DOCSLIB.ORG

The Florey Annual Report 2013 Read →

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text

Load more

THE FLOREY ANNUAL REPORT 2013 OUR MISSION To improve lives through brain research OUR VISION To create significant knowledge about the brain OUR VALUES Generate scientific knowledge to improve global health Innovate and problem-solve Work together with integrity Share our discoveries with our supporters and partners OUR COVER Associate Professor Julie Bernhardt’s career continues to be recognised with a range of awards, fellowships and publications in the field of stroke rehabilitation. In 2013, Julie, left, not only pursued her research, but mentored several young scientists – men and women. Dr Emma Burrows, centre, from the cognitive neuroscience division, is one such beneficiary of Julie’s experience. Julie’s support is mirrored by philanthropists like Ms Naomi Milgrom, right, who has made a significant contribution to the Florey’s Women in Science program. Naomi has a long relationship with the Florey, dating back to nearly a decade on the Board and more recently, taking an active interest in the Florey’s progress towards a more supportive workplace for women. THE FLOREY INSTITUTE OF NEUROSCIENCE & MENTAL HEALTH ANNUAL REPORT 2013 3 TABLE OF CONTENTS Our mission, vision and values 1 Untangling the wires in our heads 68 About us 4 Huntington’s – searching for a cure 70 Why do we study the brain? 6 Schizophrenia – the push to find some answers 72 Florey in a flash 7 The Florey’s impact on schizophrenia 73 Chairman’s & Director’s report 8 The financial cost of mental illness 73 Chief Operating Officer’s report 11 Unravelling the secrets of Alzheimer’s disease 86 Repairing a vulnerable brain 12 When changing a nappy is exciting 112 Taking care of business 14 Save a minute, save a day 125 Neuroscience Trials Australia 16 When stroke becomes dementia 126 Neuroscience for the next generation 18 Our brain’s fundamental need for salt 127 Foundation Council Chairman’s report 19 Florey students team-up for excellence 132 Board of Directors 22 Florey Governors 135 Division heads 28 Board committees & Foundation Council 136 Equality in Science report 32 The Florey Faculty & senior positions 137 The science 34 It is Pozible 139 Jess and her iPad loving mice 39 Our donors 140 The global health challenge of neurological disorders 40 Financial statements 144 Meet the team from the Developmental Psychobiology lab 49 Our people 146 4 THE FLOREY INSTITUTE OF NEUROSCIENCE & MENTAL HEALTH ANNUAL REPORT 2013 THE FLOREY INSTITUTE OF NEUROSCIENCE & MENTAL HEALTH ANNUAL REPORT 2013 5 ABOUT US ADDICTION ALZHEIMER’S DISEASE CARDIOVASCULAR DISEASE MENTAL ILLNESS EPILEPSY HUNTINGTON’S DISEASE he Florey Institute of Neuroscience and Mental Health is one of the largest brain research centres in the world and MOTOR NEURONE DISEASE the biggest in Australia. Our scientists share a common T MULTIPLE SCLEROSIS goal – to improve people’s lives through brain research and, ultimately, to influence global wellbeing and health economics. PARKINSON’S DISEASE We employ 596 staff and educate approximately 120 post- graduate students each year. STROKE Neuroscience is an area of medical research attracting enormous SUDDEN INFANT DEATH SYNDROME attention as our understanding of the brain rapidly evolves. Internationally, populations are ageing and there is a sense of TRAUMATIC BRAIN AND urgency to find causes, treatments and cures for conditions SPINAL CORD INJURY affecting the brain and mind. We need to address these conditions to avoid suffering and to contain health-related expenditure. The Florey is a world-leader in imaging technology, genetics, stroke rehabilitation and epidemiological studies. Mental health research is also a growing focus with psychotic illnesses and neurodegenerative diseases demanding attention. 6 THE FLOREY INSTITUTE OF NEUROSCIENCE & MENTAL HEALTH ANNUAL REPORT 2013 THE FLOREY INSTITUTE OF NEUROSCIENCE & MENTAL HEALTH ANNUAL REPORT 2013 7 FLOREY IN A FLASH WHY DO WE STUDY THE BRAIN? STAFF AND STUDENTS TOTAL STUDENTS HONORARIES FLOREY FACULTY he human brain — a spongy, 1.5kg mass of tissue — is the most complex living structure. It has the capacity T to store more information than a supercomputer and to create a network of connections far superior to any social network. The brain has enabled humans to achieve SCIENTIFIC AND TECHNICAL breathtaking milestones — exploring the solar system, PHD STUDENTS SUPPORT STAFF ALUMNI mapping the human genome and composing masterpieces of art, literature, and music. Scientists still have not uncovered the full extent of what the brain can do. This single organ controls every aspect of our lives, ranging from heart rate and appetite to emotion and memory. The brain controls the immune system’s response to disease and determines, in part, how well people respond to medical treatments. It shapes our thoughts, beliefs, dreams and imagination. Neuroscientists specialise in the study of the brain and the nervous system. We are inspired to decipher the brain’s command over all its diverse functions. In the last 30 years, the 24 538 2823 neuroscience field has made enormous progress. We continue to strive for a deeper understanding of how the brain’s 100 billion Countries represented by our Papers, chapters, books edited Scientific publications nerve cells are born, grow, and connect. We study how these staff and students and abstracts in 2013 published over 10 years cells organise themselves into effective, functional circuits that usually remain in working order for life. Brain researchers are motivated to understand behaviour. How do cell circuits enable us to read and speak? How and why do we form relationships? How do we think, remember, despair, or motivate? We are discovering possible causes of devastating disorders of the brain and body, as well as ways to prevent or cure SCIENTIFIC PAPERS CUMULATIVE CITATIONS AVERAGE CITATION them. We strive to understand how the world around us works. Scientific papers published Cumulative citations of scientific Average citation over 10 years in 2013 publications over 10 years 100 AVERAGE CITATIONS 564 H-index Average citations per item 2013 Citations cumulative 2013 Adapted from a piece written by the Society for Neuroscience. 8 THE FLOREY INSTITUTE OF NEUROSCIENCE & MENTAL HEALTH ANNUAL REPORT 2013 THE FLOREY INSTITUTE OF NEUROSCIENCE & MENTAL HEALTH ANNUAL REPORT 2013 9 Chairman’s & Director’s Report Chairman’S & DIRECTor’S REPORT s the Florey Institute of Neuroscience and Mental Health celebrates its 50th Report from the Chairman of the anniversary, we have been reflecting on our achievements and also looking Board, Mr Harold Mitchell AC, and the A forward to a new era in medical research. The Florey has evolved to become Scientific Director, Professor Geoffrey Donnan part of a sector that is a world-class asset to Australia’s economy, delivering significant dividends through highly successful academic activity and biotech ingenuity. The Florey’s work directly benefits the health of Australians. In fact, research conducted during 2013 has had an international impact, by influencing the way people are treated within hours of a stroke as well as encouraging changes in rehabilitation practice to ensure the damaged brain’s plasticity is given the very best chance to make new connections. These are just two of the significant pieces of work you will read about in this report. Within the next five years, investment in translational research into chronic neurological diseases and mental health will be critical to prevent an unprecedented health care crisis. By 2020, 5.5 million baby boomers (20% of current workers) will be leaving the workforce. Longer life expectancy means there will be an increase in the incidence of chronic diseases of brain and mind (stroke, dementia and mental illness) and associated disability in this population. Health care costs are projected to double by 2050. What we need to avert this crisis is a coordinated frontier program of research focused on translation that changes clinical practice in the treatment of chronic neurological diseases and mental illness. Florey researchers are focussed on the role they will play in helping to maintain healthy brains from adolescence through full maturity and ageing. Our work will contribute to the nation’s need for a productive, engaged population with high levels of workforce participation throughout life. With imaging and genetics now providing fundamental insights to modern medicine, the Florey is beautifully positioned to confront these future health challenges, led by extraordinary scientific leaders. Today the Florey accommodates 600 people, including more than 120 students, and we work with neuroscientists from 34 countries. We plan to grow even more in the next few years and to collaborate with an even wider range of partners. During 2013, the Florey joined with the Australian Football League to use our sophisticated imaging equipment to assess the long-term impact of concussion on football players. Professor Graeme Jackson, neurologist and senior deputy director of the Florey, is keen to create a Centre of Research Excellence, bringing key researchers together so that athletes – from little six-year old contenders through to professional players – are offered the best advice to stay safe when competing. Professor Jackson and his team also refined imaging techniques that not only identify types of epilepsy but help neurosurgeons operate with greater accuracy. Professor Ingrid Scheffer continued in her extraordinary quest to identify the genes responsible for a range of serious childhood epilepsies, winning a major award on the way. Our Alzheimer’s researchers have contributed to a major advance: we are close to being able to provide a blood test that will identify biological markers associated with the toxic protein called amyloid beta. It could help identify those at risk of dementia 10 THE FLOREY INSTITUTE OF NEUROSCIENCE & MENTAL HEALTH ANNUAL REPORT 2013 THE FLOREY INSTITUTE OF NEUROSCIENCE & MENTAL HEALTH ANNUAL REPORT 2013 11 CHIEF OPERATING OFFICer’S REPORT Chairman’s & Director’s Report Report from the Chief Operating Officer, Gary Gray up to 17 years before symptoms appear, along with scanning and cognitive testing.
Recommended publications
  • 書 名 等 発行年 出版社 受賞年 備考 N1 Ueber Das Zustandekommen Der

    書 名 等 発行年 出版社 受賞年 備考 N1 Ueber Das Zustandekommen Der

    書 名 等 発行年 出版社 受賞年 備考 Ueber das Zustandekommen der Diphtherie-immunitat und der Tetanus-Immunitat bei thieren / Emil Adolf N1 1890 Georg thieme 1901 von Behring N2 Diphtherie und tetanus immunitaet / Emil Adolf von Behring und Kitasato 19-- [Akitomo Matsuki] 1901 Malarial fever its cause, prevention and treatment containing full details for the use of travellers, University press of N3 1902 1902 sportsmen, soldiers, and residents in malarious places / by Ronald Ross liverpool Ueber die Anwendung von concentrirten chemischen Lichtstrahlen in der Medicin / von Prof. Dr. Niels N4 1899 F.C.W.Vogel 1903 Ryberg Finsen Mit 4 Abbildungen und 2 Tafeln Twenty-five years of objective study of the higher nervous activity (behaviour) of animals / Ivan N5 Petrovitch Pavlov ; translated and edited by W. Horsley Gantt ; with the collaboration of G. Volborth ; and c1928 International Publishing 1904 an introduction by Walter B. Cannon Conditioned reflexes : an investigation of the physiological activity of the cerebral cortex / by Ivan Oxford University N6 1927 1904 Petrovitch Pavlov ; translated and edited by G.V. Anrep Press N7 Die Ätiologie und die Bekämpfung der Tuberkulose / Robert Koch ; eingeleitet von M. Kirchner 1912 J.A.Barth 1905 N8 Neue Darstellung vom histologischen Bau des Centralnervensystems / von Santiago Ramón y Cajal 1893 Veit 1906 Traité des fiévres palustres : avec la description des microbes du paludisme / par Charles Louis Alphonse N9 1884 Octave Doin 1907 Laveran N10 Embryologie des Scorpions / von Ilya Ilyich Mechnikov 1870 Wilhelm Engelmann 1908 Immunität bei Infektionskrankheiten / Ilya Ilyich Mechnikov ; einzig autorisierte übersetzung von Julius N11 1902 Gustav Fischer 1908 Meyer Die experimentelle Chemotherapie der Spirillosen : Syphilis, Rückfallfieber, Hühnerspirillose, Frambösie / N12 1910 J.Springer 1908 von Paul Ehrlich und S.
  • Fleming Vs. Florey: It All Comes Down to the Mold Kristin Hess La Salle University

    Fleming Vs. Florey: It All Comes Down to the Mold Kristin Hess La Salle University

    The Histories Volume 2 | Issue 1 Article 3 Fleming vs. Florey: It All Comes Down to the Mold Kristin Hess La Salle University Follow this and additional works at: https://digitalcommons.lasalle.edu/the_histories Part of the History Commons Recommended Citation Hess, Kristin () "Fleming vs. Florey: It All Comes Down to the Mold," The Histories: Vol. 2 : Iss. 1 , Article 3. Available at: https://digitalcommons.lasalle.edu/the_histories/vol2/iss1/3 This Paper is brought to you for free and open access by the Scholarship at La Salle University Digital Commons. It has been accepted for inclusion in The iH stories by an authorized editor of La Salle University Digital Commons. For more information, please contact [email protected]. The Histories, Vol 2, No. 1 Page 3 Fleming vs. Florey: It All Comes Down to the Mold Kristen Hess Without penicillin, the world as it is known today would not exist. Simple infections, earaches, menial operations, and diseases, like syphilis and pneumonia, would possibly all end fatally, shortening the life expectancy of the population, affecting everything from family-size and marriage to retirement plans and insurance policies. So how did this “wonder drug” come into existence and who is behind the development of penicillin? The majority of the population has heard the “Eureka!” story of Alexander Fleming and his famous petri dish with the unusual mold growth, Penicillium notatum. Very few realize that there are not only different variations of the Fleming discovery but that there are also other people who were vitally important to the development of penicillin as an effective drug.
  • Howard-Florey-Maker

    Howard-Florey-Maker

    _ ....II""lle,st'Ol)' of "Ie lin ~t tlt:Mc 'c y~ successfullY to rmat. pea WIth ~ IJ&. iBfoctiOus'diseases - begins-with &bit Qf IuC AI~ PI tIlil1g, a .S 9itisb ~lientlst.notlcEid In t$!B ftJal mould.,ad l:!"eveAted growth of ~ qerms {bacterial 1., lils ~ the ~In plot 0 me story 1'I0J0IYl1l$ Sr ~pvay Qf penidll 10 ~ years la1er by arl·Aus\ 1;1 Sdetl bam t'!undred s R Y~'89D this year, H'owar~ I: fIotey and h d ~ team's ~ systttma!JQ, detalla wotk "'~ Jl 11_ fJTIed petlicilin from an 53 i[l~1Jlg o~ , nto-a life saver. ' Emma ,au fY 50 IJSOO to tm e teliladll', at t'l'wiMlstral r:Ja • U verslty's JOOf\ CtJrti[l Scbool of Moolaal Rasecll'eh (HQw FJor~ ptayed 8 c roI'a II'l the-est)bllshmflnt at itI& School god ~!lr'S1ty t In h 11M), TIll> !/O"'"_....... ot l!1te.dJ1l1II d1Haie'&."4ICh .. po.~a~1I ~ Erl'1lil"1a's.lile w~!i8Vedby penicillin irllll IIlIaod .. 1111 IIihi' 1111\1:_ tva ~ntil>iol~; 8uI1hft;e phDl Cl(a pauilftl n Get'rJ1art refiJg g mp. tt WQf1d War II. ,1<42 -"ow ho"; b.d thlnP COIH~. Pft_ 1 lind Imagine hO\ she fett any years later. 2 ~ '1M .III~ !It II YOUl1'llll1J1 willi _I J."..,tllltw...... OlIl1dltlicln ,..,_by the tt.iituI t cooid~ blITlping iHlo mtJY wh fa lIay ..fI...boiIJg IIlven penldll" {JItIiJID 3" _ hIld ~ woriled- the man who made tile shown .~"in.IH",p"'-.ntIIIf tbll JIIII!Ilt dllly g~pIy mpooicillin ~bte.
  • Monash News, December 2003 Appointment Boosts Meteorology Leadership Briefly Mathematical Sciences Intemationally," Professor Reeder Said

    Monash News, December 2003 Appointment Boosts Meteorology Leadership Briefly Mathematical Sciences Intemationally," Professor Reeder Said

    RESEARCH • SPECIAL FEATURE NEWS , _. ~ Genome solved t : " ;.,. 2003 News Under the . ~"' ..# - now for vaccine 3 \ ).. I Roundup 4/5 volcano 6 Expats come home we need you Australia is losing vita! 'hwnan capita!' because thousands ofyoung "Most people professionals who go overseas to want to work are not returning, a Monash academic asserts. come back, Professor Phyllis Tharenou,. of I but their Facing the future: Monash South Africa graduates (clockwise from top left) Mr Richard Zanner the Department of Management (BBusSys). Mr Douglas Minnaar (BComp). Mr Bradley Harrison (BComp). Mr Kai Grunwald (SBusSys). in the Faculty of Business and companies Ms Tracey-Leigh Wraight (BA). Ms Simanga Humphrey (BA). Ms Susan Pretto (BA). Ms Michelle Letzier Economics, said Australia is (BA). and Ms Louise Emanuel (BBusCom). experiencing the largest ever do not have emigration ofpeople aged between repatriation 21 and 34. It is estimated that one million Australians are currently policies to working overseas, and 350,000 of Monash South Africa them are hom Victoria. allow this. II "This exodus means we are - Professor Tharenou not returning the knowledge to Australia where it is needed to develop our own "My study has already found that most people students make history industries. This will harm our economy because want to come back, but their companies do not it will deprive us of vital talent for our country's have repatriation policies to allow this. Three years ago in South A&ica, a group of in the life of future prosperity," she said. "When an international firm has a young srudents took a chance and joined the country's theuaiversity Professor .Tharenou has completed a study, employee they know is highly disposed to an newest tertiary instirution, Monash South and, ofcourse, funded by an Australian Research Council (ARC) international career, they could target that person Africa (MSA).
  • Sir Howard Florey - Biography

    Sir Howard Florey - Biography

    Sir Howard Florey - Biography Sir Howard Florey – Biography The Nobel Prize in Physiology or Medicine Sir Howard Walter Florey was 1945 born on September 24, 1898, at Presentation Speech Adelaide, South Australia, the son Educational of Joseph and Bertha Mary Florey. His early education was at St. Sir Alexander Fleming Peter's Collegiate School, Adelaide, Biography Nobel Lecture following which he went on to Banquet Speech Adelaide University where he Documentary graduated M.B., B.S. in 1921. He Other Resources was awarded a Rhodes Scholarship to Magdalen College, Oxford, Ernst B. Chain leading to the degrees of B.Sc. and Biography M.A. (1924). He then went to Nobel Lecture Cambridge as a John Lucas Walker Banquet Speech Student. In 1925 he visited the United States on a Rockefeller Other Resources Travelling Fellowship for a year, returning in 1926 to a Fellowship at Gonville and Caius College, Cambridge, receiving Sir Howard Florey here his Ph.D. in 1927. He also held at this time the Freedom Biography Research Fellowship at the London Hospital. In 1927 he was Nobel Lecture appointed Huddersfield Lecturer in Special Pathology at Banquet Speech Cambridge. In 1931 he succeeded to the Joseph Hunter Chair of Pathology at the University of Sheffield. 1944 1946 Leaving Sheffield in 1935 he became Professor of Pathology and a Fellow of Lincoln College, Oxford. He was made an The 1945 Prize in: Physics Honorary Fellow of Gonville and Caius College, Cambridge in Chemistry 1946 and an Honorary Fellow of Magdalen College, Oxford in Physiology or Medicine 1952. In 1962 he was made Provost of The Queen's College, Literature Oxford.
  • Cortical Connections 2015

    Cortical Connections 2015

    Cortical Connections 2015 19th and 20th of March, 2015 Queensland Brain Institute Brisbane, Australia Program, Speaker Biographies, and Abstracts Programme Day 1 Thursday March 19 Programme Day 1 Thursday March 19 8:15AM Registration open Session 2: Genetics of cortical wiring disorders 8:45AM Welcome by Prof. Linda Richards Queensland Brain Institute 12:00– Prof. Elliott Sherr 1:00PM University of California, San Francisco Cerebral connectivity: from genes to cognition Session 1: Development of cortical wiring 1:00– Lunch at QBI 9:00– Prof. Roberto Lent 1:30PM 10:00AM Federal University of Rio de Janeiro 1:30– Distance plasticity - on connectomes Prof. Jozef Gécz 2:00PM University of Adelaide and dysconnectomes Protocadherin 19 and female limited 10:00– Dr Richard Leventer epilepsy and intellectual disability Session chairs 10:30AM Dr Jens Bunt Murdoch Childrens Research Institute, Melbourne 2:00– Agenesis of the corpus callosum and the Prof. Kathryn North and 2:30PM Director, Murdoch Childrens Research Institute, company it keeps Dr Peter Kozulin Session chairs Melbourne 10:30– Dr Ilan Gobius Learning disabilities in childhood – lessons from Prof. Stephen Williams and 11:00 AM Queensland Brain Institute Ms Laura Fenlon Active dendritic integration underlies circuit- 2:30– based neocortical computations Prof. Ingrid Scheffer 3:00PM The University of Melbourne, Florey Neurosciences 11:00 – Institute, Murdoch Childrens Research Institute, 11:30 AM Morning tea on the QBI terrace Melbourne Genetics of the epilepsies—framing cortical 11:30 AM– Prof. Linda Richards connections 12:00PM Queensland Brain Institute Development of the corpus callosum 3:00– 3:30PM Afternoon tea 3:30– Prof.
  • Penicillin: World War II Infections and Howard Florey

    Penicillin: World War II Infections and Howard Florey

    In Focus Penicillin: World War II infections and Howard Florey The results were dramatic – the control mice rapidly succumbed, while all of the treated mice survived. These results attracted great interest from the scientific and military communities because, if Ian Gust replicated in humans, the drug had the potential to influence the Department of Microbiology and outcome of WWII. Immunology University of Melbourne It took Florey and 16 colleagues several months to produce suffi- Parkville, Vic. 3010, Australia Tel: +61 3 8344 3963 cient material to treat a handful of patients. The team worked under Fax: +61 3 8344 6552 fi fi Email: [email protected] dif cult circumstances with a lack of funding and equipment; at rst penicillin was made using old dairy equipment. Hospital bedpans were later used to grow the mould and the liquid containing fi Howard Florey is celebrated for his major contributions to penicillin drained from beneath the growing mould and ltered the large-scale production of the fungal product, penicillin, through parachute silk. during World War II (WWII), leading to life-saving outcomes The first patient they treated was a policeman, in whom an infected for many more than those with war wounds. scratch had developed into a life threatening infection. He was given Howard Florey was born in South Australia in 1898. After studying penicillin, and within a day began to recover. Unfortunately Florey’s medicine at the University of Adelaide he was awarded a Rhodes team only had sufficient drug for 5 days of treatment and when Scholarship to work in Oxford under Sir Charles Sherrington.
  • Paediatric Epilepsy Research Report 2019

    Paediatric Epilepsy Research Report 2019

    Paediatric Epilepsy 2019 Research Report Inside Who we are The organisations and experts behind our research programme What we do Our strategy, projects and impact youngepilepsy.org.uk Contents Introduction 1 Who we are 2 Research Partners 2 Research Funding 4 Research Team 5 What we do 10 Programme Strategy 10 The MEG Project 12 New Research Projects 14 Research Project Update 21 Completed Projects 32 Awarded PhDs 36 Paediatric Epilepsy Masterclass 2018 37 Paediatric Epilepsy Research Retreat 2019 38 Research Publications 40 Unit Roles 47 Unit Roles in Education 49 Professional Recognition and Awards 50 Paediatric Epilepsy Research Report 2019 Introduction I am delighted to present our annual research report for the period July 2018 to June 2019 for the paediatric epilepsy research unit across Young Epilepsy, UCL GOS - Institute of Child Health and Great Ormond Street Hospital for Children. We have initiated 13 new research projects, adding to 20 active projects spanning the clinical, educational and social elements of paediatric epilepsy. We have published 110 peer-reviewed items of primary research and a further 54 chapters in books, reviews and commentaries of expert opinion. During this period, Young Epilepsy Chief Executive Carol Long caught the research bug and moved on to begin her PhD at Durham University. We welcomed our new Chief Executive, Mark Devlin at our Paediatric Epilepsy Research Retreat in January 2019. As an organisation, we are launching a new strategy This report features a spotlight on a truly which sets our research programme as one of innovative project which will change the UK’s the four key offers at Young Epilepsy, and we diagnostic and surgical evaluation imaging suite look forward to sharing our research more widely for childhood epilepsy.
  • Illustrations from the Wellcome Institute Library the Chain Papers*

    Illustrations from the Wellcome Institute Library the Chain Papers*

    Medical History, 1983, 27:434-435 ILLUSTRATIONS FROM THE WELLCOME INSTITUTE LIBRARY THE CHAIN PAPERS* THE three men who shared the Nobel Prize in October 1945 for their work on penicillin could scarcely have differed more in their backgrounds and characters. Fleming was sixty-four years old by then; the son of a Scottish farmer, he was a retiring man, not given to conversation. By contrast, Florey, then aged forty-seven, was the son of a wealthy Australian boot and shoe manufacturer; aggressively ambitious, his achievements and intellect were later to secure him the Presidency of the Royal Society. Then there was Chain - a mere thirty-nine years old - a Jewish refugee of Russian origin, who still had major work on penicillin ahead of him; his ambition was mixed with an independence and volubility that was to lead him into conflict with the scientific/medical establishment. Fleming has been the subject of many biographies, mostly hagiographical. Florey's role in the penicillin story was recently reassessed in Gwyn Macfarlane's excellent Howard Florey. The making ofa great scientist (Oxford University Press, 1979). Sir Ernst Boris Chain died in 1979, and his biography is being written by Ronald W. Clark. This, together with future research on Chain's papers, will enable a fuller assessment to be made of the role and character of the youngest of the three scientists. The Chain papers, recently given by Lady Chain to the Contemporary Medical Archives Centre, form an extensive collection of some sixty-nine boxes, comprising material from Chain's personal and professional life.
  • Speaker's Manuscript

    Speaker's Manuscript

    Nobel Prize Lessons 2018 Speaker’s manuscript – the 2018 Medicine Prize The Nobel Prize in Physiology or Medicine • The Nobel Prize in Physiology or Medicine is one of the five prizes founded by Alfred Nobel and awarded on December 10 every year. Before Alfred Nobel died on December 10, 1896, he wrote in his will that the largest part of his fortune should be placed in a fund. The yearly interest on this fund would pay for a prize given to “those who, during the preceding year, shall have conferred the greatest benefit to humankind.” Who is rewarded with the Medicine Prize? • The Nobel Prize in Physiology or Medicine is thus awarded to people who have either made a discovery about how organisms work or have helped find a cure for a disease. • This is May-Britt Moser, 2014 Nobel Laureate in Medicine. In 2005 she and Edvard Moser discovered a type of cell in the brain that is important for determining one's position. They also found that those cells cooperate with different nerve cells in the brain that help us to navigate. You can say that the Laureates discovered and explained a kind of GPS system in the brain. • Other Medicine Laureates include: • Francis Crick, James Watson and Maurice Wilkins, who received the 1962 Prize for their discoveries and descriptions about the structure of DNA molecules. • Alexander Fleming, Ernst Chain and Howard Florey, who received the 1945 Prize for the discovery of penicillin and its curative effects on bacterial diseases. Medicine Prize 2018 • The 2018 Nobel Prize is about a new way of treating cancer.
  • 2016 Annual Review a Summary of Our Year

    2016 Annual Review a Summary of Our Year

    2016 Annual Review A summary of our year Royal Society Te Apārangi 0 Contents Introduction from the President ............................................................................................................... 2 Explore ........................................................................................................................................................... 3 Increased funding allowed Marsden Fund to support more early-career researchers ............................. 3 Supporting established researchers to explore their area of expertise .................................................... 3 Supporting early career researchers to become leaders .......................................................................... 4 Supporting emerging researchers to develop their careers ...................................................................... 4 ORCID Consortium will help close the loop on New Zealand’s research system ....................................... 5 Powering Potential on climate change ...................................................................................................... 6 NZIFST/CREST Student Product Development Challenge .......................................................................... 6 Teachers in Industry .................................................................................................................................. 6 Science Teaching Leadership Programme ................................................................................................
  • Melbourne Neuroscience Institute 2017 Annual Report

    Melbourne Neuroscience Institute 2017 Annual Report

    Melbourne Neuroscience Institute 2017 Annual Report A © The Melbourne Neuroscience Institute Enquiries for reprinting information contained in this publication should be made through: [email protected] Every attempt has been made to ensure that the information in this publication was correct at the time of printing. Editor: Amy Bugeja Designer: External Relations 23201 For further information visit: www.neuroscience.unimelb.edu.au Contents Executive Summaries 02 Research 04 Engagement 32 Partnerships 45 Funding Initiatives 50 Governance 54 1 CHAPTER 1 Executive Summaries Message from the Director It is with great pleasure that we table the 2017 annual report for the Melbourne Neuroscience Institute (MNI). The MNI has now been extant for 8 years and during that time it has unwaveringly served to promote the Neurosciences and related disciplines at the University of Melbourne. This report serves to demonstrate both the current strength of Neuroscience research on campus and the role that MNI has played in fostering many of these activities. The spectrum of Neuroscience research conducted at this University is impressive and what is presented in this report is an important but, by necessity, a small proportion of the exciting work that is being conducted. What is very apparent is that much of the work relies on strong collaborative interactions and often those collaborative interactions span several faculties. I am particularly pleased to see this, reflecting that the promotion of Our international interface continues to strengthen. This is most interdisciplinarity that has been one of the key goals of MNI, apparent through our strong links with the Salpetriere in Paris and an outcome that we have been able to facilitate via our with the Hotchkiss Brain Institute in Calgary.