linica f C l To o x l ic a o n r l o u g o y J Acevedo, et al., J Clin Toxicol 2015, 5:1 Journal of Clinical Toxicology DOI: 10.4172/2161-0495.1000232 ISSN: 2161-0495 Research Article Open Access Cytotoxic and Anti-inflammatory Activities of Bursera species from Mexico Macdiel Acevedo1, Pablo Nuñez1, Leticia Gónzalez-Maya2, Alexandre CardosoTaketa1 and María Luisa Villarreal1* 1Centro de Investigación en Biotecnología, Universidad Autónoma del Estado de Morelos, Av. Universidad 1001, Col. Chamilpa, Cuernavaca Morelos , México 2Facultad de Farmacia, Universidad Autónoma del Estado de Morelos, Av. Universidad 1001, Col. Chamilpa, Cuernavaca, México *Corresponding author: María Luisa Villarreal, Centro de Investigación en Biotecnología, Universidad Autónoma del Estado de Morelos, Av. Universidad 1001, Col. Chamilpa, Cuernavaca Morelos, México, Tel: +51 777 3297057; Fax: 51 777 3297030; E-mail:
[email protected] Received date: Nov 13, 2014; Accepted date: Feb 19, 2015; Published date: Feb 21, 2015 Copyright: © 2015, Acevedo M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Abstract Objective: Organic extracts from nine species (eleven populations) of the Bursera genus native to Mexico, were investigated for cytotoxic and anti-inflammatory activities. The influence of the cytotoxic plant extracts on cell cycle progression and apoptosis were also analyzed. Materials and methods: Cytotoxic activity from B. ariensis (Kunth) McVaugh and Rzed. Kew Bull (two populations), B. bicolor Engl., B. lancifolia Engl., B. glabrifolia Engl.