Recombinant Human SIRPG/SIRPB2 Protein

Leader in Biomolecular Solutions for Life Science

Catalog No.: RP00614 Recombinant

Sequence Information Background

Species Gene ID Swiss Prot Signal-Regulatory Protein Gamma (SIRPG) is a member of the signal-regulatory Human 55423 Q9P1W8 protein (SIRP) family and alsobelongs to the immunoglobulin superfamily. SIRPG is detected in the liver, and at very low levels in the brain,heart, lung, pancreas, Tags kidney, placenta, and skeletal muscle. SIRPG is an immunoglobulin-like cell C-Fc surfacereceptor. On binding with CD47, SIRPG mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced Synonyms antigen-specific T-cell proliferation and costimulates T-cell activation.SIRPG as Signal-Regulatory Protein Gamma; receptor-type transmembrane glycoproteins is involved in the negative regulation SIRP-Gamma; CD172 Antigen-Like of receptortyrosine kinase-coupled signaling processes. Family Member B; Signal-Fegulatory Protein Beta-2; SIRP-b2; SIRP-Beta-2; CD172g; SIRPG; SIRPB2 Basic Information

Description Product Information Recombinant Human SIRPG/SIRPB2 Protein is produced by Human cells expression system. The target protein is expressed with sequence (Glu29-Pro360) of human Source Purification SIRPG/SIRPB2 (Accession #Q9P1W8) fused with an Fc tag at the C-terminus. HEK293 cells > 95% by SDS- PAGE. Bio-Activity

Endotoxin Storage < 1 EU/μg of the protein by LAL Store the lyophilized protein at -20°C to -80 °C for long term. method. After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week. Formulation Avoid repeated freeze/thaw cycles. Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation.

Reconstitution Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water.

Contact

www.abclonal.com Validation Data

Recombinant Human SIRPG/SIRPB2 Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.