PRODUCT DATA SHEET Bioworld Technology,Inc.

EIF3G polyclonal antibody

Catalog: BS71416 Host: Rabbit Reactivity: Human,Mouse,Rat

BackGround: Purification&Purity: Component of the eukaryotic The antibody was affinity-purified from rabbit antiserum 3 (eIF-3) complex, which is required for several steps in by affinity-chromatography using epitope-specific im- the initiation of synthesis. The eIF-3 complex as- munogen and the purity is > 95% (by SDS-PAGE). sociates with the 40S and facilitates the re- Applications: cruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi WB 1:200 - 1:2000 and eIF-5 to form the 43S pre-initiation complex (43S Storage&Stability: PIC). The eIF-3 complex stimulates mRNA recruitment Store at 4°C short term. Aliquot and store at -20°C long to the 43S PIC and scanning of the mRNA for AUG term. Avoid freeze-thaw cycles. recognition. The eIF-3 complex is also required for dis- Specificity: assembly and recycling of post-termination ribosomal EIF3G polyclonal antibody detects endogenous levels of complexes and subsequently prevents premature joining EIF3G protein. of the 40S and 60S ribosomal subunits prior to initiation. DATA: This subunit can bind 18S rRNA. In case of FCV infec- tion, plays a role in the ribosomal termination-reinitiation event leading to the translation of VP2. Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Molecular Weight: ~ 42 kDa Western blot analysis of extracts of various cells, using EIF3G antibody. Swiss-Prot: Note: O75821 For research use only, not for use in diagnostic procedure.

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