Sipeimine-Producing Endophytic Fungus Isolated from Fritillaria Ussuriensis Hong Yin* and Juan-Li Chen
Total Page:16
File Type:pdf, Size:1020Kb
Load more
Recommended publications
-
ZANCO Journal of Pure and Applied Sciences Antioxidant, and Antimicrobial Activities of Phenolic and Flavonoid Rich Medicinal Pl
ZANCO Journal of Pure and Applied Sciences The official scientific journal of Salahaddin University-Erbil ZJPAS (2018), 30 (5); 1-16 http://dx.doi.org/10.21271/ZJPAS.30.5.1 Antioxidant, and Antimicrobial Activities of Phenolic and Flavonoid Rich Medicinal Plants (Fritillaria zagrica and Tulipa kurdica) Bulbs Collected in Kurdistan Region of Iraq Mukhlis H. Aali1, Nadhum J. Ismaiel2, Fadzilah A. Abdul Majid3 1Department of Biology, College of Science, University of Salahaddin, Erbil, Kurdistan Region, Iraq 2Department of Biology, College of Education, University of Salahaddin, Erbil, Kurdistan Region, Iraq 3Institute of Marine Biotechnology, University Malaysia Terengganu, 21300 Kuala Terengganu, Terengganu, Malaysia. A R T I C L E I N F O A B S T R A C T Article History: Fritillaria zagrica and Tulipa kurdica had been used as traditional herbal Received: 06/05/2018 remedies since antiquity to treat human diseases in the Kurdistan region of Iraq. Accepted: 10/07/2018 This is the first report and conceive to analyze these two medicinal plants based. Published: 28/10 /2018 Methanol, 80% ethanol and aqueous extracts of two medicinal plants (Fritillaria Keywords: zagrcia and Tulipa kurdica) were evaluated for their antibacterial activity and Fritillaria zagrica, antifungal activities. We have quantified the total phenolic (TPC) and flavonoid Tulipa kurdica, (TFC) contents and their relation to antioxidants (ABTS) [2,2’-azinobis-(3- Antioxidant, ethylbenzothiazoline-6-sulfonate) and 2,2′-diphenyl-1 picryl hydrazyl Antimicrobial Activity, (DPPH)scavenging free radicals in a dose dependent method. Results showed that TPC, F. zagrica and T. kurdica bulb extractions by using different solvents exhibited TFC. -
The Complete Chloroplast Genome Sequences of Fritillaria Ussuriensis Maxim
molecules Article The Complete Chloroplast Genome Sequences of Fritillaria ussuriensis Maxim. and Fritillaria cirrhosa D. Don, and Comparative Analysis with Other Fritillaria Species Inkyu Park 1, Wook Jin Kim 1, Sang-Min Yeo 1, Goya Choi 1, Young-Min Kang 1, Renzhe Piao 2 and Byeong Cheol Moon 1,* 1 K-Herb Research Center, Korea Institute of Oriental Medicine, Daejeon 305-811, Korea; [email protected] (I.P.); [email protected] (W.J.K.); [email protected] (S.-M.Y.); [email protected] (G.C.); [email protected] (Y.-M.K.) 2 Department of Agronomy, Yanbian University Agriculture College, Yanji 133002, China; [email protected] * Correspondence: [email protected]; Tel.: +82-42-868-9530 Academic Editor: Derek J. McPhee Received: 6 March 2017; Accepted: 10 June 2017; Published: 13 June 2017 Abstract: The genus Fritillaria belongs to the widely distributed Liliaceae. The bulbs of Fritillaria, F. ussuriensis and F. cirrhosa are valuable herbaceous medicinal ingredients. However, they are still used indiscriminately in herbal medicine. Identification and molecular phylogenic analysis of Fritillaria species are therefore required. Here, we report the complete chloroplast (CP) genome sequences of F. ussuriensis and F. cirrhosa. The two Fritillaria CP genomes were 151,524 and 151,083 bp in length, respectively, and each included a pair of inverted repeated regions (52,678 and 52,156 bp) that was separated by a large single copy region (81,732 and 81,390 bp), and a small single copy region (17,114 and 17,537 bp). A total of 111 genes in F. -
Ornamental Plants in Different Approaches
Ornamental Plants in Different Approaches Assoc. Prof. Dr. Arzu ÇIĞ cultivation sustainibility ecology propagation ORNAMENTAL PLANTS IN DIFFERENT APPROACHES EDITOR Assoc. Prof. Dr. Arzu ÇIĞ AUTHORS Atilla DURSUN Feran AŞUR Husrev MENNAN Görkem ÖRÜK Kazım MAVİ İbrahim ÇELİK Murat Ertuğrul YAZGAN Muhemet Zeki KARİPÇİN Mustafa Ercan ÖZZAMBAK Funda ANKAYA Ramazan MAMMADOV Emrah ZEYBEKOĞLU Şevket ALP Halit KARAGÖZ Arzu ÇIĞ Jovana OSTOJIĆ Bihter Çolak ESETLILI Meltem Yağmur WALLACE Elif BOZDOGAN SERT Murat TURAN Elif AKPINAR KÜLEKÇİ Samim KAYIKÇI Firat PALA Zehra Tugba GUZEL Mirjana LJUBOJEVIĆ Fulya UZUNOĞLU Nazire MİKAİL Selin TEMİZEL Slavica VUKOVIĆ Meral DOĞAN Ali SALMAN İbrahim Halil HATİPOĞLU Dragana ŠUNJKA İsmail Hakkı ÜRÜN Fazilet PARLAKOVA KARAGÖZ Atakan PİRLİ Nihan BAŞ ZEYBEKOĞLU M. Anıl ÖRÜK Copyright © 2020 by iksad publishing house All rights reserved. No part of this publication may be reproduced, distributed or transmitted in any form or by any means, including photocopying, recording or other electronic or mechanical methods, without the prior written permission of the publisher, except in the case of brief quotations embodied in critical reviews and certain other noncommercial uses permitted by copyright law. Institution of Economic Development and Social Researches Publications® (The Licence Number of Publicator: 2014/31220) TURKEY TR: +90 342 606 06 75 USA: +1 631 685 0 853 E mail: [email protected] www.iksadyayinevi.com It is responsibility of the author to abide by the publishing ethics rules. Iksad Publications – 2020© ISBN: 978-625-7687-07-2 Cover Design: İbrahim KAYA December / 2020 Ankara / Turkey Size = 16 x 24 cm CONTENTS PREFACE Assoc. Prof. Dr. Arzu ÇIĞ……………………………………………1 CHAPTER 1 DOUBLE FLOWER TRAIT IN ORNAMENTAL PLANTS: FROM HISTORICAL PERSPECTIVE TO MOLECULAR MECHANISMS Prof. -
Traditional Uses, Phytochemistry and Pharmacology of Genus Fritillaria—A Review Ishrat Rashid1 and Ubaid Yaqoob2*
Rashid and Yaqoob Bull Natl Res Cent (2021) 45:124 https://doi.org/10.1186/s42269-021-00577-z Bulletin of the National Research Centre REVIEW Open Access Traditional uses, phytochemistry and pharmacology of genus Fritillaria—a review Ishrat Rashid1 and Ubaid Yaqoob2* Abstract Background: Genus Fritillaria is one among the biggest genera of family Liliaceae comprising of around 130–165 species. Fritillaria is viewed as a signifcant genus and a source of signifcant pharmaceutically active compounds utilized in conventional drugs by folklore. Fritillaria is utilized worldwide as medication and food. Diferent chemically dynamic components separated from genus Fritillaria, their phytochemistry with structure and pharmacology of these compounds have been extensively reviewed. Main body: Fritillaria is utilized for treatment of dyspepsia, chest injury, tuberculosis, cough, asthma, gout, bronchi- tis, dysuria, sinus, boils, stomatitis, malaria, insanity, anaemia, immunity promoter, remedy for child emaciation, fever, burning sensation, phthisis and broncho-asthma, heart diseases, dysfunction of breathing and nervous system, etc. Diferent chemical components isolated from genus Fritillaria include around 120 alkaloids, 15 terpenoids as well as saponins, glycosides, volatile components, nucleosides, amino acids, nucleobases, favonoids, fatty acids and so forth. Conclusions: Many Fritillaria species have been utilized in traditional Chinese medication on account of their efects of clearing heat, moistening the lung, alleviating cough, asthma, tumours, scrofula and so on. Fritillaria is utilized for treatment of dyspepsia, chest injury, tuberculosis, cough, asthma, gout, bronchitis, dysuria, sinus, boils, stomatitis, malaria, insanity, anaemia, immunity promoter, remedy for child emaciation, also for fever, burning sensation, phthisis and broncho-asthma, heart diseases, dysfunction of breathing and nervous system, etc. -
Downloaded from Genbank (F
Preprints (www.preprints.org) | NOT PEER-REVIEWED | Posted: 17 March 2017 doi:10.20944/preprints201703.0139.v1 Peer-reviewed version available at Molecules 2017, 22, , 982; doi:10.3390/molecules22060982 Article The Complete Chloroplast Genome Sequences of Fritillaria ussuriensis Maxim. and Fritillaria cirrhosa D. Don, and Comparative Analysis with Other Fritillaria Species Inkyu Park1, Wook-Jin Kim1, Sang-Min Yeo1, Goya Choi1, Young-Min Kang1, Renzhe Piao2 and Byeong-Cheol Moon1* 1 K-herb Research Center, Korea Institute of Oriental Medicine, Daejeon 305-811, Republic of Korea; [email protected] (I.K.P.); [email protected] (W.J.K); [email protected] (S.M.Y); [email protected] (G.C.); [email protected] (Y.M.K) 2 Department of Agronomy, Yanbian University Agriculture College, Yanji 133002, China ; [email protected] (R.P.) * Correspondence: [email protected]; Tel.: +82-42-868-9530 Abstract: The genus Fritillaria belongs to the widely distributed family Liliaceae. The bulbs of Fritillaria ussuriensis and Fritillaria cirrhosa are valuable herbaceous medicinal ingredients. However, they are still used indiscriminately in herbal medicine. Identification and molecular phylogenic analysis of Fritillaria species is therefore required. Here, we report the complete chloroplast (cp) genome sequences of F. ussuriensis and F. cirrhosa. The two Fritillaria cp genomes were 151,524 and 151,083 bp in length, respectively, including a pair of inverted repeat regions (52,678 and 52,156 bp) separated by a large single copy region (81,732 and 81,390 bp) and small single copy region (17,114 and 17,537 bp). -
The Pharmaceutical Research of Bulbus Fritillariae
e-ISSN:2321-6182 p-ISSN:2347-2332 Research and Reviews: Journal of Pharmacognosy and Phytochemistry The Pharmaceutical Research of Bulbus Fritillariae Qingdan Du, Dongdong Wang, Shu Wang Department of Pharmacognosy, West China College of Pharmacy, Sichuan University, No. 17, Duan 3, Renmin Nan Road, Chengdu 610041, Peoples’ Republic of China. Review Article Received date: 07/08/2015 ABSTRACT Accepted date: 30/12/2015 The Bulbus Fritillariae (BF) is a Traditional Chinese Medicine treating Published date: 07/01/2016 cough and asthma. This article summarized the present research on BFs and mainly focused on the alkaloids, which are the most effective *For Correspondence components in BFs. The article contained the geographical distribution, identification of BFs, and the extraction, isolation of the alkaloids, as well Shu Wang, Department of Pharmacognosy, West as the pharmacological efficacy and bioavailability of BFs. China College of Pharmacy, Sichuan University, No. 17, Duan 3, Renmin Nan Road, Chengdu 610041, PR China, Tel: +86 28 85503950 E-mail: [email protected] Keywords: Bulbus Fritllariae; Alkaloids; Identification; Extraction; Isolation; Pharmacological effect; Bioavailability INTRODUCTION The Bulbus Fritillariae (BF), known by the Chinese name “Bei-Mu”, belongs to the family Liliaceae. There are five Fritillaria species documented as “Bei-Mu”, which are Bulbus Fritillariae Cirrhosae, Bulbus Ussuriensis Fritillariae, Bulbus Pallidiflorae Fritillariae, Bulbus Thunbergil Fritillariae as well as Bulbus Hupehensis Fritillariae. Among these species, Bulbus Fritillariae Cirrhosae and Bulbus Fritillariae Thunbergia, which are called “Chuan-Bei-Mu” and “Zhe-Bei-Mu” in Chinese, are acknowledged as the two most effective species [1]. The former contains six species, including Fritillaria cirrhosa D.Don, Fritillaria unibracteata Hsiao et K.C.Hsia, Fritillaria przewalskii Maxim, Fritillaria delavayi Franch, Fritillaria taipaiensis P.Y.Li and Fritillaria unibracteata Hsiao et K.C.Hisa var.wabuenis [2,3]. -
The Complete Chloroplast Genome Sequences of Fritillaria Ussuriensis Maxim
Article The Complete Chloroplast Genome Sequences of Fritillaria ussuriensis Maxim. and Fritillaria cirrhosa D. Don, and Comparative Analysis with Other Fritillaria Species Inkyu Park 1, Wook Jin Kim 1, Sang-Min Yeo 1, Goya Choi 1, Young-Min Kang 1, Renzhe Piao 2 and Byeong Cheol Moon 1,* 1 K-Herb Research Center, Korea Institute of Oriental Medicine, Daejeon 305-811, Korea; [email protected] (I.P.); [email protected] (W.J.K.); [email protected] (S.-M.Y.); [email protected] (G.C.); [email protected] (Y.-M.K.) 2 Department of Agronomy, Yanbian University Agriculture College, Yanji 133002, China; [email protected] * Correspondence: [email protected]; Tel.: +82-42-868-9530 Academic Editor: Derek J. McPhee Received: 6 March 2017; Accepted: 10 June 2017; Published: 13 June 2017 Abstract: The genus Fritillaria belongs to the widely distributed Liliaceae. The bulbs of Fritillaria (F. ussuriensis and F. cirrhosa are valuable herbaceous medicinal ingredients. However, they are still used indiscriminately in herbal medicine. Identification and molecular phylogenic analysis of Fritillaria species are therefore required. Here, we report the complete chloroplast (CP) genome sequences of F. ussuriensis and F. cirrhosa. The two Fritillaria CP genomes were 151,524 and 151,083 bp in length, respectively, and each included a pair of inverted repeated regions (52,678 and 52,156 bp) that was separated by a large single copy region (81,732 and 81,390 bp), and a small single copy region (17,114 and 17,537 bp). A total of 111 genes in F. -
Cytotaxonomical Analysis of Eleven Turkish Fritillaria L
IUFS Journal of Biology Research Article IUFS J Biol 2016, 75(2): 19-28 Cytotaxonomical analysis of eleven Turkish Fritillaria L. (Liliaceae) taxa Mine Koçyiğit1*, Ufuk Rastgeldi2, Erdal Kaya3 1Istanbul University, Faculty of Pharmacy, Department of Pharmaceutical Botany, Beyazit, Istanbul/Turkey. 2 GAP Agricultural Research Institute, Sanlıurfa/Turkey 3 Central Horticultural Research Institute, Yalova/Turkey Abstract This paper reports the chromosome numbers of eleven Turkish Fritillaria taxa from seventeen populations along with their karyotypes and ideograms. They are F. hermanis subsp. amana (Rix) R.Wallis & R.B.Wallis 2n=24, F. armena Boiss. 2n=24 (endemic), F. aurea Schott 2n=24 (endemic), F. crassifolia Boiss. & A.Huet subsp. crassifolia 2n=24 (endemic), F. crassifolia Boiss. & A.Huet subsp. kurdica (Boiss. & Noë) Rix 2n=24 (endemic), F. imperialis L. 2n=26+2B, 24+3B, 24, 26+3B, F. minuta Boiss. & Noë 2n=24, F. persica L. 2n=24, F. pinardii Boiss. 2n=24, 24+5B, F. uva-vulpis Rix 2n=36 and F. viridiflora Post 2n=24 (endemic). The Fritillaria uva-vulpis was the only triploid, others were diploid with some B chromosomes. The basic chromosome numbers were counted as x= 12 or 13. For all karyological characters of taxa, the correlation coefficient was defined and grouping was performed by cluster analysis (UPGMA, similarity) and by ordination based on principal-components analysis (PCA). Keywords: Fritillaria, chromosome number, UPGMA, PCA, Turkey. *Corresponding author: Mine Koçyiğit (e-mail: [email protected]) (Received: 13.03.2017 Accepted: 28.03.2017) Türkiye’deki 11 Fritillaria L. (Liliaceae) türünün Sitotaksonomik Analizi Özet Türkiye’deki 17 populasyondan 11 Fritillaria taksonunun karyotipleri ve idiyogramları verilmektedir. -
BASKİL TERS LALESİ (Fritillaria Baskilensis Behcet)'NİN DOKU KÜLTÜRÜYLE ÇOĞALTILMASI Tuba SARİ Moleküler Biyoloji V
BASKİL TERS LALESİ (Fritillaria baskilensis Behcet)’NİN DOKU KÜLTÜRÜYLE ÇOĞALTILMASI Tuba SARİ Yüksek Lisans Tezi Moleküler Biyoloji ve Genetik Anabilim Dalı Danışman: Prof. Dr. Ömer MUNZUROĞLU AĞUSTOS-2016 ÖZET Yüksek Lisans BASKİL TERS LALESİ (Fritillaria baskilensis Behcet)’NİN DOKU KÜLTÜRÜYLE ÇOĞALTILMASI Tuba SARİ Fırat Üniversitesi Fen Bilimleri Enstitüsü Moleküler Biyoloji Anabilim Dalı Danışman: Prof. Dr. Ömer MUNZUROĞLU 2016 Bu çalışmada ülkemiz için endemik olan ve türü tehlike altında olduğu bildirilen Baskil Ters Lalesi (Fritillaria baskilensis Behçet)’nin in vitro çoğaltımı amaçlandı. Eksplantlar bitkinin soğan, açmamış çiçek tepalleri ve çiçek saplarından elde edildi. Deneylerde MS (vitaminli) temel besi ortamı, %3 ve %6 sükroz ile NAA, IAA ve BA gibi bitki büyüme düzenleyicileri (PGR) kullanıldı. Yüzey sterilizasyonu işlemleri etil alkol ve sodyum hipoklorit (NaOCl) kullanılarak yapıldı. Eksplantlar 20±1 oC’de gelişmeye bırakıldı. 8 saat karanlık ve 16 saat ışık fotoperiyot uygulandı. İlk 30 günlük inkübasyon sonunda, canlı kalan (%85,94) soğan eksplantlarının %38.4’ünde kallus oluşumu, % 8.6 ‘sında soğancık oluşumu görüldü.120 günlük inkübasyon süresinin sonunda en iyi sonuç %3 sükroz içeren yüksek sitokininli ortam (1 BA + 0.6 NAA + 0.4 IAA)’da alındı. Bu ortamda soğan eksplantlarının % 96.42’sinde direkt veya endirekt organogenez, geriye kalan % 3.57’sinde sadece kallus oluşumu görüldü. PGR içermeyen temel besi ortamında sükroz bulunmadığı zaman %48.13 oranında kallus oluşumu görülmesine rağmen organogenez gerçekleşmedi. %3 sükroz oranı % 6 sükroza göre kallus + sürgün oluşumunda %147.2, kallus + soğancık oluşumunda %153.3 oranlarında daha fazla etkili oldu. %3 sükroz ve yüksek sitokinin (1 mg/L BA + 0.6 mg/L NAA + 0.4 mg/L IAA) birlikte bulunduğu zaman toplam III organogenez arttı. -
Phylogenetic Analysis of Fritillaria Cirrhosa D. Don and Its Closely Related Species Based on Complete Chloroplast Genomes
Phylogenetic analysis of Fritillaria cirrhosa D. Don and its closely related species based on complete chloroplast genomes Qi Chen1, Xiaobo Wu1 and Dequan Zhang1,2 1 College of Pharmacy and Chemistry, Dali University, Dali, Yunnan, China 2 Institute of Materia Medica, Dali University, Dali, Yunnan, China ABSTRACT Fritillaria cirrhosa D. Don, whose bulb is used in a well-known traditional Chinese medicine to relieve cough and eliminate phlegm, is one of the most important medicinal plants of Fritillaria L. The species is widely distributed among the alpine regions in southwestern China and possesses complex morphological variations in different distributions. A series of newly related species were reported, based on obscure morphological differences. As a result, F. cirrhosa and its closely related species constitute a taxonomically complex group. However, it is difficult to accurately identify these species and reveal their phylogenetic relationships using traditional taxonomy. Molecular markers and gene fragments have been adopted but they are not able to afford sufficient phylogenetic resolution in the genus. Here, we report the complete chloroplast genome sequences of F. cirrhosa and its closely related species using next generation sequencing (NGS) technology. Eight plastid genomes ranged from 151,058 bp to 152,064 bp in length and consisted of 115 genes. Gene content, gene order, GC content, and IR/SC boundary structures were highly similar among these genomes. SSRs and five large repeat sequences were identified and the total number of them ranged from 73 to 79 and 63 to 75, respectively. Six highly divergent regions were successfully identified that could be used as potential genetic markers of Fritillaria. -
Phytochemical and Biological Research of Fritillaria Medicinal Resources
Chinese Journal of Natural Chinese Journal of Natural Medicines 2013, 11(4): 03300344 Medicines doi: 10.3724/SP.J.1009.2013.00330 Phytochemical and biological research of Fritillaria medicinal resources HAO Da-Cheng1*, GU Xiao-Jie 1, XIAO Pei-Gen2*, PENG Yong2 1Biotechnology Institute, School of Environment, Dalian Jiaotong University, Dalian 116028, China; 2Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine of Ministry of Education, Insti- tute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Beijing 100193, China Available online 20 July 2013 [ABSTRACT] The genus Fritillaria is a botanical source for various pharmaceutically active components, which have been commonly used in traditional Chinese medicine for thousands of years. Increasing interest in Fritillaria medicinal resources has led to additional discoveries of steroidal alkaloids, saponins, terpenoids, glycosides and many other compounds in various Fritillaria species, and to investigations on their chemotaxonomy, molecular phylogeny and pharmacology. In continuation of studies on Fritillaria pharmaco- phylogeny, the phytochemistry, chemotaxonomy, molecular biology and phylogeny of Fritillaria and their relevance to drug efficacy is reviewed. Literature searching is used to characterize the global scientific effort in the flexible technologies being applied. The interre- lationship within Chinese Bei Mu species and between Chinese species, and species distributed outside of China, is clarified by the molecular phylogenetic inferences based on nuclear and chloroplast DNA sequences. The incongruence between chemotaxonomy and molecular phylogeny is revealed and discussed. It is essential to study more species for both the sustainable utilization of Fritillaria medicinal resources and for finding novel compounds with potential clinical utility. Systems biology and omics technologies will play an increasingly important role in future pharmaceutical research involving the bioactive compounds of Fritillaria. -
Plant Super-Barcode: a Case Study on Genome-Based Identification For
Wu et al. Chin Med (2021) 16:52 https://doi.org/10.1186/s13020-021-00460-z Chinese Medicine RESEARCH Open Access Plant super-barcode: a case study on genome-based identifcation for closely related species of Fritillaria Lan Wu1†, Mingli Wu1†, Ning Cui1, Li Xiang1, Ying Li2, Xiwen Li1* and Shilin Chen1* Abstract Background: Although molecular analysis ofers a wide range of options for species identifcation, a universal meth- odology for classifying and distinguishing closely related species remains elusive. This study validated the efective- ness of utilizing the entire chloroplast (cp) genome as a super-barcode to help identify and classify closely related species. Methods: We here compared 26 complete cp genomes of ten Fritillaria species including 18 new sequences sequenced in this study. Each species had repeats and the cp genomes were used as a whole DNA barcode to test whether they can distinguish Fritillaria species. Results: The cp genomes of Fritillaria medicinal plants were conserved in genome structure, gene type, and gene content. Comparison analysis of the Fritillaria cp genomes revealed that the intergenic spacer regions were highly divergent compared with other regions. By constructing the phylogenetic tree by the maximum likelihood and maximum parsimony methods, we found that the entire cp genome showed a high discrimination power for Fritillaria species with individuals of each species in a monophyletic clade. These results indicate that cp genome can be used to efectively diferentiate medicinal plants from the genus Fritillaria at the species level. Conclusions: This study implies that cp genome can provide distinguishing diferences to help identify closely related Fritillaria species, and has the potential to be served as a universal super-barcode for plant identifcation.