International Journal of Molecular Sciences Review Reptiles in Space Missions: Results and Perspectives Victoria Gulimova 1,*, Alexandra Proshchina 1 , Anastasia Kharlamova 1 , Yuliya Krivova 1, Valery Barabanov 1, Rustam Berdiev 2, Victor Asadchikov 3 , Alexey Buzmakov 3 , Denis Zolotov 3 and Sergey Saveliev 1 1 Research Institute of Human Morphology, Ministry of Science and Higher Education RF, Tsurupi street, 3, 117418 Moscow, Russia;
[email protected] (A.P.);
[email protected] (A.K.);
[email protected] (Y.K.);
[email protected] (V.B.);
[email protected] (S.S.) 2 Research and Educational Center for Wild Animal Rehabilitation, Faculty of Biology, M.V. Lomonosov Moscow State University, Leninskie Gory, 1/12, 119899 Moscow, Russia;
[email protected] 3 Shubnikov Institute of Crystallography of FSRC “Crystallography and Photonics”, Russian Academy of Sciences, Leninsky Ave, 59, 119333 Moscow, Russia;
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[email protected] (D.Z.) * Correspondence:
[email protected]; Tel.: +7-916-135-96-15 Received: 7 May 2019; Accepted: 17 June 2019; Published: 20 June 2019 Abstract: Reptiles are a rare model object for space research. However, some reptile species demonstrate effective adaptation to spaceflight conditions. The main scope of this review is a comparative analysis of reptile experimental exposure in weightlessness, demonstrating the advantages and shortcomings of this model. The description of the known reptile experiments using turtles and geckos in the space and parabolic flight experiments is provided. Behavior, skeletal bones (morphology, histology, and X-ray microtomography), internal organs, and the nervous system (morphology, histology, and immunohistochemistry) are studied in the spaceflight experiments to date, while molecular and physiological results are restricted.