DOCSLIB.ORG

Methylation and Exposure Biomarkers of the Hebei Spirit Oil Spill Cohort in Taean, Korea*

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Methylation and Exposure Biomarkers of the Hebei Spirit Oil Spill Cohort in Taean, Korea* Environmental Pollution 263 (2020) 114607 Contents lists available at ScienceDirect Environmental Pollution journal homepage: www.elsevier.com/locate/envpol Cross-sectional and longitudinal associations between global DNA (hydroxy) methylation and exposure biomarkers of the Hebei Spirit oil spill cohort in Taean, Korea* Nivedita Chatterjee a, Jaeseong Jeong a, Myung-Sook Park b, Mina Ha c, * Hae-Kwan Cheong d, Jinhee Choi a, a School of Environmental Engineering, University of Seoul, 163 Seoulsiripdae-ro, Dongdaemun-gu, Seoul, 02504, South Korea b Taean Environmental Health Center, Taean, Chungnam, 32148, South Korea c Department of Preventive Medicine, Dankook University College of Medicine, Cheonan, Chungnam, 31116, South Korea d Department of Social and Preventive Medicine, Sungkyunkwan University School of Medicine, Suwon, Gyeonggi, 16419, South Korea article info abstract Article history: The Hebei Spirit oil spill (HSOS) occurred on the west coast of South Korea (Taean county) on December Received 8 October 2019 7, 2007, and studies revealed that exposure to the oil spill was associated with various adverse health Received in revised form issues in the inhabiting population. However, no studies evaluated the association between crude-oil 25 March 2020 exposure and epigenetic changes. This study aimed to investigate the HSOS exposure-associated longi- Accepted 14 April 2020 tudinal and cross-sectional variations in global DNA methylation (5-mc) and/or hydroxymethylation (5- Available online 18 April 2020 hmc) and expression profiles of related genes in Taean cohort participants from 2009 (AH-baseline) and 2014 (AH-follow-up) relative to the reference group (AL). We measured global DNA 5-mc and 5-hmc Keywords: fi fi Hebei Spirit oil spill adult cohort levels and related gene expression levels in whole blood. We identi ed signi cant associations be- DNA methylation (5-mc) tween HSOS exposure and AH-baseline-5-mc, AH-baseline-5-hmc, and AH-follow-up-5-hmc. HSOS DNA hydroxymethylation (5-hmc) exposure was associated with lower %5-mc content and higher %5-hmc content in the same individuals DNMT3B from both the cross-sectional and longitudinal studies. In addition, we found a strong correlation be- TET1 tween 5-mc and DNMT3B expression, and between 5-hmc and TET1 expression. Our findings suggested that epigenetic changes are important biomarkers for HSOS exposure and that 5-hmc is likely to be more sensitive for environmental epidemiological studies. © 2020 Elsevier Ltd. All rights reserved. 1. Introduction City. Shortly after the accident, many volunteers, most of which were local residents with military personnel, participated in longer The Hebei Spirit oil spill (HSOS) occurred on the west coast of cleanup activities for periods ranging from days to several months South Korea (Taean county) on December 7, 2007 and was (Ha et al., 2012). During the early clean-up work, some of the par- considered not only one of the worst oil spills in Korea, but also one ticipants lacked protective equipment and were exposed to oil- of the most serious oil spills in the history of East Asia (Yim et al., related chemicals. Previous studies on the Taean cohort suggested 2012). The spill size was relatively small (estimated 10,900 tons adverse health effects, such as the increased levels of oxidative of crude oil) compared to those of other major oil spill accidents stress biomarkers (MDA and 8-OHdG) and PAH metabolites (1-OHP worldwide (e.g., the Exxon Valdez spilled 37,000 tons of crude oil) and 2-NAPH) in clean-up participants, which were found to be (Kim et al., 2017). However, the main concern regarding the HSOS correlated with the duration of clean-up work in a cross-sectional was that the accident occurred near a heavily populated area, only study (Eom et al., 2011; Ha et al., 2012; Kim et al., 2017; Noh about 10 km away from the beach and the residential area of Taean et al., 2015). In general, crude oil contains various substances, including volatile organic compounds (VOCs), polycyclic aromatic hydrocar- bons (PAHs), and heavy metals. The majority of the components * This paper has been recommended for acceptance by Christian Sonne. present in crude oil are classified under group 1 (carcinogenic), * Corresponding author. E-mail address: [email protected] (J. Choi). group 2A (probably carcinogenic), and group 2B (possibly https://doi.org/10.1016/j.envpol.2020.114607 0269-7491/© 2020 Elsevier Ltd. All rights reserved. 2 N. Chatterjee et al. / Environmental Pollution 263 (2020) 114607 carcinogenic) chemicals in International Agency for Research on participate clean-up work for AL group. Finally, 30 persons for AL Cancer (IARC) monograms (Choi et al., 2018; Park et al., 2017; Yang (AL-follow-up group) and 32 for AH (AH-baseline as well as AH- et al., 2017). follow-up groups) were included in the present study. The study The ‘induction of epigenetic alterations’ is one of ten key char- protocol was approved by the Institutional Review Board of Dan- acteristics of carcinogens described in IARC monographs 112 and kook University Hospital, and informed consent was obtained from 113 (Smith et al., 2016). An increasing number of studies reported a all subjects (IRB no. 0904-027, 2014-06-013). significant association between epigenetic biomarkers and disease. Alterations in epigenetic biomarkers, particularly global DNA 2.2. Questionnaire methylation levels, including 5-methylcytosine (5-mc) and 5- hydroxymethylcytosine (5-hmc) levels, and the expression levels Demographic information was obtained through self-reported of their regulatory genes are associated the incidence of various questionnaire each surveys. Socio-demographic factors, i.e., age at types of cancer (Fouad et al., 2018; Joyce et al., 2016; Li et al., 2017; the oil spill accident (<60, 60), gender (male, female), healthy Lian et al., 2012; Sarabi and Naghibalhossaini, 2015; Tucker et al., behavior, i.e., smoking status (never smoker, current smoker, ex- 2018; Wilson et al., 2007). smoker) were considered. Participants were asked about duration On the other hand, the epigenetic alterations showed a relation of participated cleanup-works. The distance from the oil spill site with various environmental and occupational exposure (Cardenas was calculated using the ArcGIS Desktop ver.9.3 geographic infor- et al., 2017, 2015; Martin and Fry, 2018; Sanchez-Guerra et al., mation system (ESRI, Redlands, CA, USA), based on the latitude and 2015; Tellez-Plaza et al., 2014) and the incidence of various types longitude of the residential address, and considered when selecting of cancer (Fouad et al., 2018; Joyce et al., 2016; Li et al., 2017; Lian the group. et al., 2012; Sarabi and Naghibalhossaini, 2015; Tucker et al., 2018; Wilson et al., 2007). Nonetheless, the association of 5-mc 2.3. Global DNA methylation (5-mc) and global DNA and 5-hmc levels with specific biological changes caused by envi- hydroxymethylation (5-hmc) measurements ronmental exposure has not been well explored in epidemiological studies, except for a few recent studies (Cardenas et al., 2017; Total DNA from whole blood samples were extracted using a Sanchez-Guerra et al., 2015; Tellez-Plaza et al., 2014). DNA extraction kit (NucleoSpin, Macherey-Nagel). DNA quality and No studies have investigated epigenetic changes, such as global quantity were evaluated using a micro-volume spectrophotometer DNA methylation levels following crude oil spill exposure, and their (ASP-2680, ACTGene, Piscataway, NJ, USA). Next, global DNA associations with biomarkers for exposure or health effects. methylation [MethylFlash Global DNA Methylation (5-mc) ELISA In the present study, we analyzed the associations and corre- Easy Kit (Colorimetric)] and global DNA hydroxymethylation lations among global DNA methylation (5-mc) and DNA hydrox- [MethylFlash Global DNA Hydroxymethylation (5-hmc) ELISA Easy ymethylation (5-hmc) markers, expression levels of associated Kit (Colorimetric)] assays were carried out according to the man- genes (DNMTs, TETs, and MBDs), oxidative stress biomarkers (8- ufacturer’s instructions using an ELISA kit (Epigentek Group Inc., OHdG and MDA), and DNA repair genes (OGG1, MHT1, ERCC1, NY, USA). Briefly, 1e8 mL (100 ng) of DNA was added to the wells. XPA, and XPC) in subsamples of longitudinal studies (sampling and The samples were incubated at 37 C for 90 min, followed by the assessment for two time points) of the HSOS in Taean, Korea. addition of capture and detection antibodies. The absorbance was read at 450 nm. A standard curve was generated from the plot of OD 2. Materials and methods values relative to those of the positive controls. 2.1. Study population and sample (urine and blood) collection 2.4. Measurement of MDA and 8-OHdG levels The number of adults (aged 18 years or older) who agreed to We used the existing results of MDA and 8-OHdG levels participate in the survey of the cohort study were 9585 from 2009 measured in the previous study of the cohort (Noh et al., 2015). to 2017. From the high exposed area (AH), the number of partici- Briefly, urinary MDA levels were determined by measuring the pants in 2009 (the baseline survey) was 1741 whereas in 2014 (the levels of thiobarbituric acid reactive substances using a high- follow-up survey) only 615 adults were participated (Fig. 1). The performance liquid chromatography instrument equipped with a references of this cohort study was from the low exposed area of fluorescence detector (Agarwal and Chase, 2002). Urinary 8-OHdG same county with that of high exposed area but distant from the levels were determined using an 8-OHdG competitive enzyme- oil-spill accident site. The adult participants (AL) from low-exposed linked immunosorbent assay (ELISA) kit (Japan Institute for the group were 7505 at baseline survey in 2009 while only 187 adults Control of Aging, Kyoto, Japan) (Noh et al., 2015). were participated in follow-up survey in 2014 (Fig. 1).
Load more

Recommended publications
  • Outbreak of an Exotic Flatid, Metcalfa Pruinosa (Say) (Hemiptera
    Journal of Asia-Pacific Entomology 14 (2011) 473–478 Contents lists available at ScienceDirect Journal of Asia-Pacific Entomology journal homepage: www.elsevier.com/locate/jape Short Communication Outbreak of an exotic flatid, Metcalfa pruinosa (Say) (Hemiptera: Flatidae), in the capital region of Korea Yeyeun Kim a, Minyoung Kim a, Ki-Jeong Hong b, Seunghwan Lee a,⁎ a Entomology Program, Department of Agricultural Biotechnology, Research Institute for Agriculture and Life Science, Seoul National University, 599 Gwanak-ro, Gwanak-gu, Seoul, 151-921, Republic of Korea b Pest Risk Assessment Division, National Plant Quarantine Service, 178 Anyang-ro, Manan-gu, Anyang-si, Gyeonggi-do, 430-015, Republic of Korea article info abstract Article history: The citrus flatid planthopper, Metcalfa pruinosa (Say, 1830) (Hemiptera: Flatidae), has a native distribution in Received 2 December 2010 eastern North America, It has recently invaded Italy in 1979 and has since spread to other European countries. Revised 1 June 2011 In 2009, Metcalfa pruinosa was discovered in Seoul and the Gyeonggi Province, Republic of Korea. This is the Accepted 4 June 2011 first record in the eastern part of Palaearctic. One year after its discovery, in July 2010, we found significant Available online 29 June 2011 populations and serious damage on many deciduous forest trees, ornamental trees, and agricultural crops in central regions of the Korean Peninsula. In this paper, we report the status of the outbreak and discuss the Keywords: Hemiptera biology, morphological characters, distribution, host plants, and the importance of M. pruinosa as a potential Flatidae insect pest in the Korean Peninsula. Metcalfa pruinosa © Korean Society of Applied Entomology, Taiwan Entomological Society and Malaysian Plant Protection Invasion Society, 2011.
    [Show full text]
  • ICLEI East Asia Secretariat Annual Report 2014
    ICLEI East Asia Secretariat Annual Report 2014 www.eastasia.iclei.org CONTENT GREETINGS P.1-2 PROFILE p.3 GOVERNANCE p.4 STRATEGIC DEVELOPMENT p.5-6 PROGRAMS & PROJECTS p.7-8 CAPACITY BUILDING p.9-10 OUR STAFF p.11-13 GREETINGS From the Founding Director East Asia continues to be the world’s most thriving region. ICLEI is proud to have enlarged its presence and capacity to support East Asian cities in their sustainability efforts and to engage them in our programs. The ICLEI East Asia Secretariat has launched two programs this past year. The Energy-safe Cities East Asia program works with three cities each from China, Japan and South Korea and one Mongolian city to explore with which currently available technologies and at what costs the cities could transform their urban energy systems to become low-carbon, low-risk and resilient – practically 100% renewable – by the year 2030. True, it is an ambitious approach, but how can we make a difference if we are not ambitious? After one and a half year of preparations we have launched the program with a first experts symposium held in Beijing in October 2014. As a precursor of a Green Public Procurement program for Chinese cities we have organized EcoProcura© China 2014, an international symposium in Beijing that brought experts from the Chinese government, international organizations, Chinese as well as foreign cities together for an exchange of information, practices and experiences. We have been present at key events in China and spurred attention to resilience in urban planning and management and brisked up the discussion on car-centered urban development by calling for EcoMobility-oriented planning.
    [Show full text]
  • Community Adaptation to the Hebei-Spirit Oil Spill
    Copyright © 2012 by the author(s). Published here under license by the Resilience Alliance. Cheong, S. 2012. Community adaptation to the Hebei-Spirit oil spill. Ecology and Society 17(3): 26. http://dx.doi.org/10.5751/ES-05079-170326 Insight, part of a Special Feature on Vulnerability and Adaptation to Oil Spills Community Adaptation to the Hebei-Spirit Oil Spill So-Min Cheong 1 ABSTRACT. The focus of the research is the significance of dependence for communities to survive and adapt in times of environmental disasters. It shifts the emphasis on self-reliant communities for survival and examines the types and effects of dependence and external linkages by analyzing the range of community responses that include initial responses, early social impact, compensation, and conflicts after the Hebei-Spirit oil spill in December 2007 in Korea. The findings reveal that dependence is necessary, and the effects of dependence can be both positive and negative depending on the relations between external entities and affected communities as well as the community capacity to absorb resources and information. Key Words: community adaptation; community dependence; resource; Hebei-Spirit; knowledge; oil spill INTRODUCTION and negative depending on the relations between external How do communities adapt to new environmental disasters? entities and affected communities. A paradigm within the literature on disaster management and climate change adaptation is the promotion of self-reliance BACKGROUND and self-sufficiency, for communities to initiate action to Though the advocacy of community-initiated disaster prevent and prepare for disasters and to determine for preparedness and adaptation is important to increasing themselves how to manage and adapt to disasters and climate adaptive capacity and sharing local knowledge, local-centered change (Allen 2006).
    [Show full text]
  • Disaster Management in Korea by So Eun Park May 5 2015
    DISASTER MANAGEMENT IN KOREA SO EUN PARK Student Intern at IIGR (International Institute of Global Resilience) Graduated from Ewha Womans University May 5, 2015 Table of Contents I. Executive Summary………………………………………………………………………………………………………………p1 II. Introduction....……...…….……………………………….…………………………………………………………………….p2 A. Background 1) Geographical Background 2) Social, Cultural Issues B. History of Korea Disaster Management C. Policies and Organizations III. Current Status…………………………………………………………………………………………………….……………p15 A. NEMA 1) Overview 2) What NEMA Accomplished 3) Major Disasters (2004 ~ 2014) 4) Problems B. MPSS 1) Overview 2) MPSS Goal 3) Major Incidents Since the Establishment of MPSS C. Disaster Volunteerism in Korea IV. Observations, Recommendations, and Conclusion ………....................................................p40 Disaster Management in Korea by So Eun Park | May 5, 2015 Ⅰ. Executive Summary To many Koreans, the concept of disaster management will be relatively new and unfamiliar since people often thought of disasters as destiny, and as the government historically did not put much effort into “managing” disasters with an effective system. It is only after Sewol ferry incident of 2014 that Koreans began to realize how important it is to effectively manage disasters, which can happen anytime, anywhere, without warning. In recent years, the Korean government has taken steps to improve the country’s disaster management system, first by establishing the National Emergency Management Agency (NEMA) in 2004, and then by replacing NEMA with the newly-created Ministry of Public Safety and Security (MPSS) in 2014. However, to the author, it is unclear as to whether the government is ready to admit the mistakes of the past, learn from the past tragedies, and really try to change the country’s approach to emergency management.
    [Show full text]
  • Burden of Disease Attributable to the Hebei Spirit Oil Spill in Taean, Korea
    Downloaded from http://bmjopen.bmj.com/ on November 13, 2015 - Published by group.bmj.com Open Access Research Burden of disease attributable to the Hebei Spirit oil spill in Taean, Korea Young-Min Kim,1 Jae-Hyun Park,2 Kyusik Choi,2 Su Ryeon Noh,3 Young-Hyun Choi,3 Hae-Kwan Cheong2 To cite: Kim Y-M, Park J-H, ABSTRACT et al ARTICLE SUMMARY Choi K, . Burden of Objectives: We aimed to assess the burden of disease attributable to the disease (BOD) of the residents living in contaminated Hebei Spirit oil spill in Taean, Strength and limitations of this study coastal area with oil spill and also analysed the BOD Korea. BMJ Open 2013;3: ▪ This is the first study to quantify the burden of e003334. doi:10.1136/ attributable to the oil spill by disease, age, sex and disease (BOD) of a single environmental bmjopen-2013-003334 subregion. disaster. Design: Health impact assessment by measuring ▪ This study demonstrates that BOD is an objective years lived with disability (YLD) due to an oil spill. ▸ Prepublication history and and comprehensive metric for estimating and additional material for this Setting: A whole population of a community affected comparing the health effects of environmental paper is available online. To by an anthropogenic environmental disaster and hazards and disasters across different regions view these files please visit secondary health outcome data. and time periods. the journal online Participants: Based on the health outcome survey ▪ To estimate excess incidence, we used preva- (http://dx.doi.org/10.1136/ including 10 171 individuals (male 4354; female lence data classified by distance from the con- bmjopen-2013-003334).
    [Show full text]
  • Socio-Ecological Resilience of Oil Spill: Focusing on the Hebei Spirit Oil Spill on the West Coast of Korea
    I J A B E R, Vol. 14, No. 15 (2016): 10793-10808 SOCIO-ECOLOGICAL RESILIENCE OF OIL SPILL: FOCUSING ON THE HEBEI SPIRIT OIL SPILL ON THE WEST COAST OF KOREA Gi-Geun Yang* and Kwang Bin Bae** Abstract: Purpose of this paper: The purpose of this study is to examine the relationship between the socio-ecological impacts and resilience of the Hebei Spirit Oil Spill (HSOS). This study analyzes the ecological and social impacts and social and ecological resilience of HSOS from the perspective of the Ecological Impacts (oil spill itself, physical environment of the marine, and marine biology), Social Impacts (disaster management, economy, compensation), and Social and Ecological Resilience (human health and community resilience, policy and decision). Design/methodology/approach: In order to examine the socio-ecological impacts, this study conducts a comprehensive literature review, which includes government and industry papers and reports related to oil spills and their environmental and societal consequences. The literature consists largely of case studies, the Ministry of Land, Transport and Maritime Affairs’ Hebei Spirit oil spill white papers, reports on inspection ruling from Seosan local court concerning HSOS compensation by area and type of business, and secondary statistics from published academic journals. In addition, we also conducted an interview in 2008 near the damaged area regarding conflicts between resident groups and communities. Findings: This study presents several suggestions on methods to restore damage caused by an oil spill. First, it is necessary to establish long- and mid-term strategies to restore the ecosystem. Second, not only do governments and local societies need to put effort into revitalizing the affected local economy but also focus more on social and ecological resilience.
    [Show full text]
  • Cittaslow List
    Cittaslow International Network: 252 Città presenti in 30 Paesi ed aree territoriali nel Mondo Cittaslow International Network: 252 Cities present in 30 Countries and territorial areas in the World *Lista aggiornata nel settembre 2018/List updated in September 2018 CITTASLOW LIST • Cittaslow Australia Goolwa Katoomba Yea • Cittaslow Austria Enns Hartberg Horn • Cittaslow Belgium Chaudfontaine Enghien Estinnes Lens Maaseik Silly • Cittaslow Canada Cowichan Bay Lac-Mégantic Naramata Wolfville • Cittaslow China Changshan - Zigang _In progress Fuli (Fuchuan Yao Autonomous County) Jingyang ( Jingde County) Luzhi (Wuzhong District) Shimenshan (Qufu city) Songbai (Shennongjia Forest District) Yanyang (Meizhou city) Yaxi (Gaochun County) Yuhu (Wencheng County) • Cittaslow Colombia Pijao • Cittaslow Denmark Mariagerfjord Svendborg • Cittaslow Finland Kristinestad • Cittaslow France Créon Labastide d’Armagnac Loix Mirande Saint Antonin Noble Val Samatan Segonzac Simorre Valmondois • Cittaslow Germany Bad Essen Bad Schussenried Berching Bischofsheim Blieskastel Deidesheim Hersbruck Lüdinghausen Maikammer Meldorf Michelstadt Nördlingen Penzlin Schneverdingen Spalt Überlingen Waldkirch Wirsberg Zwingenberg • Cittaslow Great Britain Aylsham Berwick upon Tweed Llangollen Mold Perth • Cittaslow Hungary Hódmezővásárhely • Cittaslow Iceland Djupavogshreppur • Cittaslow Ireland Clonakilty • Cittaslow Italy Abbiategrasso Acqualagna Acquapendente Altomonte Amalfi Amelia Anghiari Asolo Barga Borgo Val di Taro Bra Brisighella Bucine Caiazzo Capalbio Casalbeltrame
    [Show full text]
  • Incidents Involving the Iopc Funds – 1992 Fund
    Agenda item: 3 IOPC/JUN10/3/5/1 Original: ENGLISH 7 June 2010 INTERNATIONAL OIL POLLUTION COMPENSATION FUNDS 1992 Fund Executive Committee 92EC48 ● 1992 Fund Working Group 92WG6/1 INCIDENTS INVOLVING THE IOPC FUNDS – 1992 FUND HEBEI SPIRIT Submitted by the Republic of Korea Summary: This document contains information on the pollution caused by the Hebei Spirit incident off the west coast of the Republic of Korea and the measures taken by the affected State following the incident. Action to be taken: 1992 Fund Executive Committee: The Executive Committee is invited to take note of the information provided to facilitate prompt and adequate compensation to the affected residents, and also to review and discuss the proposal requesting the Fund to make payments of 100% of the assessed amount, which is the agreement being followed by the relevant P&I Club. 1 Introduction 1.1 This document is submitted in order to enhance the overall understanding of Member States regarding the massive oil spill incident which took place off the coast of Taean County, South Chungcheong Province, Republic of Korea on 7 December 2007 following the collision between a barge and the M/T Hebei Spirit, resulting in a spill of 12 547kl of crude oil. 1.2 This document invites the Executive Committee to review and render a decision on the proposal of the Republic of Korea, which requests that the Fund, along with the P&I Club, make full payments of the assessed amount up to the maximum compensation limit set forth by the 1992 Fund Convention, and safety mechanisms that the Korean Government should ensure and guarantee to that end.
    [Show full text]
  • A Study of Perceptions of How to Organize Local Government Multi-Lateral Cross- Boundary Collaboration
    Title Page A Study of Perceptions of How to Organize Local Government Multi-Lateral Cross- Boundary Collaboration by Min Han Kim B.A. in Economics, Korea University, 2010 Master of Public Administration, Seoul National University, 2014 Submitted to the Graduate Faculty of the Graduate School of Public and International Affairs in partial fulfillment of the requirements for the degree of Doctor of Philosophy University of Pittsburgh 2021 Committee Membership Page UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC AND INTERNATIONAL AFFAIRS This dissertation was presented by Min Han Kim It was defended on February 2, 2021 and approved by George W. Dougherty, Jr., Assistant Professor, Graduate School of Public and International Affairs William N. Dunn, Professor, Graduate School of Public and International Affairs Tobin Im, Professor, Graduate School of Public Administration, Seoul National University Dissertation Advisor: B. Guy Peters, Maurice Falk Professor of American Government, Department of Political Science ii Copyright © by Min Han Kim 2021 iii Abstract A Study of Perceptions of How to Organize Local Government Multi-Lateral Cross- Boundary Collaboration Min Han Kim University of Pittsburgh, 2021 This dissertation research is a study of subjectivity. That is, the purpose of this dissertation research is to better understand how South Korean local government officials perceive the current practice, future prospects, and potential avenues for development of multi-lateral cross-boundary collaboration among the governments that they work for. To this purpose, I first conduct literature review on cross-boundary intergovernmental organizations, both in the United States and in other countries. Then, I conduct literature review on regional intergovernmental organizations (RIGOs).
    [Show full text]
  • Conservation and Rehabilitation of Habitats for Key Migratory Birds in North-East Asia with Special Emphasis on Cranes and Black-Faced Spoonbills
    (DRAFT) PROJECT REPORT Conservation and Rehabilitation of Habitats for Key Migratory Birds in North-East Asia with special emphasis on Cranes and Black-faced Spoonbills Edited by Korean Society of Environment and Ecology (KSEE) Edited by Sunyoung Park (Ms.) [email protected] Conservation Programme Advisor, WWF-Korea Korean Society of Environment and Ecology (KSEE) The Korean Society of Environment and Ecology (KSEE) was founded in 1987 and is designed to make a significant contribution to a sustainable development of human being and an improved global environment by conducting research, providing and applying the research results in the areas of Ecosystem Management & Conservation, Environmental Education and Ecosystem Restoration. Address: (06130) #910, 22, Teheran-ro 7-gil, Gangnam-gu, Seoul, 06130, Korea Tel: +82-70-4194-7488 Fax: 82-70-4145-7488 E-mail: [email protected] Homepage: http://www.enveco.org Disclaimer The views expressed in this report are those of editor and/or KSEE and do not necessarily reflect any opinion or policy of NEASPEC and/or UNESCAP-ENEA office. Cover image Copyright © KIM Yeonsoo Recommended Citation KSEE (ed.) 2016. Conservation and Rehabilitation of Key Habitats for Key Migratory Birds in North-East Asia with special emphasis on Cranes and Black-faced Spoonbills (2013-2016). Incheon: UNESCAP-ENEA and NEASPEC Acronyms and abbreviations BFS Black-faced Spoonbill CCZ Civilian Control Zone (ROK) DIPA Dauria International Protected Area DMZ De-militarized Zone DTMN Dauria Transboundary Monitoring Network
    [Show full text]
  • For Peer Review Only
    BMJ Open BMJ Open: first published as 10.1136/bmjopen-2013-003334 on 20 September 2013. Downloaded from Burden of disease attributable to the Hebei Spirit oil spill in Taean, Korea ForJournal: peerBMJ Open review only Manuscript ID: bmjopen-2013-003334 Article Type: Research Date Submitted by the Author: 06-Jun-2013 Complete List of Authors: Kim, Young-Min; Rollins School of Public Health, Emory University, Department of Environmental Health Park, Jae-Hyun; Sungkyunkwan University School of Medicine, Department of Social and Preventive Medicine Choi, Kyusik; Sungkyunkwan University School of Medicine, Department of Social and Preventive Medicine Noh, Su Ryeon; Taean Environmental Health Center, Choi, Young-Hyun; Taean Environmental Health Center, Cheong, Hae-Kwan; Sungkyunkwan University School of Medicine, Department of Social and Preventive Medicine <b>Primary Subject Public health Heading</b>: Secondary Subject Heading: Epidemiology, Health economics, Occupational and environmental medicine EPIDEMIOLOGY, HEALTH ECONOMICS, Epidemiology < THORACIC http://bmjopen.bmj.com/ Keywords: MEDICINE, MENTAL HEALTH, TOXICOLOGY on October 1, 2021 by guest. Protected copyright. For peer review only - http://bmjopen.bmj.com/site/about/guidelines.xhtml Page 1 of 25 BMJ Open BMJ Open: first published as 10.1136/bmjopen-2013-003334 on 20 September 2013. Downloaded from 1 2 3 4 Burden of disease attributable to the Hebei Spirit oil spill in 5 6 7 Taean, Korea 8 9 10 Young-Min Kim1 , Jae-Hyun Park2, Kyusik Choi2, Su Ryeon Noh3, Young-Hyun Choi3, Hae- 11
    [Show full text]
  • Korean TV Dramas and the Selling of Place by Youjeong
    Spectacular Cities, Speculative Storytelling: Korean TV Dramas and the Selling of Place By Youjeong Oh A dissertation submitted in partial satisfaction of the requirements for the degree of Doctor of Philosophy in Geography in the Graduate Division of the University of California, Berkeley Committee in charge: Professor You-tien Hsing, Chair Professor Richard A. Walker Professor Barrie Thorne Professor Paul E. Groth Fall 2013 Abstract Spectacular Cities, Speculative Storytelling: Korean TV Dramas and the Selling of Place By Youjeong Oh Doctor of Philosophy in Geography University of California, Berkeley Professor You-tien Hsing, Chair This dissertation examines the relationships between popular culture, cities, and gendered social discourses, with a focus on contemporary Korean television dramas. Existing studies about Korean dramas have relied upon economic and cultural analysis to, in effect, celebrate their vibrant export to overseas markets and identify why they are popular in other East Asian countries. This study expands the scope into spatial and social realms by examining cities’ drama-sponsorship and drama-driven social activities. Deploying popular culture as an analytical category directly shaping and transforming material, urban and social conditions, I argue that the cultural industry of Korean television dramas not only functions as its own, dynamic economic sector, but also constitutes urban processes and social discourses of contemporary South Korea. Drawing upon interdisciplinary methods including ethnography and content analysis, I examine Korean television dramas from the multiple vantage points of producers, audience, storytelling, and city-sponsorship, and elucidate why and how these four arenas are deeply intertwined. Their mutual entanglement, in turn, requires us to see Korean television dramas as more than just commercial entertainment; they become a medium through which we can contemplate labor conditions in the cultural industry, the political economies of development in regional cities, and gender politics in Korea.
    [Show full text]