes. Tiffany C. Scharschmidt, Kimberly S. Vasquez, Hong-An Truong, Sofia V. Gearty, Mariela L. Pauli, American Acne and Rosacea Society (AARS) Audrey Nosbaum, Michael Otto, James J. Moon, Abul K. Abbas, Michael A. Fischbach and Scientific 4th Annual Scientific Symposium Michael D. Rosenblum. San Francisco, CA; Bethesda, MD and Charlestown, MA. 8:12 am, 12:00 pm – 1:45 pm Poster #011 Grand Ballroom, Hilton Atlanta

Academic/Industry Session 3. Desmoglein 3 chimeric autoantibody receptor T cells: A novel strategy for immunotherapy of Panel Discussion pemphigus vulgaris. Christoph Ellebrecht, Michael Jeffrey T. Cho, Xuming Mao, Vijay G. Bhoj, 12:00 pm – 12:45 pm Ching-Yi Tsai, Selene Nunez-Cruz, Michael C. Milone and Aimee S. Payne. Philadelphia, PA. 8:24 am, Poster #059 Individual Meetings (set up in advance by the SID) – Room 203, Hilton Atlanta 4. Cutaneous neoplasms undergo a dynamic immunoediting process. Dennis R. Roop and Bradley 12:00 pm - 1:45 pm J. Kubick. Aurora, CO. 8:36 am, Poster #114 International Society for Cutaneous 5. The microbiome of patients with atopic dermatitis has deficient antimicrobial function. Lymphomas/Cutaneous T-Cell Lymphoma Symposium (ISCL/CTCL) Teruaki Nakatsuji, Tissa Hata, Aimee Two, Kimberly Chun, Paul Kotol, Amina Bouslimani, 12:00 pm – 2:00 pm Haythem Latif, Alexandre Lockhart, Keli Artis, Gloria David, Patricia Taylor, Joanne Strieb, Peter Room 204-207 – Hilton Atlanta Dorrestein, Karsten Zengler, Donald Leung and Richard L. Gallo. San Diego, CA; Chapel Hill, NC and Denver, CO. 8:48 am, Poster #193 National Rosacea Society Research Workshop 12:00 pm – 1:45 pm Salon D, Hilton Atlanta

NOTES The National Eczema Association ______Reception– The Decade of Eczema! 5:00 pm – 6:30 pm ______Crystal Ballroom, Hilton Atlanta ______NOTES ______

24 Open to all meeting attendees CME Credit: .5 NOTES Eugene M. Farber Lecture ______A Natural History of Psoriasis ______Thursday, May 7, 2015 9:00 am - 9:30 am Grand Ballroom, Hilton Atlanta ______

______Introduction by: Nicole L. Ward, PhD ______

______Christopher E.M. Griffiths MD, FRCP, FMedSci ______University of Manchester Manchester, UK ______Lecturer BIO ______Dr. Griffiths gained a 1st Class Hons BSc in Anatomy and qualified in Medicine from ______St Thomas’ Hospital Medical School, London University. He trained in Dermatology at St Mary’s Hospital, London, and at the University of Michigan. He was appointed to the Foundation Chair in ______Dermatology at the University of Manchester in 1994 and is an honorary consultant dermatologist at ______Salford Royal NHS Foundation Trust. At the University of Manchester he has served variously as: Head of Medicine and Neuroscience; Head of the School of Translational Medicine; Research Dean and; ______Director of the Manchester Academic Health Science Centre. ______LECTURESHIP HISTORY ______The Eugene M. Farber endowment was established by the family of Eugene M. ______Farber, MD, who devoted his scientific career to understanding the pathogenesis of psoriasis. In 2007, the SID Board of Directors voted to create the Eugene M. ______Farber Endowed Lecture. It is presented at the Society’s Annual Meeting by an ______investigator whose work is relevant to expanding our insights into the pathophysi- ______ology and treatment of psoriasis. ______NOTES ______

25 Open to all meeting attendees CME Credit: .5 ASSOCIATE MEETINGS Naomi M. Kanof Lecture Silencing the Sézary Cell - Past, Present, and Future Thursday, May 7, 2015

Pediatric Dermatology Research Alliance/ Thursday, May 7, 2015 9:30 am - 10:00 am Grand Ballroom, Hilton Atlanta Society for Pediatric Dermatology Session 7:00 am – 8:00 am Room 204-207, Hilton Atlanta

Introduction by: Mark Udey, MD/PhD American Dermato-Epidemiology Network Symposium (ADEN) 12:00 pm – 1:45 pm Madeleine Duvic, MD Salon C, Hilton Atlanta The University of Texas, MD Anderson Cancer Center American Acne and Rosacea Society (AARS) Houston, TX Scientific 4th Annual Scientific Symposium 12:00 pm – 1:45 pm Grand Ballroom, Hilton Atlanta Lecturer BIO Academic/Industry Session Dr. Duvic is Professor of Internal Medicine and Dermatology and Deputy Chairman Panel Discussion of the Department of Dermatology at The University of Texas, MD Anderson Cancer Center in Houston, 12:00 pm – 12:45 pm Texas. She attended Rice University and Duke University Medical School, completing residencies in internal medicine and dermatology, and fellowships in molecular biology and geriatrics. She joined Individual Meetings (set up in advance the faculty at Duke and University of Texas Medical School and Cancer Center where she established a by the SID) – Room 203, Hilton Atlanta translational molecular biology laboratory and a busy cutaneous lymphoma clinic (CTCL) focused on 12:00 pm - 1:45 pm understanding the pathogenesis and developing new drugs for CTCL. International Society for Cutaneous Lymphomas/Cutaneous T-Cell Lymphoma Symposium (ISCL/CTCL) 12:00 pm – 2:00 pm Room 204-207 – Hilton Atlanta

LECTURESHIP HISTORY National Rosacea Society Research ______Workshop Established in 1988, this award was established to honor the memory of Naomi 12:00 pm – 1:45 pm Kanof, MD. The Naomi M. Kanof Lectureship honors an individual making Salon D, Hilton Atlanta significant contributions to the improvement of health through clinical research. The National Eczema Association Clinical research is broadly defined as any scientific endeavor with a direct ap- Reception– The Decade of Eczema! plication to improving the prevention, diagnosis or treatment of clinical disease. 5:00 pm – 6:30 pm This investigative work can be based in the laboratory and should be implement- Crystal Ballroom, Hilton Atlanta ed or just ready to be implemented in clinical practice.

NOTES ______NOTES ______

26 Open to all meeting attendees CME Credit: 0 NOTES Clinical Scholars Program – ______Session I ______Thursday, May 7, 2015 10:00 am – 12:00 pm Grand Ballroom, Hilton Atlanta ______

______10:00 am Co-Morbidities: Skin and Systemic Disease Overview ______Richard Weller, MD, FRCP ______Dr. Weller is an academic dermatologist at the University of Edinburgh, UK. He trained ______in internal medicine in the UK and Australia, and in dermatology at the St Johns’ Insti- ______tute of Dermatology, London, and in Scotland. Dr. Weller’s research training took place in Edinburgh, Dusseldorf, Germany and Pittsburgh USA. His major research interest is ______on NO mediated biology in the skin and cardiovascular system and how this is affected by UV radiation.

______10:25 am Cutaneous Regulation of Blood Pressure

______Psoriasis severity is increased by alcohol abuse: An animal model of alcohol abuse and psoriasis. Rhonda M. Brand, Melissa Paglia, Louis D. Falo. ______Poster #402, Presented by Rhonda M. Brand, PhD ______10:35 am Q&A ______10:45 am TCR sequencing provides superior diagnosis, staging and clinical assessment of patients ______with cutaneous T cell lymphoma. John Thomas OMalley, Ilan Kirsch, Rei Watanabe, ______David Williamson, Laura Campbell, Chris Elco, Jessica Emberley Teague, Ahmed Gehad, Elizabeth Lowry, James G. Krueger, Harlan Robins, Thomas S. Kupper and Rachael Clark. ______Poster #225, Presented by John T. O’Malley, MD/PhD

______10:55 am Q&A

______11:05 am Salt-sensitive Hypertension: A Skin Disease? ______Jens Titze, MD

______Dr. Titze is an Associate Professor at Vanderbilt University School of Medicine. His ______clinical specialties and interests are Nephrology: General Nephrology. Dr. Titze’s ______education and medical training was at Charité- Universitätsmedizin Berlin. His clinical trials include Tissue Sodium in Pre-hypertensive Patients and Testing Tissue Sodium ______Stores in CAPD Patients—Aims 1 & 2.

______11:20 am Q&A

______11:30 am pAnel Discussion ______Richard Weller, MD, FRCP Jens Titze, MD ______Joel Gelfand, MD, MSCE ______Dr. Gelfand is Associate Professor of Dermatology and Epidemiology (tenured) at the University of Pennsyl- vania’s Perelman School of Medicine. He is principal investigator of three large NIH funded psoriasis projects. ______Dr. Gelfand is the author of over 100 scientific publications (cited over 8000 times, H index 38) which appear in journals such as JAMA, BMJ, European Heart Journal, Annals of , JAMA Dermatology, JAAD, ______and the JID. He is the recipient of the American Skin Association’s Psoriasis Achievement Award, PENN’s Marjorie Bowman Award, and is an elected member of the American Society for Clinical Investigation. He has ______given over 10 named lectureships and keynote addresses including the Society for Investigative Dermatology’s ______Eugene M. Farber lecture. He has received grant support from NIH (F32, K23, RC1, 3 R01’s, K24), FDA (R01), the Dermatology Foundation, the American Skin Association, the National Psoriasis Foundation, and numerous ______pharmaceutical companies to support his independent research program.

______Abrar Qureshi, MD Dr. Qureshi is Chair of the Department of Dermatology at the Warren Alpert Medical School of Brown ______University and Dermatologist-in-Chief at Rhode Island Hospital, The Miriam Hospital and Hasbro Children’s ______Hospital in Providence. His major research interest is in population science, particularly the clinical and molecular epidemiology of skin diseases. Dr. Qureshi’s laboratory encompasses work in epidemiology, ______outcomes research, clinical trials and health services research. On the clinical front, he enjoys working in a multidisciplinary environment closely with his rheumatology colleagues, caring for patients with complex skin and musculoskeletal conditions. Helping care for some of the sickest medical dermatology patients has been an inspiration for his research. 27

Open to all meeting attendees CME Credit: 0 ASSOCIATE MEETINGS Satellite Symposium Academic-Industry Partnership Project (AIPP) Thursday, May 7, 2015

Pediatric Dermatology Research Alliance/ Salon A/B – Panel Session Thursday, May 7, 2015 12:00 pm – 1:45 pm Society for Pediatric Dermatology Session Room 203 – Speed-Dating Session 7:00 am – 8:00 am Room 204-207, Hilton Atlanta

12:00 pm – 12:45 pm Panel Session (open to all registered meeting attendees) American Dermato-Epidemiology Network 12:05 pm – 1:45 pm Speed-Dating Session (pre-registration required) Symposium (ADEN) Individual Meetings (set up in advance by the SID) 12:00 pm – 1:45 pm 12:00 pm Introductions Salon C, Hilton Atlanta Kevin Cooper, MD American Acne and Rosacea Society (AARS) Dr. Kevin D. Cooper is the Professor and Chair of the Department of Dermatology Scientific 4th Annual Scientific Symposium at Case Western Reserve University (CWRU) and University Hospitals Case Medi- 12:00 pm – 1:45 pm cal Center (UHCMC) in Cleveland, Ohio. He directs the NIH NIAMS Skin Diseases Grand Ballroom, Hilton Atlanta Research Center at CWRU and the UHCMC Murdough Family Center for Psoriasis, and directed the first NIAMS Center of Research Translation focused on skin disease. He is Academic/Industry Session co-inventor of the first biologic approved for psoriasis, has taken several lab-based projects into NIH-funded phase I clinical trials, and has participated in multiple industry-based pre-clinical and clinical translational Panel Discussion therapeutic programs. 12:00 pm – 12:45 pm

Individual Meetings (set up in advance 12:05 pm Positive Licensing Experience by the SID) – Room 203, Hilton Atlanta David Woodley, MD 12:00 pm - 1:45 pm

Dr. Woodley completed his undergraduate degree in English Literature at Washington International Society for Cutaneous University in St. Louis and his medical school education at the University of Missouri in Columbia, Missouri. He completed his dermatology residency training at the Lymphomas/Cutaneous T-Cell University of North Carolina in Chapel Hill, North Carolina. Dr. Woodley’s scientific Lymphoma Symposium (ISCL/CTCL) interests include type VII collagen, keratinocyte motility, wound healing, keratinocyte- 12:00 pm – 2:00 pm derived collagenases, autoimmune bullous diseases and hereditary dystrophic epidermolysis bullosa.He is the Room 204-207 – Hilton Atlanta Co-Editor of a book entitled The Biology of Skin with Dr. Ruth Freinkel and serves as an Associate Editor of The Journal of the American Academy of Dermatology, The Archives of Dermatology, Clinical and Experimental National Rosacea Society Research Dermatology and Dermatology. Workshop 12:00 pm – 1:45 pm 12:15 pm Successful Leap to Working in Industry Salon D, Hilton Atlanta Howard Welgus, MD The National Eczema Association Dr. Welgus has been Chief Medical Officer at Thesan Pharmaceuticals for the past Reception– The Decade of Eczema! 2 years. Before this, he served as CMO and VP and Head of R&D at Nycomed U.S. 5:00 pm – 6:30 pm (Fougera / PharmaDerm). In this capacity, he directed the post-approval development Crystal Ballroom, Hilton Atlanta of Solaraze®, Cutivate Lotion®, and Veregen®. Prior to Nycomed U.S., Dr. Welgus was VP and Head of the Inflammation and Dermatology Therapeutic Areas at Pfizer – Ann Arbor. During this time, his Dermatology team placed 10 new compounds into clinical development. He was also involved in developing Lyrica® for fibromyalgia and Xeljanz® for rheumatoid arthritis and psoriasis. The first half of Dr. Welgus’ career was spent in academics where he was Professor of Dermatology at Washington University School of Medicine. During this time, he published over 115 original scientific articles. NOTES

12:25 pm Summary of March 2015 Dermatology ______Entrepreneurship Conference ______William Ju, MD ______Dr. Ju is a board-certified dermatologist and has over 20 years of biopharmaceutical ______experience in a wide variety of therapeutic areas, including dermatology. He is presi- dent and a founding trustee of Advancing Innovation in Dermatology, Inc. He has been ______president and chief executive officer of Follica, Inc. and chief operating officer at PTC Therapeutics, Inc. (PTCT). In addition, he has held executive positions at Pharmacia ______Corporation/Pfizer, Inc. Merck & Co., Inc., and Hoffmann La Roche, Inc. in a broad spectrum of product development functions. Dr. Ju served as project leader for SUTENT®, introduced CANCIDAS® into humans, and was part of the product development teams for CRIXIVAN® and TRANSLARNA™. He obtained his M.D. with Alpha Omega Alpha honors at the University of Pennsylvania School of Medicine and his A.B. with Phi Beta Kappa honors at . Dr. Ju is a co-founder of Zoomi, Inc., currently serves as a member of the board of directors for Zoomi and for Brickell Biotech, Inc., and is a trustee of the Morristown Medical Center Foundation.

12:35 pm Q & A 28 Open to all meeting attendees CME Credit: 0 NOTES American DermatoEpidemiology ______Network (ADEN) SYMPOSIUM ______Thursday, May 7, 2015 12:00 pm - 1:45 pm Salon C, Hilton Atlanta

______

______246 Quality of life is equivalent between atopic dermatitis patients managed through a direct-access online model compared to in-office care:A ______randomized controlled trial. April W. Armstrong, Mary Ann Johnson, ______Steven Lin, Caitlin Clark, Aleksandra G. Florek and Fu-Tong Liu. Aurora, CO ______and Sacramento, CA.

______267 the impact of chocolate consumption on acne vulgaris. Jenifer Rae ______Lloyd, Gregory Raymond Delost, Jacqueline Selph, Maria Ermenia Delost and Rachael J Pohle-Krauza. Cleveland, OH; Erie, PA and Youngstown, OH. ______307 sustained reduction in skin biopsies after 5-FU treatment. Joanna L Walker, Moniyka Sachar, Hyemin Pomerantz, Suephy C. Chen, Susan Swetter, Robert Dellavalle, George ______Stricklin and Martin A Weinstock. Providence, RI; Atlanta, GA; Palo Alto, CA; Denver, CO ______and Nashville, TN. ______311 pigmentary traits and indoor tanning bed use among women in the United States. ______Wen-Qing Li, Eunyoung Cho, Shaowei Wu and Abrar A. Qureshi. Providence, RI. ______320 Childhood eczema is associated with anemia in 18 US population-based studies. ______Jonathan Silverberg, Kerry E Drury. Chicago, IL. ______

______NOTES ______

29 FREE ADMISSION FOR ALL SID ATTENDEES CME Credit: 0 ASSOCIATE MEETINGS American Acne and Rosacea Society (AARS) 4th Annual Thursday, May 7, 2015 Scientific Symposium Pediatric Dermatology Research Alliance/ Society for Pediatric Dermatology Session 7:00 am – 8:00 am Thursday, May 7, 2015 12:00 pm – 1:45 pm Grand Ballroom, Hilton Atlanta Room 204-207, Hilton Atlanta

American Dermato-Epidemiology Network 12:00 pm welcome and Red Hot 2015 Updates from AARS Symposium (ADEN) Diane Thiboutot, AARS Past-President, Penn State University, Hershey, PA, USA 12:00 pm – 1:45 pm Salon C, Hilton Atlanta

12:10 pm Acne Vaccines Targeting Secretory CAMP Factor of Propionibacterium Acnes American Acne and Rosacea Society (AARS) Chun-Ming Eric Huang, Division of Dermatology, University of California, San Diego, Scientific 4th Annual Scientific Symposium San Diego, CA, USA; Mentor: Richard Gallo 12:00 pm – 1:45 pm Grand Ballroom, Hilton Atlanta

12:25 pm improving Pediatric Acne Management: A Prospective Multicenter Study of Academic/Industry Session Case-Based Guideline Education Panel Discussion Lawrence Eichenfield, Dermatology, University of California, San Diego, San Diego, CA; 12:00 pm – 12:45 pm Pediatric Dermatology, Rady Children’s Hospital, San Diego, CA, USA Individual Meetings (set up in advance by the SID) – Room 203, Hilton Atlanta 12:40 pm A Meta-Analysis of Laboratory Monitoring During Treatment with Isotretinoin 12:00 pm - 1:45 pm Joslyn Kirby, College of Medicine, Penn State Hershey Medical Center, Hershey, PA, USA; Mentor: Diane Thiboutot International Society for Cutaneous Lymphomas/Cutaneous T-Cell Lymphoma Symposium (ISCL/CTCL) 12:55 pm pentobra: A Novel Antimicrobial Compound with Lytic Activity Against 12:00 pm – 2:00 pm Propionibacterium Acnes Room 204-207 – Hilton Atlanta Stephanie Kao, Department of Medicine, Division of Dermatology, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA; National Rosacea Society Research Mentor: Jenny Kim Workshop 12:00 pm – 1:45 pm 1:10 pm Nitric Oxide Releasing Nanoparticles Effectively Prevent P. Acnes-Induced Inflammation Salon D, Hilton Atlanta by Both Clearing the Organism and Inhibiting Microbial Stimulation of the Innate Immune Response The National Eczema Association Gabrielle Wei, Department of Medicine, Division of Dermatology, David Geffen School Reception– The Decade of Eczema! of Medicine, UCLA, Los Angeles, CA, USA; 5:00 pm – 6:30 pm Mentor: Jenny Kim Crystal Ballroom, Hilton Atlanta

1:25 pm Skin Microbiome Characterizations are Biased by Sequencing Approach Jacquelyn Meisel, Department of Dermatology, University of Pennsylvania, Philadelphia, PA, USA; Mentor: Elizabeth Grice NOTES

1:40 pm closing Comments ______Diane Thiboutot, AARS Past-President, Penn State University, Hershey, PA, USA ______Visit www.acneandrosacea.org for more information ______about the AARS and its membership! ______

30 Open to all meeting attendees CME Credit: 0 NOTES International Society for ______Cutaneous Lymphomas / ______Cutaneous T-Cell Lymphoma ______Symposium (ISCL/CTCL) ______

______Thursday, May 7, 2015 12:00 pm – 2:00 pm room 204-207, Hilton Atlanta ______

______12:00 pm iscl Announcements with deli lunch ______8 minutes for presentation + 2 minutes for Q&A and change of speaker

______1. 12:15 pm cutaneous Lymphoma Foundation’s Young Investigator’s Award ______2. 12:25 pm targeting tumor-associated macrophages with anti-CSF-1R antibodies as a ______strategy for inhibiting T cell lymphoma tumorigenesis. Sam Hwang, Xuesong Wu, Yasutomo Imai. Poster #534 ______3. 12:35 pm epigenetic changes in the GPi-linked biosynthetic pathway underlie down ______regulation of CD52 and resistance of CTCL patients to alemtuzumab. ______Jessica E. Teague, Ga-Young Lee, Ahmed Gehad, Elizabeth Lowry, David C. Fisher, Thomas S. Kupper, Rachael Clark. Poster #421 ______4. 12:45 pm slow-cycling cells in cutaneous T-cell lymphoma: A dynamic subpopulation with ______reduced chemosensitivity and increased tumorigenic potential. Wasakorn T. ______Kittipongdaja, Xuesong Wu, Stefan M. Schieke. Poster #117

______5. 12:55 pm VEGF-A and PlGF are involved in progression of cutaneous T-cell lymphoma. Tomomitsu Miyagaki, Makoto Sugaya, Tomonori Oka, Naomi Takahashi, Makiko ______Kawaguchi, Hiraku Suga, HIdeki Fujita, Shinichi Sato. Poster #188 ______6. 1:05 pm rapamycin alters the metabolic phenotype in human cutaneous T-cell lymphoma. ______Wasakorn T. Kittipongdaja, Xuesong Wu, Sam Hwang, Stefan M. Schieke. Poster #126

______7. 1:15 pm Circulating cell-free DNA is increased in sera of Sézary syndrome patients. ______Zuolin Ying, Timothy Langridge, Madeleine Duvic, Xiao Ni. Poster #101 ______8. 1:25 pm Adolescent and young adult cutaneous lymphomas: Clinical spectrum and autoimmunity. Gregory R. Delost, Jacqueline Selph, Ritva Vyas, Kord Honda, ______Kevin D. Cooper. Poster #332 ______9. 1:35 pm low dose irradiation kills malignant T cells, spares benign T cells and is a potentially ______curative therapy for mycosis fungoides. Elizabeth Lowry, Tiago R. Matos, Victor Huang, Rei Watanabe, Ahmed Gehad, Jessica E. Teague, Phillip Devlin, ______thomas S. Kupper, Rachael Clark. Poster #415 ______10. 1:45 pm whole genome sequencing reveals oncogenic mutations in mycosis fungoides. ______Laura Y. McGirt, Peilin Jia, Devin Baerenwald, Robert J. Duszynski, John A. Zic, Jeffrey Zwerner, Zhongming Zhao, Christine M. Eischen. Poster #138 ______

31 Open to all meeting attendees CME Credit: 3 ASSOCIATE MEETINGS CONCURRENT MINI-SYMPOSIUM 1 AUTO-IMMUNITY Thursday, May 7, 2015 Pediatric Dermatology Research Alliance/ Thursday, May 7, 2015 2:00 pm – 5:00 pm Salon E, Hilton Atlanta Society for Pediatric Dermatology Session 7:00 am – 8:00 am Room 204-207, Hilton Atlanta

Presiders: Kiyoshi Ariizumi, PhD and Jan Dutz, MD American Dermato-Epidemiology Network 1. Delineation of ST18 role in the pathogenesis of pemphigus vulgaris. D. Vodo, S Geller, E. Symposium (ADEN) Ben-Asher, T. Olender, I. Goldberg, J. Nosgorodsky, A. Alkelai, P. Tatarsky, T. Zeeli, S. Baum, A. 12:00 pm – 1:45 pm Barzilai, I. Saleh, D. Zillikens, D. Lancet and O. Sarig, E. Sprecher. Tel Aviv, Israel; Rehovot, Israel Salon C, Hilton Atlanta and Luebeck, Germany. 2:00 pm, Poster #066 American Acne and Rosacea Society (AARS) 2. IL-13 receptor alpha 1 downregulation as a protective mechanism and therapeutic target in Scientific 4th Annual Scientific Symposium pemphigus. Kristina Seiffert-Sinha, Elizabeth Z. Welch, Rama Dey-Rao and Animesh A. Sinha. 12:00 pm – 1:45 pm Buffalo, NY. 2:12 pm, Poster #069 Grand Ballroom, Hilton Atlanta

3. Pemphigus foliaceus patients have IgG4 antibodies that recognize Amb a 1, a component from Academic/Industry Session short ragweed pollen allergen. Ye Qian, Joseph S. Jeong and Luis A. Diaz. Chapel Hill, NC. Panel Discussion 2:24 pm, Poster # 092 12:00 pm – 12:45 pm

4. Anti-BP180 IgG4 autoantibodies are inhibitory in BP in BP180 humanized mouse model. Individual Meetings (set up in advance Yagang Zuo, Flor Evangelista, Antonio Guilabert, Ning Li, Luis A. Diaz and Zhi Liu. Chapel Hill, by the SID) – Room 203, Hilton Atlanta NC. 2:36 pm, Poster #091 12:00 pm - 1:45 pm 5. Collagen XVII autoantibodies are present in Parkinson’s Disease patients and co-localize with International Society for Cutaneous tyrosine hydroxylase in the substantia nigra. Kelly Messingham, Nandakumar Narayanan, Sa- mantha Aust, Joseph Helfenberger, Martin Cassell, Stephanie Alberico and Janet A. Fairley. Iowa Lymphomas/Cutaneous T-Cell City, IA. 2:48 pm, Poster #084 Lymphoma Symposium (ISCL/CTCL) 12:00 pm – 2:00 pm 6. IL-7 blockade prevents the onset of alopecia areata. Zhenpeng Dai, Luzhou Xing, Ali Jabbari, Room 204-207 – Hilton Atlanta Raphael Clynes and Angela Christiano. New York, NY. 3:00 pm, Poster #089 National Rosacea Society Research 7. Alopecia areata skin transcriptome correlates with disease severity and response to treatment. Workshop Ali Jabbari, Jane E. Cerise, Julian Mackay-Wiggan, Madeleine Duvic, Maria Hordinsky, Vera H. 12:00 pm – 1:45 pm Price, David Norris, Raphael Clynes and Angela Christiano. New York, NY; Houston, TX; Min- Salon D, Hilton Atlanta neapolis, MN; San Francisco, CA and Denver, CO. 3:12 pm, Poster #079 The National Eczema Association 8. essential requirement for IRF7 in the production of autoantibodies in murine lupus. Fumi Reception– The Decade of Eczema! Miyagawa and Hideo Asada. Kashihara, Japan. 3:24 pm, Poster #054 5:00 pm – 6:30 pm 9. Expanded ß T cell clones are present in the healed lesions of psoriasis and likely represent the Crystal Ballroom, Hilton Atlanta autoreactive T cells of origin. Tiago R. Matos, John T. O’Malley, Ahmed Gehad, Jessica E. Teague, Elizabeth Lowry, Harlan Robins, Thomas S. Kupper, James Krueger and Rachael Clark. Boston, MA; Seattle, WA and New York, NY. 3:36 pm, Poster #082 10. T-bet-deficient mice are protected from imiquimod-induced psoriasis-like dermatitis due to the NOTES protective IL-4 producing NKT cells. Dinghong Wu, Ling Han, Jingwen Deng, Li Zhou, Chuan- jian Lu and Qing-Sheng Mi. Guangzhou, China and Detroit, MI. 3:48 pm, Poster #093 ______11. A pathogenic role for IL-9 in psoriasis: IL-9 producing T cells are frequent in human psoriasis and IL-9 enhances dermatitis in two IL-17 dependent mouse models of psoriasiform dermatitis. ______Ahmed Gehad, Christoph Schlapbach, Tiago R. Matos, Jessica E. Teague, Victor Huang, Elizabeth ______Lowry, Thomas S. Kupper and Rachael Clark. Boston, MA and Bern, Switzerland. 4:00 pm, Poster #072 ______

12. Skin-homing and systemic T-cell subsets show higher activation in atopic dermatitis versus ______psoriasis. Tali Czarnowicki, Juana Gonzalez, Avner Shemer, Mayte Suarez-Farinas, James Krueger ______and Emma Guttman-Yassky. New York, NY and Tel Aviv, Israel. 4:12 pm, Poster #055

32 Open to all meeting attendees CME Credit: 3 NOTES CONCURRENT MINI-SYMPOSIUM 2 ______CARCINOGENESIS & CANCER GENETICS ______Thursday, May 7, 2015 2:00 pm – 5:00 pm Grand Ballroom, Hilton Atlanta ______Presiders: Kenneth Tsai, MD/PhD and Xiao-Jing Wang, MD/PhD

______1. Lack of resistant SMO mutations and decreased mutational load of Gorlin-associated basal cell cancers explain marked response to smoothened inhibitors. Kavita Sarin, Melika Rezaee, ______Prajakta Jaju, Anne Lynn S. Chang, Anthony Oro, Ervin Epstein and Jean Tang. Stanford, CA and ______Oakland, CA. 2:00 pm, Poster #135

______2. Smoothened (SMO) resistance is driven by PI3K–Akt signaling in a subset of murine ASZ001 BCC cells displaying tumor-initiating cell (TIC)-like characteristics. Guang C. Jin, Yucui Zhu, ______Arianna Kim and David R. Bickers. New York, NY. 2:12 pm, Poster #115 ______3. Epidermal differentiation protects against Hedgehog pathway-driven tumorigenesis. KL Harms, ______M. Grachtchouk, A. Ermilov, K. Pais, A. Photenhauer, D. Wilbert, D. Metzger, P. Chambon and AA Dlugosz. Ann Arbor, MI and Illkirch, France. 2:24 pm, Poster #155 ______4. Tumor-intrinsic PD-1 signaling promotes Merkel cell carcinoma growth. Sonja Kleffel, Christian Posch, Stephen Fucaloro, Margot C. Joubert, Manisha Thakuria, Thomas S. Kupper and Tobias ______Schatton. Boston, MA. 2:36 pm, Poster #123

______5. Upregulation of pro-oncogenic Fbxw7 substrates in Merkel cell carcinoma. Monique E. ______Verhaegen, Doris Mangelberger, Ehab Nazzal, Kristin Rybski, Jack Weick, Tracy Vozheiko, Dawn Wilbert and Andrzej Dlugosz. Ann Arbor, MI. 2:48 pm, Poster #124 ______6. Identification of a pre-programmed metastasis-associated homozygous deletion in Chr2q37.3 ______in human melanoma. Kasey L. Couts, Ichiro Nakachi, Yuchun Luo, Hieu Van, Akihiro Fujisawa, ______Steven Robinson, William Robinson, Mark Geraci and Mayumi Fujita. Aurora, CO and Denver, CO. 3:00 pm, Poster #106 ______7. Mutation burden is associated with gender and survival in metastatic melanoma. Sameer ______Gupta, Mykyta Artomov, William Goggins, Mark Daly and Hensin Tsao. Boston, MA and Shatin, ______Hong Kong. 3:12 pm, Poster #134 ______8. Periostin is a key niche component for melanoma wound metastasis. Keitaro Fukuda, Eiji Sugihara, Shoichiro Ohta, Kenji Izuhara, Takeru Funakoshi, Masayuki Amagai and Hideyuki Saya. ______Tokyo, Japan and Saga, Japan. 3:24 pm, Poster #098 ______9. Neurofibroma development is dependent on the presence of peripheral neurons in the tumor ______microenvironment. Chung-Ping Liao, Sanjay Pradhan, Zhiguo Chen, Amish J. Patel, Chiachi Liu, Reid C. Booker and Lu Q. Le. Dallas, TX. 3:36 pm, Poster #108 ______10. A counter-intuitive role for caspase 3 in promoting genetic instability and skin carcinogenesis. Xinjian Liu. Durham, NC. 3:48 pm, Poster #128 ______11. Identification of the KNSTRN proteome by APEX2 targeting. Carolyn Lee, Angela Mah, Christie ______Nguyen and Paul Khavari. Stanford, CA and Palo Alto, CA. 4:00 pm, Poster #145 ______12. Evidence for reciprocal interaction between bone marrow and cutaneous epithelial cells. ______Rebecca J. Morris, Kelly Johnson, Kelsey Boland, Nyssa Readio, Heuijoon Park, Derek Gordon and Douglas Londono. Austin, MN and Piscataway, NJ. 4:12 pm, Poster #118 ______

33 Open to all meeting attendees CME Credit: 3 ASSOCIATE MEETINGS CONCURRENT MINI-SYMPOSIUM 3 EPIDEMIOLOGY Thursday, May 7, 2015

Pediatric Dermatology Research Alliance/ Thursday, May 7, 2015 2:00 pm – 5:00 pm Salon C, Hilton Atlanta Society for Pediatric Dermatology Session 7:00 am – 8:00 am Room 204-207, Hilton Atlanta Presiders: Joel Gelfand, MD and Robert Kirsner, MD/PhD American Dermato-Epidemiology Network 1. Melanoma screening consequences. Martin A. Weinstock, Laura Ferris, Melissa Saul, Alan Symposium (ADEN) Geller, Patricia Risica, Francis Solano, John Lagnese and John Kirkwood. Providence, RI; Pitts- 12:00 pm – 1:45 pm burgh, PA and Boston, MA. 2:00 pm, Poster #322 Salon C, Hilton Atlanta

2. Duration of oral antibiotic therapy for the treatment of adult acne: A retrospective analysis American Acne and Rosacea Society (AARS) investigating adherence to guideline recommendations and opportunities for cost-savings. Scientific 4th Annual Scientific Symposium Chelsey S. Straight, Young S. Lee, Guodong S. Liu and Joslyn Kirby. Hershey, PA. 2:12 pm, 12:00 pm – 1:45 pm Poster #296 Grand Ballroom, Hilton Atlanta

3. Air pollution is associated with increased eczema prevalence and severity. Parul Kathuria and Academic/Industry Session Jonathan Silverberg. Chicago, IL. 2:24 pm, Poster #327 Panel Discussion 12:00 pm – 12:45 pm 4. Ozone exposure and extrinsic skin aging: Results from the SALIA cohort. Anke Hüls, Tamara Schikowski, Ursula Krämer, Dorothee Sugiri, Sabine Stolz, Andrea Vierkoetter and Jean Individual Meetings (set up in advance Krutmann. Düsseldorf, Germany and Basel, Switzerland. 2:36 pm, Poster #286 by the SID) – Room 203, Hilton Atlanta 12:00 pm - 1:45 pm 5. Incidence of skin cancer in a cohort of 1278 patients with vitiligo, 2001-2013. Liza Gill, Gor- don Jacobsen, Richard Krajenta, Henry W. Lim, Iltefat H. Hamzavi and Melody J. Eide. Detroit, MI and East Lansing, MI. 2:48 pm, Poster #287 International Society for Cutaneous Lymphomas/Cutaneous T-Cell 6. Increased risk of pneumonia among patients with psoriasis: A population-based cohort study in Lymphoma Symposium (ISCL/CTCL) the United Kingdom. Junko Takeshita, Daniel B. Shin, Alexis Ogdie and Joel Gelfand. Philadel- 12:00 pm – 2:00 pm phia, PA. 3:00 pm, Poster #289 Room 204-207 – Hilton Atlanta

7. Long-term efficacy of topical 5-fluorouracil 5% cream in treating actinic keratosis. Hyemin National Rosacea Society Research Pomerantz, Daniel Hogan, David Eilers, Susan Swetter, Suephy C. Chen, Sharon Jacob, Erin M. Workshop Warshaw, George Stricklin, Robert Dellavalle, Navjeet Sidhu-Malik, Nellie Konnikov, Victoria 12:00 pm – 1:45 pm Werth, Jonette Keri, Robert Lew and Martin Weinstock. Providence, RI; Bay Pines, FL; Hines, Salon D, Hilton Atlanta IL; Palo Alto, CA; Atlanta, GA; San Diego, CA; Minneapolis, MN; Nashville, TN; Denver, CO; Durham, NC; Boston, MA; Philadelphia, PA and Miami, FL. 3:12 pm, Poster #291 The National Eczema Association Reception– The Decade of Eczema! 8. A large cohort study of lithium use and melanoma incidence and progression. Maryam M. Asgari, Zheng Zhu, E. Margaret Warton, Charles Quesenberry, Bruce Fireman and Andy Chien. 5:00 pm – 6:30 pm Oakland, CA and Seattle, WA. 3:24 pm, Poster #305 Crystal Ballroom, Hilton Atlanta

9. Childhood versus adulthood sun exposure and skin cancer risk in Caucasian post-menopausal women in the Women’s Health Initiative. Katherine J. Ransohoff, Mina S. Ally, Marcia Stefanick, Elizabeth Keiser, Katrina Spaunhurst, Kristopher Kapphahn, Sherry Pagoto, Catherine Messina, Haley Hedlin, JoAnn E. Manson and Jean Y. Tang. Redwood City, CA; Stanford, CA; San Diego, NOTES CA; Cleveland, OH; Boston, MA and Stony Brook, NY. 3:36 pm, Poster #315

10. Incidence and survival of sebaceous carcinoma in the United States. Raghav Tripathi, Zhengyi ______Chen, Li Li and Jeremy Bordeaux. Cleveland, OH. 3:48 pm, Poster #334 ______11. Disparities in sunburns, photoprotection, indoor tanning, and skin cancer screening among U.S. ______men and women in same- and opposite-sex relationships. Howa Yeung and Suephy C. Chen. Atlanta, GA. 4:00 pm, Poster #284 ______

12. Young adults who frequently indoor tan report decreased sun-protective practices and low rates ______of total body skin examinations. Alexander H. Fischer, Timothy Wang, Sewon Kang and Anna L. ______Chien. Baltimore, MD. 4:12 pm, Poster #314

34 Open to all meeting attendees CME Credit: 3 NOTES CONCURRENT MINI-SYMPOSIUM 4 ______GENE THERAPY & CLINICAL THERAPEUTICS ______Thursday, May 7, 2015 2:00 pm – 5:00 pm Salon A/B, Hilton Atlanta ______Presiders: Mei Chen, PhD and M. Joyce Rico, MD/MBA

______1. Phase I clinical trial for recessive dystrophic epidermolysis bullosa using genetically corrected autologous keratinocytes. Zurab Siprashvili, Ngon T. Nguyen, Emily Gorell, Kylie Loutit, Phuong ______Khuu, Louise K. Furukawa, H P. Lorenz, Thomas H. Leung, Douglas R. Keene, Paul Khavari, ______Alfred Lane, Jean Y. Tang and M. Peter Marinkovich. Stanford, CA; Portland, OR and Palo Alto, CA. 2:00 pm, Poster #418 ______2. Allogeneic mesenchymal stromal cell therapy for children with recessive dystrophic ______epidermolysis bullosa: an open-label, phase 1, single-centre trial. Gabriela Petrof, Su M. Lwin, ______Magdalena Martinez-Quiepo, Alya Abdul-Wahab, Simon Tso, Jemima Mellerio, Ineke Slapen-Cortenbach, Jaap J. Boelens, Jakub Tolar, Paul Veys, Tendai Kadiyirire, Mercy Ofuya, Janet ______L. Peacock, Anna Martinez and John McGrath. London, United Kingdom; Utrecht, Netherlands and Minneapolis, MN. 2:12 pm, Poster #411 ______3. Autologous fibroblasts therapy for recessive dystrophic epidermolysis bullosa. Joanna Jackow, Matthias Titeux, Soeli Charbonnier and Alain Hovnanian. Paris, France. 2:24 pm, Poster #405 ______4. Assessment of amlexanox, an antagonist of nonsense mediated mRNA decay (NMD), for the ______treatment of RDEB. Velina Atanasova, Q. Jiang, J. Uitto and Andrew P. South. Philadelphia, PA. ______2:36 pm, Poster #426

______5. Hematopoietic cell transplantation (HCT) for recessive dystrophic epidermolysis bullosa (RDEB): Reduced intensity conditioning (RIC) has a better outcome than myeloablative ______conditioning (MAC). Jakub Tolar, John McGrath, Mark J. Osborn, Douglas R. Keene, Kristen ______Hook, Maria Hordinsky, David T. Woodley, Mei Chen, Alain Hovnanian, Katsuto Tamai, Bruce Blazar and John Wagner. Minneapolis, MN; London, United Kingdom; Portland, OR; ______Los Angeles, CA; Paris, France; Minneapolis, MN and Osaka, Japan. 2:48 pm, Poster #408

______6. Investigation into the safety and efficacy of human ES/iPS-derived keratinocytes for therapeutic ______reprogramming. Hanson Zhen, Elizaveta Bashkirova, Sandra Melo, Lingjie Li, Jessica Torkelson, Eric Liaw and Anthony Oro. Stanford, CA. 3:00 pm, Poster #428 ______7. Differentiating endothelial cells from human induced pluripotent stem cells. Zongyou Guo, ______Chong Shen, Karl Gledhill, Hasan E. Abaci, Abigail Coffman, Satoru Shinkuma, Claire Higgins, ______Brian Gillette, Samuel K. Sia and Angela Christiano. New York, NY. 3:12 pm, Poster #427 ______8. Regression of cutaneous squamous cell carcinomas induced by topical application of PI3K/ mTOR inhibitors. X Yang, C Marshall, T Dentchev, T Salah, S Shankar, F Stauffer, A Lerchner, F ______Seiler, F Kalthoff and John Seykora. Philadelphia, PA and Basel, Switzerland. 3:24 pm, Poster ______#416

______9. Topically delivered spherical nucleic acid nanoconjugates targeting TNF improve the psoriatic phenotype. Katherine Lewandowski, Weston Daniel, Richard Kang, David Giljohann, Chad ______Mirkin and Amy S. Paller. Chicago, IL; Skokie, IL and Evanston, IL. 3:36 pm, Poster #413 ______10. The effects of bisphosphonates on ectopic soft tissue mineralization caused by mutations in the ______ABCC6 gene: Potential treatment of PXE. Q. Li, John P. Sundberg, Michael A. Levine, Joshua Kingman and J. Uitto. Philadelphia, PA and Bar Harbor, ME. 3:48 pm, Poster # 422 ______11. A novel therapeutic inhibits Rac1 mediated invasion and metastasis in a newly described in vivo ______model of human melanoma. M. C. Winge, Joanna Kovalski, Ngon T. Nguyen, Diane Wu, Ashley ______Zehnder, Paul Khavari and M. Peter Marinkovich. Stanford, CA. 4:00 pm, Poster #412

______12. Novel long-non-coding RNA in melanoma: MIRAT a biomarker of small molecule inhibitor response. Martina Sanlorenzo, Igor Vujic, Christian Posch, Kevin Lai, Kevin Lin, Deborah ______Stephanie Gho, Adrian Moy, Abhinay Gajjala and Susana Ortiz-Urda. San Francisco, CA. ______4:12 pm, Poster #409

35 Open to all meeting attendees CME Credit: 3 ASSOCIATE MEETINGS CONCURRENT MINI-SYMPOSIUM 5 SKIN & HAIR DEVELOPMENTAL BIOLOGY Thursday, May 7, 2015

Pediatric Dermatology Research Alliance/ Thursday, May 7, 2015 2:00 pm – 5:00 pm Salon D, Hilton Atlanta Society for Pediatric Dermatology Session 7:00 am – 8:00 am Room 204-207, Hilton Atlanta

Presiders: Valentina Greco, PhD and Bruce Morgan, PhD American Dermato-Epidemiology Network 1. Polycomb repressive complex maintains epidermal progenitors by repressing key Merkel cell Symposium (ADEN) differentiation genes. Evan Bardot, Carolina Perdigoto and Elena Ezhkova. New York, NY. 12:00 pm – 1:45 pm 2:00 pm, Poster #680 Salon C, Hilton Atlanta

2. Hdac1 and hdac2 are required for maintenance and survival of embryonic and adult epidermal American Acne and Rosacea Society (AARS) stem cells. Matthew LeBoeuf, Fang Liu, Xinyi Zhao, Eric Olson and Sarah Millar. Philadelphia, Scientific 4th Annual Scientific Symposium PA and Dallas, TX. 2:12 pm, Poster #668 12:00 pm – 1:45 pm Grand Ballroom, Hilton Atlanta 3. Wnt signaling controls the reversible differentiation of melanocyte stem cells during their self-renewal. Sun, Hai Hu, Makoto Takeo, Wendy Lee, Mark M. Taketo and Mayumi Ito. Academic/Industry Session New York, NY and Kyoto, Japan. 2:24 pm, Poster #689 Panel Discussion 12:00 pm – 12:45 pm 4. Wnt/ß-catenin signaling marks self-renewing stem cells in multiple epithelial tissues. Mingang Xu, Jeremy Horrell, Heather Gochnauer, Jiawei Cui, Melinda Snitow, Tien Peng, Edward Morrisey Individual Meetings (set up in advance and Sarah Millar. Philadelphia, PA. 2:36 pm, Poster #685 by the SID) – Room 203, Hilton Atlanta 12:00 pm - 1:45 pm 5. Dynamic interactions between nail epithelium and digit bone by Wnt signaling. Makoto Takeo, Christopher S. Hale and Mayumi Ito. New York, NY. 2:48 pm, Poster #664 International Society for Cutaneous 6. Gorab is essential for dermal papilla cells to respond to hedgehog signals during hair follicle Lymphomas/Cutaneous T-Cell formation. Ying Liu, Elizabeth R. Snedecor, Yeun Ja Choi, Ning Yang, Xu Zhang, Yuhuan Xu, Lymphoma Symposium (ISCL/CTCL) Yunlin Han, Evan C. Jones, Kenneth R. Shroyer, Richard A. Clark, Lianfeng Zhang, Chuan Qin 12:00 pm – 2:00 pm and Jiang Chen. Beijing, China and Stony Brook, NY. 3:00 pm, Poster #687 Room 204-207 – Hilton Atlanta

7. Inhibition of JAK-STAT signaling promotes hair growth. Sivan Harel, Claire Higgins, Jane E. National Rosacea Society Research Cerise, James C. Chen, Zhenpeng Dai, Raphael Clynes and Angela Christiano. New York, NY. Workshop 3:12 pm, Poster #682 12:00 pm – 1:45 pm Salon D, Hilton Atlanta 8. Serum response factor (SRF) regulates the development and cyclic regeneration of the hair follicle, and functions in epidermal development in a stage-specific manner. Congxing Lin, The National Eczema Association Aaron Koppel, Alexi Kiss, Liang Ma and Tatiana Efimova. St. Louis, MO. 3:24 pm, Poster #681 Reception– The Decade of Eczema! 9. Rapid hair cycle pattern breakdown during mouse development revealed with the aid of 5:00 pm – 6:30 pm mathematical modeling. Ji Won Oh, Qixuan Wang, Qing Nie and Maksim Plikus. Irvine, CA. Crystal Ballroom, Hilton Atlanta 3:36 pm, Poster #695

10. The LINC complex promotes keratinocyte cell-cell adhesion and hair follicle structure. Rachel Stewart, Amanda Zubek, Kathryn A. Rosowski, Megan King and Valerie Horsley. New Haven, CT. 3:48 pm, Poster #694 NOTES 11. Studying hair cycle clock with the aid of multi-scale diffusion-based mathematical modeling. Ji Won Oh, Qixuan Wang, Qing Nie and Maksim Plikus. Irvine, CA. 4:00 pm, Poster #693 ______

12. Alopecia areata is transferred via activated T-lymphocytes. Eddy H. Wang, Mohsen Khosravi- ______Maharlooei, Reza Jalili, Richard Yu, Aziz Ghahary, Jerry Shapiro and Kevin J. McElwee. ______Vancouver, BC, Canada. 4:12 pm, Poster #673 ______

36 Open to all meeting attendees CME Credit: 0 NOTES MINI-SYMPOSIA MIXERS ______Thursday, May 7, 2015 5:00 pm – 6:00 pm Individual Concurrent Meeting Rooms, Hilton Atlanta ______

______Immediately following the afternoon Concurrent Minisymposia Sessions, a 45-minute mixer will be held. ______Presenters, moderators and attendees will be able to interact as they enjoy light refreshments and snacks These mixers are designed to encourage informal discussion, mingling and networking among SID ______meeting attendees. ______NOTES ______

37 PRE-REGISTRATION REQUIRED CME Credit: 0 ASSOCIATE MEETINGS Social Event Thursday, May 7, 2015

Pediatric Dermatology Research Alliance/ Thursday, May 7, 2015 6:30 pm – 10:30 pm Georgia Aquarium Society for Pediatric Dermatology Session 7:00 am – 8:00 am Room 204-207, Hilton Atlanta

American Dermato-Epidemiology Network Join us on Thursday, May 7, 2015 from 6:30 p.m. – 10:30 p.m. for the annual SID Social Event, this year Symposium (ADEN) at the Georgia Aquarium. Featuring more animals than any other aquarium in more than ten million gallons of water and through a path of more than 60 exhibits, the Georgia Aquarium entertains, 12:00 pm – 1:45 pm engages and educates. It is a leading facility for aquatic animal conservation and research and is the Salon C, Hilton Atlanta only integration of an aquarium and a veterinarian teaching hospital. Come see for yourself! American Acne and Rosacea Society (AARS) The SID is pleased to announce that the Social Event will take place throughout the entire venue. Scientific 4th Annual Scientific Symposium 12:00 pm – 1:45 pm TICKETED EVENT: PRE-REGISTRATION REQUIRED Grand Ballroom, Hilton Atlanta

Buses depart from the Hilton Atlanta beginning at 6:00 pm. Buses will begin shuttling guests back to the Academic/Industry Session hotel beginning at 8:30 pm. Panel Discussion 12:00 pm – 12:45 pm

Individual Meetings (set up in advance by the SID) – Room 203, Hilton Atlanta 12:00 pm - 1:45 pm

International Society for Cutaneous Lymphomas/Cutaneous T-Cell Lymphoma Symposium (ISCL/CTCL) 12:00 pm – 2:00 pm Room 204-207 – Hilton Atlanta

National Rosacea Society Research Workshop 12:00 pm – 1:45 pm Salon D, Hilton Atlanta

The National Eczema Association Reception– The Decade of Eczema! 5:00 pm – 6:30 pm Crystal Ballroom, Hilton Atlanta

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39 Friday Sessions

PAGE TITLE

38-39 Meeting-at-a-Glance

40 Pediatric Dermatology Research Alliance/Society for Pediatric Dermatology Session

41 Business Meeting for Members

42 Plenary Session II

43 Stephen Rothman Memorial Award

44 Herman Beerman Lecture

45 State-of-the-Art Plenary Lecture 3

46 State-of-the-Art Plenary Lecture 4

47 National Institute Of and Infectious Diseases (Niaid) Symposium Friday, May 8 48 Research in Cutaneous Surgery (RCS) Symposium

Women’s Dermatologic Society Luncheon

49 Concurrent Mini-Symposium 6: Clinical Research (Observations, Pathophysiology & Outcomes)

50 Concurrent Mini-Symposium 7: Epidermal Function & Barrier Function

51 Concurrent Mini-Symposium 8: Genetic Disease & Gene Regulation

52 Concurrent Mini-Symposium 9: Innate Immunity, Inflammation & Microbiology

53 Concurrent Mini-Symposium 10: Pigmentation & Melanoma

54 Concurrent Mini-Symposium 11: Interdisciplinary Spotlight: Skin Cancer

55 Mini-Symposia Mixers

56-57 North American Hair Research Society (NAHRS) Scientific Session and Annual Business Meeting

National Psoriasis Foundation (NPF) Scientific Advisory Board Meeting

National Alopecia Areata Foundation (NAAF) Reception

58 Trainee Dinner

ASSOCIATE Meeting-At-A-Glance MEETINGS

Friday, May 8, 2015 Friday, May 8, 2015 ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Pediatric Dermatology Research Alliance/ 7:00 am – 8:00 am Pediatric Dermatology Research Alliance/ Society for Pediatric Dermatology Session Society for Pediatric Dermatology Session Room 204-207, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– 7:00 am – 8:00 am Registration 7:30 am – 4:00 pm Room 204-207, Hilton Atlanta Convention Registration Area, First Floor, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– NIAID Symposium Business Meeting for Members 7:45 am – 8:30 am 12:00 pm – 1:45 pm Grand Ballroom, Hilton Atlanta Grand Ballroom, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Plenary Session II 8:30 am – 9:30 am Grand Ballroom, Hilton Atlanta Research in Cutaneous Surgery (RCS) ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Symposium Stephen Rothman Memorial Award 9:30 am – 9:45 am 12:00 pm – 1:45 pm Presented to Ervin H. Epstein, Jr., MD Salon A/B, Hilton Atlanta Grand Ballroom, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Women’s Dermatologic Society (WDS) Herman Beerman Lecture 9:45 am – 10:15 am Luncheon Cancer immunotherapy via blockade of the PD 1 pathway 12:00 pm – 1:45 pm Drew M. Pardoll, MD/PhD Crystal Ballroom, Hilton Atlanta Grand Ballroom, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– State-of-the-Art Plenary Lecture 3 10:15 am – 10:45 am North American Hair Research Translational Research in Vitiligo: Launching a New Era of Targeted Treatment Society (NAHRS)-Scientific Session and John E. Harris, MD/PhD Annual Business Meeting Grand Ballroom, Hilton Atlanta 6:00 pm – 9:30 pm ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Grand Ballroom, Hilton Atlanta State-of-the-Art Plenary Lecture 4 10:45 am – 11:15 am Mitochondria as Signaling Organelles National Psoriasis Foundation (NPF) Navdeep S. Chandel, PhD Scientific Advisory Board Meeting Grand Ballroom, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– 6:00 pm – 9:30 pm Poster Session II 11:15 am – 1:15 pm Room 203, Hilton Atlanta Poster #’s 002 - 244 Even & #’s 491 – 735 Odd Galleria Exhibit Hall, Hilton Atlanta National Alopecia Areata ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Foundation (NAAF) Reception Research in Cutaneous Surgery (RCS) 12:00 pm – 1:45 pm 6:00 pm – 9:30 pm Symposium Room 206-207, Hilton Atlanta Salon A/B, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Women’s Dermatologic Society Luncheon 12:00 pm – 1:45 pm Crystal Ballroom, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– NIAID Symposium 12:00 pm – 1:45 pm NOTES Understanding Host Defense In Atopic Dermatitis Grand Ballroom, Hilton Atlanta ______––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Concurrent Mini-Symposia 2:00 pm – 5:00 pm ______Clinical Research (Observations, Pathophysiology & Outcomes) ______Salon D, Hilton Atlanta Epidermal Structure & Barrier Function ______Salon C, Hilton Atlanta ______Genetic Diseases & Gene Regulation ______Rooms 204-207, Hilton Atlanta Innate Immunity, Inflammation & Microbiology ______Salon E, Hilton Atlanta ______Pigmentation & Melanoma ______Salon A/B, Hilton Atlanta interdisciplinary Spotlight: Skin Cancer Grand Ballroom, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Mini-Symposia Mixers 5:00 pm – 6:00 pm Individual Concurrent Meeting Rooms –––––––––––––––––––––––––––––––––––––––––––––––––––––––––––

40 NOTES Meeting-At-A-Glance ______Friday, May 8, 2015 ______––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– ______North American Hair Research Society- 6:00 pm – 9:30 pm Scientific Session and Annual Business Meeting ______Grand Ballroom, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– ______National Psoriasis Foundation Scientific 6:00 pm – 9:30 pm ______Advisory Board Meeting Room 203, Hilton Atlanta ______––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– National Alopecia Areata Foundation 6:00 pm – 9:30 pm ______(NAAF) Reception Room 206 & 207, Hilton Atlanta ______––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Trainee Dinner 7:00 pm - 9:00 pm ______Crystal Ballroom, Hilton Atlanta ______Ticketed event: pre-registration required ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– ______NOTES ______

41 Open to all meeting attendees CME Credit: 0 ASSOCIATE MEETINGS Meeting-At-A-Glance PEDIATRIC DERMATOLOGY AT THE SOCIETY FOR INVESTIGATIVE DERMATOLOGY Friday, May 8, 2015

Pediatric Dermatology Research Alliance/ Friday, May 8, 2015 7:00 am - 8:00 am Rooms 204-207, Hilton Atlanta Society for Pediatric Dermatology Session (COFFEE WILL BE SERVED) 7:00 am – 8:00 am Room 204-207, Hilton Atlanta 7:00 am introduction and Welcome NIAID Symposium Amy Paller, MD/MS, Northwestern University 12:00 pm – 1:45 pm Grand Ballroom, Hilton Atlanta

Research in Cutaneous Surgery (RCS) 7:05 am Abstracts #90, 272, and 459: IFN-γ pathway blockade and use of Symposium oral ruxolitinib to induce hair regrowth in alopecia areata, Angela 12:00 pm – 1:45 pm Christiano et al, Columbia University, New York Salon A/B, Hilton Atlanta

Women’s Dermatologic Society (WDS) 7:15 am special Presentation: Luncheon 12:00 pm – 1:45 pm Ectodermal dysplasias: new approaches to disease Crystal Ballroom, Hilton Atlanta modeling and treatment design Maranke Koster PhD, University of Colorado North American Hair Research Society (NAHRS)-Scientific Session and Annual Business Meeting 7:40 am Abstract #255 6:00 pm – 9:30 pm Epicutaneous sensitization to peanuts and other food allergens by patch testing Grand Ballroom, Hilton Atlanta promotes Th2 polarization with increased IL-33. Benjamin Ungar et al., Rockefeller University, New York National Psoriasis Foundation (NPF) Scientific Advisory Board Meeting 6:00 pm – 9:30 pm 7:50 am Discussion and Concluding Remarks Room 203, Hilton Atlanta

National Alopecia Areata Foundation (NAAF) Reception Special thanks to the Pediatric Dermatology Research Alliance and the Society 6:00 pm – 9:30 pm for Pediatric Dermatology for supporting these sessions. Room 206-207, Hilton Atlanta

NOTES ______NOTES

______

42 Open to all meeting attendees CME Credit: 0 NOTES BUSINESS MEETING FOR MEMBERS ______Friday, May 8, 2015 7:45 am - 8:30 am Grand Ballroom, Hilton Atlanta ______

______Honorary Membership is one of the highest honors the Society for Investigative Dermatology (SID) bestows. Each of the following SID Members has made sustained and important contributions to the re- ______search base in cutaneous biology and has contributed to the organizational success of the SID. Each has ______also excelled in their role as a mentor to numerous individuals over the course of their academic career. ______Congratulations to Richard A. Clark, Shinji Shimada, and Stuart H. Yuspa on their appointment to SID ______Honorary Membership! ______Richard A. Clark, MD ______SUNY Stony Brook ______Stony Brook, New York ______Dr. Clark has demonstrated outstanding service to the Society as a former SID ______President and Board Member, along with service on multiple Standing and ad hoc Committees. He has made major scientific contributions to the understanding of ______connective tissue biomechanics and wound healing and regenerative medicine as ______well as animal models to advance these areas of investigation. ______Shinji Shimada, MD/PhD ______University of Yamanashi ______Yamanashi, Japan

______Dr. Shimada has made significant contributions to fostering global research col- ______laborations in Dermatology. He was the Secretary-Treasurer and President of the Japanese Society for Investigative Dermatology (JSID), and lead organizer of the ______2008 International Investigative Dermatology (IID) meeting in Kyoto. His leader- ______ship helped set the stage for the development of what is now the International Societies for Investigative Dermatology (ISID). Dr. Shimada has made major scientific contributions to the understanding of cutane- ______ous immune systems clarifying the role of innate and acquired immunity against melanoma and viral ______infections in the skin. ______

______Stuart H. Yuspa, MD ______National Cancer Institute, NIH Bethesda, Maryland ______Dr. Yuspa has been an SID Member for three decades. During this time and throughout his career at the National Cancer Institute, he has mentored countless ______numbers of young investigators, many of whom are now in leadership positions ______worldwide. He has made major scientific contributions to current understanding of the mechanisms of the pre-metastatic stages of cancer pathogenesis. By employing skin carcinogenesis as ______a model, Dr. Yuspa’s work has delineated the signaling pathways associated with oncogenic RAS-induced ______benign squamous neoplasia and the multistep progression to squamous cell carcinoma. ______

43 Open to all meeting attendees CME Credit: 1 ASSOCIATE MEETINGS PLENARY SESSION II Presiders: Anthony Gaspari, MD and My Mahoney, PhD Friday, May 8, 2015

Pediatric Dermatology Research Alliance/ Friday, May 8, 2015 8:30 am - 9:30 am Grand Ballroom, Hilton Atlanta Society for Pediatric Dermatology Session 7:00 am – 8:00 am Room 204-207, Hilton Atlanta

1. NuMA/microtubule interactions are critical for asymmetric cell divisions and epidermal NIAID Symposium morphogenesis. Lindsey Seldin and Terry Lechler. Durham, NC. 8:30 am, Poster #371 12:00 pm – 1:45 pm Grand Ballroom, Hilton Atlanta 2. Inducing hair follicle neogenesis with 3 protein factors. Sabrina Mai-Yi Fan, Chien-Mei Yen, Szu-Hua Pan, Yu-Ju Chen and Sung-Jan Lin. Taipei, Taiwan. 8:42 am, Poster #671 Research in Cutaneous Surgery (RCS) Symposium 3. Silymarin mediated DNA repair is a mechanism for suppression of UVB induced Treg cells and 12:00 pm – 1:45 pm prevention of photocarcinogenesis. Hui Li, Donggou He, Tripti Singh, Ram Prasad, Santosh K. Salon A/B, Hilton Atlanta Katiyar and Hui Xu. Birmingham, AL. 8:54 am, Poster #591 Women’s Dermatologic Society (WDS) Luncheon 4. Nesprin-2 declines during skin aging and its loss negatively impacts fibroblast and keratinocyte 12:00 pm – 1:45 pm behavior in vitro. Robert Maidhof, Ying Chen, Uma Santhanam and John Lyga. Suffern, NY. Crystal Ballroom, Hilton Atlanta 9:06 am, Poster #697 North American Hair Research 5. Site-specific genome editing using CRISPR/Cas9 and TALENs for correction of iPS cells derived Society (NAHRS)-Scientific Session and from dominant dystrophic epidermolysis bullosa. Satoru Shinkuma, Zongyou Guo and Angela Annual Business Meeting Christiano. New York, NY. 9:18 am, Poster #419 6:00 pm – 9:30 pm Grand Ballroom, Hilton Atlanta

National Psoriasis Foundation (NPF) Scientific Advisory Board Meeting 6:00 pm – 9:30 pm Room 203, Hilton Atlanta NOTES ______National Alopecia Areata Foundation (NAAF) Reception ______6:00 pm – 9:30 pm ______Room 206-207, Hilton Atlanta ______NOTES ______

44 Open to all meeting attendees CME Credit: 0 NOTES Stephen Rothman ______Memorial Award ______Friday, May 8, 2015 9:30 am - 9:45 am Grand Ballroom, Hilton Atlanta ______Introduction by: S. Wright Caughman, MD ______Ervin H. Epstein, Jr., MD ______Children’s Hospital Oakland Research Institute ______Oakland, CA ______Lecturer BIO ______Ervin Epstein, MD, joined CHORI in May, 2007 after 35 years at UCSF. ______He graduated from Harvard College, UCSF Medical School, and received ______his subsequent clinical dermatology and research training at Washington University of St Louis, Harvard, New York University, and the National In- ______stitutes of Health. Since 1972 he has divided his time between independent ______private practice of Dermatology in Oakland and Lafayette and independent research into the molecular bases of skin diseases. He has authored more ______than 100 published papers and, among other organizational posts, has been ______the President of the Society for Investigative Dermatology, the world’s largest ______organization devoted to investigation of the skin and its diseases. He has delivered numerous named award lectureships including those honoring ______Sulzberger (the American Academy of Dermatology) and Dohi (the Japanese ______Dermatologic Association) and was the 2005 recipient of a Lifetime Achieve- ment Award from the American Skin Association. ______

______His current NIH-funded research focuses on non-melanoma skin cancers, ______in particular the commonest human cancer - basal cell carcinomas. He and others identified a crucial molecular abnormality driving the develop- ______ment and maintenance of these tumors a decade ago and subsequently has ______focused on adopting this new information into therapies that someday might make surgical extirpation obsolete. In addition his lab is investigating the cell ______of origin of these tumors, characterizing the cancer stem cells that perpetuate ______their growth, determining why some people are so much more susceptible to ______their growth than are others, even if of the same skin coloration, the role of the immune system in inhibiting their growth, and the development not only ______of new treatments but also of effective preventive approaches. ______AWARD HISTORY The Stephen Rothman Memorial Award is presented annually for distin- ______guished service to investigative cutaneous medicine. The recipient of this ______award has made major scientific achievements and excelled as a teacher ______and recruiter of outstanding dermatologists. The recipient is an individual ______who has distinctly altered the course and image of dermatology or its allied fields. It is the Society’s highest award. ______

45 Open to all meeting attendees CME Credit: .5 ASSOCIATE MEETINGS Herman Beerman Lecture Cancer immunotherapy via blockade of the PD 1 pathway Friday, May 8, 2015

Pediatric Dermatology Research Alliance/ Friday, May 8, 2015 9:45 am - 10:15 am Grand Ballroom, Hilton Atlanta Society for Pediatric Dermatology Session 7:00 am – 8:00 am Room 204-207, Hilton Atlanta

NIAID Symposium 12:00 pm – 1:45 pm Introduction by: S. Wright Caughman, MD Grand Ballroom, Hilton Atlanta

Drew M. Pardoll, MD/PhD Research in Cutaneous Surgery (RCS) Johns Hopkins University School of Medicine Symposium Baltimore, MD 12:00 pm – 1:45 pm Salon A/B, Hilton Atlanta

Lecturer BIO Women’s Dermatologic Society (WDS) Dr. Pardoll holds the Abeloff Professorship in the Department of Oncology of Luncheon Johns Hopkins University School of Medicine. Dr. Pardoll’s interest includes 12:00 pm – 1:45 pm a focus on the regulation of antigen-specific T cell responses and studies ap- Crystal Ballroom, Hilton Atlanta proaches to modify these responses from immunotherapy. North American Hair Research Society (NAHRS)-Scientific Session and Annual Business Meeting 6:00 pm – 9:30 pm Grand Ballroom, Hilton Atlanta

National Psoriasis Foundation (NPF) Scientific Advisory Board Meeting LECTURESHIP HISTORY 6:00 pm – 9:30 pm This award is given in recognition of Dr. Herman Beerman’s long and devoted Room 203, Hilton Atlanta service to the SID and his efforts to secure for it a position of respect in the scientific community. The Herman Beerman Lecture is given by a distinguished National Alopecia Areata Foundation (NAAF) Reception medical scholar at a scientific session of the Society’s Annual Meeting. 6:00 pm – 9:30 pm Traditionally, lecturers from fields other than dermatology are chosen in order to Room 206-207, Hilton Atlanta give meeting attendees the opportunity to learn about scientific advances in other fields. NOTES

NOTES ______

46 Open to all meeting attendees CME Credit: .5 NOTES State-of-the-Art Plenary Lecture 3 ______Translational Research in Vitiligo: Launching a New Era of ______Targeted Treatment ______Friday, May 8, 2015 10:15 am - 10:45 am Grand Ballroom, Hilton Atlanta ______Introduction by: Daniel Kaplan, MD/PhD ______John E. Harris, MD/PhD ______University of Massachusetts Medical School Worcester, MA ______Lecturer BIO Dr. Harris is a tenure-track Assistant Professor in the Dermatology Division, Department of ______Medicine at the University of Massachusetts Medical School (UMMS) in Worcester, MA. Dr. Harris directs the Vitiligo Clinic and Research Center at UMMS, which incorporates a specialty ______clinic for the diagnosis and treatment of patients with vitiligo, as well as a vitiligo research ______laboratory. He uses basic, translational, and clinical research approaches to better understand autoimmunity in vitiligo, with a particular focus on developing more effective treatments. He ______earned his MD and PhD degrees at UMMS, and his PhD was focused on the loss of auto- immune tolerance in juvenile diabetes. He entered a combined research/residency program ______in dermatology at the University of Pennsylvania in Philadelphia, PA, and his post-doctoral research focused on the development of a mouse model of vitiligo with epidermal depigmenta- ______tion. He now advises multiple graduate students, MD/PhD students, and post-doctoral fellows ______in his research laboratory at UMMS, and teaches medical students and residents in his vitiligo clinic. ______NOTES ______

47 Open to all meeting attendees CME Credit: .5 ASSOCIATE MEETINGS State-of-the-Art Plenary Lecture 4 Mitochondria as Signaling Organelles Friday, May 8, 2015

Pediatric Dermatology Research Alliance/ Friday, May 8, 2015 10:45 am - 11:15 am Grand Ballroom, Hilton Atlanta Society for Pediatric Dermatology Session 7:00 am – 8:00 am Room 204-207, Hilton Atlanta

NIAID Symposium 12:00 pm – 1:45 pm Introduction by: Ethan Lerner, MD/PhD Grand Ballroom, Hilton Atlanta

Research in Cutaneous Surgery (RCS) Navdeep S. Chandel, PhD Northwestern University Symposium Chicago, Illinois 12:00 pm – 1:45 pm Salon A/B, Hilton Atlanta Lecturer BIO Navdeep Chandel, the David W. Cugell Professor of Medicine at Northwestern University, Women’s Dermatologic Society (WDS) received a B.A. in mathematics and PhD in Cell Physiology at University of Chicago. He Luncheon also did his post-doctoral work at University of Chicago. In 2000, he established his lab at 12:00 pm – 1:45 pm Northwestern University focusing on the role of mitochondria as signaling organelles. Crystal Ballroom, Hilton Atlanta Historically, mitochondria have been primarily viewed as biosynthetic and bioenergetic organelles. His work has elucidated that mitochondria participate in signaling by releasing North American Hair Research reactive oxygen species which regulate distinct biological outcomes including differentiation, proliferation, and adaptation to stress. Society (NAHRS)-Scientific Session and Annual Business Meeting Dr. Chandel’s research focuses on the mitochondria as signaling organelles. The major 6:00 pm – 9:30 pm function of mitochondria in cellular homeostasis has historically been the generation of Grand Ballroom, Hilton Atlanta through oxidative phosphorylation. However, Dr. Chandel and others have demonstrated that mitochondria can serve as a signaling organelle. The projects in Dr. Chandel’s lab are driven National Psoriasis Foundation (NPF) by the hypothesis that when cells encounter stress the mitochondria serve as key regulators Scientific Advisory Board Meeting of biological outcomes that include the induction of adaptive genes, cellular proliferation, 6:00 pm – 9:30 pm senescence and death. Room 203, Hilton Atlanta

National Alopecia Areata Foundation (NAAF) Reception NOTES 6:00 pm – 9:30 pm ______Room 206-207, Hilton Atlanta ______NOTES

______

48 Open to all meeting attendees CME Credit: 2 NOTES National Institute Of Allergy And Infectious ______Diseases (Niaid)–Symposium ______Understanding Host Defense In Atopic Dermatitis ______Friday, May 8, 2015 12:00 pm – 1:45 pm Grand Ballroom, Hilton Atlanta ______12:00 pm the Role Of The Microbiome In Atopic Dermatitis Richard Gallo, MD/PhD ______University of California-San Diego ______12:25 pm Adaptive Immunity in Atopic Dermatitis and Implications ______for Management of Recurrent ______Donald Leung, MD/PhD National Jewish Health ______

______12:50 pm skin Barrier Defects in Atopic Dermatitis: Prospects for ______Disease Prevention Eric Simpson, MD ______Oregon Health & Sciences University, ______1:15 pm innate Immune Responses in Atopic Dermatitis ______Lisa Beck, MD ______University of Rochester ______1:40 pm Q&A with All Presenters ______NOTES ______

49 Open to all meeting attendees CME Credit: 1 ASSOCIATE MEETINGS Research in Cutaneous Surgery (RCS) Symposium Friday, May 8, 2015

Pediatric Dermatology Research Alliance/ Friday, May 8, 2015 12:00 pm – 1:45 pm Salon A/B, Hilton Atlanta Society for Pediatric Dermatology Session 7:00 am – 8:00 am Room 204-207, Hilton Atlanta

The Research in Cutaneous Surgery (RCS) Symposium is a forum for clinically relevant, patient-directed NIAID Symposium research in dermatologic surgery, including cancer surgery, laser surgery, and cosmetic surgery. With 12:00 pm – 1:45 pm a primary emphasis on clinical research, the symposium aims to highlight clinical trials on procedure Grand Ballroom, Hilton Atlanta safety and effectiveness, as well as epidemiologic investigations. As research in cutaneous surgery is a growing field, the symposium also serves to bring together investigators to facilitate future collaborations. Research in Cutaneous Surgery (RCS) Pilot studies and early work are appropriate for submission. Symposium 12:00 pm – 1:45 pm #338 Microneedle-mediated delivery of vismodegib across skin. Hiep Xuan Nguyen, Ajay K Salon A/B, Hilton Atlanta Banga. Atlanta, GA. Women’s Dermatologic Society (WDS) Luncheon #270 university tort liability for allowing college debit card purchasing of indoor UV tanning. 12:00 pm – 1:45 pm Konstantin Grigoryan, Arthur Best and Robert Dellavalle. Cincinnati, OH and Denver, CO. Crystal Ballroom, Hilton Atlanta

#234 geographically adjusted tool to estimate self-reported cumulative ultraviolet exposure North American Hair Research and associated skin cancer risk. Inbar Raber, Gefei Zhu, Shufeng Li, Sukolsak Society (NAHRS)-Scientific Session and Sakshuwong, Angela Li, Caroline Z Tan and Anne Lynn Su Chang. Redwood City, CA. Annual Business Meeting 6:00 pm – 9:30 pm #223 Photodynamic therapy for benign neurofibromas. Edit B Olasz, Ashley M Schock, Grand Ballroom, Hilton Atlanta Nathan Duncan, Zelmira Lazarova, Suresh Kumar, Brendan Quirk and Harry Whelan. Milwaukee, WI. National Psoriasis Foundation (NPF) Scientific Advisory Board Meeting #210 photodynamic therapy using a white-light LED source is as effective and well-tolerated 6:00 pm – 9:30 pm as daylight photodynamic therapy for the treatment of actinic keratoses, a randomised, Room 203, Hilton Atlanta single-blinded, prospective study. Susan M O’Gorman, Julianne Clowry, MIchael Manley, National Alopecia Areata Jackie McCavana, Linda Gray, Ann Kavanagh, Aoife Lally and Paul Collins. Dublin, Foundation (NAAF) Reception Ireland. 6:00 pm – 9:30 pm Room 206-207, Hilton Atlanta #183 non-invasive imaging technologies for the delineation of basal cell carcinomas. Syril Keena Que. Farmington, CT.

#174 Combined treatment with arsenic trioxide and itraconazole inhibits the hedgehog pathway in patients with refractory metastatic basal cell carcinoma: results from a pilot NOTES trial. Katherine J. Ransohoff, Mina Sarah Ally, Kavita Sarin, Scott Atwood, Melika Rezaee, Irene Bailey, Phillip Beachy, Anne Lynn Su Chang, Anthony Oro, Dimitrios Colevas and ______Jean Y Tang. Stanford, CA. ______

#168 Oral sirolimus improves tuberous sclerosis complex skin tumors without evidence of ______resistance. Neera Nathan, Ji-an Wang, Shaowei Li, Edward West Cowen, Mary Haughey, ______Joel Moss and Thomas N Darling. Bethesda, MD. ______#160 photoaging in African-American skin: A reliable photonumeric scale reveals age, male ______gender, and sun exposure as contributory factors. Anna L. Chien, Ji Qi, Radhika Grandhi, ______Tamia Harris-Tryon, Diane M Kuhn, Min Soo Jang, Noori Kim, Sherry Leung, Jessica Esandrio, Barbara Rainer, Flora Poon, Nancy Cheng, Ginette A Hinds and Sewon Kang. ______Baltimore, MD. ______

#105 Immunosuppression and ethnicity influence keratinocyte differentiation in kidney transplant recipients. Jodi L Johnson, Kathleen J Green, John J. Friedewald and June Robinson. Chicago, IL.

#583 clinicopathological features of Bowen’s disease resistance to methyl aminolevulinate photodynamic therapy. Yolanda Gilaberte, Tamara Gracia-Cazana, Jesus Vera-Alvarez, Angeles Juarranz, Ievgenia Pastushenko, Nerea Salazar, Salvador Gonzalez. 50 Open to all meeting attendees CME Credit: 3 NOTES CONCURRENT MINI-SYMPOSIUM 6 ______CLINICAL RESEARCH (OBSERVATIONS, ______PATHOPHYSIOLOGY & OUTCOMES) ______Friday, May 8, 2015 2:00 pm – 5:00 pm Salon D, Hilton Atlanta ______

______Presiders: Sewon Kang, Md And Stephen Tyring, Md/Phd ______1. Emollient therapy alters skin barrier and microbes in infants at risk for developing atopic ______dermatitis. Martin Glatz, Eric C. Polley, Eric L. Simpson and Heidi H. Kong. Bethesda, MD and Portland, OR. 2:00 pm, Poster #180 ______2. Early pediatric atopic dermatitis shows only a CLA+ Th2/Th1 imbalance, while adults acquire CLA+ Th22 activation. Hitokazu Esaki, Tali Czarnowicki, Juana Gonzalez, Dana Malajian Sreya ______Talasila, Adam Berry, Jayla Gray, Shinji Noda, James Krueger, Amy S. Paller and Emma Guttman- Yassky. New York, NY and Chicago, IL. 2:12 pm, Poster #165 ______3. Throat infections can cause substantial aggravation of chronic plaque psoriasis. Ragna H. Thorleifsdottir, Jenna H. Eysteinsdottir, John H. Olafsson, M I. Sigurdsson, Andrew Johnston, Helgi ______Valdimarsson and Baldur Sigurgeirsson. Uppsala, Sweden; Reykjavik, Iceland and Ann Arbor, MI. 2:24 pm, Poster #175 ______4. Psoriasis area severity index score positively associates with vascular inflammation by FDG PET/CT. Haley B. Naik, Balaji Natarajan, Taufiq Salahuddin, Qimin Ng, Julia Doveikis, Martin ______Playford, Benjamin Lockshin, Mariana Kaplan, Joel Gelfand and Nehal N. Mehta. Bethesda, MD; Silver Spring, MD and Philadelphia, PA. 2:36 pm, Poster #203 ______5. The association between aspirin and NSAIDs with the risk of psoriasis in a population-based cohort. Brandon Cohen, Kathryn J. Martires and Roger Ho. New York, NY. 2:48 pm, ______Poster #211

______6. Shared inflammatory signatures between atherosclerotic plaques and psoriasis skin. William R. ______Swindell, Andrew Johnston, Santhi Ganesh, Katherine Gallagher, Nicole L. Ward, Xianying Xing, Mrinal K. Sarkar, Rajan P. Nair, James T. Elder and Johann E. Gudjonsson. Ann Arbor, MI and ______Cleveland, OH. 3:00 pm, Poster #263

______7. Decreased IL-21 expression in skin and blood contributes to progression of mycosis fungoides. ______Miyoko Kabasawa, Makoto Sugaya, Tomonori Oka, Naomi Takahashi, Makiko Kawaguchi, Hiraku Suga, Tomomitsu Miyagaki, HIdeki Fujita, Yoshihide Asano, Yayoi Tada, Takafumi Kadono and ______Shinichi Sato. Tokyo, Japan. 3:12 pm, Poster #177

______8. Characterizing subsequent malignancies after mycosis fungoides. Kathryn J. Martires, Roger Ho and Jo-Ann Latkowski. New York, NY. 3:24 pm, Poster #237 ______9. Detection of IFN- response induced by infiltrated plasmacytoid dendritic cells and kerati- nocytes via LL37 in the lesional skin of DIHS/DRESS. Pawinee Rerknimitr, Saeko Nakajima, ______Akihiko Kitoh, Yoshiki Miyachi and Kenji Kabashima. Kyoto, Japan and Bangkok, Thailand. 3:36 pm, Poster #206 ______10. Comparisons between ultraviolet B radiation and oral vitamin D supplementation for the treat- ment of vitamin D deficiency. Dong Joo Kim, Jaehwan Kim, Jamie L. Harden, Mary Sullivan- ______Whalen, Patricia Gilleaudeau, Joel M. Corrêa da Rosa, Mayte Suarez-Farinas, Jan Breslow, James Krueger, Michelle Lowes and Manish Ponda. New York, NY; Stony Brook, NY and Bronx, NY. ______3:48 pm, Poster #190 ______11. Identification of two salivary proteins associated with early-stage oral chronic graft-versus-host ______disease. Richard Presland, Wedad Alshehri, Melody Missaghi, Mark Schubert and Michele Lloid. Seattle, WA. 4:00 pm, Poster #173 ______12. Assessment of the genetic basis of rosacea by genome-wide association study. Anne Lynn S. Chang, Inbar Raber, Jin Xu, Rui Li, Robert Spitale, Julia Chen, Amy Kiefer, Chao Tian, Nicholas ______Eriksson, David Hinds and Joyce Tung. Redwood City, CA; Irvine, CA and Mountainview, CA. 4:12 pm, Poster #244

51 Open to all meeting attendees CME Credit: 3 ASSOCIATE MEETINGS CONCURRENT MINI-SYMPOSIUM 7 EPIDERMAL STRUCTURE & BARRIER FUNCTION Friday, May 8, 2015

Pediatric Dermatology Research Alliance/ Friday, May 8, 2015 2:00 pm – 5:00 pm Salon C, Hilton Atlanta Society for Pediatric Dermatology Session 7:00 am – 8:00 am Room 204-207, Hilton Atlanta Presiders: Maria I. Morasso, PhD and Terry Lechler, PhD NIAID Symposium 1. Novel insights in the mechanisms of epidermal maintenance by in vivo imaging. Panteleimon 12:00 pm – 1:45 pm Rompolas and Valentina Greco. New Haven, CT. 2:00 pm, Poster #404 Grand Ballroom, Hilton Atlanta

2. Regulation and disruption of the site-specific skin gene KRT9. Dongwon Kim, M. Zulfiquer Research in Cutaneous Surgery (RCS) Hossain, Ashley Nieves, Lihong Gu, Nicole Yang, Seung Mi Oh, Seunghyun Han, Ji Qi, Janis M. Symposium Taube, Sewon Kang and Luis A. Garza. Baltimore, MD. 2:12 pm, Poster #365 12:00 pm – 1:45 pm Salon A/B, Hilton Atlanta 3. Network analysis identifies MPZL3 as an essential regulator of epidermal differentiation that binds FDXR to induce reactive oxygen species. Aparna Bhaduri, Alexander Ungewickell and Women’s Dermatologic Society (WDS) Paul Khavari. Stanford, CA. 2:24 pm, Poster #341 Luncheon 12:00 pm – 1:45 pm 4. Calmodulin-like 5 interacts with 14-3-3-/stratifin to regulate late epidermal differentiation. Crystal Ballroom, Hilton Atlanta Bryan Sun, Julia Ransohoff, Kun Qu, Vanessa Lopez-Pajares, Lisa D. Boxer and Paul Khavari. Stanford, CA. 2:36 pm, Poster #391 North American Hair Research 5. regulation of protein synthesis during keratinocyte differentiation. Annie E. Collier, Ronald C. Society (NAHRS)-Scientific Session and Wek and Dan F. Spandau. Indianapolis, IN. 2:48 pm, Poster #398 Annual Business Meeting 6:00 pm – 9:30 pm 6. A reinnervated skin model: A new tool to study link between innervation and aging. Christine Grand Ballroom, Hilton Atlanta Jeanmaire, Carine Tedeschi, Manasi Chavan, Laurent Misery and Nicolas Lebonvallet. Essey les Nancy, France and Brest, France. 3:00 pm, Poster #336 National Psoriasis Foundation (NPF) Scientific Advisory Board Meeting 7. Tight junction barrier dysfunction induced by epidermis-specific claudin-1 ablation is sufficient 6:00 pm – 9:30 pm to cause dermatitis in mice. Akiharu Kubo, Takashige Hirano, Mariko Yokouchi, Hiroshi Room 203, Hilton Atlanta Kawasaki, Toru Atsugi and Masayuki Amagai. Tokyo, Japan and Kyoto, Japan. 3:12 pm, Poster #352 National Alopecia Areata 8. Histamine impairs keratinocyte barrier function. Anna De Benedetto, Takeshi Yoshida, Sade Foundation (NAAF) Reception Fridy, Joo-Eun S. Park and Lisa A. Beck. Rochester, NY. 3:24 pm, Poster #346 6:00 pm – 9:30 pm Room 206-207, Hilton Atlanta 9. Epidermal SIRT1 loss disrupts skin barrier integrity and sensitizes mice to epicutaneous allergen challenge. Mei Ming, Baozhong Zhao, Christopher R. Shea, Shah Palak, Lei Qiang, Steven R. White, Diane Sims and Yu-Ying He. Chicago, IL. 3:36 pm, Poster #347

10. The role of TGF- signaling-mediated miR-486-3p on the inhibition of keratin 17 in the NOTES pathogenesis of psoriasis. Man Jiang, Zhongbin Sun, Lin Gao and Gang Wang. Xi’an, China and Urumuqi, China. 3:48 pm, Poster #383 ______

11. Topoisomerase 2 impacts gene-length bias in psoriasis through altered epidermal differentia- ______tion. Mrinal K. Sarkar, Andrew Johnston, William R. Swindell, Xianying Xing, Ariel Finkielsztein, Spiro Getsios and Johann E. Gudjonsson. Ann Arbor, MI and Chicago, IL. 4:00 pm, Poster #399 ______12. X-ray crystal structure of the keratin 1–keratin 10 heterodimer reveals a molecular basis for associated keratinopathies. Christopher G. Bunick. New Haven, CT. 4:12 pm, Poster #349 ______

52 Open to all meeting attendees CME Credit: 3 NOTES

______CONCURRENT MINI-SYMPOSIUM 8 ______GENETIC DISEASE & GENE REGULATION ______Friday, May 8, 2015 2:00 pm – 5:00 pm Room 204-207, Hilton Atlanta ______Presiders: Amy Paller, MD/MS and Eli Sprecher, MD/PhD

______1. DDX6 orchestrates human epidermal progenitor function through the mRNA degradation and ______translation pathways. George Sen, Ying Wang and Yifang Chen. La Jolla, CA. 2:00 pm, Poster #430 ______2. Gasdermin A3 targets mitochondria to mediate keratinocyte necrosis and skin inflammation. ______Pei-Husan Lin, Hsien-Yi Lin, Shu-Hui Wu, Cheng-Chin Kuo and Liang-Tung Yang. Zhunan, Taiwan and Taichung, Taiwan. 2:12 pm, Poster #437 ______3. The BAF/SWI/SNF complex controls genome accessibility to p63 during epidermal differentiation. Xiaomin Bao, Adam Rubin, Kun Qu, Jiajing Zhang, Paul Giresi, Howard Chang ______and Paul Khavari. Stanford, CA and Palo Alto, CA. 2:24 pm, Poster #451 ______4. Functional genomics of the ULBP6 locus reveals a critical role for CTCF-mediated long-range ______interactions in alopecia areata. Gina M. DeStefano, Lynn Petukhova, Esther Drill, Zhenpeng Dai, Li Bian, Raphael Clynes and Angela Christiano. New York, NY. 2:36 pm, Poster #448 ______5. Somatic activating RAS mutations cause vascular tumors including pyogenic granuloma. Young ______H. Lim, Stephanie Douglas, Christine J. Ko, Richard Antaya, Jennifer McNiff, Jing Zhou, Richard ______P. Lifton, Deepak Narayan and Keith A. Choate. New Haven, CT. 2:48 pm, Poster #436

______6. Analysis of long non-coding RNAs highlights tissue-specific expression patterns and epigenetic profiles in normal and psoriatic skin. James T. Elder, Lam C. Tsoi, Matthew K. Iyer, Philip E. ______Stuart, William R. Swindell, Johann E. Gudjonsson, Trilokraj Tejasvi, Mrinal K. Sarkar, Bingshan ______Li, Jun Ding, John J. Voorhees, Hyun M. Kang, Rajan P. Nair, Arul M. Chinnaiyan and Goncalo Abecasis. Ann Arbor, MI; Nashville, TN and Bethesda, MD. 3:00 pm, Poster #440 ______7. MCP-1 is overexpressed by Tsc2-null skin fibroblasts in a mouse model of tuberous sclerosis ______with targeted disruption of Tsc2. Shaowei Li, Peter Klover, Rajesh L. Thangapazham, Ji-an Wang, ______Joel Moss and Thomas N. Darling. Bethesda, MD. 3:12 pm, Poster #441 ______8. Dominant de novo GJA1 mutations cause erythrokeratodermia variabilis. Lynn Boyden, Brittany Craiglow, Jing Zhou, Ronghua Hu, Erin Loring, Kimberly Morel, Christine Lauren, Richard Lifton, ______Amy Paller and Keith Choate. New Haven, CT; New York, NY and Chicago, IL. 3:24 pm, ______Poster #444 ______9. Onychodystrophy, Palmoplantar keratoderma, and Amelogenesis imperfecta (OPA) syndrome caused by a homozygous mutation in CNBD2. YC Metzger, O. Sarig, R. Bochner, D. Vodo, N ______Malchin, O. Isakov, N. Erez, A. Gat, I. Goldberg, N. Shomron, M. Schwartz, WHI Mclean, FJD ______Smith, FB Rihani and E. Sprecher. Tel Aviv, Israel; Dundee, United Kingdom; Salt Lake City, UT and Irbid, Jordan. 3:36 pm, Poster #450 ______10. The lncRNA FLJ46906 alters expression of aging-associated proteins through binding to AP-1 ______and NF-B. Kazuyuki Yo and Thomas M. Ruenger. Providence, RI and Yokohama, Japan. ______3:48 pm, Poster #434 ______11. Novel regulatory variants identified in adult atopic dermatitis by targeted deep sequencing alter enhancer function. Ashley Quiggle, Twinkal Marfatia, Kara J. Gulewicz, Avner Shemer, Zane ______Goodwin, Wendell Jones, Emma Guttman-Yassky and Cristina de Guzman Strong. St. Louis, MO; Tel-Aviv, Israel and New York, NY. 4:00 pm, Poster #452 ______12. Trans-ethnic genome-wide meta-analysis identifies multiple novel associations and reveals ethnic heterogeneity of psoriasis susceptibility. Xianyong Yin, Hui QI Low, Mark Seielstad, ______Wilson Liao, Mona Ståhle, Andre Franke, Xuejun Zhang and Jianjun Liu. Singapore, Singapore; San Francisco, CA; Stockholm, Sweden; Kiel, Germany and Hefei, China. 4:12 pm, Poster #431 ______

53 Open to all meeting attendees CME Credit: 3 ASSOCIATE MEETINGS CONCURRENT MINI-SYMPOSIUM 9 INNATE IMMUNITY, INFLAMMATION & MICROBIOLOGY Friday, May 8, 2015

Pediatric Dermatology Research Alliance/ Friday, May 8, 2015 2:00 pm – 5:00 pm Salon E, Hilton Atlanta Society for Pediatric Dermatology Session 7:00 am – 8:00 am Room 204-207, Hilton Atlanta

NIAID Symposium Presiders: Lloyd Miller, MD/PhD and Anna Di Nardo, MD/PhD 12:00 pm – 1:45 pm Grand Ballroom, Hilton Atlanta 1. Spatial expression of RGD-binding integrins on keratinocytes control homeostatic and UV-induced Langerhans cell migration by activating latent TGF. Javed Mohammed, Aleh Bobr, Brian Astry, Alina G. Bridges and Daniel Kaplan. Minneapolis, MN and Rochester, MN. Research in Cutaneous Surgery (RCS) 2:00 pm, Poster #557 Symposium 12:00 pm – 1:45 pm 2. Dermal adipocytes protect against invasive Staphylococcus aureus skin . Lingjuan Salon A/B, Hilton Atlanta Zhang, Christian F. Guerrero-Juarez, Tissa Hata, Raul Ramos, Maksim Plikus and Richard L. Gallo. San Diego, CA and Irvine, CA. 2:12 pm, Poster #522 Women’s Dermatologic Society (WDS) Luncheon fl/fl 3. Dysbiotic microbiota drives atopic inflammation in Adam17 Sox9-Cre mice. 12:00 pm – 1:45 pm Tetsuro Kobayashi, Martin Glatz, Keisuke Horiuchi, Thomas Doebel, Daniel Kaplan, Heidi H. Crystal Ballroom, Hilton Atlanta Kong, Masayuki Amagai and Keisuke Nagao. Tokyo, Japan; Bethesda, MD and Minneapolis, MN. 2:24 pm, Poster #508 North American Hair Research Society (NAHRS)-Scientific Session and 4. Nociceptive sensory fibers drive IL-23 from CD301b+ dermal DC and provide protection from cutaneous C. albicans infection. Sakeen W. Kashem and Daniel Kaplan. Minneapolis, MN. Annual Business Meeting 2:36 pm, Poster #521 6:00 pm – 9:30 pm Grand Ballroom, Hilton Atlanta 5. TLR4 acts as a death receptor for ultraviolet radiation (UVR) in antigen presenting cells. Hua Zhou, Erin Harberts, Rita Fishelevich, Stefanie Vogel and Anthony Gaspari. Baltimore, MD. National Psoriasis Foundation (NPF) 2:48 pm, Poster #524 Scientific Advisory Board Meeting 6:00 pm – 9:30 pm 6. Cell-specific inflammatory response to short-chain fatty acids produced by P. acnes. James A. Room 203, Hilton Atlanta Sanford and Richard L. Gallo. San Diego, CA. 3:00 pm, Poster #543 National Alopecia Areata 7. IL-1-independent neutrophil recruitment induces long-term protection against a Foundation (NAAF) Reception Staphylococcus aureus skin reinfection. Carly Page, Da Lee, Yu Wang, Jonathan Shahbazian, 6:00 pm – 9:30 pm Alyssa Ashbaugh and Lloyd Miller. Baltimore, MD. 3:12 pm, Poster #509 Room 206-207, Hilton Atlanta 8. The human skin virome and its interactions with the host microbiome. Geoffrey D. Hannigan, Jacquelyn Meisel, Amanda Tyldsley, Qi Zheng, Brendan P. Hodkinson, Adam J. SanMiguel, Samu- el Minot, Frederic D. Bushman and Elizabeth A. Grice. Philadelphia, PA. 3:24 pm, Poster #553

9. IL-1 and IL-36 are the dominant cytokines in generalized pustular psoriasis. Andrew Johnston, NOTES Xianying Xing, Liza Wolterink, Drew H. Barnes, William R. Swindell, Mrinal K. Sarkar, J M. Kahlenberg, Paul W. Harms and Johann E. Gudjonsson. Ann Arbor, MI. 3:36 pm, Poster #552 ______

10. Angiogenic peptide-30 (AG-30) activates primary human keratinocytes to produce cytokines/ ______chemokines via MrgX receptors. Chanisa Kiatsurayanon, Francois Niyonsaba, Hiroko Ushio, ______Shigaku Ikeda, Ko Okumura and Hideoki Ogawa. Tokyo, Japan. 3:48 pm, Poster #526 ______11. PD-1 regulates imiquimod-induced psoriasiform dermatitis through inhibition of innate IL-17A expression by  low T Cells. Yasutomo Imai, Xuesong Wu, Natarajan Ayithan, Li Wang and Sam ______Hwang. Milwaukee, WI. 4:00 pm, Poster #544 ______12. LTA from commensal bacteria modulates keratinocyte SCF production to maintain mast cells in ______the skin. Zhenping Wang, Xiaojun Sun and Anna Di Nardo. La Jolla, CA. 4:12 pm, Poster #560 ______

54 Open to all meeting attendees CME Credit: 3 NOTES CONCURRENT MINI-SYMPOSIUM 10 ______PIGMENTATION & MELANOMA ______Friday, May 8, 2015 2:00 pm – 5:00 pm Salon A/B, Hilton Atlanta ______Presiders: Brian Pollack, MD/PhD and Andrej T. Slominski, MD/PhD

______1. Deregulation of chemotactic signals, leukocyte recruitment, and immunity in segmental vitiligo. Moetaz El-Domyati, Wael Hosam El-Din, Ahmed Fawzy Rezk, Jouni Uitto, Olga Igoucheva and ______Vitali Alexeev. Minia, Egypt and Philadelphia, PA. 2:00 pm, Poster #652 ______2. CD4, IL-17, and COX-2 are associated with inflammation in melisma. Adriana Rodríguez- ______Arámbula, Juan P. Castanedo-Cázares, Diego Cortés-García, Bertha Torres-Álvarez and Karla I. Martínez-Rosales. San Luis Potosi, Mexico. 2:12 pm, Poster #615 ______3. Delayed cyclobutane pyrimidine dimers induced by chemiexcited melanin derivatives long after UV exposure. Sanjay Premi, Silvia Wallisch, Camila Mano, Adam Weiner, Antonella ______Bacchiocchi, Kazumasa Wakamatsu, Etelvino Bechara, Ruth Halaban, Thierry Douki and Douglas E. Brash. New Haven, CT; Sao Paulo, Brazil; Toyoake, Japan and Grenoble, France. ______2:24 pm, Poster #635 ______4. Y chromosome encoded TSPY proto- drives increased melanoma cell ______aggressiveness. Zhi-ming Huang, Yunmin Li, Tatsuo Kido, Iwei Yeh, Kavari Korgavkar, Adi Nosrati, John Livingstone, Jillian W. Wong, Glynis Scott, Chris Lau and Maria L. Wei. San ______Francisco, CA and Rochester, NY. 2:36 pm, Poster #622 ______5. Sex steroids regulate human pigmentation through non-classical receptors. Christopher Natale ______and Todd W. Ridky. Philadelphia, PA. 2:48 pm, Poster #637

______6. MSX1-induced neural crest-like reprograming promotes melanoma progression. Mizuho ______Fukunaga-Kalabis, Markus Heppt, Joshua Wang, Denitsa Hristova, Zhi Wei, Martin Irmler, Carola Berking, Robert Besch, Johannes Beckers, Frank J. Rauscher, David E. Fisher and Meenhard Her- ______lyn. Philadelphia, PA; Munich, Germany; Newark, NJ; Neuherberg, Germany and Boston, MA. 3:00 pm, Poster #646 ______7. Multigene epigenetic signature is a prognostic marker in melanoma. Goran Micevic, Viswanathan Muthusamy, Richard Scolyer and Marcus Bosenberg. New Haven, CT and ______Sydney, Australia. 3:12 pm, Poster #634

______8. Oncogene starvation via selective CDK7 inhibition: A novel approach for targeting traditionally ______undruggable oncogenic molecules in melanoma. Philip Eliades, David M. Miller, Michael Taylor, Raj Kumar, Nicholas Kwiatkowski, Tinghu Zhang, Richard A. Young, Nathanael S. Gray and ______Hensin Tsao. Boston, MA and Cambridge, MA. 3:24 pm, Poster #636

______9. IL-23 prevents melanoma development through multiple mechanisms. Tahseen H. Nasti, ______Mohammad Athar, Laura Timares and Craig Elmets. Birmingham, AL. 3:36 pm, Poster #651 ______10. CDK1 enhances tumor initiation and stemness by interacting with stem cell genes in human cancers. Yuchun Luo, John J. Arcaroli, Nicholas Nguyen, Sucai Liu, Lekha Kutty, Stacey Bagby, ______Steven Robinson, William Robinson, David Norris, Wells Messersmith and Mayumi Fujita. Aurora, CO and Denver, CO. 3:48 pm, Poster #624 ______11. MT19c resensitizes metastatic melanoma cells to vemurafenib, decreases tumor growth, and increases survival in a vemurafenib-resistant metastatic melanoma model. Alex Han, Michael ______Vezeridis, Rakesh Singh, Leslie Robinson-Bostom, Martin Weinstock and Richard Moore. Providence, RI. 4:00 pm, Poster #617 ______12. Inhibition of histone deacetylase 3 overcomes BRAF-inhibitor resistance. Xiao-Qi Wang, Antonio Velez, Chelsea St. Claire and Amy S. Paller. Chicago, IL. 4:12 pm, Poster #644 ______

55 Open to all meeting attendees CME Credit: 3 ASSOCIATE MEETINGS CONCURRENT MINI-SYMPOSIUM 11 INTERDISCIPLINARY SPOTLIGHT: SKIN CANCER Friday, May 8, 2015

Pediatric Dermatology Research Alliance/ Friday, May 8, 2015 2:00 pm – 5:00 pm Grand Ballroom, Hilton Atlanta Society for Pediatric Dermatology Session 7:00 am – 8:00 am Room 204-207, Hilton Atlanta Presiders: Paul Khavari, MD/PhD and Andrew South, PhD NIAID Symposium 1. The role of dermal wnt activation in hair follicle development and carcinogenesis. Peggy 12:00 pm – 1:45 pm Myung, Thomas Yang, Panteleimon Rompolas and Valentina Greco. New Haven, CT. 2:00 pm, Grand Ballroom, Hilton Atlanta Poster #674 Research in Cutaneous Surgery (RCS) 2. Drinking green tea inhibits photocarcinogenesis in mice by upregulating the levels of miRNA-29 Symposium and subsequently inhibition of DNA hypermethylation in tumors. Santosh K. Katiyar, Tripti 12:00 pm – 1:45 pm Singh and Ram Prasad. Birmingham, AL. 2:12 pm, Poster #579 Salon A/B, Hilton Atlanta

3. miR-30 is downregulated in human squamous cell carcinoma and UVB exposed keratinocytes. Women’s Dermatologic Society (WDS) Deeba N. Syed, Rahul K. Lall, Nosheen Akhtar, Jack Longley and Hasan Mukhtar. Madison, WI. Luncheon 2:24 pm, Poster #598 12:00 pm – 1:45 pm Crystal Ballroom, Hilton Atlanta 4. Fibulin-4 is down-regulated in malignant head and neck SCC. Kathleen P. McGuinn, Takako Sasaki, Mon Li Chu and My G. Mahoney. Philadelphia, PA and Oita, Japan. 2:36 pm, Poster #502 North American Hair Research Society (NAHRS)-Scientific Session and 5. Differential requirement for HB-EGF vs. amphiregulin for survival of malignant vs. normal Annual Business Meeting epithelial cells. Stefan W. Stoll and James T. Elder. Ann Arbor, MI. 2:48 pm, Poster #489 6:00 pm – 9:30 pm Grand Ballroom, Hilton Atlanta 6. Rolling the genetic dice: Neutral and deleterious SMO mutations in drug-resistant basal cell carcinoma. Scott Atwood, Kavita Sarin, Jiang Li, Catherine Yao, Nicole M. Urman, Anne Lynn S. National Psoriasis Foundation (NPF) Chang, Jean Y. Tang and Anthony Oro. Stanford, CA. 3:00 pm, Poster #120 Scientific Advisory Board Meeting 6:00 pm – 9:30 pm 7. Basal cell carcinoma originates from multiple stem cell lineages within hair follicle and Room 203, Hilton Atlanta mechanosensory touch dome epithelia. Shelby C. Peterson, Andrzej Dlugosz and Sunny Wong. Ann Arbor, MI. 3:12 pm, Poster #111 National Alopecia Areata 8. Genomic drivers of cutaneous squamous cell carcinoma development. Vida Chitsazzadeh, C. Foundation (NAAF) Reception Coarfa, T. Nguyen, A. K. Joseph, P. Gunaratne, X. Su, D. A. Wheeler, E. R. Flores and Kenneth 6:00 pm – 9:30 pm Tsai. Houston, TX and Pasadena, TX. 3:24 pm, Poster #110 Room 206-207, Hilton Atlanta

9. Alcohol consumption and risk of cutaneous basal cell carcinoma in women and men. Shaowei Wu, Wen-Qing Li, Abrar A. Qureshi and Eunyoung Cho. Providence, RI. 3:36 pm, Poster #323

10. The risk of cancer in patients with psoriasis: A population-based cohort study in the United NOTES Kingdom. Zelma C. Chiesa, Daniel B. Shin, Junko Takeshita, Alexis Ogdie and Joel Gelfand. Philadelphia, PA. 3:48 pm, Poster #302 ______

11. Intrinsic resistance to smoothened inhibitors in sporadic basal cell carcinoma. Prajakta Jaju, ______Melika Rezaee, Alexander Lee, Jean Y. Tang and Kavita Sarin. Stanford, CA. 4:00 pm, Poster #425 ______12. Non-melanoma skin cancers are associated with blood expansion of DC-HIL+ myeloid-derived suppressor cells (MDSC). Andrew P. Word, Jin-Sung Chung, Travis Vandergriff, David B. Harker, ______Kiyoshi Ariizumi and Ponciano D. Cruz. Dallas, TX. 4:12 pm, Poster #199 ______

56 Open to all meeting attendees CME Credit: 0 NOTES

______MINI-SYMPOSIA MIXERS ______Friday, May 8, 2015 5:00 pm – 6:00 pm Individual Concurrent Meeting Rooms ______H hilton Atlanta ______Immediately following the afternoon Concurrent Minisymposia Sessions (Thursday and Friday only), a ______45-minute mixer will be held. Presenters, moderators and attendees will be able to interact as they enjoy ______light refreshments and snacks. These mixers are designed to encourage informal discussion, mingling ______and networking among SID meeting attendees. ______NOTES ______

57 Open to all meeting attendees CME Credit: 0 ASSOCIATE MEETINGS North American Hair Research Society Friday, May 8, 2015 Scientific Meeting Pediatric Dermatology Research Alliance/ Society for Pediatric Dermatology Session 7:00 am – 8:00 am Friday, May 8, 2015 6:00 pm – 9:30 pm Grand Ballroom, Hilton Atlanta Room 204-207, Hilton Atlanta NIAID Symposium 12:00 pm – 1:45 pm 6:00 pm Poster Viewing & Reception Grand Ballroom, Hilton Atlanta 1. Subcutaneous abatacept in the treatment of moderate to severe alopecia areata. Julian Mackay-Wiggan, Nhan M. Nguyen, Charlotte Clark, Ali Jabbari, Grace Ulerio, Megan Furniss, Research in Cutaneous Surgery (RCS) Raphael Clynes, Angela Christiano. Poster #238 Symposium 12:00 pm – 1:45 pm 2. Characterization of biomarker signatures in cross-sectional and Salon A/B, Hilton Atlanta longitudinal studies for use as an Alopecia Areata Disease Activity Index (ALADIN). Jane E. Cerise, Ali Jabbari, Madeleine Duvic, Maria Hordinsky, David Norris, Vera H. Price, Julian Women’s Dermatologic Society (WDS) Mackay-Wiggan, Raphael Clynes, Angela Christiano. Poster #264 Luncheon 12:00 pm – 1:45 pm 3. Lymphatic vessel endothelial hyaluronan receptor-1 (LYVE-1) expression is similar in normal Crystal Ballroom, Hilton Atlanta human parietal and occipital scalp. Brooke Hanson, Melissa Weber-Sanders, James Hodges, Heather Bemmels, Maria Hordinsky, Marna Ericson. Poster #277 North American Hair Research Society (NAHRS)-Scientific Session and 4. Multiple facial vellus hair cysts, ear pits, lipomas, macrocephaly, joint laxity and cardiac defects: A novel genodermatosis? Marisa Grace G. Ponzo, Margot Van Allen, Magdalena Annual Business Meeting Martinka, Jan P. Dutz. Poster #449 6:00 pm – 9:30 pm Grand Ballroom, Hilton Atlanta 5. Low-level laser treatment of chemotherapy-induced alopecia: A preclinical study in rats. Assuan Lens, Keyvan Nouri, Joaquin Jimenez, Tongyu C. Wikramanayake. Poster #610 National Psoriasis Foundation (NPF) Scientific Advisory Board Meeting 6. Knockdown of Sulf2 causes hair loss in obese mice fed a fast food diet. Jeannette M. 6:00 pm – 9:30 pm Olazagasti, Catherine D. Moser, Tae H. Kim, Anuradha Krishnan, Lewis R. Roberts. Room 203, Hilton Atlanta Poster #658 National Alopecia Areata 7. Alterations of vitamin A metabolism and signaling in central, centrifugal, cicatricial alopecia Foundation (NAAF) Reception patients. Liye Suo, Wilma F. Bergfeld, Natasha Mesinkovska, Helen B. Everts. Poster #665 6:00 pm – 9:30 pm 8. Preventing radiation-induced hair loss by augmenting spontaneous anagen repair through Room 206-207, Hilton Atlanta modulating wnt signaling. Wen-Yen Huang, Hsien-Yi Chiu, Chih-Chieh Chan, Sung-Jan Lin. Poster #670

9. Novel diagnostic test predicts mean change in hair counts in female androgenetic alope- cia patients treated with topical minoxidil. John McCoy, Andy Goren, Janet Roberts, Nisha NOTES Desai. Poster #672 ______10. Enhancing hair follicle regeneration by microthermal injury. Yueh-Feng Wu, Sabrina Mai-Yi Fan, Sung-Jan Lin. Poster #676 ______11. Apoptotic signals increase during catagen-like changes in hair follicles confirming follicle organ culture’s exciting new potential as a human in vitro catagen model. Heero N. ______Rahman, Nilofer Farjo, Bessam Farjo, Valerie Randall. Poster #677 ______12. Prostaglandin D2 (PGD2) enhances testosterone metabolism in primary human keratino- ______cytes possibly via upregulation of aldo-keto reductase 1C3 (AKR1C3) expression. Alon Mantel, Alice P. Pentland, Meena Katdare. Poster #684 ______Continued on Next Page ______

58 NOTES Continued ______North American Hair Research Society Scientific Meeting

______6:45 pm Keynote Speaker ______wnt/beta-catenin signaling regulates proliferation but not survival of hair follicle pro- genitor cells ______Sarah E. Millar, PhD Professor, Departments of Dermatology and Cell & Developmental Biology, ______Director of Research, ______Department of Dermatology, University of Pennsylvania

______7:15 pm Keynote Speaker ______Genetics and Immunology of Alopecia Areata Angela M. Christiano, PhD ______Professor of Dermatology and Genetics & Development, Columbia University

______7:45 pm Oral Presentations 12 minutes for presentation + 3 minutes for Q&A and change of speaker ______1. 7:45 pm ______Oral ruxolitinib induces hair regrowth in moderate to severe alopecia areata. Julian Mackay-Wiggan, Nhan M. Nguyen, Charlotte Clark, Ali Jabbari, Grace Ulerio, Me- ______gan Furniss, Raphael Clynes, Angela Christiano. Poster #272 ______2. 8:00 pm ______IFN- pathway blockade prevents the onset of alopecia areata. Raphael Clynes, Zhen- peng Dai, Luzhou Xing, Ali Jabbari, Angela Christiano. Poster #090 ______3. 8:15 pm Expression of a novel immunoglobulin protein in the skin and other epithelia. Hunter ______Mitchell, Tongyu C. Wikramanayake. Poster #370

______4. 8:30 pm ______Human hair follicle epithelial stem cells undergo epithelial-mesenchymal transition (EMT) in primary cicatricial alopecia: Lessons from lichen planopilaris. Hisayoshi ______Imanishi, David Ansell, Matthew Harries, Norbert Sepp, Tamas Biro, Daisuke Tsuruta, Christopher M. Ward, Ralf Paus. Poster #666 ______8:45pm nAHRS Updates and Announcements ______NOTES ______59 TICKETED EVENT; PRE-REGISTRATION IS REQUIRED CME Credit: 0 ASSOCIATE MEETINGS TRAINEE DINNER Friday, May 8, 2015

Pediatric Dermatology Research Alliance/ Friday, May 8, 2015 7:00 pm – 9:00 pm Crystal Ballroom, Hilton Atlanta Society for Pediatric Dermatology Session 7:00 am – 8:00 am Room 204-207, Hilton Atlanta

TICKETED EVENT; PRE-REGISTRATION IS REQUIRED NIAID Symposium 12:00 pm – 1:45 pm Throughout the years, the SID has encouraged meetings between Residents and Post-Doc Fellows. To Grand Ballroom, Hilton Atlanta continue its promotion of collegiality, the SID presents a Trainee Dinner – small group meetings in which Research in Cutaneous Surgery (RCS) senior and junior scientists and a group of four to six residents and post-doc fellows – discuss issues over Symposium dinner. These sessions provide an opportunity to talk informally about subject matter of interest including 12:00 pm – 1:45 pm Salon A/B, Hilton Atlanta research opportunities in dermatology, life in academia or how to combine clinical work with research. Women’s Dermatologic Society (WDS) Luncheon 12:00 pm – 1:45 pm Crystal Ballroom, Hilton Atlanta

North American Hair Research Society (NAHRS)-Scientific Session and Annual Business Meeting 6:00 pm – 9:30 pm NOTES Grand Ballroom, Hilton Atlanta ______National Psoriasis Foundation (NPF) ______Scientific Advisory Board Meeting ______6:00 pm – 9:30 pm ______Room 203, Hilton Atlanta ______National Alopecia Areata Foundation (NAAF) Reception ______6:00 pm – 9:30 pm ______Room 206-207, Hilton Atlanta ______NOTES ______

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61 Saturday, May 9 issue Regeneration & issue Regeneration T Meeting-at-a-Glance Plenary Session III Montagna Lecture William Stone Lecture Julius Session II Program Clinical Scholars Vaccination Immunity & Adaptive Concurrent Mini-Symposium 12: & Adhesion Cell Factors, Concurrent Mini-Symposium 13: Growth Matrix Biology Concurrent Mini-Symposium 14: Photobiology Concurrent Mini-Symposium 15: Healing Wound Dermatology International Societies for Investigative (ISID) Informational Meeting

61 62 63 64 65 66 67 68 60 Saturday Sessions Saturday PAGE E titl

ASSOCIATE Meeting-At-A-Glance MEETINGS

Saturday, May 9, 2015 Saturday, May 9, 2015 ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– International Societies for Investigative SID Board of Directors Meeting 7:00 am – 7:45 am Dermatology (ISID) Informational Meeting Crystal Ballroom, Hilton Atlanta 2:00 pm – 3:30 pm ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Crystal Ballroom, Hilton Atlanta Registration 7:30 am – 12:00 pm Convention Registration Area, First Floor, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Plenary Session III 8:00 am – 9:00 am Grand Ballroom, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– William Montagna Lecture 9:00 am – 9:30 am Therapeutic Target Practice in Melanoma Hensin Tsao, MD/PhD Grand Ballroom, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Julius Stone Lecture 9:30 am – 10:00 am The Multifaceted Immunoregulatory Functions of the PD-1 pathway Arlene H. Sharpe, MD/PhD Grand Ballroom, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Poster Session III 10:00 am – 12:00 pm Poster #’s 247-489 Odd & #’s 492-736 Even Galleria Exhibit Hall, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Clinical Scholars Program Session II 10:15 am – 12:15 pm Grand Ballroom, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Concurrent Mini-symposia 12:30 pm – 3:30 pm Adaptive Immunity & Vaccination Salon D, Hilton Atlanta Growth Factors, Cell Adhesion & Matrix Biology Salon A/B, Hilton Atlanta Photobiology Salon C, Hilton Atlanta tissue Regeneration & Wound Healing Salon E, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– International Societies for Investigative 2:00 pm – 3:30 pm Dermatology (ISID) Informational Meeting Crystal Ballroom, Hilton Atlanta ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– NOTES

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62 Open to all meeting attendees CME Credit: .5 NOTES PLENARY SESSION III ______Presiders: Sam Hwang, MD/PhD and Sarah Millar, PhD ______Saturday, May 9, 2015 8:00 am - 9:00 am Grand Ballroom, Hilton Atlanta ______1. Psoriasis drug development and GWAS interpretation through in silico analysis of transcription factor binding sites. William R. Swindell, Mrinal K. Sarkar, Philip E. Stuart, John J. Voorhees, ______James T. Elder, Andrew Johnston and Johann E. Gudjonsson. Ann Arbor, MI. 8:00 am, ______Poster #446 ______2. Narrow band UVB treatment of human vitiligo is associated with induction of stem cell genes ______for melanocyte repopulation in the hair follicle and epidermis. Nathaniel B. Goldstein, Maranke ______I. Koster, Laura Hoaglin, Bifeng Gao, Kenneth Jones, Dennis R. Roop, David Norris and Stanca A. Birlea. Aurora, CO. 8:12 am, Poster #641 ______3. IL-17C, TNF and IL-36 compensate for loss of IL-6 and identify novel signals facilitating the transition between uninvolved and involved psoriasis skin. Philip Klenotic, Andrew Johnston, ______Thomas McCormick and Nicole L. Ward. Cleveland, OH and Ann Arbor, MI. 8:24 am, ______Poster #530 ______4. Integrin v is necessary for skin tissue generation and SCC tumor invasion, but is dispensable ______for epidermal maintenance. Elizabeth K. Duperret and Todd W. Ridky. Philadelphia, PA. ______8:36 am, Poster #474

______5. Characterization of lipoprotein composition and function in pediatric psoriasis reveals a more ______atherogenic profile. Wynnis Tom, Lawrence F. Eichenfield, Martin Playford, Shehla Admani, Balaji Natarajan and Nehal N. Mehta. San Diego, CA and Bethesda, MD. 8:48 am, Poster #219 ______NOTES ______

63 Open to all meeting attendees CME Credit: .5 ASSOCIATE MEETINGS William Montagna Lecture Therapeutic Target Practice in Melanoma Saturday, May 9, 2015

International Societies for Investigative Dermatology (ISID) Informational Meeting Saturday, May 9, 2015 9:00 am – 9:30 am Grand Ballroom, Hilton Atlanta 2:00 pm – 3:30 pm Crystal Ballroom, Hilton Atlanta

Introduction by: Anthony Gaspari, MD

Hensin Tsao, MD/PhD Massachusetts General Hospital Boston, MA

Dr. Hensin Tsao is Professor of Dermatology at Harvard Medical School and serves as the Director of both the MGH Melanoma and Pigmented Lesion Center and the MGH Melanoma Genetics Program. He is also the Head of the Skin Cancer Genetics Laboratory in the Wellman Center for Photomedi- cine at MGH where he oversees a research program in melanoma genetics and therapeutics. Dr. Tsao graduated Magna Cum Laude and Phi Beta Kappa from Brown University with a degree in Biochemistry and English. In 1993, he graduated Alpha Omega Alpha from the Columbia University College of Phy- sicians and Surgeons with an MD degree and Columbia University Graduate School of Arts of Sciences with a PhD degree in Biophysics/Biochemistry.

LECTURESHIP______HISTORY The William Montagna Lecture is given annually at the Society’s Annual Meeting. This award is intended to honor and reward young active investigators. Primary emphasis is given to researchers in skin biology. NOTES

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64 Open to all meeting attendees CME Credit: 1 NOTES Julius Stone Lecture ______The Multifaceted Immunoregulatory Functions of the PD-1 pathway ______Saturday, May 9, 2015 9:30 am – 10:00 am Grand Ballroom, Hilton Atlanta ______Introduction by: My Mahoney, PhD ______Arlene H. Sharpe, MD/PhD ______Harvard Medical School ______Boston, MA

______Dr. Sharpe is the George Fabyan Professor of Comparative Pathology, ______Department of Microbiology and Immunobiology, Harvard Medical School. Her research is focused on understanding the role of costimulatory molecules ______in T cell activation in vivo. ______

______LECTURESHIP HISTORY ______The Julius Stone Lectureship is intended to promote the advancement of knowl- edge in immunology as it relates to the skin and skin disease. The Lectureship is ______intended to honor Dr. Julius Stone, whose great commitment to the application ______of new principles of immunology to the benefit of patients with skin disorders is ______recognized by this award. ______

65 Open to all meeting attendees CME Credit: .5 ASSOCIATE MEETINGS Clinical Scholars Program – Session II Saturday, May 9, 2015

International Societies for Investigative Dermatology (ISID) Informational Meeting Saturday, May 9, 2015 10:15 am – 12:15 pm Grand Ballroom, Hilton Atlanta 2:00 pm – 3:30 pm Crystal Ballroom, Hilton Atlanta Topic: “Infectious Skin Diseases”

10:15 am "Combinatorial targeting of Akt1 and SMO synergistically suppresses the growth of UV-induced BCCs in a murine model of basal cell nevus syndrome."

Arianna L. Kim, Yucui Zhu, Nathan P. Yardley, Mohammad Athar, David R. Bickers. Poster #150, Presented by Arianna L. Kim, PhD

10:30 am Q&A

10:45 am plenary Presentation Edward Cowen, MD/MHSc “New Primary Immunodeficiencies”

Edward W. Cowen, MD, MHSc is Senior Clinician and Head of the Dermatology Consultation Service in the Dermatology Branch, Center for Cancer Research, National Institutes of Health. His research interests include primary immunodeficiency, autoinflammatory skin disease, and chronic graft-versus-host disease.

11:00 am Q&A

11:15 am plenary Presentation Donald Leung, MD/PhD "Staphylococcal Infections in Atopic Dermatitis"

Dr. Leung has been the principal investigator on over 30 NIH research grants and federal contracts involving studies on immune mechanisms and treatment of atopic dermatitis over the past 25 years. He has been particularly interested in the role of S. aureus skin infections and their virulence factors in the pathobiology of atopic dermatitis. He has over 600 publications, many of them dealing with the immunology, causes and infectious complications of skin diseases, particularly atopic dermatitis. NOTES 11:30 am Q&A ______11:45 am Open Discussion ______

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66 Open to all meeting attendees CME Credit: 3 NOTES CONCURRENT MINI-SYMPOSIUM 12 ______ADAPTIVE IMMUNITY & VACCINATION ______Saturday, May 9, 2015 12:30 pm – 3:30 pm Salon D, Hilton Atlanta ______Presiders: John Harris, MD/PhD and Michael Rosenblum, MD/PhD ______1. individual naïve T cells give rise to both TRM and TCM during immune responses in vivo. Olivier Gaide, Ryan O. Emerson, Xiaodong Jiang, Rachael Clark and Thomas S. Kupper. Boston, MA and ______Seattle, WA. 12:30 pm, Poster #039 ______2. Contributions of skin resident and recirculating memory T cells to depigmentation in vitiligo. ______Jillian Richmond, Mehdi Rashighi, Priti Agarwal and John E. Harris. Worcester, MA. 12:42 pm, Poster #013 ______3. Vitiligo T cell receptor SILv44 imparts a Tc17 profile and anti-tumor reactivity on host T cells. Jonathan Eby, Jared Klarquist, Mingli Li, Derek Wainwright, Stephanie Watkins, Wiete Westerhof, ______Cheryl Paulos, Shikhar Mehrotra, Elizabeth Garrett-Mayer, Rosalie Luiten, Michael Nishimura and Caroline Le Poole. Maywood, IL; Amsterdam, Netherlands and Charleston, SC. 12:54 pm, ______Poster #047 ______4. Human skin is protected by four functionally and phenotypically discrete populations of ______resident and recirculating memory T cells. Rei Watanabe, Ahmed Gehad, Chao Yang, Laura Campbell, Jessica E. Teague, Victor Huang, Tiago R. Matos, Thomas S. Kupper and Rachael Clark. ______Boston, MA. 1:06 pm, Poster #026 ______5. Regulatory T cells facilitate cutaneous wound healing. Audrey Nosbaum, Monika Ettinger, ______Hong-An Truong, Mariela L. Pauli, Sofia V. Gearty, Abul K. Abbas and Michael D. Rosenblum. San Francisco, CA. 1:18 pm, Poster #016 ______6. GILT-mediated processing of a self and melanoma antigen in thymic epithelial cells promotes deletion and regulatory T cells. Matthew Rausch, Todd C. Metzger, Michael Waterfield, Jessica ______Cortez, Mark S. Anderson and Karen T. Hastings. Phoenix, AZ and San Francisco, CA. 1:30 pm, Poster #028 ______7. Identifying Merkel polyomavirus-specific CD4+ and CD8+ T-cells in Merkel cell carcinoma patients’ tumor-infiltrating lymphocytes. Dafina Ibrani, Jayasri G. Iyer, Natalie Vandeven, ______Natalie Miller, Olga Afanasiev, David Koelle and Paul Nghiem. Seattle, WA. 1:42 pm, Poster #015 ______8. Next generation T cell receptor sequencing reveals complex T cell dynamics in Alopecia Areata. ______Annemieke de Jong, Luzhou Xing, Ali Jabbari, Zhenpeng Dai, Vera H. Price, Madeleine Duvic, ______David Norris, Maria Hordinsky, Julian Mackay-Wiggan, Raphael Clynes and Angela Christiano. New York, NY; San Francisco, CA; Houston, TX; Denver, CO and Minneapolis, MN. 1:54 pm, ______Poster #019 ______9. Shared VH1-46 antibody gene usage in pemphigus vulgaris predicts antibody cross-reactivity ______to desmoglein 3 and rotavirus VP6. Michael Jeffrey T. Cho, Christoph Ellebrecht, Christoph M. Hammers, Gopal Sapparapu, James Crowe and Aimee Payne. Philadelphia, PA and Nashville, ______TN. 2:06 pm, Poster #018

______10. CCL17 attenuates tumor immunity by increasing regulatory T cells and Th2 cells while ______decreasing myeloid-derived suppressor cells in tumor microenvironment. Sohshi Morimura, Makoto Sugaya, Tomonori Oka, Hiraku Suga, Tomomitsu Miyagaki, Yuichiro Tsunemi, Yoshihide ______Asano, Yayoi Tada, Takafumi Kadono and Shinichi Sato. Tokyo, Japan. 2:18 pm, Poster #009

______11. Elevated thymic stromal lymphopoietin expression in the skin blocks breast carcinogenesis. ______Shadmehr Demehri, Trevor J. Cunningham, Sindhu Manivasagam, Melissa Meyer, David Denardo, Raphael Kopan and Wayne Yokoyama. St. Louis, MO and Cincinnati, OH. ______2:30 pm, Poster #021

______12. Blockade for CD155-TIGIT interaction is an effective therapy for melanoma. Takashi Inozume, ______Tomonori Yaguchi, Yutaka Kawakami and Shinji Shimada. Yamanashi, Japan and Tokyo, Japan. 2:42 pm, Poster #002

67 Open to all meeting attendees CME Credit: 3 ASSOCIATE MEETINGS CONCURRENT MINI-SYMPOSIUM 13 GROWTH FACTORS, CELL ADHESION & MATRIX BIOLOGY Saturday, May 9, 2015

International Societies for Investigative Saturday, May 9, 2015 12:30 pm – 3:30 pm Salon A/B, Hilton Atlanta Dermatology (ISID) Informational Meeting 2:00 pm – 3:30 pm Crystal Ballroom, Hilton Atlanta Presiders: C. Michael DiPersio, PhD and James K. Wahl, III, PhD

1. TGF release by fibroblasts requires regulated secretion via autophagosomes. Julian Nuechel, Katrin Blumbach, Katrin Schoenborn, Jan-Niklas Schulz, Alexandra Zuk, Gerhard Sengle, Georg Brunner, Thomas Krieg, Markus Plomann and Beate Eckes. Cologne, Germany and Muenster, Germany. 12:30 pm, Poster #484

2. EphA2 negatively regulates EGFR to promote keratinocyte differentiation. Bethany E. Perez White, Paul Thomas, Joshua Rappoport and Spiro Getsios. Chicago, IL. 12:42 pm, Poster #473

3. Exclusion of insulin and IGF-1 receptors from caveolar domains by ganglioside GM3 mediates insulin resistance. Duncan Hieu M. Dam, June J. Park, Betty Kong, Xiao-Qi Wang and Amy S. Paller. Chicago, IL. 12:54 pm, Poster #480

4. Role of integrin-linked kinase in keratinocyte survival. Lina Dagnino and Michelle Im. London, ON, Canada. 1:06 pm, Poster #496

5. RDEB fibroblast-derived periostin promotes the invasion of squamous cell carcinoma. Xinyi Wang, Yingping Hou, Jon Cogan, Olivia Lai, Weihuang Ning, David T. Woodley and Mei Chen. Los Angeles, CA. 1:18 pm, Poster #490

6. Lysyl hydroxylase 3 localizes to epidermal basement membrane and is reduced in patients with recessive dystrophic epidermolysis bullosa. Stephen Watt, Jasbani Dayal, Sheila Wright, Celine Pourreyron, James McMillan, Megan Riddle, Irwin McLean, Irene Leigh, John McGrath, Julio Salas-Alanis, Jakub Tolar and Andrew P. South. Dundee, United Kingdom; London, United Kingdom; Minneapolis, MN; Monterrey, Mexico and Philadelphia, PA. 1:30 pm, Poster #486

7. The role of the hemidesmosomal protein BP180 in granulopoiesis. Lin Lin, Bin-Jin Hwang, Ning Li, Luis A. Diaz and Zhi Liu. Chapel Hill, NC. 1:42 pm, Poster #494

8. Rapamycin modulates the glucocorticoid receptor functions, blocks atrophogene REDD1 expression, and protects skin against steroid-induced atrophy. Ekaterina Lesovaya, Elena Vinokour, Gleb Baida, Pankaj Bhalla, Kirill Kirsanov, Marianna Yakubovskaya, Leonidas Platanias, Ben Readhead, Joel Dudley and Irina Budunova. Chicago, IL; Moscow, Russian Federation and New York, NY. 1:54 pm, Poster #491

9. Oxidative stress reduces collagen production through eIF2-dependent down-regulation of NOTES transforming growth factor-beta signaling pathway in human dermal fibroblasts. Tianyuan He, Taihao Quan, John J. Voorhees and Gary J. Fisher. Ann Arbor, MI. 2:06 pm, Poster #493 ______

10. Palmitoylation of the desmosomal cadherins is important for protein stability and assembly ______dynamics. Brett J. Roberts, Robert Svoboda, Keith Johnson and James K. Wahl. Lincoln, NE. 2:18 pm, Poster #488 ______11. Desmosomal mediated mechanotransduction regulates cell adhesion and signaling. Joshua A. Broussard and Kathleen J. Green. Chicago, IL. 2:30 pm, Poster #475 ______

12. Altered desmosome organization, endocytosis and desmosome splitting in pemphigus vulgaris ______epidermis as revealed by super-resolution microscopy. Sara N. Stahley, Maxine Warren, Ron J. ______Feldman, Robert Swerlick, Alexa Mattheyses and Andrew Kowalczyk. Atlanta, GA. 2:42 pm, Poster #479 ______

68 Open to all meeting attendees CME Credit: 3 NOTES CONCURRENT MINI-SYMPOSIUM 14 ______PHOTOBIOLOGY ______Saturday, May 9, 2015 12:30 pm – 3:30 pm Salon C, Hilton Atlanta ______Presiders: Santosh Katiyar, PhD and Jeffrey Travers, MD/PhD

______1. Platelet-activating factor receptor agonists generated by radiation therapy thwart host anti-tumor immunity. Ravi Sahu, Raymond L. Konger and Jeffrey B. Travers. Indianapolis, IN. ______12:30 pm, Poster #593 ______2. The tumor suppressor p27KIP1 in keratinocytes is regulated via an autocrine mechanism ______involving the aryl hydrocarbon receptor (AHR). Marius Pollet, Jean Krutmann and Thomas Haarmann-Stemmann. Düsseldorf, Germany. 12:42 pm, Poster #589 ______3. Lipid oxidation patterns and kinetics in keratinocytes undergoing senescence-promoting stress or replicative senescence. Marie S. Narzt, Ionela M. Nagelreiter, Susanne Karner, Johannes ______Grillari, Katarzyna Figlak, Manuel Filzwieser, Valery Bochkov, Erwin Tschachler and Florian Gruber. Vienna, Austria and Steiermark, Austria. 12:54 pm, Poster #594 ______4. Alternative keratin 17 expression variation is induced by different doses of narrow-band ultraviolet B in keratinocytes via Erk1/2-dependent mechanism. Chang-xu Han, Liang Jin, ______Er-Le Dang and Gang Wang. Xi’an, China. 1:06 pm, Poster #587

______5. Circadian rhythm and skin inflammation. Amanda K. Suggs, Jacqueline Selph, Minh Lam and ______Elma D. Baron. Cleveland, OH. 1:18 pm, Poster #584 ______6. UVA and UVB induce different sets of long non-coding RNAs. Thomas M. Ruenger and Kazuyuki Yo. Providence, RI and Yokohama, Japan. 1:30 pm, Poster #595 ______7. Distinctive molecular and cellular responses to UVB in keratinoctyes and melanocytes. Masashi Nakatani, Arianna Kim and Liang Liu. New York, NY. 1:42 pm, Poster #597 ______8. UVB induces mast cell dermal recruitment and activation trough S1P production from human ______keratinocyte. Matthieu Vanderberghe, Zhenping Wang and Anna Di Nardo. La Jolla, CA. ______1:54 pm, Poster #608 ______9. Identification of glycolysis-derived -dicarbonyl metabolites as the smallest known endogenous UVA-photosensitizers in human skin cells and reconstructed epidermis. Rebecca Justiniano, ______Shuxi Qiao, Joshua D. Williams and Georg T. Wondrak. Tucson, AZ. 2:06 pm, Poster #609 ______10. Visible light-induced hyperpigmentation in human skin in vivo occurs in dark, but not in light ______skin, and is associated with differential induction of CCL18 and tyrosinase genes. Barbara Rainer, Ji Qi, Jo Martin, Aleksandra Ogurtsova, C. Conover Talbot, Sherry Leung, Luis Garza, ______Anna L. Chien and Sewon Kang. Baltimore, MD. 2:18 pm, Poster #599 ______11. Ultraviolet radiation, both UVA and UVB, influences the composition of the skin microbiome. ______Erin M. Burns, Abdullah Shaheen, Anum Muzaffar, Camli Al-Sadek, Thompson Foy, Mohammad Abdelgawwad, Sumeira Huda, Prescilia N. Isedeh, Ranjit Kumar, Travis Ptacek, Henry W. Lim, ______Iltefat H. Hamzavi, Casey D. Morrow, Craig A. Elmets and Nabiha Yusuf. Birmingham, AL and Detroit, MI. 2:30 pm, Poster #582 ______12. A meta-analysis of microRNAs expression profile in UV-radiation induced skin tumors. Ram Prasad, Tripti Singh, Mudit Vaid and Santosh K. Katiyar. Birmingham, AL. 2:42 pm, Poster #578 ______

69 Open to all meeting attendees CME Credit: 3 ASSOCIATE MEETINGS CONCURRENT MINI-SYMPOSIUM 15 Saturday, May 9, 2015 TISSUE REGENERATION & WOUND HEALING International Societies for Investigative Dermatology (ISID) Informational Meeting Saturday, May 9, 2015 12:30 pm – 3:30 pm Salon E, Hilton Atlanta 2:00 pm – 3:30 pm Crystal Ballroom, Hilton Atlanta

Presiders: Vladimir Botchkarev, MD/PhD and Marie Tuttle, MD

1. Epigenetic regulation of the wound healing: the role of Polycomb Cbx4 gene in the epithelial regeneration. Andrei Mardaryev, Ahmar Aziz, Krzysztof Poterlowicz, Tatyana Y. Sharova, Guoliang Xu, Vladimir A. Botchkarev and Andrey Sharov. Bradford, United Kingdom; Boston, MA and Shanghai, China. 12:30 pm, Poster #709

2. Reconstitution of three-dimensional skin composed of keratinocytes, fibroblasts and melanocytes induced from Muse human pluripotent stem cell. Takeshi Yamauchi, Kenshi Yamasaki, Kenichiro Tsuchiyama, Saaya Koike, Mai Inoue and Setsuya Aiba. Sendai, Japan. 12:42 pm, Poster #700

3. Cadherin endocytosis, adhesion, and cytoskeletal linkage cooperatively regulate collective cell migration. Chantel Cadwell, Benjamin A. Nanes, Daniel Conway and Andrew Kowalczyk. Atlanta, GA and Richmond, VA. 12:54 pm, Poster #704

4. IRF1 protein levels depend on microRNA miR-31 and reduced levels of IRF1 inhibit keratinocyte migration. Chase Taylor, Claudia D. Andl and Thomas Andl. Nashville, TN. 1:06 pm, Poster #711

5. Ephrin-A ligand loss enhances keratinocyte migration via ligand-independent EphA2 action. Nihal Kaplan, Bethany E. Perez White, Ji Zheng, Paul Hoover, Rosa Ventrella, William R. Swindell, Johann E. Gudjonsson, Bingcheng Wang and Spiro Getsios. Chicago, IL; Cleveland, OH and Ann Arbor, MI. 1:18 pm, Poster #723

6. Collagen XVII regulates actin dynamics and traction forces in motile keratinocytes. Sho Hiroyasu, Zachary Colburn and Jonathan Jones. Pullman, WA. 1:30 pm, Poster #703

7. Repair versus regeneration: Msx2 is required for epidermal competency during wound induced follicular neogenesis. Michael W. Hughes, Ting-Xin Jiang, Gary Lai, Christopher Schafer, Robert Maxson, Randal Widelitz and Cheng-Ming Chuong. Los Angeles, CA and Tainan, Taiwan. 1:42 pm, Poster #717

8. Paracrine regulation of wound angiogenesis through cooperation of epidermal integrins. Whitney M. Longmate, Scott P. Lyons, Sridar V. Chittur, Livingston Van De Water and C. M. DiPersio. Albany, NY and Rensselaer, NY. 1:54 pm, Poster #706 NOTES

9. Topically delivered allogeneic mesenchymal stems cells accelerate healing. Michael Lichtman, Sarah Kam, Tatyana Y. Sharova, Xiaofeng Lin, Tatyana Yufit, David Fiore, Polly Carson and Vincent ______Falanga. Boston, MA. 2:06 pm, Poster #731 ______

10. Inhibition of Apoptosis signal-regulating kinase 1 alters differentiation of the wound epithelium ______to enhance tissue regeneration. Theresa A. Freeman, Natalie Chernets, Deepa Kurpad and My G. Mahoney. Philadelphia, PA. 2:18 pm, Poster #721 ______11. CAGE sequencing reveals MAFB as an early VEGF-C induced transcription factor that mediates cutaneous lymphatic vessel differentiation and development. Lothar Dieterich, Sarah Klein, ______Anthony Mathelier, Young-Kwon Hong, Wyeth Wasserman and Michael Detmar. Zurich, Switzerland; Vancouver, BC, Canada and Los Angeles, CA. 2:30 pm, Poster #734 ______12. Estrogen receptor alpha-mediated control of growth factor production from nipple fibroblasts. Hsin-Jung Wu, Dan F. Spandau, Sunil S. Tholpady and John G. Foley. Bloomington, IN and ______Indianapolis, IN. 2:42 pm, Poster #736

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71 Abstracts PAGE titlE

70 Abstract Presentation Information

71 2015 Abstract Categories And Definitions

72-97 Poster Presentations / Abstract Titles

98-118 Author Index

119-122 Keyword Index

123-125 SID Governance Abstracts

Abstract Presentation Information

ORAL PRESENTATIONS POSTER PRESENTATIONS Oral presentations and lectures will take place at the All posters will be displayed until Saturday, May 9th at Hilton Atlanta. Minisymposium and Plenary oral 12:00 pm in the Galleria Exhibit Hall. Posters will be presentations are scheduled at the rate of five (5) per hour. viewed in three sessions as outlined below. Presenters This allows ten (10) minutes for presentation and two (2) should be at their posters for the entire discussion session. minutes for discussion. In order to coordinate sessions, Posters may not be removed early. The SID is not respon- the time limit will be strictly adhered to, and you will be sible for posters left unclaimed as of 1:00 pm on Saturday, asked to terminate your presentation by the session May 9. Unclaimed posters will not be returned. moderators. LCD projectors will be available in each lecture hall. There will be resources to display only with INSTALL ALL POSTERS IBM-compatible PowerPoint MS Office 2013 or earlier Wednesday, May 6, 2015 8:00 am – 4:00 pm versions. 35mm projectors will not be available. Computer technicians will be able to download ZIP and POSTER SESSION I CD files. All oral presentations must also be presented Odd Poster numbers 001-245 & in poster format. All presentations must be uploaded to a Even Poster numbers 246-490 common storage device at least six (6) hours prior to your Thursday May 7, 2015 10:00 am – 12:00 pm presentation. Uploads may be completed in the Speaker Ready Room (Room 201, Hilton Atlanta). POSTER SESSION II Even Poster numbers 002-244 & Odd Poster numbers 491-735 Friday, May 8, 2015 11:15 am – 1:15 pm

POSTER SESSION III Odd Poster numbers 247-489 & Even Poster numbers 492-736 Saturday, May 9, 2015 10:00 am – 12:00 pm

DISMANTLE ALL POSTERS Saturday, May 9, 2015 12:15 pm – 1:00 pm

CONFLICT OF INTEREST Due to CME Guidelines, ALL oral presentations must include a disclosure slide at the beginning of your presen- tation. If there is a real or perceived conflict of interest pertaining to your work, an announcement must be made prior to your oral presentation and also displayed on your poster.

SPEAKER READY ROOM Room 201, Hilton Atlanta will be available to all presenters during the following hours.

Wednesday, May 6, 2015 7:00 am – 8:00 pm Thursday, May 7, 2015 7:00 am – 5:00 pm Friday, May 8, 2015 7:00 am – 5:00 pm Saturday, May 9, 2015 7:00 am – 3:00 pm

72 2015 Abstract Categories And Definitions

ADAPTIVE IMMUNITY & VACCINATION GROWTH FACTORS, CELL ADHESION, & Studies of adaptive immune responses in both skin and MATRIX BIOLOGY lymphoid tissues during homeostasis, inflammation, and Studies on growth factors and the interactions of cells with infection involving T and B lymphocytes, antigen their local cellular and extracellular environment that af- presenting cells, dendritic cells, and the mechanisms and fect signaling, adhesion, migration and development. factors that control these processes. INNATE IMMUNITY, INFLAMMATION & AUTO-IMMUNITY MICROBIOLOGY Studies of clinical disease states involving autoimmunity. Studies of innate immunity, including cells, receptors and effector molecules of the innate immune response. Stud- CARCINOGENESIS & CANCER GENETICS ies of innate responses to skin microbes and infectious Studies on the development, maintenance and metastasis processes of the skin. of cancer as well as the genetic basis of skin cancer. PHOTOBIOLOGY CLINICAL RESEARCH (OBSERVATIONS, PATHOPHYSI- Studies on biological, biochemical, and molecular re- OLOGY & OUTCOMES) sponses to ultraviolet radiation in cultured cells or ani- Studies involving human subjects and not preclinical mals. animal model studies. This session will focus on pathophysiologic studies, observations of patients with PIGMENTATION & MELANOMA skin diseases, as well as outcome studies. Experimental Studies on all aspects of cutaneous or extracutaneous studies submitted to this category that do not involve hu- pigmentation; and molecular, cellular, and biological man subjects will be moved to a more appropriate facets of melanoma. Genetic studies on melanoma should category by Abstract Reviewers. be considered for the category “carcinogens and Cancer Genetics”. EPIDEMIOLOGY Studies, typically observational, involving the evaluation SKIN & HAIR DEVELOPMENTAL BIOLOGY of health or disease with respect to the skin in popula- Studies on the hair follicle, sebaceous gland, and other tions. skin appendages; developmental biology of skin and hair, including studies of the role of stem cells in normal devel- EPIDERMAL STRUCTURE & BARRIER FUNCTION opment and postnatal growth. Research on the components or regulation of keratinocyte proliferation, terminal differentiation, and/or epidermal TISSUE REGENERATION & WOUND HEALING barrier function. Wound healing and regeneration studies and studies that involve processes/signaling that affect vascular develop- GENE THERAPY & CLINICAL THERAPEUTICS ment and angiogenesis. Studies involving human subjects that include gene therapy, small or large molecules or other therapeutic ap- proaches.

GENETIC DISEASE & GENE REGULATION Studies on cutaneous gene expression and genetically- based diseases. Cancer-related genetic studies are more appropriate for “Carcinogenesis and Cancer Genetics.”

73 PosterPoster Presentations Presentations / a /bstract abstract titles titles

AdaptiveAdaptive Immunity Immunity & Vaccination& Vaccination 014 014Acne Acne vaccines vaccines targeting targeting secretory secretory CAMP CAMP factor factor of Propionibacterium of Propionibacterium All oralsAll orals[designated [designated with withan asterisk an asterisk (*)] listed (*)] listed below below are presented are presented in the in the acnes.acnes. Chun-Ming Chun-Ming Huang Huang. San .Diego, San Diego, CA. CA. AdaptiveAdaptive Immunity Immunity & Vaccination & Vaccination Minisymposium Minisymposium on Saturday, on Saturday, May 9, May 2015, 9, 2015, 015*015* Identifying Identifying Merkel Merkel polyomavirus-specific polyomavirus-specific CD4+ CD4+and CD8+and T-cellsCD8+ T-cells in in fromfrom 12:30-3:30 12:30-3:30 pm in pm Salon in Salon D, Hilton D, Hilton Atlanta. Atlanta. Orals Orals designated designated by two by asteriskstwo asterisks MerkelMerkel cell carcinoma cell carcinoma patients’ patients’ tumor-infiltrating tumor-infiltrating lymphocytes. lymphocytes. Dafina Dafina (**) will(**) be will presented be presented during during a Plenary a Plenary Session. Session. Orals Orals designated designated by three by three IbraniIbrani, Jayasri, Jayasri G Iyer, G NatalieIyer, Natalie Vandeven, Vandeven, Natalie Natalie Miller, Miller, Olga OlgaAfanasiev, Afanasiev, asterisksasterisks (***) (***) will be will presented be presented during during the Interdisciplinary the Interdisciplinary Spotlight: Spotlight: Skin Skin DavidDavid Koelle Koelle and Pauland Nghiem.Paul Nghiem. Seattle, Seattle, WA. WA. CancerCancer Minisymposium Minisymposium on Friday, on Friday, May May8, 2015, 8, 2015, from from 2:00 2:00– 5:00 – 5:00pm in pm the in Grand the Grand 016* 016* Regulatory Regulatory T cells T cellsfacilitate facilitate cutaneous cutaneous wound wound healing. healing. Audrey Audrey Nosbaum Nosbaum, , Ballroom,Ballroom, Hilton Hilton Atlanta. Atlanta. MonikaMonika Ettinger, Ettinger, Hong-An Hong-An Truong, Truong, Mariela Mariela L Pauli, L Pauli,Sofia SofiaV. Gearty, V. Gearty, Abul K. Abul K. AbbasAbbas and Michaeland Michael David David Rosenblum. Rosenblum. San Francisco, San Francisco, CA. CA. + + + + 001 001RON2315: RON2315: A novel A novel human human biologic biologic for the for topical the topical treatment treatment of psoriasis. of psoriasis. 017 017Quantification Quantification of CD69 ofCD103 CD69 CD103 skin TskinRM cells TRM cellsin chronic in chronic atopic atopic dermatitis. dermatitis. ThomasThomas Gadek Gadek. Portola. Portola Valley, Valley, CA. CA. SeoHyeongSeoHyeong KIM, KIMChang, Chang Ook Park,Ook Park, Jung JungU Shin, U Shin, Ji Yeon Ji YeonNoh, Noh,Shan Shan Jin, Jin, 002*002* Blockade Blockade for CD155-TIGIT for CD155-TIGIT interaction interaction is an iseffective an effective therapy therapy for for HeminHemin Lee, JungsooLee, Jungsoo Lee, ThomasLee, Thomas S. Kupper S. Kupper and Kwangand Kwang Hoon Hoon Lee. Seoul,Lee. Seoul, melanoma.melanoma. Takashi Takashi Inozume Inozume, Tomonori, Tomonori Yaguchi, Yaguchi, Yutaka Yutaka Kawakami Kawakami and and KoreaKorea (the Republic(the Republic of) and of) Boston,and Boston, MA. MA. ShinjiShinji Shimada. Shimada. Chuo, Chuo, Japan Japan and Shinjyuku,and Shinjyuku, Japan. Japan. 018*018* Shared Shared VH1-46 VH1-46 antibody antibody gene geneusage usage in pemphigus in pemphigus vulgaris vulgaris predicts predicts 003 003Migratory Migratory DC temper DC temper subcutaneous subcutaneous immunity immunity through through key tolerance key tolerance antibodyantibody cross-reactivity cross-reactivity to desmoglein to desmoglein 3 and 3 rotavirusand rotavirus VP6. Michael VP6. Michael pathways.pathways. Niroshana Niroshana Anandasabapathy Anandasabapathy, Christopher, Christopher Nirschl, Nirschl, Yong YongLiu, Liu, JeffreyJeffrey Tejada Tejada Cho, ChristophCho, Christoph Ellebrecht, Ellebrecht, Christoph Christoph Matthias Matthias Hammers, Hammers, ShamimShamim Mollah, Mollah, Rachel Rachel E. Feder, E. Feder, Pinru Pinru Wu, PeterWu, Peter Sage Sageand Arleneand Arlene H H GopalGopal Sapparapu, Sapparapu, James James Crowe Crowe and Aimeeand Aimee S Payne. S Payne. Philadelphia, Philadelphia, PA and PA and Sharpe.Sharpe. Boston, Boston, MA and MA Newand NewYork, York, NY. NY. Nashville,Nashville, TN. TN. 004 004Rationale Rationale and designand design of a novelof a novel dendritic dendritic cell targetedcell targeted vaccine vaccine for basalfor basal019* 019* Next Nextgeneration generation T cell T receptorcell receptor sequencing sequencing reveals reveals complex complex T cell T cell cell carcinoma.cell carcinoma. Karyn Karyn Haitz Haitz, Steven, Steven R Barthel, R Barthel, Yong YongLiu, Christopher Liu, Christopher dynamicsdynamics in Alopecia in Alopecia Areata Areata . Annemieke . Annemieke de Jong de ,Jong Luzhou, Luzhou Xing, Xing, Ali Ali Nirschl,Nirschl, Ervin Ervin Epstein Epstein and Niroshanaand Niroshana Anandasabapathy. Anandasabapathy. Boston, Boston, MA and MA and Jabbari,Jabbari, Zhenpeng Zhenpeng Dai, VeraDai, VeraH Price, H Price, Madeleine Madeleine Duvic, Duvic, David David Norris, Norris, Oakland,Oakland, CA. CA. MariaMaria Hordinsky, Hordinsky, Julian Julian Mackay-Wiggan, Mackay-Wiggan, Raphael Raphael Clynes Clynes and Angelaand Angela 005 005An exAn vivo ex skinvivo modelskin model that combinesthat combines topical topical skin penetrationskin penetration and Th17and Th17 Christiano.Christiano. New York,New York,NY; SanNY; Francisco,San Francisco, CA; Houston,CA; Houston, TX; Denver,TX; Denver, CO and CO and stimulation.stimulation. Mary Mary Bedard Bedard, Steven, Steven Cook, Cook, Leandro Leandro Santos, Santos, Jessica Jessica Neil, Neil, Minneapolis,Minneapolis, MN. MN. CarlosCarlos Eduardo Eduardo Peredo, Peredo, Susan Susan H Smith, H Smith, Javier Javier Cote-Sierra Cote-Sierra and Jonand Lenn. Jon Lenn. 020 020Calcitonin Calcitonin gene-related gene-related peptide peptide (CGRP) (CGRP) induces induces endothelial endothelial cells (EC)cells to(EC) to ResearchResearch Triangle Triangle Park, Park, NC. NC. bias Langerhansbias Langerhans cell (LC) cell antigen(LC) antigen presentation presentation towards towards a Th17 a Th17response response throughthrough induction induction of soluble of soluble mediators. mediators. Wanhong Wanhong Ding ,Ding Lori, LLori Stohl, L Stohl, 006 006Immunomodulatory Immunomodulatory effects effects of AM1030, of AM1030, a topical a topical 5-HT2B 5-HT receptor2B receptor antagonistantagonist in development in development for atopic for atopic dermatitis. dermatitis. Niklas Niklas Palmqvist Palmqvist, Max, Max John JohnA Wagner, A Wagner, Linghui Linghui Xu and Xu Richardand Richard David David Granstein. Granstein. New NewYork, York, NY. NY. Siller,Siller, Anders Anders Sjödin, Sjödin, Helena Helena Arozenius, Arozenius, Christina Christina Wenglén, Wenglén, Anna-Carin Anna-Carin 021*021* Elevated Elevated thymic thymic stromal stromal lymphopoietin lymphopoietin expression expression in the in skinthe skinblocks blocks Ryde,Ryde, Lars Pettersson,Lars Pettersson, Cecilia Cecilia Klint, Klint,Anna AnnaPramhed, Pramhed, Anna AnnaLöfdahl Löfdahl and and breastbreast carcinogenesis. carcinogenesis. Shadmehr Shadmehr Demehri Demehri, Trevor, Trevor J Cunningham, J Cunningham, Sindhu Sindhu GunillaGunilla Ekström. Ekström. Lund, Lund, Sweden. Sweden. Manivasagam,Manivasagam, Melissa Melissa Meyer, Meyer, David David Denardo, Denardo, Raphael Raphael Kopan Kopan and Wayneand Wayne 007 007Phenotypic Phenotypic analysis analysis of dendritic of dendritic cells infiltratingcells infiltrating a spontaneous a spontaneous model model Yokoyama.Yokoyama. St. Louis, St. Louis, MO andMO Cincinnati,and Cincinnati, OH. OH. of basalof basal cell carcinoma. cell carcinoma. Christopher Christopher Nirschl Nirschl, Yong, YongLiu, Pinru Liu, Pinru Wu, KarynWu, Karyn 022 022Topical Topical application application of eupatilin of eupatilin ameliorates ameliorates atopic atopic dermatitis-like dermatitis-like skin skin HaitzHaitz and Niroshanaand Niroshana Anandasabapathy. Anandasabapathy. Boston, Boston, MA. MA. lesionslesions of NC/Nga of NC/Nga mice. mice. Young Young Min ParkMin ,Park Ji Hyun, Ji Hyun Lee, YeLee, Jin Ye Lee Jin and Lee Junand Jun 008 008Potential Potential mechanisms mechanisms for loss for lossof hair of folliclehair follicle immune immune privilege privilege in in youngyoung Lee. Seoul,Lee. Seoul, Korea Korea (the Republic(the Republic of). of). + + patientspatients with alopeciawith alopecia areata areata following following hepatitis hepatitis B vaccination. B vaccination. 023 023CD8 ααCD8 Tαα cells T cellscontribute contribute to lichen to lichen planus planus independence independence of LAMP1- of LAMP1- ChristopherChristopher Richardson Richardson, Elaine, Elaine Gilmore Gilmore and Brianand Brian Poligone. Poligone. Rochester, Rochester, NY. NY. meditatedmeditated degranulation. degranulation. Bing BingLi, Xiuwen Li, Xiuwen Sun and Sun Gangand Gang Wang. Wang. Xi’an, Xi’an, 009*009* CCL17 CCL17 attenuates attenuates tumor tumor immunity immunity by increasing by increasing regulatory regulatory T cells T cellsand and China.China. Th2 cellsTh2 cellswhile while decreasing decreasing myeloid-derived myeloid-derived suppressor suppressor cells cellsin tumor in tumor 024 024Immunomodulatory Immunomodulatory effects effects of nanoparticles of nanoparticles on the on contactthe contact microenvironment.microenvironment. Makoto Makoto Sugaya Sugaya, Sohshi, Sohshi Morimura, Morimura, Tomonori Tomonori Oka, Oka, hypersensitivityhypersensitivity response response in C57BL/6 in C57BL/6 hairless hairless mice. Samreenmice. Samreen Jatana Jatana, , HirakuHiraku Suga, Suga, Tomomitsu Tomomitsu Miyagaki, Miyagaki, Yuichiro Yuichiro Tsunemi, Tsunemi, Yoshihide Yoshihide Asano, Asano, BrianBrian C Palmer C Palmer and Lisaand A Lisa DeLouise. A DeLouise. Rochester, Rochester, NY. NY. YayoiYayoi Tada, Tada, Takafumi Takafumi Kadono Kadono and Shinichiand Shinichi Sato. Sato. Tokyo, Tokyo, Japan. Japan. 025 025Capturing Capturing functional functional conservation conservation between between human human skin skinand andmouse mouse DC DC 010 010Distinctive Distinctive downmodulation downmodulation of plasmacytoid of plasmacytoid dendritic dendritic cell bycell vitamin by vitamin systemssystems for generating for generating better better vaccines. vaccines. Eynav Eynav Klechevsky Klechevsky. Saint. Saint Louis, Louis, D3 analogueD3 analogue in its in interferon- its interferon-α productionα production and chemotacticand chemotactic activity. activity. MO. MO. TakahiroTakahiro Suzuki Suzuki, Yoshiki, Yoshiki Tokura. Tokura. Hamamatsu, Hamamatsu, Japan. Japan. 026*026* Human Human skin isskin protected is protected by four by functionallyfour functionally and phenotypicallyand phenotypically 011**011** A wave A wave of regulatory of regulatory T cells T cellsinto neonatalinto neonatal skin mediatesskin mediates tolerance tolerance to to discretediscrete populations populations of resident of resident and recirculatingand recirculating memory memory T cells. T Rei cells. Rei commensalcommensal microbes microbes . Tiffany . Tiffany C Scharschmidt C Scharschmidt, Kimberly, Kimberly S Vasquez, S Vasquez, Hong- Hong- WatanabeWatanabe, Ahmed, Ahmed Gehad, Gehad, Chao Chao Yang, Yang, Laura Laura Campbell, Campbell, Jessica Jessica Emberley Emberley An Truong,An Truong, Sofia Sofia V. Gearty, V. Gearty, Mariela Mariela L Pauli, L Pauli,Audrey Audrey Nosbaum, Nosbaum, Michael Michael Teague,Teague, Victor Victor Huang, Huang, Tiago Tiago R Matos, R Matos, Thomas Thomas S. Kupper S. Kupper and Rachaeland Rachael Otto,Otto, James James J Moon, J Moon, Abul AbulK. Abbas, K. Abbas, Michael Michael A Fischbach A Fischbach and andMichael Michael Clark.Clark. Boston, Boston, MA. MA. DavidDavid Rosenblum. Rosenblum. San Francisco, San Francisco, CA; Bethesda, CA; Bethesda, MD and MD Charlestown,and Charlestown, 027 027Novel Novel STAT3 STAT3 inhibitor inhibitor LLL12 LLL12 significantly significantly reduces reduces IL-17, IL-17, IL-22, IL-22, and IFN-and IFN- MA. MA. gammagamma mRNA mRNA expression expression in psoriatic in psoriatic PBMCs. PBMCs. Justin Justin G Hastings G Hastings, Xiaoli, Xiaoli 012 012Keratin Keratin 17 enhances 17 enhances the chemotaxisthe chemotaxis of neutrophils of neutrophils through through regulating regulating Zhang,Zhang, Jiayuh Jiayuh Lin, Chenglong Lin, Chenglong Li and Li Henryand Henry K Wong. K Wong. Columbus, Columbus, OH. OH. chemokinechemokine CXCL1 CXCL1 secretion secretion in keratinocytes in keratinocytes via PI3k/AKT/NF- via PI3k/AKT/NF-κB κB 028*028* GILT-mediated GILT-mediated processing processing of a selfof a and self melanomaand melanoma antigen antigen in thymic in thymic pathway.pathway. Er-Le Er-Le Dang Dang, Liang, Liang Jin, Chang-xu Jin, Chang-xu Han, Han,Bing BingLi, Man Li, ManJiang Jiang and and epithelialepithelial cells cellspromotes promotes deletion deletion and regulatoryand regulatory T cells. T Karencells. Karen Taraszka Taraszka GangGang Wang. Wang. Xi’an, Xi’an, China. China. HastingsHastings, Matthew, Matthew Rausch, Rausch, Todd ToddC. Metzger, C. Metzger, Michael Michael Waterfield, Waterfield, Jessica Jessica 013*013* Contributions Contributions of skin of residentskin resident and recirculatingand recirculating memory memory T cells T cellsto to CortezCortez and Markand Mark S. Anderson. S. Anderson. Phoenix, Phoenix, AZ and AZ Sanand Francisco, San Francisco, CA. CA. depigmentationdepigmentation in vitiligo. in vitiligo. Jillian Jillian Richmond Richmond, Mehdi, Mehdi Rashighi, Rashighi, Priti Priti AgarwalAgarwal and Johnand JohnE Harris. E Harris. Worcester, Worcester, MA. MA. Notes:Notes:

1 1 74 PPosteroster P Presentationsresentations // aabstractbstract ttitlesitles

Adaptive Immunity & Vaccination 029014 DissectingAcne vaccines the targetingrole of the secretory CD27-CD70 CAMP pathway factor in of TregPropionibacterium function in the 045 Topical application of an epidermal growth factor receptor kinase All orals [designated with an asterisk (*)] listed below are presented in the skin.acnes. Kelly Chun-Ming A. Remedios Huang, Hong-An. San Diego, Truong, CA. Sofia V. Gearty, Mariela L Pauli, inhibitor enhances the response to influenza vaccination. Brian Paul Adaptive Immunity & Vaccination Minisymposium on Saturday, May 9, 2015, 015* AbulIdentifying K. Abbas Merkeland Michael polyomavirus-specific David Rosenblum. CD4+San Francisco,and CD8+ T-cellsCA. in Pollack, Ioanna Skountzou, Joanna A. Pulit-Penaloza, Richard W. Compans, from 12:30-3:30 pm in Salon D, Hilton Atlanta. Orals designated by two asterisks 030 AutocrineMerkel cell neurokinin-1 carcinoma patients’ receptor agoniststumor-infiltrating induce T cell lymphocytes. survival and Dafina Bishu Sapkota and E. Stein Esser. Decatur, GA and Atlanta, GA. (**) will be presented during a Plenary Session. Orals designated by three promoteIbrani, Jayasri potent G Iyer,cutaneous Natalie immunity. Vandeven, Adriana Natalie TMiller, Larregina Olga, Afanasiev,Darling Rojas- 046 Responses to influenza vaccine after rituximab therapy in patients asterisks (***) will be presented during the Interdisciplinary Spotlight: Skin Canales,David Koelle Tina andL. Sumpter, Paul Nghiem. William Seattle, Shufesky, WA. Olga Tkacheva and Adrian with autoimmune blistering diseases. Alice Cho, Bridget Bradley, Lalita Cancer Minisymposium on Friday, May 8, 2015, from 2:00 – 5:00 pm in the Grand 016* Morelli.Regulatory Pittsburgh, T cells facilitate PA. cutaneous wound healing. Audrey Nosbaum, Priyamvada, Yevgeniy Kovalenkov, Ron J Feldman and Jens Wrammert. Ballroom, Hilton Atlanta. 031 CalciumMonika Ettinger,signaling for Hong-An monitoring Truong, antigen-specific Mariela L Pauli, TSofia cell V.stimulation. Gearty, Abul K. Atlanta, GA. NourAbbas Kibbi and, MichaelEnping Hong, David DouglasRosenblum. Hanlon, San RichardFrancisco, Edelson, CA. Tarek Fahmy 047* Vitiligo T cell receptor SILv44 imparts a Tc17 profile and anti-tumor + + 001 RON2315: A novel human biologic for the topical treatment of psoriasis. 017 andQuantification Robert E Tigelaar. of NewCD69 CD103 Haven, skin CT. TRM cells in chronic atopic dermatitis. reactivity on host T cells. Caroline Le Poole, Jonathan Eby, Jared Klarquist, Thomas Gadek. Portola Valley, CA. 032 CutaneousSeoHyeong genetic KIM, Chang vaccination Ook Park, targeting Jung U Shin, dermal Ji Yeon DC Noh, subsets Shan for Jin, Mingli Li, Derek Wainwright, Stephanie Watkins, Wiete Westerhof, 002* Blockade for CD155-TIGIT interaction is an effective therapy for enhancedHemin Lee, antitumor Jungsoo Lee, immunity. Thomas Zhaoyang S. Kupper You and, Yi Kwang Zhang Hoon and LouisLee. Seoul,D. Falo. Cheryl Paulos, Shikhar Mehrotra, Elizabeth Garrett-Mayer, Rosalie Luiten melanoma. Takashi Inozume, Tomonori Yaguchi, Yutaka Kawakami and Pittsburgh,Korea (the Republic PA. of) and Boston, MA. and Michael Nishimura. Maywood, IL; Amsterdam, Netherlands and Shinji Shimada. Chuo, Japan and Shinjyuku, Japan. 033018* CCR2Shared presence VH1-46 isantibody nonessential gene forusage acute in pemphigusand chronic vulgaris psoriasisform predicts skin Charleston, SC. 003 Migratory DC temper subcutaneous immunity through key tolerance inflammationantibody cross-reactivity . Yumeng Li, Yito Fritz, desmoglein Jackelyn 3 B andGolden, rotavirus Doina VP6. Diaconu, Michael 048 Tissue basophilia in Stat6VT mice, a T cell-dependent model of atopic pathways. Niroshana Anandasabapathy, Christopher Nirschl, Yong Liu, MayaJeffrey Camhi, Tejada Thomas Cho, Christoph McCormick Ellebrecht, and Nicole Christoph L Ward. Matthias Cleveland, Hammers, OH. dermatitis. Anita Thyagarajan-Sahu, Leroy J Seymour, Valerie N Nemeth, Shamim Mollah, Rachel E. Feder, Pinru Wu, Peter Sage and Arlene H 034 RegulatoryGopal Sapparapu, T-cells suppressJames Crowe innate and lymphoid Aimee S Payne.cells in Philadelphia, skin. Anubhav PA and Mark H Kaplan and Matthew J Turner. Indianapolis, IN. Sharpe. Boston, MA and New York, NY. NarainNashville, Mathur TN. , Hong-An Truong, Abul K. Abbas and Michael David 004 Rationale and design of a novel dendritic cell targeted vaccine for basal 019* Rosenblum.Next generation San Francisco, T cell receptor CA. sequencing reveals complex T cell cell carcinoma. Karyn Haitz, Steven R Barthel, Yong Liu, Christopher 035 Inductiondynamics inof Alopeciaskin resident Areata and . Annemieke systemic T-cell de Jong immunity, Luzhou by Xing, cutaneous Ali Nirschl, Ervin Epstein and Niroshana Anandasabapathy. Boston, MA and immunizationJabbari, Zhenpeng using Dai, dissolvable Vera H Price, microneedle Madeleine arrays. Duvic, Blake David Elizabeth Norris, Auto-Immunity Oakland, CA. FriedmanMaria Hordinsky,, Cara Carey Julian and Mackay-Wiggan, Louis D. Falo. Pittsburgh, Raphael Clynes PA. and Angela All orals [designated with an asterisk (*)] listed below are presented in the Auto- 005 An ex vivo skin model that combines topical skin penetration and Th17 036 PediatricChristiano. atopic New dermatitis York, NY; San is Francisco,characterized CA; Houston,by increased TX; T-cellDenver, activation CO and immunity Minisymposium on Thursday, May 7, 2015, from 2:00-5:00 pm in Salon stimulation. Mary Bedard, Steven Cook, Leandro Santos, Jessica Neil, withMinneapolis, aberrant MN. T-cell development. Tali Czarnowicki, Hitokazu Esaki, Juana E, Hilton Atlanta. Orals designated by two asterisks (**) will be presented during Carlos Eduardo Peredo, Susan H Smith, Javier Cote-Sierra and Jon Lenn. 020 Gonzalez,Calcitonin Dana gene-related Malajian, peptide Sreya Talasila, (CGRP) Adam induces Berry, endothelial Jayla Gray, cells Shinji (EC) to a Plenary Session. Orals designated by three asterisks (***) will be presented Research Triangle Park, NC. Noda,bias Langerhans James G Krueger, cell (LC) Emma antigen Guttman-Yassky presentation andtowards Amy S.a Paller.Th17 response New during the Interdisciplinary Spotlight: Skin Cancer Minisymposium on Friday, May York,through NY andinduction Chicago, of IL.soluble mediators. Wanhong Ding, Lori L Stohl, 8, 2015, from 2:00 – 5:00 pm in the Grand Ballroom, Hilton Atlanta. 006 Immunomodulatory effects of AM1030, a topical 5-HT2B receptor antagonist in development for atopic dermatitis. Niklas Palmqvist, Max 037 Skin-mediatedJohn A Wagner, promotion Linghui Xu andof thrombosis Richard David is abrogated Granstein. following New York, IL-23/ NY. Siller, Anders Sjödin, Helena Arozenius, Christina Wenglén, Anna-Carin 021* IL-17Elevated inhibition thymic stromalor IL-6 deletion lymphopoietin in mouse expression models of in psoriasis.the skin Nicole blocks 049 The tryptophan metabolism enzyme, L-kynureninase, is a novel Ryde, Lars Pettersson, Cecilia Klint, Anna Pramhed, Anna Löfdahl and Lbreast Ward ,carcinogenesis. Jackelyn B Golden, Shadmehr Yi Fritz, Demehri Yumeng, Li,Trevor Yunmei J Cunningham, Wang, Daniel Sindhu I inflammatory factor in psoriasis and other inflammatory diseases. Jamie Gunilla Ekström. Lund, Sweden. SimonManivasagam, and Thomas Melissa McCormick. Meyer, David Cleveland, Denardo, OH. Raphael Kopan and Wayne Lynn Harden, Steven M Lewis, Samantha Lish, Mayte Suarez-Farinas, 007 Phenotypic analysis of dendritic cells infiltrating a spontaneous model 038 EffectYokoyama. of enteric St. Louis, viral MO infection and Cincinnati, on graft-versus-host OH. disease severity. Kyle Daniel Gareau, Tim Lentini, Leanne Johnson-Huang, James G Krueger and of basal cell carcinoma. Christopher Nirschl, Yong Liu, Pinru Wu, Karyn 022 EashTopical, Matthew application Cooper, of eupatilinTimothy Niceameliorates and John atopic F DiPersio. dermatitis-like Saint Louis, skin Michelle Lowes. New York, NY and Bronx, NY. Haitz and Niroshana Anandasabapathy. Boston, MA. MO.lesions of NC/Nga mice. Young Min Park, Ji Hyun Lee, Ye Jin Lee and Jun 050 Predictors of skin disease outcome in rituximab-treated refractory young Lee. Seoul, Korea (the Republic of). 008 Potential mechanisms for loss of hair follicle immune privilege in 039* Individual naïve T cells give rise to both TRM and TCM during immune dermatomyositis patients. Jeannette M. Olazagasti, Cynthia S. Crowson, + patients with alopecia areata following hepatitis B vaccination. 023 responsesCD8αα T cellsin vivo. contribute Olivier Gaide to lichen, Ryan planus O Emerson, independence Xiaodong of Jiang, LAMP1- Molly S. Hein, Consuelo Lopez de Padilla, Rohit Aggarwal, Chester V. Oddis Christopher Richardson, Elaine Gilmore and Brian Poligone. Rochester, NY. Rachaelmeditated Clark degranulation. and Thomas S.Bing Kupper. Li, Xiuwen Boston, Sun MA and and Gang Seattle, Wang. Xi’an,WA. and Ann M. Reed. Rochester, MN; Pittsburgh, PA and Durham, NC. 009* CCL17 attenuates tumor immunity by increasing regulatory T cells and 040 ENTPD1China. and PD-1/PD-1 ligands are highly expressed by skin-resident 051 TNF-α antagonist induced cutaneous lupus. Emily C Milam, Sarika Th2 cells while decreasing myeloid-derived suppressor cells in tumor 024 immuneImmunomodulatory cells in subsets effects of human of nanoparticles SCC . Amanda on S theMacLeod contact, Christina Ramachandran and Andrew G Franks. New York, NY. microenvironment. Makoto Sugaya, Sohshi Morimura, Tomonori Oka, McCray,hypersensitivity Jonathan responseCook, Robert in C57BL/6 Streilein, hairless Simone mice.Degan, Samreen Wendy Jatana Havran, 052 Dermal vascular changes in the C3H/HeJ alopecia areata mouse model. Hiraku Suga, Tomomitsu Miyagaki, Yuichiro Tsunemi, Yoshihide Asano, andBrian Jennifer C Palmer Y Zhang. and Lisa Durham, A DeLouise. NC. Rochester, NY. Lloyd E. King, Kathleen A Silva, Victoria E Kennedy, Timothy M Stearns and Yayoi Tada, Takafumi Kadono and Shinichi Sato. Tokyo, Japan. 041025 TwoCapturing populations functional of skin conservation CD4 memory between T cells withhuman distinct skin and migratory mouse DC John Paul Sundberg. Nashville, TN and Bar Harbor, ME. 010 Distinctive downmodulation of plasmacytoid dendritic cell by vitamin propertiessystems for aftergenerating C. albicans better infection. vaccines. Chang Eynav Ook Klechevsky Park, Rachael. Saint Clark, Louis, 053 Langerhans cells promote the development of imiquimod-induced D3 analogue in its interferon-α production and chemotactic activity. RobertMO. C. Fuhlbrigge, Xiaodong Jiang, Tian Tian, Charles Lin, Xiujun Fu, Rei psoriasis-like dermatitis by producing IL-23. Shuhong Sun, Chunying Xiao Takahiro Suzuki, Yoshiki Tokura. Hamamatsu, Japan. 026* WatanabeHuman skin and is Thomasprotected S. byKupper. four functionally Boston, MA. and phenotypically and Wei Li. Xi’An, China. 011** A wave of regulatory T cells into neonatal skin mediates tolerance to 042 Dustdiscrete mite populations is a strong activator of resident of IL-17and recirculating pathway genes memory and is T distinctcells. Rei 054* Essential requirement for IRF7 in the production of autoantibodies in commensal microbes . Tiffany C Scharschmidt, Kimberly S Vasquez, Hong- fromWatanabe the atopic, Ahmed dermatitis Gehad, Chao skin Yang, phenotype. Laura SandraCampbell, Garcet Jessica, Benjamin Emberley murine lupus. Fumi Miyagawa, Hideo Asada. Kashihara, Japan. An Truong, Sofia V. Gearty, Mariela L Pauli, Audrey Nosbaum, Michael Ungar,Teague, Avner Victor Shemer, Huang, James Tiago RG Matos,Krueger Thomas and Emma S. Kupper Guttman-Yassky. and Rachael New 055* Skin-homing and systemic T-cell subsets show higher activation in atopic Otto, James J Moon, Abul K. Abbas, Michael A Fischbach and Michael York,Clark. NY Boston, and Tel-Aviv, MA. Israel. dermatitis versus psoriasis. Juana Gonzalez, Tali Czarnowicki, Avner David Rosenblum. San Francisco, CA; Bethesda, MD and Charlestown, 043027 GlobalNovel STAT3screening inhibitor for skin LLL12 homing significantly program reduces genes in IL-17, CD8 +IL-22, T cells and after IFN- Shemer, Mayte Suarez-Farinas, James G Krueger and Emma Guttman- MA. livegamma viral mRNA immunization. expression Youdong in psoriatic Pan, Tian PBMCs. Tian, Justin Chang G OokHastings Park,, Xiaoli Serena Yassky. New York, NY and Tel Aviv, Israel. 012 Keratin 17 enhances the chemotaxis of neutrophils through regulating Lofftus,Zhang, Jiayuh Sherrie Lin, J. Chenglong Divito, Robert Li and C. HenryFuhlbrigge K Wong. and Columbus,Thomas S. OH.Kupper. 056 Ajulemic acid, a novel cannabinoid, suppresses the secretion of tumor chemokine CXCL1 secretion in keratinocytes via PI3k/AKT/NF-κB 028* Boston,GILT-mediated MA. processing of a self and melanoma antigen in thymic necrosis factor alpha and interferon alpha from the peripheral blood pathway. Er-Le Dang, Liang Jin, Chang-xu Han, Bing Li, Man Jiang and 044 Theepithelial proteasome cells promotes inhibitor deletion Bortezomib and inhibits regulatory the functionT cells. Karen of Taraszkaperipheral mononuclear cells of dermatomyositis patients in vitro. Elizabeth S Gang Wang. Xi’an, China. dendriticHastings, Matthewcells and inducesRausch, apoptosis.Todd C. Metzger, Zhongbin Michael Lai, Thomas Waterfield, M. Ruenger. Jessica Robinson, Muhammad Bashir, Paul Alves, Neelam Khan, Janice Tiao, 013* Contributions of skin resident and recirculating memory T cells to Providence,Cortez and Mark RI. S. Anderson. Phoenix, AZ and San Francisco, CA. Lauren Goldlust Okon, Joyce Okawa, Rui Feng and Victoria Werth. depigmentation in vitiligo. Jillian Richmond, Mehdi Rashighi, Priti Philadelphia, PA and New York, NY. Agarwal and John E Harris. Worcester, MA.

Notes: Notes:

75 1 2 PPosteroster P Presentationsresentations / /a abstractbstract t titlesitles

Adaptive057 Peripheral Immunity blood gene expression& Vaccination identifies systemic pathways and 014073 AcneUnmet vaccines need targetingfor mental secretory health care CAMP in cutaneous factor of Propionibacteriumlupus erythematosus All orals [designatedprocesses in with chronic an asterisk cutaneous (*)] listedlupus below erythematosus are presented (CCLE) in .the Animesh A. acnes.and dermatomyositis. Chun-Ming Huang Jordan. San Diego, C Achtman CA. , Joyce Okawa and Victoria AdaptiveSinha Immunity, Rama & Dey-Rao.Vaccination Buffalo, Minisymposium NY. on Saturday, May 9, 2015, 015* IdentifyingWerth. Philadelphia, Merkel polyomavirus-specific PA. CD4+ and CD8+ T-cells in from058 12:30-3:30Serum levelspm in ofSalon soluble D, Hilton PD-1 Atlanta. and PD-L2 Orals correlate designated with by disease two asterisks severity 074 MerkelEpigenetic cell carcinoma studies of patients’ oral lichen tumor-infiltrating planus as a model lymphocytes.for inflammation- Dafina (**) will bein presentedsystemic sclerosis. during a AyumiPlenary Yoshizaki Session., OralsShinichi designated Sato. Tokyo, by three Japan. Ibranimediated, Jayasri cancer G Iyer, development Natalie Vandeven, via malignant Natalie Miller, reprogramming. Olga Afanasiev, Nasim asterisks059** (***)Desmoglein will be presented3 chimeric duringautoantibody the Interdisciplinary receptor T cells: Spotlight: A novel Skin strategy DavidFazel Koelle, Clifford and PaulG. Tepper, Nghiem. Yoshihiro Seattle, Izumiya, WA. William Murphy and Parastoo Cancer Minisymposiumfor immunotherapy on Friday, of pemphigus May 8, 2015, vulgaris. from 2:00Christoph – 5:00 Ellebrecht pm in the, MichaelGrand 016* RegulatoryDavari. Sacramento, T cells facilitate CA. cutaneous wound healing. Audrey Nosbaum, Ballroom,Jeffrey Hilton Atlanta.Tejada Cho, Xuming Mao, Vijay G Bhoj, Ching-Yi Tsai, Selene 075 MonikaOxidative Ettinger, stress-induced Hong-An Truong,calreticulin/gC1qR Mariela L Pauli, complex Sofia V.production Gearty, Abul may K. Nunez-Cruz, Michael C Milone and Aimee Sue Payne. Philadelphia, PA. Abbasprevent and cells Michael from David apoptosis: Rosenblum. a new San insight Francisco, into the CA. destruction of + + 001060 RON2315:Comparison A novel of anti-desmoglein human biologic forB cell the repertoire topical treatment and anti-desmoglein of psoriasis. 017 Quantificationmelanocytes. Ling of LiuCD69 ,CD103 Pu Song, skin Yajun TRM Zhang,cells in Chunyingchronic atopic Li and dermatitis. Tianwen Thomasantibody Gadek repertoire. Portola in Valley, pemphigus CA. patients. Jing Chen, Qi Zheng, SeoHyeongGao. Xi’an, KIM China., Chang Ook Park, Jung U Shin, Ji Yeon Noh, Shan Jin, 002* BlockadeChristoph for Ellebrecht, CD155-TIGIT Christoph interaction Matthias is an Hammers,effective Hsintherapy Yao Tang,for 076 HeminPlumbagin Lee, Jungsoo was a potential Lee, Thomas therapeutic S. Kupper and medicine Kwang for Hoon psoriasis Lee. Seoul, by melanoma.Chenyan Lin, Takashi Lars Komorowski Inozume, Tomonori and John Yaguchi, R Stanley. Yutaka Philadelphia, Kawakami PA; and Koreainhibiting (the Republic the proliferation of) and Boston, and MA.secretion of inflammation cytokines of ShinjiLübeck, Shimada. Germany Chuo, and Japan Luebeck, and Shinjyuku,Germany. Japan. 018* Sharedkeratinocyte VH1-46 antibody . Yuan Zhang gene, Gang usage Wang. in pemphigus Xi’an, China. vulgaris predicts 003061 MigratoryB-cell profiling DC temper to predict subcutaneous clinical response immunity following through keyRituximab tolerance therapy 077 antibodyDefective cross-reactivity complement inhibitory to desmoglein function 3 and of rotavirus CD46 predisposes VP6. Michael to pathways.in patients Niroshana with autoimmune Anandasabapathy blistering, Christopher diseases. Sarah Nirschl, Booker Yong, BridgetLiu, Jeffreybullous Tejada pemphigoid. Cho, Christoph Pei Qiao Ellebrecht,, Gang Wang. Christoph Xi’an, Matthias China. Hammers, ShamimBradley, Mollah, Bridget Rachel Neary, E. Chungwen Feder, Pinru Wei, Wu, Ignacio Peter SanzSage andand RonArlene J Feldman. H 078 GopalIncreased Sapparapu, expression James of Crowe NLRP3 and inflammasome Aimee S Payne. in Philadelphia, peripheral blood PA and Sharpe.Atlanta, Boston, GA. MA and New York, NY. Nashville,mononuclear TN. cells in patients with bullous pemphigoid. Hui Fang, Gang 004062 RationaleProtective and role design of mast of a cellsnovel in dendriticdevelopment cell targetedof lupus erythematosus-vaccine for basal 019* NextWang. generation Xi’an, China. T cell receptor sequencing reveals complex T cell celllike carcinoma. skin lesions Karyn in MRL-lpr/lpr Haitz, Steven mice. R Barthel, Yutaka YongInaba Liu,, Takashi Christopher Yoshimasu, 079* dynamicsAlopecia in areata Alopecia skin Areata transcriptome . Annemieke correlates de Jong with, Luzhou disease Xing, severity Ali and Nirschl,Nobuo Ervin Kanazawa Epstein and and Fukumi Niroshana Furukawa. Anandasabapathy. Wakayama, Japan. Boston, MA and Jabbari,response Zhenpeng to treatment. Dai, Vera Ali H Jabbari Price, ,Madeleine Jane E Cerise, Duvic, Julian David Mackay-Wiggan, Norris, 063 Oakland,In vitro skinCA. irritation and potential efficacy of a novel compound for MariaMadeleine Hordinsky, Duvic, Julian Maria Mackay-Wiggan, Hordinsky, Vera Raphael H Price, Clynes David and Norris, Angela Raphael 005 Anlocalized ex vivo treatmentskin model of that psoriasis. combines Meera topical Gujjar skin, Jack penetration Leonard Arbiser, and Th17 Rick Christiano.Clynes and NewAngela York, Christiano. NY; San Francisco, New York, CA; NY;Houston, Houston, TX; TX; Denver, Minneapolis, CO and stimulation.Coulon and Mary Ajay KBedard Banga., StevenAtlanta, Cook, GA and Leandro Cumming, Santos, GA. Jessica Neil, Minneapolis,MN; San Francisco, MN. CA and Denver, CO. 064 CarlosActivity Eduardo of interferons Peredo, Susan beta Hand Smith, gamma Javier in Cote-Sierradermatomyositis and Jon skin Lenn. is 020080 CalcitoninStatus of gene-related classification peptide criteria (CGRP) for amyopathic induces endothelial dermatomyositis cells (EC) . Neelam to Researchcorrelated Triangle with characteristicPark, NC. pathologic features. Hayley Wheeler, Kerri biasKhan Langerhans, Victoria Werth.cell (LC) Philadelphia, antigen presentation PA and Washington, towards aDC. Th17 response Rieger, Chung Lorinda, Kavita Sarin and David F Fiorentino. Redwood City, 081 throughEruptive induction papules inof solublea patient mediators. with connective Wanhong Dingtissue, Lori disease. L Stohl, Naomi 006 Immunomodulatory effects of AM1030, a topical 5-HT2B receptor antagonistCA and Stanford, in development CA. for atopic dermatitis. Niklas Palmqvist, Max JohnDolly A ,Wagner, Sarika Ramachandran. Linghui Xu and NewRichard York, David NY. Granstein. New York, NY. 065 Siller,Treg Andersexpression Sjödin, and Helena function Arozenius, in pemphigus. Christina Ana Wenglén,Maria Roselino Anna-Carin, Celina 021*082* ElevatedExpanded thymic αβ T stromal cell clones lymphopoietin are present inexpression the healed in lesionsthe skin of blocks psoriasis Ryde,Albuquerque, Lars Pettersson, Diego Luis Cecilia Costa, Klint, Aline Anna Turatti Pramhed, and JoaoAnna SantanaLöfdahl Silva.and breastand likely carcinogenesis. represent theShadmehr autoreactive Demehri T ,cells Trevor of Jorigin. Cunningham, Tiago R Matos Sindhu, GunillaRibeirao Ekström. Preto, Brazil.Lund, Sweden. Manivasagam,John Thomas Melissa O’Malley, Meyer, Ahmed David Gehad, Denardo, Jessica Raphael Emberley Kopan Teague, and Wayne Elizabeth 007066* PhenotypicDelineation analysis of ST18 of roledendritic in the cellspathogenesis infiltrating of pemphigusa spontaneous vulgaris. model Yokoyama.Lowry, Harlan St. Louis, Robins, MO Thomas and Cincinnati, S. Kupper, OH. James G Krueger and Rachael ofD. basal Vodo cell, S Geller,carcinoma. E Ben-Asher, Christopher T Olender, Nirschl I, Goldberg,Yong Liu, Pinru J Nosgorodsky, Wu, Karyn A 022 TopicalClark. applicationBoston, MA; ofSeattle, eupatilin WA andameliorates New York, atopic NY. dermatitis-like skin HaitzAlkelai, and P Niroshana Tatarsky, TAnandasabapathy. Zeeli, S Baum, A Barzilai, Boston, I MA.Saleh, D Zillikens, D Lancet, 083 lesionsBullous of pemphigoidNC/Nga mice. autoantibodies Young Min Park and, Ji Hyuncomplement Lee, Ye Jin are Lee required and Jun 008 PotentialO Sarig and mechanisms Eli Sprecher. for Tel loss Aviv, of Israel;hair follicle Rehovot, immune Israel privilege and Luebeck, in youngfor eosinophil Lee. Seoul, localization Korea (the Republicto the dermal-epidermal of). junction. Kelly + patientsGermany. with alopecia areata following hepatitis B vaccination. 023 CD8Messinghamαα T cells, contribute Jeffery W toWang, lichen Heather planus independenceM Holahan, Rupasree of LAMP1- Srikantha, 067 ChristopherAtorvastatin Richardson attenuates, Elaine cholesterol Gilmore andloading Brian induced Poligone. neutrophil Rochester, NY. meditatedSamantha degranulation. Aust and Janet Bing A Fairley. Li, Xiuwen Iowa Sun City, and IA. Gang Wang. Xi’an, 009* CCL17extracellular attenuates traps. tumor Minglin immunity Liu, Muhammad by increasing Bashir, regulatory Kevin Jon T cellsWilliams and 084* China.Collagen XVII autoantibodies are present in Parkinson’s Disease patients Th2and cells Victoria while Werth. decreasing Philadelphia, myeloid-derived PA. suppressor cells in tumor 024 Immunomodulatoryand co-localize with effects tyrosine of hydroxylasenanoparticles in theon thesubstantia contact nigra. Janet 068 microenvironment.Anti-thyroid peroxidase Makoto antibodies Sugaya, Sohshi induce Morimura, similar Tomonorieffects on Oka, hypersensitivityA Fairley, Kelly Messingham, response in C57BL/6Nandakumar hairless Narayanan, mice. Samreen Samantha Jatana Aust,, Hirakukeratinocyte Suga, Tomomitsu cell signaling Miyagaki, as antibodies Yuichiro Tsunemi, directed Yoshihide against desmoglein Asano, 3. BrianJoseph C Palmer Helfenberger, and Lisa MartinA DeLouise. Cassell Rochester, and Stephanie NY. Alberico. Iowa City, IA. YayoiThomas Tada, Sajda Takafumi, Kristina Kadono Seiffert-Sinha and Shinichi and Sato. Animesh Tokyo, A.Japan. Sinha. Buffalo, NY. 025085 CapturingThe Asian functional atopic dermatitis conservation phenotype between combines human featuresskin and ofmouse atopic DC 010069* DistinctiveIL-13 receptor downmodulation alpha 1 downregulation of plasmacytoid as a protective dendritic cellmechanism by vitamin and systemsdermatitis for generating and psoriasis better with vaccines. increased Eynav Th17 Klechevsky polarization.. Saint Shinji Louis, Noda , D3therapeutic analogue in target its interferon- in pemphigus.α production Kristina Seiffert-Sinhaand chemotactic, Elizabeth activity. Zoe MO.Mayte Suarez-Farinas, Kwang Hoon Lee, Kenji Kabashima, James G TakahiroWelch, RamaSuzuki Dey-Rao, Yoshiki Tokura.and Animesh Hamamatsu, A. Sinha. Japan. Buffalo, NY. 026* HumanKrueger skin and is Emmaprotected Guttman-Yassky. by four functionally New York, and NY;phenotypically Seoul, Korea (the 011**070 AComparative wave of regulatory genomic T cells analysis into neonatalin autoimmune skin mediates clusters tolerance with PV. Priya to discreteDemocratic populations People’s of Republicresident of)and and recirculating Kyoto, Japan. memory T cells. Rei commensalSasankan, Saharmicrobes Y Naseer, . Tiffany Kristina C Scharschmidt Seiffert-Sinha, Kimberly and SAnimesh Vasquez, A. Hong-Sinha. 086 WatanabeDiffering, Ahmedpolarization Gehad, of γδChao T cells Yang, following Laura Campbell, topical imiquimod Jessica Emberley AnBuffalo, Truong, NY.Sofia V. Gearty, Mariela L Pauli, Audrey Nosbaum, Michael Teague,associated Victor with Huang, psoriasiform Tiago R Matos, or lupus-like Thomas disease S. Kupper in mice.and Rachael Mehran 071 Otto,Lineage James tracing J Moon, of isotype-specific Abul K. Abbas, Michaelautoantibody A Fischbach repertoires and Michael in Clark.Ghoreishi Boston,, Misha MA. Zarbafian and Jan Peter Dutz. Vancouver, Canada. Davidpemphigus Rosenblum. vulgaris. San EricFrancisco, Milan MukherjeeCA; Bethesda,, Christoph MD and Ellebrecht, Charlestown, Qi 027087 NovelVisualizing STAT3 inhibitorin vivo cuticular LLL12 significantly (eponychial) reduces hemosiderin-containing IL-17, IL-22, and IFN- MA.Zheng, Eun Jung Choi and Aimee Sue Payne. Philadelphia, PA. gammadeposits mRNA in patients expression with in autoimmunepsoriatic PBMCs. connective Justin G tissueHastings diseases, Xiaoli via 012072* KeratinA pathogenic 17 enhances role for the IL-9 chemotaxis in psoriasis: of IL-9neutrophils producing through T cells regulating are frequent Zhang,Prussian Jiayuh blue Lin, and Chenglong dermoscopy. Li and Jeffrey Henry KDon Wong. McBride Columbus,, Richard OH. Sontheimer chemokinein human psoriasisCXCL1 secretion and IL-9 in enhances keratinocytes dermatitis via PI3k/AKT/NF- in two IL-17κB dependent 028* GILT-mediatedand Tracy Frech. processing Oklahoma of aCity, self OK and and melanoma Salt Lake antigenCity, UT. in thymic pathway.mouse models Er-Le Dang of psoriasiform, Liang Jin, Chang-xu dermatitis. Han, Ahmed Bing Li, Gehad Man Jiang, Christoph and 088 epithelialEpigenetic cells downregulation promotes deletion of SFRP4and regulatory contributes T cells.to epidermal Karen Taraszka GangSchlapbach, Wang. Xi’an, Tiago China. R Matos, Jessica Emberley Teague, Victor Huang, Hastingshyperplasia, Matthew in psoriasis. Rausch, Honglin Todd C. Wang Metzger,, Jing Bai.Michael Shanghai, Waterfield, China. Jessica 013* ContributionsElizabeth Lowry, of skinThomas resident S. Kupper and recirculating and Rachael Clark. memory Boston, T cells MA to and 089* CortezIL-7 blockade and Mark prevents S. Anderson. the onset Phoenix, of alopecia AZ and San areata Francisco, . Zhenpeng CA. Dai, depigmentationBern, Switzerland. in vitiligo. Jillian Richmond, Mehdi Rashighi, Priti Luzhou Xing, Ali Jabbari, Raphael Clynes and Angela Christiano. New York, Agarwal and John E Harris. Worcester, MA. NY.

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1 3 76 PPosteroster PPresentationsresentations // abstract titlesitles

Adaptive Immunity & Vaccination 014090 AcneIFN-γ vaccinespathway targeting blockade preventssecretory theCAMP onset factor of alopecia of Propionibacterium areata . Raphael 103 STAT3-dependent VEGF production from keratinocytes abrogates All orals [designated with an asterisk (*)] listed below are presented in the acnes.Clynes ,Chun-Ming Zhenpeng Dai,Huang Luzhou. San Diego,Xing, Ali CA. Jabbari and Angela Christiano. dendritic cell activation and migration by arsenic: a plausible regional Adaptive Immunity & Vaccination Minisymposium on Saturday, May 9, 2015, 015* IdentifyingNew York, NY. Merkel polyomavirus-specific CD4+ and CD8+ T-cells in mechanism of immunosuppression in arsenical cancers. Chien-Hui from 12:30-3:30 pm in Salon D, Hilton Atlanta. Orals designated by two asterisks 091* MerkelAnti-BP180 cell carcinoma IgG4 autoantibodies patients’ tumor-infiltrating are inhibitory in BP lymphocytes.in BP180 Dafina Hong, Chih-Hung Lee, Gwo-Shing Chen, Kee-Lung Chang and Hsin-Su Yu. (**) will be presented during a Plenary Session. Orals designated by three Ibranihumanized, Jayasri mouse G Iyer, model. Natalie Zhi Vandeven, Liu, Yagang Natalie Zuo, Miller,Flor Evangelista, Olga Afanasiev, Antonio Kaohsiung, Taiwan; Taipei, Taiwan and Zhunan, Taiwan. asterisks (***) will be presented during the Interdisciplinary Spotlight: Skin DavidGuilabert, Koelle Ning and Li Paul and Nghiem. Luis A. Diaz. Seattle, Chapel WA. Hill, NC and Barcelona, Spain. 104 Plexin-B1 and semaphorin 4D cooperate to promote cutaneous Cancer Minisymposium on Friday, May 8, 2015, from 2:00 – 5:00 pm in the Grand 016*092* RegulatoryPemphigus T foliaceus cells facilitate patients cutaneous have IgG4 wound antibodies healing. thatAudrey recognize Nosbaum Amb, squamous cell carcinoma cell proliferation, apoptosis, migration and Ballroom, Hilton Atlanta. Monikaa 1, a component Ettinger, fromHong-An short Truong, ragweed Mariela pollen L allergen.Pauli, Sofia Ye V. Qian Gearty,, Joseph Abul K. invasion. Chen Zhang, Wei Li. Xi’an, China. AbbasS-Y Jeong and and Michael Luis A. David Diaz. Rosenblum. Chapel Hill, San NC. Francisco, CA. 105 Immunosuppression and ethnicity influence keratinocyte differentiation + + 001 RON2315: A novel human biologic for the topical treatment of psoriasis. 017093* QuantificationT-bet-deficient ofmice CD69areCD103 protected skin TfromRM cells imiquimod-induced in chronic atopic dermatitis.psoriasis- in kidney transplant recipients. Jodi L Johnson, Kathleen J Green, John J. Thomas Gadek. Portola Valley, CA. SeoHyeonglike dermatitis KIM, Changdue to Ookthe Park,protective Jung U IL-4 Shin, producing Ji Yeon Noh, NKT Shan cells. Qing- Jin, Friedewald and June Robinson. Chicago, IL. 002* Blockade for CD155-TIGIT interaction is an effective therapy for HeminSheng MiLee,, Dinghong Jungsoo Lee, Wu, Thomas Ling Han, S. JingwenKupper andDeng, Kwang Li Zhou Hoon and Lee. Chuanjian Seoul, 106* Identification of a pre-programmed metastasis-associated homozygous melanoma. Takashi Inozume, Tomonori Yaguchi, Yutaka Kawakami and KoreaLu. Guangzhou, (the Republic China of) and and Detroit, Boston, MI. MA. deletion in Chr2q37.3 in human melanoma. Kasey L Couts, Ichiro Shinji Shimada. Chuo, Japan and Shinjyuku, Japan. 018*094 SharedA novel VH1-46 pathway antibody regulating gene tolerance usage in ofpemphigus peripheral vulgaris B lymphocytes predicts . Nakachi, Yuchun Luo, Hieu Van, Akihiro Fujisawa, Steven Robinson, 003 Migratory DC temper subcutaneous immunity through key tolerance antibodyNeda Nikbakht cross-reactivity, Timothy Manser. to desmoglein Philadelphia, 3 and PA. rotavirus VP6. Michael William Robinson, Mark Geraci and Mayumi Fujita. Aurora, CO and pathways. Niroshana Anandasabapathy, Christopher Nirschl, Yong Liu, 095 JeffreyImmunologic Tejada signaturesCho, Christoph in Tregs Ellebrecht, and Teffectors Christoph in Matthias psoriasis. CatherineHammers, Denver, CO. Shamim Mollah, Rachel E. Feder, Pinru Wu, Peter Sage and Arlene H GopalMaiKhanh Sapparapu, Nguyen James, Melissa Crowe Danesh, and Aimee Kourosh S Payne. Beroukhim, Philadelphia, Margaret PA Lowe, and 107 Sestrin2 positively regulates AKT signaling and survival in human Sharpe. Boston, MA and New York, NY. Nashville,Keyon Taravati, TN. Wilson Liao and Michael David Rosenblum. San Francisco, squamous cell carcinoma and melanoma cells. Palak Shah, Baozhong 004 Rationale and design of a novel dendritic cell targeted vaccine for basal 019* NextCA; Irvine, generation CA and T Loscell Angeles, receptor CA. sequencing reveals complex T cell Zhao, Andrey Budanov, Lei Qiang, Mei Ming, Andrew Aplin, Diane Sims cell carcinoma. Karyn Haitz, Steven R Barthel, Yong Liu, Christopher dynamics in Alopecia Areata . Annemieke de Jong, Luzhou Xing, Ali and Yu-Ying He. Chicago, IL; Richmond, VA and Philadelphia, PA. Nirschl, Ervin Epstein and Niroshana Anandasabapathy. Boston, MA and Jabbari, Zhenpeng Dai, Vera H Price, Madeleine Duvic, David Norris, 108* Neurofibroma development is dependent on the presence of peripheral Oakland, CA. Maria Hordinsky, Julian Mackay-Wiggan, Raphael Clynes and Angela neurons in the tumor microenvironment. Chung-Ping Liao, Sanjay 005 An ex vivo skin model that combines topical skin penetration and Th17 CarcinogenesisChristiano. New & York, Cancer NY; San GeneticsFrancisco, CA; Houston, TX; Denver, CO and Pradhan, Zhiguo Chen, Amish J. Patel, Chiachi Liu, Reid C. Booker and Lu stimulation. Mary Bedard, Steven Cook, Leandro Santos, Jessica Neil, All oralsMinneapolis, [designated withMN. an asterisk (*)] listed below are presented in the Q. Le. Dallas, TX. Carlos Eduardo Peredo, Susan H Smith, Javier Cote-Sierra and Jon Lenn. 020Carcinogenesis Calcitonin & Cancergene-related Genetics peptide Minisymposium (CGRP) induces on Thursday, endothelial May cells7, 2015, (EC) to 109 Insulin-like growth factor II mRNA-binding protein 3 expression predicts Research Triangle Park, NC. from 2:00-5:00bias Langerhans pm in the cell Grand (LC) Ballroom,antigen presentationHilton Atlanta. towards Orals designated a Th17 response by unfavorable prognosis in acral lentiginous melanoma. Shiou-Hwa Jee, Yi- two asterisksthrough (**) induction will be presented of soluble during mediators. a Plenary Wanhong Session. Ding Orals, Lori designated L Stohl, by Shuan Sheen, Chih-Chun Yeh, Pin-Chun Chen, Min-Liang Kuo and Chia-Yu 006 Immunomodulatory effects of AM1030, a topical 5-HT2B receptor antagonist in development for atopic dermatitis. Niklas Palmqvist, Max three asterisksJohn A Wagner,(***) will Linghui be presented Xu and Richardduring the David Interdisciplinary Granstein. New Spotlight: York, NY. Skin Chu. Taipei, Taiwan. Siller, Anders Sjödin, Helena Arozenius, Christina Wenglén, Anna-Carin 021*Cancer MinisymposiumElevated thymic onstromal Friday, lymphopoietin May 8, 2015, from expression 2:00 – 5:00in the pm skin in theblocks Grand 110*** Genomic drivers of cutaneous squamous cell carcinoma development . Ryde, Lars Pettersson, Cecilia Klint, Anna Pramhed, Anna Löfdahl and Ballroom,breast Hilton carcinogenesis. Atlanta. Shadmehr Demehri, Trevor J Cunningham, Sindhu Vida Chitsazzadeh, C Coarfa, T Nguyen, A K Joseph, P Gunaratne, X Su, D A Gunilla Ekström. Lund, Sweden. Manivasagam, Melissa Meyer, David Denardo, Raphael Kopan and Wayne Wheeler, E R Flores and Kenneth Tsai. Houston, TX and Pasadena, TX. 007 Phenotypic analysis of dendritic cells infiltrating a spontaneous model 096 Yokoyama.Lessons from St. Louis,melanoma MO and applied Cincinnati, to other OH. cancers: DC-HIL is a potential 111*** Basal cell carcinoma originates from multiple stem cell lineages within of basal cell carcinoma. Christopher Nirschl, Yong Liu, Pinru Wu, Karyn 022 Topicalbiomarker application and treatment of eupatilin target forameliorates breast and atopic colon dermatitis-like cancer. David B skin hair follicle and mechanosensory touch dome epithelia. Sunny Wong, Haitz and Niroshana Anandasabapathy. Boston, MA. lesionsHarker, ofJake NC/Nga E Turrentine, mice. Young Jin-Sung Min ParkChung,, Ji HyunPonciano Lee, DYe Cruz Jin Leeand andKiyoshi Jun Shelby C Peterson and Andrzej Dlugosz. Ann Arbor, MI. 008 Potential mechanisms for loss of hair follicle immune privilege in youngAriizumi. Lee. Dallas, Seoul, TX. Korea (the Republic of). 112 Premature menopause and hematologic neoplasms further characterize + patients with alopecia areata following hepatitis B vaccination. 023097 CD8DLX3-dependentαα T cells contribute p53 signaling to lichen network planus controls independence keratinocyte of LAMP1- cell cycle xeroderma pigmentosum as a disorder of accelerated aging. John J Christopher Richardson, Elaine Gilmore and Brian Poligone. Rochester, NY. meditatedand squamous degranulation. tumor growth. Bing MeghanLi, Xiuwen D SunKellett and, Elisabetta Gang Wang. Palazzo, Xi’an, DiGiovanna, Deborah Tamura, Melissa Merideth, Sikandar G. Khan, Divya 009* CCL17 attenuates tumor immunity by increasing regulatory T cells and China.Christophe Cataisson, Anna Gormley, Paul Bible, Valentina Pietroni, Angra and Kenneth H Kraemer. Bethesda, MD. Th2 cells while decreasing myeloid-derived suppressor cells in tumor 024 ImmunomodulatoryNadezda Radoja, Joonsung effects Hwang, of nanoparticles Miroslav Blumenberg, on the contact Stuart H Yuspa 113 FRA1 plays an essential role in skin, head and neck cancer cell growth microenvironment. Makoto Sugaya, Sohshi Morimura, Tomonori Oka, hypersensitivityand Maria Morasso. response Bethesda, in C57BL/6 MD and hairlessNew York mice. City, Samreen NY. Jatana, and migration . Jennifer Y Zhang, Xiaoling Zhang, Joseph Wu and Terry Hiraku Suga, Tomomitsu Miyagaki, Yuichiro Tsunemi, Yoshihide Asano, 098* BrianPeriostin C Palmer is a keyand nicheLisa A component DeLouise. Rochester, for melanoma NY. wound metastasis. Lechler. Durham, NC. Yayoi Tada, Takafumi Kadono and Shinichi Sato. Tokyo, Japan. 025 CapturingKeitaro Fukuda functional, Eiji Sugihara, conservation Shoichiro between Ohta, Kenji human Izuhara, skin Takeruand mouse DC 114** Cutaneous neoplasms undergo a dynamic immunoediting process. 010 Distinctive downmodulation of plasmacytoid dendritic cell by vitamin systemsFunakoshi, for Masayukigenerating Amagai better and vaccines. Hideyuki Eynav Saya. Klechevsky Tokyo, Japan. Saint and Louis, Saga, Bradley J Kubick, Dennis R Roop. Aurora, CO. D3 analogue in its interferon-α production and chemotactic activity. MO.Japan. 115* Smoothened (SMO) resistance is driven by PI3K–Akt signaling in a Takahiro Suzuki, Yoshiki Tokura. Hamamatsu, Japan. 026*099 HumanA zebrafish skin is modelprotected for investigating by four functionally the role andof phenotypicallySOX10 in invasive subset of murine ASZ001 BCC cells displaying tumor-initiating cell (TIC)- 011** A wave of regulatory T cells into neonatal skin mediates tolerance to discretemelanoma populations . Andrea L Suarezof resident. New and York, recirculating NY. memory T cells. Rei like characteristics . Guang C Jin, Yucui Zhu, Arianna Kim and David R commensal microbes . Tiffany C Scharschmidt, Kimberly S Vasquez, Hong- 100 WatanabeReceptor tyrosine, Ahmed kinaseGehad, inhibitor, Chao Yang, Dasatinib, Laura Campbell, inhibits Jessica activity Emberley of Bickers. New York, NY. An Truong, Sofia V. Gearty, Mariela L Pauli, Audrey Nosbaum, Michael Teague,endogenous Victor EphB2 Huang, receptor Tiago R andMatos, promotes Thomas apoptosis S. Kupper of and cutaneous Rachael 116 Haploinsufficiency of the Ptch1 gene predisposes mice to developing IR- Otto, James J Moon, Abul K. Abbas, Michael A Fischbach and Michael Clark.squamous Boston, carcinoma MA. cells. Mehdi Farshchian, Liisa Nissinen, Reidar induced BCCs. Grace Ying Wang, Eileen Libove, Danielle Tucker and Ervin David Rosenblum. San Francisco, CA; Bethesda, MD and Charlestown, 027 NovelGrénman STAT3 and inhibitor Veli-Matti LLL12 Kähäri. significantly Turku, Finland. reduces IL-17, IL-22, and IFN- Epstein. Oakland, CA. MA. 101 gammaCirculating mRNA cell-free expression DNA isin increasedpsoriatic inPBMCs. sera Justinof Sézary G syndromeHastings, Xiaoli 117 Slow-cycling cells in cutaneous T-cell lymphoma: A dynamic 012 Keratin 17 enhances the chemotaxis of neutrophils through regulating Zhang,patients. Jiayuh Zuolin Lin, Ying Chenglong, Timothy Li Langridge,and Henry MadeleineK Wong. Columbus, Duvic and OH. Xiao Ni. subpopulation with reduced chemosensitivity and increased chemokine CXCL1 secretion in keratinocytes via PI3k/AKT/NF-κB 028* GILT-mediatedHouston, TX. processing of a self and melanoma antigen in thymic tumorigenic potential. Stefan M Schieke, Wasakorn Ten Kittipongdaja and pathway. Er-Le Dang, Liang Jin, Chang-xu Han, Bing Li, Man Jiang and 102 epithelialSphingosine-1-phosphate cells promotes deletion stimulating and regulatory CAMP overexpression T cells. Karen Taraszkaaccelerates Xuesong Wu. Milwaukee, WI. Gang Wang. Xi’an, China. Hastingsdevelopment, Matthew of cutaneous Rausch, SCC.Todd YoshikazuC. Metzger, Uchida Michael, Kyungho Waterfield, Park, YoungJessica 118* Evidence for reciprocal interaction between bone marrow and 013* Contributions of skin resident and recirculating memory T cells to CortezIl Kim, andAnna Mark Nielsen-Scott, S. Anderson. Kyong-Oh Phoenix, Shin, AZ and Yong-Moon San Francisco, Lee, CA.Walter M. cutaneous epithelial cells. Rebecca Jane Morris, Kelly Johnson, Kelsey depigmentation in vitiligo. Jillian Richmond, Mehdi Rashighi, Priti Holleran, Sarah Arron, Theodora Mauro and Peter M Elias. San Francisco Boland, Nyssa Readio, Heuijoon Park, Derek Gordon and Douglas Agarwal and John E Harris. Worcester, MA. and Cheongju, Korea (the Republic of). Londono. Austin, MN and Piscataway, NJ.

Notes: Notes:

77 1 4 PPosteroster P Presentationsresentations / /a abstractbstract t titlesitles

Adaptive119 The role Immunity of perlecan in the& Vaccination path to malignancy. Kathleen Cook Suozzi, 014136 AcneGenome-stabilization vaccines targeting secretoryby STAT1-induced CAMP factor cancer of cellPropionibacterium senescence. All orals [designatedGiovanni Zito, with Christine an asterisk J. Ko, (*)] Don listed X Nyugenbelow areand presented Valentina in Greco. the New acnes.Martin Chun-Ming Röcken, Ellen Huang Brenner,. San Diego, Heidi CA. Braumüller, Thomas Wieder, Diana AdaptiveHaven, Immunity CT. & Vaccination Minisymposium on Saturday, May 9, 2015, 015* IdentifyingGransheier andMerkel Jürgen polyomavirus-specific Bauer. Tübingen, Germany. CD4+ and CD8+ T-cells in from120*** 12:30-3:30 Rolling pmthe ingenetic Salon D,dice: Hilton Neutral Atlanta. and Orals deleterious designated SMO by mutationstwo asterisks in 137 MerkelRapamycin cell carcinoma is a chemopreventive patients’ tumor-infiltrating and chemotherapeutic lymphocytes. agent Dafina for (**) will bedrug-resistant presented during basal a cell Plenary carcinoma. Session. Scott Orals Atwood designated, Kavita by Sarin, three Jiang Li, IbraniRAS-driven, Jayasri epidermalG Iyer, Natalie squamous Vandeven, cell Nataliecarcinoma: Miller, Evidence Olga Afanasiev, from mouse asterisks (***)Catherine will be Yao, presented Nicole M during Urman, the Anne Interdisciplinary Lynn Su Chang, Spotlight: Jean Y TangSkin and Davidmodels. Koelle Christophe and Paul Nghiem.Cataisson Seattle,, Hiroshi Kitagawa,WA. Christine Hollander, Cancer MinisymposiumAnthony Oro. Stanford, on Friday, CA. May 8, 2015, from 2:00 – 5:00 pm in the Grand 016* RegulatoryPhillip A Dennis T cells andfacilitate Stuart cutaneous H Yuspa. Bethesda, wound healing. MD and Audrey Baltimore, Nosbaum MD., Ballroom,121 Identification Hilton Atlanta. of a role for CSL and PDCD4 interaction in control of 138 MonikaWhole Ettinger, genome sequencing Hong-An Truong, reveals Mariela oncogenic L Pauli, mutations Sofia V. inGearty, mycosis Abul K. fibroblast cell senescence and cancer-associated fibroblast activation. Abbasfungoides and Michael . Laura DavidYoung Rosenblum. McGirt, Peilin San Jia, Francisco, Devin Baerenwald, CA. Robert J + + 001 RON2315:Seunghee A Jo novel, Yang human Sui Brooks biologic and forGian the Paolo topical Dotto. treatment Charlestown, of psoriasis. MA. 017 QuantificationDuszynski, John ofA Zic, CD69 CD103Jeffrey skinZwerner, TRM cells Zhongming in chronic Zhao atopic and dermatitis.Christine M 122 ThomasLoss of Gadekthe autophagy. Portola Valley, repressor CA. p8 in human dermal fibroblasts causes SeoHyeongEischen. Charlotte, KIM, Chang NC Ook and Park, Nashville, Jung U TN. Shin, Ji Yeon Noh, Shan Jin, 002* Blockadesenescence for CD155-TIGITand CAF activation. interaction Sandro is anGoruppi effective Goruppi therapy, Gian for Paolo 139 HeminDown-regulation Lee, Jungsoo Lee,of receptor Thomas type S. Kupper protein and tyrosine Kwang Hoonphosphatase-kappa Lee. Seoul, melanoma.Dotto. Charlestown, Takashi Inozume MA and, Tomonori Lausanne, Yaguchi, Switzerland. Yutaka Kawakami and Koreapromotes (the Republic squamous of) andcell carcinoma.Boston, MA. Yiru Xu, Hanjun Yang, Yang Xu, Jin 123* ShinjiTumor-intrinsic Shimada. Chuo, PD-1 Japan signaling and promotesShinjyuku, MerkelJapan. cell carcinoma growth. 018* SharedZhou, VH1-46Kristin antibodyRybski, John gene J Voorhees usage in andpemphigus Gary J Fisher. vulgaris Ann predicts Arbor, MI. 003 MigratorySonja Kleffel DC ,temper Christian subcutaneous Posch, Stephen immunity Fucaloro, through Margot key C toleranceJoubert, 140 antibodyCytokine-induced cross-reactivity senescence to desmoglein in human 3cancer and rotavirus cells critically VP6. Michael involves pathways.Manisha Thakuria,Niroshana Thomas Anandasabapathy S. Kupper and, Christopher Tobias Schatton. Nirschl, YongBoston, Liu, MA. JeffreyAgo2. TejadaMartin Cho Röcken, Christoph, Heidi Ellebrecht, Braumüller, Christoph Jana Pahl, Matthias Thomas WiederHammers, and 124* ShamimUpregulation Mollah, ofRachel pro-oncogenic E. Feder, Pinru Fbxw7 Wu, substrates Peter Sage in andMerkel Arlene cell H GopalEllen Sapparapu, Brenner. Tübingen, James Crowe Germany. and Aimee S Payne. Philadelphia, PA and Sharpe.carcinoma Boston, Monique MA and Elise New Verhaegen York, NY., Doris Mangelberger, Ehab Nazzal, 141 Nashville,Planar cell TN. polarity effector gene INTU mediates the formation of 004 RationaleKristin Rybski, and designJack Weick,of a novel Tracy dendriticVozheiko, cellDawn targeted Wilbert vaccine and Andrzej for basal 019* Nextbasal generation cell carcinoma T cell throughreceptor orchestrating sequencing reveals ciliogenesis complex and T cellHedgehog cellDlugosz. carcinoma. Ann Arbor, Karyn MI.Haitz, Steven R Barthel, Yong Liu, Christopher dynamicssignaling in Ning Alopecia Yang, AreataChengbao . Annemieke Liu, Li Li, Jamesde Jong E, Fitzpatrick,Luzhou Xing, Evan Ali C Jones, 125 Nirschl,Increased Ervin mutant Epstein p53 and keratinocyte Niroshana Anandasabapathy. clonal expansion Boston, and intraepidermal MA and Jabbari,David Norris,Zhenpeng Aimin Dai, Liu, Vera Richard H Price, August Madeleine Clark, Duvic,Dennis David R Roop, Norris, Kenneth R Oakland,levels of CA. IL-22 and NOS2 in the presence of LC in chronically ultraviolet MariaShroyer Hordinsky, and Jiang Julian Chen. Mackay-Wiggan, Stony Brook, NY; Raphael Beijing, Clynes China; and Aurora, Angela CO and 005 AnB (UVB)ex vivo irradiated skin model skin. that Christina combines Bürgler topical, Julia skin Lewis penetration and Michael and Girardi.Th17 Christiano.University Park,New York, PA. NY; San Francisco, CA; Houston, TX; Denver, CO and stimulation.New Haven, Mary CT. Bedard, Steven Cook, Leandro Santos, Jessica Neil, 142 Minneapolis,Bmi-1 differentially MN. regulates p16ink4a and p19arf in p63-overexpressing 126 CarlosRapamycin Eduardo alters Peredo, the metabolicSusan H Smith, phenotype Javier Cote-Sierrain human cutaneous and Jon Lenn. T-cell 020 Calcitoninkeratinocytes. gene-related Wendy peptideC Weinberg (CGRP), Roshini induces Manel endothelial Ponnamperuma, cells (EC) Linan to Researchlymphoma. Triangle Wasakorn Park, NC. Ten Kittipongdaja, Xuesong Wu, Sam Hwang and biasHa, Langerhans Devin Reilly cell and (LC) Steve antigen Jay. Silver presentation Spring, MD towards and Bethesda, a Th17 MD.response Stefan M Schieke. Milwaukee, WI. 143 throughA subpopulation induction ofof solubleepidermal mediators. squamous Wanhong cell carcinoma Ding, Lori stem L Stohl, cells 006 Immunomodulatory effects of AM1030, a topical 5-HT2B receptor 127 antagonistComplement in development C5a regulates for squamous atopic dermatitis. carcinogenesis. Niklas PalmqvistTerry R Medler, Max, Johndrives A Wagner, formation Linghui of rapidly-growing Xu and Richard Davidand highly-vascularized Granstein. New York, aggressive NY. Siller,Alexandra Anders M. Sjödin, Forsyth Helena and Lisa Arozenius, M. Coussens. Christina Portland, Wenglén, OR. Anna-Carin 021* Elevatedtumors. thymic Richard stromal Eckert ,lymphopoietin Gautam Adhikary, expression Dan Grun in and the Wenskin Xu.blocks 128* Ryde,A counter-intuitive Lars Pettersson, role Cecilia for caspaseKlint, Anna 3 in Pramhed, promoting Anna genetic Löfdahl instability and breastBaltimore, carcinogenesis. MD. Shadmehr Demehri, Trevor J Cunningham, Sindhu Gunillaand skin Ekström. carcinogenesis. Lund, Sweden. Xinjian Liu. Durham, NC. 144 Manivasagam,Keratin-dependent Melissa regulationMeyer, David of Denardo, autoimmune Raphael regulator Kopan (Aire)and Wayne and gene 007129 PhenotypicDownregulation analysis of of miR-215dendritic enhances cells infiltrating cancer cell a migrationspontaneous and invasionmodel Yokoyama.expression St. in Louis, skin MOtumor and keratinocytes. Cincinnati, OH. Ryan Hobbs, Daryle DePianto, ofin basal cutaneous cell carcinoma. squamous Christopher cell carcinoma. Nirschl Zelmira, Yong Liu,Lazarova Pinru, Wu,Edit KarynB Olasz, 022 TopicalJustin application Jacob, Minerva of eupatilin Han, Byung-Min ameliorates Chung, atopic Adriana dermatitis-like Batazzi, SuFey skin Ong, HaitzBasia and M Michalski,Niroshana NathanAnandasabapathy. Duncan, Ashley Boston, M Schock, MA. Jozef Lazar and lesionsWenxin of Zheng,NC/Nga Janis mice. Marie Young Taube, Min ParkDaniela, Ji Hyun Cˇ iháková, Lee, Ye Fengyi Jin Lee Wan and and Jun 008 PotentialMarcy Neuburg. mechanisms Milwaukee, for loss WI. of hair follicle immune privilege in youngPierre Lee. Coulombe. Seoul, Korea Baltimore, (the Republic MD. of). + 130 patientsSerum exosomes with alopecia from areatametastatic following basal hepatitis cell carcinoma B vaccination. patients confer 023145* CD8Identificationαα T cells contribute of the toKNSTRN lichen proteome planus independence by APEX2 targeting. of LAMP1- Carolyn Lee, Christopherincreased metabolicRichardson activity, Elaine Gilmorein cultured and primaryBrian Poligone. human Rochester,fibroblasts. NY. meditatedAngela Mah, degranulation. Christie Nguyen Bing Liand, Xiuwen Paul Khavari.Sun and Stanford,Gang Wang. CA Xi’an,and Palo 009* CCL17Gefei attenuatesZhu, Travis Antes,tumor Robertimmunity Spitale by increasing and Anne Lynnregulatory Su Chang. T cells Redwood and China.Alto, CA. Th2City, cells CA; while Mountainview, decreasing CA myeloid-derived and Irvine, CA. suppressor cells in tumor 024146 ImmunomodulatoryDeficiency of soluble effects adenylyl of nanoparticles cyclase facilitates on the carcinogenesis. contact 131 microenvironment.Mitochondrial DNA Makoto damage Sugaya in Asian, Sohshi patients Morimura, with non-melanomaTomonori Oka, skin hypersensitivityJonathan Hale Zippin response, Lavo in Ramos,C57BL/6 Ana hairless Diaz, Charléemice. Samreen Audrey Jatana Nardin,, Hirakucancer. Suga, Byungho Tomomitsu Oh, Zhenlong Miyagaki, Zheng, Yuichiro Jimyung Tsunemi, Seo Yoshihideand Keeyang Asano, Chung. BrianFiona C PalmerM Shaw, and Taha Lisa Merghoub, A DeLouise. Jedd Rochester, Wolchok, NY. Costas Lyssiotis, Lewis C YayoiSeoul, Tada, Korea Takafumi (the Republic Kadono of). and Shinichi Sato. Tokyo, Japan. 025 CapturingCantley, Lonnyfunctional Levin conservationand Jochen Buck. between New York, human NY. skin and mouse DC systems for generating better vaccines. Eynav Klechevsky. Saint Louis, 010132 DistinctiveA new functional downmodulation validation ofassay plasmacytoid to measure dendriticresistance cell drivers by vitamin in 147 Non-migratory Candida albicans-specific CD4 RMT that produce abundant D3patient analogue BCCs. in Ramonits interferon- Whitsonα ,production Scott Atwood, and Kavitachemotactic Sarin, Jiang activity. Li, MO.IL-17 are generated after cutaneous C. albicans infection. Thomas S. TakahiroGeurim SuzukiKim, Melika, Yoshiki Rezaee, Tokura. Mina Hamamatsu, Sarah Ally, Japan. Catherine Yao, Anne Lynn Su 026* HumanKupper skin, Chang is protected Ook Park, by Ryan four Ofunctionally Emerson, Xiaodong and phenotypically Jiang, Tian Tian, John 011** AChang, wave of Jean regulatory Y Tang and T cells Anthony into neonatal Oro. Irvine, skin CA mediates and Stanford, tolerance CA. to discreteThomas populations OMalley, Rachael of resident Clark andand recirculatingRobert C. Fuhlbrigge. memory Boston, T cells. Rei MA and 133 commensalNOTCH1 inhibition microbes .disrupts Tiffany formation C Scharschmidt of stratified, Kimberly Sepithelium Vasquez, inHong- WatanabeSeattle, , AhmedWA. Gehad, Chao Yang, Laura Campbell, Jessica Emberley Anorganotypic Truong, Sofia cell V.culture Gearty, models Mariela of L thePauli, skin. Audrey Lionel Nosbaum, Brooks, Homayoun Michael 148 Teague,Dysregulation Victor Huang, of soluble Tiago Radenylyl Matos, cycaseThomas leads S. Kupper to melanocyte and Rachael Otto,Moslehi, James Lauren J Moon, Alyssa Abul Ing K. andAbbas, Sarah Michael Arron. ASan Fischbach Francisco, and CA. Michael Clark.transformation. Boston, MA. Charlée Audrey Nardin, Michelle Park, Antonella 134* DavidMutation Rosenblum. burden San is Francisco,associated CA;with Bethesda, gender andMD survivaland Charlestown, in metastatic 027 NovelBacchiocchi, STAT3 inhibitor Ruth Halaban LLL12 significantlyand Jonathan reduces Hale Zippin. IL-17, Besançon, IL-22, and France; IFN- MA.melanoma. Sameer Gupta, Mykyta Artomov, William Goggins, Mark Daly gammaNew York, mRNA NY expression and New Haven, in psoriatic CT. PBMCs. Justin G Hastings, Xiaoli 012 Keratinand Hensin 17 enhances Tsao. Boston, the chemotaxis MA and Shatin, of neutrophils Hong Kong. through regulating 149 Zhang,Triazole Jiayuh antifungal Lin, Chenglong agents Lipromote and Henry UV-DNA K Wong. damage Columbus, by increasing OH. 135* chemokineLack of resistant CXCL1 secretionSMO mutations in keratinocytes and decreased via PI3k/AKT/NF-mutationalκ Bload 028* GILT-mediatedoxidative stress. processing Michael of Gober a self, Hasanand melanoma Bashir, Andrew antigen Huang, in thymic JiLon Li, C pathway.of Gorlin-associated Er-Le Dang, Liang basal Jin, cell Chang-xu cancers explainHan, Bing marked Li, Man response Jiang and to epithelialMarshall, cells Vivian promotes Lee, Todd deletion William and Ridky regulatory and John T Seykora.cells. Karen Philadelphia, Taraszka Gangsmoothened Wang. Xi’an, inhibitors. China. Kavita Sarin, Melika Rezaee, Prajakta Jaju, Anne HastingsPA. , Matthew Rausch, Todd C. Metzger, Michael Waterfield, Jessica 013* ContributionsLynn Su Chang, of Anthony skin resident Oro, Ervinand recirculating Epstein and Jean memory Y Tang. T cellsStanford, to CA Cortez and Mark S. Anderson. Phoenix, AZ and San Francisco, CA. depigmentationand Oakland, CA. in vitiligo. Jillian Richmond, Mehdi Rashighi, Priti Agarwal and John E Harris. Worcester, MA.

Notes:Notes:

1 5 78 PPosteroster PPresentationsresentations // abstract titlesitles

Adaptive Immunity & Vaccination 014150 AcneCombinatorial vaccines targeting targeting secretoryof Akt1 and CAMP SMO factor synergistically of Propionibacterium suppresses 161 Interferon-gamma treatment for children with recurrent eczema All orals [designated with an asterisk (*)] listed below are presented in the acnes.the growth Chun-Ming of UV-induced Huang. San BCCs Diego, in a murineCA. model of basal cell nevus herpeticum: a retrospective review. Kavita Darji, Elaine Siegfried. St. Adaptive Immunity & Vaccination Minisymposium on Saturday, May 9, 2015, 015* Identifyingsyndrome. AriannaMerkel Kimpolyomavirus-specific, Yucui Zhu, Nathan PCD4+ Yardley, and MohammadCD8+ T-cells Atharin Louis, MO. from 12:30-3:30 pm in Salon D, Hilton Atlanta. Orals designated by two asterisks Merkeland David cell R carcinoma Bickers. New patients’ York, NY tumor-infiltrating and Birmingham, AL.lymphocytes. Dafina 162 Levamisole-laced cocaine induced vasculitis. Rachel Kapelow. Coolidge, (**) will be presented during a Plenary Session. Orals designated by three 151 IbraniResponse, Jayasri to MAL-basedG Iyer, Natalie PDT Vandeven, in primary Natalie fibroblasts Miller, isolated Olga Afanasiev, from Antigua and Barbuda. asterisks (***) will be presented during the Interdisciplinary Spotlight: Skin DavidXeroderma Koelle Pigmentosumand Paul Nghiem. (XP) Seattle, and Gorlin WA. Syndrome (GS) patients. 163 Different effect of oral cyclosporin therapy and oral anti-histaminergic Cancer Minisymposium on Friday, May 8, 2015, from 2:00 – 5:00 pm in the Grand 016* RegulatoryAngeles Juarranz T cells, Aliciafacilitate Zamarrón, cutaneous Silvia wound Lucena, healing. Salvador Audrey Gonzalez, Nosbaum , therapy to serum high sensitivity-C reactive protein level and thymus Ballroom, Hilton Atlanta. MonikaYolanda Ettinger, Gilaberte, MarcelaHong-An DelTruong, Rio and Mariela Fernando L Pauli, Larcher. Sofia V.Madrid, Gearty, Spain Abul K. and activation regulated chemokine level in patients with adulthood Abbasand Huesca, and Michael Spain. David Rosenblum. San Francisco, CA. atopic dermatitis. Tsutomu Ohtsuka. Nasushiobara, Japan. + + 001 RON2315: A novel human biologic for the topical treatment of psoriasis. 017152 QuantificationThe role of the hemidesmosomal of CD69 CD103 skin protein TRM cells BP180 in chronic in melanoma atopic dermatitis. 164 Retrospective study comparing outcomes among patients receiving Thomas Gadek. Portola Valley, CA. SeoHyeongprogression KIM in vivo., Chang Bin-Jin Ook HwangPark, Jung, Zhen U Shin,Liu, Jaime Ji Yeon Brozowski, Noh, Shan Lin Jin, Lin, rituximab vs conventional adjuvant therapy for pemphigus vulgaris. 002* Blockade for CD155-TIGIT interaction is an effective therapy for HeminNing Li, Lee, Maureen Jungsoo Su, Lee, Nancy Thomas E Thomas, S. Kupper Luis andA. Diaz Kwang and HoonZhi Liu. Lee. Chapel Seoul, Ashwin Agarwal, Russell P Hall and Adela Cardones. Durham, NC. + melanoma. Takashi Inozume, Tomonori Yaguchi, Yutaka Kawakami and KoreaHill, NC. (the Republic of) and Boston, MA. 165* Early pediatric atopic dermatitis shows only a CLA Th2/Th1 + Shinji Shimada. Chuo, Japan and Shinjyuku, Japan. 018*153 SharedComparative VH1-46 evaluationantibody gene of gene usage expression in pemphigus induced vulgaris by RAS predicts oncogenic imbalance, while adults acquire CLA Th22 activation. Hitokazu Esaki, 003 Migratory DC temper subcutaneous immunity through key tolerance antibodyalleles in mousecross-reactivity and human to keratinocytes. desmoglein 3 Luoweiand rotavirus Li, Christophe VP6. Michael Tali Czarnowicki, Juana Gonzalez, Dana Malajian, Sreya Talasila, Adam pathways. Niroshana Anandasabapathy, Christopher Nirschl, Yong Liu, JeffreyCataisson, Tejada Brttany Cho, ChristophFlowers, AleksandraEllebrecht, ChristophMichalowski Matthias and Stuart Hammers, H Yuspa. Berry, Jayla Gray, Shinji Noda, James G Krueger, Amy S. Paller and Emma Shamim Mollah, Rachel E. Feder, Pinru Wu, Peter Sage and Arlene H GopalBethesda, Sapparapu, MD. James Crowe and Aimee S Payne. Philadelphia, PA and Guttman-Yassky. New York, NY and Chicago, IL. Sharpe. Boston, MA and New York, NY. 154 Nashville,Inhibition TN. of the IGF-1R sensitizes human skin to UVB-induced 166 Immune function in children with severe inflammatory skin disease: A 004 Rationale and design of a novel dendritic cell targeted vaccine for basal 019* Nextalterations generation consistent T cell receptorwith actinic sequencing keratosis. reveals Dan F Spandau complex, SunilT cell S. retrospective analysis. Stephanie Frisch, Elaine Siegfried. Peoria, IL and cell carcinoma. Karyn Haitz, Steven R Barthel, Yong Liu, Christopher dynamicsTholpady, inJonathan Alopecia Weyerbacher, Areata . Annemieke David H. de Southern, Jong, Luzhou Mathew Xing, Loesch Ali and Saint Louis, MO. Nirschl, Ervin Epstein and Niroshana Anandasabapathy. Boston, MA and Jabbari,Jeffrey ZhenpengB. Travers. Dai,Indianapolis, Vera H Price, IN. Madeleine Duvic, David Norris, 167 Validating the burden of disease in atopic eczema (BODE) tool as an Oakland, CA. 155* MariaEpidermal Hordinsky, differentiation Julian Mackay-Wiggan, protects against Raphael Hedgehog Clynes and pathway- Angela instrument for measuring patient-reported quality of life in atopic 005 An ex vivo skin model that combines topical skin penetration and Th17 Christiano.driven tumorigenesis. New York, MNY; GrachtchoukSan Francisco,, KL CA; Harms, Houston, A Ermilov, TX; Denver, K Pais, CO A and dermatitis. Annie Wang, Julia Ding and Abrar A. Qureshi. Providence, RI. stimulation. Mary Bedard, Steven Cook, Leandro Santos, Jessica Neil, Minneapolis,Photenhauer, MN. D Wilbert, D Metzger, P Chambon and Andrzej Dlugosz. Ann 168 Oral sirolimus improves tuberous sclerosis complex skin tumors without Carlos Eduardo Peredo, Susan H Smith, Javier Cote-Sierra and Jon Lenn. 020 CalcitoninArbor, MI andgene-related Illkirch, France. peptide (CGRP) induces endothelial cells (EC) to evidence of resistance. Neera Nathan, Ji-an Wang, Shaowei Li, Edward Research Triangle Park, NC. 156 biasEpigenomic Langerhans dysregulation cell (LC) antigen leads topresentation the aberrant towardsexpression a Th17 program response West Cowen, Mary Haughey, Joel Moss and Thomas N Darling. Bethesda, throughof cellular induction senescence of soluble . Brian Cmediators. Capell, Adam Wanhong Drake, Ding Greg, Lori Donahue, L Stohl, MD. 006 Immunomodulatory effects of AM1030, a topical 5-HT2B receptor antagonist in development for atopic dermatitis. Niklas Palmqvist, Max JohnJean ADorsey, Wagner, Parisha Linghui P Shah, Xu and Zhixun Richard Dou, David Jiajun Granstein. Zhu, Jeffery New Pawlikowski,York, NY. 169 Dupilumab suppression of Th2 biomarkers correlates with reduction in Siller, Anders Sjödin, Helena Arozenius, Christina Wenglén, Anna-Carin 021* ElevatedTaranjit Singh thymic Rai, stromal Christopher lymphopoietin Natale, Todd expression William Ridky,in the Peter skin Dblocks Adams transepidermal water loss (TEWL) and clinical improvements in adults Ryde, Lars Pettersson, Cecilia Klint, Anna Pramhed, Anna Löfdahl and breastand Shelley carcinogenesis. L Berger. Philadelphia, Shadmehr Demehri PA and Glasgow,, Trevor J UnitedCunningham, Kingdom. Sindhu with moderate-to-severe atopic dermatitis (AD). Jennifer Hamilton, Gunilla Ekström. Lund, Sweden. 157 Manivasagam,Srcasm null mice Melissa develop Meyer, UV-induced David Denardo, precancerous Raphael lesions. Kopan Johnand Wayne Sara Hamon, Usman Chaudhry, Eric L Simpson, Brian Swanson, Ming 007 Phenotypic analysis of dendritic cells infiltrating a spontaneous model Yokoyama.Seykora, X St.Yang, Louis, S Shankar, MO and K Cincinnati,Tsukamoto, MichaelOH. Gober, C Marshall, L Liu, Haobo Ren, Neil Graham, Gianluca Pirozzi and Marius Ardeleanu. of basal cell carcinoma. Christopher Nirschl, Yong Liu, Pinru Wu, Karyn 022 TopicalWang and application T Dentchev. of Philadelphia,eupatilin ameliorates PA. atopic dermatitis-like skin Tarrytown, NY; Portland, OR; Bridgewater, NJ and Basking Ridge, NJ. Haitz and Niroshana Anandasabapathy. Boston, MA. lesions of NC/Nga mice. Young Min Park, Ji Hyun Lee, Ye Jin Lee and Jun 170 Time-resolved laser induced fluorescence spectroscopy for the diagnosis 008 Potential mechanisms for loss of hair follicle immune privilege in young Lee. Seoul, Korea (the Republic of). of oral lichen planus. Parastoo Davari, Dimitris Gorpas, Julien Bec, + patients with alopecia areata following hepatitis B vaccination. 023 CD8αα T cells contribute to lichen planus independence of LAMP1- Dinglong Ma, Gregory Farwell, Laura Marcu and Nasim Fazel. Davis, CA Christopher Richardson, Elaine Gilmore and Brian Poligone. Rochester, NY. Clinicalmeditated Research degranulation. (Observations, Bing Li, Xiuwen Sun Pathophysiology and Gang Wang. Xi’an, & and Sacramento, CA. 009* CCL17 attenuates tumor immunity by increasing regulatory T cells and Outcomes)China. 171 Characteristics of patients with pseudocellulitis admitted to the Th2 cells while decreasing myeloid-derived suppressor cells in tumor 024All orals Immunomodulatory [designated with an effectsasterisk (*)]of nanoparticles listed below are on presentedthe contact in the hospital. Adam Raff, Qing Yu Weng, Priyanka Vedak, Daniela Kroshinsky microenvironment. Makoto Sugaya, Sohshi Morimura, Tomonori Oka, Clinical hypersensitivityResearch (Observations, response Pathophysiology in C57BL/6 hairless & Outcomes) mice. Samreen Minisymposium Jatana, and Arash Mostaghimi. Boston, MA. Hiraku Suga, Tomomitsu Miyagaki, Yuichiro Tsunemi, Yoshihide Asano, on Friday,Brian May C Palmer8, 2015, and from Lisa 2:00-5:00 A DeLouise. pm inRochester, Salon D, HiltonNY. Atlanta. Orals 172 Intravenous immunoglobulin for treatment of dermatomyositis- Yayoi Tada, Takafumi Kadono and Shinichi Sato. Tokyo, Japan. 025designated Capturing by two functional asterisks (**) conservation will be presented between during human a Plenary skin andSession. mouse Orals DC associated calcinosis. Fabrizio Galimberti, Anthony P Fernandez. 010 Distinctive downmodulation of plasmacytoid dendritic cell by vitamin designatedsystems by three for generating asterisks (***) better will bevaccines. presented Eynav during Klechevsky the Interdisciplinary. Saint Louis, Cleveland, OH. D3 analogue in its interferon-α production and chemotactic activity. Spotlight:MO. Skin Cancer Minisymposium on Friday, May 8, 2015, from 2:00 – 5:00 173* Identification of two salivary proteins associated with early-stage oral Takahiro Suzuki, Yoshiki Tokura. Hamamatsu, Japan. 026*pm in theHuman Grand skin Ballroom, is protected Hilton by Atlanta. four functionally and phenotypically chronic graft-versus-host disease. Richard Presland, Wedad Alshehri, 011** A wave of regulatory T cells into neonatal skin mediates tolerance to discrete populations of resident and recirculating memory T cells. Rei Melody Missaghi, Mark Schubert and Michele Lloid. Seattle, WA. commensal microbes . Tiffany C Scharschmidt, Kimberly S Vasquez, Hong- 158 WatanabeSun protection, Ahmed education Gehad, Chao delivered Yang, Lauraby tablet Campbell, personal Jessica computers: Emberley 174 Combined treatment with arsenic trioxide and itraconazole inhibits An Truong, Sofia V. Gearty, Mariela L Pauli, Audrey Nosbaum, Michael Teague,Effective Victor with Huang, kidney Tiago transplant R Matos, recipients Thomas S.with Kupper inadequate and Rachael health the hedgehog pathway in patients with refractory metastatic basal Otto, James J Moon, Abul K. Abbas, Michael A Fischbach and Michael Clark.literacy. Boston, June KMA. Robinson, Mary Kwasny, John Friedewald, Amishi Desai cell carcinoma: results from a pilot trial. Katherine J. Ransohoff, Mina David Rosenblum. San Francisco, CA; Bethesda, MD and Charlestown, 027 Noveland Elisa STAT3 J. Gordon. inhibitor Chicago, LLL12 significantly IL. reduces IL-17, IL-22, and IFN- Sarah Ally, Kavita Sarin, Scott Atwood, Melika Rezaee, Irene Bailey, Phillip MA. 159 gammaLiving with mRNA atopic expression dermatitis: in psoriatic Patient PBMCs. priorities Justin and G Hastingsneeds ,expressed Xiaoli in Beachy, Anne Lynn Su Chang, Anthony Oro, Dimitrios Colevas and Jean Y 012 Keratin 17 enhances the chemotaxis of neutrophils through regulating Zhang,social mediaJiayuh fora.Lin, Chenglong Korey L. Capozza Li and .Henry Salt Lake K Wong. City, UT.Columbus, OH. Tang. Stanford, CA. chemokine CXCL1 secretion in keratinocytes via PI3k/AKT/NF-κB 028*160 GILT-mediatedPhotoaging in African-Americanprocessing of a self skin: and A melanoma reliable photonumeric antigen in thymic scale 175* Throat infections can cause substantial aggravation of chronic plaque pathway. Er-Le Dang, Liang Jin, Chang-xu Han, Bing Li, Man Jiang and epithelialreveals age, cells male promotes gender, deletion and sun exposureand regulatory as contributory T cells. Karen factors. Taraszka psoriasis. Ragna Hlin Thorleifsdottir, Jenna Huld Eysteinsdottir, John H Gang Wang. Xi’an, China. HastingsAnna L. Chien, Matthew, Ji Qi, RadhikaRausch, ToddGrandhi, C. Metzger, Tamia Harris-Tryon, Michael Waterfield, Diane M JessicaKuhn, Olafsson, M I Sigurdsson, Andrew Johnston, Helgi Valdimarsson and 013* Contributions of skin resident and recirculating memory T cells to CortezMin Soo and Jang, Mark Noori S. Anderson. Kim, Sherry Phoenix, Leung, AZ Jessica and San Esandrio, Francisco, Barbara CA. Rainer, Baldur Sigurgeirsson. Uppsala, Sweden; Reykjavik, Iceland and Ann Arbor, depigmentation in vitiligo. Jillian Richmond, Mehdi Rashighi, Priti Flora Poon, Nancy Cheng, Ginette A Hinds and Sewon Kang. Baltimore, MI. Agarwal and John E Harris. Worcester, MA. MD. Notes: Notes:

79 1 6 PPosteroster P Presentationsresentations / /a abstractbstract t titlesitles

Adaptive176 Angiogenesis Immunity in lupus vulgaris& Vaccination and verrucosa cutis lesions 014192 AcneHigh-throughput vaccines targeting sequencing secretory of TCAMP cell receptors factor of (TCRs)Propionibacterium in human skin All orals [designatedof cutaneous with tuberculosis an asterisk . (*)]Jack listed Leonard below Arbiser are presented, Sulochana in Bhandarkar, the acnes.shows Chun-Ming a polyclonal Huang T cell. San response Diego, CA.to diphencyprone (DPCP). Nicholas Adaptive PadmavathyImmunity & Lanka,Vaccination Lakshmana Minisymposium Rao Lanka, Michaelon Saturday, Bonner May and 9, Jamie2015, 015* IdentifyingGulati, David Merkel Hamm, polyomavirus-specific Jamie Lynn Harden and CD4+ James and GCD8+ Krueger. T-cells New in York, from 12:30-3:30Mackelfresh. pm in Atlanta,Salon D, GAHilton and Atlanta. Karaikal, Orals India. designated by two asterisks MerkelNY and cell Seattle, carcinoma WA. patients’ tumor-infiltrating lymphocytes. Dafina (**)177* will beDecreased presented IL-21 during expression a Plenary in Session. skin and Orals blood designated contributes by tothree progression 193**Ibrani The, microbiomeJayasri G Iyer, of Natalie patients Vandeven, with atopic Natalie dermatitis Miller, Olga has Afanasiev, deficient asterisks (***)of mycosis will be fungoides. presented Miyoko during theKabasawa Interdisciplinary, Makoto Sugaya, Spotlight: Tomonori Skin Oka, Davidantimicrobial Koelle and function.Paul Nghiem. Teruaki Seattle, Nakatsuji WA., Tissa Hata, Aimee Two, Cancer MinisymposiumNaomi Takahashi, on Friday,Makiko May Kawaguchi, 8, 2015, Hirakufrom 2:00 Suga, – 5:00Tomomitsu pm in the Miyagaki, Grand 016* RegulatoryKimberly Chun,T cells Paulfacilitate Kotol, cutaneous Amina Bouslimani, wound healing. Haythem Audrey Latif, Nosbaum Alexandre, Ballroom,HIdeki Hilton Fujita,Atlanta. Yoshihide Asano, Yayoi Tada, Takafumi Kadono and Shinichi MonikaLockhart, Ettinger, Keli Artis, Hong-An Gloria Truong, David, PatriciaMariela LTaylor, Pauli, Joanne Sofia V. Strieb, Gearty, Peter Abul K. Sato. Tokyo, Japan. AbbasDorrestein, and Michael Karsten David Zengler, Rosenblum. Donald SanLeung Francisco, and Richard CA. L Gallo. San Diego, + + 001178 RON2315:History of A severe novel humansunburns biologic on different for the topicalbody sites treatment and risk of of psoriasis. skin 017 QuantificationCA; Chapel Hill, ofNC andCD69 CD103 Denver, skin CO. TRM cells in chronic atopic dermatitis. Thomascancers Gadek in women. Portola and Valley, men: CA.Two prospective cohort studies. Shaowei 194 SeoHyeongPembrolizumab KIM, Chang treatment: Ook Park, Cutaneous Jung U Shin, adverse Ji Yeon events Noh, and Shan correlation Jin, 002* BlockadeWu, Eunyoung for CD155-TIGIT Cho, Wen-Qing interaction Li, Martin is an A effectiveWeinstock therapyand Abrar for A. Heminwith Lee,disease Jungsoo progression Lee, Thomas . Igor S.Vujic Kupper, Martina and Kwang Sanlorenzo, Hoon Lee.Marin Seoul, Vujic, melanoma.Qureshi. Providence, Takashi Inozume RI. , Tomonori Yaguchi, Yutaka Kawakami and KoreaAdil (theDaud, Republic Alain Algazi, of) and Matthew Boston, MA.Gubens, Sara Alcantara Luna, Kevin Lin, 179 ShinjiCD4+ Shimada. histiocytosis Chuo, in Japan patients and Shinjyuku, on statins Japan. for dyslipidemia mimics early 018* SharedPietro VH1-46 Quaglino, antibody Klemens gene Rappersberger usage in pemphigus and Susana vulgaris Ortiz-Urda. predicts San 003 Migratorymycosis fungoides. DC temper Chee subcutaneous Won Oh, Carlosimmunity Torre-Cabala through keyand tolerance Madeleine antibodyFrancisco, cross-reactivity CA; Vienna, Austria to desmoglein and Turin, 3Italy. and rotavirus VP6. Michael pathways.Duvic. Houston, Niroshana TX. Anandasabapathy, Christopher Nirschl, Yong Liu, 195 JeffreySkin histopathology Tejada Cho, Christoph from patients Ellebrecht, with Christoph X-linked Matthias recessive Hammers,ichthyosis 180* ShamimEmollient Mollah, therapy Rachel alters E. Feder,skin barrier Pinru Wu,and microbesPeter Sage in and infants Arlene at Hrisk for Gopaland Sapparapu,autosomal recessiveJames Crowe congenital and Aimee ichthyosis S Payne. with Philadelphia, transglutaminase PA and Sharpe.developing Boston, atopic MA dermatitis.and New York, Heidi NY. H Kong, Martin Glatz, Eric C Polley Nashville,1 mutation. TN. Catherine Yang, Hyemin Pomerantz, Jessica Corwin, Martin 004 Rationaleand Eric L andSimpson. design Bethesda, of a novel MD dendritic and Portland, cell targeted OR. vaccine for basal 019* NextA Weinstock, generation Philip T cell Fleckman, receptor Johnsequencing J DiGiovanna reveals and complex Leslie Robinson-T cell 181 cellSkin carcinoma. mapping Karynfor classification Haitz, Steven ofR Barthel, morphea. YongHeidi Liu, Jacobe Christopher, Noelle Teske. dynamicsBostom. in Providence, Alopecia Areata RI; Vacaville, . Annemieke CA; Seattle, de Jong ,WA Luzhou and Bethesda, Xing, Ali MD. Nirschl,Dallas, Ervin TX. Epstein and Niroshana Anandasabapathy. Boston, MA and 196 Jabbari,Improved Zhenpeng survival Dai, among Vera HMerkel Price, Madeleinecell carcinoma Duvic, patients David Norris, with either an 182 Oakland,A 6-year CA. retrospective analysis of treatment patterns and outcomes Mariaunknown Hordinsky, primary Julian lesion Mackay-Wiggan, or viral oncoprotein Raphael antibodies. Clynes and ChristopherAngela 005 Anof ex epidermal vivo skin superficialmodel that combinesnon melanoma topical skin skin cancer penetration at an academic and Th17 Christiano.Wallace Lewis New, NatalieYork, NY; Vandeven, San Francisco, Kelly GCA; Paulson Houston, and TX; Paul Denver, Nghiem. CO and stimulation.dermatologic Mary surgery Bedard center., Steven Ben Cook, Drew Leandro, Pritesh Santos,Karia, Ariana Jessica Mora, Neil, Minneapolis,Seattle, WA. MN. CarlosChristine Eduardo Liang Peredo, and Chrys Susan Schmults. H Smith, Boston,Javier Cote-Sierra MA. and Jon Lenn. 020197 CalcitoninSpecific gene-relatedquality of life peptide questionnaires (CGRP) induces for the endothelialevaluation cellsof cosmetic (EC) to 183 ResearchNon-invasive Triangle imaging Park, NC.technologies for the delineation of basal cell biasproducts: Langerhans an essential cell (LC) antigentool. Caroline presentation Baudouin ,towards Clarence a deTh17 Belilovsky, response carcinomas. Syril Keena Que. Farmington, CT. throughNadège induction Lachmann of and soluble Bernard mediators. Chadoutaud. Wanhong Paris, Ding France;, Lori LEpernon, Stohl, 006 Immunomodulatory effects of AM1030, a topical 5-HT2B receptor 184 antagonistDisease manifestations in development in for patients atopic dermatitis. with subacute Niklas cutaneous Palmqvist lupus, Max JohnFrance A Wagner, and Toulouse, Linghui XuFrance. and Richard David Granstein. New York, NY. Siller,erythematosus Anders Sjödin, who Helena meet Arozenius,criteria for Christina systemic lupus.Wenglén, Janice Anna-Carin Tiao, 021*198 ElevatedEthnic comparisonthymic stromal study lymphopoietin to understand expression spreading in mechanism the skin blocks of Ryde,Victoria Lars Werth. Pettersson, Philadelphia, Cecilia Klint,PA. Anna Pramhed, Anna Löfdahl and breastpsoriasis. carcinogenesis. Jaehwan Kim Shadmehr, Chil-Hwan Demehri Oh, Jiehyun, Trevor Jeon, J Cunningham, Yoosang Baek, Sindhu 185 GunillaTopical Ekström. application Lund, ofSweden. RTA 408 lotion activates Nrf2 in human skin and is Manivasagam,Jaewoo Ahn, MelissaDong Joo Meyer, Kim, JoelDavid M Denardo, Corrêa da Raphael Rosa, Mayte Kopan Suarez-Farinas, and Wayne 007 Phenotypicwell-tolerated analysis by healthy of dendritic human cells volunteers. infiltrating Scott a spontaneousA Reisman, Chun-Yue model Yokoyama.Michelle St.Lowes Louis, and MO James and GCincinnati, Krueger. New OH. York, NY; Seoul, Korea (the ofI. basal Lee, Colin cell carcinoma. J Meyer, Joel Christopher Proksch and Nirschl Keith, Yong Ward. Liu, Irving, Pinru TX. Wu, Karyn 022 TopicalRepublic application of); Stony of Brook, eupatilin NY and ameliorates Bronx, NY. atopic dermatitis-like skin 186 HaitzQuality and ofNiroshana life in discoid Anandasabapathy. lupus patients. Boston, Noelle MA. Teske, Zachary E Cardon, 199***lesions Non-melanoma of NC/Nga skinmice. cancers Young Minare associatedPark, Ji Hyun with Lee, blood Ye Jin expansion Lee and Jun of DC- 008 PotentialXilong Li, Beverleymechanisms Huet-Adams for loss of and hair Benjamin follicle immune Franklin privilegeChong. Dallas, in TX. youngHIL+ myeloid-derivedLee. Seoul, Korea suppressor(the Republic cells of). (MDSC). Andrew P Word, Jin-Sung + 187 patientsThe cerebral with mechanismalopecia areata of scratching following andhepatitis its pleasurability B vaccination. in chronic 023 CD8Chung,αα T Travis cells contribute Vandergriff, to lichenDavid Bplanus Harker, independence Kiyoshi Ariizumi of LAMP1-and Ponciano D Christopheritch. Hideki Richardson Mochizuki,, ElaineAlexandru Gilmore D.P. andPapoiu, Brian Leigh Poligone. A Nattkemper, Rochester, NY. meditatedCruz. Dallas, degranulation. TX. Bing Li, Xiuwen Sun and Gang Wang. Xi’an, 009* CCL17Andrew attenuates Lin, Robert tumor Kraft, immunity Robert Coghillby increasing and Gil regulatoryYosipovitch. T cellsPhiladelphia, and 200 China.Epidermolysis bullosa acquisita (EBA) mimicking dystrophic Th2PA cellsand Winston-Salem,while decreasing NC. myeloid-derived suppressor cells in tumor 024 Immunomodulatoryepidermolysis bullosa effects (EB): ofImportance nanoparticles of interrogation on the contact of potential 188 microenvironment.VEGF-A and PlGF are Makoto involved Sugaya in progression, Sohshi Morimura, of cutaneous Tomonori T-cell Oka, hypersensitivitysplice site. Evelyn response Lilly, Keith in C57BL/6 A. Choate hairless and Mary mice. Tomayko. Samreen NewJatana Haven,, Hirakulymphoma. Suga, Tomomitsu Tomomitsu Miyagaki, Miyagaki ,Yuichiro Makoto Tsunemi, Sugaya, TomonoriYoshihide Oka,Asano, Naomi BrianCT. C Palmer and Lisa A DeLouise. Rochester, NY. YayoiTakahashi, Tada, Takafumi Makiko Kawaguchi, Kadono and Hiraku Shinichi Suga, Sato. HIdeki Tokyo, Fujita Japan. and Shinichi 025201 CapturingImproved functional survival in conservation metastatic melanomabetween ishuman associated skin and with mouse immune DC 010 DistinctiveSato. Tokyo, downmodulationJapan. of plasmacytoid dendritic cell by vitamin systemsgenes expressedfor generating at the better site of vaccines.disease. Eynav Ricardo Klechevsky Dante Lardone. Saint Louis,, Seema B 189 D3Clinical analogue and inmicrobiological its interferon- αhealing production of and chemotactic after threeactivity. MO.Plaisier, Peter A Sieling and Delphine J Lee. Santa Monica, CA. Takahirosessions Suzuki of 40%, Yoshiki urea Tokura. methyl-aminolevulinate-photodynamic Hamamatsu, Japan. 026*202 HumanThe incidence skin is protected of herpes by zoster four functionally in cutaneous andlupus phenotypically erythematosus 011** Atherapy wave of (PDT) regulatory versus T 40%cells ureainto neonatalplus placebo-PDT: skin mediates A multicenter, tolerance to discrete(CLE), dermatomyositispopulations of resident (DM), pemphigusand recirculating vulgaris memory(PV) and T cells.bullous Rei commensalrandomized, microbes controlled, . Tiffany phase C 3Scharschmidt clinical trial., Kimberly Yolanda GilaberteS Vasquez,, Pilar Hong- Watanabepemphigoid, Ahmed (BP) Gehad,. Elizabeth Chao S RobinsonYang, Laura, Aimee Campbell, Sue Payne, Jessica Lisa Emberley Pappas- AnRobres, Truong, Carmen Sofia Aspiroz,V. Gearty, Maria Mariela Pilar L Pauli,Frias, JesusAudrey Vera-Alvarez, Nosbaum, MichaelIgnacio Teague,Taffer, Victor Rui Feng, Huang, Joyce Tiago Okawa R Matos, and VictoriaThomas S.Werth. Kupper Phila, and PA. Rachael Otto,Garcia-Doval James J andMoon, Antonio Abul K.Rezusta. Abbas, Huesca,Michael Spain;A Fischbach Zaragoza, and SpainMichael and 203* Clark.Psoriasis Boston, area MA. severity index score positively associates with vascular DavidMadrid, Rosenblum. Spain. San Francisco, CA; Bethesda, MD and Charlestown, 027 Novelinflammation STAT3 inhibitor by FDGLLL12 PET/CT. significantly Haley B Naik reduces, Balaji IL-17, Natarajan, IL-22, andTaufiq IFN- 190* MA.Comparisons between ultraviolet B radiation and oral vitamin D gammaSalahuddin, mRNA Qimin expression Ng, Julia in psoriatic Doveikis, MartinPBMCs. Justin Playford, G HastingsBenjamin, Xiaoli Lockshin, Zhang, Jiayuh Lin, Chenglong Li and Henry K Wong. Columbus, OH. 012 Keratinsupplementation 17 enhances for the the chemotaxis treatment ofof neutrophilsvitamin D deficiency.through regulating Dong Joo Mariana Kaplan, Joel Gelfand and Nehal N. Mehta. Bethesda, MD; Silver 028* GILT-mediated processing of a self and melanoma antigen in thymic chemokineKim, Jaehwan CXCL1 Kim, secretion Jamie Lynn in keratinocytesHarden, Mary Sullivan-Whalen,via PI3k/AKT/NF-κ BPatricia Spring, MD and Philadelphia, PA. epithelial cells promotes deletion and regulatory T cells. Karen Taraszka pathway.Gilleaudeau, Er-Le Joel Dang M, CorrêaLiang Jin, da Chang-xu Rosa, Mayte Han, Suarez-Farinas, Bing Li, Man Jiang Jan Breslow,and 204 DERMO; An ontology for the description of dermatologic disease. John Hastings, Matthew Rausch, Todd C. Metzger, Michael Waterfield, Jessica GangJames Wang. G Krueger, Xi’an, China.Michelle Lowes and Manish Ponda. New York, NY; Stony Paul Sundberg, Hannah M Fisher, Robert Hoehndorf, Soheil S Dadras, Cortez and Mark S. Anderson. Phoenix, AZ and San Francisco, CA. 013* ContributionsBrook, NY and ofBronx, skin resident NY. and recirculating memory T cells to Lloyd E King, Georgios V Gkoutos and Paul N Schofield. Cambridge, 191 depigmentationGranuloma annulare in vitiligo. in patients Jillian Richmond with cutaneous, Mehdi Rashighi,B-cell lymphoma Priti . United Kingdom; Thuwal, Saudi Arabia; Farmington, CT; Nashville, TN; AgarwalJessica andMakanalani John E Harris. Donigan Worcester,, Joi B. Carter. MA. Boston, MA. Aberyswyth, United Kingdom and Bar Harbor, ME.

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1 7 80 PPosteroster P Presentationsresentations // aabstractbstract ttitlesitles

Adaptive Immunity & Vaccination 205014 AugmentedAcne vaccines cowhage-induced targeting secretory itch andCAMP altered factor papillary of Propionibacterium dermal 220 The change in serum concentration of S100A7 correlated to the change All orals [designated with an asterisk (*)] listed below are presented in the peptidgericacnes. Chun-Ming innervation Huang . inSan uremic Diego, pruritus. CA. Tiankai Du, Jasvinder Bhatia in PASI score during the treatment with adalimumab. Akimasa Adachi, Adaptive Immunity & Vaccination Minisymposium on Saturday, May 9, 2015, 015* andIdentifying Deon Wolpowitz. Merkel polyomavirus-specific Boston, MA. CD4+ and CD8+ T-cells in Mayumi Komine, Nobuki Maki, Masaru Karakawa, Satoru Murata and from 12:30-3:30 pm in Salon D, Hilton Atlanta. Orals designated by two asterisks 206* DetectionMerkel cell ofcarcinoma IFN-α response patients’ induced tumor-infiltrating by infiltrated plasmacytoidlymphocytes. Dafina Mamitaro Ohtsuki. Shimotsuke, Japan. (**) will be presented during a Plenary Session. Orals designated by three dendriticIbrani, Jayasri cells G and Iyer, keratinocytes Natalie Vandeven, via LL37 Natalie in the Miller, lesional Olga Afanasiev,skin of DIHS/ 221 Predominance of inflammatory and immune regulatory proteins in asterisks (***) will be presented during the Interdisciplinary Spotlight: Skin DRESS.David Koelle Pawinee and Rerknimitr Paul Nghiem., Saeko Seattle, Nakajima, WA. Akihiko Kitoh, Yoshiki lesional skin – Insights into hidradenitis suppurativa pathology. Matt Cancer Minisymposium on Friday, May 8, 2015, from 2:00 – 5:00 pm in the Grand 016* MiyachiRegulatory and T Kenji cells Kabashima. facilitate cutaneous Kyoto, Japan wound and healing. Bangkok, Audrey Thailand. Nosbaum, Devalaraja, Hitesh Sanganee, Sally Price, Sanna Eketjall, Chris Morehouse, Ballroom, Hilton Atlanta. 207 ImprovingMonika Ettinger, pediatric Hong-An acne management: Truong, Mariela A prospective L Pauli, Sofia multicenter V. Gearty, studyAbul K. Chris Ward, Lorraine Webber, Susanna Korolevich, Brandon Higgs, Kim ofAbbas case-based and Michael guideline David education. Rosenblum. Stephanie San Francisco, Feldstein CA., Maryam Afshar, Lehmann, Zsofia Berke and Errol Prens. Alderley Park, United Kingdom; + + 001 RON2315: A novel human biologic for the topical treatment of psoriasis. 017 AndrewQuantification Krakowski of and CD69 LawrenceCD103 skin F. Eichenfield. TRM cells in chronicSan Diego, atopic CA. dermatitis. Gaithersburg, MD and Rotterdam, Netherlands. Thomas Gadek. Portola Valley, CA. 208 CirculatingSeoHyeong KIMcentral, Chang memory Ook Park,T cells Jung might U Shin, be precursor Ji Yeon Noh, of tissueShan Jin, resident 222 Utility of T-cell receptor Vβ chain restriction and consideration for Hemin Lee, Jungsoo Lee, Thomas S. Kupper and Kwang Hoon Lee. Seoul, 002* Blockade for CD155-TIGIT interaction is an effective therapy for memory T cells (TRM) in psoriasis. Emi Nishida, Saori Kasuya, Shinnosuke changes in B1 staging in the assessment of blood involvement in CTCL. melanoma. Takashi Inozume, Tomonori Yaguchi, Yutaka Kawakami and MuramatsuKorea (the Republic and Akimichi of) and Morita. Boston, Nagoya, MA. Japan. Juliet F Gibson, Jing Huang, Kristina Liu, Kacie Carlson, Jaehyuk Choi, Shinji Shimada. Chuo, Japan and Shinjyuku, Japan. 209018* TwoShared dimensional VH1-46 antibody imaging ofgene basal usage cell in carcinoma pemphigus using vulgaris desorption predicts Richard Edelson and Michael Girardi. New Haven, CT. 003 Migratory DC temper subcutaneous immunity through key tolerance electrosprayantibody cross-reactivity ionization mass to spectrometrydesmoglein 3 (DESI-MS).and rotavirus Albert VP6. SMichael Chiou, 223 Photodynamic therapy for benign neurofibromas. Edit B Olasz, Ashley M pathways. Niroshana Anandasabapathy, Christopher Nirschl, Yong Liu, LiviaJeffrey S Eberlin, Tejada IvetteCho, Christoph Planell-Mendez, Ellebrecht, Katherine Christoph J. MatthiasRansohoff, Hammers, Jean Y Tang, Schock, Nathan Duncan, Zelmira Lazarova, Suresh Kumar, Brendan Quirk Shamim Mollah, Rachel E. Feder, Pinru Wu, Peter Sage and Arlene H SumairaGopal Sapparapu, Z Aasi and James Richard Crowe N Zare. and Stanford, Aimee S CA.Payne. Philadelphia, PA and and Harry Whelan. Milwaukee, WI. Sharpe. Boston, MA and New York, NY. 210 PhotodynamicNashville, TN. therapy using a white-light LED source is as effective and 224 Relationship of the sun protection factor and the active ingredients in 004 Rationale and design of a novel dendritic cell targeted vaccine for basal 019* well-toleratedNext generation as daylightT cell receptor photodynamic sequencing therapy reveals for complex the treatment T cell of commercial sunscreens. Manuel Gutiérrez, Elsa Arenas, Nayeli Vázquez, cell carcinoma. Karyn Haitz, Steven R Barthel, Yong Liu, Christopher actinicdynamics keratoses, in Alopecia a randomised, Areata . Annemieke single-blinded, de Jong prospective, Luzhou Xing, study. Ali Susan Benjamin Moncada, Guillermo Toriz and Javier González. San Luis Potosí, Nirschl, Ervin Epstein and Niroshana Anandasabapathy. Boston, MA and MJabbari, O’Gorman Zhenpeng, Julianne Dai, Clowry, Vera H Price,MIchael Madeleine Manley, JackieDuvic, McCavana,David Norris, Linda Mexico and Guadalajara, Mexico. Oakland, CA. Gray,Maria Ann Hordinsky, Kavanagh, Julian Aoife Mackay-Wiggan, Lally and Paul Collins.Raphael Dublin, Clynes Ireland.and Angela 225 TCR sequencing provides superior diagnosis, staging and clinical 005 An ex vivo skin model that combines topical skin penetration and Th17 211* TheChristiano. association New betweenYork, NY; aspirinSan Francisco, and NSAIDs CA; Houston,with the TX;risk Denver,of psoriasis CO and assessment of patients with cutaneous T cell lymphoma. John Thomas stimulation. Mary Bedard, Steven Cook, Leandro Santos, Jessica Neil, inMinneapolis, a population-based MN. cohort. Brandon Cohen, Kathryn J. Martires and OMalley, Ilan Kirsch, Rei Watanabe, David Williamson, Laura Campbell, Carlos Eduardo Peredo, Susan H Smith, Javier Cote-Sierra and Jon Lenn. 020 RogerCalcitonin Ho. New gene-related York, NY. peptide (CGRP) induces endothelial cells (EC) to Chris Elco, Jessica Emberley Teague, Ahmed Gehad, Elizabeth Lowry, Research Triangle Park, NC. 212 Thebias effects Langerhans of antibiotic cell (LC) antigen use on Staphylococcus presentation aureus towards carriage a Th17 rates response James G Krueger, Harlan Robins, Thomas S. Kupper and Rachael Clark. andthrough resistance induction patterns of soluble in patients mediators. with Wanhong acne vulgaris Ding ,in Lori a Ldermatology Stohl, Boston, MA; New York, NY and Seattle, WA. 006 Immunomodulatory effects of AM1030, a topical 5-HT2B receptor antagonist in development for atopic dermatitis. Niklas Palmqvist, Max setting.John A Wagner,Maria Ermenia Linghui Delost Xu and, GregoryRichard DavidRaymond Granstein. Delost, New James York, A Armile, NY. 226 Evaluation of diagnostic agreement among United States board-certified Siller, Anders Sjödin, Helena Arozenius, Christina Wenglén, Anna-Carin 021* NancyElevated Carty, thymic Christopher stromal Clymphopoietin Keller and Jenifer expression Rae Lloyd. in theYoungstown, skin blocks OH; dermatologists viewing images transmitted from Tanzania using a Ryde, Lars Pettersson, Cecilia Klint, Anna Pramhed, Anna Löfdahl and Erie,breast PA carcinogenesis. and Cleveland, OH.Shadmehr Demehri, Trevor J Cunningham, Sindhu smartphone-based store-and-forward teledermatology service. Richard Gunilla Ekström. Lund, Sweden. 213 BleachManivasagam, baths significantly Melissa Meyer, reduce David itch Denardo, and severity Raphael of atopicKopan anddermatitis Wayne David Granstein, Sarah Jane Coates. New York, NY. 007 Phenotypic analysis of dendritic cells infiltrating a spontaneous model withYokoyama. no significant St. Louis, change MO and in Cincinnati, S. aureus colonization OH. and only modest 227 Neutrophil and lymphocyte-mediated skin disease despite profound of basal cell carcinoma. Christopher Nirschl, Yong Liu, Pinru Wu, Karyn 022 effectsTopical applicationon skin barrier of function.eupatilin Nelissa ameliorates Perez-Nazario atopic ,dermatitis-like Takeshi Yoshida, skin leukopenia. Sherrie J. Divito, George A. Romar, Leigh A. Compton and Haitz and Niroshana Anandasabapathy. Boston, MA. Sadelesions Fridy, of NC/Nga Anna De mice. Benedetto Young Minand ParkLisa , AJi Beck.Hyun Rochester,Lee, Ye Jin LeeNY. and Jun Thomas S. Kupper. Boston, MA. 008 Potential mechanisms for loss of hair follicle immune privilege in 214 Doesyoung nutrition Lee. Seoul, affect Korea psoriasis (the Republic severity? of). Sarah Churton, Hope Barkoukis, 228 Validation of the Epidermolysis Bullosa Disease Activity and Scarring + patients with alopecia areata following hepatitis B vaccination. 023 SarahCD8αα Debanne, T cells contribute Thomas McCormick, to lichen planus Kevin Dindependence Cooper and Neil of LAMP1- Korman. Index: Characterising disease severity and responsiveness to clinical Christopher Richardson, Elaine Gilmore and Brian Poligone. Rochester, NY. Cleveland,meditated OH. degranulation. Bing Li, Xiuwen Sun and Gang Wang. Xi’an, change in epidermolysis bullosa. Swaranjali Vijaya Jain, Adam G Harris, 009* CCL17 attenuates tumor immunity by increasing regulatory T cells and 215 Disease–specificChina. changes in skin bacteriome and mycobiome in Atopic Clement CH Loh, Jaehwan Kim, John S Su, David Orchard, Lachlan J Th2 cells while decreasing myeloid-derived suppressor cells in tumor 024 DermatitisImmunomodulatory (AD) patients. effects Pranab of nanoparticles K Mukherjee, Jyotsnaon the contactChandra, Warren, Hamish McManus and Dedee F Murrell. Sydney, Australia; microenvironment. Makoto Sugaya, Sohshi Morimura, Tomonori Oka, Margarethypersensitivity Hammond, response Mauricio in C57BL/6Retuerto, hairless Mahmoud mice. Ghannoum Samreen Jatana and , Melbourne, Australia and Adelaide, Australia. Hiraku Suga, Tomomitsu Miyagaki, Yuichiro Tsunemi, Yoshihide Asano, SusanBrian CNedorost. Palmer and Cleveland, Lisa A DeLouise. OH. Rochester, NY. 229 A cost-effective combinational and antioxidant therapy in veteran Yayoi Tada, Takafumi Kadono and Shinichi Sato. Tokyo, Japan. 216025 SerumCapturing interleukin-6 functional levels conservation in response between to biologic human treatment skin and in patientsmouse DC psoriasis patients. Chen Ning Young, Gregory Messenger, Chelsea 010 Distinctive downmodulation of plasmacytoid dendritic cell by vitamin withsystems psoriasis. for generating Shinnosuke better Muramatsu vaccines., EmiEynav Nishida, Klechevsky Ryoji. Kubo,Saint Louis,Yoichi Duggan, Tazeen Abbas, Wasim Nasir, Christofer Hatzis and Leonard Savoy. D3 analogue in its interferon-α production and chemotactic activity. ShintaniMO. and Akimichi Morita. Nagoya, Japan. Detroit, MI. Takahiro Suzuki, Yoshiki Tokura. Hamamatsu, Japan. 217026* BeneficialHuman skin effects is protected of blood by fourgroup functionally antigen synthesis-increasing and phenotypically molecules 230 Laboratory work up for primary thrombophilia should be extensive. 011** A wave of regulatory T cells into neonatal skin mediates tolerance to ondiscrete skin moisture populations and recoveryof resident of transepidermaland recirculating water memory loss .T Sung cells. Rei Soo Benjamin Moncada, Guillermo J Ruiz-Arguelles, Camilo Martinez and Elsa commensal microbes . Tiffany C Scharschmidt, Kimberly S Vasquez, Hong- KimWatanabe, Seon-PIL, Ahmed Jin, Jang-Hee Gehad, ChaoOh, Min Yang, Kyeong Laura Shin, Campbell, Se-Rah Jessica Lee, Dong Emberley Hun Arenas. Puebla, Mexico and San Luis Potosi, Mexico. An Truong, Sofia V. Gearty, Mariela L Pauli, Audrey Nosbaum, Michael Lee,Teague, Mira Victor Choi, Huang,Soyun ChoTiago and R Matos,Jin-Ho Chung.Thomas Seoul, S. Kupper Korea and (the Rachael Republic 231 Chronologic aging in African-American skin: A reliable photonumeric Otto, James J Moon, Abul K. Abbas, Michael A Fischbach and Michael of).Clark. Boston, MA. scale reveals age and body mass index as contributory factors. Tamia David Rosenblum. San Francisco, CA; Bethesda, MD and Charlestown, 218027 Anti-desmocollinNovel STAT3 inhibitor IgG LLL12reactivity significantly appears reducesearly in IL-17,pemphigus IL-22, vulgarisand IFN- and Harris-Tryon, Anna L. Chien, Ji Qi, Radhika Grandhi, Diane M Kuhn, Min MA. isgamma associated mRNA with expression milder disease. in psoriatic S Geller PBMCs., T Schmidt, Justin RG Eming,Hastings T, XiaoliZeeli, O Soo Jang, Noori Kim, Omolara Olowoyeye, Sherry Leung, Jessica Esandrio, 012 Keratin 17 enhances the chemotaxis of neutrophils through regulating Sarig,Zhang, M Jiayuh Hertl andLin, ChenglongEli Sprecher. Li Teland Aviv, Henry Israel K Wong. and Marburg, Columbus, Germany. OH. Barbara Rainer, Flora Poon, Nancy Cheng, Ginette A Hinds and Sewon chemokine CXCL1 secretion in keratinocytes via PI3k/AKT/NF-κB 219**028* CharacterizationGILT-mediated processing of lipoprotein of a self composition and melanoma and antigenfunction in in thymic pediatric Kang. Baltimore, MD. pathway. Er-Le Dang, Liang Jin, Chang-xu Han, Bing Li, Man Jiang and psoriasisepithelial reveals cells promotes a more atherogenic deletion and profile. regulatory Wynnis T cells.Tom Karen, Lawrence Taraszka F. 232 Identifying risk factors for digital ulcers in patients with systemic Gang Wang. Xi’an, China. Eichenfield,Hastings, Matthew Martin Rausch,Playford, Todd Shehla C. Metzger,Admani, MichaelBalaji NatarajanWaterfield, and Jessica Nehal sclerosis: A retrospective, case-control study in a tertiary care academic 013* Contributions of skin resident and recirculating memory T cells to N.Cortez Mehta. and San Mark Diego, S. Anderson. CA and Bethesda, Phoenix, AZMD. and San Francisco, CA. medical center. Sarah Kam, Justin Besen, Christina Lam and Michael depigmentation in vitiligo. Jillian Richmond, Mehdi Rashighi, Priti Lichtman. Boston, MA. Agarwal and John E Harris. Worcester, MA.

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81 1 8 PPosteroster P Presentationsresentations / /a abstractbstract t titlesitles

Adaptive233 The utility Immunity of laser thermometry & Vaccination in the evaluation of plaque psoriasis. 014249 AcneThermal vaccines transport targeting characteristics secretory CAMP of human factor skin of Propionibacteriummeasured in vivo using All orals [designatedVanessa Pascoe with, anJessica asterisk Makanalani (*)] listed Donigan below are and presented Alexa B. Kimball. in the acnes.ultrathin Chun-Ming conformal Huang arrays. San of Diego, thermal CA. sensors and actuators. R. Chad AdaptiveBoston, Immunity MA. & Vaccination Minisymposium on Saturday, May 9, 2015, 015* IdentifyingWebb, Rafal Merkel Pielak, polyomavirus-specific Philippe Bastien, juha CD4+Nittynen, and CD8+Jonas T-cells Kurniawan, in from234 12:30-3:30Geographically pm in Salon adjusted D, Hilton tool Atlanta. to estimate Orals self-reporteddesignated by cumulative two asterisks MerkelMegan cell Manco, carcinoma Athena patients’ Lin, Nam tumor-infiltrating Heon Cho, Viktor Malyrchuk, lymphocytes. Guive Dafina (**) will beultraviolet presented exposure during a and Plenary associated Session. skin Orals cancer designated risk. Inbar by three Raber , Gefei IbraniBalooch, Jayasri and G John Iyer, Rogers. Natalie Urbana,Vandeven, IL; NatalieSan Francisco, Miller, OlgaCA; Aulnay Afanasiev, sous Bois, asterisks (***)Zhu, Shufengwill be presented Li, Sukolsak during Sakshuwong, the Interdisciplinary Angela Li, Caroline Spotlight: Z Tan Skin and Anne DavidFrance; Koelle Tampere, and Paul Finland Nghiem. and Seattle, Clark, NJ. WA. Cancer MinisymposiumLynn Su Chang. on Redwood Friday, May City, 8, CA. 2015, from 2:00 – 5:00 pm in the Grand 016*250 RegulatoryLikelihood T ofcells undergoing facilitate cutaneousroutine skin wound checks healing. and use Audrey of skin Nosbaum cancer , Ballroom,235 Clinical Hilton Atlanta.characteristics, disease associations, and treatment of subacute Monikainformation Ettinger, are influencedHong-An Truong, by family Mariela history L Pauli, of skinSofia cancer V. Gearty, but notAbul other K. cutaneous lupus erythematosus. Albert Gutierrez, David A. Wetter. Abbasrisk factors and Michael for skin David cancer. Rosenblum. Diane M San Kuhn Francisco,, Sabrina CA.Alessi Cesar, Radhika + + 001 RON2315:Scottsdale, A novelAZ and human Rochester, biologic MN. for the topical treatment of psoriasis. 017 QuantificationGrandhi, Timothy of Wang, CD69 CD103 Sewon skin Kang TRM and cells Anna in chronic L. Chien. atopic Baltimore, dermatitis. MD. 236 ThomasThe efficacy Gadek. Portolaof Valley, CA. for treatment of chronic pruritus: A pilot trial. 251 SeoHyeongNovel imaging KIM, Changtechniques Ook Park, for quantifying Jung U Shin, cutaneous Ji Yeon Noh, sclerosis. Shan Jin, Adela 002* BlockadeMamta Jhaveri for CD155-TIGIT, Suephy C. interaction Chen. Atlanta, is an GA. effective therapy for HeminCardones Lee, ,Jungsoo Seung Yun Lee, Lee, Thomas Joanna S. Hooten,Kupper and Lionel Kwang Banez, Hoon Ashwin Lee. Seoul,Agarwal, 237* melanoma.Characterizing Takashi subsequent Inozume ,malignancies Tomonori Yaguchi, after Yutakamycosis Kawakami fungoides. and KoreaRussell (the P RepublicHall, Keith of) Sullivan and Boston, and Mark MA. Palmeri. Durham, NC. ShinjiKathryn Shimada. J Martires Chuo,, Roger Japan Ho and and Shinjyuku, Jo-Ann Latkowski. Japan. New York, NY. 018*252 SharedIdentifying VH1-46 the antibody allergic genemarch usage related in pemphigusproteins in vulgarispost-adolescent predicts 003238 MigratorySubcutaneous DC temper abatacept subcutaneous in the treatment immunity of throughmoderate key to tolerance severe antibodyallergic marchcross-reactivity patients usingto desmoglein proteomic 3 analysis.and rotavirus Jung U VP6.Shin Michael, Ji Yeon pathways.alopecia areata.Niroshana Nhan Anandasabapathy M Nguyen, Julian, Christopher Mackay-Wiggan, Nirschl, Charlotte Yong Liu, Clark, JeffreyNoh, SeoHyeongTejada Cho, ChristophKIM, Shan Ellebrecht,Jin, Hemin ChristophLee, Jungsoo Matthias Lee, Chang Hammers, Ook Park, ShamimAli Jabbari, Mollah, Grace Rachel Ulerio, E. Feder,Megan Pinru Furniss, Wu, Raphael Peter Sage Clynes and and Arlene Angela H GopalHoward Sapparapu, Chu, Ju HeeJames Lee Crowe and Kwang and Aimee Hoon S Lee. Payne. Seoul, Philadelphia, Korea (the PA Republic and Sharpe.Christiano. Boston, New MA York, and NewNY. York, NY. Nashville,of). TN. 004239 RationaleTreatment and of angiolymphoiddesign of a novel hyperplasia dendritic withcell targeted eosinophilia: vaccine A systematicfor basal 019*253 NextThe generation percentage Tof cell dermal receptor elastin sequencing protein revealscorrelates complex with ageT cell and cellreview. carcinoma. Brandon Karyn Adler Haitz, Aimee, Steven Krausz, R Barthel, Jonathan Yong Silverberg Liu, Christopher and Hadar Lev- dynamicsFitzpatrick in Alopeciaskin type Areata rather .than Annemieke skin elasticity. de Jong Tiffany, Luzhou C.Xing, Florence Ali , Hanh Nirschl,Tov. Bronx, Ervin NY Epstein and Chicago, and Niroshana IL. Anandasabapathy. Boston, MA and Jabbari,Pham, ZhenpengBarry Reece, Dai, David Vera Gan,H Price, Geetha Madeleine Kalahasti Duvic, and David Michelle Norris, D Hines. 240 Oakland,Patients CA. with sorafenib induced drug eruptions can be successfully re- MariaDallas, Hordinsky, TX and Irving, Julian TX.Mackay-Wiggan, Raphael Clynes and Angela 005 Anchallenged. ex vivo skin Dominique model that Pichard combines, Adela topical Cardones, skin penetration Emily Chu and and Heidi Th17 H 254 Christiano.Disruption New and York, disorganization NY; San Francisco, of type CA; I collagenHouston, fibrilsTX; Denver, in early CO striaeand stimulation.Kong. Bethesda, Mary MD;Bedard Durham,, Steven NC Cook, and Philadelphia,Leandro Santos, PA. Jessica Neil, Minneapolis,gravidarum. MN. Frank Wang, Ken Calderone, Timothy RB Johnson, Gary J 241 CarlosBlood Eduardo levels of Peredo, neuron Susan specific H Smith, enolase, Javier chromogranin Cote-Sierra and A, andJon Lenn.circulating 020 CalcitoninFisher and gene-related John J Voorhees. peptide Ann (CGRP) Arbor, induces MI. endothelial cells (EC) to Researchtumor cells Triangle as Merkel Park, NC.cell carcinoma biomarkers. Isaac Brownell, Maria R 255 biasEpicutaneous Langerhans sensitization cell (LC) antigen to presentationpeanuts and other towards food a allergensTh17 response by patch Gaiser and Kenneth Daily. Bethesda, MD and Heidelberg, Germany. throughtesting induction promotes ofTh2 soluble polarization mediators. with Wanhong increased Ding IL-33., Lori Benjamin L Stohl, Ungar, 006 Immunomodulatory effects of AM1030, a topical 5-HT2B receptor 242 antagonistProgressive in necrobiosisdevelopment lipoidica for atopic of thedermatitis. bilateral Niklas breasts Palmqvist successfully, Max JohnTali A Czarnowicki, Wagner, Linghui Joel MXu Corrêa and Richard da Rosa, David James Granstein. G Krueger New and York, Emma NY. Siller,treated Anders with Sjödin, systemic Helena corticosteroids, Arozenius, Christina methotrexate, Wenglén, and Anna-Carin pentoxifylline. 021* ElevatedGuttman-Yassky. thymic stromal New York,lymphopoietin NY. expression in the skin blocks Ryde,Mital Lars Patel Pettersson,, Natalie Ann Cecilia Wright, Klint, Daniel Anna R Pramhed,Mazori, Vinod Anna EaswaranLöfdahl and 256 breastDetection carcinogenesis. of the Merkel Shadmehr cell polyomavirus Demehri, Trevor in human J Cunningham, Merkel cell Sindhu GunillaNambudiri, Ekström. Alisa Lund, Nicole Sweden. Femia and Ruth Ann Vleugels. Boston, MA and Manivasagam,carcinomas and Melissa the clinicalMeyer, implicationsDavid Denardo, of Raphaeltumor viral Kopan status. and Ryan Wayne 007 PhenotypicNew York, analysisNY. of dendritic cells infiltrating a spontaneous model Yokoyama.Doumani ,St. Ata Louis, S Moshiri, MO and Lola Cincinnati, Yelistratova, OH. Oliver Chang, Martha Delaney, 243 ofShould basal cellgranuloma carcinoma. faciale Christopher and erythema Nirschl elevatum, Yong Liu, diutinum Pinru Wu, Karynbe 022 TopicalMeei-Li application Huang, Susan of eupatilin McArdle, Paulameliorates Nghiem atopic and Astrid dermatitis-like Blom. Seattle, skin Haitzclassified and Niroshana in the IgG4-related Anandasabapathy. disease Boston,spectrum? MA. Histopathologic and lesionsWA. of NC/Nga mice. Young Min Park, Ji Hyun Lee, Ye Jin Lee and Jun 008 Potentialimmunophenotypic mechanisms appraisal for loss of 32hair cases. follicle Sima immune Kavand privilege, Julia Lehman in 257 youngUnique Lee. cutaneous Seoul, Korea reaction (the Republic to second- of). and third-generation tyrosine + patientsand Lawrence with alopecia Gibson. Evanston,areata following IL and Rochester,hepatitis MN.B vaccination. 023 CD8kinaseαα T inhibitors cells contribute for chronic to lichen myeloid planus leukemia. independence Anisha Patelof LAMP1-, Alvin 244* ChristopherAssessment Richardson of the genetic, Elaine basis Gilmore of rosacea and Brian by Poligone.genome-wide Rochester, association NY. meditatedSolomon, degranulation. Michael Mauro Bing and Li Benjamin, Xiuwen SunD Ehst. and Houston, Gang Wang. TX; Portland,Xi’an, OR 009* CCL17study. attenuates Anne Lynn tumorSu Chang immunity, Inbar Raber, by increasing Jin Xu, Rui regulatory Li, Robert T Spitale,cells and Julia China.and New York, NY. Th2Chen, cells Amy while Kiefer, decreasing Chao Tian, myeloid-derived Nicholas Eriksson, suppressor David Hinds cells in and tumor Joyce 024258 ImmunomodulatoryUstekinumab treatment effects of ofpsoriatics nanoparticles infected on withthe contacthepatitis B and/or microenvironment.Tung. Redwood City, Makoto CA; Irvine, Sugaya CA, andSohshi Mountainview, Morimura, Tomonori CA. Oka, hypersensitivityhepatitis C virus. response Benjamin in DC57BL/6 Ehst, Sarah hairless Siegel, mice. Scott Samreen Naugler Jatana and, Kevin 245 HirakuCharacteristics Suga, Tomomitsu of ocular Miyagaki, melanoma Yuichiro at University Tsunemi, YoshihideHospitals Asano,Case Medical BrianWinthrop. C Palmer Portland, and Lisa OR. A DeLouise. Rochester, NY. YayoiCenter: Tada, 1996-2013. Takafumi KadonoRitva Vyas and, Erica Shinichi Gotow, Sato. Adam Tokyo, Gerstenblith, Japan. Kord 025259 CapturingClinical features functional of PRPconservation from patient between and provider human perspectives:skin and mouse An DC 010 DistinctiveHonda, Kevin downmodulation D Cooper and Meg of Rebeccaplasmacytoid Gerstenblith. dendritic Hagerstown, cell by vitamin MD; systemsepidemiologic for generating cross-sectional better vaccines.study Eynavof 100 KlechevskyPRP cases. Nicholas. Saint Louis, A Ross , D3Cleveland analogue Heights, in its interferon- OH and Cleveland,α production OH. and chemotactic activity. MO.Hye Jin Chung, Matthew S Keller, J. Andrews, Q. Li and Jouni Uitto. 246 TakahiroQuality Suzukiof life, is Yoshiki equivalent Tokura. between Hamamatsu, atopic Japan. dermatitis patients managed 026* HumanPhiladelphia, skin is protected PA. by four functionally and phenotypically 011** Athrough wave of aregulatory direct-access T cells online into modelneonatal compared skin mediates to in-office tolerance care: to A 260 discreteHashimoto’s populations thyroiditis of resident associated and recirculatingwith psoriasis: memoryA cross-sectional T cells. Rei commensalrandomized microbes controlled . Tiffany trial. April C Scharschmidt W. Armstrong, Kimberly, Mary SAnn Vasquez, Johnson, Hong- Watanabestudy . Alba, Ahmed Posligua Gehad,, Tinatin Chao Yang,Kiguradze, Laura Finola Campbell, Bruins, Jessica Tanya Emberley AnSteven Truong, Lin, Sofia Caitlin V. Clark,Gearty, Aleksandra Mariela L G.Pauli, Florek Audrey and Fu-TongNosbaum, Liu. Michael Aurora, CO Teague,Bhattacharya, Victor Huang, Alfred Tiago Rademaker, R Matos, Ahmad Thomas S S.Amin, Kupper Anne and Elizabeth Rachael Otto,and Sacramento,James J Moon, CA. Abul K. Abbas, Michael A Fischbach and Michael Clark.Laumann, Boston, Steven MA. M Belknap, Dennis P West and Beatrice Nardone. 247 DavidUltraviolet Rosenblum. light (UVB)San Francisco, alteration CA; of Bethesda, epidermal MD nerve and Charlestown,fibers (ENFs) and 027 NovelChicago, STAT3 IL. inhibitor LLL12 significantly reduces IL-17, IL-22, and IFN- MA.neuropeptides: A possible mechanism for the efficacy of light therapy 261 gammaForward-looking mRNA expression infrared in imaging psoriatic predicts PBMCs. ultimate Justin G burnHastings depth, Xiaoli in a 012 Keratinin pruritic 17 enhancespatients. Aaronthe chemotaxis Tyler Follansbee of neutrophils, Ioanna G.through Panoutsopoulou, regulating Zhang,porcine Jiayuh vertical Lin, Chenglong injury progression Li and Henry model. K Wong. Joseph Columbus, Anthony MiccioOH. , Shruti chemokineGwen Wendelschafer-Crabb, CXCL1 secretion in William keratinocytes R. Kennedy, via PI3k/AKT/NF-Elisabeth Hurliman,κB 028* GILT-mediatedParikh, Xavier processing Marinaro, ofAtulya a self Prasad, and melanoma Cheng Qian, antigen Steven in McClain, thymic pathway.Maria Hordinsky, Er-Le Dang George, Liang L. Jin, Wilcox Chang-xu and ElhabibHan, Bing Benlhabib. Li, Man Jiang Minneapolis, and epithelialAdam Singer cells promotesand Richard deletion August Clark.and regulatory Stony Brook, T cells. NY Karenand Ithaca, Taraszka NY. GangMN. Wang. Xi’an, China. 262 HastingsHost T ,cells Matthew survive Rausch, conditioning Todd C. inMetzger, skin and Michael are present Waterfield, during Jessicaacute 013*248 ContributionsTRAF3IP2 D10N of limitsskin resident IL-17-induced and recirculating expression of memory TNFAIP3 T cells and toNFKBIZ CortezGVHD. and Sherrie Mark J.S. DivitoAnderson., Chris Phoenix, Elco, Thomas AZ and S. San Kupper Francisco, and Zihao CA. Yan. depigmentationin psoriasis: Regulating in vitiligo. the Jillian regulators? Richmond Sylviane, Mehdi Lambert Rashighi,, Stefan Priti W Stoll, Boston, MA. AgarwalLam C. andTsoi, John Rajan E PHarris. Nair andWorcester, James T MA. Elder. Ann Arbor, MI.

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1 9 82 PPosteroster P Presentationsresentations // aabstractbstract ttitlesitles

Adaptive Immunity & Vaccination 263*014 SharedAcne vaccines inflammatory targeting signatures secretory between CAMP factor atherosclerotic of Propionibacterium plaques 278 Myeloid biomarkers and vascular PET-MRI during psoriasis treatments: All orals [designated with an asterisk (*)] listed below are presented in the andacnes. psoriasis Chun-Ming skin. HuangJohann. SanEli Gudjonsson Diego, CA. , William R Swindell, Andrew Preliminary report. Thomas McCormick, Jackelyn B Golden, Scott Santilli, Adaptive Immunity & Vaccination Minisymposium on Saturday, May 9, 2015, 015* Johnston,Identifying Santhi Merkel Ganesh, polyomavirus-specific Katherine Gallagher, CD4+ Nicole and L Ward,CD8+ T-cells Xianying in Fuad Muakkassa, Prabhakar Rajiah, James K O’Donnell, Sarah G Groft, from 12:30-3:30 pm in Salon D, Hilton Atlanta. Orals designated by two asterisks Xing,Merkel Mrinal cell carcinomaKumar Sarkar, patients’ Rajan Ptumor-infiltrating Nair and James T Elder. lymphocytes. Ann Arbor, Dafina MI Fabrizio Galimberti, David C Soler, Neil Korman and Kevin D Cooper. (**) will be presented during a Plenary Session. Orals designated by three andIbrani Cleveland,, Jayasri G OH. Iyer, Natalie Vandeven, Natalie Miller, Olga Afanasiev, Cleveland, OH. asterisks (***) will be presented during the Interdisciplinary Spotlight: Skin 264 CharacterizationDavid Koelle and Paulof gene Nghiem. expression Seattle, biomarker WA. signatures in cross- 279 Adult-onset linear morphea is associated with significant morbidity Cancer Minisymposium on Friday, May 8, 2015, from 2:00 – 5:00 pm in the Grand 016* sectionalRegulatory and T cells longitudinal facilitate studiescutaneous for wounduse as anhealing. Alopecia Audrey Areata Nosbaum Disease, and methotrexate may reduce risk of disease reactivation. Natalie Ann Ballroom, Hilton Atlanta. ActivityMonika Ettinger,Index (ALADIN). Hong-An Jane Truong, E Cerise Mariela, Ali Jabbari, L Pauli, Madeleine Sofia V. Gearty,Duvic, Abul K. Wright, Daniel R Mazori, Mital Patel, Sarika Ramachandran, Andrew G MariaAbbas Hordinsky, and Michael David David Norris, Rosenblum. Vera H Price,San Francisco, Julian Mackay-Wiggan, CA. Franks, Ruth Ann Vleugels and Alisa Nicole Femia. New York, NY and + + 001 RON2315: A novel human biologic for the topical treatment of psoriasis. 017 RaphaelQuantification Clynes and of Angela CD69 CD103 Christiano. skin TRM Newcells York,in chronic NY; Houston, atopic dermatitis. TX; Boston, MA. Thomas Gadek. Portola Valley, CA. Minneapolis,SeoHyeong KIM MN;, Chang Denver, Ook CO Park, and JungSan Francisco, U Shin, Ji YeonCA. Noh, Shan Jin, 280 An integrated model of atopic dermatitis (AD) severity based on 002* Blockade for CD155-TIGIT interaction is an effective therapy for 265 HyaluronanHemin Lee, Jungsoosynthase Lee, 2 antisense Thomas S. transcript Kupper and level Kwang associates Hoon Lee.with Seoul, human lesional, non lesional and systemic biomarkers. Mayte Suarez-Farinas, melanoma. Takashi Inozume, Tomonori Yaguchi, Yutaka Kawakami and skinKorea youthfulness (the Republic as of) identified and Boston, by MA.transcriptome sequencing. Jin Xu, James G Krueger, Sandra Garcet, Shinji Noda and Emma Guttman-Yassky. Shinji Shimada. Chuo, Japan and Shinjyuku, Japan. 018* RyanShared A Flynn, VH1-46 Robert antibody Spitale, gene Eduardo usage inTorre, pemphigus Rui Li, Dale vulgaris G Kern, predicts Helen New York, NY. 003 Migratory DC temper subcutaneous immunity through key tolerance Knaggs,antibody Howard cross-reactivity Chang and Anneto desmoglein Lynn Su Chang. 3 and Stanford,rotavirus CA;VP6. Michael Irvine, CA 281 Approaching zero— long-term blockade of IL-17RA with brodalumab pathways. Niroshana Anandasabapathy, Christopher Nirschl, Yong Liu, andJeffrey Provo, Tejada UT. Cho, Christoph Ellebrecht, Christoph Matthias Hammers, substantially abates psoriasis “residual disease expression” signature. Shamim Mollah, Rachel E. Feder, Pinru Wu, Peter Sage and Arlene H 266 AberrantGopal Sapparapu, fibroblast James differentiation Crowe and Aimee towards S Payne. cartilage Philadelphia, and bone PA and underlies Chris B Russell, Jeannette Bigler, Keith Kerkof, Judilyn Fuentes Duculan, Sharpe. Boston, MA and New York, NY. humanNashville, keloids. TN. Judilyn B Fuentes-Duculan, Kathleen M Bonifacio, Xuguang Hu, Timour Marty, Michael Boedigheimer, Abraham Anderson, 004 Rationale and design of a novel dendritic cell targeted vaccine for basal 019* MichaelNext generation H Tirgan, MayteT cell receptor Suarez-Farinas sequencing and Jamesreveals G complexKrueger. NewT cell York, Greg Kricorian, Paul Klekotka, Ajay Nirula and James G Krueger. Seattle, cell carcinoma. Karyn Haitz, Steven R Barthel, Yong Liu, Christopher NY.dynamics in Alopecia Areata . Annemieke de Jong, Luzhou Xing, Ali WA; Thousand Oaks, CA and New York, NY. Nirschl, Ervin Epstein and Niroshana Anandasabapathy. Boston, MA and 267 TheJabbari, impact Zhenpeng of chocolate Dai, Vera consumption H Price, Madeleine on acne Duvic,vulgaris David . Jenifer Norris, Rae 282 Using RNA-seq in the transcriptome analysis of the Koebner Oakland, CA. LloydMaria, GregoryHordinsky, Raymond Julian Mackay-Wiggan, Delost, Jacqueline Raphael Selph, Clynes Maria andErmenia Angela Delost phenomenon in psoriasis. Kimberly Chun, Stella Chen, Aimee Two, Tissa 005 An ex vivo skin model that combines topical skin penetration and Th17 andChristiano. Rachael JNew Pohle-Krauza. York, NY; San Cleveland, Francisco, OH; CA; Erie, Houston, PA and TX; Youngstown, Denver, CO OH.and Hata and Richard L Gallo. La Jolla, CA. stimulation. Mary Bedard, Steven Cook, Leandro Santos, Jessica Neil, 268 GenitalMinneapolis, metastasis MN. from a primary colorectal cancer: Case report. Karla Carlos Eduardo Peredo, Susan H Smith, Javier Cote-Sierra and Jon Lenn. 020 ImeldaCalcitonin Martínez-Rosales gene-related peptide, Benjamin (CGRP) Moncada. induces San endothelial Luis Potosi, cellsMexico. (EC) to Research Triangle Park, NC. 269 Neuralbias Langerhans contribution cell (LC)to augmented antigen presentation protease-dependent towards apruritus Th17 response in through induction of soluble mediators. Wanhong Ding, Lori L Stohl, 006 Immunomodulatory effects of AM1030, a topical 5-HT2B receptor seborrheic dermatitis scalp skin. Deon Wolpowitz, Salma Goummih, Epidemiology antagonist in development for atopic dermatitis. Niklas Palmqvist, Max TiankaiJohn A Wagner,Du, Tara LinghuiConniff, Xu Avner and RichardBar-Hen, David Jessica Granstein. Langer, NewOdette York, NY. All orals [designated with an asterisk (*)] listed below are presented in the Siller, Anders Sjödin, Helena Arozenius, Christina Wenglén, Anna-Carin 021* Jammayrac,Elevated thymic Roland stromal Jourdain lymphopoietin and Lionel Breton. expression Boston, in theMA; skin Paris, blocks Epidemiology Minisymposium on Thursday, May 7, 2015, from 2:00-5:00 pm in Ryde, Lars Pettersson, Cecilia Klint, Anna Pramhed, Anna Löfdahl and France;breast carcinogenesis.Clark, NJ and Aulnay Shadmehr sous Bois,Demehri France., Trevor J Cunningham, Sindhu Salon C, Hilton Atlanta. Orals designated by two asterisks (**) will be presented Gunilla Ekström. Lund, Sweden. 270 UniversityManivasagam, tort Melissaliability Meyer,for allowing David college Denardo, debit Raphael card purchasingKopan and Wayne during a Plenary Session. Orals designated by three asterisks (***) will be 007 Phenotypic analysis of dendritic cells infiltrating a spontaneous model ofYokoyama. indoor UV St. tanning. Louis, MO Konstantin and Cincinnati, Grigoryan OH., Arthur Best and Robert presented during the Interdisciplinary Spotlight: Skin Cancer Minisymposium on of basal cell carcinoma. Christopher Nirschl, Yong Liu, Pinru Wu, Karyn 022 Dellavalle.Topical application Cincinnati, of OHeupatilin and Denver, ameliorates CO. atopic dermatitis-like skin Friday, May 8, 2015, from 2:00 – 5:00 pm in the Grand Ballroom, Hilton Atlanta. Haitz and Niroshana Anandasabapathy. Boston, MA. 271 Successfullesions of NC/Ngatreatment mice. of palmoplantarYoung Min Park pustulosis, Ji Hyun Lee, with Ye adalimumab. Jin Lee and Jun 008 Potential mechanisms for loss of hair follicle immune privilege in Rudolfyoung Lee.E. Schopf Seoul,, Erato Korea Beis. (the Mainz, Republic Germany. of). 283 Reliability and validity of outcome instruments for assessing cutaneous + patients with alopecia areata following hepatitis B vaccination. 272023 OralCD8 ααruxolitinib T cells contribute induces hair to lichenregrowth planus in independencemoderate to severe of LAMP1- alopecia sarcoidosis among dermatologists and non-dermatologists. Misha Christopher Richardson, Elaine Gilmore and Brian Poligone. Rochester, NY. areata.meditated Julian degranulation. Mackay-Wiggan Bing, Nhan Li, Xiuwen M Nguyen, Sun and Charlotte Gang Wang. Clark, Xi’an, Ali Rosenbach, Howa Yeung and Sara Farber. Atlanta, GA and Philadelphia, 009* CCL17 attenuates tumor immunity by increasing regulatory T cells and Jabbari,China. Grace Ulerio, Megan Furniss, Raphael Clynes and Angela PA. Th2 cells while decreasing myeloid-derived suppressor cells in tumor 024 Christiano.Immunomodulatory New York, effects NY. of nanoparticles on the contact 284* Disparities in sunburns, photoprotection, indoor tanning, and skin microenvironment. Makoto Sugaya, Sohshi Morimura, Tomonori Oka, 273 Ahypersensitivity meta-analysis of response laboratory in C57BL/6monitoring hairless during mice. treatment Samreen with Jatana , cancer screening among U.S. men and women in same- and opposite- Hiraku Suga, Tomomitsu Miyagaki, Yuichiro Tsunemi, Yoshihide Asano, isotretinoin.Brian C Palmer Thomas and Lisa P. ScharnitzA DeLouise., Joslyn Rochester, Kirby and NY. Young S. Lee. Hershey, sex relationships. Howa Yeung, Suephy C. Chen. Atlanta, GA. Yayoi Tada, Takafumi Kadono and Shinichi Sato. Tokyo, Japan. 025 PA.Capturing functional conservation between human skin and mouse DC 285 The early risk of an internal malignancy development in patients with systems for generating better vaccines. Eynav Klechevsky. Saint Louis, 010 Distinctive downmodulation of plasmacytoid dendritic cell by vitamin 274 Detection of PTCH1 in human vulvar basal cell carcinomas via in-situ dermatitis herpetiformis seems to be exaggerated. Marian Dmochowski, MO. D3 analogue in its interferon-α production and chemotactic activity. hybridization: Implications for targeted molecular therapy. Hoseong Justyna Gornowicz-Porowska, Pawel Pietkiewicz and Monika Bowszyc- 026* Human skin is protected by four functionally and phenotypically Takahiro Suzuki, Yoshiki Tokura. Hamamatsu, Japan. Steven Yang, Gunsik Cho, Sewon Kang and Janis Marie Taube. Baltimore, Dmochowska. Poznan, Poland. discrete populations of resident and recirculating memory T cells. Rei 011** A wave of regulatory T cells into neonatal skin mediates tolerance to MD. 286* Ozone exposure and extrinsic skin aging: Results from the SALIA cohort. Watanabe, Ahmed Gehad, Chao Yang, Laura Campbell, Jessica Emberley commensal microbes . Tiffany C Scharschmidt, Kimberly S Vasquez, Hong- 275 Atopic dermatitis in children: Relationship with phosphocalcic Jean Krutmann, Anke Hüls, Tamara Schikowski, Ursula Krämer, Dorothee Teague, Victor Huang, Tiago R Matos, Thomas S. Kupper and Rachael An Truong, Sofia V. Gearty, Mariela L Pauli, Audrey Nosbaum, Michael metabolism, weight and lipids. Yolanda Gilaberte, Pedro Agón, Rosalía Sugiri, Sabine Stolz and Andrea Vierkoetter. Düsseldorf, Germany and Clark. Boston, MA. Otto, James J Moon, Abul K. Abbas, Michael A Fischbach and Michael Sanmartín, Angela Hernández-Martin, Roberto Alijarde, Carlos Pardos, Basel, Switzerland. 027 Novel STAT3 inhibitor LLL12 significantly reduces IL-17, IL-22, and IFN- David Rosenblum. San Francisco, CA; Bethesda, MD and Charlestown, Jose Puzo and Ana J García-Malinis. Jaca, Spain; Huesca, Spain; Madrid, 287* Incidence of skin cancer in a cohort of 1278 patients with vitiligo, 2001- gamma mRNA expression in psoriatic PBMCs. Justin G Hastings, Xiaoli MA. Spain and Zaragoza, Spain. 2013. Liza Gill, Gordon Jacobsen, Richard Krajenta, Henry W. Lim, Iltefat H Zhang, Jiayuh Lin, Chenglong Li and Henry K Wong. Columbus, OH. 012 Keratin 17 enhances the chemotaxis of neutrophils through regulating 276 Underrepresented minorities (URMs) and perspectives on successful Hamzavi and Melody J. Eide. Detroit, MI and East Lansing, MI. 028* GILT-mediated processing of a self and melanoma antigen in thymic chemokine CXCL1 secretion in keratinocytes via PI3k/AKT/NF-κB matching to dermatology residency. Rebecca Vasquez, Sam Jeong and 288 Evidence that outdoor air pollutants including particulate matter (PM) epithelial cells promotes deletion and regulatory T cells. Karen Taraszka pathway. Er-Le Dang, Liang Jin, Chang-xu Han, Bing Li, Man Jiang and Amit Pandya. Dallas, TX. as well as gases influence skin aging in a Chinese population. Anke Hüls, Hastings, Matthew Rausch, Todd C. Metzger, Michael Waterfield, Jessica Gang Wang. Xi’an, China. 277 Lymphatic vessel endothelial hyaluronan receptor-1 (LYVE-1) expression Yajun Yang, Wenshan Gao, Andrea Vierkoetter, Tamara Schikowski, Anan Cortez and Mark S. Anderson. Phoenix, AZ and San Francisco, CA. 013* Contributions of skin resident and recirculating memory T cells to is similar in normal human parietal and occipital scalp. Brooke Hanson, Ding, Juan Zhang, Mary S Matsui, Haidong Kan, Li Jin, Sijia Wang and Jean depigmentation in vitiligo. Jillian Richmond, Mehdi Rashighi, Priti Melissa Weber-Sanders, James Hodges, Heather Bemmels, Maria Krutmann. Düsseldorf, Germany; Shanghai, China; Taizhou, China and Agarwal and John E Harris. Worcester, MA. Hordinsky and Marna Ericson. Minneapolis, MN. Melville, NY.

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1 83 10 PPosteroster P Presentationsresentations / /a abstractbstract t titlesitles

Adaptive289* Increased Immunity risk of pneumonia & Vaccination among patients with psoriasis: A 014303 AcneSex vaccinesand psoriasis: targeting An examination secretory CAMP of sexual factor activitiesof Propionibacterium and psychometric All orals [designatedpopulation-based with an asteriskcohort study (*)] listed in the below United are Kingdom. presented Junko in the Takeshita , acnes.properties Chun-Ming of the Huang sexual. San activity Diego, CA.questionnaire (SAQ) among female AdaptiveDaniel Immunity B Shin, & VaccinationAlexis Ogdie andMinisymposium Joel Gelfand. on Philadelphia, Saturday, May PA. 9, 2015, 015* Identifyingpsoriasis patients. Merkel polyomavirus-specificApril W. Armstrong, Aleksandra CD4+ and G. CD8+ Florek T-cells and Elizabethin from290 12:30-3:30Thyroid pm abnormalities in Salon D, Hilton are prevalent Atlanta. Oralsin primary designated Raynaud’s by two phenomenon asterisks MerkelA. Brezinski. cell carcinoma San Francisco, patients’ CA andtumor-infiltrating Aurora, CO. lymphocytes. Dafina (**) will beand presented thyroid-directed during a therapyPlenary Session.may improve Orals responsedesignated to by Raynaud’s three 304 IbraniVitiligo, Jayasri and G associated Iyer, Natalie pigmentation, Vandeven, Natalie sun Miller,exposure, Olga and Afanasiev, lifestyle factors asterisks (***)treatment. will be Daniel presented R Mazori during, Alisa the NicoleInterdisciplinary Femia. New Spotlight: York, NY. Skin Davidin women. Koelle and Newsha Paul Nghiem.Lajevardi Seattle,, Shaowei WA.Wu, Wen-Qing Li, Eunyoung Cho Cancer291* MinisymposiumLong-term efficacy on Friday, of topical May 8, 5-fluorouracil 2015, from 2:00 5% – 5:00cream pm in intreating the Grand actinic 016* Regulatoryand Abrar T A. cells Qureshi. facilitate Providence, cutaneous RI. wound healing. Audrey Nosbaum, Ballroom,keratosis. Hilton Atlanta. Hyemin Pomerantz, Daniel Hogan, David Eilers, Susan Swetter, 305* MonikaA large Ettinger, cohort study Hong-An of lithium Truong, use Marielaand melanoma L Pauli, Sofia incidence V. Gearty, and Abul K. Suephy C. Chen, Sharon Jacob, Erin M. Warshaw, George Stricklin, Robert Abbasprogression. and Michael Maryam David Mandana Rosenblum. Asgari San, ZhengFrancisco, Zhu, CA. E. Margaret Warton, + + 001 RON2315:Dellavalle, A Navjeet novel human Sidhu-Malik, biologic Nellie for the Konnikov, topical Victoriatreatment Werth, of psoriasis. Jonette 017 QuantificationCharles Quesenberry, of CD69 CD103Bruce Fireman skin TRM and cells Andy in chronic Chien. atopicOakland, dermatitis. CA and ThomasKeri, Robert Gadek Lew. Portola and Martin Valley, CA.A Weinstock. Providence, RI; Bay Pines, FL; SeoHyeongSeattle, KIMWA. , Chang Ook Park, Jung U Shin, Ji Yeon Noh, Shan Jin, 002* BlockadeHines, IL; for Palo CD155-TIGIT Alto, CA; Atlanta, interaction GA; San is anDiego, effective CA; Minneapolis, therapy for MN; 306 HeminWITHDRAWN Lee, Jungsoo Lee, Thomas S. Kupper and Kwang Hoon Lee. Seoul, melanoma.Nashville, TN;Takashi Denver, Inozume CO; Durham,, Tomonori NC; Yaguchi, Boston, Yutaka MA; Philadelphia, Kawakami and PA and 307 KoreaSustained (the Republic reduction of) andin skin Boston, biopsies MA. after 5-FU treatment. Joanna L ShinjiMiami, Shimada. FL. Chuo, Japan and Shinjyuku, Japan. 018* SharedWalker VH1-46, Moniyka antibody Sachar, geneHyemin usage Pomerantz, in pemphigus Suephy vulgaris C. Chen, predicts Susan 003292 MigratoryParotid-associated DC temper subcutaneousmelanoma of unknownimmunity primarythrough site: key tolerance antibodySwetter, cross-reactivity Robert Dellavalle, to Georgedesmoglein Stricklin 3 and and rotavirus Martin AVP6. MichaelWeinstock. pathways.Clinicopathologic Niroshana characteristics Anandasabapathy from, Christophera tertiary referralNirschl, centerYong Liu, . Jeffrey JeffreyProvidence, Tejada RI;Cho Atlanta,, Christoph GA; Ellebrecht, Palo Alto, CA;Christoph Denver, Matthias CO and Nashville,Hammers, TN. ShamimF Scott ,Mollah, Ritva Vyas, Rachel Kord E. Honda,Feder, Pinru Chad Wu,Zender, Peter Rod Sage Rezaee, and Arlene Pierre H Lavertu, 308 GopalAssessment Sapparapu, of atopic James dermatitis Crowe and Aimee using Sself- Payne. and Philadelphia,caregiver- report: PA and A Sharpe.Henry Koon,Boston, Kevin MA andD Cooper New York, and MegNY. Rebecca Gerstenblith. Cleveland, Nashville,multicenter TN. validation study. Jonathan Silverberg, Neha Patel, Supriya 004 RationaleOH. and design of a novel dendritic cell targeted vaccine for basal 019* NextImmaneni, generation Nanette T cell Breceptor Silverberg, sequencing Reja Debashis, reveals Natasha complex Fewkes T cell and Eric 293 cellPhenotyping carcinoma. of Karyn extrinsic Haitz skin, Steven aging R Barthel,of German, Yong Chinese Liu, Christopher and Japanese dynamicsL Simpson. in Alopecia Chicago, AreataIL; New . York,Annemieke NY and de Portland, Jong, Luzhou OR. Xing, Ali Nirschl,women. Ervin Andrea Epstein Vierkoetter and Niroshana, Tamara Anandasabapathy. Schikowski, Mohammad Boston, Vossoughi,MA and 309 Jabbari,Increased Zhenpeng utilization Dai, Vera of high-costH Price, Madeleine care settings Duvic, by David patients Norris, with Oakland,Sabine Stolz, CA. Anke Hüls, Mary S Matsui, Ai Yamamoto, Li Jin, Akimichi Mariahidradenitis Hordinsky, suppurativa: Julian Mackay-Wiggan, Investigation Raphael of disease-specificClynes and Angela utilization . 005 AnMorita, ex vivo Sijia skin Wang, model Zhiwen that combines Li and Jean topical Krutmann. skin penetration Nagoya, Japan; and Beijing,Th17 Christiano.Joslyn Kirby New, Amrit York, S. KhalsaNY; San andFrancisco, Guodong CA; S.Houston, Liu. Hershey, TX; Denver, PA. CO and stimulation.China; Düsseldorf, Mary Bedard Germany;, Steven Melville, Cook, NY Leandro and Shanghai, Santos, Jessica China. Neil, 310 Minneapolis,The risk of Parkinson’sMN. disease in patients with psoriasis: A population- 294 CarlosA retrospective Eduardo Peredo, analysis Susan of theH Smith, association Javier Cote-Sierra of dioxin (agent and Jon orange) Lenn. 020 Calcitoninbased cohort gene-related study. Jina peptide Chung (CGRP), Junko inducesTakeshita, endothelial Daniel B Shin, cells (EC) to Researchexposure Triangle and cutaneous Park, NC. t-cell lymphoma. Ali Dana, Ravi Vinnakota, biasKevin Langerhans Haynes, Stevencell (LC) E antigenArnold and presentation Joel Gelfand. towards Baltimore, a Th17 MD response and Yeun-Hee Park, Jessica Newman, Erik Langhoff and Larisa Geskin. Bronx, throughPhiladelphia, induction PA. of soluble mediators. Wanhong Ding, Lori L Stohl, 006 Immunomodulatory effects of AM1030, a topical 5-HT2B receptor antagonistNY and New in developmentYork, NY. for atopic dermatitis. Niklas Palmqvist, Max 311 JohnPigmentary A Wagner, traits Linghui and Xu indoor and Richard tanning David bed useGranstein. among New women York, in NY. the 295 Siller,The epidemiologyAnders Sjödin, ofHelena angiolymphoid Arozenius, hyperplasiaChristina Wenglén, with eosinophilia Anna-Carin – A 021* ElevatedUnited thymicStates. stromalWen-Qing lymphopoietin Li, Eunyoung Cho,expression Shaowei in Wuthe andskin Abrarblocks A. Ryde,systematic Lars Pettersson, review. Hadar Cecilia Lev-Tov Klint,, AimeeAnna Pramhed, Krausz, Brandon Anna Löfdahl Adler and breastQureshi. carcinogenesis. Providence, ShadmehrRI. Demehri, Trevor J Cunningham, Sindhu GunillaJonathan Ekström. Silverberg. Lund, Bronx, Sweden. NY and Chicago, IL. 312 Manivasagam,Misinformation Melissa is prevalent Meyer, David in psoriasis-related Denardo, Raphael YouTube Kopan videos.and Wayne Ji 007296* PhenotypicDuration analysisof oral antibiotic of dendritic therapy cells infiltrating for the treatment a spontaneous of adult model Yokoyama.Qi, Sarah St.Joo, Louis, Trinh MO Trang, and Judy Cincinnati, Doong, SewonOH. Kang and Anna L. Chien. ofacne: basal A cell retrospective carcinoma. Christopheranalysis investigating Nirschl, Yong adherenceLiu, Pinru Wu,to guideline Karyn 022 TopicalBaltimore, application MD. of eupatilin ameliorates atopic dermatitis-like skin Haitzrecommendations and Niroshana Anandasabapathy. and opportunities Boston, for cost-savings. MA. Joslyn Kirby, 313 lesionsBradford of NC/Nga hill criteria mice. support Young Minthe surgeonPark, Ji Hyun general Lee, stating Ye Jin Lee that and indoor Jun 008 PotentialChelsey S. mechanismsStraight, Young for lossS. Lee of andhair Guodongfollicle immune S. Liu. Hershey,privilege PA. in youngultraviolet Lee. Seoul, tanning Korea causes (the skinRepublic cancer. of). Chante Karimkhani, Lindsay Nicole + 297 patientsBundled paymentwith alopecia models areata for following actinic keratosis hepatitis . Joslyn B vaccination. Kirby, Jeffrey J 023 CD8Boyers,αα T Lisacells M contribute Schilling and to lichen Robert planus Dellavalle. independence New York, of NY; LAMP1- Washington, ChristopherMiller and DouglasRichardson S. Leslie., Elaine Hershey, Gilmore PA.and Brian Poligone. Rochester, NY. meditatedDC; Aurora, degranulation. CO and Denver, Bing CO. Li, Xiuwen Sun and Gang Wang. Xi’an, 009*298 CCL17Evaluation attenuates of actinic tumor keratosis immunity clinical by increasing practice regulatory guidelines . JoslynT cells Kirbyand , 314* China.Young adults who frequently indoor tan report decreased sun- Th2Thomas cells while P. Scharnitz, decreasing Elizabeth myeloid-derived S. Seiverling, suppressor Hadjh S. Ahrns cells andin tumor Sara S. 024 Immunomodulatoryprotective practices effects and lowof nanoparticlesrates of total bodyon the skin contact examinations. microenvironment.Ferguson. Hershey, Makoto PA. Sugaya, Sohshi Morimura, Tomonori Oka, hypersensitivityAlexander H Fischer response, Timothy in C57BL/6 Wang, Sewonhairless Kang mice. and Samreen Anna L.Jatana Chien., 299 HirakuVitamin Suga, D intake Tomomitsu and risk Miyagaki, of basal Yuichiro cell carcinoma Tsunemi, and Yoshihide squamous Asano, cell BrianBaltimore, C Palmer MD.and Lisa A DeLouise. Rochester, NY. Yayoicarcinoma Tada, Takafumi in US women Kadono and and men. Shinichi Eunyoung Sato. Tokyo,Cho, Sang Japan. Min Park, 025315* CapturingChildhood functional versus adulthood conservation sun exposure between and human skin skincancer and risk mouse in DC 010 DistinctiveShaowei Wu, downmodulation Wen-Qing Li and ofAbrar plasmacytoid A. Qureshi. Boston,dendritic MA cell and by vitamin systemsCaucasian for generating post-menopausal better women vaccines. in Eynav the Women’sKlechevsky Health. Saint Initiative.Louis, D3Providence, analogue inRI. its interferon-α production and chemotactic activity. MO.Katherine J. Ransohoff, Mina Sarah Ally, Marcia Stefanick, Elizabeth Keiser, 300 TakahiroComparing Suzuki cutaneous, Yoshiki Tokura. research Hamamatsu, funded by theJapan. National Institutes of 026* HumanKatrina skin Spaunhurst, is protected Kristopher by four functionallyKapphahn, Sherry and phenotypicallyPagoto, Catherine 011** AHealth wave of with regulatory the United T cells States into skin neonatal disease skin burden. mediates Lindsay tolerance Nicole to discreteMessina, populations Haley Hedlin, of resident JoAnn E Mansonand recirculating and Jean Y memoryTang. Redwood T cells. Rei City, commensalBoyers, Erika microbes L Hagstrom, . Tiffany Shivani C Scharschmidt Patel, Chante, Kimberly Karimkhani, S Vasquez, Cory Dunnick Hong- WatanabeCA; Stanford,, Ahmed CA; Gehad,San Diego, Chao CA; Yang, Cleveland, Laura Campbell, OH; Boston, Jessica MA Emberleyand Stony Anand Truong, Robert Sofia Dellavalle. V. Gearty, New MarielaYork, NY; L Pauli, Maywood, Audrey IL; Nosbaum, Charleston, Michael SC; Teague,Brook, Victor NY. Huang, Tiago R Matos, Thomas S. Kupper and Rachael Otto,Washington, James J DC;Moon, Aurora, Abul COK. Abbas,and Denver, Michael CO. A Fischbach and Michael 316 Clark.Objective Boston, and MA. subjective qualifiers of perceived skin aging process. 301 DavidComparing Rosenblum. students’ San Francisco, behaviors, CA; attitudes, Bethesda, andMD andknowledge Charlestown, on sun 027 NovelAna STAT3Paula Azambujainhibitor LLL12, Mary significantly Sanae Nakamura, reduces Thiago IL-17, F IL-22,Pires, Andreaand IFN- RVR MA.protection. Giselle Prado, Katherine Vandenberg, Emily Tongdee and gammaHorimoto, mRNA Rafael expression Alvim, Joséin psoriatic Eduardo PBMCs.Krieger Justin and Alexandre G Hastings C, XiaoliPereira. 012 KeratinMercedes 17 Florez-White.enhances the Miami,chemotaxis FL. of neutrophils through regulating Zhang,Cajamar, Jiayuh Brazil Lin, and Chenglong São Paulo, Li and Brazil. Henry K Wong. Columbus, OH. 302***chemokine The risk of CXCL1 cancer secretion in patients in keratinocyteswith psoriasis: viaA population-basedPI3k/AKT/NF-κB cohort 028*317 GILT-mediatedHeritability and processing correlation of a selfmap and of skinmelanoma hydration antigen measurements in thymic with epithelial cells promotes deletion and regulatory T cells. Karen Taraszka pathway.study in Er-Lethe United Dang, Kingdom.Liang Jin, Chang-xu Zelma C. ChiesaHan, Bing, Daniel Li, Man B Shin, Jiang Junko and environmental and life style factors of Brazilian population. Thiago Hastings, Matthew Rausch, Todd C. Metzger, Michael Waterfield, Jessica GangTakeshita, Wang. Alexis Xi’an, OgdieChina. and Joel Gelfand. Philadelphia, PA. F Pires, Ana Paula Azambuja, Mary Sanae Nakamura, Andrea RVR Cortez and Mark S. Anderson. Phoenix, AZ and San Francisco, CA. 013* Contributions of skin resident and recirculating memory T cells to Horimoto, Rafael Alvim, José Eduardo Krieger and Alexandre C Pereira. depigmentation in vitiligo. Jillian Richmond, Mehdi Rashighi, Priti Cajamar, Brazil and São Paulo, Brazil. Agarwal and John E Harris. Worcester, MA.

Notes:Notes:

1 11 84 PPosteroster P Presentationsresentations // aabstractbstract ttitlesitles

Adaptive Immunity & Vaccination 318014 HeritabilityAcne vaccines and targeting correlation secretory map of CAMPskin viscoelasticfactor of Propionibacterium measurements with Epidermal Structure & Barrier Function All orals [designated with an asterisk (*)] listed below are presented in the environmentalacnes. Chun-Ming and Huang life style. San factors Diego, of CA. Brazilian population. Mary Sanae All orals [designated with an asterisk (*)] listed below are presented in the Adaptive Immunity & Vaccination Minisymposium on Saturday, May 9, 2015, 015* NakamuraIdentifying, Ana Merkel Paula polyomavirus-specific Azambuja, Thiago F Pires, CD4+ Andrea and CD8+RVR T-cellsHorimoto, in Epidermal Structure & Barrier Function Minisymposium Friday, May 8, 2015, from 12:30-3:30 pm in Salon D, Hilton Atlanta. Orals designated by two asterisks RafaelMerkel Alvim, cell carcinoma José Eduardo patients’ Krieger tumor-infiltrating and Alexandre C Pereira. lymphocytes. Cajamar, Dafina from 2:00-5:00 pm in Salon C, Hilton Atlanta. Orals designated by two asterisks (**) will be presented during a Plenary Session. Orals designated by three BrazilIbrani and, Jayasri São GPaulo, Iyer, Brazil.Natalie Vandeven, Natalie Miller, Olga Afanasiev, (**) will be presented during a Plenary Session. Orals designated by three asterisks (***) will be presented during the Interdisciplinary Spotlight: Skin 319** FunctionalDavid Koelle characterization and Paul Nghiem. of AHRSeattle, promoter WA. polymorphism that asterisks (***) will be presented during the Interdisciplinary Spotlight: Skin Cancer Minisymposium on Friday, May 8, 2015, from 2:00 – 5:00 pm in the Grand 016* contributesRegulatory Tto cells reduced facilitate vitiligo cutaneous risk. Xiaowen wound Wang healing., Kai AudreyLi, Ling Liu,Nosbaum Zhe , Cancer Minisymposium on Friday, May 8, 2015, from 2:00 – 5:00 pm in the Grand Ballroom, Hilton Atlanta. Jian,Monika Gang Ettinger, Wang, Chunying Hong-An LiTruong, and Tianwen Mariela Gao. L Pauli, Xi’an, Sofia China. V. Gearty, Abul K. Ballroom, Hilton Atlanta. 320 ChildhoodAbbas and eczemaMichael is David associated Rosenblum. with anemiaSan Francisco, in 18 US CA. population-based 017 Quantification of CD69+CD103+ skin T cells in chronic atopic dermatitis. 001 RON2315: A novel human biologic for the topical treatment of psoriasis. studies. Jonathan Silverberg, Kerry E Drury.RM Chicago, IL. 335 A combination of keratinocyte activation with exposure to Th2 SeoHyeong KIM, Chang Ook Park, Jung U Shin, Ji Yeon Noh, Shan Jin, Thomas Gadek. Portola Valley, CA. 321 Eczema is associated with increased preventive healthcare and health interleukins is required to alter barrier properties in a reconstructed Hemin Lee, Jungsoo Lee, Thomas S. Kupper and Kwang Hoon Lee. Seoul, 002* Blockade for CD155-TIGIT interaction is an effective therapy for maintenance in US adults and children. Mark A Strom, Jonathan human epidermis. Yves Poumay, Évelyne De Vuyst, Séverine Giltaire, Korea (the Republic of) and Boston, MA. melanoma. Takashi Inozume, Tomonori Yaguchi, Yutaka Kawakami and Silverberg. Chicago, IL. Aline Chrétien, Catherine Lambert de Rouvroit and Michel Salmon. 018* Shared VH1-46 antibody gene usage in pemphigus vulgaris predicts Shinji Shimada. Chuo, Japan and Shinjyuku, Japan. 322* Melanoma screening consequences. Martin A Weinstock, Laura Ferris, Namur, Belgium and Les Isnes, Belgium. antibody cross-reactivity to desmoglein 3 and rotavirus VP6. Michael 003 Migratory DC temper subcutaneous immunity through key tolerance Melissa Saul, Alan Geller, Patricia Risica, Francis Solano, John Lagnese and 336* A reinnervated skin model: A new tool to study link between Jeffrey Tejada Cho, Christoph Ellebrecht, Christoph Matthias Hammers, pathways. Niroshana Anandasabapathy, Christopher Nirschl, Yong Liu, John Kirkwood. Providence, RI; Pittsburgh, PA and Boston, MA. innervation and aging. Manasi Chavan, Christine Jeanmaire, Carine Gopal Sapparapu, James Crowe and Aimee S Payne. Philadelphia, PA and Shamim Mollah, Rachel E. Feder, Pinru Wu, Peter Sage and Arlene H 323*** Alcohol consumption and risk of cutaneous basal cell carcinoma in Tedeschi, Laurent Misery and Nicolas Lebonvallet. Essey les Nancy, France Nashville, TN. Sharpe. Boston, MA and New York, NY. women and men. Abrar A. Qureshi, Shaowei Wu, Wen-Qing Li and and Brest, France. 019* Next generation T cell receptor sequencing reveals complex T cell 004 Rationale and design of a novel dendritic cell targeted vaccine for basal Eunyoung Cho. Providence, RI. 337 A parathyroid hormone family member TIP39 is expressed in the skin dynamics in Alopecia Areata . Annemieke de Jong, Luzhou Xing, Ali cell carcinoma. Karyn Haitz, Steven R Barthel, Yong Liu, Christopher 324 Natural hair color and among women in the United States. Wen- and regulates keratinocyte differentiation. Emi Sato, Jun Muto, Lingjuan Jabbari, Zhenpeng Dai, Vera H Price, Madeleine Duvic, David Norris, Nirschl, Ervin Epstein and Niroshana Anandasabapathy. Boston, MA and Qing Li, Xiang Gao, Shelley Tworoger, Jiali Han and Abrar A. Qureshi. Zhang, Chris Adase, James Asbury Sanford, Robert A. Lee and Richard L Maria Hordinsky, Julian Mackay-Wiggan, Raphael Clynes and Angela Oakland, CA. Providence, RI; University Park, PA; Boston, MA and Indianapolis, IN. Gallo. San Diego, CA and Aichi, Japan. Christiano. New York, NY; San Francisco, CA; Houston, TX; Denver, CO and 005 An ex vivo skin model that combines topical skin penetration and Th17 325 Dietary intake of folate and vitamins B6 and B12 and risk of psoriasis. 338 Microneedle-mediated delivery of vismodegib across skin. Hiep Xuan Minneapolis, MN. stimulation. Mary Bedard, Steven Cook, Leandro Santos, Jessica Neil, Eunyoung Cho, Tricia Li, Wen-Qing Li, Shaowei Wu and Abrar A. Qureshi. Nguyen, Ajay K Banga. Atlanta, GA. 020 Calcitonin gene-related peptide (CGRP) induces endothelial cells (EC) to Carlos Eduardo Peredo, Susan H Smith, Javier Cote-Sierra and Jon Lenn. Providence, RI and Boston, MA. 339 Ethnic differences in skin hydration and barrier function, as illustrated bias Langerhans cell (LC) antigen presentation towards a Th17 response Research Triangle Park, NC. 326 Epidemiology of genitourinary melanoma: 1992-2011. Benjamin Cohen, by facial mapping. Rainer Voegeli, Anthony V Rawlings, Pierre Seroul and Ritvathrough Vyas, induction Homayoun of Zargarsoluble Shoshtari mediators. and Wanhong Meg Rebecca Ding, Lori Gerstenblith. L Stohl, 006 Immunomodulatory effects of AM1030, a topical 5-HT2B receptor Beverley Summers. Northwich, United Kingdom; Kaiseraugst, Switzerland; John A Wagner, Linghui Xu and Richard David Granstein. New York, NY. antagonist in development for atopic dermatitis. Niklas Palmqvist, Max Cleveland, OH. Lyon, France and Medunsa, South Africa. 021* Elevated thymic stromal lymphopoietin expression in the skin blocks Siller, Anders Sjödin, Helena Arozenius, Christina Wenglén, Anna-Carin 327* Air pollution is associated with increased eczema prevalence and 340 Effects of H -antihistamines on expression of axon guidance molecules breast carcinogenesis. Shadmehr Demehri, Trevor J Cunningham, Sindhu 1 Ryde, Lars Pettersson, Cecilia Klint, Anna Pramhed, Anna Löfdahl and severity. Jonathan Silverberg, Parul Kathuria. Chicago, IL. in normal human epidermal keratinocytes. Yayoi Kamata, Azumi Manivasagam, Melissa Meyer, David Denardo, Raphael Kopan and Wayne Gunilla Ekström. Lund, Sweden. 328 Laboratory monitoring during isotretinoin therapy: A systematic review Sakaguchi, Yoshie Umehara, Mitsutoshi Tominaga, Hideoki Ogawa and Yokoyama. St. Louis, MO and Cincinnati, OH. 007 Phenotypic analysis of dendritic cells infiltrating a spontaneous model and meta-analysis . Thomas P. Scharnitz, Young S. Lee and Joslyn Kirby. Kenji Takamori. Urayasu, Japan. 022 Topical application of eupatilin ameliorates atopic dermatitis-like skin of basal cell carcinoma. Christopher Nirschl, Yong Liu, Pinru Wu, Karyn Hershey, PA. 341* Network analysis identifies MPZL3 as an essential regulator of lesions of NC/Nga mice. Young Min Park, Ji Hyun Lee, Ye Jin Lee and Jun Haitz and Niroshana Anandasabapathy. Boston, MA. 329 Association of keloids with systemic medical conditions: A retrospective epidermal differentiation that binds FDXR to induce reactive oxygen young Lee. Seoul, Korea (the Republic of). 008 Potential mechanisms for loss of hair follicle immune privilege in analysis. Donald A Glass, Prince Adotama. Dallas, TX. species. Aparna Bhaduri, Alexander Ungewickell and Paul Khavari. 023 CD8αα+ T cells contribute to lichen planus independence of LAMP1- patients with alopecia areata following hepatitis B vaccination. 330 Varicella vaccination is associated with increased prevalence of eczema Stanford, CA. meditated degranulation. Bing Li, Xiuwen Sun and Gang Wang. Xi’an, Christopher Richardson, Elaine Gilmore and Brian Poligone. Rochester, NY. in the US. Jonathan Silverberg, Jennifer C Li. Chicago, IL. 342 Development of an ex vivo human skin model to study skin barrier China. 009* CCL17 attenuates tumor immunity by increasing regulatory T cells and 331 Assessment of sun exposure while traveling to sunny destinations by repair. Joke Bouwstra, Tineke Berkers, Lolu Danso and Arnout Mieremet. Th2 cells while decreasing myeloid-derived suppressor cells in tumor 024 CanadiansImmunomodulatory during the effects winter season.of nanoparticles Sunil Kalia .on Vancouver, the contact Canada. hypersensitivity response in C57BL/6 hairless mice. Samreen Jatana, Leiden, Netherlands. microenvironment. Makoto Sugaya, Sohshi Morimura, Tomonori Oka, 332 Adolescent and young adult cutaneous lymphomas: Clinical spectrum 343 Lipid chain length reduction correlates with the skin barrier function Hiraku Suga, Tomomitsu Miyagaki, Yuichiro Tsunemi, Yoshihide Asano, andBrian autoimmunity. C Palmer and LisaGregory A DeLouise. Raymond Rochester, Delost, Jacqueline NY. Selph, Ritva 025 Capturing functional conservation between human skin and mouse DC in atopic eczema patients and inflammation plays a role in the altered Yayoi Tada, Takafumi Kadono and Shinichi Sato. Tokyo, Japan. Vyas, Kord Honda and Kevin D Cooper. Erie, PA and Cleveland, OH. epidermal lipid biosynthesis. Joke Bouwstra, Jeroen Van Smeden, Lolu 010 Distinctive downmodulation of plasmacytoid dendritic cell by vitamin 333 Advertisementsystems for generating of indoor better tanning vaccines. to minors Eynav through Klechevsky high. Saintschool Louis, MO. Danso, Michelle Janssens, Rob Vreeken, Abdoel El Ghalbzouri and Sjan D3 analogue in its interferon-α production and chemotactic activity. newspapers. Alyssa Self, Chante Karimkhani, Konstantin Grigoryan, Jason Lavrijsen. Leiden, Netherlands. Takahiro Suzuki, Yoshiki Tokura. Hamamatsu, Japan. 026* PelhamHuman Lottskin isand protected Robert byDellavalle. four functionally Aurora, CO; andNew phenotypically York, NY; Cincinnati, discrete populations of resident and recirculating memory T cells. Rei 344 The interaction between bicyclic monoterpene diol and neuropeptides 011** A wave of regulatory T cells into neonatal skin mediates tolerance to OH; New Haven, CT and Denver, CO. on keratinocyte cell proliferation and apoptosis. Nicole Weiler, Catherine commensal microbes . Tiffany C Scharschmidt, Kimberly S Vasquez, Hong- 334* IncidenceWatanabe and, Ahmed survival Gehad, of sebaceous Chao Yang, carcinoma Laura Campbell, in the UnitedJessica States.Emberley Teague, Victor Huang, Tiago R Matos, Thomas S. Kupper and Rachael Ding, Kanwaljit Brar, S. A Glick and Wei-Li Lee. Brooklyn, NY. An Truong, Sofia V. Gearty, Mariela L Pauli, Audrey Nosbaum, Michael Raghav Tripathi, Zhengyi Chen, Li Li and Jeremy Bordeaux. Cleveland, OH. 345 Detection of novel CYP11A1-derived secosteroids in the human Otto, James J Moon, Abul K. Abbas, Michael A Fischbach and Michael Clark. Boston, MA. 027 Novel STAT3 inhibitor LLL12 significantly reduces IL-17, IL-22, and IFN- epidermis and serum. Andrzej T Slominski, Tae-Kang Kim, Wei Li, Arnold David Rosenblum. San Francisco, CA; Bethesda, MD and Charlestown, E Postlethwaite and Robert C Tuckey. Memphis, TN; Birmingham, AL and MA. gamma mRNA expression in psoriatic PBMCs. Justin G Hastings, Xiaoli Zhang, Jiayuh Lin, Chenglong Li and Henry K Wong. Columbus, OH. Crawley, Australia. 012 Keratin 17 enhances the chemotaxis of neutrophils through regulating 346* Histamine impairs keratinocyte barrier function. Anna De Benedetto, κ 028* GILT-mediated processing of a self and melanoma antigen in thymic chemokine CXCL1 secretion in keratinocytes via PI3k/AKT/NF- B Takeshi Yoshida, Sade Fridy, Joo-Eun Sam Park and Lisa A Beck. Rochester, pathway. Er-Le Dang, Liang Jin, Chang-xu Han, Bing Li, Man Jiang and epithelial cells promotes deletion and regulatory T cells. Karen Taraszka NY. Gang Wang. Xi’an, China. Hastings, Matthew Rausch, Todd C. Metzger, Michael Waterfield, Jessica 347* Epidermal SIRT1 loss disrupts skin barrier integrity and sensitizes mice 013* Contributions of skin resident and recirculating memory T cells to Cortez and Mark S. Anderson. Phoenix, AZ and San Francisco, CA. to epicutaneous allergen challenge. Yu-Ying He, Mei Ming, Baozhong depigmentation in vitiligo. Jillian Richmond, Mehdi Rashighi, Priti Zhao, Christopher R. Shea, Shah Palak, Lei Qiang, Steven R. White and Agarwal and John E Harris. Worcester, MA. Diane Sims. Chicago, IL. Notes: Notes:

1 85 12 PPosteroster P Presentationsresentations / /a abstractbstract t titlesitles

Adaptive348 An optimized Immunity inexpensive & Vaccination emollient mixture improves barrier repair 014361 AcneMitochondria vaccines targeting move along secretory keratin CAMP 14, factorwith potential of Propionibacterium implications for All orals [designatedin murine skin. with Peter an asterisk M Elias (*)], Mao-Qiang listed below Man, are George presented Man, in Carolynthe acnes.epidermolysis Chun-Ming bullosa Huang simplex. San Diego, pathogenesis. CA. Asuka Suto, Riichiro Abe, AdaptiveCheung, Immunity Debra & Vaccination Crumrine, Melanie Minisymposium Hupe and on Zelee Saturday, Hill. San May Francisco, 9, 2015, CA 015* IdentifyingTakumi Koshiba, Merkel Yoichiro polyomavirus-specific Fujioka, Yusuke Ohba CD4+ and and Hiroshi CD8+ T-cells Shimizu. in from 12:30-3:30and London, pm in United Salon D, Kingdom. Hilton Atlanta. Orals designated by two asterisks MerkelSapporo, cell Japancarcinoma and Fukuoka, patients’ Japan. tumor-infiltrating lymphocytes. Dafina (**)349* will beX-ray presented crystal duringstructure a Plenary of the keratinSession. Orals1–keratin designated 10 heterodimer by three reveals 362 IbraniSustained, Jayasri transdermal G Iyer, Natalie delivery Vandeven, of methotrexate Natalie Miller, using Olga novel Afanasiev, in situ asterisks (***)a molecular will be basispresented for associated during the keratinopathies. Interdisciplinary Christopher Spotlight: Skin G Bunick . Davidforming Koelle hydrogel and Paul microneedles. Nghiem. Seattle, Arunprasad WA. Sivaraman, Ajay K Banga. Cancer MinisymposiumNew Haven, CT. on Friday, May 8, 2015, from 2:00 – 5:00 pm in the Grand 016* RegulatoryAtlanta, GA. T cells facilitate cutaneous wound healing. Audrey Nosbaum, Ballroom,350 Filaggrin Hilton Atlanta. mutations do not associate with Staphylococcus aureus skin 363 MonikaAnalysis Ettinger, of extracellular-matrix Hong-An Truong, and Mariela cell-adhesion L Pauli, Sofiagenes V. modulated Gearty, Abul by K. colonization in European American atopic dermatitis subjects. Takeshi Abbasmechanical and Michael massage David applied Rosenblum. in combination San Francisco, with CA. a cosmetic emulsion. + + 001 RON2315:Yoshida, Nicholas A novel humanRafael, Denisebiologic Babineau, for the topical Keli Artis, treatment Alexandre of psoriasis. Lockhart, 017 QuantificationCarla Abdo Brohem of ,CD69 BrunaCD103 Bastos skin Swinka,TRM cells Camila in chronic Miranda atopic de dermatitis. Carvalho, ThomasGloria David,Gadek .Mark Portola Boguniewicz, Valley, CA. Peck Ong, Anna De Benedetto, Jon SeoHyeongAna Cristina KIM , Weihermann,Chang Ook Park, Desirée Jung Cigaran U Shin, Schuck,Ji Yeon Noh,Nathaly Shan Boldrini, Jin, 002* BlockadeHanifin, forEric CD155-TIGIT L Simpson, interactionAmy S Paller, isEmma an effective Guttman-Yassky, therapy forLynda HeminVanessa Lee, Vitoriano Jungsoo daLee, Silva, Thomas Marco S. KupperAntonio and Trindade Kwang Costa, Hoon AdeleLee. Seoul, Helena melanoma.Schneider, TakashiRasika Mathias, Inozume Kathleen, Tomonori Barnes, Yaguchi, Donald Yutaka Leung Kawakami and Lisa and A KoreaRibeiro, (the Andre Republic Fujita of) andand MarcioBoston, Lorencini. MA. Sao Jose dos Pinhais, Brazil; ShinjiBeck. Shimada. Rochester, Chuo, NY; JapanBaltimore, and Shinjyuku, MD; Chapel Japan. Hill, NC; Denver, CO; Chicago, 018* SharedCuritiba, VH1-46 Brazil antibody and Sao genePaulo, usage Brazil. in pemphigus vulgaris predicts 003 MigratoryIL; New York, DC temper NY; Portland, subcutaneous OR; Los Angeles,immunity CA through and Boston, key tolerance MA. 364 antibodyA novel inhibitorcross-reactivity of plasmin to anddesmoglein urokinase 3 and suppresses rotavirus inflammation VP6. Michael 351 pathways.Nanotopography Niroshana facilitates Anandasabapathy in vivo transdermal, Christopher delivery Nirschl, of Yong high Liu, Jeffreyin keratinocytes Tejada Cho, in-vitro.Christoph Remo Ellebrecht, Campiche Christoph, Stephan Matthias Doppler, Hammers, Dominik Shamimmolecular Mollah, weight Rachel therapeutics E. Feder, Pinru through Wu, anPeter integrin-dependent Sage and Arlene H GopalImfeld, Sapparapu, Petra Lais, James Peter Crowe Wikstroem, and Aimee Anthony S Payne. V Rawlings Philadelphia, and Rainer PA and Sharpe.mechanism. Boston, Jubin MA Ryuand, NewLaura York, Walsh, NY. Suzanne Bock, Michael Koval, Nashville,Voegeli. TN.Kaiseraugst, Switzerland and Northwich, United Kingdom. 004 RationaleTheodora andMauro, design Russell of a Rossnovel and dendritic Tejal Desai. cell Santargeted Francisco, vaccine CA forand basal 019*365* NextRegulation generation and T disruptioncell receptor of sequencingthe site-specific reveals skin complex gene TKRT9 cell . Dongwon cellAtlanta, carcinoma. GA. Karyn Haitz, Steven R Barthel, Yong Liu, Christopher dynamicsKim, M. inZulfiquer Alopecia Hossain, Areata . AshleyAnnemieke Nieves, de Lihong Jong, LuzhouGu, Nicole Xing, Yang, Ali Seung 352* Nirschl,Tight junction Ervin Epstein barrier and dysfunction Niroshana Anandasabapathy. induced by epidermis-specific Boston, MA and Jabbari,Mi Oh, Zhenpeng Seunghyun Dai, Han, Vera Ji Qi,H Price, Janis MadeleineMarie Taube, Duvic, Sewon David Kang Norris, and Luis A Oakland,claudin-1 CA. ablation is sufficient to cause dermatitis in mice. Akiharu Kubo, MariaGarza. Hordinsky, Baltimore, Julian MD. Mackay-Wiggan, Raphael Clynes and Angela 005 AnTakashige ex vivo skin Hirano, model Mariko that Yokouchi,combines Hiroshi topical Kawasaki,skin penetration Toru Atsugi and and Th17 366 Christiano.Loss of loricrin New resultsYork, NY; in Sanimpaired Francisco, incorporation CA; Houston, of TX;fillagrin Denver, into CO and stimulation.Masayuki Amagai. Mary Bedard Tokyo,, StevenJapan and Cook, Kyoto, Leandro Japan. Santos, Jessica Neil, Minneapolis,cornified cell MN. envelopes. Yosuke Ishitsuka, Neil Box, Robert H Rice and 353 CarlosX-ray Eduardocrystallographic Peredo, Susananalysis H Smith,of the humanJavier Cote-Sierra profilaggrin and N-terminusJon Lenn. 020 CalcitoninDennis R gene-relatedRoop. Aurora, peptide CO and (CGRP)Davis, CA. induces endothelial cells (EC) to Researchprovides Triangle a mechanism Park, NC. for binding of interacting proteins. Christopher G 367 biasThe Langerhans LXR ligand cellVTP-38543 (LC) antigen represents presentation a new class towards of therapeutic a Th17 response Bunick, Richard Presland. New Haven, CT and Seattle, WA. throughagents inductionfor the treatment of soluble of atopicmediators. dermatitis. Wanhong Deepak Ding, LoriLala ,L YiStohl, Zhao, 006 Immunomodulatory effects of AM1030, a topical 5-HT2B receptor 354 antagonistStratifin inimplication development in forUVB atopic stress dermatitis. response andNiklas dermal Palmqvist remodeling., Max JohnShi AMeng, Wagner, Paul Linghui B. Noto, Xu Kerri and RichardK. Lipinski, David Yuri Granstein. E. Bukhtiyarov, New York, Linghang NY. Siller,Catherine Anders Gondran Sjödin, ,Helena Alexia Lebleu,Arozenius, Gilles Christina Oberto, YoleneWenglén, Ferreira, Anna-Carin Karine 021* ElevatedZhuang, thymic Colin Tice, stromal Wei lymphopoietin Zhao, Chengguo expression Dong, Stephen in the Lotesta, skin blocks Andrew Ryde,Cucumel Lars Pettersson,and Nouha Domloge.Cecilia Klint, Sophia Anna Antipolis, Pramhed, France.Anna Löfdahl and breastMarcus, carcinogenesis. Katerina Leftheris, Shadmehr Yajun Demehri Zheng,, TrevorKristi Fan,J Cunningham, Suresh B. Singh, Sindhu David 355 GunillaReconstructed Ekström. skinLund, models Sweden. with modulated expression of miR-203, a Manivasagam,Claremon and Melissa Gerard Meyer, M. McGeehan. David Denardo, Fort Washington, Raphael Kopan PA and and San Wayne Diego, 007 Phenotypickey microRNA analysis in the of epidermaldendritic differentiation,cells infiltrating aallowing spontaneous the in vitro model Yokoyama.CA. St. Louis, MO and Cincinnati, OH. ofstudy basal of cell the carcinoma. predicted Christopherconsequences, Nirschl based, Yong on Liu,a bioinformatic Pinru Wu, Karyn network 022368 TopicalEpidermis-specific application of mesotrypsineupatilin isameliorates involved inatopic corneocyte dermatitis-like desquamation skin Haitzmodel and of Niroshana the differentiation Anandasabapathy. process. JeanBoston, Marie MA. Botto, Catherine, Serre, lesionsand is of regulated NC/Nga mice.by an Youngintrinsic Min inhibitor, Park, Ji Hyunserpin Lee, B12. Ye Miyai Jin Lee Masashi and Jun, 008 PotentialChristophe mechanisms Capallere, Christellefor loss of Plaza, hair follicle Laurine immune Bergeron, privilege Nicolas in Esselin, youngHaruyo Lee. Yamanishi, Seoul, Korea Yuuko (the Matsumoto, Republic of). Mami Yamamoto, Yuko Hachiya, + patientsValère Busuttil with alopecia and Nouhaareata Domloge.following Sophiahepatitis Antipolis, B vaccination. France. 023 CD8Ryojiαα Tsuboi T cells and contribute Toshihiko to Hibino. lichen planusYokohama, independence Japan and ofTokyo, LAMP1- Japan. 356 ChristopherSpecific culture Richardson medium, Elaine to improve Gilmore keratinocytesand Brian Poligone. proliferation Rochester, andNY. 369 meditatedA natural degranulation. cosmetic active Bing ingredient Li, Xiuwen dedicatedSun and Gangto the Wang. needs Xi’an, of pregnant 009* CCL173D epidermis attenuates reconstruction. tumor immunity Christophe by increasing Capallere regulatory, Christelle T cellsPlaza, and China.woman’s skin. Stephanie Bredif, Sophie Leclere-Bienfait and Caroline Th2Marianne cells while Arcioni, decreasing Imane Garcia,myeloid-derived Eric Bauza, suppressor Jean Marie cells Botto in tumorand Nouha 024 ImmunomodulatoryBaudouin. Epernon, effects France. of nanoparticles on the contact microenvironment.Domloge. Sophia Antipolis, Makoto Sugaya France., Sohshi Morimura, Tomonori Oka, 370 hypersensitivityExpression of a responsenovel immunoglobulin in C57BL/6 hairless protein mice. in theSamreen skin and Jatana other, 357 HirakuExpression Suga, Tomomitsuof long non-coding Miyagaki, RNAs Yuichiro in the Tsunemi, skin: Study Yoshihide in cultured Asano, Brianepithelia. C Palmer Tongyu and LisaCao AWikramanayake DeLouise. Rochester,, Hunter NY. Mitchell. Miami, FL. Yayoihuman Tada, cells Takafumi and reconstructed Kadono and skinShinichi tissue. Sato. Nouha Tokyo, Domloge Japan. , Jean Marie 025371** Capturing NuMA/microtubule functional conservationinteractions arebetween critical human for asymmetric skin and mousecell divisions DC 010 DistinctiveBotto, Catherine, downmodulation Serre, Christelle of plasmacytoid Plaza, Laurine dendriticBergeron, cell Valère by vitamin Busuttil systemsand epidermal for generating morphogenesis. better vaccines. Lindsey Eynav Seldin Klechevsky, Terry Lechler.. Saint Durham,Louis, D3and analogue Christophe in its Capallere. interferon- Sophiaα production Antipolis, and France. chemotactic activity. MO.NC. 358 TakahiroImpact Suzukiof environmental, Yoshiki Tokura. particulate Hamamatsu, pollution Japan. on skin: effect of 026*372 HumanBiomarkers skin is of protected skin health by fourand barrierfunctionally efficiency. and Nidhinphenotypically Raj, Nicola Parisi, discrete populations of resident and recirculating memory T cells. Rei 011** APM wave10-like of regulatory particles Tapplied cells into on neonatalhuman skin skin cultured mediates cells tolerance and on to3D Anthony V Rawlings, Rainer Voegeli, Majella E Lane, Michael Munday and commensalreconstructed microbes epidermis, . Tiffany and Cstudy Scharschmidt of miRNAs, Kimberly expression. S Vasquez, Valère Hong- WatanabeSimon Gibbons., Ahmed London, Gehad, ChaoUnited Yang, Kingdom Laura and Campbell, Wurmisweg, Jessica Switzerland. Emberley AnBusuttil Truong,, Laurine Sofia V.Bergeron, Gearty, Catherine,Mariela L Pauli, Serre, Audrey Christelle Nosbaum, Plaza, NicolasMichael 373 Teague,SCARA3 Victor is required Huang, forTiago topically R Matos, delivered Thomas spherical S. Kupper oligonucleotide and Rachael Otto,Esselin, James Eric J Bauza,Moon, Christophe Abul K. Abbas, Capallere, Michael Jean A Fischbach Marie Botto and andMichael Nouha Clark.nanoconjugates Boston, MA. to penetrate the epidermal barrier. Quincy Song, Will DavidDomloge. Rosenblum. Sophia SanAntipolis, Francisco, France. CA; Bethesda, MD and Charlestown, 027 NovelBriley, STAT3 Suguna inhibitor Narayan, LLL12 Xiao-Qi significantly Wang, Chad reduces Mirkin IL-17, and IL-22, Amy S.and Paller. IFN- 359 MA.Endocannabinoid modulators influence skin barrier repair, gammaChicago, mRNA IL and expression Evanston, in IL. psoriatic PBMCs. Justin G Hastings, Xiaoli 012 Keratininflammation, 17 enhances proliferation the chemotaxis and differentiationof neutrophils through in mouse regulating irritant contact 374 Zhang,Nuclear Jiayuh IL-33 Lin, is Chenglonginvolved in Li cell and proliferation Henry K Wong. via Columbus,formation OH. of contractile chemokinedermatitis. CXCL1 Ehrhardt secretion Proksch in, Michaelkeratinocytes Soeberdt, via ClaudiaPI3k/AKT/NF- NeumannκB and 028* GILT-mediatedring in normal processing human epidermal of a self and keratinocytes. melanoma Hidetoshiantigen in Tsuda thymic, Mayumi pathway.Christoph Er-Le Abels. Dang Kiel,, Liang Germany Jin, Chang-xu and Bielefeld, Han, Bing Germany. Li, Man Jiang and epithelialKomine, cellsShin-ichi promotes Tominaga deletion and Mamitaro and regulatory Ohtsuki. T cells. Shimotsuke-shi, Karen Taraszka 360 GangNitric Wang. oxide Xi’an, differentially China. regulates epidermal proliferation in normal HastingsJapan., Matthew Rausch, Todd C. Metzger, Michael Waterfield, Jessica 013* Contributionsand inflamed ofskin. skin George resident Man and, Mao-Qiang recirculating Man, memoryCarolyn T Cheung, cells to Cortez and Mark S. Anderson. Phoenix, AZ and San Francisco, CA. depigmentationMelanie Hupe and in Petervitiligo. M Jillian Elias. Richmond San Francisco,, Mehdi CA. Rashighi, Priti Agarwal and John E Harris. Worcester, MA.

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1 13 86 PPosteroster P Presentationsresentations // aabstractbstract ttitlesitles

Adaptive Immunity & Vaccination 375014 InvolvementAcne vaccines of targeting the aryl hydrocarbon secretory CAMP receptor factor (AhR) of Propionibacterium in the murine 391* Calmodulin-like 5 interacts with 14-3-3-σ/stratifin to regulate late All orals [designated with an asterisk (*)] listed below are presented in the skinacnes. barrier Chun-Ming function. Huang Katharina. San Diego, Haas, CA. Susanne Grether-Beck, Wilhelm epidermal differentiation . Bryan Sun, Julia Ransohoff, Kun Qu, Vanessa Adaptive Immunity & Vaccination Minisymposium on Saturday, May 9, 2015, 015* Bloch,Identifying Jean Krutmann Merkel polyomavirus-specific and Charlotte Esser. Düsseldorf,CD4+ and CD8+Germany T-cells and in Köln, Lopez-Pajares, Lisa D Boxer and Paul Khavari. Stanford, CA. from 12:30-3:30 pm in Salon D, Hilton Atlanta. Orals designated by two asterisks Germany.Merkel cell carcinoma patients’ tumor-infiltrating lymphocytes. Dafina 392 Histological stratification of thick and thin plaque psoriasis identifies (**) will be presented during a Plenary Session. Orals designated by three 376 InterpretationIbrani, Jayasri G ofIyer, dermatological Natalie Vandeven, drug Nataliepenetration Miller, andOlga drug Afanasiev, effects using distinct molecular and clinical phenotype. Joel Mauricio Corrêa da Rosa, asterisks (***) will be presented during the Interdisciplinary Spotlight: Skin multipleDavid Koelle imaging and Paul tools. Nghiem. Gregory Seattle, Hamm , RaphaelWA. Legouffe, David Bonnel, Prannay Nadella, Jaehwan Kim, James G Krueger and Mayte Suarez- Cancer Minisymposium on Friday, May 8, 2015, from 2:00 – 5:00 pm in the Grand 016* AlainRegulatory Heron, T Fabien cells facilitate Pamelard cutaneous and Jonathan wound Stauber. healing. Lille, Audrey France. Nosbaum, Farinas. New York, NY. Ballroom, Hilton Atlanta. 377 ExpressionMonika Ettinger, of Orai3 Hong-Ancorrelates Truong, with aging-related Mariela L Pauli, changes Sofia V. in stress-Gearty, Abul K. 393 Temporal variations in sirtuin expression under normal and ultraviolet inducedAbbas and calcium Michael signaling David Rosenblum. in keratinocytes. San Francisco, Sumiko Denda CA. , Junichi B-induced conditions and their correlation to energy levels in normal + + 001 RON2315: A novel human biologic for the topical treatment of psoriasis. 017 Kumamoto,Quantification Kentaro of Takei, CD69 CD103 Makiko skin Goto, TRM cellsMasaharu in chronic Nagayama atopic anddermatitis. human epidermal keratinocytes . Edward Pelle, Kelly Dong and Nadine Thomas Gadek. Portola Valley, CA. MitsuhiroSeoHyeong Denda. KIM, Chang Yokohama, Ook Park, Japan; Jung Tokyo, U Shin, Japan Ji Yeon and Sapporo,Noh, Shan Japan. Jin, Pernodet. Melville, NY and New York, NY. 002* Blockade for CD155-TIGIT interaction is an effective therapy for 378 SVEP1Hemin plays Lee, Jungsooa crucial Lee, role Thomas in normal S. Kupperepidermal and function.Kwang Hoon L Samuelov Lee. Seoul,, Q. 394 Major differences between human atopic dermatitis phenotype and melanoma. Takashi Inozume, Tomonori Yaguchi, Yutaka Kawakami and Li,Korea R Bochner, (the Republic N Najor, of) J andKoetsier, Boston, N Malchin, MA. T. Goldsmith, M Grafi-Cohen, mouse models as determined by global genomic profiling. David Adrian Shinji Shimada. Chuo, Japan and Shinjyuku, Japan. 018* D.Shared Vodo, VH1-46 G Fainberg, antibody E Warshauer, gene usage T Rogers, in pemphigus A Ishida-Yamamoto, vulgaris predicts N Erez, Ewald, Shinji Noda, Saeko Nakajima, Thomas Litman, James G Krueger, 003 Migratory DC temper subcutaneous immunity through key tolerance Iantibody Goldberg, cross-reactivityA Irvine, L Shultz, to Kathy desmoglein Green, Jouni3 and Uitto,rotavirus Eli SprecherVP6. Michael and Mayte Suarez-Farinas, Kenji Kabashima and Emma Guttman-Yassky. New pathways. Niroshana Anandasabapathy, Christopher Nirschl, Yong Liu, OJeffrey Sarig. Philadelphia,Tejada Cho, Christoph PA; Tel Aviv, Ellebrecht, Israel; Chicago,Christoph IL; Matthias Asahikawa, Hammers, Japan; York, NY; Copenhagen, Denmark and Kyoto, Japan. Shamim Mollah, Rachel E. Feder, Pinru Wu, Peter Sage and Arlene H Dublin,Gopal Sapparapu, Ireland and James Bar Harbor, Crowe ME. and Aimee S Payne. Philadelphia, PA and 395 Analysis of CARD14 polymorphisms in pityriasis rubra pilaris: Activation Sharpe. Boston, MA and New York, NY. 379 T-cellNashville, independent TN. role for Langerhans cells in the epidermal stress- of NF-kB. Joshua Kingman, Q. Li, Hye Jin Chung, N Ross, Matthew S 004 Rationale and design of a novel dendritic cell targeted vaccine for basal 019* response.Next generation Julia Lewis T cell, Juliet receptor F Gibson sequencing and Michael reveals Girardi. complex New T Haven,cell CT. Keller, J. Andrews, O Sarig, D Fuchs-Telem, Eli Sprecher and Jouni Uitto. cell carcinoma. Karyn Haitz, Steven R Barthel, Yong Liu, Christopher 380 Improvementdynamics in Alopecia of Lox expression Areata . Annemieke in epidermis de Jongby Cichorium, Luzhou Xing, intybus. Ali Philadelphia, PA and Tel Aviv, Israel. Nirschl, Ervin Epstein and Niroshana Anandasabapathy. Boston, MA and ManasiJabbari, Chavan Zhenpeng, Corinne Dai, Vera Reymermier, H Price, Madeleine Veronique Duvic, Degrave, David Julie Norris, Saget, 396 Topical delivery of Hyaluronic acid in dermatomed human skin. Pooja Oakland, CA. StephaneMaria Hordinsky, Grenier Julianand Valerie Mackay-Wiggan, Andre-Frei. Raphael Lyon, France. Clynes and Angela Bakshi, Ajay K Banga. Atlanta, GA. 005 An ex vivo skin model that combines topical skin penetration and Th17 381 TightChristiano. junction New response York, NY; to San impaired Francisco, lipid CA; barrier. Houston, Theodora TX; Denver, Mauro ,CO Anna and 397 Exploring the metabolome effectively to advance skincare research. stimulation. Mary Bedard, Steven Cook, Leandro Santos, Jessica Neil, Celli,Minneapolis, Richard Sun,MN. Kyungho Park, Bishoy Goubran, Yoshikazu Uchida, Peter Tracy Shafizadeh. Durham, NC. Carlos Eduardo Peredo, Susan H Smith, Javier Cote-Sierra and Jon Lenn. 020 MCalcitonin Elias and gene-related Kenneth Feingold. peptide San (CGRP) Francisco, induces CA. endothelial cells (EC) to 398* Regulation of protein synthesis during keratinocyte differentiation. Research Triangle Park, NC. 382 Desmocollinbias Langerhans ectodomain cell (LC) antigenshedding presentation and cantharidin towards acantholysis a Th17 .response Ning Annie E Collier, Ronald C. Wek and Dan F Spandau. Indianapolis, IN. Lithrough, Moonhee induction Park, Zhi of Liusoluble and Luismediators. A. Diaz. Wanhong Chapel Hill, Ding NC., Lori L Stohl, 006 Immunomodulatory effects of AM1030, a topical 5-HT2B receptor 399* Topoisomerase 2β impacts gene-length bias in psoriasis through altered antagonist in development for atopic dermatitis. Niklas Palmqvist, Max 383* TheJohn role A Wagner, of TGF- βLinghui signaling-mediated Xu and Richard miR-486-3p David Granstein. on the New inhibition York, NY. of epidermal differentiation. Mrinal Kumar Sarkar, Andrew Johnston, Siller, Anders Sjödin, Helena Arozenius, Christina Wenglén, Anna-Carin 021* keratinElevated 17 thymic in the stromal pathogenesis lymphopoietin of psoriasis. expression Man Jiang in, Zhongbinthe skin blocksSun, Lin William R Swindell, Xianying Xing, Ariel Finkielsztein, Spiro Getsios and breast carcinogenesis. Shadmehr Demehri, Trevor J Cunningham, Sindhu Ryde, Lars Pettersson, Cecilia Klint, Anna Pramhed, Anna Löfdahl and Gao and Gang Wang. Xi’an, China and Urumuqi, China. Johann Eli Gudjonsson. Ann Arbor, MI and Chicago, IL. Manivasagam, Melissa Meyer, David Denardo, Raphael Kopan and Wayne Gunilla Ekström. Lund, Sweden. 384 IL-17A increases asymmetric stem cell divisions in imiquimod-induced 400 Ingredients and formulation that improve barrier function also enhance Yokoyama. St. Louis, MO and Cincinnati, OH. 007 Phenotypic analysis of dendritic cells infiltrating a spontaneous model psoriasis. Giselle Vitcov, Samuel Sklar, Jeffrey North, Sarah Arron, Karen antimicrobial peptide production. Richard Sun, Mao-Qiang Man, Melanie 022 Topical application of eupatilin ameliorates atopic dermatitis-like skin of basal cell carcinoma. Christopher Nirschl, Yong Liu, Pinru Wu, Karyn Horton, Alexandra Charruyer and Ruby Ghadially. San Francisco, CA. Hupe, Joan Wakefield and Peter M Elias. San Francisco, CA. lesions of NC/Nga mice. Young Min Park, Ji Hyun Lee, Ye Jin Lee and Jun Haitz and Niroshana Anandasabapathy. Boston, MA. 385 Discovery of natural products that provide multi-functional anti-aging 401 Improved differentiation of keratinocytes from human induced young Lee. Seoul, Korea (the Republic of). 008 Potential mechanisms for loss of hair follicle immune privilege in skin benefits . Bing C Mei, Cheng Hwang, Jolanta Idkowiak-Baldys, Daniel pluripotent stem cells by manipulation of developmental signaling 023 CD8αα+ T cells contribute to lichen planus independence of LAMP1- patients with alopecia areata following hepatitis B vaccination. Thorn Leeson, Uma Santhanam and John Lyga. Suffern, NY. pathways. Zongyou Guo, Chong Shen, Karl Gledhill, Abigail Coffman, meditated degranulation. Bing Li, Xiuwen Sun and Gang Wang. Xi’an, Christopher Richardson, Elaine Gilmore and Brian Poligone. Rochester, NY. 386 A cosmetic formulation containing ingredients that stimulate in vitro Satoru Shinkuma, Noriko Umegaki-Arao, Hasan Erbil Abaci, Claire Higgins, China. 009* CCL17 attenuates tumor immunity by increasing regulatory T cells and production of epidermal differentiation proteins improves in vivo Brian Gillette, Samuel K Sia and Angela Christiano. New York, NY. 024 Immunomodulatory effects of nanoparticles on the contact Th2 cells while decreasing myeloid-derived suppressor cells in tumor barrier function. Michelle D Hines, Geetha Kalahasti, Hanh Pham, David 402 Psoriasis severity is increased by alcohol abuse: An animal model of hypersensitivity response in C57BL/6 hairless mice. Samreen Jatana, microenvironment. Makoto Sugaya, Sohshi Morimura, Tomonori Oka, Gan and Tiffany C. Florence. Dallas, TX. alcohol abuse and psoriasis. Rhonda M Brand, Melissa Paglia and Louis D. Brian C Palmer and Lisa A DeLouise. Rochester, NY. Hiraku Suga, Tomomitsu Miyagaki, Yuichiro Tsunemi, Yoshihide Asano, 387 In vivo imaging and identification of the dermal-epidermal junction. Falo. Pittsburgh, PA. 025 Capturing functional conservation between human skin and mouse DC Yayoi Tada, Takafumi Kadono and Shinichi Sato. Tokyo, Japan. Rachel E Watson, Victoria Newton, Michael J Sherratt, Robert Bradley, 403 Regulation of aquaporin-3 levels in epidermal keratinocytes through systems for generating better vaccines. Eynav Klechevsky. Saint Louis, 010 Distinctive downmodulation of plasmacytoid dendritic cell by vitamin Anthony V Rawlings, Rainer Voegeli and Christopher E Griffiths. histone deacetylase inhibition. Wendy B Bollag, Vivek Choudhary, Karen MO. D3 analogue in its interferon-α production and chemotactic activity. Manchester, United Kingdom; Northwich, United Kingdom and Kagha and Lawrence Olala. Augusta, GA. 026* Human skin is protected by four functionally and phenotypically Takahiro Suzuki, Yoshiki Tokura. Hamamatsu, Japan. Kaiseraugst, Switzerland. 404* Novel insights in the mechanisms of epidermal maintenance by in vivo discrete populations of resident and recirculating memory T cells. Rei 011** A wave of regulatory T cells into neonatal skin mediates tolerance to 388 Targeted deletion of suprabasal keratins K2 and K10 causes upregulation imaging. Panteleimon Rompolas, Valentina Greco. New Haven, CT. commensal microbes . Tiffany C Scharschmidt, Kimberly S Vasquez, Hong- ofWatanabe K1 and K16., Ahmed Heinz Gehad, Fischer Chao, Lutz Yang, Langbein, Laura SilkeCampbell, Praetzel-Wunder, Jessica Emberley An Truong, Sofia V. Gearty, Mariela L Pauli, Audrey Nosbaum, Michael JuliaTeague, Reichelt, Victor Erwin Huang, Tschachler Tiago R Matos, and Leopold Thomas Eckhart. S. Kupper Vienna, and RachaelAustria; Otto, James J Moon, Abul K. Abbas, Michael A Fischbach and Michael Heidelberg,Clark. Boston, Germany MA. and Newcastle upon Tyne, United Kingdom. David Rosenblum. San Francisco, CA; Bethesda, MD and Charlestown, 389027 BiochemicalNovel STAT3 changesinhibitor underlying LLL12 significantly a keratoderma-like reduces IL-17, phenotype IL-22, and in IFN- MA. micegamma lacking mRNA suprabasal expression AP1 in transcriptionpsoriatic PBMCs. factor Justin function. G Hastings Ellen, RorkeXiaoli , 012 Keratin 17 enhances the chemotaxis of neutrophils through regulating GautamZhang, Jiayuh Adhikary, Lin, ChristieChenglong Young, Li and Robert Henry KH Wong.Rice, Peter Columbus, M Elias, OH. Debra chemokine CXCL1 secretion in keratinocytes via PI3k/AKT/NF-κB 028* Crumrine,GILT-mediated Miroslav processing Blumenberg of a self and and Richard melanoma Eckert. antigen Baltimore, in thymic MD; pathway. Er-Le Dang, Liang Jin, Chang-xu Han, Bing Li, Man Jiang and Davis,epithelial CA; Sancells Francisco, promotes CA deletion and New and York, regulatory NY. T cells. Karen Taraszka Gang Wang. Xi’an, China. 390 ComparativeHastings, Matthew genomics Rausch, identifies Todd C. filaggrin-deficientMetzger, Michael Waterfield, species ofJessica mammals. 013* Contributions of skin resident and recirculating memory T cells to LeopoldCortez and Eckhart Mark, BettinaS. Anderson. Strasser, Phoenix, Veronika AZ and Mlitz, San Francisco,Heinz Fischer CA. and Erwin depigmentation in vitiligo. Jillian Richmond, Mehdi Rashighi, Priti Tschachler. Vienna, Austria. Agarwal and John E Harris. Worcester, MA.

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87 1 14 PPosteroster P Presentationsresentations / /a abstractbstract t titlesitles

AdaptiveGene Therapy Immunity & Clinical & Vaccination Therapeutics 014416* AcneRegression vaccines of targeting cutaneous secretory squamous CAMP cell factor carcinomas of Propionibacterium induced by topical AllAll orals orals [designated [designated with with an an asterisk asterisk (*)] (*)] listed listed below below are are presented presented in thein the acnes.application Chun-Ming of PI3K/mTORHuang. San inhibitors.Diego, CA. X Yang, C Marshall, T Dentchev, AdaptiveGene Therapy Immunity & Clinical & Vaccination Therapeutics Minisymposium Minisymposium on Saturday, on Thursday, May 9, May2015, 7, 015* IdentifyingT Salah, S Shankar,Merkel polyomavirus-specific F Stauffer, A Lerchner, FCD4+ Seiler, and F KalthoffCD8+ T-cells and in John from2015, 12:30-3:30 from 2:00-5:00 pm in Salon pm in D, Salon Hilton AB, Atlanta. Hilton OralsAtlanta. designated Orals designated by two asterisks by two MerkelSeykora. cell Philadelphia,carcinoma patients’ PA and Basel, tumor-infiltrating Switzerland. lymphocytes. Dafina (**)asterisks will be (**)presented will be during presented a Plenary during Session. a Plenary Orals Session. designated Orals bydesignated three by 417 IbraniEtanercept, Jayasri Gfor Iyer, toxic Natalie epidermal Vandeven, necrolysis: Natalie A Miller,confirm Olga on Afanasiev, efficacy and asterisksthree asterisks (***) will (***) be presented will be presented during the during Interdisciplinary the Interdisciplinary Spotlight: Spotlight: Skin Skin Davidsafety. Koelle Biagio and Didona Paul Nghiem., Andrea Seattle, Paradisi, WA.Dario Didona and Damiano Abeni. CancerCancer Minisymposium Minisymposium on on Friday, Friday, May May 8, 8,2015, 2015, from from 2:00 2:00 – 5:00 – 5:00 pm pm in thein the Grand Grand 016* RegulatoryRome, Italy. T cells facilitate cutaneous wound healing. Audrey Nosbaum, Ballroom,Ballroom, Hilton Hilton Atlanta. Atlanta. 418* MonikaPhase Ettinger, I clinical trial Hong-An for recessive Truong, dystrophic Mariela L Pauli, epidermolysis Sofia V. Gearty,bullosa Abulusing K. Abbasgenetically and Michael corrected David autologousRosenblum. keratinocytes. San Francisco, Zurab CA. Siprashvili, Ngon T 017 Quantification of CD69+CD103+ skin T cells in chronic atopic dermatitis. 001405* RON2315:Autologous A novel fibroblasts human therapybiologic for recessivethe topical dystrophic treatment epidermolysis of psoriasis. Nguyen, Emily Gorell, Kylie Loutit, RMPhuong Khuu, Louise Kimiko Furukawa, Thomasbullosa. Gadek Joanna. Portola Jackow Valley,, Matthias CA. Titeux, Soeli Charbonnier and Alain SeoHyeongH Peter Lorenz, KIM, Chang Thomas Ook H Park,Leung, Jung Douglas U Shin, R Keene,Ji Yeon Noh,Paul Khavari,Shan Jin, Alfred 002* BlockadeHovnanian. for CD155-TIGIT Paris, France. interaction is an effective therapy for HeminLane, Lee, Jean Jungsoo Y Tang andLee, M.Thomas Peter S.Marinkovich. Kupper and Stanford,Kwang Hoon CA; Lee.Portland, Seoul, OR 406 melanoma.Steady state Takashi pharmacokinetics, Inozume, Tomonori tolerability Yaguchi, and Yutaka safety Kawakami of XP23829, and a Koreaand (thePalo Republic Alto, CA. of) and Boston, MA. Shinjinovel Shimada. fumaric Chuo, acid esterJapan (FAE) and Shinjyuku,for the treatment Japan. of moderate-to-severe 018*419** Shared Site-specific VH1-46 antibodygenome editing gene usage using in CRISPR/Cas9pemphigus vulgarisand TALENs predicts for 003 Migratoryplaque psoriasis. DC temper Lee subcutaneous N Clark, Alice immunity B Gottlieb, through Richard key Kim tolerance and Dmitri antibodycorrection cross-reactivity of iPS cells derived to desmoglein from dominant 3 and rotavirus dystrophic VP6. epidermolysisMichael pathways.Lissin. Boston, Niroshana MA and Anandasabapathy Santa Clara, CA., Christopher Nirschl, Yong Liu, Jeffreybullosa. Tejada Satoru Cho ,Shinkuma Christoph, ZongyouEllebrecht, Guo Christoph and Angela Matthias Christiano. Hammers, New York, 407 ShamimPentobra: Mollah, A novel Rachel antimicrobial E. Feder, Pinru compound Wu, Peter with Sage lytic and Arleneactivity H against GopalNY. Sapparapu, James Crowe and Aimee S Payne. Philadelphia, PA and Sharpe.Propionibacterium Boston, MA and acnes. New George York, NY. W Agak, Nathan W Schmidt, Stephanie 420 Nashville,Cytokine-based TN. immunotherapy induces senescence in human 004 RationaleDeshayes, and Yang design Yu, Alyssa of a novel Blacker, dendritic Jackson cellChamper, targeted Wujing vaccine Xian, for basal 019* Nextmelanomas. generation Martin T cell receptorRöcken, Thomas sequencing Wieder, reveals Cristina complex Boss, T Ellencell Brenner, cellStephanie carcinoma. Kao, Karyn Andrea Haitz Kasko,, Steven Gerard R Barthel, C. L. Wong Yong andLiu, JennyChristopher Kim. Los dynamicsHeidi Braumüller, in Alopecia Claudia Areata Schulz, . Annemieke Alexander de Jong Scheu,, Luzhou Claus Xing,Garbe, Ali Tobias Nirschl,Angeles, Ervin CA. Epstein and Niroshana Anandasabapathy. Boston, MA and Jabbari,Feuchtinger Zhenpeng and Dai, Alfred Vera Königsrainer. H Price, Madeleine Tübingen, Duvic, Germany. David Norris, 408* Oakland,Hematopoietic CA. cell transplantation (HCT) for recessive dystrophic 421 MariaEpigenetic Hordinsky, changes Julian in Mackay-Wiggan, the GPi-linked Raphaelbiosynthetic Clynes pathway and Angela underlie 005 Anepidermolysis ex vivo skin model bullosa that (RDEB): combines reduced topical intensity skin penetration conditioning and (RIC) Th17 has Christiano.down regulation New York, of NY;CD52 San and Francisco, resistance CA; ofHouston, CTCL patients TX; Denver, to CO and stimulation.a better outcome Mary Bedard than, Stevenmyeloablative Cook, Leandro conditioning Santos, Jessica (MAC). Jakub Neil, Tolar , Minneapolis,alemtuzumab. MN. Ga-Young Lee, Jessica Emberley Teague, Ahmed Gehad, CarlosJohn Eduardo McGrath, Peredo, Mark J.Susan Osborn, H Smith, Douglas Javier R Keene, Cote-Sierra Kristen and Hook, Jon Lenn.Maria 020 CalcitoninElizabeth gene-related Lowry, David peptide C Fisher, (CGRP) Thomas induces S. Kupper endothelial and Rachael cells Clark. (EC) to ResearchHordinsky, Triangle David Park, Timothy NC. Woodley, Mei Chen, Alain Hovnanian, Katsuto biasBoston, Langerhans MA and cell Seoul, (LC) antigenKorea (the presentation Republic of). towards a Th17 response 422* throughThe effects induction of bisphosphonates of soluble mediators. on ectopic Wanhong soft Ding tissue, Lori mineralizationL Stohl, 006 ImmunomodulatoryTamai, Bruce Blazar effects and John of Wagner.AM1030, Minneapolis, a topical 5-HT MN;2B receptor London, United antagonistKingdom; in Portland, development OR; Los for Angeles, atopic dermatitis. CA; Paris, France Niklas andPalmqvist Osaka,, MaxJapan. Johncaused A Wagner, by mutations Linghui Xu in andthe ABCC6Richard gene: David Potential Granstein. treatment New York, of NY. PXE. 409* Siller,Novel Anders long-non-coding Sjödin, Helena RNA Arozenius, in melanoma: Christina MIRAT Wenglén, a biomarker Anna-Carin of small 021* ElevatedQ. Li, John thymic Paul stromal Sundberg, lymphopoietin Michael A Levine, expression Joshua in Kingman the skin andblocks Jouni Ryde,molecule Lars Pettersson, inhibitor response. Cecilia Klint, Martina Anna SanlorenzoPramhed, , AnnaIgor Vujic,Löfdahl Christian and breastUitto. carcinogenesis. Philadelphia, ShadmehrPA and Bar DemehriHarbor, , ME.Trevor J Cunningham, Sindhu GunillaPosch, Ekström. Kevin Lai, Lund, Kevin Sweden. Lin, Deborah Stephanie Gho, Adrian Moy, Abhinay 423 Manivasagam,ONC201 induces Melissa apoptosis, Meyer, Davidinhibits Denardo, proliferation, Raphael and Kopan affects and Waynecell cycle 007 PhenotypicGajjala and analysis Susana of Ortiz-Urda. dendritic cellsSan Francisco,infiltrating CA. a spontaneous model Yokoyama.in cutaneous St. Louis, T-cell MO lymphoma and Cincinnati, cells. Xiang OH. Zhang, Xiao Ni, Timothy 410 of Drugbasal repurposing cell carcinoma. for dermatomyositisChristopher Nirschl using, Yong public Liu, Pinru expression Wu, Karyn datasets. 022 TopicalLangridge application and Madeleine of eupatilin Duvic. amelioratesHouston, TX. atopic dermatitis-like skin HaitzHyunje and NiroshanaGrace Cho ,Anandasabapathy. David F Fiorentino, Boston, Marina MA. Sirota and Kavita Sarin. 424 lesionsAutosomal of NC/Nga dominant mice. transgradientYoung Min Park palmoplantar, Ji Hyun Lee, keratodermaYe Jin Lee and (PPK) Jun 008 PotentialStanford, mechanismsCA. for loss of hair follicle immune privilege in youngand Lee.hypotrichosis Seoul, Korea treated (the Republicadequately of). with 13-cis retinoic acid and + 411* patientsAllogeneic with mesenchymal alopecia areata stromal following cell therapyhepatitis for childrenB vaccination. with recessive 023 CD8acitretin:αα T cells a contributenew phenotype to lichen of PPK planus with independencecongenital alopecia of LAMP1- and update Christopherdystrophic Richardson epidermolysis, Elaine bullosa: Gilmore an andopen-label, Brian Poligone. phase 1,Rochester, single-centre NY. meditatedon palmoplantar degranulation. keratoderma-congenital Bing Li, Xiuwen Sun alopecia and Gang syndrome. Wang. Xi’an, Heather 009* CCL17trial attenuates. Gabriela Petrof tumor, Su immunity M Lwin, Magdalenaby increasing Martinez-Quiepo, regulatory T cells Alya and China.Irina Cohn, Neil Korman. Cleveland, OH. Th2Abdul-Wahab, cells while decreasing Simon Tso, myeloid-derived Jemima Mellerio, suppressor Ineke Slapen-Cortenbach, cells in tumor 024425*** Immunomodulatory Intrinsic resistance effects to smoothened of nanoparticles inhibitors onin thesporadic contact basal cell microenvironment.Jaap J Boelens, Jakub Makoto Tolar, Sugaya Paul Veys,, Sohshi Tendai Morimura, Kadiyirire, Tomonori Mercy Ofuya,Oka, hypersensitivitycarcinoma. Prajakta response Jaju ,in Melika C57BL/6 Rezaee, hairless Alexander mice. Samreen Lee, Jean Jatana Y Tang, and HirakuJanet Suga, L Peacock, Tomomitsu Anna Miyagaki,Martinez Yuichiroand John Tsunemi, McGrath. Yoshihide London, Asano,United BrianKavita C Palmer Sarin. andStanford, Lisa A CA. DeLouise. Rochester, NY. YayoiKingdom; Tada, Takafumi Utrecht, KadonoNetherlands and Shinichiand Minneapolis, Sato. Tokyo, MN. Japan. 025426* CapturingAssessment functional of amlexanox, conservation an antagonist between of nonsensehuman skin mediated and mouse mRNA DC 010412* DistinctiveA novel therapeutic downmodulation inhibits ofRac1 plasmacytoid mediated invasion dendritic and cell metastasis by vitamin in systemsdecay for(NMD), generating for the treatmentbetter vaccines. of RDEB. Eynav Velina Klechevsky Atanasova. Saint, Q. Louis, Jiang, D3a analogue newly described in its interferon- in vivo modelα production of human and melanoma. chemotactic M. CG activity. Winge , MO.Jouni Uitto and Andrew P South. Philadelphia, PA. TakahiroJoanna Suzuki Kovalski,, Yoshiki Ngon Tokura. T Nguyen, Hamamatsu, Diane Wu, Japan. Ashley Zehnder, Paul Khavari 026*427* HumanDifferentiating skin is protected endothelial by four cellsfunctionally from human and phenotypicallyinduced pluripotent stem 011** A waveand M. of Peter regulatory Marinkovich. T cells into Stanford, neonatal CA. skin mediates tolerance to discretecells. Abigailpopulations Coffman of, residentZongyou andGuo, recirculating Chong Shen, Karl memory Gledhill, T cells. Hasan Rei 413* commensalTopically deliveredmicrobes spherical. Tiffany nucleicC Scharschmidt acid nanoconjugates, Kimberly S Vasquez, targeting Hong- WatanabeErbil Abaci,, Ahmed Satoru Gehad, Shinkuma, Chao ClaireYang, LauraHiggins, Campbell, Brian Gillette, Jessica EmberleySamuel K Sia AnTNF Truong, improve Sofia the V. psoriaticGearty, Mariela phenotype. L Pauli, Katherine Audrey LewandowskiNosbaum, Michael, Weston Teague,and Angela Victor Christiano.Huang, Tiago New R Matos, York, NY.Thomas S. Kupper and Rachael Otto,Daniel, James Richard J Moon, Kang, Abul David K. Abbas,Giljohann, Michael Chad A MirkinFischbach and andAmy MichaelS. Paller. 428* Clark.Investigation Boston, MA. into the safety and efficacy of human ES/iPS-derived DavidChicago, Rosenblum. IL; Skokie, San IL Francisco, and Evanston, CA; Bethesda, IL. MD and Charlestown, 027 Novelkeratinocytes STAT3 inhibitor for therapeutic LLL12 significantly reprogramming reduces . HansonIL-17, IL-22, Zhen and, Elizaveta IFN- 414 MA.Electrophilic nitro-fatty acids suppress allergic contact dermatitis in gammaBashkirova, mRNA Sandra expression Melo, in Lingjie psoriatic Li, Jessica PBMCs. Torkelson, Justin G EricHastings Liaw, Xiaoliand 012 Keratinan experimental 17 enhances model. the chemotaxis Alicia R Mathers of neutrophils, Cara Carey, through Meghan regulating Killeen, Zhang,Anthony Jiayuh Oro. Lin, Stanford, Chenglong CA. Li and Henry K Wong. Columbus, OH. chemokineSchopfer JCXCL1 Francisco, secretion Bruce in Freeman keratinocytes and Louis via D. PI3k/AKT/NF- Falo. Pittsburgh,κB PA. 028* GILT-mediated processing of a self and melanoma antigen in thymic 415 pathway.Low dose Er-Le irradiation Dang, Liang kills Jin, malignant Chang-xu T Han,cells, Bing spares Li, Manbenign Jiang T cellsand and epithelial cells promotes deletion and regulatory T cells. Karen Taraszka Gangis a Wang.potentially Xi’an, China.curative therapy for mycosis fungoides. Rachael Clark, Hastings, Matthew Rausch, Todd C. Metzger, Michael Waterfield, Jessica 013* ContributionsElizabeth Lowry, of skin Tiago resident R Matos, and Victor recirculating Huang, Rei memory Watanabe, T cells Ahmed to Cortez and Mark S. Anderson. Phoenix, AZ and San Francisco, CA. depigmentationGehad, Jessica Emberleyin vitiligo. Teague,Jillian Richmond Phillip Devlin, Mehdi and Rashighi, Thomas Priti S. Kupper. AgarwalBoston, and MA. John E Harris. Worcester, MA. Notes:Notes:

1 15 88 PPoster PPresentations / abstract titles

Adaptive Immunity & Vaccination 014Genetic Acne vaccinesDisease targeting & Gene secretory Regulation CAMP factor of Propionibacterium 441* MCP-1 is overexpressed by Tsc2-null skin fibroblasts in a mouse model All orals [designated with an asterisk (*)] listed below are presented in the All oralsacnes. [designated Chun-Ming with anHuang asterisk. San (*)] Diego, listed CA. below are presented in the of tuberous sclerosis with targeted disruption of Tsc2. Shaowei Li, Peter Adaptive Immunity & Vaccination Minisymposium on Saturday, May 9, 2015, 015*Genetic Identifying Disease & GeneMerkel Regulation polyomavirus-specific Minisymposium CD4+ on Friday,and CD8+ May T-cells 8, 2015, in Klover, Rajesh L. Thangapazham, Ji-an Wang, Joel Moss and Thomas N from 12:30-3:30 pm in Salon D, Hilton Atlanta. Orals designated by two asterisks from 2:00-5:00Merkel cellpm carcinomain Room 204-207, patients’ Hilton tumor-infiltrating Atlanta. Orals designated lymphocytes. by Dafina two Darling. Bethesda, MD. rul (**) will be presented during a Plenary Session. Orals designated by three asterisksIbrani (**) ,will Jayasri be presented G Iyer, Natalie during Vandeven, a Plenary Natalie Session. Miller, Orals Olga designated Afanasiev, by 442 Dsp : A spontaneous mouse mutation in desmoplakin as a model asterisks (***) will be presented during the Interdisciplinary Spotlight: Skin three asterisksDavid Koelle (***) and will Paulbe presented Nghiem. Seattle,during the WA. Interdisciplinary Spotlight: Skin of Carvajal-Huerta Syndrome. Heather Fairfield, John Paul Sundberg, Cancer Minisymposium on Friday, May 8, 2015, from 2:00 – 5:00 pm in the Grand 016*Cancer MinisymposiumRegulatory T cells on facilitate Friday, May cutaneous 8, 2015, wound from 2:00 healing. – 5:00 Audrey pm in Nosbaum the Grand, Christopher S Potter, Laura G Reinholdt, David E Bergstrom, Belinda S Ballroom, Hilton Atlanta. Ballroom,Monika Hilton Ettinger, Atlanta. Hong-An Truong, Mariela L Pauli, Sofia V. Gearty, Abul K. Harris, Ian Greenstein, Soheil S Dadras, Bruce T Liang, Paul N Schofield Abbas and Michael David Rosenblum. San Francisco, CA. and C. Herbert Pratt. Bar Harbor, ME; Farmington, CT and Cambridge, 017 Quantification of CD69+CD103+ skin T cells in chronic atopic dermatitis. 001 RON2315: A novel human biologic for the topical treatment of psoriasis. 429 Assimilating transcriptional profilesRM from CCLE lesional skin United Kingdom. Thomas Gadek. Portola Valley, CA. SeoHyeongand peripheral KIM ,blood Chang offers Ook Park, a comprehensive Jung U Shin, Ji Yeonmodel Noh, of disease Shan Jin, 443 Meta-analysis of the TNIP1 region in psoriasis identifies two 002* Blockade for CD155-TIGIT interaction is an effective therapy for Heminpathogenesis. Lee, Jungsoo Rama Lee, Dey-Rao Thomas, Animesh S. Kupper A. Sinha. and Kwang Buffalo, Hoon NY. Lee. Seoul, independent association signals. Kristina Marie Lee, Joanne Nititham, melanoma. Takashi Inozume, Tomonori Yaguchi, Yutaka Kawakami and 430* KoreaDDX6 (theorchestrates Republic humanof) and epidermalBoston, MA. progenitor function through the Kimberly E Taylor, Rashmi Gupta, Richard Ahn, Haoyan Chen, Jianjun Liu, Shinji Shimada. Chuo, Japan and Shinjyuku, Japan. 018* SharedmRNA degradationVH1-46 antibody and translationgene usage inpathways. pemphigus George vulgaris Sen, Yingpredicts Wang Mark Seielstad, Averil Ma, Anne M Bowcock, Lindsey A Criswell, Mona 003 Migratory DC temper subcutaneous immunity through key tolerance antibodyand Yifang cross-reactivity Chen. La Jolla, CA. to desmoglein 3 and rotavirus VP6. Michael Stahle and Wilson Liao. San Francisco, CA; Shanghai, China; Singapore, pathways. Niroshana Anandasabapathy, Christopher Nirschl, Yong Liu, 431* JeffreyTrans-ethnic Tejada genome-wide Cho, Christoph meta-analysis Ellebrecht, Christoph identifies Matthias multiple Hammers, novel Singapore; London, United Kingdom and Stockholm, Sweden. Shamim Mollah, Rachel E. Feder, Pinru Wu, Peter Sage and Arlene H Gopalassociations Sapparapu, and Jamesreveals Crowe ethnic and heterogeneity Aimee S Payne. of psoriasisPhiladelphia, susceptibility. PA and 444* Dominant de novo GJA1 mutations cause erythrokeratodermia Sharpe. Boston, MA and New York, NY. Nashville,Xianyong YinTN., Hui QI Low, Mark Seielstad, Wilson Liao, Mona Stahle, variabilis. Lynn Boyden, Brittany Craiglow, Jing Zhou, Ronghua Hu, Erin 004 Rationale and design of a novel dendritic cell targeted vaccine for basal 019* NextAndre generation Franke, Xuejun T cell Zhang receptor and sequencingJianjun Liu. revealsSingapore, complex Singapore; T cell San Loring, Kimberly Morel, Christine Lauren, Richard Lifton, Amy S Paller and cell carcinoma. Karyn Haitz, Steven R Barthel, Yong Liu, Christopher dynamicsFrancisco, in CA; Alopecia Stockholm, Areata Sweden; . Annemieke Kiel, Germany de Jong ,and Luzhou Hefei, Xing, China. Ali Keith A Choate. New Haven, CT; New York, NY and Chicago, IL. Nirschl, Ervin Epstein and Niroshana Anandasabapathy. Boston, MA and 432 Jabbari,RNA recognition Zhenpeng Dai,motif Vera of HLEMD3 Price, Madeleineas a key player Duvic, in Davidthe pathogenesis Norris, of 445 Analysis of transcriptomes from palmoplantar pustulosis and Oakland, CA. MariaBuschke–Ollendorff Hordinsky, Julian syndrome. Mackay-Wiggan, Shota Takashima Raphael ,Clynes Yasuyuki and Fujita, Angela Shotaro palmoplantar pustular psoriasis suggests that they may not be different 005 An ex vivo skin model that combines topical skin penetration and Th17 Christiano.Suzuki, Nao Saito,New York, Toshifumi NY; San Nomura Francisco, and CA;Hiroshi Houston, Shimizu. TX; Sapporo,Denver, CO and clinical entities. Robert Bissonnette, Mayte Suarez-Farinas, Carrie stimulation. Mary Bedard, Steven Cook, Leandro Santos, Jessica Neil, Minneapolis,Japan. MN. Brodmerkel, Judilyn Fuentes Duculan, Kathleen M Bonifacio and James G Carlos Eduardo Peredo, Susan H Smith, Javier Cote-Sierra and Jon Lenn. 020433 CalcitoninEpigenetic gene-related modulation peptide of skin (CGRP)equivalents induces by cosmeticendothelial ingredients. cells (EC) to Krueger. Montreal, Canada; New York, NY and Spring House, PA. Research Triangle Park, NC. biasJin Namkoong Langerhans, Dale cell G(LC) Kern, antigen Remona presentation Gopaul, Elisabeth towards Lehigh, a Th17 Anna response J 446** Psoriasis drug development and GWAS interpretation through in silico through induction of soluble mediators. Wanhong Ding, Lori L Stohl, analysis of transcription factor binding sites. William R Swindell, Mrinal 006 Immunomodulatory effects of AM1030, a topical 5-HT2B receptor Langerveld and Helen Knaggs. Provo, UT and Kalamazoo, MI. antagonist in development for atopic dermatitis. Niklas Palmqvist, Max 434* JohnThe lncRNAA Wagner, FLJ46906 Linghui alters Xu and expression Richard David of aging-associated Granstein. New proteins York, NY. Kumar Sarkar, Philip E. Stuart, John J Voorhees, James T Elder, Andrew Siller, Anders Sjödin, Helena Arozenius, Christina Wenglén, Anna-Carin 021* Elevatedthrough bindingthymic stromal to AP-1 lymphopoietinand NF-κB. Kazuyuki expression Yo, Thomas in the M. skin Ruenger. blocks Johnston and Johann Eli Gudjonsson. Ann Arbor, MI. Ryde, Lars Pettersson, Cecilia Klint, Anna Pramhed, Anna Löfdahl and breastProvidence, carcinogenesis. RI and Yokohama, Shadmehr Japan. Demehri, Trevor J Cunningham, Sindhu 447 Buschke-Ollendorff syndrome in the absence of LEMD3 mutation. Gunilla Ekström. Lund, Sweden. 435 Manivasagam,TALEN-induced Melissa mutations Meyer, confirm David Denardo, Col17a1 Raphaelas a genetic Kopan modifierand Wayne of Joshua L Owen, Christy E Purnadi and Donald A Glass. Dallas, TX. 007 Phenotypic analysis of dendritic cells infiltrating a spontaneous model Yokoyama.junctional St. epidermolysis Louis, MO and bullosa Cincinnati, in mice. OH. Thomas James Sproule, 448* Functional genomics of the ULBP6 locus reveals a critical role for of basal cell carcinoma. Christopher Nirschl, Yong Liu, Pinru Wu, Karyn 022 TopicalJohn Paul application Sundberg, ofBenjamin eupatilin E Low,ameliorates Kathleen atopic A Silva, dermatitis-like Deepak Reyon, skin CTCF-mediated long-range interactions in alopecia areata. Gina Marie Haitz and Niroshana Anandasabapathy. Boston, MA. lesionsKeith Joung, of NC/Nga Michael mice. V Wiles Young and Min Derry Park C, Ji Roopenian. Hyun Lee, YeBar Jin Harbor, Lee and ME; Jun DeStefano, Lynn Petukhova, Esther Drill, Zhenpeng Dai, Li Bian, Raphael 008 Potential mechanisms for loss of hair follicle immune privilege in youngCharlestown, Lee. Seoul, MA Koreaand Cambridge, (the Republic MA. of). Clynes and Angela Christiano. New York, NY. + patients with alopecia areata following hepatitis B vaccination. 023436* CD8Somaticαα T cellsactivating contribute RAS mutations to lichen planuscause vascularindependence tumors of including LAMP1- 449 Multiple facial vellus hair cysts, ear pits, lipomas, macrocephaly, joint Christopher Richardson, Elaine Gilmore and Brian Poligone. Rochester, NY. meditatedpyogenic granuloma. degranulation. Young Bing H. LiLim, Xiuwen, Stephanie Sun andDouglas, Gang ChristineWang. Xi’an, J. Ko, laxity and cardiac defects: A novel genodermatosis? Marisa Grace 009* CCL17 attenuates tumor immunity by increasing regulatory T cells and China.Richard Antaya, Jennifer McNiff, Jing Zhou, Richard P. Lifton, Deepak Grace Ponzo, Margot Van Allen, Magdalena Martinka and Jan Peter Dutz. Th2 cells while decreasing myeloid-derived suppressor cells in tumor 024 ImmunomodulatoryNarayan and Keith A. effects Choate. ofNew nanoparticles Haven, CT. on the contact Vancouver, Canada. microenvironment. Makoto Sugaya, Sohshi Morimura, Tomonori Oka, 437* hypersensitivityGasdermin A3 targets response mitochondria in C57BL/6 to hairless mediate mice. keratinocyte Samreen Jatana necrosis, 450* Onychodystrophy, Palmoplantar keratoderma, and Amelogenesis Hiraku Suga, Tomomitsu Miyagaki, Yuichiro Tsunemi, Yoshihide Asano, Brianand skin C Palmer inflammation. and Lisa A Liang-Tung DeLouise. YangRochester,, Pei-Husan NY. Lin, Hsien-Yi Lin, Shu- imperfecta (OPA) syndrome caused by a homozygous mutation in 025 Capturing functional conservation between human skin and mouse DC Yayoi Tada, Takafumi Kadono and Shinichi Sato. Tokyo, Japan. Hui Wu and Cheng-Chin Kuo. Zhunan, Taiwan and Taichung, Taiwan. CNBD2. YC Metzger, O Sarig, R Bochner, D. Vodo, N Malchin, O Isakov, systems for generating better vaccines. Eynav Klechevsky. Saint Louis, 010 Distinctive downmodulation of plasmacytoid dendritic cell by vitamin 438 Genome wide association study of psoriasis in India. Rajan P Nair, Lam N Erez, A Gat, I Goldberg, N Shomron, M Schwartz, Irwin McLean, MO. D3 analogue in its interferon-α production and chemotactic activity. C. Tsoi, Manju Ghosh, Philip E. Stuart, Madhulika Kabra, Trilokraj Tejasvi, FJD Smith, FB Rihani and Eli Sprecher. Tel Aviv, Israel; Dundee, United 026* Human skin is protected by four functionally and phenotypically Takahiro Suzuki, Yoshiki Tokura. Hamamatsu, Japan. John J Voorhees, Goncalo Abecasis, Vinod Kumar Sharma and James T Kingdom; Salt Lake City, UT and Irbid, Jordan. discrete populations of resident and recirculating memory T cells. Rei 011** A wave of regulatory T cells into neonatal skin mediates tolerance to Elder. Ann Arbor, MI and New Delhi, India. 451* The BAF/SWI/SNF complex controls genome accessibility to p63 during Watanabe, Ahmed Gehad, Chao Yang, Laura Campbell, Jessica Emberley commensal microbes . Tiffany C Scharschmidt, Kimberly S Vasquez, Hong- 439 Cutaneous neovascularization in mice with chronic proliferative epidermal differentiation. Xiaomin Bao, Adam Rubin, Kun Qu, Jiajing Teague, Victor Huang, Tiago R Matos, Thomas S. Kupper and Rachael An Truong, Sofia V. Gearty, Mariela L Pauli, Audrey Nosbaum, Michael dermatitis (Sharpincpdm). Harm HogenEsch, Mario Sola, Timothy M Zhang, Paul Giresi, Howard Chang and Paul Khavari. Stanford, CA and Palo Clark. Boston, MA. Otto, James J Moon, Abul K. Abbas, Michael A Fischbach and Michael Stearns, Kathleen A Silva, Victoria E Kennedy, Lloyd E. King and John Paul Alto, CA. 027 Novel STAT3 inhibitor LLL12 significantly reduces IL-17, IL-22, and IFN- David Rosenblum. San Francisco, CA; Bethesda, MD and Charlestown, Sundberg. West Lafayette, IN; Bar Harbor, ME and Nashville, TN. 452* Novel regulatory variants identified in adult atopic dermatitis by gamma mRNA expression in psoriatic PBMCs. Justin G Hastings, Xiaoli MA. 440* Analysis of long non-coding RNAs highlights tissue-specific expression targeted deep sequencing alter enhancer function. Cristina de Guzman Zhang, Jiayuh Lin, Chenglong Li and Henry K Wong. Columbus, OH. 012 Keratin 17 enhances the chemotaxis of neutrophils through regulating patterns and epigenetic profiles in normal and psoriatic skin. James T Strong, Ashley Quiggle, Twinkal Marfatia, Kara Jill Gulewicz, Avner 028* GILT-mediated processing of a self and melanoma antigen in thymic chemokine CXCL1 secretion in keratinocytes via PI3k/AKT/NF-κB Elder, Lam C. Tsoi, Matthew K. Iyer, Philip E. Stuart, William R Swindell, Shemer, Zane Goodwin, Wendell Jones and Emma Guttman-Yassky. St. epithelial cells promotes deletion and regulatory T cells. Karen Taraszka pathway. Er-Le Dang, Liang Jin, Chang-xu Han, Bing Li, Man Jiang and Johann Eli Gudjonsson, Trilokraj Tejasvi, Mrinal Kumar Sarkar, Bingshan Louis, MO; Tel-Aviv, Israel and New York, NY. Hastings, Matthew Rausch, Todd C. Metzger, Michael Waterfield, Jessica Gang Wang. Xi’an, China. Li, Jun Ding, John J Voorhees, Hyun Min Kang, Rajan P Nair, Arul M Cortez and Mark S. Anderson. Phoenix, AZ and San Francisco, CA. 013* Contributions of skin resident and recirculating memory T cells to Chinnaiyan and Goncalo Abecasis. Ann Arbor, MI; Nashville, TN and depigmentation in vitiligo. Jillian Richmond, Mehdi Rashighi, Priti Bethesda, MD. Agarwal and John E Harris. Worcester, MA.

Notes: Notes:

89 1 16 PPosteroster P Presentationsresentations / /a abstractbstract t titlesitles

Adaptive453 Guanine Immunity nucleotide binding& Vaccination protein alpha q polypeptide (GnaqM1J): 014467 AcneEvidence vaccines for targetingcoordinate secretory regulation CAMP of factorHmga2 ofand Propionibacterium Tlr4 in hair follicle All orals [designatedAn ENU induced with an mutant asterisk allele (*)] affectinglisted below dermal are presented melanocytosis in the in the acnes.stem Chun-Ming cells. Yong HuangLi. Austin,. San Diego,MN. CA. Adaptive mouse.Immunity Christopher & Vaccination S Potter Minisymposium, Louise Dionne, on Heather Saturday, Fairfield, May 9, Soheil2015, S 015*468 IdentifyingMineralization Merkel of polyomavirus-specificsoft connective tissues CD4+ and and cartilage CD8+ T-cells in Enpp1asj-2Jin from 12:30-3:30Dadras, pm John in PaulSalon Sundberg D, Hilton and Atlanta. C. Herbert Orals designatedPratt. Farmington, by two asterisks CT and Bar Merkelmutant cell mice. carcinoma Jieyu Zhang patients’, Q. Li, tumor-infiltrating C. H Pratt, L A Dionne, lymphocytes. H Fairfield, Dafina S (**) will beHarbor, presented ME. during a Plenary Session. Orals designated by three IbraniY Karst,, Jayasri John G Paul Iyer, Sundberg Natalie Vandeven, and Jouni Natalie Uitto. Miller,Philadelphia, Olga Afanasiev, PA and Bar asterisks454 (***)Skin fragility will be presented of the wild-derived, during the inbredInterdisciplinary mouse strain Spotlight: Mus pahari. Skin DavidHarbor, Koelle ME. and Paul Nghiem. Seattle, WA. Cancer MinisymposiumThomas Sproule on, C.Friday, Herbert May Pratt, 8, 2015, Son from Yong 2:00 Karst, – 5:00Derry pm C Roopenianin the Grand and 016*469 RegulatoryMicroRNAs T cells involved facilitate in the cutaneous pathogenesis wound of healing.pachyonychia Audrey congenita. Nosbaum , Ballroom,John Hilton Paul Atlanta. Sundberg. Bar Harbor, ME. MonikaAndreas Ettinger, Berroth , Hong-AnYu-An Cao, Truong, Manuel Mariela A Flores, L Pauli, Tycho Sofia Speaker, V. Gearty, Mary AbulE K. 455 Mouse models of skin and adnexal diseases in the Mouse Mutant AbbasSchwartz, and Michael Christopher David Contag Rosenblum. and Roger San Francisco, Kaspar. Stanford, CA. CA; Santa Cruz, + + 001 RON2315:Resource A(MMR) novel humanat The Jackson biologic Laboratory. for the topical C. Herbert treatment Pratt of, Louisepsoriasis. 017 QuantificationCA and Salt Lake of City, CD69 UT.CD103 skin TRM cells in chronic atopic dermatitis. ThomasDionne, Gadek Laura. GPortola Reinholdt, Valley, David CA. E Bergstrom, Heather Fairfield, Belinda 470 SeoHyeongIdentification KIM, Chang of MITF Ook regulatedPark, Jung microRNAsU Shin, Ji Yeon in melanoma.Noh, Shan Ashika Jin, 002* BlockadeS Harris, forSon CD155-TIGIT Yong Karst and interaction John Paul is Sundberg. an effective Bar Harbor, therapy ME. for HeminJayanthy Lee,, VijayasaradhiJungsoo Lee, ThomasSetaluri. S. Madison, Kupper and WI. Kwang Hoon Lee. Seoul, 456 melanoma.Inherited LCK Takashi deficiency Inozume causes, Tomonori susceptibility Yaguchi, Yutaka to EV-HPV Kawakami infections and Korea (the Republic of) and Boston, MA. Shinjiand early-onsetShimada. Chuo, squamous Japan and cell Shinjyuku,carcinoma. Japan. Shuli Li, Lina Duo, Huijun 018* Shared VH1-46 antibody gene usage in pemphigus vulgaris predicts 003 MigratoryWang, Wei DC Dai, temper Weigang subcutaneous Zhang, Eray immunity Yihui Zhou, through Xu Cao, key Jiahui tolerance Zhao, Sen antibody cross-reactivity to desmoglein 3 and rotavirus VP6. Michael pathways.Guo, Yanan Niroshana Xu, Tao Zhao, Anandasabapathy Yueyuan Xiao,, Christopher Cuiling Ma, Nirschl, Li Xia, Zhihua Yong Liu, Yang, GrowthJeffrey Factors, Tejada Cho, ChristophCell Adhesion, Ellebrecht, Christoph & Matrix Matthias Biology Hammers, ShamimLiangtao Mollah, Zheng, Rachel Yiyao Hu,E. Feder, Cheng Pinru Feng, Wu, Jinghua Peter Yin,Sage Guiwen and Arlene Xu, Zhimiao H All oralsGopal [designated Sapparapu, with James an asterisk Crowe (*)]and listed Aimee below S Payne. are Philadelphia,presented in thePA and Sharpe.Lin, Tianwen Boston, Gao, MA Yong and NewYang York, and ChunyingNY. Li. Xi’an, China; Beijing, China GrowthNashville, Factors, TN.Cell Adhesion, & Matrix Biology Minisymposium on Saturday, 004 Rationaleand Yinchuan, and designChina. of a novel dendritic cell targeted vaccine for basal 019*May 9,Next 2015, generation from 12:30-3:30 T cell receptor pm in Salon sequencing AB, Hilton reveals Atlanta. complex Orals designatedT cell by 457 cellIntra-familial carcinoma. variation Karyn Haitz in, Stevenclinical Rphenotype Barthel, Yong of CARD14 Liu, Christopher-related two asterisksdynamics (**) in willAlopecia be presented Areata . duringAnnemieke a Plenary de Jong Session., Luzhou Orals Xing, designated Ali by Nirschl,psoriasis. Ervin Marina Epstein Eskin-Schwartz and Niroshana, Lina Anandasabapathy. Basel-Vanagaite, Boston, Michael MA David, and three asterisksJabbari, Zhenpeng (***) will Dai,be presented Vera H Price, during Madeleine the Interdisciplinary Duvic, David Norris,Spotlight: Skin Oakland,Irina Lagovsky, CA. Dan Ben-Amitay, Pola Smirin-Yosef, Lihi Atzmony and CancerMaria Minisymposium Hordinsky, Julian on Friday, Mackay-Wiggan, May 8, 2015, Raphael from 2:00 Clynes – 5:00 and pm Angela in the Grand 005 AnEmmilia ex vivo Hodak. skin model Petah that Tikva, combines Israel and topical Tel Aviv, skin Israel. penetration and Th17 Ballroom,Christiano. Hilton Atlanta. New York, NY; San Francisco, CA; Houston, TX; Denver, CO and 458 stimulation.Mutations Maryaffecting Bedard keratin, Steven 10Cook, surface Leandro exposed Santos, residues Jessica highlight Neil, the Minneapolis, MN. Carlosstructural Eduardo basis Peredo, of phenotypic Susan H Smith,variation Javier in Cote-Sierraepidermolytic and ichthyosis.Jon Lenn. 020471 CalcitoninSubcutaneous gene-related adipose peptide tissue (CGRP)accumulation induces endothelialmediated by cellslymphatic (EC) to ResearchHaris Mirza Triangle, Anil Park,Kumar, NC. Brittany Craiglow, Jing Zhou, Corey Saraceni, biasdysfunction. Langerhans Kentaro cell (LC) Kajiya antigen, Mika presentation Sawane and Nobuyukitowards a Takakura.Th17 response Bruce Ragsdale, Leonard Milstone, Paul Rehder, Annamari Ranki and throughYokohama, induction Japan andof soluble Suita, Japan.mediators. Wanhong Ding, Lori L Stohl, 006 Immunomodulatory effects of AM1030, a topical 5-HT2B receptor antagonistKeith A. Choate. in development New Haven, for CT; atopic Zurich, dermatitis. Switzerland; Niklas San Palmqvist Luis Obispo,, Max CA; 472 JohnSmurfs A Wagner, E3 ubiquitin Linghui ligasesXu and Richardnegatively David regulate Granstein. TGF-β Newsignaling York, inNY. Siller,Oxnard, Anders CA andSjödin, Helsinki, Helena Finland. Arozenius, Christina Wenglén, Anna-Carin 021* Elevatedkeratinocytes. thymic stromalKen Shiraishi lymphopoietin, Xiuju Dai, Masamotoexpression Murakami,in the skin Mikikoblocks 459 Ryde,Systems Lars biologicalPettersson, analysis Cecilia ofKlint, alopecia Anna areataPramhed, reveals Anna master Löfdahl regulators and breastTohyama, carcinogenesis. Natsuki Matsushita, Shadmehr Takeshi Demehri Imamura, Trevor andJ Cunningham, Koji Sayama. Sindhu Toon, Gunillaof hair Ekström. follicle immune Lund, Sweden. privilege. James Chen, Ali Jabbari, Jane E Cerise Manivasagam,Japan. Melissa Meyer, David Denardo, Raphael Kopan and Wayne 007 Phenotypicand Angela analysis Christiano. of dendritic New York, cells NY. infiltrating a spontaneous model 473* Yokoyama.EphA2 negatively St. Louis, MOregulates and Cincinnati, EGFR to promote OH. keratinocyte 460 ofA basal role forcell autocrine carcinoma. and Christopher paracrine Nirschlaction, Yongof the Liu, Th1 Pinru chemokines Wu, Karyn in the 022 Topicaldifferentiation. application Bethany of eupatilin Elena Perez ameliorates White, Paulatopic Thomas, dermatitis-like Joshua skin Haitzpathogenesis and Niroshana of keratoderma. Anandasabapathy. Christina Boston, Young MA., Ellen Rorke and Richard lesionsRappoport of NC/Nga and Spiro mice. Getsios. Young MinChicago, Park, IL.Ji Hyun Lee, Ye Jin Lee and Jun 008 PotentialEckert. Baltimore, mechanisms MD. for loss of hair follicle immune privilege in 474**young Integrin Lee. α Seoul,v is necessary Korea (the for Republic skin tissue of). generation and SCC tumor + 461 patientsPathway withanalysis alopecia and protein-proteinareata following interaction hepatitis Bnetwork vaccination. construction 023 CD8invasion,αα T cells but contribute is dispensable to lichen for epidermal planus independence maintenance. of Elizabeth LAMP1- Christopherprovide functional Richardson interpretation, Elaine Gilmore of and GWAS Brian evidence Poligone. in Rochester,alopecia areata. NY. meditatedKennedy degranulation.Duperret, Todd BingWilliam Li, Xiuwen Ridky. Philadelphia,Sun and Gang PA. Wang. Xi’an, 009* CCL17L. Petukhova attenuates, Angela tumor Christiano. immunity Newby increasing York, NY. regulatory T cells and 475* China.Desmosomal mediated mechanotransduction regulates cell adhesion 462 Th2Juxta-articular cells while decreasing joint-capsule myeloid-derived mineralization suppressor in CD73 cellsdeficient in tumor mice: 024 Immunomodulatoryand signaling. Joshua effects A Broussard of nanoparticles, Kathleen J Green.on the contactChicago, IL. microenvironment.Similarities to patients Makoto with Sugaya NT5E, mutations.Sohshi Morimura, Dian Wang Tomonori, Q. Li, Oka, Thea 476 hypersensitivityTailoring fibroblast response culture in C57BL/6media to hairlessbroaden mice. functionality Samreen Jatana and , HirakuP Price, Suga, John Tomomitsu Paul Sundberg Miyagaki, and Jouni Yuichiro Uitto. Tsunemi, Philadelphia, Yoshihide PA Asano,and Bar Brianincrease C Palmer cytokine and Lisa responsiveness. A DeLouise. Rochester, Peter Girling NY., Baertschi Stefan and YayoiHarbor, Tada, ME. Takafumi Kadono and Shinichi Sato. Tokyo, Japan. 025 CapturingChennakesava functional Cuddapah. conservation Bern, Switzerland. between human skin and mouse DC 010463 DistinctivemiR29b1 plays downmodulation an important role of plasmacytoidin epidermal celldendritic growth cell and by survival vitamin . 477 systemsEstrogen for receptor generating alpha-mediated better vaccines. control Eynav of Klechevsky growth factor. Saint production Louis, D3Xiaoling analogue Zhang in its, Joseph interferon- Wu, Jeanα production Qin and Jennifer and chemotactic Y Zhang. Durham, activity. NC. MO.from nipple fibroblasts. Hsin-Jung Wu, Dan F Spandau, Sunil S. Tholpady, 464 TakahiroKindler Suzukisyndrome:, Yoshiki Novel Tokura. and Hamamatsu,recurrent FERMT1 Japan. mutations in 20 unique 026* HumanCarlos skin Offutt, is protected Sachiko by Koyama four functionally and John G. andFoley. phenotypically Bloomington, IN and 011** Afamilies wave of with regulatory 70 patients T cells andinto evidenceneonatal skinof genetic mediates heterogeneity. tolerance toLeila discreteIndianapolis, populations IN. of resident and recirculating memory T cells. Rei commensalYoussefian ,microbes Hassan Vahidnezhad, . Tiffany C Scharschmidt Mohammad, Kimberly R Barzegar, S Vasquez, Q. Li, S Zeinali, Hong- 478 WatanabeDefining, Ahmedmechanisms Gehad, that Chao regulate Yang, Laura dermal Campbell, adipose Jessicatissue Emberleyin the skin. AnP Mansouri,Truong, Sofia M R V. Basiri Gearty, and MarielaJouni Uitto. L Pauli, Tehran, Audrey Iran Nosbaum, (the Islamic Michael Republic Teague,Guillermo Victor Rivera Huang, Gonzalez Tiago R, Valerie Matos, Horsley. Thomas NewS. Kupper Haven, and CT. Rachael Otto,of) and James Philadelphia, J Moon, AbulPA. K. Abbas, Michael A Fischbach and Michael 479* Clark.Altered Boston, desmosome MA. organization, endocytosis and desmosome splitting 465 DavidSomatic Rosenblum. V600E BRAF San Francisco,mutation CA; causes Bethesda, syringocystadenoma MD and Charlestown, papilliferum. 027 Novelin pemphigus STAT3 inhibitor vulgaris LLL12 epidermis significantly as revealed reduces by IL-17, super-resolution IL-22, and IFN- MA.Jonathan Levinsohn, Jeffrey Sugarman, Kaya Bilguvar, Jennifer McNiff and gammamicroscopy. mRNA Saraexpression N Stahley in ,psoriatic Maxine Warren, PBMCs. JustinRon J Feldman, G Hastings Robert, Xiaoli 012 KeratinKeith A. 17 Choate. enhances New the Haven, chemotaxis CT and Sanof neutrophils Francisco, CA.through regulating Zhang,Swerlick, Jiayuh Alexa Lin, Mattheyses Chenglong Li andand AndrewHenry K Kowalczyk.Wong. Columbus, Atlanta, OH. GA. 466 chemokineThe spectrum CXCL1 of secretionCOL7A1 mutations in keratinocytes identified via PI3k/AKT/NF-in 63 familiesκB with 028*480* GILT-mediatedExclusion of insulinprocessing and ofIGF-1 a self receptors and melanoma from caveolar antigen domains in thymic by epithelial cells promotes deletion and regulatory T cells. Karen Taraszka pathway.dystrophic Er-Le epidermolysis Dang, Liang Jin,bullosa Chang-xu by comparative Han, Bing Li, Sanger Man Jiang and andnext ganglioside GM3 mediates insulin resistance. Duncan Hieu M Dam, June Hastings, Matthew Rausch, Todd C. Metzger, Michael Waterfield, Jessica Ganggeneration Wang. Xi’an, sequencing. China. Hassan Vahidnezhad, Leila Youssefian, S Zeinali, Jung ha Park, Betty Kong, Xiao-Qi Wang and Amy S. Paller. Chicago, IL. Cortez and Mark S. Anderson. Phoenix, AZ and San Francisco, CA. 013* ContributionsMohammad R ofBarzegar, skin resident Soheila and Sotoudeh, recirculating Adam Ertel,memory Q. TLi, cells Nikoo to depigmentationMozaffari, Paolo in Fortinavitiligo. Jillianand Jouni Richmond Uitto., MehdiTehran, Rashighi, Iran (the PritiIslamic Republic Agarwalof) and and Philadelphia, John E Harris. PA. Worcester, MA.

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1 17 90 PPosteroster P Presentationsresentations // aabstractbstract ttitlesitles

Adaptive Immunity & Vaccination 481014 BeneficialAcne vaccines effects targeting of blood secretory group antigenCAMP factor synthesis-increasing of Propionibacterium molecules 495 Topical solenopsin analogs improve inflammation and acanthosis in All orals [designated with an asterisk (*)] listed below are presented in the onacnes. extracellular Chun-Ming matrix Huang protein. San Diego, production CA. in vivo. Min Kyeong Shin, Mira the KC-Tie2 mouse model of psoriasis. Jack Leonard Arbiser, Kellie A Adaptive Immunity & Vaccination Minisymposium on Saturday, May 9, 2015, 015* Choi,Identifying Jang-Hee Merkel Oh, Se-Rah polyomavirus-specific Lee, Dong Hun Lee, CD4+ Seon-PIL and CD8+ Jin, Min-KyoungT-cells in Michaels, Ronald S Nowak, Michael Bonner, Isabella Karlsson, Yi Fritz and from 12:30-3:30 pm in Salon D, Hilton Atlanta. Orals designated by two asterisks Kim,Merkel Soyun cell Chocarcinoma and Jin-Ho patients’ Chung. tumor-infiltrating Seoul, Korea (the Republic lymphocytes. of). Dafina Nicole L Ward. Atlanta, GA and Cleveland, OH. (**) will be presented during a Plenary Session. Orals designated by three 482 UVIbrani irradiation-induced, Jayasri G Iyer, Natalie production Vandeven, of Natalie monoglycosylated Miller, Olga Afanasiev,biglycan 496* Role of integrin-linked kinase in keratinocyte survival. Lina Dagnino, asterisks (***) will be presented during the Interdisciplinary Spotlight: Skin throughDavid Koelle downregulation and Paul Nghiem. of xylosyltransferase Seattle, WA. 1 in cultured human Michelle Im. London, Canada. EDA Cancer Minisymposium on Friday, May 8, 2015, from 2:00 – 5:00 pm in the Grand 016* dermalRegulatory fibroblasts. T cells facilitate Mira Han cutaneous, Cheng Long wound Jin, Jang-Hee healing. AudreyOh, Cheng Nosbaum Yao, , 497 Intra-abdominal adhesions: Potential pathogenic role of fibronectin + Ballroom, Hilton Atlanta. Chi-HyunMonika Ettinger, Park, Zhe HuHong-An Jin and Truong, Jin-Ho Chung.Mariela LSeoul, Pauli, KoreaSofia (theV. Gearty,Republic Abul K. and Gli1 cells. Christine F Lotto, Edward Macarak, X Jin, E Rosato, Jouni of)Abbas and and Yanji, Michael China. David Rosenblum. San Francisco, CA. Uitto and Joel Rosenbloom. Philadelphia, PA. + + 001 RON2315: A novel human biologic for the topical treatment of psoriasis. 483017 AnalysisQuantification of glycosaminoglycan of CD69 CD103 composition skin TRM cells inchange chronic in intrinsicallyatopic dermatitis. aged 498 Matrilin-2 and ADAMTS-4 express in aggressive basal cell carcinomas Thomas Gadek. Portola Valley, CA. andSeoHyeong photoaged KIM human, Chang skinOok inPark, vivo. Jung Yeon U Shin,Kyung Ji KimYeon, Jang-Hee Noh, Shan Oh, Jin, Dayae and regulate basal cell carcinomas progression. Zhengke Wang, Fang 002* Blockade for CD155-TIGIT interaction is an effective therapy for Lee,Hemin Min Lee, Kyeong Jungsoo Shin, Lee, Kyu Thomas Han Kim S. and Kupper Jin-Ho and Chung. Kwang Seoul, Hoon KoreaLee. Seoul, (the Xiong, Ming Lu, Catherine Breen and Satori Iwamoto. Providence, RI. melanoma. Takashi Inozume, Tomonori Yaguchi, Yutaka Kawakami and RepublicKorea (the of). Republic of) and Boston, MA. 499 Anti-ageing clinical efficacy of stabilized retinol is associated with the Shinji Shimada. Chuo, Japan and Shinjyuku, Japan. 484*018* TGFSharedβ release VH1-46 by antibody fibroblasts gene requires usage regulatedin pemphigus secretion vulgaris via predicts stimulation of hyaluronic acid production. Ramine Parsa, HK Helene 003 Migratory DC temper subcutaneous immunity through key tolerance autophagosomes.antibody cross-reactivity Beate Eckes to , desmogleinJulian Nuechel, 3 and Katrin rotavirus Blumbach, VP6. Michael Katrin Wong, Yaping Hu, Simarna Kaur, Manpreet Randhawa and Michael pathways. Niroshana Anandasabapathy, Christopher Nirschl, Yong Liu, Schoenborn,Jeffrey Tejada Jan-Niklas Cho, Christoph Schulz, Ellebrecht, Alexandra Christoph Zuk, Gerhard Matthias Sengle, Hammers, Georg Southall. Skillman, NJ. Shamim Mollah, Rachel E. Feder, Pinru Wu, Peter Sage and Arlene H Brunner,Gopal Sapparapu, Thomas Krieg James and Crowe Markus and Plomann. Aimee S Payne. Cologne, Philadelphia, Germany and PA and 500 Secreted heat shock protein-90 alpha (Hsp90α) is essential for skin Sharpe. Boston, MA and New York, NY. Muenster,Nashville, TN.Germany. wound healing. Ayesha Bhatia, Kathryn O’Brien, Takashi Imai, Mei Chen, 004 Rationale and design of a novel dendritic cell targeted vaccine for basal 485019* DeglycationNext generation activity T cell of receptor a combination sequencing of Salvia reveals miltiorrhiza complex extract T cell and David Timothy Woodley, Heiichiro Udono and Wei Li. Los Angeles, CA and cell carcinoma. Karyn Haitz, Steven R Barthel, Yong Liu, Christopher Niacin.dynamics Sabrina in Alopecia Leoty-Okombi Areata ,. JulieAnnemieke Saget, Aureliede Jong Boher,, Luzhou Amandine Xing, Ali Chiba, Japan. Nirschl, Ervin Epstein and Niroshana Anandasabapathy. Boston, MA and Gaydon,Jabbari, ZhenpengOlga Freis andDai, ValerieVera H Price,Andre-Frei. Madeleine Lyon, Duvic,France. David Norris, 501 Increased circulating monocyte aggregates in psoriasis patients exhibit Oakland, CA. 486* LysylMaria hydroxylase Hordinsky, Julian3 localizes Mackay-Wiggan, to epidermal Raphael basement Clynes membrane and Angela and is an adhesion profile distinct from classical monocytes . Jackelyn B 005 An ex vivo skin model that combines topical skin penetration and Th17 reducedChristiano. in patients New York, with NY; recessiveSan Francisco, dystrophic CA; Houston, epidermolysis TX; Denver, bullosa. CO and Golden, Sarah G Groft, Michael V Squeri, Thomas McCormick and Kevin D stimulation. Mary Bedard, Steven Cook, Leandro Santos, Jessica Neil, StephenMinneapolis, Watt ,MN. Jasbani Dayal, Sheila Wright, Celine Pourreyron, James Cooper. Cleveland, OH. Carlos Eduardo Peredo, Susan H Smith, Javier Cote-Sierra and Jon Lenn. 020 McMillan,Calcitonin Megangene-related Riddle, peptide Irwin McLean, (CGRP) Irene induces Leigh, endothelial John McGrath, cells (EC) Julio to 502*** Fibulin-4 is down-regulated in malignant head and neck SCC. Kathleen P Research Triangle Park, NC. Salas-Alanis,bias Langerhans Jakub cell Tolar (LC) and antigen Andrew presentation P South. Dundee, towards United a Th17 Kingdom; response McGuinn, Takako Sasaki, Mon Li Chu and My G Mahoney. Philadelphia, PA London,through Unitedinduction Kingdom; of soluble Minneapolis, mediators. MN; Wanhong Monterrey, Ding ,Mexico Lori L Stohl, and and Oita, Japan. 006 Immunomodulatory effects of AM1030, a topical 5-HT2B receptor antagonist in development for atopic dermatitis. Niklas Palmqvist, Max Philadelphia,John A Wagner, PA. Linghui Xu and Richard David Granstein. New York, NY. Siller, Anders Sjödin, Helena Arozenius, Christina Wenglén, Anna-Carin 487021* Self-deliveringElevated thymic RNAi stromal compounds lymphopoietin targeting expression collagenase in the1. Katherine skin blocks Ryde, Lars Pettersson, Cecilia Klint, Anna Pramhed, Anna Löfdahl and Holtonbreast, carcinogenesis. Melissa Maxwell, Shadmehr James Cardia, Demehri Lakshmipathi, Trevor J Cunningham, Pandarinathan Sindhu and Gunilla Ekström. Lund, Sweden. KarenManivasagam, Bulock. Marlborough, Melissa Meyer, MA. David Denardo, Raphael Kopan and Wayne Innate Immunity, Inflammation & Microbiology 007 Phenotypic analysis of dendritic cells infiltrating a spontaneous model 488* PalmitoylationYokoyama. St. Louis, of the MO desmosomal and Cincinnati, cadherins OH. is important for protein All orals [designated with an asterisk (*)] listed below are presented in the of basal cell carcinoma. Christopher Nirschl, Yong Liu, Pinru Wu, Karyn 022 stabilityTopical application and assembly of dynamics.eupatilin Brettameliorates J Roberts atopic, Robert dermatitis-like Svoboda, Keith skin Innate Immunity, Inflammation & Microbiology Minisymposium on Friday, May Haitz and Niroshana Anandasabapathy. Boston, MA. Johnsonlesions of and NC/Nga James mice. K Wahl. Young Lincoln, Min NE.Park, Ji Hyun Lee, Ye Jin Lee and Jun 8, 2015, from 2:00-5:00 pm in Salon E, Hilton Atlanta. Orals designated by two 008 Potential mechanisms for loss of hair follicle immune privilege in 489*** Differentialyoung Lee. Seoul, requirement Korea (the for Republic HB-EGF of).vs. amphiregulin for survival of asterisks (**) will be presented during a Plenary Session. Orals designated by + patients with alopecia areata following hepatitis B vaccination. 023 malignantCD8αα T cellsvs. normal contribute epithelial to lichen cells. planus Stefan independence W Stoll, James of T LAMP1-Elder. Ann three asterisks (***) will be presented during the Interdisciplinary Spotlight: Skin Christopher Richardson, Elaine Gilmore and Brian Poligone. Rochester, NY. Arbor,meditated MI. degranulation. Bing Li, Xiuwen Sun and Gang Wang. Xi’an, Cancer Minisymposium on Friday, May 8, 2015, from 2:00 – 5:00 pm in the Grand 009* CCL17 attenuates tumor immunity by increasing regulatory T cells and 490* RDEBChina. fibroblast-derived periostin promotes the invasion of squamous Ballroom, Hilton Atlanta. Th2 cells while decreasing myeloid-derived suppressor cells in tumor 024 cellImmunomodulatory carcinoma . Mei Chen effects, Xinyi of Wang,nanoparticles Yingping onHou, the Jon contact Cogan, Olivia microenvironment. Makoto Sugaya, Sohshi Morimura, Tomonori Oka, Lai,hypersensitivity Weihuang Ning response and David in TimothyC57BL/6 Woodley.hairless mice.Los SamreenAngeles, CA.Jatana, 503 Trichodysplasia spinulosa-associated polyomavirus small T antigen Hiraku Suga, Tomomitsu Miyagaki, Yuichiro Tsunemi, Yoshihide Asano, 491* RapamycinBrian C Palmer modulates and Lisa the A DeLouise. glucocorticoid Rochester, receptor NY. functions, blocks activates MAPK pathway. Julie H Wu, Harrison Nguyen, Rebecca Yayoi Tada, Takafumi Kadono and Shinichi Sato. Tokyo, Japan. 025 atrophogeneCapturing functional REDD1 expression, conservation and protectsbetween skinhuman against skin steroid-and mouse DC Simonette, Peter L Rady and Stephen K Tyring. Houston, TX. 010 Distinctive downmodulation of plasmacytoid dendritic cell by vitamin inducedsystems atrophyfor generating . Irina Budunova better vaccines., Ekaterina Eynav Lesovaya, Klechevsky Elena. Saint Vinokour, Louis, 504 Recognition of melanoma by an innate immune receptor Dectin-1 D3 analogue in its interferon-α production and chemotactic activity. GlebMO. Baida, Pankaj Bhalla, Kirill Kirsanov, Marianna Yakubovskaya, orchestrates innate immune cells for anti-tumor responses. Hiroaki Takahiro Suzuki, Yoshiki Tokura. Hamamatsu, Japan. 026* LeonidasHuman skin Platanias, is protected Ben Readhead by four functionally and Joel Dudley. and Chicago,phenotypically IL; Moscow, Ikushima. Tokyo, Japan. 011** A wave of regulatory T cells into neonatal skin mediates tolerance to Russiandiscrete Federation populations and of residentNew York, and NY. recirculating memory T cells. Rei 505 Use of a translational human ex-vivo skin model to predict clinical commensal microbes . Tiffany C Scharschmidt, Kimberly S Vasquez, Hong- 492 ReducedWatanabe mechanical, Ahmed Gehad, force Chaosuppresses Yang, Lauraextracellular Campbell, matrix Jessica production Emberley effective dose of a topical drug candidate. Jessica Neil, Jean-Marie Brusq, An Truong, Sofia V. Gearty, Mariela L Pauli, Audrey Nosbaum, Michael viaTeague, specific Victor down-regulation Huang, Tiago R Matos, of TGF-β Thomastype II receptor S. Kupper in and adult Rachael human Carlos Eduardo Peredo, Susan H Smith, Beth Millerman, Leandro Santos, Otto, James J Moon, Abul K. Abbas, Michael A Fischbach and Michael dermalClark. Boston, fibroblasts: MA. Implications for the role of mechanobiology in Mary Bedard, Fabrice Viviani and Javier Cote-Sierra. Research Triangle David Rosenblum. San Francisco, CA; Bethesda, MD and Charlestown, 027 skinNovel aging. STAT3 Taihao inhibitor Quan LLL12, Zhaoping significantly Qin, Yuan reduces Shao, IL-17,Tianyuan IL-22, He, and John IFN- J Park, NC and Les Ulis, France. MA. Voorheesgamma mRNA and Gary expression J Fisher. in Ann psoriatic Arbor, MI.PBMCs. Justin G Hastings, Xiaoli 506 GSK compound A Inhibits keratinocyte and T lymphocyte proliferation 012 Keratin 17 enhances the chemotaxis of neutrophils through regulating 493* OxidativeZhang, Jiayuh stress Lin, reduces Chenglong collagen Li and productionHenry K Wong. through Columbus, eIF2α-dependent OH. and cytokine production by blocking cell cycle progression at the G1-S chemokine CXCL1 secretion in keratinocytes via PI3k/AKT/NF-κB 028* down-regulationGILT-mediated processing of transforming of a self growthand melanoma factor-beta antigen signaling in thymic pathway transition phase Thi Bui, Christine Coquery, David Rickard, John Moore, pathway. Er-Le Dang, Liang Jin, Chang-xu Han, Bing Li, Man Jiang and inepithelial human dermalcells promotes fibroblasts. deletion Tianyuan and Heregulatory, Taihao Quan,T cells. JohnKaren J VoorheesTaraszka Susan H Smith and Javier Cote-Sierra. Research Triangle Park, NC. Gang Wang. Xi’an, China. andHastings Gary, JMatthew Fisher. Ann Rausch, Arbor, ToddMI. C. Metzger, Michael Waterfield, Jessica 507 AN2728, a new boron-based topical anti-inflammatory agent, inhibits 013* Contributions of skin resident and recirculating memory T cells to 494* TheCortez role and of theMark hemidesmosomal S. Anderson. Phoenix, protein AZ BP180and San in Francisco, granulopoiesis. CA. Lin phosphodiesterase 4 (PDE4). Yvonne Freund, Chen Dong, Charlotte depigmentation in vitiligo. Jillian Richmond, Mehdi Rashighi, Priti Lin, Bin-Jin Hwang, Ning Li, Luis A. Diaz and Zhi Liu. Chapel Hill, NC. Virtucio-Frates, Fernando Rock, Yvonne Mak, Yasheen Zhou, Lee Zane and Agarwal and John E Harris. Worcester, MA. Kurt Jarnagin. Palo Alto, CA.

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91 1 18 PPosteroster P Presentationsresentations / /a abstractbstract t titlesitles

Adaptive508* Dysbiotic Immunity microbiota drives& Vaccination atopic inflammation in Adam17fl/flSox9-Cre 014524* AcneTLR4 vaccines acts as targetinga death receptor secretory for CAMPultraviolet factor radiation of Propionibacterium (UVR) in antigen All orals [designatedmice. Tetsuro with Kobayashi an asterisk, Martin (*)] listed Glatz, below Keisuke are presentedHoriuchi, Thomas in the Doebel, acnes.presenting Chun-Ming cells. HuangHua Zhou. San, ErinDiego, Harberts, CA. Rita Fishelevich, Stefanie Vogel AdaptiveDaniel Immunity Kaplan, & Vaccination Heidi H Kong, Minisymposium Masayuki Amagai on Saturday,and Keisuke May Nagao. 9, 2015, Tokyo, 015* Identifyingand Anthony Merkel Gaspari. polyomavirus-specific Baltimore, MD. CD4+ and CD8+ T-cells in from 12:30-3:30Japan; Bethesda,pm in Salon MD D, and Hilton Minneapolis, Atlanta. Orals MN. designated by two asterisks 525 MerkelReal-time cell carcinoma imaging ofpatients’ Bartonella tumor-infiltrating henselae invading maturelymphocytes. human Dafina (**)509* will beIL-1 presentedβ-independent during neutrophila Plenary Session. recruitment Orals inducesdesignated long-term by three protection Ibranierythrocytes., Jayasri G Iyer,Marna Natalie Ericson Vandeven,, Gislaine Natalie Viera-Damiani, Miller, Olga Marlene Afanasiev, Neves da asterisks (***)against will a beStaphylococcus presented during aureus the skin Interdisciplinary reinfection. Carly Spotlight: Page ,Skin Da Lee, DavidSilva, Koelle Kalpna and Gupta, Paul Nghiem.Tania Soares, Seattle, Maria WA. Cintra, Amanda de Almeida, Vitor Cancer MinisymposiumYu Wang, Jonathan on Friday, Shahbazian, May 8, Alyssa2015, fromAshbaugh 2:00 – and 5:00 Lloyd pm inS Miller.the Grand 016* RegulatoryPelegati, TAndre cells facilitatede Thomaz, cutaneous Mariana woundBaratti, healing. Hernandes Audrey Carvalho, Nosbaum Carlos, Ballroom,Baltimore, Hilton Atlanta. MD. MonikaLenz Cesar Ettinger, and Paulo Hong-An Velho. Truong, Minneapolis, Mariela LMN; Pauli, Campinas, Sofia V. Brazil Gearty, and Abul Sao K. 510 Role of filaggrin-deficiency, skin injury and Staphylococcus aureus in AbbasPaulo, and Brazil. Michael David Rosenblum. San Francisco, CA. + + 001 RON2315:atopic dermatitis-like A novel human skin biologic inflammation for the topical in mice.treatment Nate Archer of ,psoriasis. Yu Wang, 017526* QuantificationAngiogenic peptide-30 of CD69 CD103 (AG-30) skin activates TRM cells inprimary chronic human atopic keratinocytesdermatitis. ThomasRoger Ortines, Gadek. Portola Alyssa Valley,Ashbaugh, CA. Carly Page, Michiko Oyoshi, Raif Geha SeoHyeongto produce KIM cytokines/chemokines, Chang Ook Park, Jung via U MrgXShin, Jireceptors. Yeon Noh, Chanisa Shan Jin, 002* Blockadeand Lloyd for S Miller.CD155-TIGIT Baltimore, interaction MD and is Boston,an effective MA. therapy for HeminKiatsurayanon Lee, Jungsoo, Francois Lee, Thomas Niyonsaba, S. Kupper Hiroko and Ushio, Kwang Shigaku Hoon Ikeda, Lee. Seoul, Ko 511 melanoma.Integration Takashi of IL17 Inozume and TNF, Tomonori responses Yaguchi, in human Yutaka keratinocytes. Kawakami Sitharamand KoreaOkumura (the Republic and Hideoki of) and Ogawa. Boston, Tokyo, MA. Japan. ShinjiRamaswami Shimada., Mary Chuo, E JapanAnderson and andShinjyuku, Matthew Japan. S Hayden. New York, NY. 018*527 SharedIdentification VH1-46 antibody and modulation gene usage of in cytokinespemphigus produced vulgaris predictsfrom skin-derived 003512 MigratoryExpression DC of temper toll like subcutaneous receptors 3, 7,immunity 8, and 9 throughin peripheral key tolerance blood antibodyinnate lymphoid cross-reactivity cells. Christine to desmoglein Coquery 3, Thiand Bui, rotavirus Susan HVP6. Smith Michael and pathways.mononuclear Niroshana cells from Anandasabapathy patients with, Christopherpsoriasis . Hee Nirschl, Joo Kim Yong, Sung Liu, Hee JeffreyJavier TejadaCote-Sierra. Cho, Christoph Research Ellebrecht, Triangle Parl, Christoph NC. Matthias Hammers, ShamimKim, Jeong Mollah, Hwan Rachel Je, Dae E. Feder,Suk Kim, Pinru Dong Wu, Youn Peter Shin Sage and and Min-Geol Arlene HLee. 528 GopalRole Sapparapu, of galectin-7 James in pathogenesis Crowe and Aimee of psoriasis: S Payne. regulation Philadelphia, of PAskin and Sharpe.Seoul, KoreaBoston, (the MA Republic and New of). York, NY. Nashville,inflammation TN. and epidermal homeostasis through two microRNA 004513 RationaleBacteria inand the design human of skina novel microbiome dendritic mediate cell targeted glycerol vaccine fermentation for basal 019* Nextpathways. generation Hung-Lin T cell Chen receptor, Chia-Hui sequencing Lo, Meng-Ping reveals Lu,complex Yuan-Hsin T cell Lo, cellagainst carcinoma. Malassezia Karyn furfur. Haitz, Ming-ShanSteven R Barthel, Kao, Ying-Hsien Yong Liu, ChristopherLee, Yanhan Wang, dynamicsHuan-Yuan in Alopecia Chen and Areata Fu-Tong . Annemieke Liu. Taipei, de Taiwan Jong ,and Luzhou Davis, Xing, CA. Ali Nirschl,Richard Ervin L Gallo Epstein and Chun-Mingand Niroshana Huang. Anandasabapathy. Taoyuan, Taiwan Boston, and San MA Diego, and 529 Jabbari,SIG1273: Zhenpeng A skin protectingDai, Vera H Price,cosmetic Madeleine functional Duvic, ingredient David Norris, with a Oakland,CA. CA. Mariabroad Hordinsky, spectrum Julian of anti-aging Mackay-Wiggan, and anti-inflammatory Raphael Clynes and properties. Angela Jose 005514 AnUnprocessed ex vivo skin IL-36modelα regulatesthat combines psoriasis-like topical skin skin penetration inflammation and inTh17 co- Christiano.R Fernandez New, Karl York, Rouzard, NY; San Michael Francisco, Voronkov, CA; Houston, Kristen TX; L. Huber,Denver, Corey CO and stimulation.operation Marywith IL-1 Bedardα Liselotte, Steven Jensen Cook,, HangfeiLeandro Fu, Santos, Katelynn Jessica A Milora Neil, and Minneapolis,Webb, Maxwell MN. Stock, Jeffry B. Stock, Joel S. Gordon and Eduardo Perez. CarlosOrnella Eduardo Dubaz. Peredo, Philadelphia, Susan HPA. Smith, Javier Cote-Sierra and Jon Lenn. 020 CalcitoninPrinceton, gene-related NJ. peptide (CGRP) induces endothelial cells (EC) to 515 ResearchTopical applicationTriangle Park, of NC. acidic formulation alleviates psoriatic symptoms 530**bias IL-17C, Langerhans TNFα and cell IL-36 (LC) antigencompensate presentation for loss of IL-6towards and aidentify Th17 response novel in imiquimod-induced psoriasis model. Sung Woo Kim, Su Hwan Kim, Sin throughsignals induction facilitating of thesoluble transition mediators. between Wanhong uninvolved Ding, Lori and L Stohl,involved 006 Immunomodulatory effects of AM1030, a topical 5-HT2B receptor antagonistHee Lee and in development Se Kyoo Jeong. for Daejeon, atopic dermatitis. Korea (the NiklasRepublic Palmqvist of). , Max Johnpsoriasis A Wagner, skin. Linghui Philip Klenotic Xu and ,Richard Andrew David Johnston, Granstein. Thomas New McCormick York, NY. and 516 Siller,Brimonidine Anders Sjödin, tartrate Helena inhibits Arozenius, norepinephrine Christina plus Wenglén, adenosine-5’- Anna-Carin 021* ElevatedNicole Lthymic Ward. stromalCleveland, lymphopoietin OH and Ann Arbor, expression MI. in the skin blocks Ryde,triphosphate-induced Lars Pettersson, Cecilia interleukin Klint, 6Anna and Pramhed,interleukin Anna 8 production Löfdahl and by 531 breastNitric carcinogenesis. oxide releasing Shadmehr nanoparticles Demehri effectively, Trevor J Cunningham, prevent Sindhu Gunillahuman Ekström. dermal Lund,microvascular Sweden. endothelial cells. Claire Guo, Lori L Stohl Manivasagam,Propionibacterium Melissa acnes Meyer, induced David Denardo,inflammation Raphael by Kopan both clearing and Wayne the 007 Phenotypicand Richard analysis David Granstein. of dendritic New cells York, infiltrating NY. a spontaneous model Yokoyama.organism St. and Louis, inhibiting MO and microbialCincinnati, stimulation OH. of the innate immune 517 ofQuantitative basal cell carcinoma. correlation Christopher of pruritus Nirschl with, Yong functional Liu, Pinru connectivityWu, Karyn MRI in 022 Topicalresponse. application Min Qin ,of Angelo eupatilin Landriscina, ameliorates Jamie atopic Rosen, dermatitis-like George W Agak, skin Haitzthe brainand Niroshana of mice with Anandasabapathy. psoriasiform dermatitis. Boston, MA. Xiping Liu, Yasutomo Imai lesionsStephanie of NC/Nga Kao, Gabrielle mice. Young Wei, Min Karin Park Blecher,, Ji Hyun Josephine Lee, Ye JinBonventre, Lee and JunAlicea 008 Potentialand Sam Hwang.mechanisms Milwaukee, for loss WI. of hair follicle immune privilege in youngClendaniel, Lee. Seoul, Josephine Korea Stacey(the Republic Harper, of). Brandon Adler, Joel Friedman, + 518 patientsThe antimicrobial with alopecia peptide areata followinghuman beta-defensin hepatitis 3B inducesvaccination. regulatory T 023 CD8Joshuaαα T Nosanchuk, cells contribute Jenny to Kim lichen and planus Adam Friedman.independence Los Angeles,of LAMP1- CA; Christophercell. Thomas Richardson Schwarz,, AnikaElaine Bruhs Gilmore and and Agatha Brian Schwarz. Poligone. Kiel, Rochester, Germany. NY. meditatedBronx, NY degranulation. and Corvallis, OR.Bing Li, Xiuwen Sun and Gang Wang. Xi’an, 009*519 CCL17The antimicrobial attenuates tumor peptide immunity cathelicidin by increasing LL-37 induces regulatory semaphorin T cells and 3A 532 China.Intradermal administration of norepinephrine (NE) and adenosine-5’- Th2production cells while in decreasing normal human myeloid-derived epidermal keratinocytes.suppressor cells Yoshie in tumor Umehara , 024 Immunomodulatorytriphosphate (ATP) effectsinduces ofinterleukin-6 nanoparticles (IL-6) on andthe CXCL1contact expression microenvironment.Yayoi Kamata, Mitsutoshi Makoto Tominaga, Sugaya, Sohshi Francois Morimura, Niyonsaba, Tomonori Hideoki Oka, Ogawa hypersensitivityin murine skin. responseLori L Stohl in, WanhongC57BL/6 hairless Ding, Richard mice. Samreen David Granstein Jatana, and Hirakuand Kenji Suga, Takamori. Tomomitsu Urayasu-shi, Miyagaki, JapanYuichiro and Tsunemi, Bunkyo-ku, Yoshihide Japan. Asano, BrianJohn C APalmer Wagner. and New Lisa York, A DeLouise. NY. Rochester, NY. 520 YayoiAntimicrobial Tada, Takafumi and Kadonoanti-inflammatory and Shinichi Sato. effects Tokyo, ofHelicobacter Japan. pylori- 025533 CapturingThe chronic functional wound microbiomeconservation as betweena biomarker human for clinicalskin and outcomes. mouse DC 010 Distinctivederived synthetic downmodulation antimicrobial of plasmacytoidpeptides against dendritic Staphylococcus cell by vitaminaureus systemsMichael for Loesche generating, Sue E.better Gardner, vaccines. Brendan Eynav P KlechevskyHodkinson,. SaintAmanda Louis, Tyldsley, D3in analogue the skin. Peterin its interferon-I Song, Sunhyoα production Ryu, Hyomi and Hahn, chemotactic Yoonkyung activity. Park and MO.Joseph Horwinski, Sanaa Boudhar, David J Margolis and Elizabeth A Grice. TakahiroCheryl A. Suzuki Armstrong., Yoshiki Aurora, Tokura. CO; Hamamatsu, Denver, CO Japan. and Gwangju, Korea (the 026* HumanPhiladelphia, skin is protected PA and Iowa by fourCity, functionallyIA. and phenotypically 011** ARepublic wave of of).regulatory T cells into neonatal skin mediates tolerance to 534 discreteTargeting populations tumor-associated of resident macrophages and recirculating with anti-CSF-1R memory T cells.antibodies Rei 521* commensalNociceptive microbes sensory . Tiffanyfibers driveC Scharschmidt IL-23 from, KimberlyCD301b+ S dermalVasquez, DC Hong- and Watanabeas a strategy, Ahmed for inhibitingGehad, Chao T cellYang, lymphoma Laura Campbell, tumorigenesis. Jessica EmberleySam Hwang , Anprovide Truong, protection Sofia V. Gearty, from cutaneousMariela L Pauli,C. albicans Audrey infection. Nosbaum, Sakeen Michael Wali Teague,Xuesong Victor Wu Huang,and Yasutomo Tiago R Imai.Matos, Milwaukee, Thomas S. WI. Kupper and Rachael Otto,Kashem James, Daniel J Moon, Kaplan. Abul Minneapolis, K. Abbas, Michael MN. A Fischbach and Michael 535 Clark.Commensal Boston, MA.microbiota-responsive basophils promote atopic dermatitis- 522* DavidDermal Rosenblum. adipocytes San protect Francisco, against CA; Bethesda,invasive Staphylococcus MD and Charlestown, aureus skin 027 Novelassociated STAT3 inhibitoritch. Landon LLL12 K. significantlyOetjen, Changxiong reduces Guo, IL-17, Madison IL-22, andR. Mack, IFN- MA.infection. Lingjuan Zhang, Christian F. Guerrero-Juarez, Tissa Hata, Raul gammaTimothy mRNA M. Whelan, expression Qin inLiu psoriatic and Brian PBMCs. S. Kim. Justin St. Louis, G Hastings MO. , Xiaoli 012 KeratinRamos, 17Maksim enhances Plikus the and chemotaxis Richard L Gallo.of neutrophils San Diego, through CA and regulating Irvine, CA. 536 Zhang,Three-dimensional Jiayuh Lin, Chenglong printing Li andof chemotherapeutic Henry K Wong. Columbus, and antibiotic OH. eluting 523 chemokineIL-9/IL-9R CXCL1of epidermal secretion keratinocytes in keratinocytes in atopic via dermatitis:PI3k/AKT/NF-κ IL-9B induces 028* GILT-mediatedfibers, seeds, processing and discs offor a localized self and melanomadrug delivery antigen in cutaneous in thymic disease. pathway.IL-8 production Er-Le Dang through, Liang STIM1Jin, Chang-xu activation Han, Bing and Li,ERK Man phosphorylation. Jiang and epithelialJeffery cellsA Weisman promotes, Nadine deletion Marwan and Kaskas, regulatory Adam T Hcells. Green, Karen David Taraszka H GangChih-Hung Wang. LeeXi’an,, Chien-Hui China. Hong and Yu Hsin-Su. Kaohsiung, Taiwan; HastingsBallard,, MatthewJeffery J Ambrose,Rausch, Todd Lin SunC. Metzger,and David Michael K Mills. Waterfield,Shreveport, Jessica LA and 013* ContributionsTaipei, Taiwan ofand skin Zhunan, resident Taiwan. and recirculating memory T cells to CortezRuston, and LA. Mark S. Anderson. Phoenix, AZ and San Francisco, CA. depigmentation in vitiligo. Jillian Richmond, Mehdi Rashighi, Priti Agarwal and John E Harris. Worcester, MA.

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1 19 92 PPosteroster P Presentationsresentations // aabstractbstract ttitlesitles

Adaptive Immunity & Vaccination 537014 C.Acne elegans vaccines as a targetingmodel to screensecretory natural CAMP human factor odors of Propionibacterium produced by the 553* The human skin virome and its interactions with the host microbiome. All orals [designated with an asterisk (*)] listed below are presented in the humanacnes. Chun-Mingskin microbiome. Huang .Sung-Min San Diego, Wang CA. , Chun-Ming Huang. Taoyuan, Geoffrey D Hannigan, Jacquelyn Meisel, Amanda Tyldsley, Qi Zheng, Adaptive Immunity & Vaccination Minisymposium on Saturday, May 9, 2015, 015* TaiwanIdentifying and San Merkel Diego, polyomavirus-specific CA. CD4+ and CD8+ T-cells in Brendan P Hodkinson, Adam J SanMiguel, Samuel Minot, Frederic D from 12:30-3:30 pm in Salon D, Hilton Atlanta. Orals designated by two asterisks 538 ReducingMerkel cell flightless carcinoma I expression patients’ tumor-infiltratingdecreases severity of lymphocytes.psoriasis in Dafina an Bushman and Elizabeth A Grice. Philadelphia, PA. (**) will be presented during a Plenary Session. Orals designated by three imiquimod-inducedIbrani, Jayasri G Iyer, murine Natalie modelVandeven, . Zlatko Natalie Kopecki Miller,, Heng Olga Chong, Afanasiev, Gink 554 Skin microbiome characterizations are biased by sequencing approach. asterisks (***) will be presented during the Interdisciplinary Spotlight: Skin Yang,David Shireen Koelle and Sidhu, Paul Jan Nghiem. Ibbetson Seattle, and Allison WA. Cowin. Adelaide, Australia. Jacquelyn Meisel, Geoffrey D Hannigan, Amanda Tyldsley, Adam J Cancer Minisymposium on Friday, May 8, 2015, from 2:00 – 5:00 pm in the Grand 539016* ProbioticRegulatory activity T cells facilitate of S. epidermidis cutaneous in the wound skin microbiomehealing. Audrey inhibits Nosbaum the , SanMiguel, Brendan P Hodkinson, Qi Zheng and Elizabeth A Grice. Ballroom, Hilton Atlanta. growthMonika of Ettinger, T. rubrum: Hong-An A fungal Truong, nail treatment. Mariela L HongPauli, TsouSofia, V.Pei-Yi Gearty, Yu, Abul K. Philadelphia, PA. ShintaAbbas Maritoand Michael and Chun-Ming David Rosenblum. Huang. Taoyuan, San Francisco, Taiwan CA. and San Diego, CA. 555 Recirculating dermal IL-17-producing Vγ4+ γδT cells display memory-like + + 001 RON2315: A novel human biologic for the topical treatment of psoriasis. 540017 TypeQuantification 2 human papillomavirus of CD69 CD103 E7 skin can T attenuateRM cells in chronic NF-κB in atopic human dermatitis. responses. Francisco Ramirez-Valle, Jason Cyster. San Francisco, CA. Thomas Gadek. Portola Valley, CA. epidermalSeoHyeong keratinocytes. KIM, Chang Ook Young Park, Min Jung Park U Shin,, Yunhee Ji Yeon Ryu, Noh, Ju Hee Shan Han, Jin, 556 TLSP induced phosphorylation of L-plastin in eosinophils and its 002* Blockade for CD155-TIGIT interaction is an effective therapy for JiHemin Hyun Lee,Lee andJungsoo Soon Lee, Yong Thomas Choi. Seoul, S. Kupper Korea and (the Kwang Republic Hoon of) Lee. and Seoul, implication in atopic dermatitis. Jung U Shin, Ji Yeon Noh, SeoHyeong melanoma. Takashi Inozume, Tomonori Yaguchi, Yutaka Kawakami and Daejeon,Korea (the Korea Republic (the of)Republic and Boston, of). MA. KIM, Shan Jin, Hemin Lee, Jungsoo Lee, Howard Chu, Chang Ook Park and Shinji Shimada. Chuo, Japan and Shinjyuku, Japan. 541018* SignalingShared VH1-46 through antibody tachykinin gene receptors usage in regulates pemphigus the vulgaris pro-inflammatory predicts Kwang Hoon Lee. Seoul, Korea (the Republic of) and Boston, MA. 003 Migratory DC temper subcutaneous immunity through key tolerance andantibody type 2-biasing cross-reactivity functions to ofdesmoglein mast cells. 3 Tina and L.rotavirus Sumpter , VP6.Olga Michael 557* Spatial expression of RGD-binding integrins on keratinocytes control pathways. Niroshana Anandasabapathy, Christopher Nirschl, Yong Liu, Tkacheva,Jeffrey Tejada William Cho ,Schufesky, Christoph AdrianEllebrecht, Morelli Christoph and Adriana Matthias T Larregina. Hammers, homeostatic and UV-induced Langerhans cell migration by activating Shamim Mollah, Rachel E. Feder, Pinru Wu, Peter Sage and Arlene H Pittsburgh,Gopal Sapparapu, PA. James Crowe and Aimee S Payne. Philadelphia, PA and latent TGFβ Javed Mohammed, Aleh Bobr, Brian Astry, Alina G Bridges Sharpe. Boston, MA and New York, NY. 542 MicrobiomeNashville, TN. study with an in vitro reconstructed skin. Sabrina Leoty- and Daniel Kaplan. Minneapolis, MN and Rochester, MN. 004 Rationale and design of a novel dendritic cell targeted vaccine for basal 019* OkombiNext generation, Loreleï Valla-Dury, T cell receptor Celine sequencing Lebeux, Valérie reveals Cenizo, complex Valerie T cell Andre- 558 A requirement for pDC in the initiation of psoriasiform inflammation. cell carcinoma. Karyn Haitz, Steven R Barthel, Yong Liu, Christopher Frei,dynamics Anne inVianney Alopecia and Areata Sebastien . Annemieke Cadau. Lyon,de Jong France., Luzhou Xing, Ali Alexis Griffith, Matthew Hadiono, Rachel Davis and Daniel Popkin. Nirschl, Ervin Epstein and Niroshana Anandasabapathy. Boston, MA and 543* Cell-specificJabbari, Zhenpeng inflammatory Dai, Vera Hresponse Price, Madeleine to short-chain Duvic, fatty David acids Norris, produced Cleveland, OH. Oakland, CA. byMaria P. acnes. Hordinsky, James Julian Asbury Mackay-Wiggan, Sanford, Richard Raphael L Gallo. Clynes San Diego, and Angela CA. 559 Fisetin, a small molecule and a natural inhibitor of mTOR for treating 005 An ex vivo skin model that combines topical skin penetration and Th17 544* PD-1Christiano. regulates New imiquimod-induced York, NY; San Francisco, psoriasiform CA; Houston, dermatitis TX; Denver, through CO and psoriasis. Jean Christopher Chamcheu, Maria Ines Chaves-Rodriquez, stimulation. Mary Bedard, Steven Cook, Leandro Santos, Jessica Neil, inhibitionMinneapolis, of innateMN. IL-17A expression by γδ low T Cells. Xuesong Wu, Imtiaz Siddiqui, Vaqar Adhami, Deeba N Syed, Shah-Johan Dodwad and Carlos Eduardo Peredo, Susan H Smith, Javier Cote-Sierra and Jon Lenn. 020 YasutomoCalcitonin Imai, gene-related Natarajan peptide Ayithan, (CGRP) Li Wang induces and Sam endothelial Hwang. Milwaukee, cells (EC) to Hasan Mukhtar. Madison, WI. Research Triangle Park, NC. WI.bias Langerhans cell (LC) antigen presentation towards a Th17 response 560* LTA from commensal bacteria modulates keratinocyte SCF production to 545 Secretsthrough from induction the past: of solubleNatural productsmediators. and Wanhong the future Ding ,of Lori topical L Stohl, maintain mast cells in the skin . Zhenping Wang, Xiaojun Sun and Anna 006 Immunomodulatory effects of AM1030, a topical 5-HT2B receptor antagonist in development for atopic dermatitis. Niklas Palmqvist, Max anti-infectives.John A Wagner, Cassandra Linghui Xu L and Quave Richard, James David Lyles, Granstein. Kate Nelson, New JefferyYork, NY. S. Di Nardo. La Jolla, CA. Siller, Anders Sjödin, Helena Arozenius, Christina Wenglén, Anna-Carin 021* Kavanaugh,Elevated thymic Corey stromal Parlet, Heidilymphopoietin Crosby and expression Alex Horswill. in the Atlanta, skin blocksGA and 561 Opposing roles for Neurokinin-1 receptor in skin resident and circulating Ryde, Lars Pettersson, Cecilia Klint, Anna Pramhed, Anna Löfdahl and Iowabreast City, carcinogenesis. IA. Shadmehr Demehri, Trevor J Cunningham, Sindhu immune cells. Yi Fritz, Doina Diaconu, Maya Camhi, Thomas McCormick Gunilla Ekström. Lund, Sweden. 546 PsoriasinManivasagam, (S100A7) Melissa regulates Meyer, markers David Denardo, of epidermal Raphael differentiation. Kopan and Wayne and Nicole L Ward. Cleveland, OH. 007 Phenotypic analysis of dendritic cells infiltrating a spontaneous model Anna-KarinYokoyama. St.Ekman Louis,, Jenny MO and Vegfors, Cincinnati, Cecilia BivikOH. and Charlotta Enerbäck. 562 Robust induction of innate epidermal response genes by petrolatum of basal cell carcinoma. Christopher Nirschl, Yong Liu, Pinru Wu, Karyn 022 Linköping,Topical application Sweden. of eupatilin ameliorates atopic dermatitis-like skin sheds light on its function in preventing cutaneous infections. Dana Haitz and Niroshana Anandasabapathy. Boston, MA. 547 Inhibitionlesions of NC/Ngaof adhesion mice. proteins Young Min expression Park, Ji Hyunin human Lee, Yedermal Jin Lee and Jun Malajian, Joel M Corrêa da Rosa, Avner Shemer, James G Krueger and 008 Potential mechanisms for loss of hair follicle immune privilege in microvascularyoung Lee. Seoul, endothelial Korea (the cells Republic exposed of). to TNF-α by a Sambucus nigra Emma Guttman-Yassky. New York, NY and Tel-Aviv, Israel. + patients with alopecia areata following hepatitis B vaccination. 023 extractCD8αα Mathilde T cells contribute Frechet, Lionel to lichen Valenti, planus Pierre-Gilles independence Markioli, of LAMP1- Patrick 563 Clusters of dermal Bartonella henselae may be a functional biofilm. Christopher Richardson, Elaine Gilmore and Brian Poligone. Rochester, NY. Lafitte,meditated Frederic degranulation. Maccario Bing and LiJean-François, Xiuwen Sun Nicolay.and Gang Monaco, Wang. Xi’an, Monaco. Marna Ericson, Melissa Weber-Sanders, Gislaine Viera-Damiani, Marlene 009* CCL17 attenuates tumor immunity by increasing regulatory T cells and 548 CoincidentChina. therapeutic light plus ultrasound for P. acnes and S. aureus Neves da Silva, Vitor Pelegati, Carlos Lenz Cesar and Paulo Velho. Th2 cells while decreasing myeloid-derived suppressor cells in tumor 024 biofilmImmunomodulatory eradication. Tessie effects B McNeelyof nanoparticles, Mark Schafer on the and contact Adam Dakin. Minneapolis, MN and Campinas, Brazil. microenvironment. Makoto Sugaya, Sohshi Morimura, Tomonori Oka, Ambler,hypersensitivity PA. response in C57BL/6 hairless mice. Samreen Jatana, 564 A blockade of lysophosphatidic acid - lysophosphatidic acid receptor 1 Hiraku Suga, Tomomitsu Miyagaki, Yuichiro Tsunemi, Yoshihide Asano, 549 ImprovedBrian C Palmer understanding and Lisa A ofDeLouise. the mechanistic Rochester, aspects NY. of skin allergy – cascade augments murine allergic skin inflammation. Ken Igawa, Yoshiko Yayoi Tada, Takafumi Kadono and Shinichi Sato. Tokyo, Japan. 025 studiesCapturing of the functional fluorescent conservation contact sensitizer between TRITC.human Isabella skin Karlssonand mouse, DC Itoh and Hiroo Yokozeki. Tokyo, Japan. 010 Distinctive downmodulation of plasmacytoid dendritic cell by vitamin Kristinsystems Samuelsson, for generating Carl betterSimonsson, vaccines. Leopold Eynav Ilag, Klechevsky Charlotte. Saint Jonsson, Louis, Ann- 565 Dendritic cells display nanomolar sensitivity to zinc pyrithione-induced D3 analogue in its interferon-α production and chemotactic activity. ThereseMO. Karlberg and Ulrika Nilsson. Stockholm, Sweden and Gothenburg, zinc ion dysregulation causing heat shock and metal stress response Takahiro Suzuki, Yoshiki Tokura. Hamamatsu, Japan. 026* Sweden.Human skin is protected by four functionally and phenotypically gene expression. Sophia L Park, Georg T Wondrak. Tucson, AZ. 011** A wave of regulatory T cells into neonatal skin mediates tolerance to 550 Therapeuticdiscrete populations intradermal of resident delivery andof tumorrecirculating necrosis factor-alphamemory T cells. Rei 566 Effect of IL-17 on an organotypic model of psoriasis Michael Allen commensal microbes . Tiffany C Scharschmidt, Kimberly S Vasquez, Hong- antibodiesWatanabe, Ahmedusing tip-loaded Gehad, Chao dissolvable Yang, Laura microneedle Campbell, Jessicaarrays. Geza Emberley Erdos , Bachelor, Seyoum Ayehunie, Tim Landry, Zachary Stevens, Cristy Hedin, An Truong, Sofia V. Gearty, Mariela L Pauli, Audrey Nosbaum, Michael EmrullahTeague, Victor Korkmaz, Huang, Emily Tiago Friedrich, R Matos, Mohamed Thomas Ramadan,S. Kupper andAlicia Rachael R Mathers, Alexander Armento and Mitchell Klausner. Ashland, MA. Otto, James J Moon, Abul K. Abbas, Michael A Fischbach and Michael BurakClark. Ozdoganlar,Boston, MA. Newell Washburn and Louis D. Falo. Pittsburgh, PA. 567 C-type lectin receptors upregulated in skin of Ptpn6/Shp-1-deficient David Rosenblum. San Francisco, CA; Bethesda, MD and Charlestown, 551027 Interferon-gammaNovel STAT3 inhibitor enhances LLL12 significantly TLR3 expression reduces and IL-17,anti-viral IL-22, activity and IFN- mice with neutrophilic dermatosis-like disease. Andrew Nesterovitch, MA. ingamma keratinocytes. mRNA expression Shin Morizane in psoriatic, Ai Kajita, PBMCs. Tetsuya Justin Takiguchi, G Hastings Takenobu, Xiaoli Zarema Arbieva, Daniel Toth, Adrienn Markovics, Tibor Rauch, Michael 012 Keratin 17 enhances the chemotaxis of neutrophils through regulating Yamamoto,Zhang, Jiayuh Masao Lin, Chenglong Yamada and Li andKeiji Henry Iwatsuki. K Wong. Okayama, Columbus, Japan; OH. Tharp and Tibor Glant. Chicago, IL. chemokine CXCL1 secretion in keratinocytes via PI3k/AKT/NF-κB 028* Hamamatsu,GILT-mediated Japan processing and Kurashiki, of a self Japan. and melanoma antigen in thymic 568 SIG1191: A novel cosmetic functional ingredient with anti-inflammatory pathway. Er-Le Dang, Liang Jin, Chang-xu Han, Bing Li, Man Jiang and 552* IL-1epithelial and IL-36 cells are promotes the dominant deletion cytokines and regulatory in generalized T cells. pustularKaren Taraszka properties and skin hydrating potential. Karl Rouzard, Jose R Fernandez, Hastings, Matthew Rausch, Todd C. Metzger, Michael Waterfield, Jessica Gang Wang. Xi’an, China. psoriasis. Andrew Johnston, Xianying Xing, Liza Wolterink, Drew H Barnes, Michael Voronkov, Kristen L. Huber, Corey Webb, Jeffry B. Stock, Maxwell Cortez and Mark S. Anderson. Phoenix, AZ and San Francisco, CA. 013* Contributions of skin resident and recirculating memory T cells to William R Swindell, Mrinal Kumar Sarkar, J M Kahlenberg, Paul W Harms Stock, Joel S. Gordon and Eduardo Perez. Princeton, NJ. depigmentation in vitiligo. Jillian Richmond, Mehdi Rashighi, Priti and Johann Eli Gudjonsson. Ann Arbor, MI. Agarwal and John E Harris. Worcester, MA.

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93 1 20 PPosteroster P Presentationsresentations / /a abstractbstract t titlesitles

Adaptive569 xMAP Immunity® technology and & tapeVaccination stripping: High-throughput profiling of 014582* AcneUltraviolet vaccines radiation, targeting secretoryboth UVA andCAMP UVB, factor influences of Propionibacterium the composition of All orals [designatedstratum corneum with an IL-1RAasterisk and (*)] IL-1 listedα Nicola below Parisi are presented, P. J. Matts, in theR. Lever, acnes.the skin Chun-Ming microbiome. Huang Erin. San M Diego, Burns CA., Abdullah Shaheen, Anum Muzaffar, Adaptive ImmunityJ. Hadgraft & andVaccination Majella E. MinisymposiumLane. London, Unitedon Saturday, Kingdom May and 9, Egham,2015, 015* IdentifyingCamli Al-Sadek, Merkel Thompson polyomavirus-specific Foy, Mohammad CD4+ Abdelgawwad, and CD8+ T-cells Sumeira in from 12:30-3:30United pm Kingdom. in Salon D, Hilton Atlanta. Orals designated by two asterisks MerkelHuda, cell Prescilia carcinoma N Isedeh, patients’ Ranjit tumor-infiltrating Kumar, Travis Ptacek, lymphocytes. Henry W. DafinaLim, (**)570 will beThe presented cytosolic during nucleic a Plenary acid-sensing Session. pathways Orals designated play critical by threeroles in host IbraniIltefat, Jayasri H Hamzavi, G Iyer, CaseyNatalie D Vandeven,Morrow, Craig Natalie A Elmets Miller, and Olga Nabiha Afanasiev, Yusuf. asterisks (***)restriction will be presentedof modified during vaccinia the Interdisciplinaryvirus Ankara replication. Spotlight: Liang Skin Deng , DavidBirmingham, Koelle and AL Paul and Nghiem. Detroit, Seattle,MI. WA. Cancer MinisymposiumWeiyi Wang, Cristian on Friday, Serna-Tamayo, May 8, 2015, Zhaoyangfrom 2:00 –Niu, 5:00 Peihong pm in theDai andGrand 016*583 RegulatoryClinicopathological T cells facilitate features cutaneous of Bowen’s wound disease healing. resistance Audrey to Nosbaum methyl , Ballroom, HiltonStewart Atlanta. Shuman. New York, NY. Monikaaminolevulinate Ettinger, photodynamicHong-An Truong, therapy. Mariela TamaraL Pauli, Gracia-CazañaSofia V. Gearty,, Jesus Abul K. 571 Lewisite-induced cutaneous injuries in murine skin. Mohammad Athar, AbbasVera-Alvarez, and Michael Angeles David Juarranz, Rosenblum. Ievgenia San Francisco, Pastushenko, CA. Nerea Salazar, + + 001 RON2315:Changzhao A novel Li, Ritesh human K. Srivastava, biologic for Zhiping the topical Weng treatment and Farrukh of Afaq.psoriasis. 017 QuantificationSalvador Gonzalez of andCD69 CD103 Yolanda skin Gilaberte. TRM cells Barbastro, in chronic Spain; atopic Huesca, dermatitis. ThomasBirmingham, Gadek. AL.Portola Valley, CA. SeoHyeongSpain; Madrid, KIM, Chang Spain; OokBrussels, Park, BelgiumJung U Shin, and NewJi Yeon York, Noh, NY. Shan Jin, 002*572 BlockadeIL-27 participates for CD155-TIGIT in cutaneous interaction host is immune an effective suppression therapy in leprosy.for 584* HeminCircadian Lee, Jungsoo rhythm Lee,and skinThomas inflammation. S. Kupper and Amanda Kwang K HoonSuggs Lee., Jacqueline Seoul, melanoma.Kindra Kelly-Scumpia Takashi Inozume, Rosane, Tomonori MB Teles Yaguchi, and Robert Yutaka Modlin. Kawakami Los Angeles, and KoreaSelph, (the Minh Republic Lam andof) andElma Boston, D Baron. MA. Cleveland, OH. ShinjiCA. Shimada. Chuo, Japan and Shinjyuku, Japan. 018*585 SharedUltraviolet VH1-46 Radiation antibody (UVR) gene inducedusage in cytogeneticpemphigus vulgaris damage predictsin melanocytes 003573 MigratoryNegative DC regulation temper subcutaneous of noncanonical immunity NF-kB throughsignaling. keyBahram tolerance Razani . Los antibodyof White, cross-reactivity Hispanic and Black to desmoglein skin. Amrita 3 Dasguptaand rotavirus, Meena VP6. Michael Katdare. pathways.Angelesc, Niroshana CA and San Anandasabapathy Francisco, CA. , Christopher Nirschl, Yong Liu, JeffreyHampton, Tejada VA Cho and, Christoph Norfolk, VA.Ellebrecht, Christoph Matthias Hammers, 574 ShamimMacrophages Mollah, infectedRachel E. with Feder, Mycobacterium Pinru Wu, Peter leprae Sage failand to Arlene activate H 586 GopalEvaluation Sapparapu, of DNAJames damage Crowe biomarkerand Aimee expression S Payne. Philadelphia, in UV-exposed PA andhuman Sharpe.appropriate Boston, antimicrobial MA and New York,pathways. NY. Philip Oliver Scumpia, Giovanni Nashville,keratinocytes TN. using sphingomyelin treatment. Kevin T Campbell, Kristina 004 RationaleBotten, Kindraand design Kelly-Scumpia, of a novel Robertdendritic Modlin cell targetedand Stephen vaccine Smale. for Losbasal 019* NextBishard, generation Karissa TCardenas cell receptor and Lilysequencing Laiho. San reveals Luis Obispo, complex CA. T cell cellAngeles, carcinoma. CA. Karyn Haitz, Steven R Barthel, Yong Liu, Christopher 587* dynamicsAlternative in Alopecia keratin Areata 17 expression . Annemieke variation de Jong is, Luzhouinduced Xing, by different Ali doses Nirschl, Ervin Epstein and Niroshana Anandasabapathy. Boston, MA and Jabbari,of narrow-band Zhenpeng Dai,ultraviolet Vera H BPrice, in keratinocytes Madeleine Duvic, via Erk1/2-dependent David Norris, Oakland, CA. Mariamechanism. Hordinsky, Er-Le Julian Dang Mackay-Wiggan,, Chang-xu Han, Raphael Liang Jin Clynes and Gang and Angela Wang. Xi’an, 005 An ex vivo skin model that combines topical skin penetration and Th17 Christiano.China. New York, NY; San Francisco, CA; Houston, TX; Denver, CO and Photobiologystimulation. Mary Bedard, Steven Cook, Leandro Santos, Jessica Neil, 588 Minneapolis,Involvement MN. of AhR-dependent COX-2 generation in the mechanism All oralsCarlos [designated Eduardo withPeredo, an asterisk Susan H (*)] Smith, listed Javier below Cote-Sierra are presented and Jon in theLenn. 020 Calcitoninof antifungal gene-related voriconazole-induced, peptide (CGRP) UV-associatedinduces endothelial skin cancer cells (EC) to PhotobiologyResearch Minisymposium Triangle Park, NC. on Saturday, May 9, 2015, from 12:30-3:30 pm in biasdevelopment. Langerhans cellShigeki (LC) Ikeya antigen, Jun-ichi presentation Sakabe and towards Yoshiki a Tokura. Th17 response 006Salon ImmunomodulatoryC, Hilton Atlanta. Orals effects designated of AM1030, by two aasterisks topical 5-HT(**) will receptor be presented throughHamamatsu, induction Japan. of soluble mediators. Wanhong Ding, Lori L Stohl, 2B KIP1 duringantagonist a Plenary Session.in development Orals designated for atopic by dermatitis. three asterisks Niklas (***) Palmqvist will be, Max 589* JohnThe A tumorWagner, suppressor Linghui Xu p27 and Richard in keratinocytes David Granstein. is regulated New York, via anNY. presentedSiller, during Anders the Sjödin, Interdisciplinary Helena Arozenius, Spotlight: Christina Skin Cancer Wenglén, Minisymposium Anna-Carin on 021* Elevatedautocrine thymic mechanism stromal involvinglymphopoietin the aryl expression hydrocarbon in the receptor skin blocks (AHR). Friday,Ryde, May Lars8, 2015, Pettersson, from 2:00 Cecilia – 5:00 Klint, pm inAnna the Pramhed,Grand Ballroom, Anna Löfdahl Hilton andAtlanta. breastThomas carcinogenesis. Haarmann-Stemmann Shadmehr, DemehriMarius Pollet, Trevor and J Cunningham,Jean Krutmann. Sindhu Gunilla Ekström. Lund, Sweden. Manivasagam,Düsseldorf, Germany. Melissa Meyer, David Denardo, Raphael Kopan and Wayne 007575 PhenotypicComparison analysis of the of effects dendritic of continuous cells infiltrating and pulsed-wave a spontaneous light model 590 Yokoyama.Combining St. ethanolLouis, MO and and UVB Cincinnati, results in augmentedOH. acute cutaneous and of photodynamicbasal cell carcinoma. therapy. Christopher Hideyuki Masuda Nirschl,, YongMakoto Liu, Kimura Pinru Wu, and Karyn Akimichi 022 Topicalsystemic application effects viaof eupatilinaugmented amelioratesPlatelet-activating atopic dermatitis-like factor production. skin HaitzMorita. and NiroshanaTokyo, Japan Anandasabapathy. and Nagoya, Japan. Boston, MA. lesionsRavi Sahuof NC/Nga, Jonathan mice. Weyerbacher, Young Min Park Raymond, Ji Hyun Lloyd Lee, Konger Ye Jin Lee and and Jeffrey Jun B. 008576 PotentialRole of UVB-inducedmechanisms forIL-1 loss and ofneutrophils hair follicle in immune dermal collagenprivilege alterationin youngTravers. Lee. Indianapolis, Seoul, Korea IN.(the Republic of). + patientsin murine with skin. alopecia Meena areata Sharma following, Victoria hepatitis Werth. Philadelphia, B vaccination. PA. 023591** CD8 Silymarinαα T cells mediated contribute DNA to repair lichen is planus a mechanism independence for suppression of LAMP1- of UVB 577 ChristopherLight emitting Richardson diode-generated, Elaine Gilmore red lightand Brian alters Poligone. human Rochester,fibroblast NY. meditatedinduced Tregdegranulation. cells and prevention Bing Li, Xiuwen of photocarcinogenesis. Sun and Gang Wang. Hui Xi’an, Xu, Hui Li, 009* CCL17proliferation attenuates rate tumor and immunitymigration byspeed increasing through regulatory modulation T cells of andthe PI3K/ China.Donggou He, Tripti Singh, Ram Prasad and Santosh K Katiyar. Birmingham, Th2AKT cells pathway. while decreasing Jared R Jagdeo myeloid-derived, Andrew Mamalis, suppressor Roslyn cells Rivkah in tumor Isseroff 024 ImmunomodulatoryAL. effects of nanoparticles on the contact microenvironment.and William Murphy. Makoto Sacramento, Sugaya, SohshiCA; Brooklyn, Morimura, NY and Tomonori Mather, Oka, CA. 592 hypersensitivityRab23 regulates response UVB-induced in C57BL/6 autophagy hairless via ERK/mTORmice. Samreen Signaling Jatana, 578* HirakuA meta-analysis Suga, Tomomitsu of microRNAs Miyagaki, expression Yuichiro Tsunemi, profile Yoshihidein UV-radiation Asano, BrianPathway C Palmer in epidermal and Lisa A keratinocytes. DeLouise. Rochester, Min Huang NY. , Jian Qiang and Yayoiinduced Tada, skinTakafumi tumors Kadono Ram Prasad and Shinichi, Tripti Sato. Singh, Tokyo, Mudit Japan. Vaid and Santosh K 025 CapturingChengxin functional Li. Xi’an, China conservation and Beijing, between China. human skin and mouse DC 010 DistinctiveKatiyar. Birmingham, downmodulation AL. of plasmacytoid dendritic cell by vitamin 593* systemsPlatelet-activating for generating factor better receptor vaccines. agonistsEynav Klechevsky generated. Saintby radiation Louis, 579***D3 Drinking analogue green in its tea interferon- inhibits αphotocarcinogenesis production and chemotactic in mice by upregulating activity. MO.therapy thwart host anti-tumor immunity . Ravi Sahu, Raymond Lloyd Takahirothe levels Suzuki of ,miRNA-29 Yoshiki Tokura. and subsequently Hamamatsu, inhibitionJapan. of DNA 026* HumanKonger skin and is Jeffreyprotected B. Travers.by four Indianapolis,functionally IN.and phenotypically 011** A wavehypermethylation of regulatory Tin cells tumors into Santosh neonatal K Katiyar skin mediates, Tripti Singh tolerance and Ramto 594* discreteLipid oxidation populations patterns of resident and kineticsand recirculating in keratinocytes memory Tundergoing cells. Rei commensalPrasad. Birmingham, microbes . TiffanyAL. C Scharschmidt, Kimberly S Vasquez, Hong- Watanabesenescence-promoting, Ahmed Gehad, Chaostress Yang,or replicative Laura Campbell, senescence. Jessica Florian Emberley Gruber , 580 AnTGF Truong,-beta Sofia signaling V. Gearty, links E-cadherin Mariela L Pauli,loss to Audrey suppression Nosbaum, of UVB-induced Michael Teague,Marie Victor Sophie Huang, Narzt, TiagoIonela R Mariana Matos, Thomas Nagelreiter, S. Kupper Susanne and Karner, Rachael Otto,DNA James repair. J LeiMoon, Qiang Abul, Palak K. Abbas, Shah, MaryMichael Helen A Fischbach Barcellos-Hoff and Michael and Yu-Ying Clark.Johannes Boston, Grillari, MA. Katarzyna Figlak, Manuel Filzwieser, Valery Bochkov and DavidHe. Rosenblum.Chicago, IL and San New Francisco, York, NY. CA; Bethesda, MD and Charlestown, 027 NovelErwin STAT3 Tschachler. inhibitor Vienna, LLL12 Austriasignificantly and Graz, reduces Austria. IL-17, IL-22, and IFN- 581 MA.Toll-Like Receptor-4 deficiency enhances repair of ultraviolet radiation 595* gammaUVA and mRNA UVB expression induce different in psoriatic sets ofPBMCs. long Justinnon-coding G Hastings RNAs., ThomasXiaoli M. 012 Keratininduced 17 DNAenhances damage the in chemotaxis skin and prevents of neutrophils skin cancer. through Michelle regulating Chang , Zhang,Ruenger Jiayuh, Kazuyuki Lin, Chenglong Yo. Providence, Li and Henry RI and K Yokohama,Wong. Columbus, Japan. OH. chemokineMohammad CXCL1 O Ata, secretion Iman A inTamimi, keratinocytes Israr Ahmad, via PI3k/AKT/NF-Santosh K Katiyar,κB Craig 028*596 GILT-mediatedEffect of TNF processingα blockade of on a UV-induced self and melanoma changes antigen in the skin. in thymic Jamie pathway.A Elmets Er-Le and DangNabiha, Liang Yusuf. Jin, Birmingham, Chang-xu Han, AL. Bing Li, Man Jiang and epithelialLangenhan cells, Meena promotes Sharma, deletion Elizabeth and regulatory S Robinson, T Emilycells. Karen Privette, Taraszka Rui Gang Wang. Xi’an, China. HastingsFeng, Joyce, Matthew Okawa Rausch, and Victoria Todd Werth.C. Metzger, Phil, PA.Michael Waterfield, Jessica 013* Contributions of skin resident and recirculating memory T cells to 597* CortezDistinctive and Mark molecularS. Anderson. and Phoenix,cellular responsesAZ and San to Francisco, UVB in keratinoctyes CA. and depigmentation in vitiligo. Jillian Richmond, Mehdi Rashighi, Priti melanocytes. Liang Liu, Masashi Nakatani and Arianna Kim. New York, NY. Agarwal and John E Harris. Worcester, MA.

Notes:Notes:

1 21 94 PPosteroster P Presentationsresentations // aabstractbstract ttitlesitles

Adaptive Immunity & Vaccination 598***014 miR-30Acne vaccines is downregulated targeting secretoryin human CAMPsquamous factor cell of carcinomaPropionibacterium and UVB Pigmentation & Melanoma All orals [designated with an asterisk (*)] listed below are presented in the exposedacnes. Chun-Ming keratinocytes. Huang Deeba. San Diego,N Syed CA., Rahul K Lall, Nosheen Akhtar, Jack All orals [designated with an asterisk (*)] listed below are presented in the Adaptive Immunity & Vaccination Minisymposium on Saturday, May 9, 2015, 015* LongleyIdentifying and HasanMerkel Mukhtar. polyomavirus-specific Madison, WI. CD4+ and CD8+ T-cells in Pigmentation & Melanoma Minisymposium on Friday, May 8, 2015, from 2:00- from 12:30-3:30 pm in Salon D, Hilton Atlanta. Orals designated by two asterisks 599* VisibleMerkel light-induced cell carcinoma hyperpigmentation patients’ tumor-infiltrating in human skinlymphocytes. in vivo occurs Dafina in 5:00 pm in Salon AB, Hilton Atlanta. Orals designated by two asterisks (**) will be (**) will be presented during a Plenary Session. Orals designated by three dark,Ibrani but, Jayasri not inG lightIyer, Natalieskin, and Vandeven, is associated Natalie with Miller, differential Olga Afanasiev, induction of presented during a Plenary Session. Orals designated by three asterisks (***) will asterisks (***) will be presented during the Interdisciplinary Spotlight: Skin CCL18David Koelleand tyrosinase and Paul genes.Nghiem. Barbara Seattle, Rainer WA. , Ji Qi, Jo Martin, Aleksandra be presented during the Interdisciplinary Spotlight: Skin Cancer Minisymposium Cancer Minisymposium on Friday, May 8, 2015, from 2:00 – 5:00 pm in the Grand 016* Ogurtsova,Regulatory C.T cellsConover facilitate Talbot, cutaneous Sherry Leung, wound Luis healing. A Garza, Audrey Anna NosbaumL. Chien , on Friday, May 8, 2015, from 2:00 – 5:00 pm in the Grand Ballroom, Hilton Ballroom, Hilton Atlanta. andMonika Sewon Ettinger, Kang. Baltimore, Hong-An Truong, MD. Mariela L Pauli, Sofia V. Gearty, Abul K. Atlanta. 600 MixtureAbbas and of ArecaMichael catechu David Rosenblum.nuts and Alpinia San Francisco, katsumadai CA. seeds inhibits 017 Quantification of CD69+CD103+ skin T cells in chronic atopic dermatitis. 001 RON2315: A novel human biologic for the topical treatment of psoriasis. skin photoaging by inhibition of UVB-inducedRM 11β-hydroxysteroid 612 Small molecule inhibitors of protein kinase CK2 reduce proliferation and SeoHyeong KIM, Chang Ook Park, Jung U Shin, Ji Yeon Noh, Shan Jin, Thomas Gadek. Portola Valley, CA. dehydrogenase type 1 up-regulation. Jin-Ju Nam, Ji-Eun Park, Seok Kyun viability of melanoma cells in vitro. Erin Marie Dodd, Janeen H Trembley Hemin Lee, Jungsoo Lee, Thomas S. Kupper and Kwang Hoon Lee. Seoul, 002* Blockade for CD155-TIGIT interaction is an effective therapy for Yun and Seong-Joon Moon. Seongnam-si, Korea (the Republic of). and Rehana Leila Ahmed. Mpls, MN. Korea (the Republic of) and Boston, MA. melanoma. Takashi Inozume, Tomonori Yaguchi, Yutaka Kawakami and 601 Changes of genes in a time-dependent photoaged mouse model. Seon- 613 The role of KIT in early melanoma development. Christian Posch, 018* Shared VH1-46 antibody gene usage in pemphigus vulgaris predicts Shinji Shimada. Chuo, Japan and Shinjyuku, Japan. PIL Jin, Eun Young Seo, Chang-Eop Kim, In-kyung Oh and Jin-Ho Chung. Martina Sanlorenzo, Homayoun Moslehi, Igor Vujic, Juan Oses-Prieto, antibody cross-reactivity to desmoglein 3 and rotavirus VP6. Michael 003 Migratory DC temper subcutaneous immunity through key tolerance Seoul, Korea (the Republic of). Rosaura Esteve-Puig, Gary Green, Luz Feeney, Al Burlingame, Klemens Jeffrey Tejada Cho, Christoph Ellebrecht, Christoph Matthias Hammers, pathways. Niroshana Anandasabapathy, Christopher Nirschl, Yong Liu, 602 Solar simulated Ultraviolet radiation induces global histone Rappersberger and Susana Ortiz-Urda. San Francisco, CA; Boston, MA; Gopal Sapparapu, James Crowe and Aimee S Payne. Philadelphia, PA and Shamim Mollah, Rachel E. Feder, Pinru Wu, Peter Sage and Arlene H hypoacetylation in human HaCaT keratinocytes. Hong Sun, Xiaoru Zhang, Vienna, Austria and Torino, Italy. Nashville, TN. Sharpe. Boston, MA and New York, NY. Thomas Kluz, Lisa Gesumaria, Mary S Matsui and Max Costa. Tuxedo, NY 614 Neurotrophin receptors and perineural invasion in desmoplastic 019* Next generation T cell receptor sequencing reveals complex T cell 004 Rationale and design of a novel dendritic cell targeted vaccine for basal and Melville, NY. melanoma. Noah Frydenlund, Dominick Leone, Brendon Mitchell, Shi dynamics in Alopecia Areata . Annemieke de Jong, Luzhou Xing, Ali cell carcinoma. Karyn Haitz, Steven R Barthel, Yong Liu, Christopher 603 Antioxidants prevent ozone induced oxidative damage in human Yang and Meera Mahalingam. Boston, MA. Jabbari, Zhenpeng Dai, Vera H Price, Madeleine Duvic, David Norris, Nirschl, Ervin Epstein and Niroshana Anandasabapathy. Boston, MA and keratinocytes. Christian Oresajo, Giuseppe Valacchi, Claudia Sticozzi, 615* CD4, IL-17, and COX-2 are associated with inflammation in melasma. Maria Hordinsky, Julian Mackay-Wiggan, Raphael Clynes and Angela Oakland, CA. Nannan Chen and Yevgeniy Krol. Ferrara, Italy; Clark, NJ and New York, NY. Adriana Rodríguez-Arámbula, Juan P Castanedo-Cázares, Diego Cortés- Christiano. New York, NY; San Francisco, CA; Houston, TX; Denver, CO and 005 An ex vivo skin model that combines topical skin penetration and Th17 604 CXCL5 is secreted by UV irradiated skin cells and enhances CGRP release García, Bertha Torres-Álvarez and Karla Imelda Martínez-Rosales. San Luis Minneapolis, MN. stimulation. Mary Bedard, Steven Cook, Leandro Santos, Jessica Neil, in sensory neurons. Gitta Neufang, Olga Reichert, Dennis Roggenkamp, Potosi, Mexico and San Luis Potosí, Mexico. 020 Calcitonin gene-related peptide (CGRP) induces endothelial cells (EC) to Carlos Eduardo Peredo, Susan H Smith, Javier Cote-Sierra and Jon Lenn. Ludger Kolbe, Lara Terstegen, Franz Staeb and Horst Wenck. Hamburg, 616 An epithelial-mesenchymal transition in melanoma is associated with bias Langerhans cell (LC) antigen presentation towards a Th17 response Research Triangle Park, NC. Germany. acquired resistance to BRAF inhibition. Yiyin Erin Chen, Zhenyu Ji, 605 Autophagythrough induction and skin ofaging soluble . Raaj mediators. P Khusial Wanhong, Michelle Ding Slade,, Lori John L Stohl, Lyga and 006 Immunomodulatory effects of AM1030, a topical 5-HT2B receptor Michael Taylor, Jenny Chi-Ni Njauw, Goran Jonsson and Hensin Tsao. San John A Wagner, Linghui Xu and Richard David Granstein. New York, NY. antagonist in development for atopic dermatitis. Niklas Palmqvist, Max Uma Santhanam. Suffern, NY. Francisco, CA; Boston, MA and Lund, Sweden. 021* Elevated thymic stromal lymphopoietin expression in the skin blocks Siller, Anders Sjödin, Helena Arozenius, Christina Wenglén, Anna-Carin 606 Chemiexcitation of melanin derivatives induces cyclobutane dimers in 617* MT19c resensitizes metastatic melanoma cells to vemurafenib, breast carcinogenesis. Shadmehr Demehri, Trevor J Cunningham, Sindhu Ryde, Lars Pettersson, Cecilia Klint, Anna Pramhed, Anna Löfdahl and the dark. Douglas E. Brash, Sanjay Premi, Silvia Wallisch, Camila Mano, decreases tumor growth, and increases survival in a vemurafenib- Manivasagam, Melissa Meyer, David Denardo, Raphael Kopan and Wayne Gunilla Ekström. Lund, Sweden. Adam Weiner, Antonella Bacchiocchi, Kazumasa Wakamatsu, Etelvino resistant metastatic melanoma model. Alex Han, Michael Vezeridis, Yokoyama. St. Louis, MO and Cincinnati, OH. 007 Phenotypic analysis of dendritic cells infiltrating a spontaneous model Bechara, Ruth Halaban and Thierry Douki. New Haven, CT; Sao Paolo, Rakesh Singh, Leslie Robinson-Bostom, Martin A Weinstock and Richard 022 Topical application of eupatilin ameliorates atopic dermatitis-like skin of basal cell carcinoma. Christopher Nirschl, Yong Liu, Pinru Wu, Karyn Brazil; Toyoake, Japan and Grenoble, France. Moore. Providence, RI. lesions of NC/Nga mice. Young Min Park, Ji Hyun Lee, Ye Jin Lee and Jun Haitz and Niroshana Anandasabapathy. Boston, MA. 607 Signaling pathways that modulate the UVR response of human 618 Dual inhibition of CRD-BP and BRAF in BRAF-mutant Melanoma – A 008 Potential mechanisms for loss of hair follicle immune privilege in melanocytesyoung Lee. Seoul, . Zalfa Korea A Abdel-Malek (the Republic, Anne of). vonKoschembahr, Viki Swope + novel approach to overcome resistance to BRAF inhibitors. TaeWon patients with alopecia areata following hepatitis B vaccination. 023 andCD8 Rennyαα T cellsStarner. contribute Cincinnati, to lichen OH. planus independence of LAMP1- meditated degranulation. Bing Li, Xiuwen Sun and Gang Wang. Xi’an, Kim, Yaohui Gloria Xu, Vijayasaradhi Setaluri and Vladimir Spiegelman. Christopher Richardson, Elaine Gilmore and Brian Poligone. Rochester, NY. 608* UVB induces mast cell dermal recruitment and activation trough Madison, WI. 009* CCL17 attenuates tumor immunity by increasing regulatory T cells and S1PChina. production from human keratinocyte . Anna Di Nardo, Matthieu 024 Immunomodulatory effects of nanoparticles on the contact 619 Aspirin induces Nrf2-mediated transcriptional activation of heme Th2 cells while decreasing myeloid-derived suppressor cells in tumor Vanderberghe and Zhenping Wang. La Jolla, CA. oxygenase-1 in protection of human melanocytes from H O -induced microenvironment. Makoto Sugaya, Sohshi Morimura, Tomonori Oka, 609* Identificationhypersensitivity of response glycolysis-derived in C57BL/6 α-dicarbonyl hairless mice.metabolites Samreen asJatana the , 2 2 Brian C Palmer and Lisa A DeLouise. Rochester, NY. oxidative stress. Zhe Jian, Lingzhen Tang, Tianwen Gao and Chunying Li. Hiraku Suga, Tomomitsu Miyagaki, Yuichiro Tsunemi, Yoshihide Asano, smallest known endogenous UVA-photosensitizers in human skin cells Xi’an, China. Yayoi Tada, Takafumi Kadono and Shinichi Sato. Tokyo, Japan. 025 andCapturing reconstructed functional epidermis. conservation Georg Tbetween Wondrak human, Rebecca skin Justiniano, and mouse DC systems for generating better vaccines. Eynav Klechevsky. Saint Louis, 620 Depletion of melanoma fn14 by oligonucleotide-mediated exon 010 Distinctive downmodulation of plasmacytoid dendritic cell by vitamin Shuxi Qiao and Joshua D Williams. Tucson, AZ. skipping. Kristen M Beck, Sitharam Ramaswami, Wangyong Zeng and D3 analogue in its interferon-α production and chemotactic activity. 610 Low-levelMO. laser treatment of chemotherapy-induced alopecia: A 026* Human skin is protected by four functionally and phenotypically Matthew S Hayden. New York, NY. Takahiro Suzuki, Yoshiki Tokura. Hamamatsu, Japan. preclinical study in rats. Assuan Lens, Keyvan Nouri, Joaquin Jimenez and 621 High expression of Mcl-1 mediated by MEK–ERK1/2–STAT3 signaling 011** A wave of regulatory T cells into neonatal skin mediates tolerance to Tongyudiscrete Cao populations Wikramanayake. of resident Miami, and FL. recirculating memory T cells. Rei Watanabe, Ahmed Gehad, Chao Yang, Laura Campbell, Jessica Emberley pathway protects melanocytes and melanoma cells against ultraviolet commensal microbes . Tiffany C Scharschmidt, Kimberly S Vasquez, Hong- 611 Enhanced DNA repair in keratinocytes reconstituted into epidermal B-induced apoptosis. Takeshi Fukumoto, Tetsushi Iwasaki, Taro Okada, An Truong, Sofia V. Gearty, Mariela L Pauli, Audrey Nosbaum, Michael Teague, Victor Huang, Tiago R Matos, Thomas S. Kupper and Rachael equivalents. Dennis H. Oh, Katherine Ona-Vu. San Francisco, CA. Takanori Hashimoto, Youbin Moon, Masanobu Sakaguchi, Yasuo Fukami, Otto, James J Moon, Abul K. Abbas, Michael A Fischbach and Michael Clark. Boston, MA. Chikako Nishigori and Masahiro Oka. Kobe, Japan. David Rosenblum. San Francisco, CA; Bethesda, MD and Charlestown, 027 Novel STAT3 inhibitor LLL12 significantly reduces IL-17, IL-22, and IFN- 622* Y chromosome encoded TSPY proto-oncogene drives increased MA. gamma mRNA expression in psoriatic PBMCs. Justin G Hastings, Xiaoli melanoma cell aggressiveness . Maria L. Wei, Zhi-ming Huang, Yunmin 012 Keratin 17 enhances the chemotaxis of neutrophils through regulating Zhang, Jiayuh Lin, Chenglong Li and Henry K Wong. Columbus, OH. Li, Tatsuo Kido, Iwei Yeh, Kavari Korgavkar, Adi Nosrati, John Livingstone, chemokine CXCL1 secretion in keratinocytes via PI3k/AKT/NF-κB 028* GILT-mediated processing of a self and melanoma antigen in thymic Jillian W. Wong, Glynis Scott and Chris Lau. San Francisco, CA and pathway. Er-Le Dang, Liang Jin, Chang-xu Han, Bing Li, Man Jiang and epithelial cells promotes deletion and regulatory T cells. Karen Taraszka Rochester, NY. Gang Wang. Xi’an, China. Hastings, Matthew Rausch, Todd C. Metzger, Michael Waterfield, Jessica 623 Broadband light absorption characteristics of melanin: human skin 013* Contributions of skin resident and recirculating memory T cells to Cortez and Mark S. Anderson. Phoenix, AZ and San Francisco, CA. measurement beyond Chromameter and Mexameter. InSeok Seo, Hao depigmentation in vitiligo. Jillian Richmond, Mehdi Rashighi, Priti Ouyang. Skillman, NJ. Agarwal and John E Harris. Worcester, MA.

Notes: Notes:

1 95 22 PPosteroster P Presentationsresentations / /a abstractbstract t titlesitles

Adaptive624* CDK1 enhancesImmunity tumor initiation& Vaccination and stemness by interacting with 014640 AcneNotch1 vaccines confers targeting melanoma secretory resistance CAMP to factor temozolomide of Propionibacterium through NLRP1 All orals [designatedstem cell genes with inan human asterisk cancers. (*)] listed Yuchun below Luo are, Johnpresented J Arcaroli, in the Nicholas acnes.upregulation. Chun-Ming Zili Huang Zhai, Weimin. San Diego, Liu, CA.Manjinder Kaur, Yuchun Luo, David AdaptiveNguyen, Immunity Sucai & Vaccination Liu, Lekha Kutty, Minisymposium Stacey Bagby, on StevenSaturday, Robinson, May 9, 2015,William 015* IdentifyingNorris, Richard Merkel A. Spritz,polyomavirus-specific Charles A Dinarello CD4+ and andMayumi CD8+ Fujita.T-cells Aurora,in from 12:30-3:30Robinson, pm David in Salon Norris, D, Hilton Wells Atlanta. Messersmith Orals designatedand Mayumi by Fujita. two asterisks Aurora, MerkelCO and cell Denver, carcinoma CO. patients’ tumor-infiltrating lymphocytes. Dafina (**) will beCO presented and Denver, during CO. a Plenary Session. Orals designated by three 641**Ibrani Narrow, Jayasri band G UVBIyer, Natalietreatment Vandeven, of human Natalie vitiligo Miller, is associated Olga Afanasiev, with asterisks625 (***)Akt activation will be presented promotes during the the development Interdisciplinary of brain Spotlight: metastases Skin in a Davidinduction Koelle andof stem Paul cellNghiem. genes Seattle, for melanocyte WA. repopulation in the hair Cancer Minisymposiummouse model ofon melanoma. Friday, May Joseph 8, 2015, Cho from, James 2:00 Robinson,– 5:00 pm Rowan in the GrandArave, 016* Regulatoryfollicle and T cellsepidermis. facilitate Stanca cutaneous A Birlea wound, Nathaniel healing. B. Goldstein, Audrey Nosbaum Maranke, Ballroom,Russell Hilton Atlanta.Green, David Kircher, Guo Chen, Michael Davies, Allie Grossmann, MonikaI Koster, Ettinger, Laura Hoaglin, Hong-An Bifeng Truong, Gao, KennethMariela L Jones,Pauli, Sofia Dennis V. R Gearty, Roop and Abul K. Matthew VanBrocklin and Sheri Holmen. Salt Lake City, UT; Austin, MN AbbasDavid and Norris. Michael Aurora, David CO. Rosenblum. San Francisco, CA. + + 001 RON2315:and Houston, A novel TX. human biologic for the topical treatment of psoriasis. 017642 QuantificationTyrosinase targeting of CD69 CD103self-delivering skin TRM RNAi cells compounds.in chronic atopic Melissa dermatitis. Maxwell, 626 ThomasPhenformin Gadek as. Portola a therapeutic Valley, CA. adjunct for melanoma. Fiona M Shaw, SeoHyeongKatherine KIMHolton,, Chang James Ook Cardia, Park, JungLakshmipathi U Shin, Ji Pandarinathan,Yeon Noh, Shan MichaelJin, 002* BlockadeLewis C Cantleyfor CD155-TIGIT and Jonathan interaction Hale Zippin. is an Atlanta,effective GA andtherapy New for York, NY. HeminByrne Lee, and Jungsoo Karen Bulock. Lee, Thomas Marlborough, S. Kupper MA. and Kwang Hoon Lee. Seoul, 627 melanoma.MicroRNA Takashiapproach Inozume to target, Tomonori collagen Yaguchi, recycling, Yutaka cellular Kawakami senescence and 643 KoreaDifferences (the Republic in patient of) and and Boston, tumor MA. characteristics in amelanotic vs. Shinjiand melaninShimada. production Chuo, Japan in and vitro. Shinjyuku, Karine Cucumel Japan. , Ludivine Mur, Florian 018* Sharedpigmented VH1-46 melanomas. antibody geneLauren usage Christene in pemphigus Strazzulla vulgaris, Xiaoxue predicts Li, Lana 003 Migratorylabarrade, DC Catherine temper subcutaneousGondran, Gilles immunity Oberto, Yolene through Ferreira key tolerance and Nouha antibodyTong, Sandra cross-reactivity J Lee and Caroline to desmoglein C Kim. New 3 and York, rotavirus NY; Los Angeles,VP6. Michael CA and pathways.Domloge. Niroshana Sophia Antipolis, Anandasabapathy France. , Christopher Nirschl, Yong Liu, JeffreyBoston, Tejada MA. Cho, Christoph Ellebrecht, Christoph Matthias Hammers, 628 ShamimPost-translational Mollah, Rachel mechanisms E. Feder, Pinru regulate Wu, fn14Peter expressionSage and Arlene and signaling H in 644* GopalInhibition Sapparapu, of histone James deacetylaseCrowe and Aimee3 overcomes S Payne. BRAF-inhibitor Philadelphia, PAresistance. and Sharpe.melanoma. Boston, Matthew MA and SNew Hayden York,, Kristen NY. M Beck. New York, NY. Nashville,Xiao-Qi WangTN. , Antonio Velez, Chelsea St. Claire and Amy S. Paller. 004629 RationalemTOR and and PKM2 design are constitutivelyof a novel dendritic up-regulated cell targeted in humanvaccine melanomafor basal 019* NextChicago, generation IL. T cell receptor sequencing reveals complex T cell cellcells carcinoma. but not in Karyn melanocytes Haitz, Steven Alfredo R Barthel, Gonzalez Yong, Jeanine Liu, Christopher Justiniano, Ryan 645 dynamicsXPA-induced in Alopecia autophagy Areata promotes . Annemieke cisplatin de Jong resistance, Luzhou in Xing, melanoma Ali Nirschl,Garrity, Ervin Yali CuiEpstein and Yinshengand Niroshana Wan. Anandasabapathy.Providence, RI and Boston, Xi’an, China. MA and Jabbari,cells. Chunying Zhenpeng Li Dai,, Rui Vera Ge, LinH Price, Liu and Madeleine Tianwen Duvic, Gao. Xi’an, David China. Norris, 630 Oakland,Circadian CA. rhythm of human tyrosinase. Earl C Goyarts, Nadine Pernodet. 646* MariaMSX1-induced Hordinsky, neuralJulian Mackay-Wiggan, crest-like reprograming Raphael promotes Clynes and melanoma Angela 005 AnMelville, ex vivo NY.skin model that combines topical skin penetration and Th17 Christiano.progression. New Mizuho York, Fukunaga-KalabisNY; San Francisco, , CA;Markus Houston, Heppt, TX; Joshua Denver, Wang, CO and 631 stimulation.Characteristic Mary comparison Bedard, Steven of human Cook, Leandromelanoma Santos, cell lines Jessica derived Neil, from Minneapolis,Denitsa Hristova, MN. Zhi Wei, Martin Irmler, Carola Berking, Robert Besch, Carlosprimary Eduardo and metastatic Peredo, Susan sites H Xiaofeng Smith, Javier Lin, David Cote-Sierra Fiore, Pauland JonThompson, Lenn. 020 CalcitoninJohannes gene-related Beckers, Frank peptide J Rauscher, (CGRP) David induces E Fisher endothelial and Meenhard cells (EC) Herlyn. to ResearchJane K Goodrich, Triangle Park, Tatyana NC. Yufit, Polly Carson and Vincent Falanga. Boston, biasPhiladelphia, Langerhans PA; cell Munich, (LC) antigen Germany; presentation Newark, NJ; towards Neuherberg, a Th17 Germany response MA. throughand Boston, induction MA. of soluble mediators. Wanhong Ding, Lori L Stohl, 006 Immunomodulatory effects of AM1030, a topical 5-HT2B receptor 632 antagonistEffects of in MAPKdevelopment inhibition for onatopic glucose dermatitis. uptake inNiklas melanoma Palmqvist are, Maxlargely 647 JohnMeasurement A Wagner, Linghui of skin Xupigmentation and Richard Davidusing Granstein.a chromameter New York,in a NY. Siller,secondary Anders to Sjödin, alterations Helena in Arozenius, cellular Christinamorphology Wenglén, . Nicholas Anna-Carin Theodosakis , 021* Elevated3-dimensional thymic stromalepidermal lymphopoietin model containing expression functional in the melanocytesskin blocks Ryde,Matthew Lars Pettersson, A Held, Alexander Cecilia Klint,Marzuka Anna and Pramhed, Marcus AnnaBosenberg. Löfdahl Newand Haven, breastMichael carcinogenesis. Allen Bachelor Shadmehr, Bridget BreyfogleDemehri, Trevorand Mitchell J Cunningham, Klausner. Sindhu Ashland, GunillaCT. Ekström. Lund, Sweden. Manivasagam,MA. Melissa Meyer, David Denardo, Raphael Kopan and Wayne 007633 PhenotypicCorrelation analysis of insulin-like of dendritic growth cells factor infiltrating II mRNA-binding a spontaneous protein 3model (IMP- 648 Yokoyama.Strategic St.use Louis, of BCL-2 MO inhibitorsand Cincinnati, to target OH. melanoma cells and of3) basal and highcell carcinoma. mobility group Christopher AT-hook Nirschl 2 (HMGA2), Yong Liu,expressions Pinru Wu, in Karyn human 022 Topicalmelanoma application initiating of eupatilin cells. Nabanita ameliorates Mukherjee atopic, Chung-Wai dermatitis-like Shiau, Yan skin Lu, Haitzmelanoma. and Niroshana Chia-Yu Anandasabapathy. Chu, Yi-Shuan Sheen, Boston, Chih-Chun MA. Yeh and Shiou-Hwa lesionsAdam of R NC/NgaAlmeida, mice. Josianna Young V Schwan, Min Park Yuchun, Ji Hyun Luo, Lee, Mayumi Ye Jin Lee Fujita, and StevenJun 008 PotentialJee. Taipei, mechanisms Taiwan. for loss of hair follicle immune privilege in youngRobinson, Lee. Seoul, William Korea Robinson, (the Republic David Norris of). and Yiqun G Shellman. Aurora, + 634* patientsMultigene with epigenetic alopecia areata signature following is a prognostic hepatitis Bmarker vaccination. in melanoma. 023 CD8COαα and T Taipei,cells contribute Taiwan. to lichen planus independence of LAMP1- ChristopherGoran Micevic Richardson, Viswanathan, Elaine Muthusamy, Gilmore and RichardBrian Poligone. Scolyer andRochester, Marcus NY. 649 meditatedThe adverse degranulation. correlation Bing of primary Li, Xiuwen cilia Sun in andmelanoma Gang Wang. is likely Xi’an, 009* CCL17Bosenberg. attenuates New Haven,tumor immunityCT and Sydney, by increasing Australia. regulatory T cells and China.independent of proliferation and cell cycle progression . Elizabeth R 635* Th2Delayed cells while cyclobutane decreasing pyrimidine myeloid-derived dimers induced suppressor by chemiexcited cells in tumor 024 ImmunomodulatorySnedecor, Clifford effectsSung, Alejandra of nanoparticles Moncayo, Brookeon the contactRothstein, Daniel microenvironment.melanin derivatives Makoto long afterSugaya ,UV Sohshi exposure. Morimura, Sanjay Premi Tomonori, Silvia Oka, hypersensitivityMockler, Marcia response Tonnesen, in EvanC57BL/6 Jones, hairless Mayumi mice. Fujita, Samreen Richard Jatana August, HirakuWallisch, Suga, Camila Tomomitsu Mano, Miyagaki, Adam Weiner, Yuichiro Antonella Tsunemi, Bacchiocchi, Yoshihide Asano,Kazumasa BrianClark, C PalmerKenneth and R ShroyerLisa A DeLouise. and Jiang Rochester, Chen. Stony NY. Brook, NY; Medford, MA; YayoiWakamatsu, Tada, Takafumi Etelvino Kadono Bechara, and Ruth Shinichi Halaban, Sato. ThierryTokyo, Japan.Douki and Douglas 025 CapturingNorthport, functional NY and Denver, conservation CO. between human skin and mouse DC 010 DistinctiveE. Brash. New downmodulation Haven, CT; Sao Paulo, of plasmacytoid Brazil; Toyoake, dendritic Japan; cell São by Paulo, vitamin 650 systemsSwitching for generatingthe enemy: Thebetter anti-leprotic vaccines. Eynav clofazimine Klechevsky displays. Saint Louis, anti- D3Brazil analogue and Grenoble, in its interferon- France.α production and chemotactic activity. MO.melanoma activity through induction of genotoxic stress. Angela L 636* TakahiroOncogene Suzuki starvation, Yoshiki Tokura.via selective Hamamatsu, CDK7 inhibition: Japan. A novel approach for 026* HumanDavis, skinSophia is protected L Park, Hui by Li, four Shuxi functionally Qiao, Joshua and D Williamsphenotypically and Georg T 011** Atargeting wave of regulatory traditionally T cells undruggable into neonatal oncogenic skin mediates molecules tolerance in melanoma. to discreteWondrak. populations Tucson, AZ. of resident and recirculating memory T cells. Rei commensalPhilip Eliades microbes, David Michael. Tiffany Miller, C Scharschmidt Michael ,Taylor, Kimberly Raj SKumar, Vasquez, Nicholas Hong- 651* WatanabeIL-23 prevents, Ahmed melanoma Gehad, Chao development Yang, Laura through Campbell, multiple Jessica Emberleymechanisms. AnKwiatkowski, Truong, Sofia Tinghu V. Gearty, Zhang, MarielaRichard L APauli, Young, Audrey Nathanael Nosbaum, S Gray Michael and Teague,Tahseen Victor H. Nasti Huang,, Mohammad Tiago R Matos, Athar, Thomas Laura Timares S. Kupper and and Craig Rachael A Elmets. Otto,Hensin James Tsao. J Boston,Moon, AbulMA andK. Abbas, Cambridge, Michael MA. A Fischbach and Michael Clark.Birmingham, Boston, MA. AL. 637* DavidSex steroids Rosenblum. regulate San Francisco,human pigmentation CA; Bethesda, through MD and non-classical Charlestown, 027652* NovelDeregulation STAT3 inhibitor of chemotactic LLL12 significantly signals, leukocytereduces IL-17, recruitment, IL-22, and and IFN- MA.receptors. Christopher Natale, Todd William Ridky. Philadelphia, PA. gammaimmunity mRNA in segmentalexpression vitiligo. in psoriatic Ahmed PBMCs. Fawzy Justin Rezk , MoetazG Hastings El-Domyati,, Xiaoli 012638 KeratinFisetin 17potentiates enhances thethe chemotaxis anti-invasive of neutrophilsand anti-metastatic through regulating effects of Zhang,Wael JiayuhHosam Lin, El-Din, Chenglong Jouni Uitto, Li and HenryOlga Igoucheva K Wong. Columbus,and Vitali Alexeev. OH. Minia, chemokinesorafenib inCXCL1 BRAF-mutated secretion inmelanoma. keratinocytes Harish via C PalPI3k/AKT/NF-, Ariana Cκ Diamond,B 028* GILT-mediatedEgypt and Philadelphia, processing PA. of a self and melanoma antigen in thymic pathway.John C Kappes, Er-Le Dang Craig, Liang A Elmets Jin, Chang-xuand Farrukh Han, Afaq. Bing Birmingham, Li, Man Jiang AL. and 653 epithelialEvaluation cells of promotes a topical deletionformulation and regulatorycontaining T myristylcells. Karen nicotinate Taraszka 639 GangP2X7/PANX1 Wang. Xi’an, inhibition China. decreases melanoma proliferation and Hastingsfor modulating, Matthew melaninRausch, productionTodd C. Metzger, in comparison Michael Waterfield,to a formulation Jessica 013* Contributionsdifferentiation of in skin vitro resident and decreases and recirculating tumor growth memory in vivo. T cells Jenna to Cortezcontaining and Mark hydroquinone S. Anderson. . Smitha Phoenix, Rao AZ. Newand SanYork, Francisco, NY. CA. depigmentationBordelon, Samantha in vitiligo. L Schneider, Jillian Richmond Andrew Louis, Mehdi Ross, Rashighi, Mark Eller Priti and AgarwalJames Michaeland John Grichnik. E Harris. Miami, Worcester, FL and MA. Bronx, NY.

Notes:Notes:

1 23 96 PPosteroster PPresentationsresentations // aabstractbstract ttitlesitles

Adaptive Immunity & Vaccination 014654 Acne4’-Bromo-resveratrol, vaccines targeting a newsecretory small moleculeCAMP factor inhibitor of Propionibacterium of SIRT3, imparts 665 Alterations of vitamin A metabolism and signaling in central, centrifugal, All orals [designated with an asterisk (*)] listed below are presented in the acnes.anti-proliferative Chun-Ming Huang effects. San and Diego, causes CA. metabolic reprograming of human cicatricial alopecia patients. Liye Suo, Wilma F Bergfeld, Natasha Adaptive Immunity & Vaccination Minisymposium on Saturday, May 9, 2015, 015* Identifyingmelanoma cells.Merkel Jasmine polyomavirus-specific George, Minakshi Nihal,CD4+ andChandra CD8+ KT-cells Singh inand Mesinkovska and Helen B Everts. Cleveland, OH and Columbus, OH. from 12:30-3:30 pm in Salon D, Hilton Atlanta. Orals designated by two asterisks MerkelNihal Ahmad. cell carcinoma Madison, patients’ WI. tumor-infiltrating lymphocytes. Dafina 666 Human hair follicle epithelial stem cells undergo epithelial- (**) will be presented during a Plenary Session. Orals designated by three 655 Ibrani105F ,is Jayasri a novel G immunoadaptiveIyer, Natalie Vandeven, treatment Natalie candidate Miller, Olga for Afanasiev, melanoma mesenchymal transition (EMT) in primary cicatricial alopecia: Lessons asterisks (***) will be presented during the Interdisciplinary Spotlight: Skin Davidthat induces Koelle and apoptosis Paul Nghiem. and the Seattle, secretion WA. of pro-inflammatory IL-6. Gail from lichen planopilaris. Hisayoshi Imanishi, David Ansell, Matthew Cancer Minisymposium on Friday, May 8, 2015, from 2:00 – 5:00 pm in the Grand 016* RegulatoryNaughton, EmmettT cells facilitate Pinney, cutaneousChristian woundPosch, Aline healing. Betancourt Audrey Nosbaumand Mayra , Harries, Norbert Sepp, Tamas Biro, Daisuke Tsuruta, Christopher M Ward Ballroom, Hilton Atlanta. MonikaMontes-Camacho. Ettinger, SanHong-An Diego, Truong, CA and MarielaSan Francisco, L Pauli, SofiaCA. V. Gearty, Abul K. and Ralf Paus. Manchester, United Kingdom; Innsbruck, Austria; Osaka, Abbas and Michael David Rosenblum. San Francisco, CA. Japan and Debrecen, Hungary. + + 001 RON2315: A novel human biologic for the topical treatment of psoriasis. 017 Quantification of CD69 CD103 skin TRM cells in chronic atopic dermatitis. 667 Electrophysiological and immunohistological characterization of Thomas Gadek. Portola Valley, CA. SeoHyeong KIM, Chang Ook Park, Jung U Shin, Ji Yeon Noh, Shan Jin, TMEM16A isoforms in human sweat glands. Torsten Ertongur-Fauth, 002* Blockade for CD155-TIGIT interaction is an effective therapy for Skin &Hemin Hair Lee, Developmental Jungsoo Lee, Thomas S. Biology Kupper and Kwang Hoon Lee. Seoul, Andrea Brueggemann, Christina Jost and Daniela Kulichová. Zwingenberg, melanoma. Takashi Inozume, Tomonori Yaguchi, Yutaka Kawakami and All oralsKorea [designated (the Republic with an of) asterisk and Boston, (*)] listed MA. below are presented in the Skin Germany and Munich, Germany. Shinji Shimada. Chuo, Japan and Shinjyuku, Japan. 018*& Hair DevelopmentalShared VH1-46 Biologyantibody Minisymposium gene usage in on pemphigus Thursday, vulgarisMay 7, 2015,predicts from 668* Hdac1 and hdac2 are required for maintenance and survival of 003 Migratory DC temper subcutaneous immunity through key tolerance 2:00-5:00antibody pm in Salon cross-reactivity D, Hilton Atlanta. to desmoglein Orals designated 3 and rotavirus by two asterisks VP6. Michael (**) embryonic and adult epidermal stem cells. Matthew LeBoeuf, Fang Liu, pathways. Niroshana Anandasabapathy, Christopher Nirschl, Yong Liu, will be presentedJeffrey Tejada during Cho a, PlenaryChristoph Session. Ellebrecht, Orals Christoph designated Matthias by three Hammers,asterisks Xinyi Zhao, Eric Olson and Sarah Millar. Philadelphia, PA and Dallas, TX. Shamim Mollah, Rachel E. Feder, Pinru Wu, Peter Sage and Arlene H (***) willGopal be presented Sapparapu, during James the Crowe Interdisciplinary and Aimee S Spotlight: Payne. Philadelphia, Skin Cancer PA and 669 Keratinocytes devoid of DLX3 initiate psoriasis-like inflammation in Sharpe. Boston, MA and New York, NY. MinisymposiumNashville, on TN. Friday, May 8, 2015, from 2:00 – 5:00 pm in the Grand mice. Jin-Chul Kim, Gaku Nagato, Youichi Ogawa, Mark C Udey and Maria 004 Rationale and design of a novel dendritic cell targeted vaccine for basal 019*Ballroom, Next Hilton generation Atlanta. T cell receptor sequencing reveals complex T cell Morasso. Bethesda, MD. cell carcinoma. Karyn Haitz, Steven R Barthel, Yong Liu, Christopher dynamics in Alopecia Areata . Annemieke de Jong, Luzhou Xing, Ali 670 Preventing radiation-induced hair loss by augmenting spontaneous Nirschl, Ervin Epstein and Niroshana Anandasabapathy. Boston, MA and 656 Jabbari,Human Zhenpengfacial sebaceous Dai, Vera glands H Price, contain Madeleine the enzymes Duvic, thatDavid synthesise Norris, anagen repair through modulating wnt signaling. Wen-Yen Huang, Hsien- Oakland, CA. Mariaprostaglandin Hordinsky, F2 αJulian and prostamide Mackay-Wiggan, F2α and Raphael the receptors Clynes andto respond Angela to Yi Chiu, Chih-Chieh Chan and Sung-Jan Lin. Taipei, Taiwan. 005 An ex vivo skin model that combines topical skin penetration and Th17 Christiano.bimatoprost. New Mohammad York, NY; SanShalbaf Francisco,, Theresa CA; Street, Houston, Neil TX; J Poloso, Denver, Jenny CO and W 671** Inducing hair follicle neogenesis with 3 protein factors. Sung-Jan Lin, stimulation. Mary Bedard, Steven Cook, Leandro Santos, Jessica Neil, Minneapolis,Wang, David MN.Woodward and Valerie Randall. Bradford, United Kingdom Sabrina Mai-Yi Fan, Chien-Mei Yen, Szu-Hua Pan and Yu-Ju Chen. Taipei, Carlos Eduardo Peredo, Susan H Smith, Javier Cote-Sierra and Jon Lenn. 020 Calcitoninand Irvine, gene-related CA. peptide (CGRP) induces endothelial cells (EC) to Taiwan. Research Triangle Park, NC. 657 biasA comparison Langerhans of cell methods (LC) antigen of anagen presentation synchronization towards in aan Th17animal response 672 Novel diagnostic test predicts mean change in hair counts in female throughmodel for induction alopecia. ofAlexandra soluble Cristinamediators. VillasanteWanhong, Vanessa Ding, Lori Alejandra L Stohl, Petit, androgenetic alopecia patients treated with topical minoxidil. John 006 Immunomodulatory effects of AM1030, a topical 5-HT2B receptor antagonist in development for atopic dermatitis. Niklas Palmqvist, Max JohnNatalie A Wagner, Yin, George Linghui Elgart, Xu andLawrence Richard Schachner David Granstein. and Joaquin New Jimenez. York, NY. McCoy, Andy Goren, Janet Roberts and Nisha Desai. Irvine, CA and Siller, Anders Sjödin, Helena Arozenius, Christina Wenglén, Anna-Carin 021* ElevatedNew York, thymic NY and stromal Miami, lymphopoietin FL. expression in the skin blocks Portland, OR. Ryde, Lars Pettersson, Cecilia Klint, Anna Pramhed, Anna Löfdahl and 658 breastKnockdown carcinogenesis. of Sulf2 causes Shadmehr hair loss Demehri in obese, Trevor mice J Cunningham,fed a fast food Sindhu diet. 673* Alopecia areata is transferred via activated T-lymphocytes. Eddy Hsi Gunilla Ekström. Lund, Sweden. Manivasagam,Jeannette M. MelissaOlazagasti Meyer,, Catherine David D. Denardo, Moser, Tae Raphael Hyo Kim, Kopan Anuradha and Wayne Chun Wang, Mohsen Khosravi-Maharlooei, Reza Jalili, Richard Yu, Aziz 007 Phenotypic analysis of dendritic cells infiltrating a spontaneous model Yokoyama.Krishnan and St. LewisLouis, R.MO Roberts. and Cincinnati, Rochester, OH.MN. Ghahary, Jerry Shapiro and Kevin John McElwee. Vancouver, Canada. of basal cell carcinoma. Christopher Nirschl, Yong Liu, Pinru Wu, Karyn 022659 TopicalFollistatin application and secreted of eupatilin frizzled-related ameliorates protein atopic 1, OVOdermatitis-like homolog-like skin 1- 674*** The role of dermal wnt activation in hair follicle development and Haitz and Niroshana Anandasabapathy. Boston, MA. lesionsregulated of NC/Ngagenes, are mice. important Young Min for Parkhair ,follicle Ji Hyun neogenesis. Lee, Ye Jin Lee Young-Kwan and Jun carcinogenesis. Peggy Myung, Thomas Yang, Panteleimon Rompolas and 008 Potential mechanisms for loss of hair follicle immune privilege in youngSung, Soon-SunLee. Seoul, Bak, Korea Moon (the Kim Republic and Jung-Chul of). Kim. Daegu, Korea (the Valentina Greco. New Haven, CT. + patients with alopecia areata following hepatitis B vaccination. 023 CD8Republicαα T of). cells contribute to lichen planus independence of LAMP1- 675 The role of regulatory T-cells in hair follicle cycling. Niwa Ali, Hong-An Christopher Richardson, Elaine Gilmore and Brian Poligone. Rochester, NY. 660 meditatedStimulatory degranulation. effect of pseudoceramide Bing Li, Xiuwen onSun hair and growth Gang Wang.through Xi’an, Truong, Abul K. Abbas and Michael David Rosenblum. San Francisco, CA. 009* CCL17 attenuates tumor immunity by increasing regulatory T cells and China.intracellular sphingolipids signaling. Jong Hwan Bae, Bu Man Park, Dae 676 Enhancing hair follicle regeneration by microthermal injury. Yueh-Feng Th2 cells while decreasing myeloid-derived suppressor cells in tumor 024 ImmunomodulatoryHwan Kim, Kyong Oh effects Shin, Seung of nanoparticles Phil Hong, Hyun on Jongthe contactKim, Sung Ku Ahn Wu, Sabrina Mai-Yi Fan and Sung-Jan Lin. Taipei, Taiwan. microenvironment. Makoto Sugaya, Sohshi Morimura, Tomonori Oka, hypersensitivityand Se Kyoo Jeong. response Daejeon, in KoreaC57BL/6 (the hairless Republic mice. of); Samreen Cheongju, Jatana Korea, 677 Apoptotic signals increase during catagen-like changes in hair follicles Hiraku Suga, Tomomitsu Miyagaki, Yuichiro Tsunemi, Yoshihide Asano, Brian(the Republic C Palmer of); and Cheonan, Lisa A DeLouise. Korea (the Rochester, Republic NY. of); Seoul, Korea (the confirming follicle organ culture’s exciting new potential as a human in Yayoi Tada, Takafumi Kadono and Shinichi Sato. Tokyo, Japan. 025 CapturingRepublic of) functional and Wonju, conservation Korea (the Republic between of). human skin and mouse DC vitro catagen model. Heero Najeeb Rahman, Nilofer Farjo, Bessam Farjo 010 Distinctive downmodulation of plasmacytoid dendritic cell by vitamin 661 systemsSystematic for generatinganalyses for betterskin, hair, vaccines. and Eynavnail abnormalities Klechevsky. Saint in TheLouis, Jackson and Valerie Randall. Bradford, United Kingdom and Manchester, United 2 D3 analogue in its interferon-α production and chemotactic activity. MO.Laboratory’s KOMP knockout mouse program. John Paul Sundberg, C. Kingdom. Takahiro Suzuki, Yoshiki Tokura. Hamamatsu, Japan. 026* HumanHerbert skin Pratt, is protected Stephen A.by fourMurray, functionally Kathleen A Silva,and phenotypicallyVictoria E Kennedy, 678 Bimatoprost alters prostaglandinand prostamide synthesis inhuman 011** A wave of regulatory T cells into neonatal skin mediates tolerance to discreteLloyd E. populationsKing and Soheil of Sresident Dadras. andBar Harbor,recirculating ME; Nashville, memory TN T cells.and Rei scalp hair follicles. Valerie Randall, Heero Najeeb Rahman, Karzan commensal microbes . Tiffany C Scharschmidt, Kimberly S Vasquez, Hong- WatanabeFarmington,, Ahmed CT. Gehad, Chao Yang, Laura Campbell, Jessica Emberley Khidhir, Omid Shalbaf, Nilofer Farjo, Bessam Farjo, Neil J Poloso, Jenny W An Truong, Sofia V. Gearty, Mariela L Pauli, Audrey Nosbaum, Michael 662 Teague,Wnt/β-catenin Victor Huang, signaling Tiago drives R Matos, epidermal Thomas fate S. specification Kupper and Rachael in human Wang, David Woodward and Steve Picksley. Bradford, United Kingdom; Otto, James J Moon, Abul K. Abbas, Michael A Fischbach and Michael Clark.embryonic Boston, stem MA. cells. Samantha Lin, Kathryn A. Rosowski, Amanda Manchester, United Kingdom and Irvine, CA. David Rosenblum. San Francisco, CA; Bethesda, MD and Charlestown, 027 NovelFarrell, STAT3 Ana Tadeu, inhibitor Cassandra LLL12 significantly O’Curran and reduces Valerie IL-17, Horsley. IL-22, New and Haven, IFN- 679 Spatial trans-interactions between lineage-specific gene loci are MA. gammaCT. mRNA expression in psoriatic PBMCs. Justin G Hastings, Xiaoli required for differentiation of the stratified epithelium. Andrei 012 Keratin 17 enhances the chemotaxis of neutrophils through regulating 663 Zhang,Dynein Jiayuh is necessary Lin, Chenglong for intracellular Li and Henry transport K Wong. of both Columbus, nutrients OH. and Mardaryev, Janina Baer, Krzysztof Poterlowicz, Jana Rudolf, Igor chemokine CXCL1 secretion in keratinocytes via PI3k/AKT/NF-κB 028* GILT-mediatedautophagosomes processing in human of dermala self and fibroblasts. melanoma Yong antigen Zhuang in, Russellthymic Malashchuk, Valentina Rapisarda, Vinod Kumar, Andrey Sharov, pathway. Er-Le Dang, Liang Jin, Chang-xu Han, Bing Li, Man Jiang and epithelialWyborski, cells Siming promotes Chen, Raaj deletion P Khusial and and regulatory John Lyga. T cells. Suffern, Karen NY.Taraszka Joanne Yarker, Michael Fessing, Terumi Kohwi-Shigematsu, Vladimir Gang Wang. Xi’an, China. 664* HastingsDynamic, Matthewinteractions Rausch, between Todd nailC. Metzger,epithelium Michael and digitWaterfield, bone by JessicaWnt A. Botchkarev and Thomas Magin. Bradford, United Kingdom; Leipzig, 013* Contributions of skin resident and recirculating memory T cells to Cortezsignaling. and Makoto Mark S. TakeoAnderson., Christopher Phoenix, S. AZ Hale and and San Mayumi Francisco, Ito. CA. New York, Germany; Boston, MA and San Francisco, CA. depigmentation in vitiligo. Jillian Richmond, Mehdi Rashighi, Priti NY. Agarwal and John E Harris. Worcester, MA. Notes: Notes:

97 1 24 PPosteroster P Presentationsresentations / /a abstractbstract t titlesitles

Adaptive680* Polycomb Immunity repressive complex& Vaccination maintains epidermal progenitors by 014696 AcneGenetic vaccines determinants targeting secretoryof eccrine CAMPsweat factorgland ofdensity Propionibacterium in the mouse. All orals [designatedrepressing keywith Merkel an asterisk cell differentiation (*)] listed below are genes. presented Elena Ezhkova in the, Evan acnes.Bruce Chun-Ming Morgan, Yana Huang Kamberov. San Diego, and CA.Clifford Tabin. Boston, MA. AdaptiveBardot Immunity and Carolina& Vaccination Perdigoto. Minisymposium New York, NY. on Saturday, May 9, 2015, 015* Identifying Merkel polyomavirus-specific CD4+ and CD8+ T-cells in from681* 12:30-3:30 Serum responsepm in Salon factor D, Hilton (SRF) Atlanta.regulates Orals the designateddevelopment by andtwo asterisks Merkel cell carcinoma patients’ tumor-infiltrating lymphocytes. Dafina (**) will becyclic presented regeneration during aof Plenary the hair Session. follicle, Orals and functionsdesignated inby epidermalthree Ibrani, Jayasri G Iyer, Natalie Vandeven, Natalie Miller, Olga Afanasiev, asterisks (***)development will be presented in a stage-specific during the Interdisciplinarymanner. Tatiana EfimovaSpotlight:, Congxing Skin Lin, TissueDavid Regeneration Koelle and Paul Nghiem. & Seattle,Wound WA. Healing Cancer MinisymposiumAaron Koppel, onAlexi Friday, Kiss andMay Liang 8, 2015, Ma. from St. Louis, 2:00 MO.– 5:00 pm in the Grand 016*All oralsRegulatory [designated T cells with facilitate an asterisk cutaneous (*)] listed wound below healing. are presented Audrey inNosbaum the , Ballroom,682* Inhibition Hilton Atlanta. of JAK-STAT signaling promotes hair growth. Sivan Harel, Claire TissueMonika Regeneration Ettinger, & WoundHong-An Healing Truong, Minisymposium Mariela L Pauli, on Sofia Saturday, V. Gearty, May 9,Abul K. Higgins, Jane E Cerise, James C Chen, Zhenpeng Dai, Raphael Clynes and 2015, Abbasfrom 12:30-3:30 and Michael pm David in Salon Rosenblum. E, Hilton SanAtlanta. Francisco, Orals CA.designated by two + + 001 RON2315:Angela Christiano. A novel human New York,biologic NY. for the topical treatment of psoriasis. 017asterisks Quantification (**) will be presented of CD69 CD103 during skin a Plenary TRM cells Session. in chronic Orals atopic designated dermatitis. by 683 ThomasSexual Gadekdimorphism. Portola in Valley,human CA. scalp skin. James Chen, Gina Marie three asterisksSeoHyeong (***) KIM will, Chang be presented Ook Park, during Jung U the Shin, Interdisciplinary Ji Yeon Noh, Shan Spotlight: Jin, Skin 002* BlockadeDeStefano for and CD155-TIGIT Angela Christiano. interaction New is anYork, effective NY. therapy for CancerHemin Minisymposium Lee, Jungsoo on Lee, Friday, Thomas May 8,S. Kupper2015, from and 2:00Kwang – 5:00 Hoon pm Lee. in Seoul,the Grand 684 melanoma.Prostaglandin Takashi D2 (PGD2)Inozume enhances, Tomonori testosterone Yaguchi, Yutaka metabolism Kawakami in primaryand Ballroom,Korea Hilton (the Atlanta.Republic of) and Boston, MA. Shinjihuman Shimada. keratinocytes Chuo, Japan possibly and Shinjyuku,via upregulation Japan. of aldo-keto reductase 018* Shared VH1-46 antibody gene usage in pemphigus vulgaris predicts 003 Migratory1C3 (AKR1C3) DC temper expression. subcutaneous Alon Mantel immunity, Alice Pthrough Pentland key and tolerance Meena 697**antibody Nesprin-2 cross-reactivity declines during to skin desmoglein aging and 3 itsand loss rotavirus negatively VP6. Michael impacts pathways.Katdare. Hampton, Niroshana VA; Anandasabapathy Rochester, NY and, Christopher Norfolk, VA. Nirschl, Yong Liu, Jeffreyfibroblast Tejada and Cho keratinocyte, Christoph Ellebrecht, behaviorin Christoph vitro. Robert Matthias Maidhof Hammers,, Ying Chen, 685* ShamimWnt/β -cateninMollah, Rachelsignaling E. Feder,marks Pinruself-renewing Wu, Peter stem Sage cells and inArlene multiple H GopalUma Sapparapu, Santhanam James and John Crowe Lyga. and Suffern, Aimee S NY.Payne. Philadelphia, PA and Sharpe.epithelial Boston, tissues MA . andSarah New Millar York,, Mingang NY. Xu, Jeremy Horrell, Heather 698 Nashville,Interferon- TN.γ (IFN-γ) impedes wound healing by slowing keratinocyte 004 RationaleGochnauer, and Jiawei design Cui, of Melinda a novel Snitow,dendritic Tien cell Peng targeted and Edward vaccine Morrisey. for basal 019* Nextmigration generation through T cell the receptor upregulation sequencing of SHIP-2reveals and complex phospho-cofilin. T cell cellPhiladelphia, carcinoma. PA. Karyn Haitz, Steven R Barthel, Yong Liu, Christopher dynamicsChanna Gin OvitsAlopecia, Jie Chen,Areata Juana . Annemieke Gonzalez, de Dix Jong P. ,Poppas, Luzhou DianeXing, Ali Felsen and 686 Nirschl,Alopecia Ervin areata Epstein and and atopic Niroshana dermatitis Anandasabapathy. share common Boston, Th2 andMA IL-23 and Jabbari,John A. Zhenpeng Carucci. NewDai, VeraYork, H NY. Price, Madeleine Duvic, David Norris, Oakland,inflammatory CA. pathways, with implications for targeted therapeutics. 699 MariaVitamin Hordinsky, D and calciumJulian Mackay-Wiggan, regulation of epidermalRaphael Clynes wound and healing. Angela Dan 005 AnEmma ex vivo Guttman-Yassky skin model that, Shinji combines Noda, topicalAnjali Shroff, skin penetration Yasaman Mansouri,and Th17 Christiano.Bikle, Chia-Ling New York,Tu and NY; Yuko San Oda.Francisco, San Francisco, CA; Houston, CA. TX; Denver, CO and stimulation.Judilyn B Fuentes-Duculan, Mary Bedard, Steven Avner Cook, Shemer, Leandro Mayte Santos, Suarez-Farinas Jessica Neil, and 700* Minneapolis,Reconstitution MN. of three-dimensional skin composed of keratinocytes, CarlosJames Eduardo G Krueger. Peredo, New SusanYork, NYH Smith, and Tel-Hashomer, Javier Cote-Sierra Israel. and Jon Lenn. 020 Calcitoninfibroblasts gene-related and melanocytes peptide induced (CGRP) inducesfrom Muse endothelial human pluripotentcells (EC) to 687* ResearchGorab is Triangle essential Park, for NC. dermal papilla cells to respond to hedgehog biasstem Langerhans cell. Takeshi cell Yamauchi (LC) antigen, Kenshi presentation Yamasaki, Kenichirotowards a Tsuchiyama, Th17 response signals during hair follicle formation. Jiang Chen, Ying Liu, Elizabeth R throughSaaya Koike,induction Mai Inoueof soluble and Setsuyamediators. Aiba. Wanhong Sendai, DingJapan., Lori L Stohl, 006 Immunomodulatory effects of AM1030, a topical 5-HT2B receptor antagonistSnedecor, inYeun development Ja Choi, Ning for Yang, atopic Xu dermatitis. Zhang, Yuhuan Niklas Xu, Palmqvist Yunlin Han,, Max Evan 701 JohnHigh A Wagner,glucose environmentLinghui Xu and increased Richard Davidthrombospondin-1 Granstein. New expression York, NY. in Siller,C Jones, Anders Kenneth Sjödin, R HelenaShroyer, Arozenius, Richard August Christina Clark, Wenglén, Lianfeng Anna-CarinZhang and 021* Elevatedkeratinocytes thymic stromalvia epigenetic lymphopoietin regulation: expression Metabolic in the memoryskin blocks of impaired Ryde,Chuan Lars Qin. Pettersson, Beijing, China Cecilia and Klint, Stony Anna Brook, Pramhed, NY. Anna Löfdahl and breastangiogenesis carcinogenesis. during diabeticShadmehr woundDemehri healing., Trevor Cheng-Che J Cunningham, Lan, Shu-Mei Sindhu 688 GunillaThe distal Ekström. end ofLund, the Sweden.arrector pili muscle is a potential epidermal stem Manivasagam,Huang, Ching Melissa Shuang Meyer, Wu and David Gwo-Shing Denardo, Chen. Raphael Kaohsiung, Kopan Taiwan.and Wayne 007 Phenotypiccell niche. analysisNiloufar ofTorkamani dendritic, Nicholas cells infiltrating Rufaut, Leslie a spontaneous Jones and Rodney model 702 Yokoyama.Targeted St.genetic Louis, MOalteration and Cincinnati, in hyaluronan OH. catabolism delays wound ofSinclair. basal cell Richmond, carcinoma. Australia Christopher and Melbourne, Nirschl, Yong Australia. Liu, Pinru Wu, Karyn 022 Topicalhealing application in mice. Jun of Mutoeupatilin, Andrea ameliorates Garcia, Daisuke atopic Watanabe,dermatitis-like Ajit Varki skin 689* HaitzWnt and signaling Niroshana controls Anandasabapathy. the reversible differentiationBoston, MA. of melanocyte stem lesionsand Richard of NC/Nga L Gallo. mice. Nagakute, Young Min Japan Park and, Ji HyunLa Jolla, Lee, CA. Ye Jin Lee and Jun 008 Potentialcells during mechanisms their self-renewal. for loss of Qi hair Sun follicle, Hai Hu, immune Makoto privilege Takeo, Wendy in Lee, 703* youngCollagen Lee. Seoul,XVII regulates Korea (the actin Republic dynamics of). and traction forces in motile + patientsMark M. Taketowith alopecia and Mayumi areata Ito.following New York, hepatitis NY and BKyoto, vaccination. Japan. 023 CD8keratinocytes.αα T cells contribute Sho Hiroyasu to lichen, Zachary planus Colburn independence and Jonathan of LAMP1- Jones. 690 ChristopherMHC genes Richardson associated, Elainewith alopecia Gilmore areataand Brian exhibit Poligone. diverse Rochester, and complex NY. meditatedPullman, degranulation.WA. Bing Li, Xiuwen Sun and Gang Wang. Xi’an, 009* CCL17expression attenuates patterns tumor during immunity hair follicle by increasing development regulatory in mice. T cells Alexander and 704* China.Cadherin endocytosis, adhesion, and cytoskeletal linkage cooperatively Th2Awgulewitsch cells while ,decreasing John Paul Sundberg.myeloid-derived Charleston, suppressor SC and cells Bar Harbor,in tumor ME. 024 Immunomodulatoryregulate collective effects cell migration. of nanoparticles Chantel Cadwell on the, Benjamincontact A Nanes, 691 microenvironment.3D cultures of hair Makoto follicles Sugaya on Gelfoam®, Sohshi promote Morimura, functional Tomonori recovery Oka, hypersensitivityDaniel Conway andresponse Andrew in Kowalczyk.C57BL/6 hairless Atlanta, mice. GA Samreen and Richmond, Jatana, VA. Hirakuof severed Suga, peripheralTomomitsu nerves Miyagaki, and Yuichiro the spinal Tsunemi, cord when Yoshihide transplanted Asano, 705 BrianKeloid C Palmer pathogenesis: and Lisa PotentialA DeLouise. role Rochester, of EDA NY.domain of cellular Yayoito the Tada, injury Takafumi site. Robert Kadono M. and Hoffman Shinichi, Wenluo Sato. Tokyo, Cao, Lingna Japan. Li, Sumiyuki 025 Capturingfibronectin. functional J. Andrews conservation, Jaana Marttala, between Edward human Macarak, skin and Joel mouse DC 010 DistinctiveMii, Yasuyuki downmodulation Amoh and Fang Liu. of plasmacytoidSan Diego, CA; dendriticShanghai, cell China by vitaminand systemsRosenbloom for generating and Jouni betterUitto. vaccines.Philadelphia, Eynav PA.Klechevsky. Saint Louis, D3Kanagawa, analogue Japan. in its interferon-α production and chemotactic activity. 706* MO.Paracrine regulation of wound angiogenesis through cooperation of 692 TakahiroMolecular Suzuki diagnostics, Yoshiki Tokura. in differentiation Hamamatsu, Japan. of segmental overgrowth 026* Humanepidermal skin isintegrins. protected Whitney by four M. functionally Longmate, Scottand phenotypically P. Lyons, Sridar V. 011** Asyndromes. wave of regulatory Jouni Uitto T cells, Leila into Youssefian, neonatal skinHassan mediates Vahidnezhad, tolerance T to discreteChittur, populations Livingston Vanof resident De Water and and recirculating C. Michael DiPersio. memory Albany,T cells. Rei NY and commensalBaghdadi, Amicrobes Ghaznavi, . Tiffany Q. Li and C ScharschmidtMina Tabrizi., Tehran,Kimberly Iran S Vasquez, (the Islamic Hong- WatanabeRensselaer,, Ahmed NY. Gehad, Chao Yang, Laura Campbell, Jessica Emberley AnRepublic Truong, of) Sofia and V.Philadelphia, Gearty, Mariela PA. L Pauli, Audrey Nosbaum, Michael 707 Teague,Scar from Victor minor Huang, burns: Tiago Focus R Matos, on cutaneous Thomas S. nerve Kupper destruction and Rachael and 693* Otto,Studying James hair J cycleMoon, clockAbul withK. Abbas, the aidMichael of multi-scale A Fischbach diffusion-based and Michael Clark.regeneration. Boston, MA. Vetrichevvel Thirthar Palanivelu, Siaavash Maghami, Davidmathematical Rosenblum. modeling.San Francisco, Maksim CA; Plikus Bethesda,, Ji Won MD Oh, and Qixuan Charlestown, Wang and 027 NovelShashini STAT3 Dissanayake, inhibitor LLL12 Hilary significantly Wallace, Fiona reduces Wood, IL-17, Guy IL-22, Ben-Ary, and StuartIFN- MA.Qing Nie. Irvine, CA. gammaHodgetts mRNA and expression Mark Fear. in Perth, psoriatic Australia. PBMCs. Justin G Hastings, Xiaoli 012694* KeratinThe LINC 17 complexenhances promotes the chemotaxis keratinocyte of neutrophils cell-cell throughadhesion regulating and hair 708 Zhang,Comparison Jiayuh Lin, of theChenglong transcriptomes Li and Henry of mouse K Wong. skin Columbus, derived precursors OH. and chemokinefollicle structure. CXCL1 secretion Amanda Zubek in keratinocytes, Rachel Stewart, via PI3k/AKT/NF- Kathryn A. κRosowski,B 028* GILT-mediatedSKP-derived fibroblastsprocessing ofby a RNA-Seq.self and melanomaYujie Mao, Liantigen Li. Chengdu, in thymic China. pathway.Megan King Er-Le and Dang Valerie, Liang Horsley. Jin, Chang-xu New Haven, Han, BingCT. Li, Man Jiang and 709* epithelialEpigenetic cells regulation promotes deletionof the wound and regulatory healing: the T cells.role Karenof Polycomb Taraszka Cbx4 695* GangRapid Wang. hair cycleXi’an, patternChina. breakdown during mouse development Hastingsgene in, Matthewthe epithelial Rausch, regeneration. Todd C. Metzger, Andrey SharovMichael, AndreiWaterfield, Mardaryev, Jessica 013* Contributionsrevealed with ofthe skin aid resident of mathematical and recirculating modeling. memoryJi Won OhT cells, Qixuan to CortezAhmar and Aziz, Mark Krzysztof S. Anderson. Poterlowicz, Phoenix, Tatyana AZ and Y SanSharova, Francisco, Guoliang CA. Xu and depigmentationWang, Qing Nie inand vitiligo. Maksim Jillian Plikus. Richmond Irvine,, CA.Mehdi Rashighi, Priti Vladimir A. Botchkarev. Bradford, United Kingdom; Boston, MA and Agarwal and John E Harris. Worcester, MA. Shanghai, China.

Notes:Notes:

1 25 98 PPosteroster P Presentationsresentations // aabstractbstract ttitlesitles

Adaptive Immunity & Vaccination 710014 FibroblastsAcne vaccines from targeting the elderly secretory fail to depositCAMP factor sufficient of Propionibacterium extracellular matrix 727 Long-term type 2 diabetes induces dysfunctions in epidermal All orals [designated with an asterisk (*)] listed below are presented in the toacnes. generate Chun-Ming connective Huang .tissue San inDiego, vitro. CA. Richard August Clark, Fubao Lin keratinocytes with impact on the interaction with nerve fibers in Adaptive Immunity & Vaccination Minisymposium on Saturday, May 9, 2015, 015* andIdentifying John Medamana. Merkel polyomavirus-specific Stony Brook, NY. CD4+ and CD8+ T-cells in organotypic skin models. Ludger Kolbe, Olga Reichert, Gitta Neufang, from 12:30-3:30 pm in Salon D, Hilton Atlanta. Orals designated by two asterisks 711* IRF1Merkel protein cell carcinoma levels depend patients’ on microRNA tumor-infiltrating miR-31 and reducedlymphocytes. levels Dafina Lara Terstegen, Horst Wenck and Dennis Roggenkamp. Hamburg, (**) will be presented during a Plenary Session. Orals designated by three ofIbrani IRF1, Jayasriinhibit Gkeratinocyte Iyer, Natalie Vandeven,migration. ThomasNatalie Miller,Andl, ChaseOlga Afanasiev, Taylor and Germany. asterisks (***) will be presented during the Interdisciplinary Spotlight: Skin ClaudiaDavid Koelle D Andl. and Nashville, Paul Nghiem. TN. Seattle, WA. 728 Dermal fibroblasts derived from human venous ulcers show high Cancer Minisymposium on Friday, May 8, 2015, from 2:00 – 5:00 pm in the Grand 712016* TheRegulatory pivotal roleT cells of facilitateperiostin cutaneous in RDEB scarring. wound Oliviahealing. Lai Audrey, Jon Cogan, Nosbaum Xinyi, migratory and proliferative activity in vitro. Marta Otero-Vinas, Xiaofeng Ballroom, Hilton Atlanta. Wang,Monika Yingping Ettinger, Hou, Hong-An David TimothyTruong, Woodley Mariela L andPauli, Mei Sofia Chen. V. LosGearty, Angeles, Abul K. Lin, Tatyana Yufit, Polly Carson and Vincent Falanga. Boston, MA and Vic, CA.Abbas and Michael David Rosenblum. San Francisco, CA. Spain. + + 001 RON2315: A novel human biologic for the topical treatment of psoriasis. 713017 ProlongedQuantification local vasodilation of CD69 CD103 following skin TRM topicalcells in chronicapplication atopic of dermatitis. nitric oxide 729 A novel stress-response mechanism by Hsp90α and Hsp90β to cope Thomas Gadek. Portola Valley, CA. releasingSeoHyeong nanoparticles. KIM, Chang Ook David Park, Otto Jung Schairer U Shin,, Moses Ji Yeon Tar, Noh, Pedro Shan Cabrales, Jin, with hypoxia and nutrient paucity during wound healing. Priyamvada 002* Blockade for CD155-TIGIT interaction is an effective therapy for MahanteshHemin Lee, Navati,Jungsoo Lee,Brandon Thomas Adler, S. KupperParimala and Nacharaju, Kwang Hoon Adam Lee. Friedman, Seoul, Jayaorakash, Hangming Dong, Memgchen Zou, Ayesha Bhatia, Kathryn melanoma. Takashi Inozume, Tomonori Yaguchi, Yutaka Kawakami and JoelKorea Friedman (the Republic and Kelvin of) and Davies. Boston, Bronx, MA. NY and La Jolla, CA. O’Brien, Mei Chen, David Timothy Woodley and Wei Li. Los Angeles, CA. Shinji Shimada. Chuo, Japan and Shinjyuku, Japan. 714018* TheShared guanine VH1-46 nucleotide antibody exchangegene usage factor in βpemphigus-PIX regulates vulgaris the speedpredicts of 730 Effects of diet modification on the formation of heterotopic ossification 003 Migratory DC temper subcutaneous immunity through key tolerance motileantibody keratinocytes. cross-reactivity Susan toB Hopkinsondesmoglein, Gregory3 and rotavirus Stimac andVP6. Michael Jonathan in the mutant Abcc6-/- mouse following thermal injury. Thea P Price, pathways. Niroshana Anandasabapathy, Christopher Nirschl, Yong Liu, Jones.Jeffrey Pullman, Tejada ChoWA., Christoph Ellebrecht, Christoph Matthias Hammers, Christine F Lotto, J. Andrews, Q. Li and Jouni Uitto. Philadelphia, PA. Shamim Mollah, Rachel E. Feder, Pinru Wu, Peter Sage and Arlene H 715 HumanGopal Sapparapu, skin equivalents James withCrowe perfusable and Aimee three-dimensional S Payne. Philadelphia, PA and 731* Topically delivered allogeneic mesenchymal stems cells accelerate Sharpe. Boston, MA and New York, NY. microvessels.Nashville, TN. Hasan Erbil Abaci, Zongyou Guo, Brian Gillette, Wen-han healing. Michael Lichtman, Sarah Kam, Tatyana Y Sharova, Xiaofeng Lin, 004 Rationale and design of a novel dendritic cell targeted vaccine for basal 019* Lee,Next Karl generation Gledhill, SamuelT cell receptor K Sia, Michael sequencing L Shuler reveals and complexAngela Christiano. T cell Tatyana Yufit, David Fiore, Polly Carson and Vincent Falanga. Boston, MA. cell carcinoma. Karyn Haitz, Steven R Barthel, Yong Liu, Christopher Newdynamics York, inNY Alopecia and Ithaca, Areata NY. . Annemieke de Jong, Luzhou Xing, Ali 732 Increased TSLP expression in keloids: Dose increased expression of TSLP Nirschl, Ervin Epstein and Niroshana Anandasabapathy. Boston, MA and 716 KeratinocyteJabbari, Zhenpeng progenitor Dai, Vera cells H inPrice, human Madeleine subcutaneous Duvic, David adipose Norris, tissue. promote keloid pathogenesis? Jung U Shin, SeoHyeong KIM, Ji Yeon Noh, Oakland, CA. HideoMaria IidaHordinsky,, Toshio JulianHasegawa, Mackay-Wiggan, Atsushi Sakamoto, Raphael Akino Clynes Wada, and Angela Tatsuo Shan Jin, Chang Ook Park, Ju Hee Lee, Won Jai Lee, Dong Won Lee and 005 An ex vivo skin model that combines topical skin penetration and Th17 FukaiChristiano. and Shigaku New York, Ikeda. NY; Tokyo, San Francisco, Japan. CA; Houston, TX; Denver, CO and Kwang Hoon Lee. Seoul, Korea (the Republic of) and Boston, MD. stimulation. Mary Bedard, Steven Cook, Leandro Santos, Jessica Neil, 717* RepairMinneapolis, versus MN.regeneration: Msx2 is required for epidermal competency 733 Keloid pathogenesis: Gene expression profiling in a mouse model for Carlos Eduardo Peredo, Susan H Smith, Javier Cote-Sierra and Jon Lenn. 020 duringCalcitonin wound gene-related induced follicular peptide neogenesis.(CGRP) induces Michael endothelial Warren cellsHughes (EC), to keloids. Jaana Marttala, J. Andrews, Joel Rosenbloom and Jouni Uitto. Research Triangle Park, NC. Ting-Xinbias Langerhans Jiang, Gary cell Lai, (LC) Christopher antigen presentation Schafer, Robert towards Maxson, a Th17 Randal response Philadelphia, PA. through induction of soluble mediators. Wanhong Ding, Lori L Stohl, 006 Immunomodulatory effects of AM1030, a topical 5-HT2B receptor Widelitz and Cheng-Ming Chuong. Los Angeles, CA and Tainan, Taiwan. 734* CAGE sequencing reveals MAFB as an early VEGF-C induced antagonist in development for atopic dermatitis. Niklas Palmqvist, Max 718 ImprovingJohn A Wagner, stretch Linghui mark Xupathophysiology and Richard David knowledge Granstein. by New specific York, in NY. vitro transcription factor that mediates cutaneous lymphatic vessel Siller, Anders Sjödin, Helena Arozenius, Christina Wenglén, Anna-Carin 021* models.Elevated Stephanie thymic stromal Bredif ,lymphopoietin Morgane de Tollenaere, expression Marisa in the Meloni skin blocks and differentiation and development. Michael Detmar, Lothar Dieterich, Ryde, Lars Pettersson, Cecilia Klint, Anna Pramhed, Anna Löfdahl and Carolbreast Courderot-Mazuyer. carcinogenesis. Shadmehr Epernon, Demehri France;, TrevorMilan, JItaly Cunningham, and Besançon, Sindhu Sarah Klein, Anthony Mathelier, Young-Kwon Hong and Wyeth Gunilla Ekström. Lund, Sweden. France.Manivasagam, Melissa Meyer, David Denardo, Raphael Kopan and Wayne Wasserman. Zurich, Switzerland; Vancouver, Canada and Los Angeles, CA. 007 Phenotypic analysis of dendritic cells infiltrating a spontaneous model 719 InfluenceYokoyama. ofSt. adipose-derived Louis, MO and Cincinnati, extra-cellular OH. fraction on skin repair 735 Phosphorylation of SMAD2 linker site Thr220 is a marker for quiescent of basal cell carcinoma. Christopher Nirschl, Yong Liu, Pinru Wu, Karyn 022 BarbaraTopical applicationBellei, Emilia ofMigliano, eupatilin Marinella ameliorates Tedesco, atopic Stefania dermatitis-like Bucher and skin stem cells. Claudia D Andl, Thomas Andl. Nashville, TN. Haitz and Niroshana Anandasabapathy. Boston, MA. Maurolesions Picardo. of NC/Nga Rome, mice. Italy. Young Min Park, Ji Hyun Lee, Ye Jin Lee and Jun 736* Estrogen receptor alpha-mediated control of growth factor production 008 Potential mechanisms for loss of hair follicle immune privilege in 720 Ayoung novel Lee. animal Seoul, model Korea for (the lichen Republic planus. of). Etienne Wang, Sivan Harel, from nipple fibroblasts. Hsin-Jung Wu, Dan F Spandau, Sunil S. Tholpady + patients with alopecia areata following hepatitis B vaccination. 023 VictorCD8αα Luria T cells and contribute Angela Christiano. to lichen planusNew York independence City, NY and ofBoston, LAMP1- MA. and John G. Foley. Bloomington, IN and Indianapolis, IN. Christopher Richardson, Elaine Gilmore and Brian Poligone. Rochester, NY. 721* Inhibitionmeditated degranulation.of Apoptosis signal-regulating Bing Li, Xiuwen Sun kinase and 1Gang alters Wang. differentiation Xi’an, 009* CCL17 attenuates tumor immunity by increasing regulatory T cells and ofChina. the wound epithelium to enhance tissue regeneration. Theresa Th2 cells while decreasing myeloid-derived suppressor cells in tumor 024 AImmunomodulatory Freeman, Natalie Chernets, effects Deepaof nanoparticles Kurpad and on My the G Mahoney.contact microenvironment. Makoto Sugaya, Sohshi Morimura, Tomonori Oka, Philadelphia,hypersensitivity PA. response in C57BL/6 hairless mice. Samreen Jatana, Brian C Palmer and Lisa A DeLouise. Rochester, NY. Hiraku Suga, Tomomitsu Miyagaki, Yuichiro Tsunemi, Yoshihide Asano, 722 Dielectric barrier discharge plasma treatment increases tissue 025 Capturing functional conservation between human skin and mouse DC Yayoi Tada, Takafumi Kadono and Shinichi Sato. Tokyo, Japan. oxygenation during murine ear regeneration. Natalie Chernets, John R systems for generating better vaccines. Eynav Klechevsky. Saint Louis, 010 Distinctive downmodulation of plasmacytoid dendritic cell by vitamin Eisenbrey, Ji-Bin Liu, Deepa Kurpad, Flemming Forsberg and Theresa A MO. D3 analogue in its interferon-α production and chemotactic activity. Freeman. Philadelphia, PA. 026* Human skin is protected by four functionally and phenotypically Takahiro Suzuki, Yoshiki Tokura. Hamamatsu, Japan. 723* Ephrin-A ligand loss enhances keratinocyte migration via ligand- discrete populations of resident and recirculating memory T cells. Rei 011** A wave of regulatory T cells into neonatal skin mediates tolerance to independent EphA2 action. Spiro Getsios, Nihal Kaplan, Bethany Elena Watanabe, Ahmed Gehad, Chao Yang, Laura Campbell, Jessica Emberley commensal microbes . Tiffany C Scharschmidt, Kimberly S Vasquez, Hong- Perez White, Ji Zheng, Paul Hoover, Rosa Ventrella, William R Swindell, Teague, Victor Huang, Tiago R Matos, Thomas S. Kupper and Rachael An Truong, Sofia V. Gearty, Mariela L Pauli, Audrey Nosbaum, Michael Johann Eli Gudjonsson and Bingcheng Wang. Chicago, IL; Cleveland, OH Clark. Boston, MA. Otto, James J Moon, Abul K. Abbas, Michael A Fischbach and Michael and Ann Arbor, MI. 027 Novel STAT3 inhibitor LLL12 significantly reduces IL-17, IL-22, and IFN- David Rosenblum. San Francisco, CA; Bethesda, MD and Charlestown, 724 Topical application of mesenchymal stem cells accelerates healing of gamma mRNA expression in psoriatic PBMCs. Justin G Hastings, Xiaoli MA. wounds in a scleroderma mouse model. Tatyana Yufit, Xiaofeng Lin, Zhang, Jiayuh Lin, Chenglong Li and Henry K Wong. Columbus, OH. 012 Keratin 17 enhances the chemotaxis of neutrophils through regulating David Fiore, Polly Carson, Marta Otero-Vinas and Vincent Falanga. Boston, 028* GILT-mediated processing of a self and melanoma antigen in thymic chemokine CXCL1 secretion in keratinocytes via PI3k/AKT/NF-κB MA and Vic, Spain. epithelial cells promotes deletion and regulatory T cells. Karen Taraszka pathway. Er-Le Dang, Liang Jin, Chang-xu Han, Bing Li, Man Jiang and 725 A novel assay for evaluating wound healing in a full-thickness in vitro Hastings, Matthew Rausch, Todd C. Metzger, Michael Waterfield, Jessica Gang Wang. Xi’an, China. human skin model. Michael Allen Bachelor, Alexander Armento, Jonathan Cortez and Mark S. Anderson. Phoenix, AZ and San Francisco, CA. 013* Contributions of skin resident and recirculating memory T cells to Oldach, Mitchell Klausner and Patrick J. Hayden. Ashland, MA. depigmentation in vitiligo. Jillian Richmond, Mehdi Rashighi, Priti 726 Acute immune effects and tissue destruction in mice following skin Agarwal and John E Harris. Worcester, MA. exposure to sulfur mustard. Lopa Das, Kurt Quoc Lu. Cleveland, OH.

Notes: Notes:

1 99 26 AUTHOR INDEX AUTHOR INDEX

Arcioni, Marianne 356 Arcioni, Marianne 356 A A Aasi, Sumaira Z. 209 Ardeleanu, Marius 169 Aasi, Sumaira Z. 209 Ardeleanu, Marius 169 Abaci, Hasan E. 401, 427, 715 Arenas, Elsa 224, 230 Abaci, Hasan E. 401, 427, 715 Arenas, Elsa 224, 230 Abbas, Abul K. 011, 016, 029, 034, 675 Ariizumi, Kiyoshi 096, 199 Abbas, Abul K. 011, 016, 029, 034, 675 Ariizumi, Kiyoshi 096, 199 Abbas, Tazeen 229 Armento, Alexander 566, 725 Abbas, Tazeen 229 Armento, Alexander 566, 725 Abdel-Malek, Zalfa A. 607 Armile, James A. 212 Abdel-Malek, Zalfa A. 607 Armile, James A. 212 Abdelgawwad, Mohammad 582 Armstrong, April W. 246, 303 Abdelgawwad, Mohammad 582 Armstrong, April W. 246, 303 Abdul-Wahab, Alya 411 Armstrong, Cheryl A. 520 Abdul-Wahab, Alya 411 Armstrong, Cheryl A. 520 Abe, Riichiro 361 Arnold, Steven E. 310 Abe, Riichiro 361 Arnold, Steven E. 310 Abecasis, Goncalo 438, 440 Arozenius, Helena 006 Abecasis, Goncalo 438, 440 Arozenius, Helena 006 Abels, Christoph 359 Arron, Sarah 102, 133, 384 Abels, Christoph 359 Arron, Sarah 102, 133, 384 Abeni, Damiano 417 Artis, Keli 193, 350 Abeni, Damiano 417 Artis, Keli 193, 350 Achtman, Jordan C. 073 Artomov, Mykyta 134 Achtman, Jordan C. 073 Artomov, Mykyta 134 Adachi, Akimasa 220 Asada, Hideo 054 Adachi, Akimasa 220 Asada, Hideo 054 Adams, Peter D. 156 Asano, Yoshihide 009, 177 Adams, Peter D. 156 Asano, Yoshihide 009, 177 Adase, Chris 337 Asgari, Maryam M. 305 Adase, Chris 337 Asgari, Maryam M. 305 Adhami, Vaqar 559 Ashbaugh, Alyssa 509, 510 Adhami, Vaqar 559 Ashbaugh, Alyssa 509, 510 Adhikary, Gautam 143, 389 Aspiroz, Carmen 189 Adhikary, Gautam 143, 389 Aspiroz, Carmen 189 Adler, Brandon 239, 295, 531, 713 Astry, Brian 557 Adler, Brandon 239, 295, 531, 713 Astry, Brian 557 Admani, Shehla 219 Ata, Mohammad O. 581 Admani, Shehla 219 Ata, Mohammad O. 581 Adotama, Prince 329 Atanasova, Velina 426 Adotama, Prince 329 Atanasova, Velina 426 Afanasiev, Olga 015 Athar, Mohammad 150, 571, 651 Afanasiev, Olga 015 Athar, Mohammad 150, 571, 651 Afaq, Farrukh 571, 638 Atsugi, Toru 352 Afaq, Farrukh 571, 638 Atsugi, Toru 352 Afshar, Maryam 207 Atwood, Scott 120, 132, 174 Afshar, Maryam 207 Atwood, Scott 120, 132, 174 Agak, George W. 407, 531 Atzmony, Lihi 457 Agak, George W. 407, 531 Atzmony, Lihi 457 Agarwal, Ashwin 164, 251 Aust, Samantha 083, 084 Agarwal, Ashwin 164, 251 Aust, Samantha 083, 084 Agarwal, Priti 013 Awgulewitsch, Alexander 690 Agarwal, Priti 013 Awgulewitsch, Alexander 690 Aggarwal, Rohit 050 Ayehunie, Seyoum 566 Aggarwal, Rohit 050 Ayehunie, Seyoum 566 Agón, Pedro 275 Ayithan, Natarajan 544 Agón, Pedro 275 Ayithan, Natarajan 544 Ahmad, Israr 581 Azambuja, Ana P. 316, 317, 318 Ahmad, Israr 581 Azambuja, Ana P. 316, 317, 318 Ahmad, Nihal 654 Aziz, Ahmar 709 Ahmad, Nihal 654 Aziz, Ahmar 709 Ahmed, Rehana L. 612 Ahmed, Rehana L. 612 Ahn, Jaewoo 198 Ahn, Jaewoo 198 Ahn, Richard 443 Ahn, Richard 443 B B Ahn, Sung K. 660 Babineau, Denise 350 Ahn, Sung K. 660 Babineau, Denise 350 Ahrns, Hadjh S. 298 Bacchiocchi, Antonella 148, 606, 635 Ahrns, Hadjh S. 298 Bacchiocchi, Antonella 148, 606, 635 Aiba, Setsuya 700 Bachelor, Michael A. 566, 647, 725 Aiba, Setsuya 700 Bachelor, Michael A. 566, 647, 725 Akhtar, Nosheen 598 Bae, Jong H. 660 Akhtar, Nosheen 598 Bae, Jong H. 660 Al-Sadek, Camli 582 Baek, Yoosang 198 Al-Sadek, Camli 582 Baek, Yoosang 198 Alberico, Stephanie 084 Baer, Janina 679 Alberico, Stephanie 084 Baer, Janina 679 Albuquerque, Celina 065 Baerenwald, Devin 138 Albuquerque, Celina 065 Baerenwald, Devin 138 Alessi Cesar, Sabrina 250 Bagby, Stacey 624 Alessi Cesar, Sabrina 250 Bagby, Stacey 624 Alexeev, Vitali 652 Baghdadi, T 692 Alexeev, Vitali 652 Baghdadi, T 692 Algazi, Alain 194 Bai, Jing 088 Algazi, Alain 194 Bai, Jing 088 Ali, Niwa 675 Baida, Gleb 491 Ali, Niwa 675 Baida, Gleb 491 Alijarde, Roberto 275 Bailey, Irene 174 Alijarde, Roberto 275 Bailey, Irene 174 Alkelai, A 066 Bak, Soon-Sun 659 Alkelai, A 066 Bak, Soon-Sun 659 Ally, Mina S. 132, 174, 315 Bakshi, Pooja 396 Ally, Mina S. 132, 174, 315 Bakshi, Pooja 396 Almeida, Adam R. 648 Ballard, David H. 536 Almeida, Adam R. 648 Ballard, David H. 536 Alshehri, Wedad 173 Balooch, Guive 249 Alshehri, Wedad 173 Balooch, Guive 249 Alves, Paul 056 Banez, Lionel 251 Alves, Paul 056 Banez, Lionel 251 Alvim, Rafael 316, 317, 318 Banga, Ajay K. 063, 338, 362, 396 Alvim, Rafael 316, 317, 318 Banga, Ajay K. 063, 338, 362, 396 Amagai, Masayuki 098, 352, 508 Bao, Xiaomin 451 Amagai, Masayuki 098, 352, 508 Bao, Xiaomin 451 Ambrose, Jeffery J. 536 Bar-Hen, Avner 269 Ambrose, Jeffery J. 536 Bar-Hen, Avner 269 Amin, Ahmad S. 260 Baratti, Mariana 525 Amin, Ahmad S. 260 Baratti, Mariana 525 Amoh, Yasuyuki 691 Barcellos-Hoff, Mary Helen 580 Amoh, Yasuyuki 691 Barcellos-Hoff, Mary Helen 580 Anandasabapathy, Niroshana 003, 004, 007 Bardot, Evan 680 Anandasabapathy, Niroshana 003, 004, 007 Bardot, Evan 680 Anderson, Abraham 281 Barkoukis, Hope 214 Anderson, Abraham 281 Barkoukis, Hope 214 Anderson, Mark S. 028 Barnes, Drew H. 552 Anderson, Mark S. 028 Barnes, Drew H. 552 Anderson, Mary E. 511 Barnes, Kathleen 350 Anderson, Mary E. 511 Barnes, Kathleen 350 Andl, Claudia D. 711, 735 Baron, Elma D. 584 Andl, Claudia D. 711, 735 Baron, Elma D. 584 Andl, Thomas 711, 735 Barthel, Steven R. 004 Andl, Thomas 711, 735 Barthel, Steven R. 004 Andre-Frei, Valerie 380, 485, 542 Barzegar, Mohammad R. 464, 466 Andre-Frei, Valerie 380, 485, 542 Barzegar, Mohammad R. 464, 466 Andrews, J. 259, 395, 705, 730, 733 Barzilai, A 066 Andrews, J. 259, 395, 705, 730, 733 Barzilai, A 066 Angra, Divya 112 Basel-Vanagaite, Lina 457 Angra, Divya 112 Basel-Vanagaite, Lina 457 Ansell, David 666 Bashir, Hasan 149 Ansell, David 666 Bashir, Hasan 149 Antaya, Richard 436 Bashir, Muhammad 056, 067 Antaya, Richard 436 Bashir, Muhammad 056, 067 Antes, Travis 130 Bashkirova, Elizaveta 428 Antes, Travis 130 Bashkirova, Elizaveta 428 Aplin, Andrew 107 Basiri, M R. 464 Aplin, Andrew 107 Basiri, M R. 464 Arave, Rowan 625 Bastien, Philippe 249 Arave, Rowan 625 Bastien, Philippe 249 Arbieva, Zarema 567 Batazzi, Adriana 144 Arbieva, Zarema 567 Batazzi, Adriana 144 Arbiser, Jack L. 063, 176, 495 Baudouin, Caroline 197, 369 Arbiser, Jack L. 063, 176, 495 Baudouin, Caroline 197, 369 Arcaroli, John J. 624 Bauer, Jürgen 136 Arcaroli, John J. 624 Bauer, Jürgen 136 Archer, Nate 510 Baum, S 066 Archer, Nate 510 Baum, S 066 S128 Journal of Investigative Dermatology (2015), Volume 135 S128 Journal of Investigative Dermatology (2015), Volume 135 100 AUTHOR INDEX AUTHOR INDEX

Arcioni, Marianne 356 Bauza,A Eric 356, 358 Bosenberg, Marcus 632, 634 Aasi, Sumaira Z. 209 Ardeleanu, Marius 169 Beachy, Phillip 174 Boss, Cristina 420 Arenas, Elsa 224, 230 Bec,Abaci, Julien Hasan E. 170401, 427, 715 Botchkarev, Vladimir A. 679, 709 Bechara,Abbas, Abul Etelvino K. 606,011, 635 016, 029, 034, 675 Botten,Ariizumi, Giovanni Kiyoshi 574096, 199 Beck,Abbas, Kristen Tazeen M. 620,229 628 Botto,Armento, Jean MarieAlexander 355,566, 356, 725 357, 358 Beck,Abdel-Malek, Lisa A. Zalfa A. 213,607 346, 350 Boudhar,Armile, SanaaJames A. 533212 Beckers,Abdelgawwad, Johannes Mohammad 646582 Bouslimani,Armstrong, Amina April W. 193246, 303 Bedard,Abdul-Wahab, Mary Alya 005,411 505 Bouwstra,Armstrong, Joke Cheryl A. 342,520 343 Beis,Abe, Erato Riichiro 271361 Bowcock,Arnold, StevenAnne M. E. 443310 Belknap,Abecasis, Steven Goncalo M. 260438, 440 Bowszyc-Dmochowska,Arozenius, Helena Monika 285006 Bellei,Abels, Barbara Christoph 719359 Box,Arron, Neil Sarah 366102, 133, 384 Bemmels,Abeni, Damiano Heather 277417 Boxer,Artis, Lisa Keli D. 391193, 350 Ben-Amitay,Achtman, Jordan Dan C. 457073 Boyden,Artomov, Lynn Mykyta 444134 Ben-Ary,Adachi, GuyAkimasa 707220 Boyers,Asada, Lindsay Hideo N. 300,054 313 Ben-Asher,Adams, Peter E D. 066156 Bradley,Asano, Bridget Yoshihide 046,009, 061 177 Benlhabib,Adase, Chris Elhabib 247337 Bradley,Asgari, Robert Maryam M. 387305 Berger,Adhami, Shelley Vaqar L. 156559 Brand,Ashbaugh, Rhonda Alyssa M. 402509, 510 Bergeron,Adhikary, Laurine Gautam 355,143, 357, 389 358 Brar,Aspiroz, Kanwaljit Carmen 344189 Bergfeld,Adler, Brandon Wilma F. 665239, 295, 531, 713 Brash,Astry, Douglas Brian E. 606,557 635 Bergstrom,Admani, Shehla David E. 442,219 455 Braumüller,Ata, Mohammad Heidi O. 136,581 140, 420 Berke,Adotama, Zsofia Prince 221329 Bredif,Atanasova, Stephanie Velina 369,426 718 Berkers,Afanasiev, Tineke Olga 342015 Breen,Athar, Catherine Mohammad 498150, 571, 651 Berking,Afaq, Farrukh Carola 646571, 638 Brenner,Atsugi, EllenToru 136,352 140, 420 Beroukhim,Afshar, Maryam Kourosh 095207 Breslow,Atwood, Jan Scott 190120, 132, 174 Berroth,Agak, George Andreas W. 469407, 531 Breton,Atzmony, Lionel Lihi 269457 Berry,Agarwal, Adam Ashwin 036,164, 165 251 Breyfogle,Aust, Samantha Bridget 647083, 084 Besch,Agarwal, Robert Priti 646013 Brezinski,Awgulewitsch, Elizabeth Alexander A. 303690 Besen,Aggarwal, Justin Rohit 232050 Bridges,Ayehunie, Alina Seyoum G. 557566 Best,Agón, Arthur Pedro 270275 Briley,Ayithan, Will Natarajan 373544 Betancourt,Ahmad, Israr Aline 655581 Brodmerkel,Azambuja, Carrie Ana P. 445316, 317, 318 Bhaduri,Ahmad, AparnaNihal 341654 Brohem,Aziz, Ahmar Carla A. 363709 Bhalla,Ahmed, Pankaj Rehana L. 491612 Brooks, Lionel 133 Bhandarkar,Ahn, Jaewoo Sulochana 176198 Brooks, Yang S. 121 Bhatia,Ahn, Richard Ayesha 500,443 729 Broussard,B Joshua A. 475 Bhatia,Ahn, Sung Jasvinder K. 205660 Brownell,Babineau, Isaac Denise 241350 Bhattacharya,Ahrns, Hadjh Tanya S. 260298 Brozowski,Bacchiocchi, Jaime Antonella 152148, 606, 635 Bhoj,Aiba, Vijay Setsuya G. 059700 Brueggemann,Bachelor, Michael Andrea A. 667566, 647, 725 Bian,Akhtar, Li Nosheen 448598 Bruhs,Bae, AnikaJong H. 518660 Bible,Al-Sadek, Paul Camli 097582 Bruins,Baek, Finola Yoosang 260198 Bickers,Alberico, David Stephanie R. 115,084 150 Brunner,Baer, Janina Georg 484679 Bigler,Albuquerque, Jeannette Celina 281065 Brusq,Baerenwald, Jean-Marie Devin 505138 Bikle,Alessi Dan Cesar, Sabrina 699250 Bucher,Bagby, Stefania Stacey 719624 Bilguvar,Alexeev, Kaya Vitali 465652 Buck,Baghdadi, Jochen T 146692 Birlea,Algazi, Stanca Alain A. 641194 Budanov,Bai, Jing Andrey 107088 Biro,Ali, NiwaTamas 666675 Budunova,Baida, Gleb Irina 491491 Bishard,Alijarde, Kristina Roberto 586275 Bui,Bailey, Thi Irene 506,174 527 Bissonnette,Alkelai, A Robert 445066 Bukhtiyarov,Bak, Soon-Sun Yuri E. 367659 Bivik,Ally, CeciliaMina S. 546132, 174, 315 Bulock,Bakshi, Karen Pooja 487,396 642 Blacker,Almeida, Alyssa Adam R. 407648 Bunick,Ballard, Christopher David H. G. 349,536 353 Blazar,Alshehri, Bruce Wedad 408173 Bürgler,Balooch, Christina Guive 125249 Blecher,Alves, Paul Karin 531056 Burlingame,Banez, Lionel Al 613251 Bloch,Alvim, Wilhelm Rafael 375316, 317, 318 Burns,Banga, Erin Ajay M. K. 582063, 338, 362, 396 Blom,Amagai, Astrid Masayuki 256098, 352, 508 Bushman,Bao, Xiaomin Frederic D. 553451 Blumbach,Ambrose, JefferyKatrin J. 484536 Busuttil,Bar-Hen, Valère Avner 355,269 357, 358 Blumenberg,Amin, Ahmad Miroslav S. 097,260 389 Byrne,Baratti, Michael Mariana 642525 Bobr,Amoh, Aleh Yasuyuki 557691 Barcellos-Hoff, Mary Helen 580 Bochkov,Anandasabapathy, Valery Niroshana 594003, 004, 007 Bardot, Evan 680 Bochner,Anderson, R Abraham 378,281 450 CBarkoukis, Hope 214 Bock,Anderson, Suzanne Mark S. 351028 Cabrales,Barnes, PedroDrew H. 713552 Boedigheimer,Anderson, Mary Michael E. 281511 Cadau,Barnes, Sebastien Kathleen 542350 Boelens,Andl, Claudia Jaap J. D. 411711, 735 Cadwell,Baron, ElmaChantel D. 704584 Boguniewicz,Andl, Thomas Mark 350711, 735 Calderone,Barthel, Steven Ken R. 254004 Boher,Andre-Frei, Aurelie Valerie 485380, 485, 542 Camhi,Barzegar, Maya Mohammad R. 033,464, 561 466 Boland,Andrews, Kelsey J. 118259, 395, 705, 730, 733 Campbell,Barzilai, KevinA T. 586066 Boldrini,Angra, Divya Nathaly 363112 Campbell,Basel-Vanagaite, Laura Lina 026,457 225 Bollag,Ansell, Wendy David B. 403666 Campiche,Bashir, Hasan Remo 364149 Bonifacio,Antaya, Richard Kathleen M. 266,436 445 Cantley,Bashir, Lewis Muhammad C. 146,056, 626 067 Bonnel,Antes, TravisDavid 376130 Cao,Bashkirova, Wenluo Elizaveta 691428 Bonner,Aplin, AndrewMichael 176,107 495 Cao,Basiri, Xu M R. 456464 Bonventre,Arave, Rowan Josephine 531625 Cao,Bastien, Yu-An Philippe 469249 Booker,Arbieva, Reid Zarema C. 108567 Capallere,Batazzi, AdrianaChristophe 355,144 356, 357, 358 Booker,Arbiser, Sarah Jack L. 061063, 176, 495 Capell,Baudouin, Brian CarolineC. 156197, 369 Bordeaux,Arcaroli, JohnJeremy J. 334624 Capozza,Bauer, Jürgen Korey L. 159136 Bordelon,Archer, Nate Jenna 639510 Cardenas,Baum, S Karissa 586066

S128 Journal of Investigative Dermatology (2015), Volume 135 www.jidonline.org S129 101 AUTHOR INDEX AUTHOR INDEX

Arcioni, Marianne 356 Cardia, James 487, 642 Cho, Soyun 217, 481 A Aasi, Sumaira Z. 209 Ardeleanu, Marius 169 Cardon, Zachary E. 186 Choate, Keith A. 200, 436, 444, 458, 465 Abaci, Hasan E. 401, 427, 715 Arenas, Elsa 224, 230 Cardones, Adela 164, 240, 251 Choi, Eun J. 071 Abbas, Abul K. 011, 016, 029, 034, 675 Ariizumi, Kiyoshi 096, 199 Carey, Cara 035, 414 Choi, Jaehyuk 222 Abbas, Tazeen 229 Armento, Alexander 566, 725 Carlson, Kacie 222 Choi, Mira 217, 481 Abdel-Malek, Zalfa A. 607 Armile, James A. 212 Carson, Polly 631, 724, 728, 731 Choi, Soon Yong 540 Abdelgawwad, Mohammad 582 Armstrong, April W. 246, 303 Carter, Joi B. 191 Choi, Yeun Ja 687 Abdul-Wahab, Alya 411 Armstrong, Cheryl A. 520 Carty, Nancy 212 Chong, Benjamin F. 186 Abe, Riichiro 361 Arnold, Steven E. 310 Carucci, John A. 698 Chong, Heng 538 Abecasis, Goncalo 438, 440 Arozenius, Helena 006 Carvalho, Hernandes 525 Choudhary, Vivek 403 Abels, Christoph 359 Arron, Sarah 102, 133, 384 Cassell, Martin 084 Chrétien, Aline 335 Abeni, Damiano 417 Artis, Keli 193, 350 Castanedo-Cázares, Juan P. 615 Christiano, Angela 019, 079, 089, 090, 238, 264, 272, 401, Achtman, Jordan C. 073 Artomov, Mykyta 134 Cataisson, Christophe 097, 137, 153 419, 427, 448, 459, 461, 682, 683, 715, Adachi, Akimasa 220 Asada, Hideo 054 Celli, Anna 381 720 Adams, Peter D. 156 Asano, Yoshihide 009, 177 Cenizo, Valérie 542 Chu, Chia-Yu 109, 633 Adase, Chris 337 Asgari, Maryam M. 305 Cerise, Jane E. 079, 264, 459, 682 Chu, Emily 240 Adhami, Vaqar 559 Ashbaugh, Alyssa 509, 510 Cesar, Carlos L. 525, 563 Chu, Howard 252, 556 Adhikary, Gautam 143, 389 Aspiroz, Carmen 189 Chadoutaud, Bernard 197 Chu, Mon Li 502 Adler, Brandon 239, 295, 531, 713 Astry, Brian 557 Chambon, P 155 Chun, Kimberly 193, 282 Admani, Shehla 219 Ata, Mohammad O. 581 Chamcheu, Jean Christopher 559 Chung, Byung-Min 144 Adotama, Prince 329 Atanasova, Velina 426 Champer, Jackson 407 Chung, Hye Jin 259, 395 Afanasiev, Olga 015 Athar, Mohammad 150, 571, 651 Chan, Chih-Chieh 670 Chung, Jin-Ho 217, 481, 482, 483, 601 Afaq, Farrukh 571, 638 Atsugi, Toru 352 Chandra, Jyotsna 215 Chung, Jin-Sung 096, 199 Afshar, Maryam 207 Atwood, Scott 120, 132, 174 Chang, Anne Lynn S. 120, 130, 132, 135, 174, 234, 244, 265 Chung, Jina 310 Agak, George W. 407, 531 Atzmony, Lihi 457 Chang, Howard 265, 451 Chung, Keeyang 131 Agarwal, Ashwin 164, 251 Aust, Samantha 083, 084 Chang, Kee-Lung 103 Chuong, Cheng-Ming 717 Agarwal, Priti 013 Awgulewitsch, Alexander 690 Chang, Michelle 581 Churton, Sarah 214 Aggarwal, Rohit 050 Ayehunie, Seyoum 566 Chang, Oliver 256 Cˇ iháková, Daniela 144 Agón, Pedro 275 Ayithan, Natarajan 544 Charbonnier, Soeli 405 Cintra, Maria 525 Ahmad, Israr 581 Azambuja, Ana P. 316, 317, 318 Charruyer, Alexandra 384 Claremon, David 367 Ahmad, Nihal 654 Aziz, Ahmar 709 Chaudhry, Usman 169 Clark, Caitlin 246 Ahmed, Rehana L. 612 Chavan, Manasi 336, 380 Clark, Charlotte 238, 272 Ahn, Jaewoo 198 Chaves-Rodriquez, Maria Ines 559 Clark, Lee N. 406 Ahn, Richard 443 Chen, Guo 625 Clark, Rachael 026, 039, 041, 072, 082, 147, 225, 415, B Ahn, Sung K. 660 Babineau, Denise 350 Chen, Gwo-Shing 103, 701 421 Ahrns, Hadjh S. 298 Bacchiocchi, Antonella 148, 606, 635 Chen, Haoyan 443 Clark, Richard A. 141, 261, 649, 687, 710 Aiba, Setsuya 700 Bachelor, Michael A. 566, 647, 725 Chen, Huan-Yuan 528 Clendaniel, Alicea 531 Akhtar, Nosheen 598 Bae, Jong H. 660 Chen, Hung-Lin 528 Clowry, Julianne 210 Al-Sadek, Camli 582 Baek, Yoosang 198 Chen, James 459, 683 Clynes, Raphael 019, 079, 089, 090, 238, 264, 272, 448, Alberico, Stephanie 084 Baer, Janina 679 Chen, James C. 682 682 Albuquerque, Celina 065 Baerenwald, Devin 138 Chen, Jiang 141, 649, 687 Coarfa, C 110 Alessi Cesar, Sabrina 250 Bagby, Stacey 624 Chen, Jie 698 Coates, Sarah J. 226 Alexeev, Vitali 652 Baghdadi, T 692 Chen, Jing 060 Coffman, Abigail 401, 427 Algazi, Alain 194 Bai, Jing 088 Chen, Julia 244 Cogan, Jon 490, 712 Ali, Niwa 675 Baida, Gleb 491 Chen, Mei 408, 490, 500, 712, 729 Coghill, Robert 187 Alijarde, Roberto 275 Bailey, Irene 174 Chen, Nannan 603 Cohen, Benjamin 326 Alkelai, A 066 Bak, Soon-Sun 659 Chen, Pin-Chun 109 Cohen, Brandon 211 Ally, Mina S. 132, 174, 315 Bakshi, Pooja 396 Chen, Siming 663 Cohn, Heather Irina 424 Almeida, Adam R. 648 Ballard, David H. 536 Chen, Stella 282 Colburn, Zachary 703 Alshehri, Wedad 173 Balooch, Guive 249 Chen, Suephy C. 236, 284, 291, 307 Colevas, Dimitrios 174 Alves, Paul 056 Banez, Lionel 251 Chen, Yifang 430 Collier, Annie E. 398 Alvim, Rafael 316, 317, 318 Banga, Ajay K. 063, 338, 362, 396 Chen, Ying 697 Collins, Paul 210 Amagai, Masayuki 098, 352, 508 Bao, Xiaomin 451 Chen, Yiyin E. 616 Compans, Richard W. 045 Ambrose, Jeffery J. 536 Bar-Hen, Avner 269 Chen, Yu-Ju 671 Compton, Leigh A. 227 Amin, Ahmad S. 260 Baratti, Mariana 525 Chen, Zhengyi 334 Conniff, Tara 269 Amoh, Yasuyuki 691 Barcellos-Hoff, Mary Helen 580 Chen, Zhiguo 108 Contag, Christopher 469 Anandasabapathy, Niroshana 003, 004, 007 Bardot, Evan 680 Cheng, Nancy 160, 231 Conway, Daniel 704 Anderson, Abraham 281 Barkoukis, Hope 214 Chernets, Natalie 721, 722 Cook, Jonathan 040 Anderson, Mark S. 028 Barnes, Drew H. 552 Cheung, Carolyn 348, 360 Cook, Steven 005 Anderson, Mary E. 511 Barnes, Kathleen 350 Chien, Andy 305 Cooper, Kevin D. 214, 245, 278, 292, 332, 501 Andl, Claudia D. 711, 735 Baron, Elma D. 584 Chien, Anna L. 160, 231, 250, 312, 314, 599 Cooper, Matthew 038 Andl, Thomas 711, 735 Barthel, Steven R. 004 Chiesa, Zelma C. 302 Coquery, Christine 506, 527 Andre-Frei, Valerie 380, 485, 542 Barzegar, Mohammad R. 464, 466 Chinnaiyan, Arul M. 440 Corrêa da Rosa, Joel M. 190, 198, 255, 392, 562 Andrews, J. 259, 395, 705, 730, 733 Barzilai, A 066 Chiou, Albert S. 209 Cortés-García, Diego 615 Angra, Divya 112 Basel-Vanagaite, Lina 457 Chitsazzadeh, Vida 110 Cortez, Jessica 028 Ansell, David 666 Bashir, Hasan 149 Chittur, Sridar V. 706 Corwin, Jessica 195 Antaya, Richard 436 Bashir, Muhammad 056, 067 Chiu, Hsien-Yi 670 Costa, Diego L. 065 Antes, Travis 130 Bashkirova, Elizaveta 428 Cho, Alice 046 Costa, Marco Antonio T. 363 Aplin, Andrew 107 Basiri, M R. 464 Cho, Eunyoung 178, 299, 304, 311, 323, 325 Costa, Max 602 Arave, Rowan 625 Bastien, Philippe 249 Cho, Gunsik 274 Cote-Sierra, Javier 005, 505, 506, 527 Arbieva, Zarema 567 Batazzi, Adriana 144 Cho, Hyunje G. 410 Coulombe, Pierre 144 Arbiser, Jack L. 063, 176, 495 Baudouin, Caroline 197, 369 Cho, Joseph 625 Coulon, Rick 063 Arcaroli, John J. 624 Bauer, Jürgen 136 Cho, Michael Jeffrey T. 018, 059 Courderot-Mazuyer, Carol 718 Archer, Nate 510 Baum, S 066 Cho, Nam H. 249 Coussens, Lisa M. 127 S128 Journal of Investigative Dermatology (2015), Volume 135 S130 Journal of Investigative Dermatology (2015), Volume 135 102 AUTHOR INDEX AUTHOR INDEX

Arcioni, Marianne 356 Couts,A Kasey L. 106 Dennis, Phillip A. 137 Ardeleanu, Marius 169 Cowen,Aasi, Sumaira Edward Z. W. 168209 Dentchev, T 157, 416 Cowin,Abaci, HasanAllison E. 538401, 427, 715 DePianto,Arenas, ElsaDaryle 144224, 230 Craiglow,Abbas, Abul Brittany K. 444,011, 458 016, 029, 034, 675 Desai,Ariizumi, Amishi Kiyoshi 158096, 199 Criswell,Abbas, Tazeen Lindsey A. 443229 Desai,Armento, Nisha Alexander 672566, 725 Crosby,Abdel-Malek, Heidi Zalfa A. 545607 Desai,Armile, Tejal James A. 351212 Crowe,Abdelgawwad, James Mohammad 018582 Deshayes,Armstrong, Stephanie April W. 407246, 303 Crowson,Abdul-Wahab, Cynthia Alya S. 050411 DeStefano,Armstrong, Gina Cheryl M. A. 448,520 683 Crumrine,Abe, Riichiro Debra 348,361 389 Detmar,Arnold, Michael Steven E. 734310 Cruz,Abecasis, Ponciano Goncalo D. 096,438, 199 440 Devalaraja,Arozenius, Matt Helena 221006 Cucumel,Abels, Christoph Karine 354,359 627 Devlin,Arron, Phillip Sarah 415102, 133, 384 Cuddapah,Abeni, Damiano Chennakesava 476417 Dey-Rao,Artis, Keli Rama 057,193, 069, 350 429 Cui,Achtman, Jiawei Jordan C. 685073 DiArtomov, Nardo, Anna Mykyta 560,134 608 Cui,Adachi, Yali Akimasa 629220 Diaconu,Asada, Hideo Doina 033,054 561 Cunningham,Adams, Peter TrevorD. J. 021156 Diamond,Asano, Yoshihide Ariana C. 638009, 177 Cyster,Adase, JasonChris 555337 Diaz,Asgari, Ana Maryam M. 146305 Czarnowicki,Adhami, Vaqar Tali 036,559 055, 165, 255 Diaz,Ashbaugh, Luis A. Alyssa 091,509, 092, 510 152, 382, 494 Adhikary, Gautam 143, 389 Didona,Aspiroz, Biagio Carmen 417189 Adler, Brandon 239, 295, 531, 713 Didona,Astry, BrianDario 417557 DAdmani, Shehla 219 Dieterich,Ata, Mohammad Lothar O. 734581 daAdotama, Silva, Vanessa Prince V. 363329 DiGiovanna,Atanasova, JohnVelina J. 112,426 195 Dadras,Afanasiev, Soheil Olga S. 204,015 442, 453, 661 Dinarello,Athar, Mohammad Charles A. 640150, 571, 651 Dagnino,Afaq, Farrukh Lina 496571, 638 Ding,Atsugi, Anan Toru 288352 Dai,Afshar, Peihong Maryam 570207 Ding,Atwood, Catherine Scott 344120, 132, 174 Dai,Agak, Wei George W. 456407, 531 Ding,Atzmony, Julia Lihi 167457 Dai,Agarwal, Xiuju Ashwin 472164, 251 Ding,Aust, Jun Samantha 440083, 084 Dai,Agarwal, Zhenpeng Priti 019,013 089, 090, 448, 682 Ding,Awgulewitsch, Wanhong Alexander 020,690 532 Daily,Aggarwal, Kenneth Rohit 241050 Dionne,Ayehunie, L A. Seyoum 468566 Dakin,Agón, PedroAdam 548275 Dionne,Ayithan, Louise Natarajan 453,544 455 Daly,Ahmad, Mark Israr 134581 DiPersio,Azambuja, C. M. Ana P. 706316, 317, 318 Dam,Ahmad, Duncan Nihal Hieu M. 480654 DiPersio,Aziz, Ahmar John F. 038709 Dana,Ahmed, Ali Rehana L. 294612 Dissanayake, Shashini 707 Danesh,Ahn, Jaewoo Melissa 095198 Divito, Sherrie J. 043, 227, 262 Dang,Ahn, RichardEr-Le 012,443 587 Dlugosz,B Andrzej 111, 124, 155 Daniel,Ahn, Sung Weston K. 413660 Dmochowski,Babineau, Denise Marian 285350 Danso,Ahrns, LoluHadjh S. 342,298 343 Dodd,Bacchiocchi, Erin M. Antonella 612148, 606, 635 Darji,Aiba, KavitaSetsuya 161700 Dodwad,Bachelor, Shah-Johan Michael A. 559566, 647, 725 Darling,Akhtar, NosheenThomas N. 168,598 441 Doebel,Bae, Jong Thomas H. 508660 Das,Al-Sadek, Lopa Camli 726582 Dolly,Baek, Naomi Yoosang 081198 Dasgupta,Alberico, StephanieAmrita 585084 Domloge,Baer, Janina Nouha 354,679 355, 356, 357, 358, 627 Daud,Albuquerque, Adil Celina 194065 Donahue,Baerenwald, Greg Devin 156138 Davari,Alessi Cesar, Parastoo Sabrina 074,250 170 Dong,Bagby, Chen Stacey 507624 David,Alexeev, Gloria Vitali 193,652 350 Dong,Baghdadi, Chengguo T 367692 David,Algazi, Michael Alain 457194 Dong,Bai, JingHangming 729088 Davies,Ali, Niwa Kelvin 713675 Dong,Baida, Kelly Gleb 393491 Davies,Alijarde, Michael Roberto 625275 Donigan,Bailey, IreneJessica M. 191,174 233 Davis,Alkelai, Angela A L. 650066 Doong,Bak, Soon-Sun Judy 312659 Davis,Ally, Mina Rachel S. 558132, 174, 315 Doppler,Bakshi, StephanPooja 364396 Dayal,Almeida, Jasbani Adam R. 486648 Dorrestein,Ballard, David Peter H. 193536 deAlshehri, Almeida, Wedad Amanda 525173 Dorsey,Balooch, Jean Guive 156249 deAlves, Belilovsky, Paul Clarence 197056 Dotto,Banez, Gian Lionel Paolo 121,251 122 DeAlvim, Benedetto, Rafael Anna 213,316, 346, 317, 350 318 Dou,Banga, Zhixun Ajay K. 156063, 338, 362, 396 deAmagai, Carvalho, Masayuki Camila M. 363098, 352, 508 Douglas,Bao, Xiaomin Stephanie 436451 deAmbrose, Guzman Jeffery Strong, J. Cristina 452536 Douki,Bar-Hen, Thierry Avner 606,269 635 deAmin, Jong, Ahmad Annemieke S. 019260 Doumani,Baratti, Mariana Ryan 256525 deAmoh, Thomaz, Yasuyuki Andre 525691 Doveikis,Barcellos-Hoff, Julia Mary Helen 203580 deAnandasabapathy, Tollenaere, Morgane Niroshana 718003, 004, 007 Drake,Bardot, Adam Evan 156680 DeAnderson, Vuyst, Évelyne Abraham 335281 Drew,Barkoukis, Ben Hope 182214 Drill, Esther 448 Debanne,Anderson, Sarah Mark S. 214028 Barnes, Drew H. 552 Debashis, Reja 308 Drury, Kerry E. 320 Anderson, Mary E. 511 Barnes, Kathleen 350 Degan, Simone 040 Du, Tiankai 205, 269 Andl, Claudia D. 711, 735 Baron, Elma D. 584 Degrave, Veronique 380 Dubaz, Ornella 514 Andl, Thomas 711, 735 Barthel, Steven R. 004 Del Rio, Marcela 151 Duculan, Judilyn F. 281, 445 Andre-Frei, Valerie 380, 485, 542 Barzegar, Mohammad R. 464, 466 Delaney, Martha 256 Dudley, Joel 491 Andrews, J. 259, 395, 705, 730, 733 Barzilai, A 066 Dellavalle, Robert 270, 291, 300, 307, 313, 333 Duggan, Chelsea 229 Angra, Divya 112 Basel-Vanagaite, Lina 457 Delost, Gregory R. 212, 267, 332 Duncan, Nathan 129, 223 Ansell, David 666 Bashir, Hasan 149 Delost, Maria E. 212, 267 Dunnick, Cory 300 Antaya, Richard 436 Bashir, Muhammad 056, 067 DeLouise, Lisa A. 024 Duo, Lina 456 Antes, Travis 130 Bashkirova, Elizaveta 428 Demehri, Shadmehr 021 Duperret, Elizabeth K. 474 Aplin, Andrew 107 Basiri, M R. 464 Denardo, David 021 Duszynski, Robert J. 138 Arave, Rowan 625 Bastien, Philippe 249 Denda, Mitsuhiro 377 Dutz, Jan P. 086, 449 Arbieva, Zarema 567 Batazzi, Adriana 144 Denda, Sumiko 377 Duvic, Madeleine 019, 079, 101, 179, 264, 423 Arbiser, Jack L. 063, 176, 495 Baudouin, Caroline 197, 369 Deng, Jingwen 093 Deng,Arcaroli, Liang John J. 570624 Bauer, Jürgen 136 Archer, Nate 510 Baum, S 066 www.jidonline.org S131 S128 Journal of Investigative Dermatology (2015), Volume 135 103 AUTHOR INDEX AUTHOR INDEX

Arcioni, Marianne 356 Feder, Rachel E. 003 A E Aasi, Sumaira Z. 209 Ardeleanu, Marius 169 Eash, Kyle 038 Feeney, Luz 613 Abaci, Hasan E. 401, 427, 715 Arenas, Elsa 224, 230 Eberlin, Livia S. 209 Feingold, Kenneth 381 Abbas, Abul K. 011, 016, 029, 034, 675 Ariizumi, Kiyoshi 096, 199 Eby, Jonathan 047 Feldman, Ron J. 046, 061, 479 Abbas, Tazeen 229 Armento, Alexander 566, 725 Eckert, Richard 143, 389, 460 Feldstein, Stephanie 207 Abdel-Malek, Zalfa A. 607 Armile, James A. 212 Eckes, Beate 484 Felsen, Diane 698 Abdelgawwad, Mohammad 582 Armstrong, April W. 246, 303 Eckhart, Leopold 388, 390 Femia, Alisa N. 242, 279, 290 Abdul-Wahab, Alya 411 Armstrong, Cheryl A. 520 Edelson, Richard 031, 222 Feng, Cheng 456 Abe, Riichiro 361 Arnold, Steven E. 310 Efimova, Tatiana 681 Feng, Rui 056, 202, 596 Abecasis, Goncalo 438, 440 Arozenius, Helena 006 Ehst, Benjamin D. 257, 258 Ferguson, Sara S. 298 Abels, Christoph 359 Arron, Sarah 102, 133, 384 Eichenfield, Lawrence F. 207, 219 Fernandez, Anthony P. 172 Abeni, Damiano 417 Artis, Keli 193, 350 Eide, Melody J. 287 Fernandez, Jose R. 529, 568 Achtman, Jordan C. 073 Artomov, Mykyta 134 Eilers, David 291 Ferreira, Yolene 354, 627 Adachi, Akimasa 220 Asada, Hideo 054 Eischen, Christine M. 138 Ferris, Laura 322 Adams, Peter D. 156 Asano, Yoshihide 009, 177 Eisenbrey, John R. 722 Fessing, Michael 679 Adase, Chris 337 Asgari, Maryam M. 305 Eketjall, Sanna 221 Feuchtinger, Tobias 420 Adhami, Vaqar 559 Ashbaugh, Alyssa 509, 510 Ekman, Anna-Karin 546 Fewkes, Natasha 308 Adhikary, Gautam 143, 389 Aspiroz, Carmen 189 Ekström, Gunilla 006 Figlak, Katarzyna 594 Adler, Brandon 239, 295, 531, 713 Astry, Brian 557 El Ghalbzouri, Abdoel 343 Filzwieser, Manuel 594 Admani, Shehla 219 Ata, Mohammad O. 581 El-Domyati, Moetaz 652 Finkielsztein, Ariel 399 Adotama, Prince 329 Atanasova, Velina 426 Elco, Chris 225, 262 Fiore, David 631, 724, 731 Afanasiev, Olga 015 Athar, Mohammad 150, 571, 651 Elder, James T. 248, 263, 438, 440, 446, 489 Fiorentino, David F. 064, 410 Afaq, Farrukh 571, 638 Atsugi, Toru 352 Elgart, George 657 Fireman, Bruce 305 Afshar, Maryam 207 Atwood, Scott 120, 132, 174 Eliades, Philip 636 Fischbach, Michael A. 011 Agak, George W. 407, 531 Atzmony, Lihi 457 Elias, Peter M. 102, 348, 360, 381, 389, 400 Fischer, Alexander H. 314 Agarwal, Ashwin 164, 251 Aust, Samantha 083, 084 Ellebrecht, Christoph 018, 059, 060, 071 Fischer, Heinz 388, 390 Agarwal, Priti 013 Awgulewitsch, Alexander 690 Eller, Mark 639 Fishelevich, Rita 524 Aggarwal, Rohit 050 Ayehunie, Seyoum 566 Elmets, Craig A. 581, 582, 638, 651 Fisher, David C. 421 Agón, Pedro 275 Ayithan, Natarajan 544 Emerson, Ryan O. 039, 147 Fisher, David E. 646 Ahmad, Israr 581 Azambuja, Ana P. 316, 317, 318 Eming, R 218 Fisher, Gary J. 139, 254, 492, 493 Ahmad, Nihal 654 Aziz, Ahmar 709 Enerbäck, Charlotta 546 Fisher, Hannah M. 204 Ahmed, Rehana L. 612 Epstein, Ervin 004, 116, 135 Fitzpatrick, James E. 141 Ahn, Jaewoo 198 Erdos, Geza 550 Fleckman, Philip 195 Ahn, Richard 443 Erez, N 378, 450 Florek, Aleksandra G. 246, 303 B Ahn, Sung K. 660 Babineau, Denise 350 Ericson, Marna 277, 525, 563 Florence, Tiffany C. 253, 386 Ahrns, Hadjh S. 298 Bacchiocchi, Antonella 148, 606, 635 Eriksson, Nicholas 244 Flores, E R. 110 Aiba, Setsuya 700 Bachelor, Michael A. 566, 647, 725 Ermilov, A 155 Flores, Manuel A. 469 Akhtar, Nosheen 598 Bae, Jong H. 660 Ertel, Adam 466 Florez-White, Mercedes 301 Al-Sadek, Camli 582 Baek, Yoosang 198 Ertongur-Fauth, Torsten 667 Flowers, Brttany 153 Alberico, Stephanie 084 Baer, Janina 679 Esaki, Hitokazu 036, 165 Flynn, Ryan A. 265 Albuquerque, Celina 065 Baerenwald, Devin 138 Esandrio, Jessica 160, 231 Foley, John G. 477, 736 Alessi Cesar, Sabrina 250 Bagby, Stacey 624 Eskin-Schwartz, Marina 457 Follansbee, Aaron T. 247 Alexeev, Vitali 652 Baghdadi, T 692 Esselin, Nicolas 355, 358 Forsberg, Flemming 722 Algazi, Alain 194 Bai, Jing 088 Esser, Charlotte 375 Forsyth, Alexandra M. 127 Ali, Niwa 675 Baida, Gleb 491 Esser, E. S. 045 Fortina, Paolo 466 Alijarde, Roberto 275 Bailey, Irene 174 Esteve-Puig, Rosaura 613 Foy, Thompson 582 Alkelai, A 066 Bak, Soon-Sun 659 Ettinger, Monika 016 Francisco, Schopfer J. 414 Ally, Mina S. 132, 174, 315 Bakshi, Pooja 396 Evangelista, Flor 091 Franke, Andre 431 Almeida, Adam R. 648 Ballard, David H. 536 Everts, Helen B. 665 Franks, Andrew G. 051, 279 Alshehri, Wedad 173 Balooch, Guive 249 Ewald, David A. 394 Frech, Tracy 087 Alves, Paul 056 Banez, Lionel 251 Eysteinsdottir, Jenna H. 175 Frechet, Mathilde 547 Alvim, Rafael 316, 317, 318 Banga, Ajay K. 063, 338, 362, 396 Ezhkova, Elena 680 Freeman, Bruce 414 Amagai, Masayuki 098, 352, 508 Bao, Xiaomin 451 Freeman, Theresa A. 721, 722 Ambrose, Jeffery J. 536 Bar-Hen, Avner 269 Freis, Olga 485 Amin, Ahmad S. 260 Baratti, Mariana 525 Freund, Yvonne 507 F Amoh, Yasuyuki 691 Barcellos-Hoff, Mary Helen 580 Fahmy, Tarek 031 Frias, Maria P. 189 Anandasabapathy, Niroshana 003, 004, 007 Bardot, Evan 680 Fainberg, G 378 Fridy, Sade 213, 346 Anderson, Abraham 281 Barkoukis, Hope 214 Fairfield, H 468 Friedewald, John J. 105, 158 Anderson, Mark S. 028 Barnes, Drew H. 552 Fairfield, Heather 442, 453, 455 Friedman, Adam 531, 713 Anderson, Mary E. 511 Barnes, Kathleen 350 Fairley, Janet A. 083, 084 Friedman, Blake E. 035 Andl, Claudia D. 711, 735 Baron, Elma D. 584 Falanga, Vincent 631, 724, 728, 731 Friedman, Joel 531, 713 Andl, Thomas 711, 735 Barthel, Steven R. 004 Falo, Louis D. 032, 035, 402, 414, 550 Friedrich, Emily 550 Andre-Frei, Valerie 380, 485, 542 Barzegar, Mohammad R. 464, 466 Fan, Kristi 367 Frisch, Stephanie 166 Andrews, J. 259, 395, 705, 730, 733 Barzilai, A 066 Fan, Sabrina Mai-Yi 671, 676 Fritz, Yi 033, 037, 495, 561 Angra, Divya 112 Basel-Vanagaite, Lina 457 Fang, Hui 078 Frydenlund, Noah 614 Ansell, David 666 Bashir, Hasan 149 Farber, Sara 283 Fu, Hangfei 514 Antaya, Richard 436 Bashir, Muhammad 056, 067 Farjo, Bessam 677, 678 Fu, Xiujun 041 Antes, Travis 130 Bashkirova, Elizaveta 428 Farjo, Nilofer 677, 678 Fucaloro, Stephen 123 Aplin, Andrew 107 Basiri, M R. 464 Farrell, Amanda 662 Fuchs-Telem, D 395 Arave, Rowan 625 Bastien, Philippe 249 Farshchian, Mehdi 100 Fuentes-Duculan, Judilyn B. 266, 686 Arbieva, Zarema 567 Batazzi, Adriana 144 Farwell, Gregory 170 Fuhlbrigge, Robert C. 041, 043, 147 Arbiser, Jack L. 063, 176, 495 Baudouin, Caroline 197, 369 Fawzy Rezk, Ahmed 652 Fujioka, Yoichiro 361 Arcaroli, John J. 624 Bauer, Jürgen 136 Fazel, Nasim 074, 170 Fujisawa, Akihiro 106 Archer, Nate 510 Baum, S 066 Fear, Mark 707 Fujita, Andre 363 S128 Journal of Investigative Dermatology (2015), Volume 135 S132 Journal of Investigative Dermatology (2015), Volume 135 104 AUTHOR INDEX AUTHOR INDEX

Arcioni, Marianne 356 Fujita,A HIdeki 177, 188 Girardi, Michael 125, 222, 379 Ardeleanu, Marius 169 Fujita,Aasi, SumairaMayumi Z. 106,209 624, 640, 648, 649 Giresi, Paul 451 Fujita,Abaci, Yasuyuki Hasan E. 432401, 427, 715 Girling,Arenas, Peter Elsa 476224, 230 Fukai,Abbas, Tatsuo Abul K. 716011, 016, 029, 034, 675 Gkoutos,Ariizumi, Georgios Kiyoshi V. 204096, 199 Fukami,Abbas, TazeenYasuo 621229 Glant,Armento, Tibor Alexander 567566, 725 Fukuda,Abdel-Malek, Keitaro Zalfa A. 098607 Glass,Armile, Donald James A. A. 329,212 447 Fukumoto,Abdelgawwad, Takeshi Mohammad 621582 Glatz,Armstrong, Martin April W. 180,246, 508 303 Fukunaga-Kalabis,Abdul-Wahab, Alya Mizuho 646411 Gledhill,Armstrong, Karl Cheryl A. 401,520 427, 715 Funakoshi,Abe, Riichiro Takeru 098361 Glick,Arnold, S. A. Steven E. 344310 Furniss,Abecasis, Megan Goncalo 238,438, 272 440 Gober,Arozenius, Michael Helena 149,006 157 Furukawa,Abels, Christoph Fukumi 062359 Gochnauer,Arron, Sarah Heather 685102, 133, 384 Furukawa,Abeni, Damiano Louise K. 418417 Goggins,Artis, Keli William 134193, 350 Achtman, Jordan C. 073 Goldberg,Artomov, I Mykyta 066,134 378, 450 Adachi, Akimasa 220 Golden,Asada, JackelynHideo B. 033,054 037, 278, 501 GAdams, Peter D. 156 Goldsmith,Asano, Yoshihide T. 378009, 177 Gadek,Adase, ThomasChris 001337 Goldstein,Asgari, Maryam Nathaniel M. B. 641305 Gaide,Adhami, Olivier Vaqar 039559 Gondran,Ashbaugh, Catherine Alyssa 354,509, 627 510 Gaiser,Adhikary, Maria Gautam R. 241143, 389 Gonzalez,Aspiroz, CarmenAlfredo 629189 Gajjala,Adler, Brandon Abhinay 409239, 295, 531, 713 Gonzalez,Astry, Brian Juana 036,557 055, 165, 698 Galimberti,Admani, Shehla Fabrizio 172,219 278 Gonzalez,Ata, Mohammad Salvador O. 151,581 583 Gallagher,Adotama, KatherinePrince 263329 González,Atanasova, Javier Velina 224426 Gallo,Afanasiev, Richard Olga L. 193,015 282, 337, 513, 522, 543, 702 Goodrich,Athar, Mohammad Jane K. 631150, 571, 651 Gan,Afaq, David Farrukh 253,571, 386 638 Goodwin,Atsugi, Toru Zane 452352 Ganesh,Afshar, MaryamSanthi 263207 Gopaul,Atwood, Remona Scott 433120, 132, 174 Gao,Agak, Bifeng George W. 641407, 531 Gordon,Atzmony, Derek Lihi 118457 Gao,Agarwal, Lin Ashwin 383164, 251 Gordon,Aust, Samantha Elisa J. 158083, 084 Gao,Agarwal, Tianwen Priti 075,013 319, 456, 619, 645 Gordon,Awgulewitsch, Joel S. Alexander 529,690 568 Gao,Aggarwal, Wenshan Rohit 288050 Gorell,Ayehunie, Emily Seyoum 418566 Gao,Agón, Xiang Pedro 324275 Goren,Ayithan, Andy Natarajan 672544 Garbe,Ahmad, Claus Israr 420581 Gormley,Azambuja, Anna Ana P. 097316, 317, 318 Garcet,Ahmad, Sandra Nihal 042,654 280 Gornowicz-Porowska,Aziz, Ahmar Justyna 285709 Garcia,Ahmed, Andrea Rehana L. 702612 Gorpas, Dimitris 170 Garcia,Ahn, Jaewoo Imane 356198 Goruppi, Sandro G. 122 Garcia-Doval,Ahn, Richard Ignacio 189443 Goto,B Makiko 377 García-Malinis,Ahn, Sung K. Ana J 275660 Gotow,Babineau, Erica Denise 245350 Gardner,Ahrns, Hadjh Sue E. S. 533298 Gottlieb,Bacchiocchi, Alice B.Antonella 406148, 606, 635 Gareau,Aiba, Setsuya Daniel 049700 Goubran,Bachelor, Bishoy Michael A. 381566, 647, 725 Garrett-Mayer,Akhtar, Nosheen Elizabeth 047598 Goummih,Bae, Jong SalmaH. 269660 Garrity,Al-Sadek, Ryan Camli 629582 Goyarts,Baek, Yoosang Earl C. 630198 Garza,Alberico, Luis Stephanie A. 365,084 599 Grachtchouk,Baer, Janina M 155679 Gaspari,Albuquerque, Anthony Celina 524065 Gracia-Cazaña,Baerenwald, Devin Tamara 583138 Gat,Alessi A Cesar, Sabrina 450250 Grafi-Cohen,Bagby, Stacey M 378624 Gaydon,Alexeev, Amandine Vitali 485652 Graham,Baghdadi, Neil T 169692 Ge,Algazi, Rui Alain 645194 Grandhi,Bai, Jing Radhika 160,088 231, 250 Gearty,Ali, Niwa Sofia V. 011,675 016, 029 Gransheier,Baida, Gleb Diana 136491 Geha,Alijarde, Raif Roberto 510275 Granstein,Bailey, Irene Richard D. 020,174 226, 516, 532 Gehad,Alkelai, Ahmed A 026,066 072, 082, 225, 415, 421 Gray,Bak, Jayla Soon-Sun 036,659 165 Gelfand,Ally, Mina Joel S. 203,132, 289, 174, 302, 315 310 Gray,Bakshi, Linda Pooja 210396 Geller,Almeida, Alan Adam R. 322648 Gray,Ballard, Nathanael David H.S. 636536 Geller,Alshehri, S Wedad 066,173 218 Greco,Balooch, Valentina Guive 119,249 404, 674 George,Alves, Paul Jasmine 654056 Green,Banez, Adam Lionel H. 536251 Geraci,Alvim, RafaelMark 106316, 317, 318 Green,Banga, Gary Ajay K. 613063, 338, 362, 396 Gerstenblith,Amagai, Masayuki Adam 245098, 352, 508 Green,Bao, XiaominKathleen J. 105,451 378, 475 Gerstenblith,Ambrose, Jeffery Meg J. R. 245,536 292, 326 Green,Bar-Hen, Russell Avner 625269 Geskin,Amin, Ahmad Larisa S. 294260 Greenstein,Baratti, Mariana Ian 442525 Gesumaria,Amoh, Yasuyuki Lisa 602691 Grenier,Barcellos-Hoff, Stephane Mary Helen 380580 Getsios,Anandasabapathy, Spiro Niroshana 399,003, 473, 004, 723 007 Grénman,Bardot, Evan Reidar 100680 Grether-Beck, Susanne 375 Ghadially,Anderson, RubyAbraham 384281 Barkoukis, Hope 214 Grice, Elizabeth A. 533, 553, 554 Ghahary,Anderson, Aziz Mark S. 673028 Barnes, Drew H. 552 Ghannoum, Mahmoud 215 Grichnik, James M. 639 Anderson, Mary E. 511 Barnes, Kathleen 350 Ghaznavi, A 692 Griffith, Alexis 558 Andl, Claudia D. 711, 735 Baron, Elma D. 584 Gho, Deborah Stephanie 409 Griffiths, Christopher E. 387 Andl, Thomas 711, 735 Barthel, Steven R. 004 Ghoreishi, Mehran 086 Grigoryan, Konstantin 270, 333 Andre-Frei, Valerie 380, 485, 542 Barzegar, Mohammad R. 464, 466 Ghosh, Manju 438 Grillari, Johannes 594 Andrews, J. 259, 395, 705, 730, 733 Barzilai, A 066 Gibbons, Simon 372 Groft, Sarah G. 278, 501 Angra, Divya 112 Basel-Vanagaite, Lina 457 Gibson, Juliet F. 222, 379 Grossmann, Allie 625 Ansell, David 666 Bashir, Hasan 149 Gibson, Lawrence 243 Gruber, Florian 594 Antaya, Richard 436 Bashir, Muhammad 056, 067 Gilaberte, Yolanda 151, 189, 275, 583 Grun, Dan 143 Antes, Travis 130 Bashkirova, Elizaveta 428 Giljohann, David 413 Gu, Lihong 365 Aplin, Andrew 107 Basiri, M R. 464 Gill, Liza 287 Gubens, Matthew 194 Arave, Rowan 625 Bastien, Philippe 249 Gilleaudeau, Patricia 190 Gudjonsson, Johann E. 263, 399, 440, 446, 552, 723 Arbieva, Zarema 567 Batazzi, Adriana 144 Gillette, Brian 401, 427, 715 Guerrero-Juarez, Christian F. 522 Arbiser, Jack L. 063, 176, 495 Baudouin, Caroline 197, 369 Gilmore, Elaine 008 Guilabert, Antonio 091 Giltaire,Arcaroli, Séverine John J. 335624 Gujjar,Bauer, Meera Jürgen 063136 Archer, Nate 510 Baum, S 066 www.jidonline.org S133 S128 Journal of Investigative Dermatology (2015), Volume 135 105 AUTHOR INDEX AUTHOR INDEX

Arcioni, Marianne 356 Gulati, Nicholas 192 He, Yu-Ying 107, 347, 580 A Aasi, Sumaira Z. 209 Ardeleanu, Marius 169 Gulewicz, Kara J. 452 Hedin, Cristy 566 Abaci, Hasan E. 401, 427, 715 Arenas, Elsa 224, 230 Gunaratne, P 110 Hedlin, Haley 315 Abbas, Abul K. 011, 016, 029, 034, 675 Ariizumi, Kiyoshi 096, 199 Guo, Changxiong 535 Hein, Molly S. 050 Abbas, Tazeen 229 Armento, Alexander 566, 725 Guo, Claire 516 Held, Matthew A. 632 Abdel-Malek, Zalfa A. 607 Armile, James A. 212 Guo, Sen 456 Helfenberger, Joseph 084 Abdelgawwad, Mohammad 582 Armstrong, April W. 246, 303 Guo, Zongyou 401, 419, 427, 715 Heppt, Markus 646 Abdul-Wahab, Alya 411 Armstrong, Cheryl A. 520 Gupta, Kalpna 525 Herlyn, Meenhard 646 Abe, Riichiro 361 Arnold, Steven E. 310 Gupta, Rashmi 443 Hernández-Martin, Angela 275 Abecasis, Goncalo 438, 440 Arozenius, Helena 006 Gupta, Sameer 134 Heron, Alain 376 Abels, Christoph 359 Arron, Sarah 102, 133, 384 Gutierrez, Albert 235 Hertl, M 218 Abeni, Damiano 417 Artis, Keli 193, 350 Gutiérrez, Manuel 224 Hibino, Toshihiko 368 Achtman, Jordan C. 073 Artomov, Mykyta 134 Guttman-Yassky, Emma 036, 042, 055, 085, 165, 255, 280, 350, Higgins, Claire 401, 427, 682 Adachi, Akimasa 220 Asada, Hideo 054 394, 452, 562, 686 Higgs, Brandon 221 Adams, Peter D. 156 Asano, Yoshihide 009, 177 Hill, Zelee 348 Adase, Chris 337 Asgari, Maryam M. 305 Hinds, David 244 Adhami, Vaqar 559 Ashbaugh, Alyssa 509, 510 Hinds, Ginette A. 160, 231 H Adhikary, Gautam 143, 389 Aspiroz, Carmen 189 Ha, Linan 142 Hines, Michelle D. 253, 386 Adler, Brandon 239, 295, 531, 713 Astry, Brian 557 Haarmann-Stemmann, Thomas 589 Hirano, Takashige 352 Admani, Shehla 219 Ata, Mohammad O. 581 Haas, Katharina 375 Hiroyasu, Sho 703 Adotama, Prince 329 Atanasova, Velina 426 Hachiya, Yuko 368 Ho, Roger 211, 237 Afanasiev, Olga 015 Athar, Mohammad 150, 571, 651 Hadgraft, J. 569 Hoaglin, Laura 641 Afaq, Farrukh 571, 638 Atsugi, Toru 352 Hadiono, Matthew 558 Hobbs, Ryan 144 Afshar, Maryam 207 Atwood, Scott 120, 132, 174 Hagstrom, Erika L. 300 Hodak, Emmilia 457 Agak, George W. 407, 531 Atzmony, Lihi 457 Hahn, Hyomi 520 Hodges, James 277 Agarwal, Ashwin 164, 251 Aust, Samantha 083, 084 Haitz, Karyn 004, 007 Hodgetts, Stuart 707 Agarwal, Priti 013 Awgulewitsch, Alexander 690 Halaban, Ruth 148, 606, 635 Hodkinson, Brendan P. 533, 553, 554 Aggarwal, Rohit 050 Ayehunie, Seyoum 566 Hale, Christopher S. 664 Hoehndorf, Robert 204 Agón, Pedro 275 Ayithan, Natarajan 544 Hall, Russell P. 164, 251 Hoffman, Robert M. 691 Ahmad, Israr 581 Azambuja, Ana P. 316, 317, 318 Hamilton, Jennifer 169 Hogan, Daniel 291 Ahmad, Nihal 654 Aziz, Ahmar 709 Hamm, David 192 HogenEsch, Harm 439 Ahmed, Rehana L. 612 Hamm, Gregory 376 Holahan, Heather M. 083 Ahn, Jaewoo 198 Hammers, Christoph M. 018, 060 Hollander, Christine 137 Ahn, Richard 443 Hammond, Margaret 215 Holleran, Walter M. 102 B Ahn, Sung K. 660 Babineau, Denise 350 Hamon, Sara 169 Holmen, Sheri 625 Ahrns, Hadjh S. 298 Bacchiocchi, Antonella 148, 606, 635 Hamzavi, Iltefat H. 287, 582 Holton, Katherine 487, 642 Aiba, Setsuya 700 Bachelor, Michael A. 566, 647, 725 Han, Alex 617 Honda, Kord 245, 292, 332 Akhtar, Nosheen 598 Bae, Jong H. 660 Han, Chang-xu 012, 587 Hong, Chien-Hui 103, 523 Al-Sadek, Camli 582 Baek, Yoosang 198 Han, Jiali 324 Hong, Enping 031 Alberico, Stephanie 084 Baer, Janina 679 Han, Ju Hee 540 Hong, Seung P. 660 Albuquerque, Celina 065 Baerenwald, Devin 138 Han, Ling 093 Hong, Young-Kwon 734 Alessi Cesar, Sabrina 250 Bagby, Stacey 624 Han, Minerva 144 Hook, Kristen 408 Alexeev, Vitali 652 Baghdadi, T 692 Han, Mira 482 Hooten, Joanna 251 Algazi, Alain 194 Bai, Jing 088 Han, Seunghyun 365 Hoover, Paul 723 Ali, Niwa 675 Baida, Gleb 491 Han, Yunlin 687 Hopkinson, Susan B. 714 Alijarde, Roberto 275 Bailey, Irene 174 Hanifin, Jon 350 Hordinsky, Maria 019, 079, 247, 264, 277, 408 Alkelai, A 066 Bak, Soon-Sun 659 Hanlon, Douglas 031 Horimoto, Andrea R. 316, 317, 318 Ally, Mina S. 132, 174, 315 Bakshi, Pooja 396 Hannigan, Geoffrey D. 553, 554 Horiuchi, Keisuke 508 Almeida, Adam R. 648 Ballard, David H. 536 Hanson, Brooke 277 Horrell, Jeremy 685 Alshehri, Wedad 173 Balooch, Guive 249 Harberts, Erin 524 Horsley, Valerie 478, 662, 694 Alves, Paul 056 Banez, Lionel 251 Harden, Jamie L. 049, 190, 192 Horswill, Alex 545 Alvim, Rafael 316, 317, 318 Banga, Ajay K. 063, 338, 362, 396 Harel, Sivan 682, 720 Horton, Karen 384 Amagai, Masayuki 098, 352, 508 Bao, Xiaomin 451 Harker, David B. 096, 199 Horwinski, Joseph 533 Ambrose, Jeffery J. 536 Bar-Hen, Avner 269 Harms, KL 155 Hosam El-Din, Wael 652 Amin, Ahmad S. 260 Baratti, Mariana 525 Harms, Paul W. 552 Hossain, M. Zulfiquer 365 Amoh, Yasuyuki 691 Barcellos-Hoff, Mary Helen 580 Harper, Josephine Stacey 531 Hou, Yingping 490, 712 Anandasabapathy, Niroshana 003, 004, 007 Bardot, Evan 680 Harries, Matthew 666 Hovnanian, Alain 405, 408 Anderson, Abraham 281 Barkoukis, Hope 214 Harris, Adam G. 228 Hristova, Denitsa 646 Anderson, Mark S. 028 Barnes, Drew H. 552 Harris, Belinda S. 442, 455 Hsin-Su, Yu 523 Anderson, Mary E. 511 Barnes, Kathleen 350 Harris, John E. 013 Hu, Hai 689 Andl, Claudia D. 711, 735 Baron, Elma D. 584 Harris-Tryon, Tamia 160, 231 Hu, Ronghua 444 Andl, Thomas 711, 735 Barthel, Steven R. 004 Hasegawa, Toshio 716 Hu, Xuguang 281 Andre-Frei, Valerie 380, 485, 542 Barzegar, Mohammad R. 464, 466 Hashimoto, Takanori 621 Hu, Yaping 499 Andrews, J. 259, 395, 705, 730, 733 Barzilai, A 066 Hastings, Justin G. 027 Hu, Yiyao 456 Angra, Divya 112 Basel-Vanagaite, Lina 457 Hastings, Karen T. 028 Huang, Andrew 149 Ansell, David 666 Bashir, Hasan 149 Hata, Tissa 193, 282, 522 Huang, Chun-Ming 014, 513, 537, 539 Antaya, Richard 436 Bashir, Muhammad 056, 067 Hatzis, Christofer 229 Huang, Jing 222 Antes, Travis 130 Bashkirova, Elizaveta 428 Haughey, Mary 168 Huang, Meei-Li 256 Aplin, Andrew 107 Basiri, M R. 464 Havran, Wendy 040 Huang, Min 592 Arave, Rowan 625 Bastien, Philippe 249 Hayden, Matthew S. 511, 620, 628 Huang, Shu-Mei 701 Arbieva, Zarema 567 Batazzi, Adriana 144 Hayden, Patrick J. 725 Huang, Victor 026, 072, 415 Arbiser, Jack L. 063, 176, 495 Baudouin, Caroline 197, 369 Haynes, Kevin 310 Huang, Wen-Yen 670 Arcaroli, John J. 624 Bauer, Jürgen 136 He, Donggou 591 Huang, Zhi-ming 622 Archer, Nate 510 Baum, S 066 He, Tianyuan 492, 493 Huber, Kristen L. 529, 568 S128 Journal of Investigative Dermatology (2015), Volume 135 S134 Journal of Investigative Dermatology (2015), Volume 135 106 AUTHOR INDEX AUTHOR INDEX

Arcioni, Marianne 356 Huda,A Sumeira 582 Jensen, Liselotte 514 Ardeleanu, Marius 169 Huet-Adams,Aasi, Sumaira Beverley Z. 186209 Jeon, Jiehyun 198 Hughes,Abaci, Hasan Michael E. W. 717401, 427, 715 Jeong,Arenas, Joseph Elsa S. 092224, 230 Hüls,Abbas, Anke Abul K. 286,011, 288, 016, 293 029, 034, 675 Jeong,Ariizumi, Sam Kiyoshi 276096, 199 Hupe,Abbas, Melanie Tazeen 348,229 360, 400 Jeong,Armento, Se Kyoo Alexander 515,566, 660 725 Hurliman,Abdel-Malek, Elisabeth Zalfa A. 247607 Jhaveri,Armile, Mamta James A. 236212 Hwang,Abdelgawwad, Bin-Jin Mohammad 152,582 494 Ji,Armstrong, Zhenyu April W. 616246, 303 Hwang,Abdul-Wahab, Cheng Alya 385411 Jia,Armstrong, Peilin Cheryl A. 138520 Hwang,Abe, Riichiro Joonsung 097361 Jian,Arnold, Zhe Steven E. 319,310 619 Hwang,Abecasis, Sam Goncalo 126,438, 517, 440 534, 544 Jiang,Arozenius, Man Helena 012,006 383 Abels, Christoph 359 Jiang,Arron, Q. Sarah 426102, 133, 384 Abeni, Damiano 417 Jiang,Artis, Ting-Xin Keli 717193, 350 IAchtman, Jordan C. 073 Jiang,Artomov, Xiaodong Mykyta 039,134 041, 147 Ibbetson,Adachi, Akimasa Jan 538220 Jimenez,Asada, HideoJoaquin 610,054 657 Ibrani,Adams, Dafina Peter D. 015156 Jin,Asano, Cheng Yoshihide Long 482009, 177 Idkowiak-Baldys,Adase, Chris Jolanta 385337 Jin,Asgari, Guang Maryam C. M. 115305 Igawa,Adhami, Ken Vaqar 564559 Jin,Ashbaugh, Li Alyssa 288,509, 293 510 Igoucheva,Adhikary, GautamOlga 652143, 389 Jin,Aspiroz, Liang Carmen 012,189 587 Iida,Adler, Hideo Brandon 716239, 295, 531, 713 Jin,Astry, Seon-PIL Brian 217,557 481, 601 Ikeda,Admani, Shigaku Shehla 526,219 716 Jin,Ata, Shan Mohammad O. 017,581 252, 556, 732 Ikeya,Adotama, Shigeki Prince 588329 Jin,Atanasova, X Velina 497426 Ikushima,Afanasiev, Hiroaki Olga 504015 Jin,Athar, Zhe HuMohammad 482150, 571, 651 Ilag,Afaq, Leopold Farrukh 549571, 638 Jo,Atsugi, Seunghee Toru 121352 Im,Afshar, Michelle Maryam 496207 Johnson,Atwood, Jodi Scott L. 105120, 132, 174 Imai,Agak, Takashi George W. 500407, 531 Johnson,Atzmony, Keith Lihi 488457 Imai,Agarwal, Yasutomo Ashwin 517,164, 534, 251 544 Johnson,Aust, Samantha Kelly 118083, 084 Imamura,Agarwal, TakeshiPriti 472013 Johnson,Awgulewitsch, Mary Ann Alexander 246690 Imanishi,Aggarwal, Hisayoshi Rohit 666050 Johnson,Ayehunie, Timothy Seyoum R. 254566 Imfeld,Agón, PedroDominik 364275 Johnson-Huang,Ayithan, Natarajan Leanne 049544 Immaneni,Ahmad, Israr Supriya 308581 Johnston,Azambuja, Andrew Ana P. 175,316, 263, 317, 399, 318 446, 530, 552 Inaba,Ahmad, Yutaka Nihal 062654 Jones,Aziz, Evan Ahmar 649709 Ing,Ahmed, Lauren Rehana A. L. 133612 Jones, Evan C. 141, 687 Inoue,Ahn, Jaewoo Mai 700198 Jones, Jonathan 703, 714 Inozume,Ahn, Richard Takashi 002443 Jones,B Kenneth 641 Irmler,Ahn, Sung Martin K. 646660 Jones,Babineau, Leslie Denise 688350 Irvine,Ahrns, A Hadjh S. 378298 Jones,Bacchiocchi, Wendell Antonella 452148, 606, 635 Isakov,Aiba, Setsuya O 450700 Jonsson,Bachelor, Charlotte Michael A. 549566, 647, 725 Isedeh,Akhtar, Prescilia Nosheen N. 582598 Jonsson,Bae, Jong Goran H. 616660 Ishida-Yamamoto,Al-Sadek, Camli A 378582 Joo,Baek, Sarah Yoosang 312198 Ishitsuka,Alberico, Yosuke Stephanie 366084 Joseph,Baer, JaninaA K. 110679 Isseroff,Albuquerque, Roslyn CelinaR. 577065 Jost,Baerenwald, Christina Devin 667138 Ito,Alessi Mayumi Cesar, Sabrina 664,250 689 Joubert,Bagby, Margot Stacey C. 123624 Itoh,Alexeev, Yoshiko Vitali 564652 Joung,Baghdadi, Keith T 435692 Iwamoto,Algazi, Alain Satori 498194 Jourdain,Bai, Jing Roland 269088 Iwasaki,Ali, Niwa Tetsushi 621675 Juarranz,Baida, Gleb Angeles 151,491 583 Iwatsuki,Alijarde, KeijiRoberto 551275 Justiniano,Bailey, Irene Jeanine 629174 Iyer,Alkelai, Jayasri A G. 015066 Justiniano,Bak, Soon-Sun Rebecca 609659 Iyer,Ally, Matthew Mina S. K. 440132, 174, 315 Bakshi, Pooja 396 Izuhara,Almeida, Kenji Adam R. 098648 Ballard, David H. 536 Izumiya,Alshehri, Yoshihiro Wedad 074173 KBalooch, Guive 249 Alves, Paul 056 Kabasawa,Banez, Lionel Miyoko 177251 Alvim, Rafael 316, 317, 318 Kabashima,Banga, Ajay Kenji K. 085,063, 206, 338, 394 362, 396 JAmagai, Masayuki 098, 352, 508 Kabra,Bao, XiaominMadhulika 438451 Jabbari,Ambrose, Ali Jeffery J. 019,536 079, 089, 090, 238, 264, 272, 459 Kadiyirire,Bar-Hen, TendaiAvner 411269 Jackow,Amin, Ahmad Joanna S. 405260 Kadono,Baratti, TakafumiMariana 009,525 177 Jacob,Amoh, Justin Yasuyuki 144691 Kagha,Barcellos-Hoff, Karen Mary Helen 403580 Jacob,Anandasabapathy, Sharon Niroshana 291003, 004, 007 Kähäri,Bardot, Veli-Matti Evan 100680 Jacobe,Anderson, Heidi Abraham 181281 Kahlenberg,Barkoukis, JHope M. 552214 Jacobsen,Anderson, Gordon Mark S. 287028 Kajita,Barnes, Ai Drew H. 551552 Jagdeo,Anderson, Jared Mary R. E. 577511 Kajiya,Barnes, Kentaro Kathleen 471350 Jain, Swaranjali V. 228 Kalahasti, Geetha 253, 386 Andl, Claudia D. 711, 735 Baron, Elma D. 584 Jaju, Prajakta 135, 425 Kalia, Sunil 331 Andl, Thomas 711, 735 Barthel, Steven R. 004 Jalili, Reza 673 Kalthoff, F 416 Andre-Frei, Valerie 380, 485, 542 Barzegar, Mohammad R. 464, 466 Jammayrac, Odette 269 Kam, Sarah 232, 731 Andrews, J. 259, 395, 705, 730, 733 Barzilai, A 066 Jang, Min Soo 160, 231 Kamata, Yayoi 340, 519 Angra, Divya 112 Basel-Vanagaite, Lina 457 Janssens, Michelle 343 Kamberov, Yana 696 Ansell, David 666 Bashir, Hasan 149 Jarnagin, Kurt 507 Kan, Haidong 288 Antaya, Richard 436 Bashir, Muhammad 056, 067 Jatana, Samreen 024 Kanazawa, Nobuo 062 Antes, Travis 130 Bashkirova, Elizaveta 428 Jay, Steve 142 Kang, Hyun M. 440 Aplin, Andrew 107 Basiri, M R. 464 Jayanthy, Ashika 470 Kang, Richard 413 Arave, Rowan 625 Bastien, Philippe 249 Jayaorakash, Priyamvada 729 Kang, Sewon 160, 231, 250, 274, 312, 314, 365, 599 Arbieva, Zarema 567 Batazzi, Adriana 144 Je, Jeong Hwan 512 Kao, Ming-Shan 513 Arbiser, Jack L. 063, 176, 495 Baudouin, Caroline 197, 369 Jeanmaire, Christine 336 Kao, Stephanie 407, 531 Arcaroli, John J. 624 Jee, Shiou-Hwa 109, 633 Kapelow,Bauer, Jürgen Rachel 162136 Archer, Nate 510 Baum, S 066 www.jidonline.org S135 S128 Journal of Investigative Dermatology (2015), Volume 135 107 AUTHOR INDEX AUTHOR INDEX

Arcioni, Marianne 356 Kaplan, Daniel 508, 521, 557 Kim, Richard 406 A Aasi, Sumaira Z. 209 Ardeleanu, Marius 169 Kaplan, Mariana 203 Kim, Su Hwan 515 Abaci, Hasan E. 401, 427, 715 Arenas, Elsa 224, 230 Kaplan, Mark H. 048 Kim, Sung Hee 512 Abbas, Abul K. 011, 016, 029, 034, 675 Ariizumi, Kiyoshi 096, 199 Kaplan, Nihal 723 Kim, Sung Soo 217 Abbas, Tazeen 229 Armento, Alexander 566, 725 Kappes, John C. 638 Kim, Sung Woo 515 Abdel-Malek, Zalfa A. 607 Armile, James A. 212 Kapphahn, Kristopher 315 Kim, Tae H. 658 Abdelgawwad, Mohammad 582 Armstrong, April W. 246, 303 Karakawa, Masaru 220 Kim, Tae-Kang 345 Abdul-Wahab, Alya 411 Armstrong, Cheryl A. 520 Karia, Pritesh 182 Kim, TaeWon 618 Abe, Riichiro 361 Arnold, Steven E. 310 Karimkhani, Chante 300, 313, 333 Kim, Yeon Kyung 483 Abecasis, Goncalo 438, 440 Arozenius, Helena 006 Karlberg, Ann-Therese 549 Kim, Young Il 102 Abels, Christoph 359 Arron, Sarah 102, 133, 384 Karlsson, Isabella 495, 549 KIM, SeoHyeong 017, 252, 556, 732 Abeni, Damiano 417 Artis, Keli 193, 350 Karner, Susanne 594 Kimball, Alexa B. 233 Achtman, Jordan C. 073 Artomov, Mykyta 134 Karst, S Y. 468 Kimura, Makoto 575 Adachi, Akimasa 220 Asada, Hideo 054 Karst, Son Yong 454, 455 King, Lloyd E. 204, 052, 439, 661 Adams, Peter D. 156 Asano, Yoshihide 009, 177 Kashem, Sakeen W. 521 King, Megan 694 Adase, Chris 337 Asgari, Maryam M. 305 Kaskas, Nadine M. 536 Kingman, Joshua 395, 422 Adhami, Vaqar 559 Ashbaugh, Alyssa 509, 510 Kasko, Andrea 407 Kirby, Joslyn 273, 296, 297, 298, 309, 328 Adhikary, Gautam 143, 389 Aspiroz, Carmen 189 Kaspar, Roger 469 Kircher, David 625 Adler, Brandon 239, 295, 531, 713 Astry, Brian 557 Kasuya, Saori 208 Kirkwood, John 322 Admani, Shehla 219 Ata, Mohammad O. 581 Katdare, Meena 585, 684 Kirsanov, Kirill 491 Adotama, Prince 329 Atanasova, Velina 426 Kathuria, Parul 327 Kirsch, Ilan 225 Afanasiev, Olga 015 Athar, Mohammad 150, 571, 651 Katiyar, Santosh K. 578, 579, 581, 591 Kiss, Alexi 681 Afaq, Farrukh 571, 638 Atsugi, Toru 352 Kaur, Manjinder 640 Kitagawa, Hiroshi 137 Afshar, Maryam 207 Atwood, Scott 120, 132, 174 Kaur, Simarna 499 Kitoh, Akihiko 206 Agak, George W. 407, 531 Atzmony, Lihi 457 Kavanagh, Ann 210 Kittipongdaja, Wasakorn T. 117, 126 Agarwal, Ashwin 164, 251 Aust, Samantha 083, 084 Kavanaugh, Jeffery S. 545 Klarquist, Jared 047 Agarwal, Priti 013 Awgulewitsch, Alexander 690 Kavand, Sima 243 Klausner, Mitchell 566, 647, 725 Aggarwal, Rohit 050 Ayehunie, Seyoum 566 Kawaguchi, Makiko 177, 188 Klechevsky, Eynav 025 Agón, Pedro 275 Ayithan, Natarajan 544 Kawakami, Yutaka 002 Kleffel, Sonja 123 Ahmad, Israr 581 Azambuja, Ana P. 316, 317, 318 Kawasaki, Hiroshi 352 Klein, Rebecca 306 Ahmad, Nihal 654 Aziz, Ahmar 709 Keene, Douglas R. 408, 418 Klein, Sarah 734 Ahmed, Rehana L. 612 Keiser, Elizabeth 315 Klekotka, Paul 281 Ahn, Jaewoo 198 Keller, Christopher C. 212 Klenotic, Philip 530 Ahn, Richard 443 Keller, Matthew S. 259, 395 Klint, Cecilia 006 B Ahn, Sung K. 660 Babineau, Denise 350 Kellett, Meghan D. 097 Klover, Peter 441 Ahrns, Hadjh S. 298 Bacchiocchi, Antonella 148, 606, 635 Kelly-Scumpia, Kindra 572, 574 Kluz, Thomas 602 Aiba, Setsuya 700 Bachelor, Michael A. 566, 647, 725 Kennedy, Victoria E. 052, 439, 661 Knaggs, Helen 265, 433 Akhtar, Nosheen 598 Bae, Jong H. 660 Kennedy, William R. 247 Ko, Christine J. 119, 436 Al-Sadek, Camli 582 Baek, Yoosang 198 Keri, Jonette 291 Kobayashi, Tetsuro 508 Alberico, Stephanie 084 Baer, Janina 679 Kerkof, Keith 281 Koelle, David 015 Albuquerque, Celina 065 Baerenwald, Devin 138 Kern, Dale G. 265, 433 Koetsier, J 378 Alessi Cesar, Sabrina 250 Bagby, Stacey 624 Khalsa, Amrit S. 309 Kohwi-Shigematsu, Terumi 679 Alexeev, Vitali 652 Baghdadi, T 692 Khan, Neelam 056, 080 Koike, Saaya 700 Algazi, Alain 194 Bai, Jing 088 Khan, Sikandar G. 112 Kolbe, Ludger 604, 727 Ali, Niwa 675 Baida, Gleb 491 Khavari, Paul 145, 341, 391, 412, 418, 451 Komine, Mayumi 220, 374 Alijarde, Roberto 275 Bailey, Irene 174 Khidhir, Karzan 678 Komorowski, Lars 060 Alkelai, A 066 Bak, Soon-Sun 659 Khosravi-Maharlooei, Mohsen 673 Kong, Betty 480 Ally, Mina S. 132, 174, 315 Bakshi, Pooja 396 Khusial, Raaj P. 605, 663 Kong, Heidi H. 180, 240, 508 Almeida, Adam R. 648 Ballard, David H. 536 Khuu, Phuong 418 Konger, Raymond L. 590, 593 Alshehri, Wedad 173 Balooch, Guive 249 Kiatsurayanon, Chanisa 526 Königsrainer, Alfred 420 Alves, Paul 056 Banez, Lionel 251 Kibbi, Nour 031 Konnikov, Nellie 291 Alvim, Rafael 316, 317, 318 Banga, Ajay K. 063, 338, 362, 396 Kido, Tatsuo 622 Koon, Henry 292 Amagai, Masayuki 098, 352, 508 Bao, Xiaomin 451 Kiefer, Amy 244 Kopan, Raphael 021 Ambrose, Jeffery J. 536 Bar-Hen, Avner 269 Kiguradze, Tinatin 260 Kopecki, Zlatko 538 Amin, Ahmad S. 260 Baratti, Mariana 525 Killeen, Meghan 414 Koppel, Aaron 681 Amoh, Yasuyuki 691 Barcellos-Hoff, Mary Helen 580 Kim, Arianna 115, 150, 597 Korgavkar, Kavari 622 Anandasabapathy, Niroshana 003, 004, 007 Bardot, Evan 680 Kim, Brian S. 535 Korkmaz, Emrullah 550 Anderson, Abraham 281 Barkoukis, Hope 214 Kim, Caroline C. 643 Korman, Neil 214, 278, 424 Anderson, Mark S. 028 Barnes, Drew H. 552 Kim, Chang-Eop 601 Korolevich, Susanna 221 Anderson, Mary E. 511 Barnes, Kathleen 350 Kim, Dae H. 660 Koshiba, Takumi 361 Andl, Claudia D. 711, 735 Baron, Elma D. 584 Kim, Dae Suk 512 Koster, Maranke I. 641 Andl, Thomas 711, 735 Barthel, Steven R. 004 Kim, Dong Joo 190, 198 Kotol, Paul 193 Andre-Frei, Valerie 380, 485, 542 Barzegar, Mohammad R. 464, 466 Kim, Dongwon 365 Koval, Michael 351 Andrews, J. 259, 395, 705, 730, 733 Barzilai, A 066 Kim, Geurim 132 Kovalenkov, Yevgeniy 046 Angra, Divya 112 Basel-Vanagaite, Lina 457 Kim, Hee Joo 512 Kovalski, Joanna 412 Ansell, David 666 Bashir, Hasan 149 Kim, Hyun J. 660 Kowalczyk, Andrew 479, 704 Antaya, Richard 436 Bashir, Muhammad 056, 067 Kim, Jaehwan 190, 198, 228, 392 Koyama, Sachiko 477 Antes, Travis 130 Bashkirova, Elizaveta 428 Kim, Jenny 407, 531 Kraemer, Kenneth H. 112 Aplin, Andrew 107 Basiri, M R. 464 Kim, Jin-Chul 669 Kraft, Robert 187 Arave, Rowan 625 Bastien, Philippe 249 Kim, Jung-Chul 659 Krajenta, Richard 287 Arbieva, Zarema 567 Batazzi, Adriana 144 Kim, Kyu Han 483 Krakowski, Andrew 207 Arbiser, Jack L. 063, 176, 495 Baudouin, Caroline 197, 369 Kim, Min-Kyoung 481 Krämer, Ursula 286 Arcaroli, John J. 624 Bauer, Jürgen 136 Kim, Moon 659 Krausz, Aimee 239, 295 Archer, Nate 510 Baum, S 066 Kim, Noori 160, 231 Kricorian, Greg 281 S128 Journal of Investigative Dermatology (2015), Volume 135 S136 Journal of Investigative Dermatology (2015), Volume 135 108 AUTHOR INDEX AUTHOR INDEX

Arcioni, Marianne 356 Krieg,A Thomas 484 Lavrijsen, Sjan 343 Ardeleanu, Marius 169 Krieger,Aasi, Sumaira José E. Z. 316,209 317, 318 Lazar, Jozef 129 Krishnan,Abaci, Hasan Anuradha E. 658401, 427, 715 Lazarova,Arenas, ElsaZelmira 129,224, 223 230 Krol,Abbas, Yevgeniy Abul K. 603011, 016, 029, 034, 675 Le,Ariizumi, Lu Q. Kiyoshi 108096, 199 Kroshinsky,Abbas, Tazeen Daniela 171229 LeArmento, Poole, Caroline Alexander 047566, 725 Krueger,Abdel-Malek, James ZalfaG. A. 036,607 042, 049, 055, 082, 085, 165, 190, Lebeux,Armile, Celine James A. 542212 Abdelgawwad, Mohammad 192,582 198, 225, 255, 266, 280, 281, 392, Lebleu,Armstrong, Alexia April W. 354246, 303 Abdul-Wahab, Alya 394,411 445, 562, 686 LeBoeuf,Armstrong, Matthew Cheryl A. 668520 Krutmann,Abe, Riichiro Jean 286,361 288, 293, 375, 589 Lebonvallet,Arnold, Steven Nicolas E. 336310 Kubick,Abecasis, Bradley Goncalo J. 114438, 440 Lechler,Arozenius, Terry Helena 113,006 371 Kubo,Abels, Akiharu Christoph 352359 Leclere-Bienfait,Arron, Sarah Sophie 369102, 133, 384 Kubo,Abeni, Ryoji Damiano 216417 Lee,Artis, Alexander Keli 425193, 350 Kuhn,Achtman, Diane Jordan M. C. 160,073 231, 250 Lee,Artomov, Carolyn Mykyta 145134 Kulichová,Adachi, Akimasa Daniela 667220 Lee,Asada, Chih-Hung Hideo 103,054 523 Kumamoto,Adams, Peter Junichi D. 377156 Lee,Asano, Chun-Yue Yoshihide I. 185009, 177 Kumar,Adase, AnilChris 458337 Lee,Asgari, Da Maryam M. 509305 Kumar,Adhami, Raj Vaqar 636559 Lee,Ashbaugh, Dayae Alyssa 483509, 510 Kumar,Adhikary, Ranjit Gautam 582143, 389 Lee,Aspiroz, Delphine Carmen J. 201189 Kumar,Adler, BrandonSuresh 223239, 295, 531, 713 Lee,Astry, Dong Brian Hun 217,557 481 Kumar,Admani, Vinod Shehla 679219 Lee,Ata, Dong Mohammad Won O. 732581 Kuo,Adotama, Cheng-Chin Prince 437329 Lee,Atanasova, Ga-Young Velina 421426 Kuo,Afanasiev, Min-Liang Olga 109015 Lee,Athar, Hemin Mohammad 017,150, 252, 571, 556 651 Kupper,Afaq, Farrukh Thomas S. 017,571, 026, 638 039, 041, 043, 072, 082, 123, Lee,Atsugi, Ji Hyun Toru 022,352 540 Afshar, Maryam 147,207 225, 227, 262, 415, 421 Lee,Atwood, Ju Hee Scott 252,120, 732 132, 174 Kurniawan,Agak, George Jonas W. 249407, 531 Lee,Atzmony, Jun young Lihi 022457 Kurpad,Agarwal, Deepa Ashwin 721,164, 722 251 Lee,Aust, Jungsoo Samantha 017,083, 252, 084 556 Kutty,Agarwal, Lekha Priti 624013 Lee,Awgulewitsch, Kristina M. Alexander 443690 Kwasny,Aggarwal, Mary Rohit 158050 Lee,Ayehunie, Kwang H.Seyoum 017,566 085, 252, 556, 732 Kwiatkowski,Agón, Pedro Nicholas 636275 Lee,Ayithan, Min-Geol Natarajan 512544 Ahmad, Israr 581 Lee,Azambuja, Robert A. Ana P. 337316, 317, 318 Ahmad, Nihal 654 Lee,Aziz, Sandra Ahmar J. 643709 LAhmed, Rehana L. 612 Lee, Se-Rah 217, 481 labarrade,Ahn, Jaewoo Florian 627198 Lee, Seung Yun 251 Lachmann,Ahn, Richard Nadège 197443 Lee,B Sin Hee 515 Lafitte,Ahn, Sung Patrick K. 547660 Lee,Babineau, Vivian Denise 149350 Lagnese,Ahrns, Hadjh John S. 322298 Lee,Bacchiocchi, Wei-Li Antonella 344148, 606, 635 Lagovsky,Aiba, Setsuya Irina 457700 Lee,Bachelor, Wen-han Michael A. 715566, 647, 725 Lai,Akhtar, Gary Nosheen 717598 Lee,Bae, Wendy Jong H. 689660 Lai,Al-Sadek, Kevin Camli 409582 Lee,Baek, Won Yoosang Jai 732198 Lai,Alberico, Olivia Stephanie 490,084 712 Lee,Baer, Ye JaninaJin 022679 Lai,Albuquerque, Zhongbin Celina 044065 Lee,Baerenwald, Ying-Hsien Devin 513138 Laiho,Alessi LilyCesar, Sabrina 586250 Lee,Bagby, Yong-Moon Stacey 102624 Lais,Alexeev, Petra Vitali 364652 Lee,Baghdadi, Young S. T 273,692 296, 328 Lajevardi,Algazi, Alain Newsha 304194 Leftheris,Bai, Jing Katerina 367088 Lala,Ali, NiwaDeepak 367675 Legouffe,Baida, Gleb Raphael 376491 Lall,Alijarde, Rahul Roberto K. 598275 Lehigh,Bailey, Elisabeth Irene 433174 Lally,Alkelai, Aoife A 210066 Lehman,Bak, Soon-Sun Julia 243659 Lam,Ally, ChristinaMina S. 232132, 174, 315 Lehmann,Bakshi, Pooja Kim 221396 Lam,Almeida, Minh Adam R. 584648 Leigh,Ballard, Irene David H. 486536 Lambert,Alshehri, Sylviane Wedad 248173 Lenn,Balooch, Jon Guive 005249 LambertAlves, Paul de Rouvroit, Catherine 335056 Lens,Banez, Assuan Lionel 610251 Lan,Alvim, Cheng-Che Rafael 701316, 317, 318 Lentini,Banga, Tim Ajay K. 049063, 338, 362, 396 Lancet,Amagai, D Masayuki 066098, 352, 508 Leone,Bao, XiaominDominick 614451 Landriscina,Ambrose, Jeffery Angelo J. 531536 Leoty-Okombi,Bar-Hen, Avner Sabrina 485,269 542 Landry,Amin, Ahmad Tim S. 566260 Lerchner,Baratti, MarianaA 416525 Lane,Amoh, Majella Yasuyuki E. 372,691 569 Leslie,Barcellos-Hoff, Douglas S. Mary Helen 297580 Lane,Anandasabapathy, Alfred Niroshana 418003, 004, 007 Lesovaya,Bardot, Evan Ekaterina 491680 Langbein,Anderson, Lutz Abraham 388281 Leung,Barkoukis, Donald Hope 193,214 350 Leung, Sherry 160, 231, 599 Langenhan,Anderson, MarkJamie S. 596028 Barnes, Drew H. 552 Langer, Jessica 269 Leung, Thomas H. 418 Anderson, Mary E. 511 Barnes, Kathleen 350 Langerveld, Anna J. 433 Lev-Tov, Hadar 239, 295 Andl, Claudia D. 711, 735 Baron, Elma D. 584 Langhoff, Erik 294 Lever, R. 569 Andl, Thomas 711, 735 Barthel, Steven R. 004 Langridge, Timothy 101, 423 Levin, Lonny 146 Andre-Frei, Valerie 380, 485, 542 Barzegar, Mohammad R. 464, 466 Lanka, Lakshmana R. 176 Levine, Michael A. 422 Andrews, J. 259, 395, 705, 730, 733 Barzilai, A 066 Lanka, Padmavathy 176 Levinsohn, Jonathan 465 Angra, Divya 112 Basel-Vanagaite, Lina 457 Larcher, Fernando 151 Lew, Robert 291 Ansell, David 666 Bashir, Hasan 149 Lardone, Ricardo D. 201 Lewandowski, Katherine 413 Antaya, Richard 436 Bashir, Muhammad 056, 067 Larregina, Adriana T. 030, 541 Lewis, Christopher W. 196 Antes, Travis 130 Bashkirova, Elizaveta 428 Latif, Haythem 193 Lewis, Julia 125, 379 Aplin, Andrew 107 Basiri, M R. 464 Latkowski, Jo-Ann 237 Lewis, Steven M. 049 Arave, Rowan 625 Bastien, Philippe 249 Lau, Chris 622 Li, Angela 234 Arbieva, Zarema 567 Batazzi, Adriana 144 Laumann, Anne E. 260 Li, Bing 012, 023 Arbiser, Jack L. 063, 176, 495 Baudouin, Caroline 197, 369 Lauren, Christine 444 Li, Bingshan 440 Arcaroli, John J. 624 Lavertu, Pierre 292 Li,Bauer, Changzhao Jürgen 571136 Archer, Nate 510 Baum, S 066 www.jidonline.org S137 S128 Journal of Investigative Dermatology (2015), Volume 135 109 AUTHOR INDEX AUTHOR INDEX

Arcioni, Marianne 356 Li, Chenglong 027 Liu, Minglin 067 A Aasi, Sumaira Z. 209 Ardeleanu, Marius 169 Li, Chengxin 592 Liu, Qin 535 Abaci, Hasan E. 401, 427, 715 Arenas, Elsa 224, 230 Li, Chunying 075, 319, 456, 619, 645 Liu, Sucai 624 Abbas, Abul K. 011, 016, 029, 034, 675 Ariizumi, Kiyoshi 096, 199 Li, Hui 591, 650 Liu, Weimin 640 Abbas, Tazeen 229 Armento, Alexander 566, 725 Li, Jennifer C. 330 Liu, Xinjian 128 Abdel-Malek, Zalfa A. 607 Armile, James A. 212 Li, Jiang 120, 132 Liu, Xiping 517 Abdelgawwad, Mohammad 582 Armstrong, April W. 246, 303 Li, JiLon 149 Liu, Ying 687 Abdul-Wahab, Alya 411 Armstrong, Cheryl A. 520 Li, Kai 319 Liu, Yong 003, 004, 007 Abe, Riichiro 361 Arnold, Steven E. 310 Li, Li 141, 334, 708 Liu, Zhen 152 Abecasis, Goncalo 438, 440 Arozenius, Helena 006 Li, Lingjie 428 Liu, Zhi 091, 152, 382, 494 Abels, Christoph 359 Arron, Sarah 102, 133, 384 Li, Lingna 691 Livingstone, John 622 Abeni, Damiano 417 Artis, Keli 193, 350 Li, Luowei 153 Lloid, Michele 173 Achtman, Jordan C. 073 Artomov, Mykyta 134 Li, Mingli 047 Lloyd, Jenifer R. 212, 267 Adachi, Akimasa 220 Asada, Hideo 054 Li, Ning 091, 152, 382, 494 Lo, Chia-Hui 528 Adams, Peter D. 156 Asano, Yoshihide 009, 177 Li, Q. 259, 378, 395, 422, 462, 464, 466, 468, Lo, Yuan-Hsin 528 Adase, Chris 337 Asgari, Maryam M. 305 692, 730 Lockhart, Alexandre 193, 350 Adhami, Vaqar 559 Ashbaugh, Alyssa 509, 510 Li, Rui 244, 265 Lockshin, Benjamin 203 Adhikary, Gautam 143, 389 Aspiroz, Carmen 189 Li, Shaowei 168, 441 Loesch, Mathew 154 Adler, Brandon 239, 295, 531, 713 Astry, Brian 557 Li, Shufeng 234 Loesche, Michael 533 Admani, Shehla 219 Ata, Mohammad O. 581 Li, Shuli 456 Löfdahl, Anna 006 Adotama, Prince 329 Atanasova, Velina 426 Li, Tricia 325 Lofftus, Serena 043 Afanasiev, Olga 015 Athar, Mohammad 150, 571, 651 Li, Wei 053, 104, 345, 500, 729 Loh, Clement C. 228 Afaq, Farrukh 571, 638 Atsugi, Toru 352 Li, Wen-Qing 178, 299, 304, 311, 323, 324, 325 Londono, Douglas 118 Afshar, Maryam 207 Atwood, Scott 120, 132, 174 Li, Xiaoxue 643 Longley, Jack 598 Agak, George W. 407, 531 Atzmony, Lihi 457 Li, Xilong 186 Longmate, Whitney M. 706 Agarwal, Ashwin 164, 251 Aust, Samantha 083, 084 Li, Yong 467 Lopez de Padilla, Consuelo 050 Agarwal, Priti 013 Awgulewitsch, Alexander 690 Li, Yumeng 033, 037 Lopez-Pajares, Vanessa 391 Aggarwal, Rohit 050 Ayehunie, Seyoum 566 Li, Yunmin 622 Lorencini, Marcio 363 Agón, Pedro 275 Ayithan, Natarajan 544 Li, Zhiwen 293 Lorenz, H P. 418 Ahmad, Israr 581 Azambuja, Ana P. 316, 317, 318 Liang, Bruce T. 442 Lorinda, Chung 064 Ahmad, Nihal 654 Aziz, Ahmar 709 Liang, Christine 182 Loring, Erin 444 Ahmed, Rehana L. 612 Liao, Chung-Ping 108 Lotesta, Stephen 367 Ahn, Jaewoo 198 Liao, Wilson 095, 431, 443 Lott, Jason P. 333 Ahn, Richard 443 Liaw, Eric 428 Lotto, Christine F. 497, 730 B Ahn, Sung K. 660 Babineau, Denise 350 Libove, Eileen 116 Loutit, Kylie 418 Ahrns, Hadjh S. 298 Bacchiocchi, Antonella 148, 606, 635 Lichtman, Michael 232, 731 Low, Benjamin E. 435 Aiba, Setsuya 700 Bachelor, Michael A. 566, 647, 725 Lifton, Richard 444 Low, Hui QI 431 Akhtar, Nosheen 598 Bae, Jong H. 660 Lifton, Richard P. 436 Lowe, Margaret 095 Al-Sadek, Camli 582 Baek, Yoosang 198 Lilly, Evelyn 200 Lowes, Michelle 049, 190, 198 Alberico, Stephanie 084 Baer, Janina 679 Lim, Henry W. 287, 582 Lowry, Elizabeth 072, 082, 225, 415, 421 Albuquerque, Celina 065 Baerenwald, Devin 138 Lim, Young H. 436 Lu, Chuanjian 093 Alessi Cesar, Sabrina 250 Bagby, Stacey 624 Lin, Andrew 187 Lu, Kurt Q. 726 Alexeev, Vitali 652 Baghdadi, T 692 Lin, Athena 249 Lu, Meng-Ping 528 Algazi, Alain 194 Bai, Jing 088 Lin, Charles 041 Lu, Ming 498 Ali, Niwa 675 Baida, Gleb 491 Lin, Chenyan 060 Lu, Yan 648 Alijarde, Roberto 275 Bailey, Irene 174 Lin, Congxing 681 Lucena, Silvia 151 Alkelai, A 066 Bak, Soon-Sun 659 Lin, Fubao 710 Luiten, Rosalie 047 Ally, Mina S. 132, 174, 315 Bakshi, Pooja 396 Lin, Hsien-Yi 437 Luna, Sara A. 194 Almeida, Adam R. 648 Ballard, David H. 536 Lin, Jiayuh 027 Luo, Yuchun 106, 624, 640, 648 Alshehri, Wedad 173 Balooch, Guive 249 Lin, Kevin 194, 409 Luria, Victor 720 Alves, Paul 056 Banez, Lionel 251 Lin, Lin 152, 494 Lwin, Su M. 411 Alvim, Rafael 316, 317, 318 Banga, Ajay K. 063, 338, 362, 396 Lin, Pei-Husan 437 Lyga, John 385, 605, 663, 697 Amagai, Masayuki 098, 352, 508 Bao, Xiaomin 451 Lin, Samantha 662 Lyles, James 545 Ambrose, Jeffery J. 536 Bar-Hen, Avner 269 Lin, Steven 246 Lyons, Scott P. 706 Amin, Ahmad S. 260 Baratti, Mariana 525 Lin, Sung-Jan 670, 671, 676 Lyssiotis, Costas 146 Amoh, Yasuyuki 691 Barcellos-Hoff, Mary Helen 580 Lin, Xiaofeng 631, 724, 728, 731 Anandasabapathy, Niroshana 003, 004, 007 Bardot, Evan 680 Lin, Zhimiao 456 Anderson, Abraham 281 Barkoukis, Hope 214 Lipinski, Kerri K. 367 M Anderson, Mark S. 028 Barnes, Drew H. 552 Lish, Samantha 049 Ma, Averil 443 Anderson, Mary E. 511 Barnes, Kathleen 350 Lissin, Dmitri 406 Ma, Cuiling 456 Andl, Claudia D. 711, 735 Baron, Elma D. 584 Litman, Thomas 394 Ma, Dinglong 170 Andl, Thomas 711, 735 Barthel, Steven R. 004 Liu, Aimin 141 Ma, Liang 681 Andre-Frei, Valerie 380, 485, 542 Barzegar, Mohammad R. 464, 466 Liu, Chengbao 141 Macarak, Edward 497, 705 Andrews, J. 259, 395, 705, 730, 733 Barzilai, A 066 Liu, Chiachi 108 Maccario, Frederic 547 Angra, Divya 112 Basel-Vanagaite, Lina 457 Liu, Fang 668, 691 Mack, Madison R. 535 Ansell, David 666 Bashir, Hasan 149 Liu, Fu-Tong 246, 528 Mackay-Wiggan, Julian 019, 079, 238, 264, 272 Antaya, Richard 436 Bashir, Muhammad 056, 067 Liu, Guodong S. 296, 309 Mackelfresh, Jamie 176 Antes, Travis 130 Bashkirova, Elizaveta 428 Liu, Ji-Bin 722 MacLeod, Amanda S. 040 Aplin, Andrew 107 Basiri, M R. 464 Liu, Jianjun 431, 443 Maghami, Siaavash 707 Arave, Rowan 625 Bastien, Philippe 249 Liu, Kristina 222 Magin, Thomas 679 Arbieva, Zarema 567 Batazzi, Adriana 144 Liu, Liang 597 Mah, Angela 145 Arbiser, Jack L. 063, 176, 495 Baudouin, Caroline 197, 369 Liu, Lin 645 Mahalingam, Meera 614 Arcaroli, John J. 624 Bauer, Jürgen 136 Liu, Ling 075, 319 Mahoney, My G. 502, 721 Archer, Nate 510 Baum, S 066 Liu, Ming 169 Maidhof, Robert 697 S128 Journal of Investigative Dermatology (2015), Volume 135 S138 Journal of Investigative Dermatology (2015), Volume 135 110 AUTHOR INDEX AUTHOR INDEX

Arcioni, Marianne 356 Mak,A Yvonne 507 McNeely, Tessie B. 548 Aasi, Sumaira Z. 209 Ardeleanu, Marius 169 Maki, Nobuki 220 McNiff, Jennifer 436, 465 Arenas, Elsa 224, 230 Malajian,Abaci, Hasan Dana E. 036,401, 165, 427, 562 715 Means, Alex 306 Malashchuk,Abbas, Abul Igor K. 679011, 016, 029, 034, 675 Medamana,Ariizumi, KiyoshiJohn 710096, 199 Malchin,Abbas, Tazeen N 378,229 450 Medler,Armento, Terry Alexander R. 127566, 725 Malyrchuk,Abdel-Malek, Viktor Zalfa A. 249607 Mehrotra,Armile, JamesShikhar A. 047212 Mamalis,Abdelgawwad, Andrew Mohammad 577582 Mehta,Armstrong, Nehal AprilN. W. 203,246, 219 303 Man,Abdul-Wahab, George Alya 348,411 360 Mei,Armstrong, Bing C. Cheryl A. 385520 Man,Abe, Mao-Qiang Riichiro 348,361 360, 400 Meisel,Arnold, Jacquelyn Steven E. 553,310 554 Manco,Abecasis, Megan Goncalo 249438, 440 Mellerio,Arozenius, Jemima Helena 411006 Mangelberger,Abels, Christoph Doris 124359 Melo,Arron, Sandra Sarah 428102, 133, 384 Manivasagam,Abeni, Damiano Sindhu 021417 Meloni,Artis, KeliMarisa 718193, 350 Manley,Achtman, MIchael Jordan C. 210073 Meng,Artomov, Shi Mykyta 367134 Mano,Adachi, Camila Akimasa 606,220 635 Merghoub,Asada, Hideo Taha 146054 Manser,Adams, Timothy Peter D. 094156 Merideth,Asano, Yoshihide Melissa 112009, 177 Manson,Adase, Chris JoAnn E. 315337 Mesinkovska,Asgari, Maryam Natasha M. 665305 Mansouri,Adhami, VaqarP 464559 Messenger,Ashbaugh, Gregory Alyssa 229509, 510 Mansouri,Adhikary, Yasaman Gautam 686143, 389 Messersmith,Aspiroz, Carmen Wells 624189 Mantel,Adler, BrandonAlon 684239, 295, 531, 713 Messina,Astry, Brian Catherine 315557 Mao,Admani, Xuming Shehla 059219 Messingham,Ata, Mohammad Kelly O. 083,581 084 Mao,Adotama, Yujie Prince 708329 Metzger,Atanasova, D Velina 155426 Marcu,Afanasiev, Laura Olga 170015 Metzger,Athar, MohammadTodd C. 028150, 571, 651 Marcus,Afaq, Farrukh Andrew 367571, 638 Metzger,Atsugi, YCToru 450352 Mardaryev,Afshar, Maryam Andrei 679,207 709 Meyer,Atwood, Colin Scott J. 185120, 132, 174 Marfatia,Agak, George Twinkal W. 452407, 531 Meyer,Atzmony, Melissa Lihi 021457 Margolis,Agarwal, David Ashwin J. 533164, 251 Mi,Aust, Qing-Sheng Samantha 093083, 084 Marinaro,Agarwal, XavierPriti 261013 Miccio,Awgulewitsch, Joseph A. Alexander 261690 Marinkovich,Aggarwal, Rohit M. Peter 412,050 418 Micevic,Ayehunie, Goran Seyoum 634566 Marito,Agón, PedroShinta 539275 Michaels,Ayithan, Kellie Natarajan A. 495544 Markioli,Ahmad, Pierre-GillesIsrar 547581 Michalowski,Azambuja, AnaAleksandra P. 153316, 317, 318 Markovics,Ahmad, Nihal Adrienn 567654 Michalski,Aziz, Ahmar Basia M. 129709 Marshall,Ahmed, RehanaC L. 149,612 157, 416 Mieremet, Arnout 342 Martin,Ahn, Jaewoo Jo 599198 Migliano, Emilia 719 Martinez,Ahn, Richard Anna 411443 Mii,B Sumiyuki 691 Martinez,Ahn, Sung Camilo K. 230660 Milam,Babineau, Emily Denise C. 051350 Martinez-Quiepo,Ahrns, Hadjh S. Magdalena 411298 Millar,Bacchiocchi, Sarah Antonella 668,148, 685 606, 635 Martínez-Rosales,Aiba, Setsuya Karla I. 268,700 615 Miller,Bachelor, David Michael M. A. 636566, 647, 725 Martinka,Akhtar, Nosheen Magdalena 449598 Miller,Bae, JongJeffrey H. J. 297660 Martires,Al-Sadek, Kathryn Camli J. 237,582 211 Miller,Baek, Lloyd Yoosang S. 509,198 510 Marttala,Alberico, Jaana Stephanie 705,084 733 Miller,Baer, Natalie Janina 015679 Marty,Albuquerque, Timour Celina 281065 Millerman,Baerenwald, Beth Devin 505138 Marzuka,Alessi Cesar, Alexander Sabrina 632250 Mills,Bagby, David Stacey K. 536624 Masashi,Alexeev, Miyai Vitali 368652 Milone,Baghdadi, Michael T C. 059692 Masuda,Algazi, AlainHideyuki 575194 Milora,Bai, Jing Katelynn A. 514088 Mathelier,Ali, Niwa Anthony 734675 Milstone,Baida, Gleb Leonard 458491 Mathers,Alijarde, Alicia Roberto R. 414,275 550 Ming,Bailey, Mei Irene 107,174 347 Mathias,Alkelai, RasikaA 350066 Minot,Bak, Soon-SunSamuel 553659 Mathur,Ally, Mina Anubhav S. N. 034132, 174, 315 Mirkin,Bakshi, Chad Pooja 373,396 413 Matos,Almeida, Tiago Adam R. R. 026,648 072, 082, 415 Mirza,Ballard, Haris David H. 458536 Matsui,Alshehri, Mary Wedad S. 288,173 293, 602 Misery,Balooch, Laurent Guive 336249 Matsumoto,Alves, Paul Yuuko 368056 Missaghi,Banez, LionelMelody 173251 Matsushita,Alvim, Rafael Natsuki 472316, 317, 318 Mitchell,Banga, BrendonAjay K. 614063, 338, 362, 396 Mattheyses,Amagai, Masayuki Alexa 479098, 352, 508 Mitchell,Bao, Xiaomin Hunter 370451 Matts,Ambrose, P. J. Jeffery J. 569536 Miyachi,Bar-Hen, Yoshiki Avner 206269 Mauro,Amin, MichaelAhmad S. 257260 Miyagaki,Baratti, MarianaTomomitsu 009,525 177, 188 Mauro,Amoh, Theodora Yasuyuki 102,691 351, 381 Miyagawa,Barcellos-Hoff, Fumi Mary Helen 054580 Maxson,Anandasabapathy, Robert Niroshana 717003, 004, 007 Mlitz,Bardot, Veronika Evan 390680 Maxwell,Anderson, Melissa Abraham 487,281 642 Mochizuki,Barkoukis, Hideki Hope 187214 Mazori,Anderson, Daniel Mark R. S. 242,028 279, 290 Mockler,Barnes, DanielDrew H. 649552 McArdle,Anderson, Susan Mary E. 256511 Modlin,Barnes, Robert Kathleen 572,350 574 McBride,Andl, Claudia Jeffrey D. D. 087711, 735 Mohammed,Baron, Elma Javed D. 557584 McCavana,Andl, Thomas Jackie 210711, 735 Mollah,Barthel, Shamim Steven R. 003004 McClain,Andre-Frei, Steven Valerie 261380, 485, 542 Moncada,Barzegar, Benjamin Mohammad R. 224,464, 230, 466 268 McCormick,Andrews, J. Thomas 033,259, 037, 395, 214, 705, 278, 730, 501, 733 530, 561 Moncayo,Barzilai, AlejandraA 649066 McCoy,Angra, DivyaJohn 672112 Montes-Camacho,Basel-Vanagaite, MayraLina 655457 McCray,Ansell, DavidChristina 040666 Moon,Bashir, James Hasan J. 011149 McElwee,Antaya, Richard Kevin J. 673436 Moon,Bashir, Seong-Joon Muhammad 600056, 067 McGeehan,Antes, Travis Gerard M. 367130 Moon,Bashkirova, Youbin Elizaveta 621428 McGirt,Aplin, AndrewLaura Y. 138107 Moore,Basiri, John M R. 506464 McGrath,Arave, Rowan John 408,625 411, 486 Moore,Bastien, Richard Philippe 617249 McGuinn,Arbieva, ZaremaKathleen P. 502567 Mora,Batazzi, Ariana Adriana 182144 McLean,Arbiser, IrwinJack L. 450,063, 486 176, 495 Morasso,Baudouin, Maria Caroline 097,197, 669 369 McManus,Arcaroli, John Hamish J. 228624 Morehouse,Bauer, Jürgen Chris 221136 McMillan,Archer, Nate James 486510 Morel,Baum, Kimberly S 444066

S128 Journal of Investigative Dermatology (2015), Volume 135 www.jidonline.org S139 111 AUTHOR INDEX AUTHOR INDEX

Arcioni, Marianne 356 Morelli, Adrian 030, 541 Nemeth, Valerie N. 048 A Aasi, Sumaira Z. 209 Ardeleanu, Marius 169 Morgan, Bruce 696 Nesterovitch, Andrew 567 Abaci, Hasan E. 401, 427, 715 Arenas, Elsa 224, 230 Morimura, Sohshi 009 Neuburg, Marcy 129 Abbas, Abul K. 011, 016, 029, 034, 675 Ariizumi, Kiyoshi 096, 199 Morita, Akimichi 208, 216, 293, 575 Neufang, Gitta 604, 727 Abbas, Tazeen 229 Armento, Alexander 566, 725 Morizane, Shin 551 Neumann, Claudia 359 Abdel-Malek, Zalfa A. 607 Armile, James A. 212 Morris, Rebecca J. 118 Neves da Silva, Marlene 525, 563 Abdelgawwad, Mohammad 582 Armstrong, April W. 246, 303 Morrisey, Edward 685 Newman, Jessica 294 Abdul-Wahab, Alya 411 Armstrong, Cheryl A. 520 Morrow, Casey D. 582 Newton, Victoria 387 Abe, Riichiro 361 Arnold, Steven E. 310 Moser, Catherine D. 658 Ng, Qimin 203 Abecasis, Goncalo 438, 440 Arozenius, Helena 006 Moshiri, Ata S. 256 Nghiem, Paul 015, 196, 256 Abels, Christoph 359 Arron, Sarah 102, 133, 384 Moslehi, Homayoun 133, 613 Nguyen, Catherine M. 095 Abeni, Damiano 417 Artis, Keli 193, 350 Moss, Joel 168, 441 Nguyen, Christie 145 Achtman, Jordan C. 073 Artomov, Mykyta 134 Mostaghimi, Arash 171 Nguyen, Harrison 503 Adachi, Akimasa 220 Asada, Hideo 054 Moy, Adrian 409 Nguyen, Hiep X. 338 Adams, Peter D. 156 Asano, Yoshihide 009, 177 Mozaffari, Nikoo 466 Nguyen, Ngon T. 412, 418 Adase, Chris 337 Asgari, Maryam M. 305 Muakkassa, Fuad 278 Nguyen, Nhan M. 238, 272 Adhami, Vaqar 559 Ashbaugh, Alyssa 509, 510 Mukherjee, Eric M. 071 Nguyen, Nicholas 624 Adhikary, Gautam 143, 389 Aspiroz, Carmen 189 Mukherjee, Nabanita 648 Nguyen, T 110 Adler, Brandon 239, 295, 531, 713 Astry, Brian 557 Mukherjee, Pranab K. 215 Ni, Xiao 101, 423 Admani, Shehla 219 Ata, Mohammad O. 581 Mukhtar, Hasan 559, 598 Nice, Timothy 038 Adotama, Prince 329 Atanasova, Velina 426 Munday, Michael 372 Nicolay, Jean-François 547 Afanasiev, Olga 015 Athar, Mohammad 150, 571, 651 Mur, Ludivine 627 Nie, Qing 693, 695 Afaq, Farrukh 571, 638 Atsugi, Toru 352 Murakami, Masamoto 472 Nielsen-Scott, Anna 102 Afshar, Maryam 207 Atwood, Scott 120, 132, 174 Muramatsu, Shinnosuke 208, 216 Nieves, Ashley 365 Agak, George W. 407, 531 Atzmony, Lihi 457 Murata, Satoru 220 Nihal, Minakshi 654 Agarwal, Ashwin 164, 251 Aust, Samantha 083, 084 Murphy, William 074, 577 Nikbakht, Neda 094 Agarwal, Priti 013 Awgulewitsch, Alexander 690 Murray, Stephen A. 661 Nilsson, Ulrika 549 Aggarwal, Rohit 050 Ayehunie, Seyoum 566 Murrell, Dedee F. 228 Ning, Weihuang 490 Agón, Pedro 275 Ayithan, Natarajan 544 Muthusamy, Viswanathan 634 Nirschl, Christopher 003, 004, 007 Ahmad, Israr 581 Azambuja, Ana P. 316, 317, 318 Muto, Jun 337, 702 Nirula, Ajay 281 Ahmad, Nihal 654 Aziz, Ahmar 709 Muzaffar, Anum 582 Nishida, Emi 208, 216 Ahmed, Rehana L. 612 Myung, Peggy 674 Nishigori, Chikako 621 Ahn, Jaewoo 198 Nishimura, Michael 047 Ahn, Richard 443 Nissinen, Liisa 100 B Ahn, Sung K. 660 Babineau, Denise 350 Nititham, Joanne 443 N Ahrns, Hadjh S. 298 Bacchiocchi, Antonella 148, 606, 635 Nacharaju, Parimala 713 Nittynen, juha 249 Aiba, Setsuya 700 Bachelor, Michael A. 566, 647, 725 Nadella, Prannay 392 Niu, Zhaoyang 570 Akhtar, Nosheen 598 Bae, Jong H. 660 Nagao, Keisuke 508 Niyonsaba, Francois 519, 526 Al-Sadek, Camli 582 Baek, Yoosang 198 Nagato, Gaku 669 Njauw, Jenny C. 616 Alberico, Stephanie 084 Baer, Janina 679 Nagayama, Masaharu 377 Noda, Shinji 036, 085, 165, 280, 394, 686 Albuquerque, Celina 065 Baerenwald, Devin 138 Nagelreiter, Ionela M. 594 Noh, Ji Yeon 017, 252, 556, 732 Alessi Cesar, Sabrina 250 Bagby, Stacey 624 Naik, Haley B. 203 Nomura, Toshifumi 432 Alexeev, Vitali 652 Baghdadi, T 692 Nair, Rajan P. 248, 263, 438, 440 Norris, David 019, 079, 141, 264, 624, 640, 641, 648 Algazi, Alain 194 Bai, Jing 088 Najor, N 378 North, Jeffrey 384 Ali, Niwa 675 Baida, Gleb 491 Nakachi, Ichiro 106 Nosanchuk, Joshua 531 Alijarde, Roberto 275 Bailey, Irene 174 Nakajima, Saeko 206, 394 Nosbaum, Audrey 011, 016 Alkelai, A 066 Bak, Soon-Sun 659 Nakamura, Mary S. 316, 317, 318 Nosgorodsky, J 066 Ally, Mina S. 132, 174, 315 Bakshi, Pooja 396 Nakatani, Masashi 597 Nosrati, Adi 622 Almeida, Adam R. 648 Ballard, David H. 536 Nakatsuji, Teruaki 193 Noto, Paul B. 367 Alshehri, Wedad 173 Balooch, Guive 249 Nam, Jin-Ju 600 Nouri, Keyvan 610 Alves, Paul 056 Banez, Lionel 251 Nambudiri, Vinod E. 242 Nowak, Ronald S. 495 Alvim, Rafael 316, 317, 318 Banga, Ajay K. 063, 338, 362, 396 Namkoong, Jin 433 Nuechel, Julian 484 Amagai, Masayuki 098, 352, 508 Bao, Xiaomin 451 Nanes, Benjamin A. 704 Nunez-Cruz, Selene 059 Ambrose, Jeffery J. 536 Bar-Hen, Avner 269 Narayan, Deepak 436 Nyugen, Don X. 119 Amin, Ahmad S. 260 Baratti, Mariana 525 Narayan, Suguna 373 Amoh, Yasuyuki 691 Barcellos-Hoff, Mary Helen 580 Narayanan, Nandakumar 084 Anandasabapathy, Niroshana 003, 004, 007 Bardot, Evan 680 Nardin, Charlée A. 146, 148 O Anderson, Abraham 281 Barkoukis, Hope 214 Nardone, Beatrice 260 O’Brien, Kathryn 500, 729 Anderson, Mark S. 028 Barnes, Drew H. 552 Narzt, Marie S. 594 O’Curran, Cassandra 662 Anderson, Mary E. 511 Barnes, Kathleen 350 Naseer, Sahar Y. 070 O’Donnell, James K. 278 Andl, Claudia D. 711, 735 Baron, Elma D. 584 Nasir, Wasim 229 O’Gorman, Susan M. 210 Andl, Thomas 711, 735 Barthel, Steven R. 004 Nasti, Tahseen H. 651 O’Malley, John T. 082 Andre-Frei, Valerie 380, 485, 542 Barzegar, Mohammad R. 464, 466 Natale, Christopher 156, 637 Oberto, Gilles 354, 627 Andrews, J. 259, 395, 705, 730, 733 Barzilai, A 066 Natarajan, Balaji 203, 219 Oda, Yuko 699 Angra, Divya 112 Basel-Vanagaite, Lina 457 Nathan, Neera 168 Oddis, Chester V. 050 Ansell, David 666 Bashir, Hasan 149 Nattkemper, Leigh A. 187 Oetjen, Landon K. 535 Antaya, Richard 436 Bashir, Muhammad 056, 067 Naughton, Gail 655 Offutt, Carlos 477 Antes, Travis 130 Bashkirova, Elizaveta 428 Naugler, Scott 258 Ofuya, Mercy 411 Aplin, Andrew 107 Basiri, M R. 464 Navati, Mahantesh 713 Ogawa, Hideoki 340, 519, 526 Arave, Rowan 625 Bastien, Philippe 249 Nazzal, Ehab 124 Ogawa, Youichi 669 Arbieva, Zarema 567 Batazzi, Adriana 144 Neary, Bridget 061 Ogdie, Alexis 289, 302 Arbiser, Jack L. 063, 176, 495 Baudouin, Caroline 197, 369 Nedorost, Susan 215 Ogurtsova, Aleksandra 599 Arcaroli, John J. 624 Bauer, Jürgen 136 Neil, Jessica 005, 505 Oh, Byungho 131 Archer, Nate 510 Baum, S 066 Nelson, Kate 545 Oh, Chee Won 179 S128 Journal of Investigative Dermatology (2015), Volume 135 S140 Journal of Investigative Dermatology (2015), Volume 135 112 AUTHOR INDEX AUTHOR INDEX

Arcioni, Marianne 356 Oh,A Chil-Hwan 198 Park, Joo-Eun S. 346 Ardeleanu, Marius 169 Oh,Aasi, Dennis Sumaira H. Z. 611209 Park, June J. 480 Oh,Abaci, In-kyung Hasan E. 601401, 427, 715 Park,Arenas, Kyungho Elsa 102,224, 381 230 Oh,Abbas, Jang-Hee Abul K. 217,011, 481, 016, 482, 029, 483 034, 675 Park,Ariizumi, Michelle Kiyoshi 148096, 199 Oh,Abbas, Ji Won Tazeen 693,229 695 Park,Armento, Moonhee Alexander 382566, 725 Oh,Abdel-Malek, Seung Mi Zalfa A. 365607 Park,Armile, Sang James Min A. 299212 Ohba,Abdelgawwad, Yusuke Mohammad 361582 Park,Armstrong, Sophia L.April W. 565,246, 650 303 Ohta,Abdul-Wahab, Shoichiro Alya 098411 Park,Armstrong, Yeun-Hee Cheryl A. 294520 Ohtsuka,Abe, Riichiro Tsutomu 163361 Park,Arnold, Yoonkyung Steven E. 520310 Ohtsuki,Abecasis, Mamitaro Goncalo 220,438, 374 440 Park,Arozenius, Young MinHelena 022,006 540 Oka,Abels, Masahiro Christoph 621359 Parlet,Arron, Corey Sarah 545102, 133, 384 Oka,Abeni, Tomonori Damiano 009,417 177, 188 Parsa,Artis, Ramine Keli 499193, 350 Okada,Achtman, Taro Jordan C. 621073 Pascoe,Artomov, Vanessa Mykyta 233134 Okawa,Adachi, JoyceAkimasa 056,220 073, 202, 596 Pastushenko,Asada, Hideo Ievgenia 583054 Okon,Adams, Lauren Peter G.D. 056156 Patel,Asano, Amish Yoshihide J. 108009, 177 Okumura,Adase, Chris Ko 526337 Patel,Asgari, Anisha Maryam M. 257305 Olafsson,Adhami, VaqarJohn H. 175559 Patel,Ashbaugh, Mital Alyssa 242,509, 279 510 Olala,Adhikary, Lawrence Gautam 403143, 389 Patel,Aspiroz, Neha Carmen 308189 Olasz,Adler, EditBrandon B. 129,239, 223 295, 531, 713 Patel,Astry, Shivani Brian 300557 Olazagasti,Admani, Shehla Jeannette M. 050,219 658 Pauli,Ata, MarielaMohammad L. O. 011,581 016, 029 Oldach,Adotama, Jonathan Prince 725329 Paulos,Atanasova, Cheryl Velina 047426 Olender,Afanasiev, T Olga 066015 Paulson,Athar, MohammadKelly G. 196150, 571, 651 Olowoyeye,Afaq, Farrukh Omolara 231571, 638 Paus,Atsugi, Ralf Toru 666352 Olson,Afshar, Eric Maryam 668207 Pawlikowski,Atwood, Scott Jeffery 156120, 132, 174 OMalley,Agak, George John W.T. 147,407, 225 531 Payne,Atzmony, Aimee Lihi S. 018,457 059, 071, 202 Ona-Vu,Agarwal, Katherine Ashwin 611164, 251 Peacock,Aust, Samantha Janet L. 411083, 084 Ong,Agarwal, Peck Priti 350013 Pelegati,Awgulewitsch, Vitor Alexander 525,690 563 Ong,Aggarwal, SuFey Rohit 144050 Pelle,Ayehunie, Edward Seyoum 393566 Orchard,Agón, Pedro David 228275 Peng,Ayithan, Tien Natarajan 685544 Oresajo,Ahmad, ChristianIsrar 603581 Pentland,Azambuja, Alice Ana P. P. 684316, 317, 318 Oro,Ahmad, Anthony Nihal 120,654 132, 135, 174, 428 Perdigoto,Aziz, Ahmar Carolina 680709 Ortines,Ahmed, RogerRehana L. 510612 Peredo, Carlos E. 005, 505 Ortiz-Urda,Ahn, Jaewoo Susana 194,198 409, 613 Pereira, Alexandre D. 316, 317, 318 Osborn,Ahn, Richard Mark J. 408443 Perez,B Eduardo 529, 568 Oses-Prieto,Ahn, Sung K. Juan 613660 PerezBabineau, White, Denise Bethany E. 473,350 723 Otero-Vinas,Ahrns, Hadjh Marta S. 724,298 728 Perez-Nazario,Bacchiocchi, NelissaAntonella 213148, 606, 635 Otto,Aiba, Michael Setsuya 011700 Pernodet,Bachelor, Nadine Michael A. 393,566, 630 647, 725 Ouyang,Akhtar, Nosheen Hao 623598 Peterson,Bae, Jong Shelby H. C. 111660 Ovits,Al-Sadek, Channa Camli G. 698582 Petit,Baek, Vanessa Yoosang A. 657198 Owen,Alberico, Joshua Stephanie L. 447084 Petrof,Baer, GabrielaJanina 411679 Oyoshi,Albuquerque, Michiko Celina 510065 Pettersson,Baerenwald, Lars Devin 006138 Ozdoganlar,Alessi Cesar, Burak Sabrina 550250 Petukhova,Bagby, Stacey Lynn 448,624 461 Alexeev, Vitali 652 Pham,Baghdadi, Hanh T 253,692 386 Algazi, Alain 194 Photenhauer,Bai, Jing A 155088 PAli, Niwa 675 Picardo,Baida, GlebMauro 719491 Page,Alijarde, Carly Roberto 509,275 510 Pichard,Bailey, DominiqueIrene 240174 Paglia,Alkelai, Melissa A 402066 Picksley,Bak, Soon-Sun Steve 678659 Pagoto,Ally, Mina Sherry S. 315132, 174, 315 Pielak,Bakshi, Rafal Pooja 249396 Pahl,Almeida, Jana Adam R. 140648 Pietkiewicz,Ballard, David Pawel H. 285536 Pais,Alshehri, K Wedad 155173 Pietroni,Balooch, Valentina Guive 097249 Pal,Alves, Harish Paul C. 638056 Pinney,Banez, Emmett Lionel 655251 Palak,Alvim, Shah Rafael 347316, 317, 318 Pires,Banga, Thiago Ajay F. K. 316,063, 317, 338, 318 362, 396 Palazzo,Amagai, ElisabettaMasayuki 097098, 352, 508 Pirozzi,Bao, Xiaomin Gianluca 169451 Paller,Ambrose, Amy Jeffery S. J. 036,536 165, 350, 373, 413, 444, 480, 644 Plaisier,Bar-Hen, Seema Avner B. 201269 Palmer,Amin, Ahmad Brian C. S. 024260 Planell-Mendez,Baratti, Mariana Ivette 209525 Palmeri,Amoh, Yasuyuki Mark 251691 Platanias,Barcellos-Hoff, Leonidas Mary Helen 491580 Palmqvist,Anandasabapathy, Niklas Niroshana 006003, 004, 007 Playford,Bardot, MartinEvan 203,680 219 Pamelard,Anderson, Fabien Abraham 376281 Plaza,Barkoukis, Christelle Hope 355,214 356, 357, 358 Plikus, Maksim 522, 693, 695 Pan,Anderson, Szu-Hua Mark S. 671028 Barnes, Drew H. 552 Pan, Youdong 043 Plomann, Markus 484 Anderson, Mary E. 511 Barnes, Kathleen 350 Pandarinathan, Lakshmipathi 487, 642 Pohle-Krauza, Rachael J. 267 Andl, Claudia D. 711, 735 Baron, Elma D. 584 Pandya, Amit 276 Poligone, Brian 008 Andl, Thomas 711, 735 Barthel, Steven R. 004 Panoutsopoulou, Ioanna G. 247 Pollack, Brian P. 045 Andre-Frei, Valerie 380, 485, 542 Barzegar, Mohammad R. 464, 466 Papoiu, Alexandru D. 187 Pollet, Marius 589 Andrews, J. 259, 395, 705, 730, 733 Barzilai, A 066 Pappas-Taffer, Lisa 202 Polley, Eric C. 180 Angra, Divya 112 Basel-Vanagaite, Lina 457 Paradisi, Andrea 417 Poloso, Neil J. 656, 678 Ansell, David 666 Bashir, Hasan 149 Pardos, Carlos 275 Pomerantz, Hyemin 195, 291, 307 Antaya, Richard 436 Bashir, Muhammad 056, 067 Parikh, Shruti 261 Ponda, Manish 190 Antes, Travis 130 Bashkirova, Elizaveta 428 Parisi, Nicola 372, 569 Ponnamperuma, Roshini M. 142 Aplin, Andrew 107 Basiri, M R. 464 Park, Bu M. 660 Ponzo, Marisa Grace G. 449 Arave, Rowan 625 Bastien, Philippe 249 Park, Chang Ook 017, 041, 043, 147, 252, 556, 732 Poon, Flora 160, 231 Arbieva, Zarema 567 Batazzi, Adriana 144 Park, Chi-Hyun 482 Popkin, Daniel 558 Arbiser, Jack L. 063, 176, 495 Baudouin, Caroline 197, 369 Park, Heuijoon 118 Poppas, Dix P. 698 Arcaroli, John J. 624 Park, Ji-Eun 600 Posch,Bauer, Christian Jürgen 123,136 409, 613, 655 Archer, Nate 510 Baum, S 066 www.jidonline.org S141 S128 Journal of Investigative Dermatology (2015), Volume 135 113 AUTHOR INDEX AUTHOR INDEX

Arcioni, Marianne 356 Posligua, Alba 260 Ranki, Annamari 458 A Aasi, Sumaira Z. 209 Ardeleanu, Marius 169 Postlethwaite, Arnold E. 345 Ransohoff, Julia 391 Abaci, Hasan E. 401, 427, 715 Arenas, Elsa 224, 230 Poterlowicz, Krzysztof 679, 709 Ransohoff, Katherine J. 174, 209, 315 Abbas, Abul K. 011, 016, 029, 034, 675 Ariizumi, Kiyoshi 096, 199 Potter, Christopher S. 442, 453 Rao, Smitha 653 Abbas, Tazeen 229 Armento, Alexander 566, 725 Poumay, Yves 335 Rapisarda, Valentina 679 Abdel-Malek, Zalfa A. 607 Armile, James A. 212 Pourreyron, Celine 486 Rappersberger, Klemens 194, 613 Abdelgawwad, Mohammad 582 Armstrong, April W. 246, 303 Pradhan, Sanjay 108 Rappoport, Joshua 473 Abdul-Wahab, Alya 411 Armstrong, Cheryl A. 520 Prado, Giselle 301 Rashighi, Mehdi 013 Abe, Riichiro 361 Arnold, Steven E. 310 Praetzel-Wunder, Silke 388 Rauch, Tibor 567 Abecasis, Goncalo 438, 440 Arozenius, Helena 006 Pramhed, Anna 006 Rausch, Matthew 028 Abels, Christoph 359 Arron, Sarah 102, 133, 384 Prasad, Atulya 261 Rauscher, Frank J. 646 Abeni, Damiano 417 Artis, Keli 193, 350 Prasad, Ram 578, 579, 591 Rawlings, Anthony V. 339, 364, 372, 387 Achtman, Jordan C. 073 Artomov, Mykyta 134 Pratt, C. H. 442, 453, 454, 455, 468 Razani, Bahram 573 Adachi, Akimasa 220 Asada, Hideo 054 Pratt, Herbert 661 Readhead, Ben 491 Adams, Peter D. 156 Asano, Yoshihide 009, 177 Premi, Sanjay 606, 635 Readio, Nyssa 118 Adase, Chris 337 Asgari, Maryam M. 305 Prens, Errol 221 Reece, Barry 253 Adhami, Vaqar 559 Ashbaugh, Alyssa 509, 510 Presland, Richard 173, 353 Reed, Ann M. 050 Adhikary, Gautam 143, 389 Aspiroz, Carmen 189 Price, Sally 221 Rehder, Paul 458 Adler, Brandon 239, 295, 531, 713 Astry, Brian 557 Price, Thea P. 462, 730 Reichelt, Julia 388 Admani, Shehla 219 Ata, Mohammad O. 581 Price, Vera H. 019, 079, 264 Reichert, Olga 604, 727 Adotama, Prince 329 Atanasova, Velina 426 Privette, Emily 596 Reilly, Devin 142 Afanasiev, Olga 015 Athar, Mohammad 150, 571, 651 Priyamvada, Lalita 046 Reinholdt, Laura G. 442, 455 Afaq, Farrukh 571, 638 Atsugi, Toru 352 Proksch, Ehrhardt 359 Reisman, Scott A. 185 Afshar, Maryam 207 Atwood, Scott 120, 132, 174 Proksch, Joel 185 Remedios, Kelly A. 029 Agak, George W. 407, 531 Atzmony, Lihi 457 Ptacek, Travis 582 Ren, Haobo 169 Agarwal, Ashwin 164, 251 Aust, Samantha 083, 084 Pulit-Penaloza, Joanna A. 045 Rerknimitr, Pawinee 206 Agarwal, Priti 013 Awgulewitsch, Alexander 690 Purnadi, Christy E. 447 Retuerto, Mauricio 215 Aggarwal, Rohit 050 Ayehunie, Seyoum 566 Puzo, Jose 275 Reymermier, Corinne 380 Agón, Pedro 275 Ayithan, Natarajan 544 Reyon, Deepak 435 Ahmad, Israr 581 Azambuja, Ana P. 316, 317, 318 Rezaee, Melika 132, 135, 174, 425 Ahmad, Nihal 654 Aziz, Ahmar 709 Rezaee, Rod 292 Q Ahmed, Rehana L. 612 Qi, Ji 160, 231, 312, 365, 599 Rezusta, Antonio 189 Ahn, Jaewoo 198 Qian, Cheng 261 Ribeiro, Adele H. 363 Ahn, Richard 443 Qian, Ye 092 Rice, Robert H. 366, 389 B Ahn, Sung K. 660 Babineau, Denise 350 Qiang, Jian 592 Richardson, Christopher 008 Ahrns, Hadjh S. 298 Bacchiocchi, Antonella 148, 606, 635 Qiang, Lei 107, 347, 580 Richmond, Jillian 013 Aiba, Setsuya 700 Bachelor, Michael A. 566, 647, 725 Qiao, Pei 077 Rickard, David 506 Akhtar, Nosheen 598 Bae, Jong H. 660 Qiao, Shuxi 609, 650 Riddle, Megan 486 Al-Sadek, Camli 582 Baek, Yoosang 198 Qin, Chuan 687 Ridky, Todd W. 149, 156, 474, 637 Alberico, Stephanie 084 Baer, Janina 679 Qin, Jean 463 Rieger, Kerri 064 Albuquerque, Celina 065 Baerenwald, Devin 138 Qin, Min 531 Rihani, FB 450 Alessi Cesar, Sabrina 250 Bagby, Stacey 624 Qin, Zhaoping 492 Risica, Patricia 322 Alexeev, Vitali 652 Baghdadi, T 692 Qu, Kun 391, 451 Rivera Gonzalez, Guillermo 478 Algazi, Alain 194 Bai, Jing 088 Quaglino, Pietro 194 Roberts, Brett J. 488 Ali, Niwa 675 Baida, Gleb 491 Quan, Taihao 492, 493 Roberts, Janet 672 Alijarde, Roberto 275 Bailey, Irene 174 Quave, Cassandra L. 545 Roberts, Lewis R. 658 Alkelai, A 066 Bak, Soon-Sun 659 Que, Syril Keena 183 Robins, Harlan 082, 225 Ally, Mina S. 132, 174, 315 Bakshi, Pooja 396 Quesenberry, Charles 305 Robinson, Elizabeth S. 056, 202, 596 Almeida, Adam R. 648 Ballard, David H. 536 Quiggle, Ashley 452 Robinson, James 625 Alshehri, Wedad 173 Balooch, Guive 249 Quirk, Brendan 223 Robinson, June K. 105, 158 Alves, Paul 056 Banez, Lionel 251 Qureshi, Abrar A. 167, 178, 299, 304, 311, 323, 324, 325 Robinson, Steven 106, 624, 648 Alvim, Rafael 316, 317, 318 Banga, Ajay K. 063, 338, 362, 396 Robinson, William 106, 624, 648 Amagai, Masayuki 098, 352, 508 Bao, Xiaomin 451 Robinson-Bostom, Leslie 195, 617 Ambrose, Jeffery J. 536 Bar-Hen, Avner 269 Robres, Pilar 189 R Amin, Ahmad S. 260 Baratti, Mariana 525 Raber, Inbar 234, 244 Rock, Fernando 507 Amoh, Yasuyuki 691 Barcellos-Hoff, Mary Helen 580 Rademaker, Alfred 260 Röcken, Martin 136, 140, 420 Anandasabapathy, Niroshana 003, 004, 007 Bardot, Evan 680 Radoja, Nadezda 097 Rodríguez-Arámbula, Adriana 615 Anderson, Abraham 281 Barkoukis, Hope 214 Rady, Peter L. 503 Rogers, John 249 Anderson, Mark S. 028 Barnes, Drew H. 552 Rafael, Nicholas 350 Rogers, T 378 Anderson, Mary E. 511 Barnes, Kathleen 350 Raff, Adam 171 Roggenkamp, Dennis 604, 727 Andl, Claudia D. 711, 735 Baron, Elma D. 584 Ragsdale, Bruce 458 Rojas-Canales, Darling 030 Andl, Thomas 711, 735 Barthel, Steven R. 004 Rahman, Heero N. 677, 678 Romar, George A. 227 Andre-Frei, Valerie 380, 485, 542 Barzegar, Mohammad R. 464, 466 Rai, Taranjit Singh 156 Rompolas, Panteleimon 404, 674 Andrews, J. 259, 395, 705, 730, 733 Barzilai, A 066 Rainer, Barbara 160, 231, 599 Roop, Dennis R. 114, 141, 366, 641 Angra, Divya 112 Basel-Vanagaite, Lina 457 Raj, Nidhin 372 Roopenian, Derry C. 435, 454 Ansell, David 666 Bashir, Hasan 149 Rajiah, Prabhakar 278 Rorke, Ellen 389, 460 Antaya, Richard 436 Bashir, Muhammad 056, 067 Ramachandran, Sarika 051, 081, 279 Rosato, E 497 Antes, Travis 130 Bashkirova, Elizaveta 428 Ramadan, Mohamed 550 Roselino, Ana Maria 065 Aplin, Andrew 107 Basiri, M R. 464 Ramaswami, Sitharam 511, 620 Rosen, Jamie 531 Arave, Rowan 625 Bastien, Philippe 249 Ramirez-Valle, Francisco 555 Rosenbach, Misha 283 Arbieva, Zarema 567 Batazzi, Adriana 144 Ramos, Lavo 146 Rosenbloom, Joel 497, 705, 733 Arbiser, Jack L. 063, 176, 495 Baudouin, Caroline 197, 369 Ramos, Raul 522 Rosenblum, Michael D. 011, 016, 029, 034, 095, 675 Arcaroli, John J. 624 Bauer, Jürgen 136 Randall, Valerie 656, 677, 678 Rosowski, Kathryn A. 662, 694 Archer, Nate 510 Baum, S 066 Randhawa, Manpreet 499 Ross, Andrew L. 639 S128 Journal of Investigative Dermatology (2015), Volume 135 S142 Journal of Investigative Dermatology (2015), Volume 135 114 AUTHOR INDEX AUTHOR INDEX

Arcioni, Marianne 356 Ross,A N 395 Schmidt, Nathan W. 407 Ardeleanu, Marius 169 Ross,Aasi, NicholasSumaira Z.A. 259209 Schmidt, T 218 Ross,Abaci, Russell Hasan E. 351401, 427, 715 Schmults,Arenas, ElsaChrys 182224, 230 Rothstein,Abbas, Abul Brooke K. 649011, 016, 029, 034, 675 Schneider,Ariizumi, LyndaKiyoshi 350096, 199 Rouzard,Abbas, Tazeen Karl 529,229 568 Schneider,Armento, SamanthaAlexander L. 639566, 725 Rubin,Abdel-Malek, Adam Zalfa A. 451607 Schock,Armile, Ashley James M.A. 129,212 223 Rudolf,Abdelgawwad, Jana Mohammad 679582 Schoenborn,Armstrong, KatrinApril W. 484246, 303 Ruenger,Abdul-Wahab, Thomas Alya M. 044,411 434, 595 Schofield,Armstrong, Paul Cheryl N. A. 204,520 442 Rufaut,Abe, Riichiro Nicholas 688361 Schopf,Arnold, Rudolf Steven E. E. 271310 Ruiz-Arguelles,Abecasis, Goncalo Guillermo J. 230438, 440 Schubert,Arozenius, Mark Helena 173006 Russell,Abels, Christoph Chris B. 281359 Schuck,Arron, DesiréeSarah C. 363102, 133, 384 Rybski,Abeni, KristinDamiano 124,417 139 Schufesky,Artis, Keli William 541193, 350 Ryde,Achtman, Anna-Carin Jordan C. 006073 Schulz,Artomov, Claudia Mykyta 420134 Ryu,Adachi, Jubin Akimasa 351220 Schulz,Asada, Jan-Niklas Hideo 484054 Ryu,Adams, Sunhyo Peter D. 520156 Schwan,Asano, JosiannaYoshihide V. 648009, 177 Ryu,Adase, Yunhee Chris 540337 Schwartz,Asgari, Maryam Mary E. M. 450,305 469 Adhami, Vaqar 559 Schwarz,Ashbaugh, Agatha Alyssa 518509, 510 Adhikary, Gautam 143, 389 Schwarz,Aspiroz, Thomas Carmen 518189 SAdler, Brandon 239, 295, 531, 713 Scolyer,Astry, BrianRichard 634557 Sachar,Admani, Moniyka Shehla 307219 Scott,Ata, GlynisMohammad O. 622581 Sage,Adotama, Peter Prince 003329 Scott,Atanasova, Jeffrey F.Velina 292426 Saget,Afanasiev, Julie Olga 380,015 485 Scumpia,Athar, Mohammad Philip O. 574150, 571, 651 Sahu,Afaq, RaviFarrukh 590,571, 593 638 Seielstad,Atsugi, Toru Mark 431,352 443 Saito,Afshar, Nao Maryam 432207 Seiffert-Sinha,Atwood, Scott Kristina 068,120, 069, 132, 070 174 Sajda,Agak, ThomasGeorge W. 068407, 531 Seiler,Atzmony, F Lihi 416457 Sakabe,Agarwal, Jun-ichi Ashwin 588164, 251 Seiverling,Aust, Samantha Elizabeth S. 298083, 084 Sakaguchi,Agarwal, Priti Azumi 340013 Seldin,Awgulewitsch, Lindsey Alexander 371690 Sakaguchi,Aggarwal, MasanobuRohit 621050 Self,Ayehunie, Alyssa Seyoum 333566 Sakamoto,Agón, Pedro Atsushi 716275 Selph,Ayithan, Jacqueline Natarajan 267,544 332, 584 Sakshuwong,Ahmad, Israr Sukolsak 234581 Sen,Azambuja, George Ana P. 430316, 317, 318 Salah,Ahmad, T Nihal 416654 Sengle,Aziz, AhmarGerhard 484709 Salahuddin,Ahmed, Rehana Taufiq L. 203612 Seo, Eun Young 601 Salas-Alanis,Ahn, Jaewoo Julio 486198 Seo, InSeok 623 Salazar,Ahn, Richard Nerea 583443 Seo,B Jimyung 131 Saleh,Ahn, SungI K. 066660 Sepp,Babineau, Norbert Denise 666350 Salmon,Ahrns, Hadjh Michel S. 335298 Serna-Tamayo,Bacchiocchi, CristianAntonella 570148, 606, 635 Samuelov,Aiba, Setsuya L 378700 Seroul,Bachelor, Pierre Michael A. 339566, 647, 725 Samuelsson,Akhtar, Nosheen Kristin 549598 Serre,Bae, Catherine,Jong H. 355,660 357, 358 Sanford,Al-Sadek, James Camli A. 337,582 543 Setaluri,Baek, Yoosang Vijayasaradhi 470,198 618 Sanganee,Alberico, StephanieHitesh 221084 Sethi,Baer, Aisha Janina 306679 Sanlorenzo,Albuquerque, Martina Celina 194,065 409, 613 Seykora,Baerenwald, John Devin 149,138 157, 416 Sanmartín,Alessi Cesar, Rosalía Sabrina 275250 Seymour,Bagby, Stacey Leroy J. 048624 SanMiguel,Alexeev, Vitali Adam J. 553,652 554 Shafizadeh,Baghdadi, TracyT 397692 Santhanam,Algazi, Alain Uma 385,194 605, 697 Shah,Bai, PalakJing 107,088 580 Santilli,Ali, Niwa Scott 278675 Shah,Baida, Parisha Gleb P. 156491 Santos,Alijarde, Leandro Roberto 005,275 505 Shahbazian,Bailey, Irene Jonathan 509174 Sanz,Alkelai, Ignacio A 061066 Shaheen,Bak, Soon-Sun Abdullah 582659 Sapkota,Ally, Mina Bishu S. 045132, 174, 315 Shalbaf,Bakshi, Mohammad Pooja 656396 Sapparapu,Almeida, Adam Gopal R. 018648 Shalbaf,Ballard, Omid David H. 678536 Saraceni,Alshehri, CoreyWedad 458173 Shankar,Balooch, S Guive 157,249 416 Sarig,Alves, O Paul 066,056 218, 378, 395, 450 Shao,Banez, Yuan Lionel 492251 Sarin,Alvim, Kavita Rafael 064,316, 120, 317, 132, 318 135, 174, 410, 425 Shapiro,Banga, JerryAjay K. 673063, 338, 362, 396 Sarkar,Amagai, Mrinal Masayuki K. 263,098, 399, 352, 440, 508 446, 552 Sharma,Bao, Xiaomin Meena 576,451 596 Sasaki,Ambrose, Takako Jeffery J. 502536 Sharma,Bar-Hen, Vinod Avner K. 438269 Sasankan,Amin, Ahmad Priya S. 070260 Sharov,Baratti, Andrey Mariana 679,525 709 Sato,Amoh, Emi Yasuyuki 337691 Sharova,Barcellos-Hoff, Tatyana MaryY. Helen 709,580 731 Sato,Anandasabapathy, Shinichi Niroshana 009,003, 058, 004, 177, 007 188 Sharpe,Bardot, Arlene Evan H. 003680 Saul,Anderson, Melissa Abraham 322281 Shaw,Barkoukis, Fiona M.Hope 146,214 626 Shea, Christopher R. 347 Savoy,Anderson, Leonard Mark S. 229028 Barnes, Drew H. 552 Sawane, Mika 471 Sheen, Yi-Shuan 109, 633 Anderson, Mary E. 511 Barnes, Kathleen 350 Saya, Hideyuki 098 Shellman, Yiqun G. 648 Andl, Claudia D. 711, 735 Baron, Elma D. 584 Sayama, Koji 472 Shemer, Avner 042, 055, 452, 562, 686 Andl, Thomas 711, 735 Barthel, Steven R. 004 Schachner, Lawrence 657 Shen, Chong 401, 427 Andre-Frei, Valerie 380, 485, 542 Barzegar, Mohammad R. 464, 466 Schafer, Christopher 717 Sherratt, Michael J. 387 Andrews, J. 259, 395, 705, 730, 733 Barzilai, A 066 Schafer, Mark 548 Shiau, Chung-Wai 648 Angra, Divya 112 Basel-Vanagaite, Lina 457 Schairer, David O. 713 Shimada, Shinji 002 Ansell, David 666 Bashir, Hasan 149 Scharnitz, Thomas P. 273, 298, 328 Shimizu, Hiroshi 361, 432 Antaya, Richard 436 Bashir, Muhammad 056, 067 Scharschmidt, Tiffany C. 011 Shin, Daniel B. 289, 302, 310 Antes, Travis 130 Bashkirova, Elizaveta 428 Schatton, Tobias 123 Shin, Dong Youn 512 Aplin, Andrew 107 Basiri, M R. 464 Scheu, Alexander 420 Shin, Jung U 017, 252, 556, 732 Arave, Rowan 625 Bastien, Philippe 249 Schieke, Stefan M. 117, 126 Shin, Kyong O. 660 Arbieva, Zarema 567 Batazzi, Adriana 144 Schikowski, Tamara 286, 288, 293 Shin, Kyong-Oh 102 Arbiser, Jack L. 063, 176, 495 Baudouin, Caroline 197, 369 Schilling, Lisa M. 313 Shin, Min Kyeong 217, 481, 483 Schlapbach,Arcaroli, John Christoph J. 072624 Shinkuma,Bauer, Jürgen Satoru 401,136 419, 427 Archer, Nate 510 Baum, S 066 www.jidonline.org S143 S128 Journal of Investigative Dermatology (2015), Volume 135 115 AUTHOR INDEX AUTHOR INDEX

Arcioni, Marianne 356 Shintani, Yoichi 216 Srivastava, Ritesh K. 571 A Aasi, Sumaira Z. 209 Ardeleanu, Marius 169 Shiraishi, Ken 472 St. Claire, Chelsea 644 Abaci, Hasan E. 401, 427, 715 Arenas, Elsa 224, 230 Shomron, N 450 Staeb, Franz 604 Abbas, Abul K. 011, 016, 029, 034, 675 Ariizumi, Kiyoshi 096, 199 Shroff, Anjali 686 Stahle, Mona 431, 443 Abbas, Tazeen 229 Armento, Alexander 566, 725 Shroyer, Kenneth R. 141, 649, 687 Stahley, Sara N. 479 Abdel-Malek, Zalfa A. 607 Armile, James A. 212 Shufesky, William 030 Stanley, John R. 060 Abdelgawwad, Mohammad 582 Armstrong, April W. 246, 303 Shuler, Michael L. 715 Starner, Renny 607 Abdul-Wahab, Alya 411 Armstrong, Cheryl A. 520 Shultz, L 378 Stauber, Jonathan 376 Abe, Riichiro 361 Arnold, Steven E. 310 Shuman, Stewart 570 Stauffer, F 416 Abecasis, Goncalo 438, 440 Arozenius, Helena 006 Sia, Samuel K. 401, 427, 715 Stearns, Timothy M. 052, 439 Abels, Christoph 359 Arron, Sarah 102, 133, 384 Siddiqui, Imtiaz 559 Stefan, Baertschi 476 Abeni, Damiano 417 Artis, Keli 193, 350 Sidhu, Shireen 538 Stefanick, Marcia 315 Achtman, Jordan C. 073 Artomov, Mykyta 134 Sidhu-Malik, Navjeet 291 Stevens, Zachary 566 Adachi, Akimasa 220 Asada, Hideo 054 Siegel, Sarah 258 Stewart, Rachel 694 Adams, Peter D. 156 Asano, Yoshihide 009, 177 Siegfried, Elaine 161, 166 Sticozzi, Claudia 603 Adase, Chris 337 Asgari, Maryam M. 305 Sieling, Peter A. 201 Stimac, Gregory 714 Adhami, Vaqar 559 Ashbaugh, Alyssa 509, 510 Sigurdsson, M I. 175 Stock, Jeffry B. 529, 568 Adhikary, Gautam 143, 389 Aspiroz, Carmen 189 Sigurgeirsson, Baldur 175 Stock, Maxwell 529, 568 Adler, Brandon 239, 295, 531, 713 Astry, Brian 557 Siller, Max 006 Stohl, Lori L. 020, 516, 532 Admani, Shehla 219 Ata, Mohammad O. 581 Silva, Joao S. 065 Stoll, Stefan W. 248, 489 Adotama, Prince 329 Atanasova, Velina 426 Silva, Kathleen A. 052, 435, 439, 661 Stolz, Sabine 286, 293 Afanasiev, Olga 015 Athar, Mohammad 150, 571, 651 Silverberg, Jonathan 239, 295, 308, 320, 321, 327, 330 Straight, Chelsey S. 296 Afaq, Farrukh 571, 638 Atsugi, Toru 352 Silverberg, Nanette B. 308 Strasser, Bettina 390 Afshar, Maryam 207 Atwood, Scott 120, 132, 174 Simon, Daniel I. 037 Strazzulla, Lauren C. 643 Agak, George W. 407, 531 Atzmony, Lihi 457 Simonette, Rebecca 503 Street, Theresa 656 Agarwal, Ashwin 164, 251 Aust, Samantha 083, 084 Simonsson, Carl 549 Streilein, Robert 040 Agarwal, Priti 013 Awgulewitsch, Alexander 690 Simpson, Eric L. 169, 180, 308, 350 Stricklin, George 291, 307 Aggarwal, Rohit 050 Ayehunie, Seyoum 566 Sims, Diane 107, 347 Strieb, Joanne 193 Agón, Pedro 275 Ayithan, Natarajan 544 Sinclair, Rodney 688 Strom, Mark A. 321 Ahmad, Israr 581 Azambuja, Ana P. 316, 317, 318 Singer, Adam 261 Stuart, Philip E. 438, 440, 446 Ahmad, Nihal 654 Aziz, Ahmar 709 Singh, Chandra K. 654 Su, John S. 228 Ahmed, Rehana L. 612 Singh, Rakesh 617 Su, Maureen 152 Ahn, Jaewoo 198 Singh, Suresh B. 367 Su, X 110 Ahn, Richard 443 Singh, Tripti 578, 579, 591 Suarez, Andrea L. 099 B Ahn, Sung K. 660 Babineau, Denise 350 Sinha, Animesh A. 057, 068, 069, 070, 429 Suarez-Farinas, Mayte 049, 055, 085, 190, 198, 266, 280, 392, Ahrns, Hadjh S. 298 Bacchiocchi, Antonella 148, 606, 635 Siprashvili, Zurab 418 394, 445, 686 Aiba, Setsuya 700 Bachelor, Michael A. 566, 647, 725 Sirota, Marina 410 Suga, Hiraku 009, 177, 188 Akhtar, Nosheen 598 Bae, Jong H. 660 Sivaraman, Arunprasad 362 Sugarman, Jeffrey 465 Al-Sadek, Camli 582 Baek, Yoosang 198 Sjödin, Anders 006 Sugaya, Makoto 009, 177, 188 Alberico, Stephanie 084 Baer, Janina 679 Sklar, Samuel 384 Suggs, Amanda K. 584 Albuquerque, Celina 065 Baerenwald, Devin 138 Skountzou, Ioanna 045 Sugihara, Eiji 098 Alessi Cesar, Sabrina 250 Bagby, Stacey 624 Slade, Michelle 605 Sugiri, Dorothee 286 Alexeev, Vitali 652 Baghdadi, T 692 Slapen-Cortenbach, Ineke 411 Sullivan, Keith 251 Algazi, Alain 194 Bai, Jing 088 Slominski, Andrzej T. 345 Sullivan-Whalen, Mary 190 Ali, Niwa 675 Baida, Gleb 491 Smale, Stephen 574 Summers, Beverley 339 Alijarde, Roberto 275 Bailey, Irene 174 Smirin-Yosef, Pola 457 Sumpter, Tina L. 030, 541 Alkelai, A 066 Bak, Soon-Sun 659 Smith, FJD 450 Sun, Bryan 391 Ally, Mina S. 132, 174, 315 Bakshi, Pooja 396 Smith, Susan H. 005, 505, 506, 527 Sun, Hong 602 Almeida, Adam R. 648 Ballard, David H. 536 Snedecor, Elizabeth R. 649, 687 Sun, Lin 536 Alshehri, Wedad 173 Balooch, Guive 249 Snitow, Melinda 685 Sun, Qi 689 Alves, Paul 056 Banez, Lionel 251 Soares, Tania 525 Sun, Richard 381, 400 Alvim, Rafael 316, 317, 318 Banga, Ajay K. 063, 338, 362, 396 Soeberdt, Michael 359 Sun, Shuhong 053 Amagai, Masayuki 098, 352, 508 Bao, Xiaomin 451 Sola, Mario 439 Sun, Xiaojun 560 Ambrose, Jeffery J. 536 Bar-Hen, Avner 269 Solano, Francis 322 Sun, Xiuwen 023 Amin, Ahmad S. 260 Baratti, Mariana 525 Soler, David C. 278 Sun, Zhongbin 383 Amoh, Yasuyuki 691 Barcellos-Hoff, Mary Helen 580 Solomon, Alvin 257 Sundberg, John P. 052, 204, 422, 435, 439, 442, 453, 454, Anandasabapathy, Niroshana 003, 004, 007 Bardot, Evan 680 Song, Peter I. 520 455, 462, 468, 661, 690 Anderson, Abraham 281 Barkoukis, Hope 214 Song, Pu 075 Sung, Clifford 649 Anderson, Mark S. 028 Barnes, Drew H. 552 Song, Quincy 373 Sung, Young-Kwan 659 Anderson, Mary E. 511 Barnes, Kathleen 350 Sontheimer, Richard 087 Suo, Liye 665 Andl, Claudia D. 711, 735 Baron, Elma D. 584 Sotoudeh, Soheila 466 Suozzi, Kathleen C. 119 Andl, Thomas 711, 735 Barthel, Steven R. 004 South, Andrew P. 426, 486 Suto, Asuka 361 Andre-Frei, Valerie 380, 485, 542 Barzegar, Mohammad R. 464, 466 Southall, Michael 499 Suzuki, Shotaro 432 Andrews, J. 259, 395, 705, 730, 733 Barzilai, A 066 Southern, David H. 154 Suzuki, Takahiro 010 Angra, Divya 112 Basel-Vanagaite, Lina 457 Spandau, Dan F. 154, 398, 477, 736 Svoboda, Robert 488 Ansell, David 666 Bashir, Hasan 149 Spaunhurst, Katrina 315 Swanson, Brian 169 Antaya, Richard 436 Bashir, Muhammad 056, 067 Speaker, Tycho 469 Swerlick, Robert 479 Antes, Travis 130 Bashkirova, Elizaveta 428 Spiegelman, Vladimir 618 Swetter, Susan 291, 307 Aplin, Andrew 107 Basiri, M R. 464 Spitale, Robert 130, 244, 265 Swindell, William R. 263, 399, 440, 446, 552, 723 Arave, Rowan 625 Bastien, Philippe 249 Sprecher, Eli 066, 218, 378, 395, 450 Swinka, Bruna B. 363 Arbieva, Zarema 567 Batazzi, Adriana 144 Spritz, Richard A. 640 Swope, Viki 607 Arbiser, Jack L. 063, 176, 495 Baudouin, Caroline 197, 369 Sproule, Thomas J. 435, 454 Syed, Deeba N. 559, 598 Arcaroli, John J. 624 Bauer, Jürgen 136 Squeri, Michael V. 501 Archer, Nate 510 Baum, S 066 Srikantha, Rupasree 083 S128 Journal of Investigative Dermatology (2015), Volume 135 S144 Journal of Investigative Dermatology (2015), Volume 135 116 AUTHOR INDEX AUTHOR INDEX

Arcioni, Marianne 356 TA Torre-Cabala, Carlos 179 Ardeleanu, Marius 169 Tabin,Aasi, Sumaira Clifford Z. 696209 Torres-Álvarez, Bertha 615 Tabrizi,Abaci, HasanMina E. 692401, 427, 715 Toth,Arenas, Daniel Elsa 567224, 230 Tada,Abbas, Yayoi Abul K. 009,011, 177 016, 029, 034, 675 Trang,Ariizumi, Trinh Kiyoshi 312096, 199 Tadeu,Abbas, Ana Tazeen 662229 Travers,Armento, Jeffrey Alexander B. 154,566, 590, 725 593 Takahashi,Abdel-Malek, Naomi Zalfa A. 177,607 188 Trembley,Armile, James Janeen A. H. 612212 Takakura,Abdelgawwad, Nobuyuki Mohammad 471582 Tripathi,Armstrong, Raghav April W. 334246, 303 Takamori,Abdul-Wahab, Kenji Alya 340,411 519 Truong,Armstrong, Hong-An Cheryl A. 011,520 016, 029, 034, 675 Takashima,Abe, Riichiro Shota 432361 Tsai,Arnold, Ching-Yi Steven E. 059310 Takei,Abecasis, Kentaro Goncalo 377438, 440 Tsai,Arozenius, Kenneth Helena 110006 Takeo,Abels, MakotoChristoph 664,359 689 Tsao,Arron, Hensin Sarah 134,102, 616, 133, 636 384 Takeshita,Abeni, Damiano Junko 289,417 302, 310 Tschachler,Artis, Keli Erwin 388,193, 390, 350 594 Taketo,Achtman, Mark Jordan M. C. 689073 Tso,Artomov, Simon Mykyta 411134 Takiguchi,Adachi, Akimasa Tetsuya 551220 Tsoi,Asada, Lam Hideo C. 248,054 438, 440 Talasila,Adams, PeterSreya D. 036,156 165 Tsou,Asano, Hong Yoshihide 539009, 177 Talbot,Adase, C.Chris Conover 599337 Tsuboi,Asgari, Ryoji Maryam M. 368305 Tamai,Adhami, Katsuto Vaqar 408559 Tsuchiyama,Ashbaugh, AlyssaKenichiro 700509, 510 Tamimi,Adhikary, Iman Gautam A. 581143, 389 Tsuda,Aspiroz, Hidetoshi Carmen 374189 Tamura,Adler, Brandon Deborah 112239, 295, 531, 713 Tsukamoto,Astry, Brian K 157557 Tan,Admani, Caroline Shehla Z. 234219 Tsunemi,Ata, Mohammad Yuichiro O. 009581 Tang,Adotama, Hsin PrinceYao 060329 Tsuruta,Atanasova, Daisuke Velina 666426 Tang,Afanasiev, Jean Y. Olga 120,015 132, 135, 174, 209, 315, 418, 425 Tu,Athar, Chia-Ling Mohammad 699150, 571, 651 Tang,Afaq, LingzhenFarrukh 619571, 638 Tucker,Atsugi, Danielle Toru 116352 Tar,Afshar, Moses Maryam 713207 Tuckey,Atwood, Robert Scott C. 345120, 132, 174 Taravati,Agak, George Keyon W. 095407, 531 Tung,Atzmony, Joyce Lihi 244457 Tatarsky,Agarwal, P Ashwin 066164, 251 Turatti,Aust, SamanthaAline 065083, 084 Taube,Agarwal, Janis Priti M. 144,013 274, 365 Turner,Awgulewitsch, Matthew J.Alexander 048690 Taylor,Aggarwal, Chase Rohit 711050 Turrentine,Ayehunie, Jake Seyoum E. 096566 Taylor,Agón, PedroKimberly E. 443275 Two,Ayithan, Aimee Natarajan 193,544 282 Taylor,Ahmad, Michael Israr 616,581 636 Tworoger,Azambuja, Shelley Ana P. 324316, 317, 318 Taylor,Ahmad, Patricia Nihal 193654 Tyldsley,Aziz, Ahmar Amanda 533,709 553, 554 Teague,Ahmed, Jessica Rehana E. L. 026,612 072, 082, 225, 415, 421 Tyring, Stephen K. 503 Tedeschi,Ahn, Jaewoo Carine 336198 Tedesco,Ahn, Richard Marinella 719443 B Tejasvi,Ahn, Sung Trilokraj K. 438,660 440 UBabineau, Denise 350 Teles,Ahrns, Rosane Hadjh M.S. 572298 Uchida,Bacchiocchi, Yoshikazu Antonella 102,148, 381 606, 635 Tepper,Aiba, Setsuya Clifford G. 074700 Udey,Bachelor, Mark MichaelC. A. 669566, 647, 725 Terstegen,Akhtar, Nosheen Lara 604,598 727 Udono,Bae, Jong Heiichiro H. 500660 Teske,Al-Sadek, Noelle Camli 181,582 186 Uitto,Baek, Jouni Yoosang 259,198 378, 395, 422, 426, 462, 464, 466, Thakuria,Alberico, ManishaStephanie 123084 Baer, Janina 468,679 497, 652, 692, 705, 730, 733 Thangapazham,Albuquerque, Celina Rajesh L. 441065 Ulerio,Baerenwald, Grace Devin 238,138 272 Tharp,Alessi MichaelCesar, Sabrina 567250 Umegaki-Arao,Bagby, Stacey Noriko 401624 Theodosakis,Alexeev, Vitali Nicholas 632652 Umehara,Baghdadi, Yoshie T 340,692 519 ThirtharAlgazi, AlainPalanivelu, Vetrichevvel 707194 Ungar,Bai, Jing Benjamin 042,088 255 Tholpady,Ali, Niwa Sunil S. 154,675 477, 736 Ungewickell,Baida, Gleb Alexander 341491 Thomas,Alijarde, Nancy Roberto E. 152275 Urman,Bailey, Nicole Irene M. 120174 Thomas,Alkelai, APaul 473066 Ushio,Bak, Soon-SunHiroko 526659 Thompson,Ally, Mina PaulS. 631132, 174, 315 Bakshi, Pooja 396 Thorleifsdottir,Almeida, Adam Ragna R. H. 175648 Ballard, David H. 536 ThornAlshehri, Leeson, Wedad Daniel 385173 VBalooch, Guive 249 Thyagarajan-Sahu,Alves, Paul Anita 048056 Vahidnezhad,Banez, Lionel Hassan 464,251 466, 692 Tian,Alvim, Chao Rafael 244316, 317, 318 Vaid,Banga, Mudit Ajay K. 578063, 338, 362, 396 Tian,Amagai, Tian Masayuki 041,098, 043, 352, 147 508 Valacchi,Bao, Xiaomin Giuseppe 603451 Tiao,Ambrose, Janice Jeffery J. 056,536 184 Valdimarsson,Bar-Hen, Avner Helgi 175269 Tice,Amin, Colin Ahmad S. 367260 Valenti,Baratti, Lionel Mariana 547525 Tigelaar,Amoh, Yasuyuki Robert E. 031691 Valla-Dury,Barcellos-Hoff, Loreleï Mary Helen 542580 Timares,Anandasabapathy, Laura Niroshana 651003, 004, 007 Van,Bardot, Hieu Evan 106680 Tirgan,Anderson, Michael Abraham H. 266281 VanBarkoukis, Allen, Margot Hope 449214 Titeux,Anderson, Matthias Mark S. 405028 VanBarnes, De Water, Drew LivingstonH. 706552 Tkacheva, Olga 030, 541 Anderson, Mary E. 511 VanBarnes, Smeden, Kathleen Jeroen 343350 Tohyama, Mikiko 472 VanBrocklin, Matthew 625 Andl, Claudia D. 711, 735 Baron, Elma D. 584 Tokura, Yoshiki 010, 588 Vandenberg, Katherine 301 Andl, Thomas 711, 735 Barthel, Steven R. 004 Tolar, Jakub 408, 411, 486 Vanderberghe, Matthieu 608 Andre-Frei, Valerie 380, 485, 542 Barzegar, Mohammad R. 464, 466 Tom, Wynnis 219 Vandergriff, Travis 199 Andrews, J. 259, 395, 705, 730, 733 Barzilai, A 066 Tomayko, Mary 200 Vandeven, Natalie 015, 196 Angra, Divya 112 Basel-Vanagaite, Lina 457 Tominaga, Mitsutoshi 340, 519 Varki, Ajit 702 Ansell, David 666 Bashir, Hasan 149 Tominaga, Shin-ichi 374 Vasquez, Kimberly S. 011 Antaya, Richard 436 Bashir, Muhammad 056, 067 Tong, Lana 643 Vasquez, Rebecca 276 Antes, Travis 130 Bashkirova, Elizaveta 428 Tongdee, Emily 301 Vázquez, Nayeli 224 Aplin, Andrew 107 Basiri, M R. 464 Tonnesen, Marcia 649 Vedak, Priyanka 171 Arave, Rowan 625 Bastien, Philippe 249 Toriz, Guillermo 224 Vegfors, Jenny 546 Arbieva, Zarema 567 Batazzi, Adriana 144 Torkamani, Niloufar 688 Velez, Antonio 644 Arbiser, Jack L. 063, 176, 495 Baudouin, Caroline 197, 369 Torkelson, Jessica 428 Velho, Paulo 525, 563 Arcaroli, John J. 624 Torre, Eduardo 265 Ventrella,Bauer, Jürgen Rosa 723136 Archer, Nate 510 Baum, S 066 www.jidonline.org S145 S128 Journal of Investigative Dermatology (2015), Volume 135 117 AUTHOR INDEX AUTHOR INDEX

Arcioni, Marianne 356 Vera-Alvarez, Jesus 189, 583 Ward, Keith 185 A Aasi, Sumaira Z. 209 Ardeleanu, Marius 169 Verhaegen, Monique E. 124 Ward, Nicole L. 033, 037, 263, 495, 530, 561 Abaci, Hasan E. 401, 427, 715 Arenas, Elsa 224, 230 Veys, Paul 411 Warren, Lachlan J. 228 Abbas, Abul K. 011, 016, 029, 034, 675 Ariizumi, Kiyoshi 096, 199 Vezeridis, Michael 617 Warren, Maxine 479 Abbas, Tazeen 229 Armento, Alexander 566, 725 Vianney, Anne 542 Warshauer, E 378 Abdel-Malek, Zalfa A. 607 Armile, James A. 212 Viera-Damiani, Gislaine 525, 563 Warshaw, Erin M. 291 Abdelgawwad, Mohammad 582 Armstrong, April W. 246, 303 Vierkoetter, Andrea 286, 288, 293 Warton, E. Margaret 305 Abdul-Wahab, Alya 411 Armstrong, Cheryl A. 520 Villasante, Alexandra C. 657 Washburn, Newell 550 Abe, Riichiro 361 Arnold, Steven E. 310 Vinnakota, Ravi 294 Wasserman, Wyeth 734 Abecasis, Goncalo 438, 440 Arozenius, Helena 006 Vinokour, Elena 491 Watanabe, Daisuke 702 Abels, Christoph 359 Arron, Sarah 102, 133, 384 Virtucio-Frates, Charlotte 507 Watanabe, Rei 026, 041, 225, 415 Abeni, Damiano 417 Artis, Keli 193, 350 Vitcov, Giselle 384 Waterfield, Michael 028 Achtman, Jordan C. 073 Artomov, Mykyta 134 Viviani, Fabrice 505 Watkins, Stephanie 047 Adachi, Akimasa 220 Asada, Hideo 054 Vleugels, Ruth Ann 242, 279 Watson, Rachel E. 387 Adams, Peter D. 156 Asano, Yoshihide 009, 177 Vodo, D. 066, 378, 450 Watt, Stephen 486 Adase, Chris 337 Asgari, Maryam M. 305 Voegeli, Rainer 339, 364, 372, 387 Webb, Corey 529, 568 Adhami, Vaqar 559 Ashbaugh, Alyssa 509, 510 Vogel, Stefanie 524 Webb, R. Chad 249 Adhikary, Gautam 143, 389 Aspiroz, Carmen 189 vonKoschembahr, Anne 607 Webber, Lorraine 221 Adler, Brandon 239, 295, 531, 713 Astry, Brian 557 Voorhees, John J. 139, 254, 438, 440, 446, 492, 493 Weber-Sanders, Melissa 277, 563 Admani, Shehla 219 Ata, Mohammad O. 581 Voronkov, Michael 529, 568 Wei, Chungwen 061 Adotama, Prince 329 Atanasova, Velina 426 Vossoughi, Mohammad 293 Wei, Gabrielle 531 Afanasiev, Olga 015 Athar, Mohammad 150, 571, 651 Vozheiko, Tracy 124 Wei, Maria L. 622 Afaq, Farrukh 571, 638 Atsugi, Toru 352 Vreeken, Rob 343 Wei, Zhi 646 Afshar, Maryam 207 Atwood, Scott 120, 132, 174 Vujic, Igor 194, 409, 613 Weick, Jack 124 Agak, George W. 407, 531 Atzmony, Lihi 457 Vujic, Marin 194 Weihermann, Ana Cristina 363 Agarwal, Ashwin 164, 251 Aust, Samantha 083, 084 Vyas, Ritva 245, 292, 326, 332 Weiler, Nicole 344 Agarwal, Priti 013 Awgulewitsch, Alexander 690 Weinberg, Wendy C. 142 Aggarwal, Rohit 050 Ayehunie, Seyoum 566 Weiner, Adam 606, 635 Agón, Pedro 275 Ayithan, Natarajan 544 Weinstock, Martin A. 178, 195, 291, 307, 322, 617 W Ahmad, Israr 581 Azambuja, Ana P. 316, 317, 318 Wada, Akino 716 Weisman, Jeffery A. 536 Ahmad, Nihal 654 Aziz, Ahmar 709 Wagner, John 408 Wek, Ronald C. 398 Ahmed, Rehana L. 612 Wagner, John A. 020, 532 Welch, Elizabeth Z. 069 Ahn, Jaewoo 198 Wahl, James K. 488 Wenck, Horst 604, 727 Ahn, Richard 443 Wainwright, Derek 047 Wendelschafer-Crabb, Gwen 247 B Ahn, Sung K. 660 Babineau, Denise 350 Wakamatsu, Kazumasa 606, 635 Weng, Qing Yu 171 Ahrns, Hadjh S. 298 Bacchiocchi, Antonella 148, 606, 635 Wakefield, Joan 400 Weng, Zhiping 571 Aiba, Setsuya 700 Bachelor, Michael A. 566, 647, 725 Walker, Joanna L. 307 Wenglén, Christina 006 Akhtar, Nosheen 598 Bae, Jong H. 660 Wallace, Hilary 707 Werth, Victoria 056, 067, 073, 080, 184, 202, 291, 576, Al-Sadek, Camli 582 Baek, Yoosang 198 Wallisch, Silvia 606, 635 596 Alberico, Stephanie 084 Baer, Janina 679 Walsh, Laura 351 West, Dennis P. 260 Albuquerque, Celina 065 Baerenwald, Devin 138 Wan, Fengyi 144 Westerhof, Wiete 047 Alessi Cesar, Sabrina 250 Bagby, Stacey 624 Wan, Yinsheng 629 Wetter, David A. 235 Alexeev, Vitali 652 Baghdadi, T 692 Wang, Annie 167 Weyerbacher, Jonathan 154, 590 Algazi, Alain 194 Bai, Jing 088 Wang, Bingcheng 723 Wheeler, D A. 110 Ali, Niwa 675 Baida, Gleb 491 Wang, Dian 462 Wheeler, Hayley 064 Alijarde, Roberto 275 Bailey, Irene 174 Wang, Eddy H. 673 Whelan, Harry 223 Alkelai, A 066 Bak, Soon-Sun 659 Wang, Etienne 720 Whelan, Timothy M. 535 Ally, Mina S. 132, 174, 315 Bakshi, Pooja 396 Wang, Frank 254 White, Steven R. 347 Almeida, Adam R. 648 Ballard, David H. 536 Wang, Gang 012, 023, 076, 077, 078, 319, 383, 587 Whitson, Ramon 132 Alshehri, Wedad 173 Balooch, Guive 249 Wang, Grace Y. 116 Widelitz, Randal 717 Alves, Paul 056 Banez, Lionel 251 Wang, Honglin 088 Wieder, Thomas 136, 140, 420 Alvim, Rafael 316, 317, 318 Banga, Ajay K. 063, 338, 362, 396 Wang, Huijun 456 Wikramanayake, Tongyu C. 370, 610 Amagai, Masayuki 098, 352, 508 Bao, Xiaomin 451 Wang, Jeffery W. 083 Wikstroem, Peter 364 Ambrose, Jeffery J. 536 Bar-Hen, Avner 269 Wang, Jenny W. 656, 678 Wilbert, D 155 Amin, Ahmad S. 260 Baratti, Mariana 525 Wang, Ji-an 168, 441 Wilbert, Dawn 124 Amoh, Yasuyuki 691 Barcellos-Hoff, Mary Helen 580 Wang, Joshua 646 Wilcox, George L. 247 Anandasabapathy, Niroshana 003, 004, 007 Bardot, Evan 680 Wang, L 157 Wiles, Michael V. 435 Anderson, Abraham 281 Barkoukis, Hope 214 Wang, Li 544 Williams, Joshua D. 609, 650 Anderson, Mark S. 028 Barnes, Drew H. 552 Wang, Qixuan 693, 695 Williams, Kevin J. 067 Anderson, Mary E. 511 Barnes, Kathleen 350 Wang, Sijia 288, 293 Williamson, David 225 Andl, Claudia D. 711, 735 Baron, Elma D. 584 Wang, Sung-Min 537 Winge, M. C. 412 Andl, Thomas 711, 735 Barthel, Steven R. 004 Wang, Timothy 250, 314 Winthrop, Kevin 258 Andre-Frei, Valerie 380, 485, 542 Barzegar, Mohammad R. 464, 466 Wang, Weiyi 570 Wolchok, Jedd 146 Andrews, J. 259, 395, 705, 730, 733 Barzilai, A 066 Wang, Xiao-Qi 373, 480, 644 Wolpowitz, Deon 205, 269 Angra, Divya 112 Basel-Vanagaite, Lina 457 Wang, Xiaowen 319 Wolterink, Liza 552 Ansell, David 666 Bashir, Hasan 149 Wang, Xinyi 490, 712 Wondrak, Georg T. 565, 609, 650 Antaya, Richard 436 Bashir, Muhammad 056, 067 Wang, Yanhan 513 Wong, Gerard C. 407 Antes, Travis 130 Bashkirova, Elizaveta 428 Wang, Ying 430 Wong, Henry K. 027 Aplin, Andrew 107 Basiri, M R. 464 Wang, Yu 509, 510 Wong, HK Helene 499 Arave, Rowan 625 Bastien, Philippe 249 Wang, Yunmei 037 Wong, Jillian W. 622 Arbieva, Zarema 567 Batazzi, Adriana 144 Wang, Zhengke 498 Wong, Sunny 111 Arbiser, Jack L. 063, 176, 495 Baudouin, Caroline 197, 369 Wang, Zhenping 560, 608 Wood, Fiona 707 Arcaroli, John J. 624 Bauer, Jürgen 136 Ward, Chris 221 Woodley, David T. 408, 490, 500, 712, 729 Archer, Nate 510 Baum, S 066 Ward, Christopher M. 666 Woodward, David 656, 678 S128 Journal of Investigative Dermatology (2015), Volume 135 S146 Journal of Investigative Dermatology (2015), Volume 135 118 AUTHOR INDEX AUTHOR INDEX

Arcioni, Marianne 356 Word,A Andrew P. 199 Yin, Jinghua 456 Ardeleanu, Marius 169 Wrammert,Aasi, Sumaira Jens Z. 046209 Yin, Natalie 657 Wright,Abaci, HasanNatalie E. A. 242,401, 279 427, 715 Yin,Arenas, Xianyong Elsa 431224, 230 Wright,Abbas, SheilaAbul K. 486011, 016, 029, 034, 675 Ying,Ariizumi, Zuolin Kiyoshi 101096, 199 Wu,Abbas, Ching Tazeen Shuang 701229 Yo,Armento, Kazuyuki Alexander 434,566, 595 725 Wu,Abdel-Malek, Diane Zalfa A. 412607 Yokouchi,Armile, James Mariko A. 352212 Wu,Abdelgawwad, Dinghong Mohammad 093582 Yokoyama,Armstrong, Wayne April W. 021246, 303 Wu,Abdul-Wahab, Hsin-Jung Alya 477,411 736 Yokozeki,Armstrong, Hiroo Cheryl A. 564520 Wu,Abe, Joseph Riichiro 113,361 463 Yoshida,Arnold, Takeshi Steven E. 213,310 346, 350 Wu,Abecasis, Julie H. Goncalo 503438, 440 Yoshimasu,Arozenius, Takashi Helena 062006 Wu,Abels, Pinru Christoph 003,359 007 Yoshizaki,Arron, Sarah Ayumi 058102, 133, 384 Wu,Abeni, Shaowei Damiano 178,417 299, 304, 311, 323, 325 Yosipovitch,Artis, Keli Gil 187193, 350 Wu,Achtman, Shu-Hui Jordan C. 437073 You,Artomov, Zhaoyang Mykyta 032134 Wu,Adachi, Xuesong Akimasa 117,220 126, 534, 544 Young,Asada, Chen Hideo N. 229054 Wu,Adams, Yueh-Feng Peter D. 676156 Young,Asano, Christie Yoshihide 389009, 177 Wyborski,Adase, Chris Russell 663337 Young,Asgari, Christina Maryam M. 460305 Adhami, Vaqar 559 Young,Ashbaugh, Richard Alyssa A. 636509, 510 Adhikary, Gautam 143, 389 Youssefian,Aspiroz, Carmen Leila 464,189 466, 692 XAdler, Brandon 239, 295, 531, 713 Yu,Astry, Hsin-Su Brian 103557 Xia,Admani, Li Shehla 456219 Yu,Ata, Pei-Yi Mohammad O. 539581 Xian,Adotama, Wujing Prince 407329 Yu,Atanasova, Richard Velina 673426 Xiao,Afanasiev, Chunying Olga 053015 Yu,Athar, Yang Mohammad 407150, 571, 651 Xiao,Afaq, Yueyuan Farrukh 456571, 638 Yufit,Atsugi, Tatyana Toru 631,352 724, 728, 731 Xing,Afshar, Luzhou Maryam 019,207 089, 090 Yun,Atwood, Seok KyunScott 600120, 132, 174 Xing,Agak, Xianying George W. 263,407, 399, 531 552 Yuspa,Atzmony, Stuart Lihi H. 097,457 137, 153 Xiong,Agarwal, Fang Ashwin 498164, 251 Yusuf,Aust, Nabiha Samantha 581,083, 582 084 Xu,Agarwal, Guiwen Priti 456013 Awgulewitsch, Alexander 690 Xu,Aggarwal, Guoliang Rohit 709050 Ayehunie, Seyoum 566 Xu,Agón, Hui Pedro 591275 ZAyithan, Natarajan 544 Xu,Ahmad, Jin Israr 244,581 265 Zamarrón,Azambuja, Alicia Ana P. 151316, 317, 318 Xu,Ahmad, Linghui Nihal 020654 Zane,Aziz, Lee Ahmar 507709 Xu,Ahmed, Mingang Rehana L. 685612 Zarbafian, Misha 086 Xu,Ahn, Wen Jaewoo 143198 Zare, Richard N. 209 Xu,Ahn, Yanan Richard 456443 ZargarB Shoshtari, Homayoun 326 Xu,Ahn, Yang Sung K. 139660 Zeeli,Babineau, T Denise 066,350 218 Xu,Ahrns, Yaohui Hadjh G. S. 618298 Zehnder,Bacchiocchi, Ashley Antonella 412148, 606, 635 Xu,Aiba, Yiru Setsuya 139700 Zeinali,Bachelor, S Michael A. 464,566, 466 647, 725 Xu,Akhtar, Yuhuan Nosheen 687598 Zender,Bae, Jong Chad H. 292660 Al-Sadek, Camli 582 Zeng,Baek, Wangyong Yoosang 620198 Alberico, Stephanie 084 Zengler,Baer, Janina Karsten 193679 YAlbuquerque, Celina 065 Zhai,Baerenwald, Zili Devin 640138 Yaguchi,Alessi Cesar, Tomonori Sabrina 002250 Zhang,Bagby, Chen Stacey 104624 Yakubovskaya,Alexeev, Vitali Marianna 491652 Zhang,Baghdadi, Jennifer T Y. 040,692 113, 463 Yamada,Algazi, Alain Masao 551194 Zhang,Bai, Jing Jiajing 451088 Yamamoto,Ali, Niwa Ai 293675 Zhang,Baida, Jieyu Gleb 468491 Yamamoto,Alijarde, Roberto Mami 368275 Zhang,Bailey, Juan Irene 288174 Yamamoto,Alkelai, A Takenobu 551066 Zhang,Bak, Soon-Sun Lianfeng 687659 Yamanishi,Ally, Mina HaruyoS. 368132, 174, 315 Zhang,Bakshi, Lingjuan Pooja 337,396 522 Yamasaki,Almeida, AdamKenshi R. 700648 Zhang,Ballard, Tinghu David H. 636536 Yamauchi,Alshehri, Wedad Takeshi 700173 Zhang,Balooch, Weigang Guive 456249 Yan,Alves, Zihao Paul 262056 Zhang,Banez, Xiang Lionel 423251 Yang,Alvim, Catherine Rafael 195316, 317, 318 Zhang,Banga, Xiaoli Ajay K. 027063, 338, 362, 396 Yang,Amagai, Chao Masayuki 026098, 352, 508 Zhang,Bao, XiaominXiaoling 113,451 463 Yang,Ambrose, Gink Jeffery J. 538536 Zhang,Bar-Hen, Xiaoru Avner 602269 Yang,Amin, Hanjun Ahmad S. 139260 Zhang,Baratti, Xu Mariana 687525 Yang,Amoh, Hoseong Yasuyuki Steven 274691 Zhang,Barcellos-Hoff, Xuejun Mary Helen 431580 Yang,Anandasabapathy, Liang-Tung Niroshana 437003, 004, 007 Zhang,Bardot, Yajun Evan 075680 Yang,Anderson, Nicole Abraham 365281 Zhang,Barkoukis, Yi Hope 032214 Yang,Anderson, Ning Mark S. 141,028 687 Zhang,Barnes, Yuan Drew H. 076552 Yang, Shi 614 Zhao, Baozhong 107, 347 Anderson, Mary E. 511 Barnes, Kathleen 350 Yang, Thomas 674 Zhao, Jiahui 456 Andl, Claudia D. 711, 735 Baron, Elma D. 584 Yang, X 157, 416 Zhao, Tao 456 Andl, Thomas 711, 735 Barthel, Steven R. 004 Yang, Yajun 288 Zhao, Wei 367 Andre-Frei, Valerie 380, 485, 542 Barzegar, Mohammad R. 464, 466 Yang, Yong 456 Zhao, Xinyi 668 Andrews, J. 259, 395, 705, 730, 733 Barzilai, A 066 Yang, Zhihua 456 Zhao, Yi 367 Angra, Divya 112 Basel-Vanagaite, Lina 457 Yao, Catherine 120, 132 Zhao, Zhongming 138 Ansell, David 666 Bashir, Hasan 149 Yao, Cheng 482 Zhen, Hanson 428 Antaya, Richard 436 Bashir, Muhammad 056, 067 Yardley, Nathan P. 150 Zheng, Ji 723 Antes, Travis 130 Bashkirova, Elizaveta 428 Yarker, Joanne 679 Zheng, Liangtao 456 Aplin, Andrew 107 Basiri, M R. 464 Yeh, Chih-Chun 109, 633 Zheng, Qi 060, 071, 553, 554 Arave, Rowan 625 Bastien, Philippe 249 Yeh, Iwei 622 Zheng, Wenxin 144 Arbieva, Zarema 567 Batazzi, Adriana 144 Yelistratova, Lola 256 Zheng, Yajun 367 Arbiser, Jack L. 063, 176, 495 Baudouin, Caroline 197, 369 Yen, Chien-Mei 671 Zheng, Zhenlong 131 Arcaroli, John J. 624 Yeung, Howa 283, 284 Zhou,Bauer, Eray Jürgen Yihui 456136 Archer, Nate 510 Baum, S 066 www.jidonline.org S147 S128 Journal of Investigative Dermatology (2015), Volume 135 119 AUTHOR INDEX AUTHOR INDEX

Arcioni, Marianne 356 Zhou, Hua 524 Zic, John A. 138 A Aasi, Sumaira Z. 209 Ardeleanu, Marius 169 Zhou, Jin 139 Zillikens, D 066 Abaci, Hasan E. 401, 427, 715 Arenas, Elsa 224, 230 Zhou, Jing 436, 444, 458 Zippin, Jonathan H. 146, 148, 626 Abbas, Abul K. 011, 016, 029, 034, 675 Ariizumi, Kiyoshi 096, 199 Zhou, Li 093 Zito, Giovanni 119 Abbas, Tazeen 229 Armento, Alexander 566, 725 Zhou, Yasheen 507 Zou, Memgchen 729 Abdel-Malek, Zalfa A. 607 Armile, James A. 212 Zhu, Gefei 130, 234 Zubek, Amanda 694 Abdelgawwad, Mohammad 582 Armstrong, April W. 246, 303 Zhu, Jiajun 156 Zuk, Alexandra 484 Abdul-Wahab, Alya 411 Armstrong, Cheryl A. 520 Zhu, Yucui 115, 150 Zuo, Yagang 091 Abe, Riichiro 361 Arnold, Steven E. 310 Zhu, Zheng 305 Zwerner, Jeffrey 138 Abecasis, Goncalo 438, 440 Arozenius, Helena 006 Zhuang, Linghang 367 Abels, Christoph 359 Arron, Sarah 102, 133, 384 Zhuang, Yong 663 Abeni, Damiano 417 Artis, Keli 193, 350 Achtman, Jordan C. 073 Artomov, Mykyta 134 Adachi, Akimasa 220 Asada, Hideo 054 Adams, Peter D. 156 Asano, Yoshihide 009, 177 Adase, Chris 337 Asgari, Maryam M. 305 Adhami, Vaqar 559 Ashbaugh, Alyssa 509, 510 Adhikary, Gautam 143, 389 Aspiroz, Carmen 189 Adler, Brandon 239, 295, 531, 713 Astry, Brian 557 Admani, Shehla 219 Ata, Mohammad O. 581 Adotama, Prince 329 Atanasova, Velina 426 Afanasiev, Olga 015 Athar, Mohammad 150, 571, 651 Afaq, Farrukh 571, 638 Atsugi, Toru 352 Afshar, Maryam 207 Atwood, Scott 120, 132, 174 Agak, George W. 407, 531 Atzmony, Lihi 457 Agarwal, Ashwin 164, 251 Aust, Samantha 083, 084 Agarwal, Priti 013 Awgulewitsch, Alexander 690 Aggarwal, Rohit 050 Ayehunie, Seyoum 566 Agón, Pedro 275 Ayithan, Natarajan 544 Ahmad, Israr 581 Azambuja, Ana P. 316, 317, 318 Ahmad, Nihal 654 Aziz, Ahmar 709 Ahmed, Rehana L. 612 Ahn, Jaewoo 198 Ahn, Richard 443 B Ahn, Sung K. 660 Babineau, Denise 350 Ahrns, Hadjh S. 298 Bacchiocchi, Antonella 148, 606, 635 Aiba, Setsuya 700 Bachelor, Michael A. 566, 647, 725 Akhtar, Nosheen 598 Bae, Jong H. 660 Al-Sadek, Camli 582 Baek, Yoosang 198 Alberico, Stephanie 084 Baer, Janina 679 Albuquerque, Celina 065 Baerenwald, Devin 138 Alessi Cesar, Sabrina 250 Bagby, Stacey 624 Alexeev, Vitali 652 Baghdadi, T 692 Algazi, Alain 194 Bai, Jing 088 Ali, Niwa 675 Baida, Gleb 491 Alijarde, Roberto 275 Bailey, Irene 174 Alkelai, A 066 Bak, Soon-Sun 659 Ally, Mina S. 132, 174, 315 Bakshi, Pooja 396 Almeida, Adam R. 648 Ballard, David H. 536 Alshehri, Wedad 173 Balooch, Guive 249 Alves, Paul 056 Banez, Lionel 251 Alvim, Rafael 316, 317, 318 Banga, Ajay K. 063, 338, 362, 396 Amagai, Masayuki 098, 352, 508 Bao, Xiaomin 451 Ambrose, Jeffery J. 536 Bar-Hen, Avner 269 Amin, Ahmad S. 260 Baratti, Mariana 525 Amoh, Yasuyuki 691 Barcellos-Hoff, Mary Helen 580 Anandasabapathy, Niroshana 003, 004, 007 Bardot, Evan 680 Anderson, Abraham 281 Barkoukis, Hope 214 Anderson, Mark S. 028 Barnes, Drew H. 552 Anderson, Mary E. 511 Barnes, Kathleen 350 Andl, Claudia D. 711, 735 Baron, Elma D. 584 Andl, Thomas 711, 735 Barthel, Steven R. 004 Andre-Frei, Valerie 380, 485, 542 Barzegar, Mohammad R. 464, 466 Andrews, J. 259, 395, 705, 730, 733 Barzilai, A 066 Angra, Divya 112 Basel-Vanagaite, Lina 457 Ansell, David 666 Bashir, Hasan 149 Antaya, Richard 436 Bashir, Muhammad 056, 067 Antes, Travis 130 Bashkirova, Elizaveta 428 Aplin, Andrew 107 Basiri, M R. 464 Arave, Rowan 625 Bastien, Philippe 249 Arbieva, Zarema 567 Batazzi, Adriana 144 Arbiser, Jack L. 063, 176, 495 Baudouin, Caroline 197, 369 Arcaroli, John J. 624 Bauer, Jürgen 136 Archer, Nate 510 Baum, S 066

S128 Journal of Investigative Dermatology (2015), Volume 135 S148 Journal of Investigative Dermatology (2015), Volume 135 120 KEYWORD INDEX KEYWORD INDEX

Acne vulgaris 014, 197, 207, 212, 267, 273, 296, 328, Cell Senescence 121, 122, 140, 420 Acne vulgaris 014, 197, 207, 212, 267, 273, 296, 328, Cell Senescence 121, 122, 140, 420 407, 531, 543, 548, 656 407, 531, 543, 548, 656 Cell-Cell Communication 058, 673, 723 Cell-Cell Communication 058, 673, 723 Adipose 471, 478, 522, 716, 719 Adipose 471, 478, 522, 716, 719 Ceramide 376, 397, 400, 608, 660 Ceramide 376, 397, 400, 608, 660 Adverse Drug Reaction 051, 162, 179, 194, 235, 240, 257, 273, Adverse Drug Reaction 051, 162, 179, 194, 235, 240, 257, 273, 417 Chemokine 010, 012, 033, 050, 163, 441, 532, 652 417 Chemokine 010, 012, 033, 050, 163, 441, 532, 652 AKT 107, 113, 115, 150, 423, 625, 629, 692 Chemotherapy 227, 307, 362, 617, 626, 640, 645, 650, AKT 107, 113, 115, 150, 423, 625, 629, 692 Chemotherapy 227, 307, 362, 617, 626, 640, 645, 650, 657 657 Aldo-keto reductase 684 Aldo-keto reductase 684 Children 036, 165, 166, 432 Children 036, 165, 166, 432 Allergic Contact Dermatitis 192, 215, 367, 414, 549, 564 Allergic Contact Dermatitis 192, 215, 367, 414, 549, 564 Cigarette smoke 313 Cigarette smoke 313 Allergy 048 Allergy 048 CLASI 186 CLASI 186 Alopecia, non-scaring 008, 019, 052, 079, 238, 264, 272, 277, Alopecia, non-scaring 008, 019, 052, 079, 238, 264, 272, 277, 657, 658, 670, 672, 673, 686, 690 co-morbidity 073, 219, 260, 263, 278, 289, 306, 310, 657, 658, 670, 672, 673, 686, 690 co-morbidity 073, 219, 260, 263, 278, 289, 306, 310, 329 329 Alopecia, scarring 089, 090, 665, 666, 684 Alopecia, scarring 089, 090, 665, 666, 684 Cohort Study 178, 181, 182, 186, 191, 222, 276, 304, Cohort Study 178, 181, 182, 186, 191, 222, 276, 304, Antimalarials 235 307, 316, 317, 318, 323, 406 Antimalarials 235 307, 316, 317, 318, 323, 406 Antimicrobial peptide 102, 193, 348, 400, 407, 518, 519, 520, collagen 058, 081, 084, 254, 405, 418, 432, 435, Antimicrobial peptide 102, 193, 348, 400, 407, 518, 519, 520, collagen 058, 081, 084, 254, 405, 418, 432, 435, 526, 546, 562 476, 485, 487, 492, 494, 576, 577, 596, 526, 546, 562 476, 485, 487, 492, 494, 576, 577, 596, 600, 627, 710 600, 627, 710 Aryl Hydrocarbon Receptor 319, 375, 588, 589 Aryl Hydrocarbon Receptor 319, 375, 588, 589 Copy Number Variation 447 Copy Number Variation 447 Atopic dermatitis 006, 017, 022, 034, 036, 042, 048, 055, Atopic dermatitis 006, 017, 022, 034, 036, 042, 048, 055, 085, 159, 163, 165, 166, 167, 169, 180, Corneocytes 366, 368 085, 159, 163, 165, 166, 167, 169, 180, Corneocytes 366, 368 193, 197, 213, 215, 246, 252, 275, 280, 193, 197, 213, 215, 246, 252, 275, 280, 308, 320, 321, 327, 330, 340, 343, 346, COX2 588, 615, 678 308, 320, 321, 327, 330, 340, 343, 346, COX2 588, 615, 678 347, 350, 352, 367, 394, 452, 507, 508, 347, 350, 352, 367, 394, 452, 507, 508, 510, 519, 523, 535, 556, 686 CTCL 101, 117, 126, 138, 147, 177, 179, 188, 510, 519, 523, 535, 556, 686 CTCL 101, 117, 126, 138, 147, 177, 179, 188, 222, 225, 237, 332, 415, 421, 423, 534 222, 225, 237, 332, 415, 421, 423, 534 Bioengineered Tissue 355, 356, 357, 358, 647, 715, 725 Bioengineered Tissue 355, 356, 357, 358, 647, 715, 725 cutaneous nerve fibers 108, 205, 727 cutaneous nerve fibers 108, 205, 727 Biologics 037, 051, 061, 216, 258, 271, 278, 417, Biologics 037, 051, 061, 216, 258, 271, 278, 417, 616, 655 cytokines 006, 010, 040, 044, 054, 056, 072, 089, 616, 655 cytokines 006, 010, 040, 044, 054, 056, 072, 089, 140, 216, 281, 514, 516, 527, 532, 543, 140, 216, 281, 514, 516, 527, 532, 543, Blistering Disease 060, 061, 065, 077, 078, 083, 084, 091, 620, 628 Blistering Disease 060, 061, 065, 077, 078, 083, 084, 091, 620, 628 200, 285, 479, 571 200, 285, 479, 571 Dendritic Cell 001, 003, 007, 025, 031, 032, 040, 044, Dendritic Cell 001, 003, 007, 025, 031, 032, 040, 044, 667 103, 125, 179, 271, 379, 521, 558, 565 Botulinum toxin 667 103, 125, 179, 271, 379, 521, 558, 565 BRAF 465, 617, 618, 626, 633, 638, 644 Dermal Papilla 476, 660, 674, 687 BRAF 465, 617, 618, 626, 633, 638, 644 Dermal Papilla 476, 660, 674, 687 Burns 261, 707, 730 Dermatitis 024, 161, 227, 240, 359, 368 Burns 261, 707, 730 Dermatitis 024, 161, 227, 240, 359, 368 C. albicans 521 Dermatomyositis 050, 056, 064, 073, 080, 087, 172, 202, C. albicans 521 Dermatomyositis 050, 056, 064, 073, 080, 087, 172, 202, 410 410 Calcium-Sensing Receptor 353, 699 Calcium-Sensing Receptor 353, 699 Dermoscopy 183, 387 Dermoscopy 183, 387 Cancer cell invasion 119, 122, 129, 146, 412, 474, 498, 638 Cancer cell invasion 119, 122, 129, 146, 412, 474, 498, 638 desmocollin 382, 488 desmocollin 382, 488 Carcinogenesis 021, 074, 099, 105, 108, 109, 112, 116, Carcinogenesis 021, 074, 099, 105, 108, 109, 112, 116, 118, 119, 120, 123, 125, 127, 128, 130, desmoglein 018, 066, 068, 092, 164, 479, 488 118, 119, 120, 123, 125, 127, 128, 130, desmoglein 018, 066, 068, 092, 164, 479, 488 137, 140, 141, 142, 143, 144, 145, 148, 137, 140, 141, 142, 143, 144, 145, 148, 153, 154, 155, 174, 199, 268, 274, 285, Desmoplakin 475 153, 154, 155, 174, 199, 268, 274, 285, Desmoplakin 475 299, 412, 651, 674 299, 412, 651, 674 Disease Severity 171, 184, 251, 267, 402, 458 Disease Severity 171, 184, 251, 267, 402, 458 Cathelicidin 206, 522, 574 Cathelicidin 206, 522, 574 Dlx3 097, 669 Dlx3 097, 669 Cell adhesion 068, 071, 363, 382, 475, 488, 694, 704, Cell adhesion 068, 071, 363, 382, 475, 488, 694, 704, 714 DNA damage 067, 116, 496, 580, 586, 606, 607, 611, 714 DNA damage 067, 116, 496, 580, 586, 606, 607, 611, 635, 650 635, 650 Cell Based Therapy 047, 059, 405, 408, 411, 418, 659, 719, Cell Based Therapy 047, 059, 405, 408, 411, 418, 659, 719, 736 Drug Allergy 162, 206 736 Drug Allergy 162, 206 Cell cycle 097, 113, 344, 374, 474, 506, 589, 616, Drug delivery 063, 338, 351, 362, 373, 396, 536, 713, Cell cycle 097, 113, 344, 374, 474, 506, 589, 616, Drug delivery 063, 338, 351, 362, 373, 396, 536, 713, 624, 663 715 624, 663 715 Cell migration 026, 104, 113, 500, 555, 557, 608, 697, EGFR 139, 473, 489, 589 Cell migration 026, 104, 113, 500, 555, 557, 608, 697, EGFR 139, 473, 489, 589 698, 703, 714, 728, 729 698, 703, 714, 728, 729

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Acne vulgaris 014, 197, 207, 212, 267, 273, 296, 328, Cell Senescence 121, 122, 140, 420 Endoplasmic Reticulum Stress 087, 571 Herpes Zoster 202 407, 531, 543, 548, 656 Cell-Cell Communication 058, 673, 723 Eosinophil 067, 083, 439, 556 Hidradenitis Suppurativa 221, 306, 309 Adipose 471, 478, 522, 716, 719 Ceramide 376, 397, 400, 608, 660 Eph Receptor 100, 473, 723 High-Throughput Sequencing 060, 082, 110, 192, 425, 444, 452 Adverse Drug Reaction 051, 162, 179, 194, 235, 240, 257, 273, 417 Chemokine 010, 012, 033, 050, 163, 441, 532, 652 Epidemiology 191, 204, 228, 231, 237, 239, 250, 279, Higher Order Chromatin AKT 283, 284, 107,285, 113,286, 115,287, 150,288, 423,290, 625,291, 629, 692 OrganizationChemotherapy 156, 709227, 307, 362, 617, 626, 640, 645, 650, 292, 293, 294, 295, 296, 297, 298, 299, 657 Aldo-keto reductase 301, 302, 684303, 304, 305, 307, 308, 310, Histone deacetyase 393, 403, 602 311, 314, 316, 317, 318, 320, 321, 322, Children 036, 165, 166, 432 Allergic Contact Dermatitis323, 324, 192,325, 215,327, 367,330, 414,332, 549,333, 564334 Host defense 456, 521, 545, 560, 570, 572 Cigarette smoke 313 Epidermal AllergyBarrier 180, 217, 048335, 338, 339, 342, 343, 345, Human Skin Graft 428, 719 347, 349, 351, 354, 355, 357, 358, 359, CLASI 186 Alopecia, non-scaring 360, 362, 008,364, 019,368, 052,370, 079,372, 238,373, 264,375, 272, 277,Hydration 217, 249, 316, 317, 339, 369, 390, 499 379, 381, 657,386, 658,388, 670,390, 672,391, 673,396, 686,400, 690 co-morbidity 073, 219, 260, 263, 278, 289, 306, 310, 402, 452, 562, 569, 653 Ichthyosis 195, 458329 Alopecia, scarring 089, 090, 665, 666, 684 Epidermal Morphogenesis 133, 337, 371, 378, 380, 381, 389, 404, ImmunizationCohort Study 035, 039,178, 043 181, 182, 186, 191, 222, 276, 304, Antimalarials 477, 679, 235681 307, 316, 317, 318, 323, 406 Immunomodulation 001, 006, 020, 024, 028, 030, 049, 086, Epidermal AntimicrobialProgenitor Cells peptide 118, 430, 102,679, 193,680, 348,688 400, 407, 518, 519, 520, collagen 093, 221,058, 238, 081, 281, 084, 407, 254, 565 405, 418, 432, 435, 526, 546, 562 476, 485, 487, 492, 494, 576, 577, 596, Epidermolysis Bullosa 200, 228, 361, 408, 411, 418, 419, 426, Immunosuppression 022, 158,600, 414, 627, 591 710 Aryl Hydrocarbon Receptor428, 435, 319,466, 375,486, 588,490, 589712 ImmunotherapyCopy Number Variation002, 046,447 050, 051, 059, 076, 089, 090, ExtracellularAtopic matrix dermatitis 253, 254, 006,363, 017,385, 022,387, 034,477, 036,481, 042,482, 048, 055, 094, 095, 123, 127, 136, 164, 172, 192, 483, 484, 085,486, 159,487, 163,490, 165,492, 166,493, 167,498, 169, 180, Corneocytes 194, 655366, 368 502, 577, 193,600, 197,601, 213,702, 215,710, 246,712, 252,718 275, 280, 308, 320, 321, 327, 330, 340, 343, 346,Infantile HemangiomaCOX2 436 588, 615, 678 Filaggrin 347, 350, 347,353, 350,366, 352,372, 367,386, 394,389, 452,390, 507, 508, 510 510, 519, 523, 535, 556, 686 InflammationCTCL 005, 014,101, 023, 117, 026, 126, 042, 138, 049, 147, 062, 177, 066, 179, 188, 074, 076,222, 077, 225, 078, 237, 090, 332, 127, 415, 144, 421, 163, 423, 534 Follicular GrowthBioengineered Tissue 677, 678, 355,695 356, 357, 358, 647, 715, 725 170, 173, 176, 185, 190, 198, 199, 203, cutaneous nerve fibers 214, 218,108, 220, 205, 242, 727 243, 248, 344, 359, FoxP3 Biologics 034, 065, 037,518 051, 061, 216, 258, 271, 278, 417, 364, 367, 376, 395, 399, 510, 511, 514, 616, 655 cytokines 516, 528,006, 529, 010, 530, 040, 534, 044, 538, 054, 540, 056, 547, 072, 089, Gene Copy Number Variation 106 552, 558,140, 559, 216, 561, 281, 566, 514, 567, 516, 568, 527, 571, 532, 543, Blistering Disease 060, 061, 065, 077, 078, 083, 084, 091, 573, 590,620, 615, 628 640, 669, 676, 702, 727 Gene Inhibition 659, 661 200, 285, 479, 571 Innate immunityDendritic Cell 077, 078,001, 086, 003, 091, 007, 504, 025, 509, 031, 513, 032, 520, 040, 044, Gene-EnvironmentBotulinum Interaction toxin 393, 597 667 531, 535,103, 540, 125, 541, 179, 543, 271, 544, 379, 560, 521, 562, 558, 565 567, 570, 574 Genetic AssociationBRAF 064, 195, 465,248, 617,435, 618,436, 626,438, 633,442, 638,443, 644 Dermal Papilla 476, 660, 674, 687 449, 690 Integrins 474, 484, 496, 501, 557, 706 Burns 261, 707, 730 Dermatitis 024, 161, 227, 240, 359, 368 Genome wide association study 070, 238, 244, 431, 461 Interferon 057, 064, 086, 136, 161, 206, 420, 551, C. albicans 521 Dermatomyositis 574, 698,050, 711 056, 064, 073, 080, 087, 172, 202, Genomic Instabilty 106, 128, 136, 145 410 Calcium-Sensing Receptor 353, 699 Interleukin 069, 177, 335, 384, 523, 552, 569, 576, Genomics 057, 101, 110, 134, 135, 156, 198, 200, Dermoscopy 615, 651183, 387 Cancer cell invasion 263, 431, 119,440, 122,444, 129,446, 146,447, 412,448, 474,449, 498, 638 450, 451, 459, 464, 465, 470, 554, 661, Internet desmocollin 158, 226,382, 312 488 Carcinogenesis 683, 708, 021,734 074, 099, 105, 108, 109, 112, 116, 118, 119, 120, 123, 125, 127, 128, 130,Irritant desmoglein 379 018, 066, 068, 092, 164, 479, 488 Glucocorticoid Receptor 491 137, 140, 141, 142, 143, 144, 145, 148, 153, 154, 155, 174, 199, 268, 274, 285,Itch Desmoplakin 187, 188,475 205, 213, 236, 269, 340, 369, Graft-versus-host skin disease 038, 044, 299,173, 412,262 651, 674 517, 519, 535 Disease Severity 171, 184, 251, 267, 402, 458 Growth factorCathelicidin 045, 052, 206,109, 522,125, 574188, 472, 478, 480, Keratinocytes 012, 088, 103, 144, 195, 259, 337, 340, 489, 500, 729, 735 Dlx3 341, 349,097, 356, 669 357, 365, 374, 377, 380, Cell adhesion 068, 071, 363, 382, 475, 488, 694, 704, 382, 383, 388, 393, 398, 399, 401, 403, HaCaT cells 575, 711 714 DNA damage 413, 437,067, 450, 116, 460, 496, 469, 580, 475, 586, 479, 606, 489, 607, 611, 506, 511,635, 523, 650 526, 540, 546, 551, 557, Hair FollicleCell Based Therapy 277, 370, 047,371, 059,389, 405,449, 408,459, 411,467, 418,584, 659, 719, 559, 560, 586, 587, 598, 602, 603, 669, 610, 641, 736657, 658, 659, 660, 666, 668, Drug Allergy 684, 694,162, 698, 206 699, 700, 701, 706, 716, 671, 672, 674, 675, 676, 677, 678, 681, 720, 727, 735 Cell cycle 682, 687, 097,688, 113,690, 344,691, 374,693, 474,694, 506,695, 589, 616, Drug delivery 063, 338, 351, 362, 373, 396, 536, 713, 696, 717 624, 663 Ki67 385, 583715

Hedgehog Cell migration 111, 115, 026,132, 104,141, 113,274, 500,687 555, 557, 608, 697,Lipid EGFR 067, 209,139, 219, 473, 275, 489, 342, 589 343, 376, 397, 698, 703, 714, 728, 729 594, 656 Hemangioma 436 www.jidonline.org S149 S150 Journal of Investigative Dermatology (2015), Volume 135 122 KEYWORD INDEX KEYWORD INDEX

Acne vulgaris 014, 197, 207, 212, 267, 273, 296, 328, Cell Senescence 121, 122, 140, 420 Lipid Rafts 335 Pachyonychia Congenita 469 407, 531, 543, 548, 656 Cell-Cell Communication 058, 673, 723 MCL-1 621, 648 Pain 324 Adipose 471, 478, 522, 716, 719 Ceramide 376, 397, 400, 608, 660 Melanin 075, 453, 585, 606, 623, 637, 653 Pathway Analysis 104, 187, 264, 461, 613, 677 Adverse Drug Reaction 051, 162, 179, 194, 235, 240, 257, 273, 417 Chemokine 010, 012, 033, 050, 163, 441, 532, 652 Melanoma 002, 096, 098, 099, 106, 107, 109, 134, Patient Safety 226, 258, 301 148, 152, 178, 201, 245, 250, 270, 292, AKT 107, 113, 115, 150, 423, 625, 629, 692 Chemotherapy 227, 307, 362, 617, 626, 640, 645, 650, 300, 305, 311, 313, 315, 322, 326, 331, Pediatric Dermatology 161, 207, 320, 348, 424 657 333, 338, 409, 412, 470, 612, 613, 614, Aldo-keto reductase 684 616, 617, 618, 620, 621, 622, 624, 625, Photocarcinogenesis 151, 210, 578, 579, 581, 591, 592, 597 Children 036, 165, 166, 432 626, 628, 629, 631, 632, 633, 634, 636, Allergic Contact Dermatitis 192, 215, 367, 414, 549, 564 638, 639, 640, 642, 643, 644, 645, 646, Photodamage 160, 210, 224, 247, 253, 366, 581, 585, Cigarette smoke 313 648, 649, 650, 654, 655 587, 596, 600, 601, 604, 609, 611 Allergy 048 CLASI 186 Merkel cell 015, 123, 124, 196, 241, 256, 680 Physician Behavior 273, 322 Alopecia, non-scaring 008, 019, 052, 079, 238, 264, 272, 277, 657, 658, 670, 672, 673, 686, 690 co-morbidity 073, 219, 260, 263, 278, 289, 306, 310, Microarray 069, 070, 079, 264, 266, 394, 429, 477, Pigmentation 087, 224, 311, 372, 453, 599, 623, 627, 329 599, 601, 736 630, 635, 637, 647, 689 Alopecia, scarring 089, 090, 665, 666, 684 Cohort Study 178, 181, 182, 186, 191, 222, 276, 304, Microbiology 041, 176, 189, 503, 525, 548, 563 Polyomavirus 124, 256, 503 Antimalarials 235 307, 316, 317, 318, 323, 406 Microbiome 011, 038, 180, 193, 215, 508, 513, 533, Post-Chemotherapy Alopecia 610 Antimicrobial peptide 102, 193, 348, 400, 407, 518, 519, 520, collagen 058, 081, 084, 254, 405, 418, 432, 435, 537, 542, 553, 554, 582 526, 546, 562 476, 485, 487, 492, 494, 576, 577, 596, Protease Receptor 498 600, 627, 710 Microneedles 035, 223, 550 Aryl Hydrocarbon Receptor 319, 375, 588, 589 Proteomics 252, 341, 473, 671 Copy Number Variation 447 miRNA 129, 130, 355, 358, 383, 433, 463, 469, Atopic dermatitis 006, 017, 022, 034, 036, 042, 048, 055, 470, 528, 578, 579, 598, 627, 711 Psoriasis 001, 010, 012, 027, 033, 037, 049, 053, 085, 159, 163, 165, 166, 167, 169, 180, Corneocytes 366, 368 055, 063, 072, 076, 082, 088, 093, 095, 193, 197, 213, 215, 246, 252, 275, 280, Monoclonal Antibody 164 175, 198, 203, 208, 211, 214, 216, 219, 308, 320, 321, 327, 330, 340, 343, 346, COX2 588, 615, 678 220, 229, 233, 248, 258, 260, 263, 278, 347, 350, 352, 367, 394, 452, 507, 508, Mouse Models 033, 037, 038, 054, 091, 114, 141, 147, 281, 282, 289, 302, 303, 310, 312, 325, 510, 519, 523, 535, 556, 686 CTCL 101, 117, 126, 138, 147, 177, 179, 188, 152, 155, 204, 388, 394, 422, 437, 441, 383, 384, 392, 399, 402, 406, 413, 431, 222, 225, 237, 332, 415, 421, 423, 534 442, 453, 454, 455, 462, 468, 478, 494, 438, 440, 443, 445, 446, 457, 495, 501, Bioengineered Tissue 355, 356, 357, 358, 647, 715, 725 495, 509, 517, 530, 534, 544, 564, 625, 506, 511, 512, 514, 515, 517, 527, 528, cutaneous nerve fibers 108, 205, 727 658, 661, 673, 681, 726 530, 538, 544, 546, 552, 555, 558, 559, Biologics 037, 051, 061, 216, 258, 271, 278, 417, 561, 566, 587 616, 655 cytokines 006, 010, 040, 044, 054, 056, 072, 089, Myeloid Derived Suppressor 140, 216, 281, 514, 516, 527, 532, 543, Cells 096 Psychodermatology 073, 306 Blistering Disease 060, 061, 065, 077, 078, 083, 084, 091, 620, 628 200, 285, 479, 571 Nanotechnology 002, 024, 373, 413, 480, 531 Psychological stress 271 Dendritic Cell 001, 003, 007, 025, 031, 032, 040, 044, Botulinum toxin 667 103, 125, 179, 271, 379, 521, 558, 565 Natural Extract 022, 217, 385, 481, 545, 547 PTEN 495 BRAF 465, 617, 618, 626, 633, 638, 644 Dermal Papilla 476, 660, 674, 687 Neoplasia 174, 191, 416 Quality Reporting Initiatives 167 Burns 261, 707, 730 Dermatitis 024, 161, 227, 240, 359, 368 Nerve 111, 187, 247, 269, 336, 532, 561, 691 Radiotherapy 185, 593 C. albicans 521 Dermatomyositis 050, 056, 064, 073, 080, 087, 172, 202, Neurokin-1 Receptor 030, 541 Reactive Oxygen Species 151, 341, 496, 575, 593, 721 410 Calcium-Sensing Receptor 353, 699 Neuropeptide 020, 247, 344 Regeneration 117, 404, 670, 671, 676, 682, 689, 691, Dermoscopy 183, 387 693, 709, 717, 721, 722, 728, 736 Cancer cell invasion 119, 122, 129, 146, 412, 474, 498, 638 Next-Generation Sequencing 071, 138, 225, 442, 444, 447, 533, 553, desmocollin 382, 488 554, 708 Regulatory T cell 009, 011, 016, 028, 029, 065, 518, 591, Carcinogenesis 021, 074, 099, 105, 108, 109, 112, 116, 675 118, 119, 120, 123, 125, 127, 128, 130, desmoglein 018, 066, 068, 092, 164, 479, 488 Non-Melanoma Skin Cancers 007, 120, 130, 131, 133, 135, 150, 154, 137, 140, 141, 142, 143, 144, 145, 148, 183, 199, 209, 250, 287, 299, 315, 331, Retinoic Acid 424, 499 153, 154, 155, 174, 199, 268, 274, 285, Desmoplakin 475 334, 425, 583 299, 412, 651, 674 RNA 501 Disease Severity 171, 184, 251, 267, 402, 458 Noncoding RNA 409, 434, 595 Cathelicidin 206, 522, 574 RNA-seq 095, 153, 282, 440 Dlx3 097, 669 Notch Signaling 121 Cell adhesion 068, 071, 363, 382, 475, 488, 694, 704, ROR 584 714 DNA damage 067, 116, 496, 580, 586, 606, 607, 611, OT-1 031 635, 650 Rosacea 197, 244 Cell Based Therapy 047, 059, 405, 408, 411, 418, 659, 719, Oxidative Stress 075, 149, 157, 185, 437, 493, 590, 593, 736 Drug Allergy 162, 206 594, 603, 609, 619, 722 S100 generic 353 Cell cycle 097, 113, 344, 374, 474, 506, 589, 616, Drug delivery 063, 338, 351, 362, 373, 396, 536, 713, p21 586 Scar 329, 707, 732 624, 663 715 p38 MAP kinase 068, 592 Sebaceous gland 334, 656 Cell migration 026, 104, 113, 500, 555, 557, 608, 697, EGFR 139, 473, 489, 589 698, 703, 714, 728, 729 p63 142, 451, 662 Seborrheic dermatitis 269, 370

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Acne vulgaris 014, 197, 207, 212, 267, 273, 296, 328, Cell Senescence 121, 122, 140, 420 Senescence 142, 156, 377, 434, 594 Translational Regulation 398 407, 531, 543, 548, 656 Cell-Cell Communication 058, 673, 723 Serine Proteinase Inhibitor 364 Translational Research 004, 013, 059, 101, 110, 176, 209, 223, Adipose 471, 478, 522, 716, 719 251, 265, 280, 351, 410, 415, 421, 423, Ceramide 376, 397, 400, 608, 660 Shh 120, 150 446, 486, 516, 536, 538, 632, 639, 682 Adverse Drug Reaction 051, 162, 179, 194, 235, 240, 257, 273, 417 Chemokine 010, 012, 033, 050, 163, 441, 532, 652 Signaling 027, 031, 045, 054, 139, 146, 148, 377, TRPV 205 AKT 401, 403, 107,460, 113,472, 115,492, 150,493, 423,524, 625,573, 629, 692 Chemotherapy 227, 307, 362, 617, 626, 640, 645, 650, 592, 607, 619, 620, 629, 644, 685, 701 TSLP 021, 732657 Aldo-keto reductase 684 siRNA 450, 487, 642 Tuberous Childrensclerosis complex 168, 491036, 165, 166, 432 Allergic Contact Dermatitis 192, 215, 367, 414, 549, 564 Skin Homeostasis 339, 352, 371, 430, 439, 451, 458, 463, Tumor GeneticsCigarette smoke 099, 132,313 134, 135, 138, 174, 241, 425, Allergy 499, 605, 048630, 637 465 CLASI 186 Skin ModelsAlopecia, non-scaring 083, 111, 008,342, 019,404, 052,405, 079,433, 238,476, 264,505, 272, 277,Tumor Immunology 007, 009, 015, 021, 032, 047, 104, 114, 539, 566, 657,604, 658,647, 670,695, 672,700, 673,724, 686,725 690 co-morbidity 177, 201,073, 420, 219, 504, 260, 651 263, 278, 289, 306, 310, 329 Skin tumorAlopecia, cells scarring 004, 100, 089,132, 090,137, 665,151, 666,153, 684155, 223, Tumor Microenvironment 009, 108, 114, 122, 152, 256, 441, 490, 225, 612 Cohort Study 504 178, 181, 182, 186, 191, 222, 276, 304, Antimalarials 235 307, 316, 317, 318, 323, 406 Skin-resident T cells 013, 017, 019, 026, 029, 034, 035, 039, Ultraviolet Irradiation 112, 157, 190, 210, 224, 234, 313, 314, Antimicrobial peptide 040, 041, 102,043, 193,072, 348,147, 400,208, 407,227, 518,262, 519, 520, collagen 315, 331,058, 333, 081, 345, 084, 354, 254, 482, 405, 524, 418, 529, 432, 435, 415, 555 526, 546, 562 568, 576,476, 578, 485, 579, 487, 580, 492, 582, 494, 584, 576, 585, 577, 596, 590, 595,600, 597, 627, 598, 710 602, 604, 605, 606, Sphingosine-1-PhosphateAryl Hydrocarbon Receptor102 319, 375, 588, 589 607, 608, 609, 611, 621, 635 Copy Number Variation 447 Squamous Atopiccell carcinoma dermatitis 097, 100, 006,102, 017,105, 022,107, 034,119, 036,129, 042,133, 048, 055,Vaccination 003, 004, 008, 014, 025, 032, 039, 043, 139, 143, 085,146, 159,149, 163,157, 165,158, 166,178, 167,182, 169, 180, Corneocytes 045, 046,366, 330 368 416, 580, 193,583 197, 213, 215, 246, 252, 275, 280, 308, 320, 321, 327, 330, 340, 343, 346,Vaccinia VirusCOX2 570 588, 615, 678 Staphylococcus Aureus 212, 213, 347,350, 350,509, 352,520, 367,522, 394,545, 452,548 507, 508, 510, 519, 523, 535, 556, 686 Vascular InflammationCTCL 052, 162,101, 203, 117, 439, 126, 471, 138, 525, 147, 734 177, 179, 188, Stem cell 117, 118, 143, 384, 401, 408, 427, 428, 222, 225, 237, 332, 415, 421, 423, 534 Bioengineered Tissue 430, 467, 355,624, 356,641, 357,646, 358,648, 647,662, 715,666, 725 Vascular Permeability 230, 471, 547, 715 668, 675, 685, 688, 689, 700, 708, 716, cutaneous nerve fibers 108, 205, 727 Biologics 720, 724, 037,731, 051,735 061, 216, 258, 271, 278, 417,VEGF 103, 137, 734 616, 655 cytokines 006, 010, 040, 044, 054, 056, 072, 089, Sunless and Indoor Tanning 270, 284, 314 Vitamin D3 190, 275,140, 345, 216, 699, 281, 726 514, 516, 527, 532, 543, Blistering Disease 060, 061, 065, 077, 078, 083, 084, 091, 620, 628 Th1 030, 460, 200,564 285, 479, 571 Vitiligo 013, 047, 075, 287, 304, 319, 619, 641, Dendritic Cell 652 001, 003, 007, 025, 031, 032, 040, 044, Th17 Botulinum toxin 005, 020, 667027, 041, 042, 082, 085, 093, 103, 125, 179, 271, 379, 521, 558, 565 221, 505 Voriconazole 149 BRAF 465, 617, 618, 626, 633, 638, 644 Dermal Papilla 476, 660, 674, 687 Th2 048, 085, 255, 686 Warburg effect 126, 632 Burns 261, 707, 730 Dermatitis 024, 161, 227, 240, 359, 368 Tight Junction 346, 352, 381 Wnt 088, 274, 365, 662, 664, 670, 685, 693 C. albicans 521 Dermatomyositis 050, 056, 064, 073, 080, 087, 172, 202, Tissue Homeostasis 391, 664 Wound Healing 016, 098,410 232, 454, 480, 484, 497, 500, Calcium-Sensing Receptor 353, 699 533, 567, 701, 702, 703, 704, 705, 706, TLR 467, 512, 524, 551, 581 Dermoscopy 707, 709,183, 710, 387 712, 714, 717, 720, 721, Cancer cell invasion 119, 122, 129, 146, 412, 474, 498, 638 722, 723, 724, 725, 726, 728, 729, 731, Tolerance 003, 011, 018, 028, 058, 061 desmocollin 732, 733382, 488 Carcinogenesis 021, 074, 099, 105, 108, 109, 112, 116, Topical 005, 348, 118,396, 119,416, 120,505, 123,529, 125,565, 127,568 128, 130, desmoglein 018, 066, 068, 092, 164, 479, 488 137, 140, 141, 142, 143, 144, 145, 148, 153, 154, 155, 174, 199, 268, 274, 285, Desmoplakin 475 299, 412, 651, 674 Disease Severity 171, 184, 251, 267, 402, 458 Cathelicidin 206, 522, 574 Dlx3 097, 669 Cell adhesion 068, 071, 363, 382, 475, 488, 694, 704, 714 DNA damage 067, 116, 496, 580, 586, 606, 607, 611, 635, 650 Cell Based Therapy 047, 059, 405, 408, 411, 418, 659, 719, 736 Drug Allergy 162, 206

Cell cycle 097, 113, 344, 374, 474, 506, 589, 616, Drug delivery 063, 338, 351, 362, 373, 396, 536, 713, 624, 663 715

Cell migration 026, 104, 113, 500, 555, 557, 608, 697, EGFR 139, 473, 489, 589 698, 703, 714, 728, 729

www.jidonline.org S149 S152 Journal of Investigative Dermatology (2015), Volume 135 124 SID Governance

Abstract Paul Bergstresser, MD Section Editors Associate Editors Reviewers Immediate Past President Masayuki Amagai Martine Bagol Lisa Beck Boris Bastian The SID is grateful to the following Richard Gallo, MD/PhD Vladimir Botchkarev Jurgen Becker individuals for review of abstracts. Secretary-Treasurer Paul E. Bowden Carola Berking Richard Clark Mark Berneburg Committee on Barbara Gilchrest, MD Tatiana Efimova Tilo Biedermann Scientific Programs JID Editor Meenhard Herlyn Wendy B. Bollag S. Wright Caughman, MD, Sam Hwang Luca Borradori ex officio Directors Ethan A. Lerner Jan Nico Bouwes Bavinck Richard Gallo, MD/PhD, ex offico Cheng-Ming Chuong, MD/PhD John McGrath Joke Bouwslra Anthony Gaspari, MD, Co-Chair James T. Elder, MD, PhD W. H. Irwin Mclean Leena Bruckner-Tuderman Sam Hwang, MD/PhD Janet A. Fairley, MD Tamar Nijsten Julide Celebi Dan Kaplan, MD/PhD Maranke I. Koster, PhD Thomas Schwarz Cheng-Ming Chuang Ethan Lerner, MD/PhD Andrew P. Kowalczyk, PhD Vijayasaradhi Setaluri Rachael A. Clark My Mahoney, PhD, Co-Chair David J. Margolis, MD/PhD John R. Stanley Thomas N. Darling Sarah Millar, PhD Anthony E. Oro, MD/PhD Robert Swerlick Jeffrey M. Davidson Paulk Nghiem, MD/PhD M. Joyce Rico, MD/MBA Jouni Uitto Mitchell F. Denning Abrar Qureshi, MD/MPH John Seykora, MD/PhD Hywel Williams Richard L. Eckert Alice Pentland, MD, ex officio Martin Weinstock, MD/PhD Stuart Yuspa James T. Elder Nicole Ward, PhD Alexander H. Enk, Victoria Werth, MD Resident/Post-Doctoral Statistical Editor Kenneth Feingold Robyn Cipolletti, Staff Liaison Beverley Adams-Huet David E. Fisher Jim Rumsey, Staff Liaison Fellows Fang Liu, PhD Gary J. Fisher Lisa Liu, MD/PhD JID Connector Editor Carsten Flohr Ad Hoc Reviewers Kavitha Reddy Richard Gallo John Harris, MD/PhD Luis A. Garza SID Administrative Staff Kiyoshi Ariizumi, PhD JID Jottings Editor Spiro Getsios Jim Rumsey Xiao-Jing Wang, MD/PhD Lowell A. Goldsmith Michel F. Gilliet Executive Director, Stephen Tyring, MD/PhD Michael Girardi Chief Operating Officer Joel Gelfand, MD Cells to Surgery Quiz Editor Matthias Goebeler Maria I. Morasso, PhD Keyvan Nouri Kathleen J. Green Rebecca Minnillo, DM/MPA Mei Chen, PhD Alain Hovnanian Executive Director, Eli Sprecher, MD/PhD Meet the Investigator Editor Alan D. Irvine Chief Program and James K. Wahl, III, PhD Pooja Chitgopeker Rivkah lsseroff Development Officer Anna Di Nardo, MD/PhD Kenji Kabashima Jeffery Travers, MD/PhD Meeting Reports Editor Veli-Matti Kiihiiri Maria Asher Brian Pollack, MD/PhD GeraldS. Lazarus Sarolta K. Karpati Manager, Program Services Valentina Greco, PhD Kenneth A. Katz Vladimir Botchkarev, MD/PhD Milestones Editor Tatsuyoshi Kawamura Robyn Cipolletti Michael Rosenblum, MD/PhD Hensin Tsao Reinhard Kirnbauer Director, Association Services Jan Dutz, MD Andrew P. Kowalczyk Kenneth Tsai, MD/PhD Podcast Editor Thomas Krieg Rachel Cobb Sewon Kang, MD Robert Dellavalle Molly Kulesz-Martin Meetings Support Robert Kirsner, MD/PhD Martin Leverkus Terry Lechler, PhD Research Techniques Made Simple David Margolis Stephanie Flanagan M. Joyce Rico, PhD Kathryn Schwarzcnberger (Editor) Alain Mauviel Manager, Member Services Amy Paller, MD Arlene Ruiz de Luzuriaga Akimichi Morita C. Michael DiPersio, PhD (Associate Editor) Paul Nghiem Deborah Kovacs Lloyd Miller, MD/PhD Manabu Ohyama Manager, Association Services Santosh Katiyar, PhD Visual Ox Quiz Editor Amy S. Paller Andrej T Slominski, MD/PhD Robert S. Kirsner, Miami, FL Andrey A. Panteleyev Bruce Morgan, PhD JID Staff Vincent Piguet Marie Tuttle, MD Elizabeth Nelson Blalock Medical Writer Carlo Pincelli Managing Editor, JID Heather Yarnall Schultz Dennis Roop Sarbjit S. Saini Governance Sarah Forgeng Editors Emeriti Fernanda Sakamoto Officers and Directors JID Editorial Office Assistant Marion B. Sulzberger, 1938-1949 Yardena Samuels S. Wright Caughman, MD Naomi M. Kanof, 1949-1967 Helmut Schaider President Journal Editorial Board Richard B. Stoughton, 1967-1972 Christoph Schlapbach Irwin M. Freedberg, 1972-1977 Martin Schmelz Alexa Kimball, MD/MPH Editor Ruth K. Freinkel, 1977-1982 Jochen Schmitt Vice President Barbara A. Gilchrest Howard P. Baden, 1982--1 987 Glynis Scott David A. Norris, 1 987-1992 Julia A. Segre Mark Udey, MD/PhD Advisory Board Edward J. O’Keefe, 1992-1997 John Seykoril President-Elect Paul R. Bergstresser Conrad Hauser, 1997-2002 Jan C. Simon Lowell A. Goldsmith Lowell A. Goldsmith, 2002-2007 Eli Sprecher Anthony Gaspari, MD Erwin Tschachler Paul R. Bergstresser, 2007-2012 Richard Spritz Vice President-Elect Phyllis I. Spuls Deputy Editors Alice Pentland, MD Angela M. Christiano Secretary-Treasurer Thomas Werfel

125 SID Governance

Robert S. Stern Committee on Membership Y. Mishima 1997 Stephen Katz John P. Sundberg Maryam Asgari, MD/MPH, Chair T. Nishikawa 1998 Klaus Wolff Marjana Tomic-Canic Richard Gallo, MD/PhD, ex-officio D. Norris 1999 lowell Goldsmith Sergey M. Troyanovsky Lloyd Miller, MD/PhD S. Ofuji 2000 Richard Dobson Mark C. Udey 2001 Robert Briggaman Maurice van Steensel George Sen, PhD H. Ogawa Baoxi Wang Becky Minnillo, DM/MPA, S. Pinnell 2002 Eugene Bauer Xiao-JingWang Staff Liaison M. Prunieras 2003 Georg Stingl Nicole L Ward W. Quevedo, Jr. 2004 Stuart Yuspa Wendy Weinberg Committee on Nominations H. Rorsman 2005 John Voorhees Traci Wilgus Kathleen Green, PhD, Chair W. Shelley 2006 thomas Lawley Giovanna Zambruno Thomas Kupper, MD B. Shroot 2007 Barbara Gilchrest Xuejun Zhilng Detlef Zillikens Kim Yancey, MD S. Shuster 2009 luis Diaz Becky Minnillo, DM/MPA, F. Snyder 2010 Dennis Roop Staff Liaison D. Stevanovic 2011 John Stanley Standing Committees G. Stingl 2012 Paul Bergstresser Honorary Members J. Strauss 2014 Jouni Uitto Auditing Committee H. Baden H. Tagami Lynn Cornelius, MD, E. Bauer N. Thyresson Naomi M. Kanof Clinical Anthony Gaspari, MD P. Bergstresser J. Uitto Investigator Award Alexa Kimball, MD/MPH, Chair E. Beutner E. Van Scott This award is given to enlighten Brian Poligone, MD/PhD D. Bickers J. Voorhees present and future workers about Martin Weinstock, MD/PhD O. Braun-Falco P. Weary the importance of clinical Jim Rumsey, Staff Liaison I. Braverman G. Weinstein investigation. It honors an A. Breatnach C. Wheeler, Jr. individual who has made signifi- Committee on Education R. A. Briggaman K. Wolff cant contributions to our under- Suephy Chen, MD, Co-Chair W. Bullough K. L. Yang standing of clinical medicine. Anthony Gaspari, MD, ex-officio H. D. Chen 1993 Alvan Feinstein Douglas Grossman, MD/PhD L. H. Chiung SID Awards 1994 R.Michael Blaese Valerie Horsley, PhD E. Christophers Stephen Rothman Memorial 1995 Judah Folkman Youn Kim, MD R. Degos Award Recipients 1996 Jean Wilson Alexa Kimball, MD/MPH, L. Diaz Presented for distinguished 1997 C. Garrison Fathman ex-officio R. Dobson service to investigative cutaneous 1998 Jeffrey Bluestone Fang Liu, PhD, ex-officio R. Eady medicine. 1999 Brian Strom Lisa Liu, MD/PhD, ex-officio A. Eisen 1967 Marion Sulzberger 2000 William Kelley Maria Morasso, PhD A. ElMofty 1968 Donald Pillsbury 2001 James Ostell Alan Moshell, MD, Co-Chair E. Epstein 1969 Harvey Blank 2002 leena Peltonen Kavitha Reddy, MD J. Fernandez 1970 thomas Fitzpatrick 2003 Judith Campisi John Seykora, MD/PhD I. Freedberg 1971 Aaron Lerner 2004 Brian Druker Becky Minnillo, DM/MPA, R. Freinkel 1972 William Montagna 2005 Joseph Nadeau Staff Liaison B. Gilchrest 1973 Rudolf Baer 2006 John Schiller I. Gigli 1974 Hermann Pinkus 2007 thomas Pearson Executive Committee L. Goldsmith 1975 Eugene Van Scott 2009 Mahlon DeLong Paul Bergstresser, MD R. Goltz 1976 Albert Kligman 2010 Douglas Lowy S. Wright Caughman, MD M. Greaves 1977 irvin Blank 2011 David Lane Richard Gallo, MD/PhD H. Green 1978 George Odland 2012 luis Parada Barbara Gilchrest, MD J. Grupenhoff 1979 Clayton Wheeler, Jr. 2014 Mark Chance Anthony Oro, MD/PhD G. Hambrick, Jr. 1980 Clarence Livingood Alice Pentland, MD J. Hanifan 1981 isadore Bernstein Mark Udey, MD/PhD F. Hu 1982 J. Lamar Callaway Jim Rumsey, ex officio Y. Ishibashi 1983 Richard Stoughton Becky Minnillo, DM/MPA, S. Jablonska 1984 A Gedeon Matoltsy ex officio R. Jordon 1985 Herman Beerman S. Katz 1986 otto Braun-Falco Committee on Finances A. Kligman 1987 Walter Shelley Janet Fairley, MD, Chair K. Kraemer 1988 John Strauss Richard Gallo, MD/PhD, ex-officio G. Krueger 1989 Walter Lobitz, Jr. Barbara Gilchrest, MD, ex-officio A. Kukita 1990 Walter Lever David Margolis, MD/PhD C. Lapière 1991 Robert Goltz Aimee Payne, MD/PhD G. Lazarus 1992 irwin Freedberg Alice Pentland, MD, ex-officio A. Lerner 1993 Arthur Eisen Thomas Ruenger, MD/PhD J. Leyden 1994 Ruth Freinkel Jeffrey Travers, MD/PhD W. Lobitz, Jr. 1995 Howard Baden Jim Rumsey, Staff Liaison I. Magnus 1996 irma Gigli

126 SID Governance

Julius Stone Lectureship 2000 thomas Luger 1994 Solomon Snyder Albert M. Kligman / Phillip This award is intended to promote 2001 Peter Elias 1995 Eric Lander Frost Leadership Lecture & the advancement of knowledge 2002 Kathleen Green 1996 irving Weissman Award in immunology as it relates to the 2003 Masayuki Amagai 1997 Michael Karin This award is made to an individu- skin and skin disease. 2004 Akira Takashima 1998 Günter Blobel al in acknowledgment of signifi- 1999 Eli Gilboa 2005 Paul Khavari 1999 Philippa Marrack cant contributions to the under- 1999 Stephen Johnston 2006 Richard Gallo 2000 Robert Langer standing of structure and function 1999 Jeffrey Trent 2007 George Cotsarelis 2001 William Haseltine of skin in the past five years. 2000 nigel Bunnett 2008 Pierre Coulombe 2002 Ronald DePinho 2008 Jouni Uitto 2000 Ronald Crystal 2009 Angela Christiano 2003 thomas Jessell 2009 Stephen Katz 2000 Ralph Steinman 2010 W. H. Irwin McLean 2004 Robert Weinberg 2010 John R. Stanley 2001 Roland Martin 2011 John McGrath 2005 timothy Ley 2011 Peter Elias 2002 Gerald Crabtree 2012 Howard Chang 2006 Amita Sehgal 2012 Robert Lavker 2004 Adrian Hayday 2013 Andrzej Dlugosz 2007 Stuart Schreiber 2013 Elaine Fuchs 2005 Polly Matzinger 2014 Xiao-Jing Wang 2009 Daniel Kastner 2014 Robert Modlin 2006 Alexander Rudensky 2010 Raymond Schinazi 2007 Donald Y.M. Leung Herman Beerman 2011 Jennifer Lippincot- SID/Galderma Acne 2009 Jamey Marth Lectureship Schwartz Research Award 2012 Mina Bissell 2010 Rafi Ahmed This lecture is given by a 2002 Diane Thiboutot 2013 Allan Balmain 2011 Casey Weaver distinguished medical scholar, 2003 Jenny Kim 2014 Hopi Hoekstra 2012 Rebecca Buckley traditionally from fields other 2004 Michaela Downie 2014 Alice P. Pentland than dermatology. 2005 Andrzej Dlugosz 1961 Rene Dubos Eugene M. Farber Psoriasis 2006 Sewon Kang William Montagna 1962 Hans Selye Research Award 2007 Philip Liu Lectureship 1963 Rupert Billingham This award is presented at the This annual award is intended to 1964 Curt Stern Annual Meeting to young SID/Galderma Rosacea honor and reward young active 1965 Albert Szent-Gyorgyi investigators whose focus is Research Award 1966 Jerome Gross on psoriasis research. investigators. Primary emphasis 2009 Kenshi Yamasaki is given to researchers in skin 1967 G.J.V. Nossal 2003 David Jones 1968 John Buettner-Janusch thomas McCormick biology. 1975 Kenneth Halprin 1969 Henry Kunkel 2004 Edmund Lee 1976 Frank Parker 1970 norman Wessells Michael Allen 1977 Arthur Eisen 1971 Aiden Breathnach 2005 Curdin Conrad 1978 irma Gigli 1972 Frank Dixon Shigetoshi Sano 1979 Marvin Karasek 1973 H. Hugh Fudenberg 2006 Helen Young 1980 irwin Freedberg 1974 Charles Cochrane Amos Gilhar 1981 Stephen Katz 1975 David Katz 2007 Rajan Nair 1982 John Parrish 1976 Bert O’Malley 1983 Douglas Lowy 1977 Russell Ross Eugene M. Farber 1984 Gerald Lazarus 1978 Hilary Koprowski Lectureship 1985 Eugene Bauer 1979 Michael Brown This lecture is presented by an 1986 Georg Stingl 1980 Phil Leder investigator whose work is relevant 1987 Jouni Uitto 1981 Pedro Cuatrecasas to expanding our insights into the 1988 Stuart Yuspa 1982 Frank Ruddle pathophysiology and treatment of 1989 tung-Tien Sun 1983 lawrence Lichtenstein psoriasis. 1990 Karen Holbrook 1984 Robert Gallo 2007 Brian Nickoloff 1991 luis Diaz 1985 thomas Waldmann 2008 Enno Christophers 1992 Dennis Roop 1986 torsten Wiesel 2009 James T. Elder 1993 Ervin Epstein, Jr. 1987 leroy Hood 2010 James Krueger 1994 John Stanley 1988 Joseph Goldstein 2011 Kevin Cooper 1995 Elaine Fuchs 1989 Pierre Chambon 2012 Frank Nestle 1996 thomas Kupper 1990 Ronald Herberman 2014 Joel Gelfand 1997 Barbara Gilchrest 1991 K. Frank Austen 1998 Robert Modlin 1992 Bert Vogelstein 1999 Fiona Watt 1993 Charles Janeway, Jr.

127 NOTES

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The Westin Kierland Resort & Spa

Society for investigative dermatology 75 th annual meeting Scottsdale, arizona MAY 11-14, 2016