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Dental Medicine PITT Summer 2017 DENTAL MEDICINE Research That Inspires and Heals: Pitt emerges as a national leader in translational research IN THIS ISSUE FROM THE DEAN Research is one of the three legs of the academic stool of the University. The others, of course, are service in the form of patient care at our school, and teaching. Research actually serves as the Bridging the Research Gap: 17th Annual Dean’s Saluting the Class of 2017: basis for the other two legs as well. Acquisition How Pitt Dental Medicine is Scholarship Ball: Members of the Class of at the forefront of bringing Honoring students 2017 and their families of new knowledge to enhance the human 4 new developments into 28 and alumni in style at 44 enjoyed a celebratory condition is the fundamental underlying principle clinical therapies. Phipps Conservatory. luncheon in May to honor that drives health care research. The School of National Institute of Dental and Craniofacial their graduation. Dental Medicine is extremely fortunate to have Research (NIDCR). Moreover, we have significant such a strong research base. The Commission on funding from entities other than the NIDCR. A Messages from Community Dental Accreditation (CODA) recently site visited perfect example of translating our research is the 20 the Alumni President 36 Outreach and Vice President the school and noted our Center for Craniofacial recent acquisition of a U24 grant by Dr. Charles and Dental Genetics, and Center for Craniofacial Sfeir in the Center for Craniofacial Regeneration Regeneration, as exemplars among dental to facilitate the translation of bench research Summer 2017 Volume 16, Number 1 Alumni Where Are They Now: schools for the research done here. These two through the FDA approval process and on to 21 Updates 38 John J. Yurosko, DMD Dean Thomas W. Braun Pitt Centers of Excellence are perfect examples clinicians, such as yourselves, for direct patient Editor James Rosendale of direct clinical applicability to patients. care. This collaborative grant with the University Dental Alumni Association The Center for Craniofacial Regeneration is of Michigan and Harvard University is one of only Pitt Dental Diploma President Lisa Babb composed of scientists who are developing two awarded nationally. 22 Weekend 40 Ceremony Vice President, Dental Affairs Cheryl Rosato materials and methods to enhance the tissue Vice President, Dental Hygiene Susan Ban of the dental and craniofacial skeletons. Our These extensive activities also permit our Go Speed Racer: Faculty Secretary Arnold Peace scientists in the Center for Craniofacial and students, residents and other faculty members 34 Dr. Arnold Peace Lives 47 Updates Alumni Affairs Director Nancy Poe Dental Genetics are actively working to identify to be actively involved in the research endeavor. Life in the Fast Lane Contributing Staff Alycia Maltony various genetic factors involved in facial form I hope you will enjoy and appreciate the articles University of Pittsburgh and function, and in particular, those associated which follow in this month’s Pitt Dental School of Dental Medicine Office of Alumni Affairs and Development with facial clefting. These two key areas Medicine magazine. 440 Salk Hall, 3501 Terrace Street represent significant aspects of patient care. We Pittsburgh PA 15261 in dental medicine are pivotal in the application Sincerely, ON THE COVER Summer 2017 dental.pitt.edu PITT of the principles that are derived from this Together with Teaching and Service, DENTAL Pitt Dental Medicine is published MEDICINE semiannually by the Office of the Dean as research. Being centrally located in the University Research is one of the three legs of the a service to alumni, students, and friends. mission of the School of Dental Medicine. Its purpose is to facilitate communication of Pittsburgh campus, we have extensive among alumni, students, and friends of the Thomas W. Braun (DMD ’73, PhD ’77) Pictured here are some of the research School of Dental Medicine. This publication opportunities to collaborate with partners in Distinguished Service Professor and Dean, leaders who are helping to develop holds itself not responsible for opinions, research, including engineering, medicine and theories, and criticisms therein contained. University of Pittsburgh therapies for patients in dental offices Research That computer science. Our school continues to be world-wide. Inspires and Heals: University of Pittsburgh is an affirmative School of Dental Medicine Pitt emerges as a national leader recognized in the top 10 as funded by the in translational research action, equal opportunity employer. Pictured left to right: Dr. Charles Sfeir, Dr. Elia Beniash, Dr. Robert Weyant, Dr. Mark Mooney, and Dr. Mary Marazita. 2 PITT DENTAL MEDICINE dental.pitt.edu 3 Creating the Future of Therapies Through Research The Center for Craniofacial mineralized tissue biology; tissues, with the Department Regeneration (CCR) is a of Endodontics on pulp • the development of surgical University of Pittsburgh regeneration, and with the fixation devices using Bridging the designated Center of Excellence Department of Periodontics to resorbable metals; directed by Charles Sfeir, DDS, develop treatments for patients PhD, who also is the Associate • the development of novel with periodontal disease. Dean of Research, and chair of periodontal therapies using The CCR also reaches beyond the Department of Periodontics modulation strategies to be the field of dentistry and works and Preventive Medicine at the utilized in dental offices; interprofessionally with many School of Dental Medicine. • the development of tissue schools, departments, and areas Both a clinician and researcher, of study at the University, such ResearchPitt Dental Medicine is at the forefront engineering strategies for Gap Dr. Sfeir seeks new treatments for pulp tissue regeneration, as the Schools of Pharmacy of bringing new developments into clinical therapies. patients by undertaking some of improving endodontic and Engineering. Many clinical the region’s most cutting edge treatments; and and research faculty members research. Research studies in the at the school also are members • translational research CCR range from the molecular of the University of Pittsburgh’s that involves pre-clinical and cellular to the whole- McGowan Institute for models. The School of Dental Medicine has been one of the nation’s leading research institutions for most of its organism level. Research in the Regenerative Medicine, one of long history. Throughout the past decade, the school has been a top-tier ranked National Institutes of CCR focuses on the development the premiere research centers Much of the research Health (NIH)/National Institute of Dental and Craniofacial Research (NIDCR) institution. Funding from these of new therapies, biomaterials, in the nation bringing together undertaken in the Center is of organizations and others, such as the Department of Defense and private corporations, has supported and diagnostic tools for the varied disciplines from an intraprofessional nature and many types of research at the school. Such successful research efforts also can be traced to the cooperative treatment of craniofacial throughout the University. involves other departments approach taken together by research and clinical faculty. diseases and disorders in the at the school. For instance, following areas: New, influential and exciting research is taking place in the Center for Craniofacial Regeneration (CCR) and researchers in the CCR work Pictured above from left to right: , the Center for Craniofacial and Dental Genetics (CCDG), which means better treatments for clinicians and • the development of bio-inspired Dr. Juan Taboas side-by-side with clinical faculty Ms. Tyler Swenson, patients, and for the future of dental medicine. materials for mineralized members from the Department Dr. Kostantinos Verdelis, tissue engineering as well as of Oral and Maxillofacial Surgery Ms. Victoria Smethurst, Researchers at the school moved into the newly opened Salk Research Pavilion in September, 2015, to Ms. Tyler Swenson, understanding extracellular to seek surgical treatments for continue their research efforts in better equipped space. Mr. Yong Wan, matrix proteins involved in regenerating bone and other Dr. Heather Szabo-Rogers, Ms. Brandi Lantz, and Mr. Adam Chin. 4 PITT DENTAL MEDICINE dental.pitt.edu 5 COVER STORY Building a Network to Move Tissue Regeneration Therapies into Clinics, Quickly The majority of products we use in dental clinics require FDA approval. The journey of moving these products from the research bench into clinical therapy can be lengthy and arduous. The National Institute of Health (NIH) funds much of the basic science research that will become therapies for our patients. In order to accelerate the transition of the research from the research bench to a therapy, the University of Pittsburgh School of Dental Medicine Department of Periodontics received an $11.7 million grant from the National Institute of Dental and Craniofacial Research (NIDCR) to establish a resource center dedicated to advancing therapies for regenerating damaged dental, oral and craniofacial tissues. Pictured above, left to right: Dr. Sayuri Smith, Pictured above, left to right: Mr. Xu Yang, Ms. Abigail Jarrett, The Michigan-Pittsburgh-Wyss Resource Center: Regenerative Medicine provide outstanding Mr. Mostasfa Shebaheldin, Mr. Chu Chih Hung, Mr. Ballav Borah, and Dr. Eliah Beniash. Ms. Dandan Hong, and Dr. Charles Sfeir. Supporting Regenerative Medicine
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