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New Flexible Tip Bougie Catheter for Difficult Airway Intubation. a Randomized, Crossover Pilot Study

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New Flexible Tip Bougie Catheter for Difficult Airway Intubation. a Randomized, Crossover Pilot Study Disaster and Emergency Medicine Journal 2019, Vol. 4, No. 2, 50–54 BRIEF REPORT DOI: 10.5603/DEMJ.2019.0010 Copyright © 2019 Via Medica ISSN 2451–4691 NEW FLEXIBLE TIP BOUGIE CATHETER FOR DIFFICULT AIRWAY INTUBATION. A RANDOMIZED, CROSSOVER PILOT STUDY Michael Frass1, Jacek Smereka2, Kurt Ruetzler3, Lukasz Szarpak4, Oliver Robak1 1Department of Medicine I, Medical University of Vienna, Vienna, Austria 2Department of Emergency Medical Service, Wroclaw Medical University, Wroclaw, Poland 3Departments of Outcomes Research and General Anesthesiology, Anesthesiology Institute, Cleveland Clinic, Cleveland, Ohio, USA 4Lazarski University, Warsaw, Poland ABSTRACT INTRODUCTION: The ability to protect the airway is one of the basic skills that medical staff should have, especially those working within the Emergency Medical Service or Emergency Department. Endotracheal intubation under medical emergency conditions based on direct laryngoscopy is not effective enough; this effect is additionally reduced in the case of the difficult airway resulting from reduced visibility of the en- trance to the glottis due to tongue or epiglottis oedema, trauma, etc. The aim of the study was to compare the intubation time and its effectiveness using two different stylets for difficult airway intubation. matERIAL AND METHODS: The study involved 37 nurses who participated in training on advanced life support procedures. The experiment was designed as a randomized, cross-over simulation study. During the training, participants were instructed to perform endotracheal intubation using the tested intubation methods and had 20 minutes of practical training during which they were able to intubate with the tested stylets under normal airway. In the study, participants performed endotracheal intubation using a laryngoscope with a Macintosh blade and a difficult airway Bougie stylet (ONTEX, Chennai, India), or the Flexible Tip Bougie (MDSS GmbH, Hannover, Germany), which was designed to allow to guide the distal end of the anteriorly and posteriorly to facilitate entry into the larynx. RESUlts: The effectiveness of the first intubation attempt using a standard Bougie stylet was 37.8%, and that of the new Bougie stylet was 51.4% (p = 0.037). The mean intubation time was 55 s (IQR; 34–65) vs. 37 s (IQR; 25–41) (respectively, p = 0.021). The median ease of intubation was 7 (IQR; 5–9) points for a standard Bougie stylet and 5 (2.5–7) 2 points for a new Bougie stylet (p = 0.018). CONCLUSIONS: In a simulation study, the use of Flextip Bougie by nurses compared to a standard Bougie stylet was associated with higher efficacy and shorter intubation times in difficult airway. KEY WORDS: endotracheal intubation; simulation, catheter, airway management, direct laryngoscopy Disaster Emerg Med J 2019; 4(2): 50–54 INTRODUCTION working within the Emergency Medical Service or The ability to protect the airway is one of the basic Emergency Department [1, 2]. In pre-hospital set- skills that medical staff should have, especially those tings, each endotracheal intubation is emergency ADDREss FOR CORRESPONDENCE: Lukasz Szarpak, Lazarski University, 43 Swieradowska Str., 02–662 Warsaw, Poland; e-mail: [email protected] 50 Copyright © 2019 Via Medica, ISSN 2451–4691 Michael Frass et al., New Flexible Tip Bougie catheter procedure so it is impossible to estimate the risk of analyzed the effectiveness of the first intubation complications during intubation, so each patient attempt as well as the time of the procedure. After should be treated as a patient with difficult airway intubation, the study participants evaluated the ease and caution should be exercised when securing the of the procedure using a 10-degree audio-visual airway [3]. Endotracheal intubation under medical scale, where ‘1’ was an easy procedure and ‘10’ emergency conditions based on direct laryngoscopy a difficult procedure. Statistical analysis of the ob- is not effective enough; this effect is additionally tained data was performed using Statistica 13.1EN reduced in the case of the difficult airway resulting (StatSoft, Tulus, USA). from reduced visibility of the entrance to the glottis The Statistica 13.3EN software (TIBCO Inc., Tulsa, due to the tongue or epiglottis oedema, trauma, OK, USA) was used for statistical analysis. Times need- etc. [4–6]. It is, therefore, crucial to seek new, more ed to archive a sufficient glottic view until insertion of effective endotracheal intubation techniques that the tracheal tube was compared using the Wilcoxon both facilitate the intubation process and shorten signed-rank test. To detect possible differences in the whole procedure. success rates for endotracheal intubation, the McNe- The aim of the study was to compare the intu- mar’s test was used. A p < 0.05 was considered as bation time and its effectiveness using two different statistically significant. All results are shown as medi- stylets for difficult airway intubation. an and interquartile range (IQR), mean and standard deviation (SD) or percentages (%). METHODS The study was designed as a prospective, rand- RESULTS omized, cross-over study and was conducted under The study involved 37 nurses, whose mean age was medical simulation conditions. The study protocol 42 ± 11 years, while the mean work experience was approved by the Institutional Review Board of was 12 ± 8 years. All persons participating in the the Polish Society of Disaster Medicine (Approval study declared their ability to endotracheal intuba- no: 21.03.2019.IRB). 37 nurses participating in tion based on direct laryngoscopy. advanced cardiovascular life support courses were The effectiveness of the first intubation attempt included in the study. Voluntary written informed using a standard Bougie stylet was 37.8%, and that consent was obtained from each participant. of the new Bougie stylet was 51.4% (p = 0.037). Before the survey was started, all participants The mean intubation time was 55s (IQR; 34–65) attended an airway management training course. vs. 37s (IQR; 25–41) (respectively, p=0.021; Fig. 3). During the training, participants were instructed to The median ease of intubation was 7 (IQR; 5–9) perform endotracheal intubation using the tested points for a standard Bougie stylet and 5 points intubation methods and had 20 minutes of practical (2.5–7) 2 points for a new Bougie stylet (p = 0.018; training during which they were able to intubate Fig. 4). with the tested stylets under normal airway. In the study, participants performed endotrache- al intubation using a laryngoscope with a Macintosh blade and a difficult airway Bougie stylet (ONTEX, Chennai, India), or the Flexible Tip Bougie (MDSS GmbH, Hannover, Germany), which was designed to allow to guide the distal end of the anteriorly and posteriorly to facilitate entry into the larynx (Fig. 1). SimMan 3G simulator (Laerdal, Stavanger, Nor- way) was used to simulate a patient requiring airway management. Next, the study participants had to perform intubation in difficult airway conditions, which was obtained by inflation of air the tongue until obtaining Cormack-Lehane Grade 3. Both the order of participants and the technique of endotra- cheal intubation were random (Fig. 2). The study FIGURE 1. New flexible tip bougie www.journals.viamedica.pl 51 DISASTER AND EMERGENCY MEDICINE JOURNAL 2019, Vol. 4, No. 2 Enrollment Assessed for eligibility (n = 37) Excluded (n = 0) • Not meeting inclusion criteria (n = 0) • Declined to participate (n = 0) • Other reasons (n = 0) Randomized (n = 37) Allocation Allocated start with exible tip bougie (n = 19) Allocated start with standard bougie (n = 18) • Received allocated intervention (n = 19) • Received allocated intervention (n = 18) • Did not receive allocated intervention (n = 0) • Did not receive allocated intervention (n = 0) Cross-over Allocated start with standard bougie (n = 19) Allocated start with exible tip bougie (n = 18) • Received allocated intervention (n = 19) • Received allocated intervention (n = 18) • Did not receive allocated intervention (n = 0) • Did not receive allocated intervention (n = 0) Analysis Analysed (n = 74) • Excluded from analysis (give reasons) (n = 0) FIGURE 2. Randomization flow chart FIGURE 3. Mean intubation time FIGURE 4. Mean ease of intubation DISCUSSION Tracheal intubation in emergency conditions is The study showed that nurses were able to perform a challenge for medical personnel [7]. Performed endotracheal intubation with Flexible Tip Bougie with a Miller or Macintosh blade laryngoscope in with higher efficacy than a standard difficult intu- many cases can be difficult to perform or completely bation stylet. ineffective. This is particularly the case when intuba- 52 www.journals.viamedica.pl Michael Frass et al., New Flexible Tip Bougie catheter tion is performed by people without direct laryngo- 7. Markic S. Endotracheal tube ETView as a tool for airway management. scopy experience [8–11], during cardiopulmonary Disaster and Emergency Medicine Journal. 2018; 3(4): 152–153, doi: resuscitation, when continuous chest compression 10.5603/demj.2018.0032. is performed [12–14], in the case of intubation of 8. Szarpak L, Karczewska K, Czyżewski Ł, et al. Airtraq Laryngoscope patients with immobilized cervical spine [15–17], or Versus the Conventional Macintosh Laryngoscope During Pediatric patients with difficult airways [18–20]. Intubation Performed by Nurses: A Randomized Crossover Manikin According to research by Bganabhai et al. Flex- Study With Three Airway Scenarios. Pediatr Emerg Care. 2017; ible -tipped bougie has been helpful during video- 33(11): 735–739, doi: 10.1097/PEC.0000000000000741, indexed laryngoscopic intubation in a patient with a base in Pubmed: 27228145. of tongue tumour [21]. In this study, both the intu- 9. Mason R, Latimer A, Vrablik M, et al. Teaching Flight Nurses Ultraso- bation time and the ease of the procedure were in nographic Evaluation of Esophageal Intubation and Pneumothorax. favour of using flexible tip bougies. Due to the fact Air Med J. 2019; 38(3): 195–197, doi: 10.1016/j.amj.2018.11.007, that flexible tip bougie is a relatively new device on indexed in Pubmed: 31122586. the medical market, there are no scientific reports 10.
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