Ann Arbor SPARK Sector Report Life Sciences

http://annarborusa.org/

Ann Arbor SPARK will advance the economy of the Ann Arbor region by establishing the area as a desired place for business expansion and location... by identifying and meeting the needs of business at every stage, from those that are established to those working to successfully commercialize innovations. 2 Ann Arbor SPARK 201 S. Division, Suite 430, Ann Arbor, Michigan 48104 T:734-761-9317 F:734-761-9062 annarborusa.org

Ann Arbor, Michigan

Ann Arbor’s life sciences sector has seen rapid growth over the past decade, but we’ve always been an innovator in the biotech industry. The heart-lung machine used in the first heart transplant was developed and manufactured here. Since then, the life sciences sector has expanded to include pharmaceuticals, medical devices, diagnostics, and bioinformatics. The sector includes 250+ firms and employs more than 6,000 people in the region.

Population Education Level: Washtenaw County

367,627 Washtenaw County 53.2% Bachelor’s Degree or Higher 118,087 Ann Arbor City 30.2% United States 1,109,000 Within a 30 mile commute Rankings

Median Age #1 Top 100 Best Places to Live, 2018 Best College Towns & Cities, 2018 33.4 Washtenaw County #1 Best Cities to Live, 2018 27.5 Ann Arbor City #1 39.5 Michigan #4 Best Cities to Raise a Family, 2018 37.6 US #1 Most Educated Cities, 2017 #7 Best Cities for Entrepreneurs, 2017 Median Household Income #1 Best College Cities, 2017 $62,484 Washtenaw County

Source: US Census and https://annarborusa.org/insights/communities/facts-rankings/

The Midwest is becoming a national center for the life sciences industry. And at the heart of it all is Ann Arbor, where business intersects with advanced research, out- of-the-box thinkers, abundant financial resources, a vibrant economic development initiative and an immense talent pool. Ann Arbor SPARK 201 S. Division, Suite 430, Ann Arbor, Michigan 48104 T:734-761-9317 F:734-761-9062 annarborusa.org 3

Ann Arbor Business Community Profile In addition to many established industries, the area has become a magnet for emerging and rapidly growing sectors such as: Automotive R&D and Engineering, Software, Life Sciences, and Data & Information. TOP 25 REGIONAL EMPLOYERS (JAN 2019)

COMPANY NAME BUSINESS DESCRIPTION EMPLOYEES Public University and Health System 33,225 Trinity Health Health Care System 7,435 General Motors Milford Proving Grounds OEM research 5,500 Public School 2,225 Faurecia North America Automotive Component Mfg. 1,664 Eastern Michigan University Public University 1,559 Integrated Health Associates (IHA) Medical Center 1,442 Thomson Reuters Software/IT 1,300 Washtenaw County Government 1,264 Terumo Cardiovascular Group Surgical & Medical instruments, 1,100 Cardiovascular Toyota Technical Center, York Township OEM Research 1,095 St Joseph Mercy Chelsea Medical Center 1,082 Domino's Pizza Headquarters 865 IBM Watson Health Data and Information 850 Thai Summit American Corporation Automotive Component Mfg 816 Grupo Antolin Interiors Automotive Component Mfg 800 City of Ann Arbor Government 712

Ford Motor Company Automotive Component Mfg 700 Zingerman's Family of Businesses Food Production 700 NSF International Testing, Inspection, & Certification 693 Citizens Insurance Insurance Services 600 Truck Hero Automotive Component Mfg 600 Washtenaw Community College Public Education 597 JAC Products Automotive Component Mfg. 575 Toyota Technical Center, Ann Arbor OEM research 566 Tribar Manufacturing Automotive Component Mfg 550 4 Ann Arbor SPARK 201 S. Division, Suite 430, Ann Arbor, Michigan 48104 T:734-761-9317 F:734-761-9062 annarborusa.org

Regional Life Science Companies

Ann Arbor Life Sciences Industry Sector Approximately 280 life sciences firms are located in the Ann Arbor region. The largest sectors are those related to medical device manufacture and pharmaceutical development. Service providers, including CROs, software development, and prototyping, are found in the Ann Arbor area. The University of Michigan’s Medical Innovation Center and Eastern Michigan University’s Coatings Research Institute also partner with life science firms to develop innovative solutions. SAMPLE OF ANN ARBOR LIFE SCIENCE COMPANIES COMPANY NAME BUSINESS DESCRIPTION EMPLOYEES Altarum Institute Health systems research 125 Avomeen Analytical Services Custom chemical analysis 45 Cayman Chemical Company Research products – Biomedical 225 Compendia Bioscience, Inc Bioinformatics 25 DNA Software, Inc. Bioinformatics – Computational biology 7 Enzo Life Sciences Research products – preclinical 57 development Essen BioScience Instrumentation 60 FlexDex Inc. Minimally invasive surgical tools 10 Gene Codes Corp. Bioinformatics – DNA sequence software 20 inVentiv Health Clinical Clinical research and testing 150 Koppert Biological crop protection and natural 36 pollination Mi Bioresearch CRO 43 NuStep Medical device manufacture 97 Rubicon Genomics Genome DNA manipulation and analysis 38 SurgiTel Precision optics - surgical, dental 55 Swift BioSciences Inc Genetic test kits for biological reasearch 19 Terumo Cardiovascular Group Medical device manufacture 1,100 Truven Health Analytics (IBM Watson Data and information 850 Health) Vericel Corporation Unique cell therapies and specialty biologics 58 Warde Medical Laboratory Biomedical reference testing 141 Xoran Technologies Medical imaging technology 54 Zomedica Pharmaceuticals Inc. Animal health solutions 8 Ann Arbor SPARK 201 S. Division, Suite 430, Ann Arbor, Michigan 48104 T:734-761-9317 F:734-761-9062 annarborusa.org 5

An Educational Powerhouse

Ann Arbor’s life sciences community benefits from University of Michigan regional colleges and universities, foremost of which is Research Spending the University of Michigan.

University of Michigan The University of Michigan ranks among the world’s $1.4 billion top universities and its graduate and professional #2 in the nation programs are consistently listed among the nation’s top ten.

The University houses a large number of research institutes: Life Sciences Institute Kellogg Eye Center Biomechanics Research Laboratory Biomedical Research Core Facility University Graduates

In addition, the North Campus Research Institute University Number and the Medical School are centers of life science of Michigan research. Graduates Total graduates 13,858 Eastern Michigan University The College of Technology at Eastern Michigan Biomedical engineering 175 University, located in downtown Ypsilanti, offers four Biomolecular science 141 year degrees in areas of biology and clinical research.

Regional Universities In addition to University of Michigan and Eastern Eastern Michigan Number Michigan University, Ann Arbor area employers can University recruit from universities within an hour’s drive of Graduates Ann Arbor—Wayne State University, Lawrence Tech, Total graduates 4,542 Kettering, and Michigan State University. All four have CAE/CAD 24 degree programs in life science-related disciplines. ME Technician 13

Washtenaw University of Michigan Ranks Community College 12,327 as the #1 Public Research Enrollment University in the US. Source: National Science Foundation 6 Ann Arbor SPARK 201 S. Division, Suite 430, Ann Arbor, Michigan 48104 T:734-761-9317 F:734-761-9062 annarborusa.org

University Graduate Retention Rates

40% of UM Alumni live 35% in Michigan of UM College of Engineering Grads Represents over 200,000 graduates remain in MI Up from 24% in 2010 and growing

50% of MSU Business School grads stay in MI 72% Represents 37,500 of Eastern Michigan graduates University Alumni remain in MI Represents 118,000 graduates Ann Arbor SPARK 201 S. Division, Suite 430, Ann Arbor, Michigan 48104 T:734-761-9317 F:734-761-9062 annarborusa.org 7

Talent

Talent acquisition and training is the top factor in a successful business.

SPARK partners with the University of Michigan, Eastern Michigan University, Michigan Works!, and other resources to help identify and recruit staff.

Some examples of how SPARK helps your talent needs: 8 Ann Arbor SPARK 201 S. Division, Suite 430, Ann Arbor, Michigan 48104 T:734-761-9317 F:734-761-9062 annarborusa.org

Training Grants: SPARK will work becoming a “job manager” here. closely with you to maximize utilization of worker training MHacks Sponsorship programs and funds that are MHacks, the largest student-run available for companies in our hackathon in the world, brings region. together the smartest people from all over for 36 hours of incredible Targeted Job Mixers/Open hacking. MHacks is the gateway Houses: Job mixers hosted by the between a company and top tech company are targeted to the exact talent and allows participating positions the firm is seeking. companies to network, promote brand awareness, get feedback on Ann Arbor Tech Homecoming: a product or API, and connect with On the Wednesday before talent. Thanksgiving, job seekers and companies mingle over delicious Eastern Michigan University food and great conversation. Digital Divas A great opportunity in a casual EMU’s College of Technology setting for local and out-of-town hosts a yearly conference that talent to learn about careers in the connects young women in middle vibrant Ann Arbor tech ecosystem. and high school to opportunities in These fast-growing, innovative STEM. The conference draws 500 companies have produced attendees and provides them with hundreds of jobs and billions in an introduction to tech careers enterprise value in the last 5 years. and the opportunity to meet and network with professors and The SPARK Talent Portal: students. A free online job posting system that spotlights executive and Girl Develop It knowledge-based positions as Girl Develop It empowers and well as internships and entry level assists women interested in positions. In 2016, the SPARK Job getting into and advancing in the portal had over 1,200 jobs posted, tech industry by offering courses over 106K views and nearly 1,000 focused on modern development resumes submitted. Employers best practices and a real world can view resumes submitted by outcomes.

Resumes posted on SPARK Job Portal in 2018 Above: Logos for MHacks and Girl Develop It. Previous Page: 500+ Tech Homecoming 2017. Ann Arbor SPARK 201 S. Division, Suite 430, Ann Arbor, Michigan 48104 T:734-761-9317 F:734-761-9062 annarborusa.org 9

International Airport Connectivity

Detroit Metropolitan Airport (DTW) is less than 30 miles from downtown Ann Arbor (29 minutes by car). DTW is ranked #11 nationally and is a major Delta hub. There are nearly 20 million annual business passengers and nearly 3 million annual international passengers flying out of DTW.

# of daily non-stop flights from Sample of National and International Destinations DTW Atlanta (ATL) 16 Chicago (MDW and ORD) 32 Dallas (DAL and DFW) 14 Los Angeles (LAX) (+1 flight per day to SNA) 8 Mexico City (MEX) 2 New York (JFK, LGA, and EWR) 38 Sao Paolo (GRU) 1 San Francisco (SFO) 6 Seattle (SEA) 6 Tampa (TPA) 3

Map of non-stop flights from Detroit Metro Primary international destinations are Amsterdam, Frankfort, London, Toronto, and Tokyo. 10 Ann Arbor SPARK 201 S. Division, Suite 430, Ann Arbor, Michigan 48104 T:734-761-9317 F:734-761-9062 annarborusa.org

Workforce and Location

LIFE SCIENCES WORKFORCE The Ann Arbor labor market extends into the adjacent Detroit/Livonia/Dearborn MSA, providing a labor pool of 1,109,000 within a 30-minute commute of Ann Arbor. Detroit/Livonia/ Total both Job Title Ann Arbor MSA Dearborn MSA MSAs Medical Scientists 900 NA 900 Chemists 390 420 810 Biological Scientists 160 NA 160 Software Developers 3,010 7,710 10,720 Mechanical Engineers 1,060 11,140 12,200 Biological Technicians 420 90 510 Chemical Technicians 160 190 350 Source: BLS, May 2017 Ann Arbor SPARK 201 S. Division, Suite 430, Ann Arbor, Michigan 48104 T:734-761-9317 F:734-761-9062 annarborusa.org 11

Employee Location Life sciences company located in Ann Arbor, MI employs Our workforcemore than 1,000 is people mobile living in Washtenaw County and throughout the region.

A surgical and medical instruments company located in Ann Arbor employs more than 1,200 people living in Washtenaw County and throughout Michigan and surrounding states. Southeast Michiganders are accustomed to commuting long distances for work (and often, telecommutingHighest Concentration of Life as Science well). Employees to Lowest 12 Ann Arbor SPARK 201 S. Division, Suite 430, Ann Arbor, Michigan 48104 T:734-761-9317 F:734-761-9062 annarborusa.org

Local Life Sciences Cluster

The Ann Arbor region contains a large Life Sciences industry that represents over 6,000 employees. Of all the life science companies based in the area, Integrated Health Associates provides the largest employee base accounting for over 20% of the area’s industry. While IHA falls into the Healthcare services sub-sector, the region has a particularly large presence of Medical Device companies. The Medical Device sub-sector accounts for nearly 40% of the industry’s FTE jobs with Terumo Cardiovascular Group claiming a total of 1,100 FTE. Aside from Medical Devices and Healthcare services the region is also home to a vast array of Pharmaceutical, Digital Health, and Biotechnology companies. Ann Arbor SPARK 201 S. Division, Suite 430, Ann Arbor, Michigan 48104 T:734-761-9317 F:734-761-9062 annarborusa.org 13

Community Engagement LOCAL LIFE SCIENCES COMMUNITY NETWORKING AND EVENTS

The local life sciences community and universities have hosted a number of groups, hackathons and conferences for the further development of skills and connections. A few examples are below: MichBio The state-level membership organization for bio-industries. Their mission encompasses broad industry sub-sector representation including pharmaceuticals and therapeutics (human and animal health, generics and OTCs), medical

BioArbor access to resources, and creating community. Five The life sciences forum. http://www.michbio. presenters this month take the stage for ten minutes org/?page=bioarborevents each, five minutes to demo and five minutes to answer questions, followed by open announcements and com- Meetups munity networking. E-mail organizers at a2newtech. The meetup culture in Ann Arbor is open and org if you’d like to present! flourishing. A selection of meetups is below, Ann Arbor Security Meetup please visit http://madeina2.com/community/ Coffee House Coders for a full list of coder groups, maker groups, Girl Develop It un/conferences, hackathons, and more in our Michigan Devs community. A2 Mobility Tech Ann Arbor FinTech Meetup a2geeks Duo Tech Talks Nonprofit organization dedicated to making Ann Arbor All Hands Active a great place for creative and innovative people to live and work by opening the tech culture to everyone. A2Geeks is a nonprofit dedicated to making southeast Michigan and Ann Arbor in particular, a great place for geeks and creatives to live, work, and play. We support individuals and groups seeking to build community around issues or projects they are passionate about and to educate others in the area.

A2NewTech Ann Arbor New Tech seeks to foster tech entrepre- neurship by facilitating communication, providing 14 Ann Arbor SPARK 201 S. Division, Suite 430, Ann Arbor, Michigan 48104 T:734-761-9317 F:734-761-9062 annarborusa.org

Destination Ann Arbor

Every community offers something unique to its residents, but the Ann Arbor area offers much more than the usual quality of life indicators. From recreation to culture, we offer large city amenities with a small town feel. Read on to learn more about living here.

Recreation In Michigan, you’re never more than a few miles from water. In Washtenaw County, we can top that by saying you’re never more than a few miles from a lake, river, park, golf course, cross-country trail, or other recreational option.

Washtenaw County boasts 4,000 acres of parkland, of which 2200 acres are natural areas ideal for hiking, bird watching, or mountain biking. The Border-to- Border trail, kayaking liveries, and golf courses add to the county’s recreation inventory.

The city of Ann Arbor has 157 parks totaling 2,090 acres, 1,200 acres of which are natural areas. An additional 2,000 acres of farmland and open space surround the city of Ann Arbor, purchased with a Greenbelt millage.

Ann Arbor parks offer baseball and softball diamonds and leagues, soccer fields, disc golf, ice skating, and an excellent skateboard park.

Housing County residents can find multiple housing options and locations: cities, towns, country, and suburban. Housing options include single family houses, downtown lofts, condos, and apartments. Housing costs in Washtenaw County are lower than east and west coast housing: The median sale price of single family house in Washtenaw County is $279,700 (source: Zillow).

Schools Public, charter, and private schools are found in Washtenaw County. A list of recent test scores by school and district is found here, MEAP scores here. Ann Arbor SPARK 201 S. Division, Suite 430, Ann Arbor, Michigan 48104 T:734-761-9317 F:734-761-9062 annarborusa.org 15

Culture The University Musical Society brings national and Rankings international cultural performances to Ann Arbor (the New York Philharmonic has an annual residency in Ann 2018 Arbor). Our local cultural venues include the Ann Arbor “Top 100 Best Places Symphony Orchestra, the Ann Arbor Civic Theater, to Live” - Ann Arbor, the Ark, and the Purple Rose Theater, along with #1 Livability independent dance and music performance staged in the historic Michigan Theater. “Best College Towns & Cities in America” - Ann Fun #1 Arbor, WalletHub.com The Ann Arbor area isn’t all high-brow. Here is a smattering of the festivals and activities that take place “Best Cities to Raise a throughout the county. Family” – Ann Arbor, Ann Arbor FestiFools #4 Niche.com Ann Arbor Summer Festival Ann Arbor’s Rolling Sculpture Car Show Chelsea’s Sounds & Sights Festival Dexter Daze 2017 Manchester Chicken Broil Manchester’s Riverfolk Music and Arts “Best College Cities” - Milan Bluegrass Festival Ann Arbor, Aier Milan Fliers model aircraft flights #1 Saline Celtic Festival “Best Cities to Live in Ypsilanti’s Summer Beer Festival America” - Ann Arbor, Ypsilanti Heritage Festival #1 Niche “Top 100 Best Places Shopping to Live” - Ann Arbor, You’ll find independent retailers, wine shops, bakeries #3 Livability and delis in the downtowns. “Best Colleges For Your Local grocery stores - People’s Food Co-op, Arbor Money” - University of Farms, By the Pound, Monahan’s Seafood Market, #3 Michigan, Time.com Zingerman’s Bakery and Creamery. You’ll also enjoy farmers’ markets, cider mills, you-pick berry and apple “Best Cities for farms, and CSAs. Entrepreneurs” - Ann #7 Arbor, Livability.com Regular grocery stores - Whole Foods, Trader Joe’s, “Best Cities for Small Busch’s, Meijer, Kroger. Business” - Ann Arbor, Valuepenguin.com Clothing, sporting goods, sundries – Local clothing stores #9 and gift shops are found in downtowns. Arborland, “The Top 15 Universities , and big box stores offer brand name Producing Unicorn shopping. #9 Founders” - University of Michigan, Tech.co 16 Ann Arbor SPARK 201 S. Division, Suite 430, Ann Arbor, Michigan 48104 T:734-761-9317 F:734-761-9062 annarborusa.org

Contact details:

Phil Santer, SVP of Business Development, Chief of Staff [email protected] 734-527-9176

http://annarborusa.org/

Ann Arbor SPARK will advance the economy of the Ann Arbor region by establishing the area as a desired place for business expansion and location... by identifying and meeting the needs of business at every stage, from those that are established to those working to successfully commercialize innovations.