Chronic Nephritis Is Not Often Seen. Arthritis, Gastro-Intestinal Symptoms

Total Page:16

File Type:pdf, Size:1020Kb

Chronic Nephritis Is Not Often Seen. Arthritis, Gastro-Intestinal Symptoms appeared so that between November 18 and December None of these studies, however, furnished more 15 he lost thirty-seven pounds in weight. Six months than indirect evidence of the influence which the high later his urine contained much less albumin and a few calory diet might exert on the natural history of casts and he looked very well. One and one half years typhoid fever. On account of the wide variations in later and three years later he was seen. The last the course of the disease in different seasons, such time his urine showed a very slight trace of albumin evidence can be obtained only from the study of a and a very rare hyaline cast. His blood pressure was series of cases extending over a number of years. normal and for two years he had been steadily at work A statistical study has therefore been undertaken of in a machine shop running a lathe and feeling per¬ the course of typhoid fever in patients on the high fectly well. calory diet and in an equal number of patients on diets Was this a case of nephritis with a complicating (milk, broths, egg albumin water) furnishing not more purpura or does it belong to the group I have been than from 1,000 to 1,500 calories a day. The num¬ discussing? I must confess I do not know. Abdomi¬ ber of cases available is not sufficiently large to justify nal pain of various types does occur often in typical comparison of the frequency of the rarer symptoms chronic nephritis without skin lesions and I usually and complications ; even with respect to the commoner call my students' attention to this as a type of symp¬ features of the disease, only tentative conclusions are tom in chronic nephritis, that often leads to diag¬ drawn unless the evidence is overwhelming. S nostic errors. On the other hand I am inclined to Material.—The material consisted of 444 patients, think that in many patients hematuria, albuminuria, half of them on the high calory diet and the other half and other renal disturbances occur as part of the dis¬ on a milk diet. All of the patients were treated on the ease entity here under consideration and that these second medical division of Bellevue Hospital except renal disturbances are due to kidney lesions similar forty-five of those on the milk diet. The majority of in nature to those occurring in the skin. In this sense the patients were under my personal care, thus elimi¬ the renal lesions are not truly those of nephritis. This nating differences in the course of the disease which probably explains why in these patients with seem¬ might be attributable to different methods of treatment ingly so severe a renal lesion progression into a true other than diet. The histories cover the years from chronic nephritis is not often seen. 1903 to 1914, inclusive. As far as possible, cases in corresponding years have been selected, but the use of CONCLUSIONS the high calory diet became so general throughout the There is a definite clinical 'intity in which with hospital about 1911 that, in order to complete the milk skin lesions of the erythema group (purpura, ery¬ series, it was necessary to utilize 113 histories from thema, urticaria, angioneurotic edema) visceral lesions 1903 to 1906, inclusive. occur as the result of the same type of lesion. The The histories were taken from the records seriatim. most common of these visceral manifestations are All patients were classified as casesîf~the hematuria and high calory arthritis, gastro-intestinal symptoms, attempt had been made to nourish them liberally, even various disturbances of renal function. The visceral if it failed or was only partially successful. disturbances occur unaccompanied by the skin lesions. A moderate number of histories were unsuitable for of the is The symptomatology group very complex analysis, the reasons being doubt as to the diagnosis, the the skin lesions a and without presence of at entrance into the hospital late in the disease, and death the cases in given time present great difficulties within a week of admission. Of the fatal cases diagnosis. excluded, three were on the high calory diet and twelve on milk. Fifty-five of the high calory, cases THE INFLUENCE OF THE HIGH CALORY were mild, 149 were severe, and eighteen were fatal. DIET ON THE COURSE OF Forty-four of the milk cases were mild, 104 were TYPHOID FEVER severe, and thirty-nine were fatal. Duration of the Disease.—There is no evidence to WARREN COLEMAN, M.D. indicate that the duration of the febrile period of the NEW YORK disease or the range of temperature is affected by diet The various studies concerning the high calory diet except, perhaps, that long recrudescences are rarer in which have been carried out in Bellevue dur- patients who are well nourished. Hospital The total duration of the is the last ten years, have established beyond question disease, however, short¬ ing in some months. That the the value to the individual typhoid patient of the ened, instances, by is, long so have not been maintenance of an optimal state of nutrition.1 Con- convalescences, formerly common, observed. The records with to convalescence trary to the common belief, it was found that large respect of selected foods could be taken without are by no means complete, but a number of patients quantities have back to the from time to time. disturbance of Likewise, it was found that reported hospital digestion. All of them have stated that felt is absorbed the typhoid patient practically as they perfectly well food by and were able to follow their as healthy men. Under the high calory physically occupations completely by of the were even a diet the febrile loss of is reduced to a (many patients laborers) within body protein short time after their minimum or altogether prevented. Investigations of discharge. the total metabolism of have shown Condition of the Mouth.—While it is recognized typhoid patients that the condition the that large amounts of food are consumed with avidity, of mouth, including the tongue, in fever is on the amount of atten¬ any excess over the immediate needs being laid by for typhoid dependent on the be future use. tion bestowed it by nurse, it may stated that the mental condition of patients who are well nour¬ Read before the Section on Practice of Medicine at the Sixty\x=req-\ ished is so good that they themselves their Eighth Annual Session of the American Medical Association, New keep York. June, 1917. mouths clean. The only histories containing notes to 1. For the bibliography of the papers by Drs. Shaffer and Du Bois, the effect that the and were in poor condi¬ Mr. Gephart, and the author, see Arch. Int. 1914, p. 168; lips tongue Med., August, were May, 1915, pp. 882, 887. tion found in the milk group. Downloaded From: http://jama.jamanetwork.com/ by a University of Manitoba User on 06/14/2015 Nausea and Vomiting.—Nausea and followed the attempt to increase the food beyond occurred in 19.3 per cent, of the high calory cases and 1,000 to 1,500 calories, in spite of frequent alteration in 22.6 per cent, of the milk cases. The difference is of the proportions of protein, fat, and carbohydrate. negligible. Nausea and vomiting were more frequent Reference may be made in this connection to 3 among the earlier high calory cases when the diet was Torrey's study of the intestinal flora of some of the limited to milk, cream, lactose, and eggs ; these symp¬ high calory cases of this series and of other cases on a toms became less common as other articles of food milk diet. Torrey found that patients who were able were added to the diet. Nausea and vomiting did not to take large amounts of food without digestive dis¬ always coexist in' the same patient. Lactose at times turbances possessed a flora dominated by the Bacillus caused vomiting without nausea. Most often nausea acidophilus, and that patients with an initial putre¬ and vomiting followed attempts to increase the food factive flora were capable of developing a favorable too rapidly or when the food mixtures were too rich. fermentative flora, with disappearance of tympanites Some patients vomited the high calory diet and milk or diarrhea, under the influence of the diet. Excep¬ indifferently. A few patients had persistent and un¬ tionally, the putrefactive type of flora persisted in spite controllable vomiting due either to recent excesses in of alteration of the diet—these were the patients who alcohol or to the disease per se. could not be liberally nourished. The therapeutic Tympanites and Diarrhea.—Though often asso¬ application of these results was at once apparent and ciated, these did not always occur together. Tym¬ at my request Dr. Torrey prepared a pure culture of panites occurred in 17.6 per cent, of the high calory Bacillus acidophilus for administration to typhoid cases and in 31.5 per cent, of those on milk. Extreme patients. The bacillus was used first for patients enter¬ grades of tympanites were rarely observed among the ing the hospital with tympanites and diarrhea in order high calory cases. Diarrhea occurred in 16.2 per cent, to hasten the transformation of the flora; later it was of the high calory cases and in 48.6 per cent, of those given more or less as a routine measure. The results on milk. Temporary diarrheas of one to several days' have been satisfactory. duration have been included in the percentage for the Through the investigations of Torrey, and of Hull high calory cases but not in that for the milk cases.
Recommended publications
  • Post-Operative Hæmatemesis, with Notes of Eleven Cases
    POST-OPERATIVE HiEMATEMESIS, WITH NOTES OF ELEVEN CASES. By Robert Purves, M.B., F.R.C.S.Ed., Tutor in Clinical Surgery University of Edinburgh, and Assistant-Surgeon Deaconess Hospital. Attention was at first directed to the occurrence of post-operative hrematemesis by von Eiselsberg, who recorded eight cases at the German Surgical Congress of 1899. Of thirty-seven cases since recorded, I have obtained some particulars in twenty-nine. Twenty-four followed abdominal operations?including, hernia (eight cases), gall-bladder (three cases), appendicitis (six cases); also after ovariotomy, tuberculous peritonitis, intestinal obstruction, exploration for stab of abdomen, and exploratory incision in the iliac fossa. Of the five other cases, two followed excision of the rectum; one, suprapubic lithotomy; and one, removal of cancer of the palate. Htematemesis has also followed infection of the urinary tract. The following eleven cases have been collected from the wards of the Eoyal Infirmary, and for permission to report them I am indebted to the courtesy of Professors Annan- dale and Chiene and Dr. MacGillivray. Case 1. Mrs. 3v., ait. 53 (Prof. A.), had an umbilical hernia for twe \e years, which gave rise to periodic attacks of pain, vomiting, and constipation ; no vomiting at present. Previous history was negative.? Operation, September 9, 1901.?The sac contained a large loop of small intestine and a considerable mass of adherent omentum. During the operation the bowel -\vas perforated; little or no escape of contents occurred, and the opening was at once sutured; part of the omentum was removed. There was no chloroform sickness. The first hsemate- mesis occurred thirty hours after operation, when she suddenly vomited a large quantity of coffee-ground fluid.
    [Show full text]
  • Having Thus Cited the Peculiarities of Each of These Toms And
    tion, while at other times only a few or so accompanied each EXTRAUTERINE PREGNANCY stool. In addition to symptoms previously mentioned, each of his attacks was preceded for 48 hours by sinking, depressed DISCHARGE OF FETUS BY RECTUM ; feelings, accompanied by burning, internal, colicky pains near PELVIC ABSCESS; INTESTINOVAGINAL FISTULA; GENERAL the region of the umbilicus. These symptoms, to him signifi¬ ADHESIVE PERITONITIS; PHLEBITIS OF BOTH cant of the approaching expulsion of maggots, loss of appetite, LEGS ; RECOVERY and ushered the The nausea, colic, diarrheic actions, in attack. J. R. LAUGHLIN, M.D. first loose stool contained the majority of the larva?, all being HAGEESTOWN, MU. expelled in 3 or 4 stools. After this the diarrhea, burning colic, nausea and depression subsided. His life habit had been Patient.—Mrs. J. B., aged 24; married six years; no children. to be slow at stool and always to defecate in the horse stable, Present Illness.—She had missed two periods and was sud¬ if possible. denly seized with severe pain and cramps in right side, fol¬ Management and Course.—My injunction to him to quit the lowed by a bloody discharge which had continued three weeks, use of the horse stable as a privy and to use a closed vessel, when I first saw her, June 8, 1908. caused a cessation of his infections from July, 1908, until Examination.—The uterus was slightly enlarged and firmly August, 1909, when he reported the return of the maggot and fixed; there was a slight bloody discharge from the cervix. return to his horse stable Another pleaded guilty to a practice.
    [Show full text]
  • Acute Appendicitis and Homoeopathy
    ACUTE APPENDICITIS AND HOMOEOPATHY © Dr. Rajneesh Kumar Sharma MD (Homoeopathy) Dr. (Km) Ruchi Rajput BHMS Homoeo Cure Research Centre P. Ltd. NH 74- Moradabad Road Kashipur (UTTARANCHAL) - INDIA Ph- 09897618594 E. mail- [email protected] DEFINITION Acute inflammation of the appendix BACKGROUND Appendicitis is a common and urgent surgical illness with variable manifestations, generous overlap with other clinical syndromes, and significant morbidity, which increases with diagnostic delay. No single sign, symptom, or diagnostic test accurately makes the diagnosis of appendiceal inflammation in all cases. PATHOPHYSIOLOGY Obstruction of the appendiceal lumen is the primary cause of appendicitis. Obstruction of the lumen leads to distension of the appendix due to accumulated intraluminal fluid. Ineffective lymphatic and venous drainage allows bacterial invasion of the appendiceal wall and, in advanced cases, perforation and spillage of pus into the peritoneal cavity. MORTALITY/MORBIDITY Overall mortality rate of 0.2-0.8% is attributable to complications of the disease rather than to surgical intervention. Mortality rate rises above 20% in patients older than 70 years, primarily because of diagnostic and therapeutic delay. Perforation rates are higher in patients younger than 18 years and in patients older than 50 years, possibly because of delays in diagnosis. Appendiceal perforation is associated with an increase in morbidity and mortality rates. SEX Incidence of appendicitis is approximately 1.4 times greater in men than in women. AGE Incidence of appendicitis gradually rises from birth, peaks in the late teen years, and gradually declines in the geriatric years. Although rare, cases of neonatal and even prenatal appendicitis have been reported. HISTORY Variations in the position of the appendix, age of the patient, and degree of inflammation make the clinical presentation of appendicitis notoriously inconsistent.
    [Show full text]
  • Primary Angiosarcoma of the Small
    Ni et al. World Journal of Surgical Oncology 2013, 11:242 http://www.wjso.com/content/11/1/242 WORLD JOURNAL OF SURGICAL ONCOLOGY CASE REPORT Open Access Primary angiosarcoma of the small intestine with metastasis to the liver: a case report and review of the literature Qingqiang Ni1, Dong Shang1*, Honghao Peng1,2, Manish Roy1,3, Guogang Liang1, Wei Bi1 and Xue Gao4 Abstract Angiosarcoma is a rare disease with a poor prognosis; significantly, patients with intestinal angiosarcomas who survive over 1 year after diagnosis are extraordinarily rare. This article describes the case of a 33-year-old gentleman who presented with abdominal pain of 4 months duration, which had increased in severity 2 weeks prior to presentation. After a complicated diagnostic and therapeutic process, the diagnosis of primary angiosarcoma of the small intestine with metastasis to the liver was made by pathological and immunohistochemical examinations. We reviewed previous cases of angiosarcoma described in the English literature to determine their risk factors, diagnosis and treatment, and we found that angiosarcoma is extremely rare, especially in the small intestine. To the best of our knowledge, this may be the youngest case of primary angiosarcoma of the small intestine with metastasis to the liver reported in the English literature. Keywords: Small intestine, Primary angiosarcoma, Hepatic metastasis Background in the left lower quadrant of the abdomen, which had Angiosarcomas, which account for only 1 to 2% of all soft worsened in the last 2 weeks before presentation. tissue sarcomas, are rare malignant tumors of endothelial Four months ago, the patient began experiencing ab- origin [1,2].
    [Show full text]
  • Historic, Archived Document
    Historic, archived document Do not assume content reflects current scientific knowledge, policies, or practices. ^ I :'3 T? •\~F?' V] 17 "1 ' ' t-; T[) | f 'k NOV ?/. °no ir \ Issued November 24, 1909. U. S. DEPARTMENT OF AGRICULTURE, BUREAU OF ANIMAL INDUSTRY.—CIRCULAR 68 (Revised). A. D. MELVIN, CHIEF OF BUREAU. l > DISEASES OF THE STOMACH AND BOWELS OF CATTLE.® By A. J. MURRAY, M. R. C. V. S. [Revised in 1904 by Leonard Pearson, V. M. D., and in 1908 by R. W. Hickman, V. M. D.] ACUTE TYMPANITES (HOVEN, OR BLOATING). This disease is characterized by swelling of the left flank, and is caused by the formation of gas in the rumen, or paunch. Causes,—Tympanites may be caused by any kind of food which pro- duces indigestion. When cattle are first turned into young clover they eat so greedily of it that tympanites frequently results; turnips, potatoes, and cabbage may also cause it; middlings and corn meal also frequently give rise to it. In this connection it may be stated that an excessive quantity of any of the before-mentioned foods may bring on this disorder, or it may not be due to excess, but to eating too hastily. Sometimes the quality of the food is at fault. Grass or clover when wet by dew or rain frequently disorders digestion and brings on tympanites; frozen roots or pastures covered with hoar frost should also be regarded as dangerous. When food has been eaten too hastily, or when it is cold and wet, the digestive process is imperfectly performed, and the food contained in the paunch fer- ments, during which process large quantities of gas are formed.
    [Show full text]
  • DIETARY FACTORS INFLUENCING ENTERIC DISORDERS of RABBITS Redacted for Privacy Abstract Approved: Peter R
    AN ABSTRACT OF THE THESIS OF MARK A. GROBNER for the degree of MASTER OF SCIENCE in ANIMAL SCIENCE presented on May 6, 1985 . Title: DIETARY FACTORS INFLUENCING ENTERIC DISORDERS OF RABBITS Redacted for Privacy Abstract approved: Peter R. Cheeke An extensive literature review into the causes and controls of diarrhea was followed by three weanling rabbit performance trials to examine the influence of dietary modifications on diarrhea in the rabbit. In the first set of experiments, the ion exchangers clinoptilolite (0,1.5 and 3.0%) and sodium bentonite(0 and 5.0%) were added to a low fiber (20% alfalfa) and high fiber (54% alfalfa) diet to examine performance and mortality of weanling rabbits. Gains, intakes, feed efficiencies and mortalities did not differ between clinoptilolite or bentonite levels. For both alfalfa levels, clinoptilolite added at 3.0% reduced mortality by 50% over the controls. Bentonite addition slightly depressed gains and intake with an increase in mortality. Rabbits preferred the non- bentonite diets 2:1 for the low fiber and 5:1 for the high fiber diets in a two choice feed preference test. In the second set of experiments, the effects of dietary alfalfa level and supplementation with copper sulfate (Cu) or oxytetracycline (TM-10) on the growth rate, feed conversion, mortality and tissue accumulation of Cu were examined. The inclusion of Cu with or without TM-10 had no effect on gains, feed efficiencies or mortality. Copper sulfate fed at 0, 50, 100, 250, or 500 ppm supplemental Cu had no effect on gains, feed efficiencies or mortality.
    [Show full text]
  • Flatulent Colic, Wind Colic, Or Tympanites
    50 diagnostic symptoms are the spasms are int.ermittent, not con­ 'Stant, and the pulse and breat,hing become normal, during the in­ tervals between t.he spasms. Treatment.-Give an anti-spasmodic, of which there Me many highly recommended for this complaint, such as (a) laudanum, 1, .ounce, spirits of nitrous ether, 1 ounce; water, half a pint; (b) -chloral hydra.te, 1 ounce in half a pint of water; or (c) extract 'Of belladonna, 1 drachm, sulphuric ether, 1 ounce, in half a pint of water. Either of these ma.y be repea.t-ed every two. hoW's. But if the first does not give r~lief, give a pint of raw linseed oil to remove the irritant, or preferably, as the first dose administer laudanum 2 ounces, turpentine 2 ounces, raw linseed Qiil one pint. In bad cases give repeated injections Qif warm water and soap, and :apply hot fomentations to the abdomen. FLATULENT COLIC, WIND COLIC, OR TYMPANITES. Oause3.-Indiges.tion, new forage, or my sudden change of food, green food very often produces it, and ravenous feeding after a long fast. ~Y1nptoms.-A dull, constant abdomina.l pain accompanied by & fulness of the abdomen, which has a. drum like sound on being struck, the horse paws with his fore feet occasiona.lly, and moves about uneasily, but when the swellmg of the abdomen increases, the a.nimal becomes greatly distressed, breathing becomes quick and oppressed, perspiration breaks .out· allover the body, trem­ bling of the muscles o·f the fO're quarten, frequent sighing, and if not relieved, he will manifest great distress and stagger about, until he fina.lly plunges forward and dies suddenly.
    [Show full text]
  • Clinical Lecture Some Children It Becomes Excessive, So Much So As to Cause Permanent Dyspnoea
    THE LANCET, JANUARY 1, 1881. more or less tympanites, sometimes associated with a little ascites. The tympanites usually remains moderate, but in Clinical Lecture some children it becomes excessive, so much so as to cause permanent dyspnoea. The ascites of the onset is small in TUBERCULAR PERITONITIS IN CHILDREN. quantity, and mostly goes away in a few weeks. After- wards the indurations which I spoke of begin to appear. Delivered at St. Bartholomew’s Hospital, Nov. 5th, 1880, 2. The onset is sometimes sudden, and attended by very great tympanites. The tympanites is sometimes the only BY SAMUEL GEE, M.D., F.R.C.P. LOND., abdominal symptom. Sometimes it is associated with PHYSICIAN TO THE HOSPITAL. vomiting. And sometimes there are also all the signs of acute gastro-enteritis. In my lecture on tympanites last are three kinds of tubercular abdo- session I narrated a case of this kind-a child suddenly GENTLEMEN,—There attacked infantile violent minal disease occurring in children: chronic peritonitis, by cholera; vomiting and purging, with collapse, algidity, and tympanites. This was the be- decay of the mesenteric glands, and ulceration of the in- ginning of chronic tubercular peritonitis. testines. These diseases are sometimes associated in dif- III. COURSE OF THE DISEASE. ferent ways, sometimes they happen each alone by itself. the chronic will most They constitute a condition which the common people call Suppose peritonitis established, you " be able to detect one or other of the of the bowels," this term also likely pathognomonic consumption although which I at the I will now includes the chronic enteritis which is not tubercular.
    [Show full text]
  • Preceding the Onset of Acute Symptoms. Although The
    779 grain of atropine was administered subcutaneously, andi at the operation. The opening into the parietal peri- soon as she was placed in bed she was surrounded by lie toneum was situated above the crest of the ilium, and water bottles and enveloped in warm blankets. had quite firm margins. So far as I can see, it For the first few days nutrient injections were adminiis- was a purely abnormal internal hernia. The whole of tered. Convalescence was somewhat delayed by a sha),rp the circumference of the bowel was not involved ; it attack of bronchitis, which came on towards the end of tltie would therefore come under the class described as Richter’s first week. She was discharged cured at the end of a rnontl.h. hernia in an abnormal position, the cause of the obstruction The temperature was perfectly normal for four days aft;erI being apparently an acute kink in the gut owing to the the operation, but on the fifth day, owing to the attackofI bowel being fixed at its circumference, and to paralysis of the bronchitis, it rose to 102°, subsiding, however, to tlhe muscular coat at the obstructed spot. It is interesting to normal again in two days. The bowels acted twice on tl] note that, although the bowel was ruptured on being with- fourth day, and again on the sixth. Vomiting entirel drawn from its abnormal position, careful stitching by ceased after the operation. She is now quite well. H(er Lembert’s sutures completely and effectually occluded the recovery was owing in a great measure to the careful afte:r- opening, and that the bowels were moved naturally within treatment and to the skilful nursing which she received b four days.
    [Show full text]
  • Addition to the Above Precautions, to Fortify the Resisting Tion of Water Per Rectum
    848 disorder. The acrid mucus, a free secretion of which is is, however, often necessary in recommending this step to one of the ordinary phenomena of the catarrhal state, is a parents. Mothers are apt to take fright at the very mention constant cause of fermentation and acidity. It very quickly of cold water; and it is true that in the case of weak children induces an acid change in the more fermentable articles of reaction is difficult to establish, so that a cold bath given in food. Therefore, if the stomach be oppressed by sour matters, the ordinary way would not be attended with benefit. There shown by uneasiness at the epigastrium, or sour smell from is, however, a method by which the most delicate child may the breath, and a feeling of nausea, immediate benefit will take a perfectly cold bath with safety and advantage. The be derived from an emetic dose of ipecacuanha wine. After- method consists in first stimulating the skin by friction, so wards a draught, composed of tincture of nux vomica, with as to enable the body to resist the shock of the cold douche, bicarbonate of soda, in water sweetened with spirits of and then in lessening the shock itself by placing the patient chloroform, taken two or three times in the day, will soon in hot water. Thus, if a child on rising from its bed be well restore the gastric mucous membrane to a healthy condition. shampooed over the whole body, but especially over the Strong purgatives are to be avoided, but as there is usually back and spine, and be then made to sit in a few inches of constipation in these cases, an occasional mild aperient will quite hot water, a good douche of cold salt water over the be required, such as compound liquorice powder or castor shoulders will have a highly invigorating effect, and be oil.
    [Show full text]
  • BIOCHEMICAL DISTURBANCES in EARLY LIFE by R
    Postgrad Med J: first published as 10.1136/pgmj.31.357.345 on 1 July 1955. Downloaded from 345 BIOCHEMICAL DISTURBANCES IN EARLY LIFE By R. H. WILKINSON, M.D. Department of Chemical Pathology, Th? Hospitalfor Sick Children, Great Ormndi Street, London Biochemical changes occur in a wide range of continue with periods of remission until dehydra- diseases in paediatric practice. It is amazing what tion becomes marked. When examined, the child tremendous deviations from normality are com- shows no characteristic clinical features. The patible with life. This section will be confined to weight is below normal. The child is listless, the use of chemical aids in the differential diagnosis muscle tone is poor and the signs of dehydration of a difficult problem in infancy, that of failure to are seen. Radiography may show medullary renal thrive. The differential diagnosis ranges from calcification. A specimen of urine may contain maternal mismanagement to galactosaemia. some protein, white cells and pathogenic organ- Causes of failure to thrive in early life are: isms, but not enough to suggest a severe urinary I. Nutritional, e.g. feeding technique and in- infection. The reaction of the urine may be acid adequate quantity or quality of food. if the child is dehydrated, but after this has been 2. Infective, e.g. gastro-enteritis, miliary tubercu- corrected the urine is alkaline or neutral. The keyby copyright. losis and otitis media. to the diagnosis is the finding of a plasma bicar- 3. Anatomical abnormalities, e.g. hiatus hernia, bonate less than i8 m.Eq./l. together with an obliteration of bile ducts and urethral obstruction.
    [Show full text]
  • Abdominal Distension and Bloating
    Abdominal Distension and Bloating Color index Important: Red Further explanation. Editing link Done by : Maram Alaqel Overview : Causes of Generalized abdominal distension (6Fs): ★ Fetus : - Pregnancy is the most common cause of abdominal distension. - Features: smooth firm dull swelling arising from the pelvis. - On Examination: on bimanual examination the mass cannot be moving independently from the cervix + cervix is soft and .difficult to diagnose in first 20 weeks ,(ﻣﺗﺳﻊ) patulous * DO NOT SQUEEZE AN ENLARGED UTERUS > CAN INDUCE LABOR OR ABORTION * ★ Flatus - Gas in the intestinal (Tympanites) - Early stage: localized distension related to one part (epigastrium if distended stomach OR right iliac fossa if distended cecum). - Late stage: all abdomen distended. - On examination: No palpable surface or edge/ Hyperresonance (other causes such as : Acute dilatation of the stomach, mechanical intestinal obstruction, paralytic ileus, aerophagia (air swallowing) and massive amounts of free gas from a perforation) Visible peristalsis (in case of obstruction) / Hyperactive bowel sounds. / Succussion splash (gastric distension caused by pyloric stenosis): Shaking the patient ★ Fat - Rarely causes distension, makes the patient pot-bellied - Causes of large fat abdomen: 1-thick layer of subcutaneous fat 2-excess fat in the omentum and mesentery. - On Examination: Obvious deposition in the lower half of the abdomen. - Pot-bellied: An excess of visceral fat is known as central obesity, the “pot belly” or “beer belly” effect. ★ Feces - Can be distension or a mass, the colon can become grossly distended with feces as a result of a mechanical obstruction or chronic constipation. - Causes: Hirschsprung’s disease, chronic intestinal obstruction, chronic constipation and antidepressant drugs. - On history: Bowel habits, complain of diarrhea (its actually spurious diarrhea*).
    [Show full text]