C5 (Human) ELISA Kit . [provided by RefSeq]

Catalog Number: KA2114 References: 1. C5a/C5aR pathway is essential for the pathogenesis Regulatory Status: For research use only (RUO) of murine viral fulminant hepatitis via potentiating Fgl2/fibroleukin expression. Xu GL, Chen J, Yang F, Li Product Description: C5 (Human) ELISA Kit is a GQ, Zheng LX, Wu YZ Hepatology. 2014 sandwich enzyme immunoassay for the quantitative Jul;60(1):114-24. doi: 10.1002/hep.27114. Epub 2014 measurement of human C5. May 28.

Calibration Range: 0.156 to 10 ng/mL

Reactivity: Human,Monkey

Applications: Quant (See our web site product page for detailed applications information)

Protocols: See our web site at http://www.abnova.com/support/protocols.asp or product page for detailed protocols

Storage Instruction: Store components of the kit at 4°C or -20°C as described in the protocol.

Entrez GeneID: 727

Gene Symbol: C5

Gene Alias: CPAMD4, FLJ17816, FLJ17822, MGC142298

Gene Summary: The encoded by this gene is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components. Mutations in this gene cause deficiency, a disease where patients show a propensity for severe recurrent infections. Defects in this gene have also been linked to a susceptibility to liver fibrosis and to

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