NEURL2 Antibody Cat. No.: 30-830

NEURL2 Antibody

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region IMMUNOGEN: of human NEURL2.

TESTED APPLICATIONS: ELISA, WB

NEURL2 antibody can be used for detection of NEURL2 by ELISA at 1:312500. NEURL2 APPLICATIONS: antibody can be used for detection of NEURL2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

POSITIVE CONTROL: 1) Cat. No. XBL-10413 - Fetal Skeletal Muscle Tissue Lysate

PREDICTED MOLECULAR 32 kDa WEIGHT:

Properties

PURIFICATION: Antibody is purified by peptide affinity chromatography method.

CLONALITY: Polyclonal

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

September 28, 2021 1 https://www.prosci-inc.com/neurl2-antibody-30-830.html Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% BUFFER: sucrose.

CONCENTRATION: batch dependent

For short periods of storage (days) store at 4˚C. For longer periods of storage, store STORAGE CONDITIONS: NEURL2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Additional Info

OFFICIAL SYMBOL: NEURL2

ALTERNATE NAMES: NEURL2, C20orf163, MGC125934, MGC125935, OZZ, Ozz-E3, OZZ-E3

ACCESSION NO.: NP_542787

PROTEIN GI NO.: 18152787

GENE ID: 140825

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

NEURL2 contains 1 NHR (neuralized homology repeat) domain and 1 SOCS box domain. NEURL2 plays an important role in the process of myofiber differentiation and maturation. NEURL2 is the probable substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex, which BACKGROUND: mediates the ubiquitination of proteins. NEURL2 probably contributes to catalysis through recognition and positioning of the substrate and the ubiquitin-conjugating enzyme. During myogenesis, it controls the ubiquitination and degradation of the specific pool of CTNNB1/beta-catenin located at the sarcolemma.

REFERENCES: 1) Song, R., (2006) J. Biol. Chem. 281 (47), 36391-36400.

ANTIBODIES FOR RESEARCH USE ONLY.

For additional information, visit ProSci's Terms & Conditions Page.

September 28, 2021 2 https://www.prosci-inc.com/neurl2-antibody-30-830.html