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Home , Dirofilaria immitis

PRICE LIST 2018 1

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Table of Contents

• Abbreviations used ……………………………………….…..………………….…… 3

• Infectious disease PCRs/ …………………………………………………..… 3

• Infectious disease PCRs/ ………………………..……………………………. 5

• Infectious disease PCRs/Horses …………………….…………………………..… 6

• Infectious disease PCRs/Pigs and Cattle ..…………………..…….………….. 7

• Infectious disease PCRs/Birds and Rabbits ……………….……….………….. 7

• Infectious disease PCR profiles …………………………………….…………....… 7

• Genetic diseases ………………………………………………………….………..…... 9 2

• Genetic disease profiles/Dogs and Cats ……………..…………....….....….. 14

• Veterinary molecular oncology/diseases …………...……………….…...… 16

• Immunofluorescence Serology/diseases …………….………………..….… 17

• Immunofluorescence Serology/disease profiles …….……………...... 18

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Abbreviations used

AH = aqueous humour FS = faecal swab @B/C = biopsy/cytology JF= joint fluid BAL = bronchoalveolar/tracheal lavage NS = nasal swab BM = bone marrow OSP = oropharyngeal swab BS = buccal swab PL = plasma CS = cloacal swab S = swab CSF = cerebrospinal fluid SE = serum CSW = conjunctival swab SP = sperm EB = EDTA blood T = tissue EBS = EDTA blood swab F/VS = foreskin/vaginal swab F = feathers U = urine FC = feces

INFECTIOUS DISEASE PCRS/Dogs 3

M a x i m u m P r i c e i n T e s t Abbreviations Analysis turnaround e u r o s VAT t i m e i n c l . 85 Acanthamoeba spp B/C Real-time PCR 1 - 2 g g 5 3 , 6 8 24 Anaplasma phagocytophilum EB, B / C , CSF Real-time PCR 1 - 2 g g 5 3 , 6 8 70 Anaplasma platys EB, B / C , CSF PCR 1 - 2 g g 5 3 , 6 8 86 Angiostrongilus vasorum EB Real-time PCR 1 - 2 g g 5 3 , 6 8 1 3 6 Antibiotic resistance ( MRSA ) EB PCR 1 - 2 g g 3 6 , 6 0 3 Babesia canis B / C , EB Real-time PCR 1 - 2 g g 5 3 , 6 8 2 5 0 Babesia gibsoni B / C , EB Real-time PCR 1 - 2 g g 5 3 , 6 8 36 Bordetella bronchiseptica NS, BAL Real-time PCR 1 - 2 g g 4 6 , 9 7 25 Real-time TaqMan® Borrelia burgdorferii EB, CSF , JF 1 - 2 g g 4 6 , 9 7 PCR 37 C A V 2 ( c a n i n e adenovirus t y p e 2 ) NS, OSP , BAL , F C Real-time PCR 1 - 2 g g 4 6 , 9 7 32 C C O V ( c a n i n e coronavirus) FC RT Real-time PCR 1 - 2 g g 5 3 , 6 8 1 3 5 Carbapenem antibiotic resistance EB PCR 1 - 2 g g 6 1 , 0 0 1 3 7 Cestoda spp FC PCR 1 - 2 g g 4 6 , 9 7 6 0 7 Clostridium botulinum contact lab PCR 1 - 2 g g 8 0 , 5 2 35 Cryptosporidium spp. FC Real-time PCR 1 - 2 g g 5 3 , 6 8 1 0 0 C y t a u x z o o n FC PCR 1 - 2 g g 4 6 , 9 7 26 i m m i t i s EB, B / C Real-time PCR 1 - 2 g g 4 0 . 2 6 27 EB, B / C Real-time PCR 1 - 2 g g 4 0 . 2 6 6 D i s t e m p e r CSF, EB, OSP RT Real-time PCR 1 - 2 g g 5 1 , 2 4 9 Ehrlichia (Anaplasma) spp. EB, B / C , CSF Real-time PCR 1 - 2 g g 5 3 , 6 8 10 Ehrlichia canis EB, B / C , CSF Real-time PCR 1 - 2 g g 5 3 , 6 8

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80 Encephalitozoon cunicoli U , B / C , T Real-time PCR 1 - 2 g g 5 3 , 6 8

34 Genotyping Giardia assemblies FC Sequence analysis 1 5 g g 9 3 , 9 4 33 Real-time TaqMan® Giardia spp. FC 1 - 2 g g 5 3 , 6 8 PCR 49 B / C a n d g a s t r i c Helicobacter spp. Real-time PCR 1 - 2 g g 5 3 , 6 8 BAL 84 H e p a t o z o o n EB, BM Real-time PCR 1 - 2 g g 4 2 . 7 0 22 Real-time TaqMan® Herpesvirus B / C , F/VS 1 - 2 g g 4 6 , 9 7 PCR 87 Histoplasma capsulatum Contact lab PCR 1 - 2 g g 6 1 , 0 0 1 Quantitative PCR Leishmania spp. B / C , BM, EB Real-time TaqMan®- 1 - 2 g g 4 6 , 9 7 MGB® PCR

4 Quantitative real- Leptospirosi s U , B / C , EB 1 - 2 g g 4 2 . 7 0 time TaqMan® PCR

71 M haematoparvum ( c a n i n e Real-time TaqMan®- EB 1 - 2 g g 5 3 , 6 8 haemobartonellosi s ) MGB® PCR 31 M h a emocanis (canine Real-time TaqMan®- EB 1 - 2 g g 5 3 , 6 8 haemobartonellosi s ) MGB® PCR 96 M y c o b a c t e r i um s p p EB PCR 1 - 2 g g 1 2 2 , 0 0 79 Mycoplasma canis F / V S , C S W Real-time PCR 1 - 2 g g 5 3 , 6 8 77 F/VS , J F , OSP , Mycoplasma spp Real-time PCR 1 - 2 g g 5 3 , 6 8 NS, CSW 39 Real-time TaqMan® Neospora caninum T , CSF 1 - 2 g g 4 8 . 8 0 PCR 38 RT Real-time nested Parainfluenza NS, OSP , BAL 1 - 2 g g 5 3 , 6 8 PCR 20 Quantitative real- Parvovirus EB, F C 1 - 2 g g 4 6 , 9 7 4 time PCR 97 Prototheca zopfii a n d wickerhamii EB, F C Real-time PCR 1 - 2 g g 4 6 , 9 7 17 Real-time TaqMan® Rickettsia spp. EB, B / C , CSF 1 - 2 g g 4 6 , 9 7 PCR 72 S c r e e n i n g - haemobartonellosi s ( M EB Real-time PCR 1 - 2 g g 8 0 , 5 2 haemocanis, M haematoparvum) 1 3 8 T e n i a c y c l o p h yll i d e a n EB PCR 1 - 2 g g 4 6 , 9 7 1 3 9 Tenia Hymenolepis EB PCR 1 - 2 g g 4 6 , 9 7 98 T e n i a s p p FC PCR 1 - 2 gg 4 6 , 9 7 40 T y p i n g - Parvovirus EB, F C Sequence analysis 1 5 g g 9 3 , 9 4 99 T y p i n g - f u n g h i EB, F C PCR 1 5 g g 1 2 2 , 0 0 7 Real-time TaqMan® Toxoplasma gondii FC, CSF , B / C , AH 1 - 2 g g 4 6 , 9 7 PCR 73 Real-time TaqMan® spp. EB, B / C 1 - 2 g g 4 0 . 2 6 PCR

INFECTIOUS DISEASE PCRS/Cats

M a x i m u m P r i c e i n A b b r e v i a t i T e s t Analysis turnaround e u r o s V A T o n s t i m e i n c l . 28 Bartonella spp. – ( scratch desease) EB Real-time PCR 1 - 2 g g 4 6 , 9 7 12 RT Real-time nested Calicivirus OSP 1 - 2 g g 5 3 , 6 8 PCR 75 C a n d . M haemominutum Quantitative real- EB time TaqMan®- 1 - 2 g g 5 3 , 6 8 ( haemobartonellosi s ) MGB PCR

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76 Quantitative real- Cand. M turicensis EB time TaqMan®- 1 - 2 g g 5 3 , 6 8 ( haemobartonellosi s ) MGB PCR 8 Chlamidophyla felis CSW , B / C Real-time PCR 1 - 2 g g 4 6 , 9 7 6 0 7 Clostridium botulinum contact lab PCR 1 - 2 g g 8 0 , 5 2 15 Coronavirus Felino (ricerca mRNA rif. EB RT real-time PCR 1 - 2 g g 5 3 , 6 8 Simons et al., 2005) 35 Cryptosporidium spp. FC Real-time PCR 1 - 2 g g 5 3 , 6 8 80 Encephalitozoon cunicoli U , B / C , T Real-time PCR 1 - 2 g g 5 3 , 6 8

16 RT Real-time nested FCOV (Feline Corona Virus) FC, e f f u s i o n 1 - 2 g g 5 3 , 6 8 PCR

13 Real-time TaqMan® FELV () B / C , BM, EB 1 - 2 g g 4 6 , 9 7 PCR 14 FIV (Feline Immunodeficiency Virus) B / C , BM, EB Real-time PCR 1 - 2 g g 4 6 , 9 7

34 G i a r d i a assemblages/genotyping FC Sequence analysis 1 5 g g 9 3 , 9 4 33 Real-time TaqMan® Giardia spp. FC 1 - 2 g g 5 3 , 6 8 PCR 23 Herpesvirus F/VS , EB Real-time PCR 1 - 2 g g 4 6 , 9 7

74 M haemofelis Quantitative real- EB time TaqMan®- 1 - 2 g g 5 3 , 6 8 ( haemobartonellosi s ) MGB PCR 21 Quantitative real- Parvovirus (panleucopenia) EB, F C 1 - 2 g g 4 6 , 9 7 time PCR 11 S c r e e n i n g - haemobartonellosi s ( M haemofelis, M haemominutum; M B / C , BM, EB Real-time PCR 1 - 2 g g 5 3 , 6 8 turicensis) 7 FC, CSF , Real-time TaqMan® Toxoplasma gondii 1 - 2 g g 4 6 , 9 7 B / C , AH PCR 5 81 Real-time nested Tritrichomonas foetus FC,FS 1 - 2 g g 5 3 , 6 8 PCR

INFECTIOUS DISEASE PCRS/Horses

M a x i m u m P r i c e i n Abbreviatio T e s t Analysis turnaround e u r o s V A T ns t i m e i n c l . 56 Adenovirus t y p e 1 B / C , S PCR 1 - 2 g g 5 3 , 6 8 57 Adenovirus t y p e 2 B / C , S PCR 1 - 2 g g 5 3 , 6 8 24 Anaplasma phagocytophilum EB, B / C , CSF Real-time PCR 1 - 2 g g 5 3 , 6 8 58 EB, F/VS , S P , Arterivirus ( infectious a r t e r i t e ) RT PCR 1 - 2 g g 5 3 , 6 8 B / C , T 29 Babesia caballi EB Real-time PCR 1 - 2 g g 4 8 . 8 0 61 Clostridium piliforme FC PCR 1 - 2 g g 5 3 , 6 8 64 Coronavirus FC Real-time PCR 1 - 2 g g 5 3 , 6 8 35 Cryptosporidium spp. FC Real-time PCR 1 - 2 g g 5 3 , 6 8 9 Ehrlichia (Anaplasma) spp. EB, B / C , CSF Real-time PCR 1 - 2 g g 5 3 , 6 8 47 EB, S , CSF , Real-time E H V 1 (Equine Herpes Virus 1) 1 - 2 g g 5 3 , 6 8 B / C , T TaqMan® PCR 54 EB, S , BAL , E H V 2 (Equine Herpes Virus 2) Real-time PCR 1 - 2 g g 5 3 , 6 8 B/C, T 53 E H V 3 (Equine Herpes Virus 3) EB, S , B / C , T Real-time PCR 1 - 2 g g 5 3 , 6 8 48 Real-time E H V 4 (Equine Herpes Virus 4) EB, S , B / C , T 1 - 2 g g 5 3 , 6 8 TaqMan® PCR

55 E H V 5 (Equine Herpes Virus 5) EB, S , B / C , T Real-time PCR 1 - 2 g g 5 3 , 6 8

34 Giardia assemblages/genotyping FC Sequence analysis 1 5 g g 9 3 , 9 4

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33 Real-time Giardia spp. FC 1 - 2 g g 5 3 , 6 8 TaqMan® PCR 60 H a b r o n e m a microstoma FC PCR 1 - 2 g g 5 3 , 6 8 59 Habronema muscae FC PCR 1 - 2 g g 5 3 , 6 8 49 B/C e gastric Helicobacter spp. Real-time PCR 1 - 2 g g 5 3 , 6 8 l a v a g e 51 Influenza A virus EB RT PCR 1 - 2 g g 5 3 , 6 8 4 Quantitative real- Leptospirosis U , B / C , E B 1 - 2 g g 4 2 , 7 0 time TaqMan® PCR

62 Rhodococcus equi FC, S, B/C, PCR 1 - 2 g g 5 3 , 6 8 (rodococcosi) BAL 65 R o t a v i r u s FC RT PCR 1 - 2 g g 5 3 , 6 8 52 Streptococcus equi subsp. B / C , F/VS PCR 1 - 2 g g 6 1 , 0 0 zooepidemicus and subsp. equi

63 Taylorella equigenitalis F/VS PCR 1 - 2 g g 5 3 , 6 8 30 Theileria equi EB Real-time PCR 1 - 2 g g 4 8 . 8 0

INFECTIOUS DISEASE PCRS/Pigs and Cattle

M a x i m u m P r i c e i n T e s t Abbreviations Analysis turnaround e u r o s V A T t i m e i n c l . 2 4 9 Bovine Papillomavirus E B , S , T PCR 1 - 2 g g 4 6 , 9 7 44 Porcine Circovirus B / C , E B PCR 1 - 2 g g 4 6 , 9 7 5 PRRSV (Porcine Reproductive B/C, EB, SP RT Real-time PCR 1 - 2 g g 5 3 , 6 8 6 Respiratory Syndrome)

INFECTIOUS DISEASE PCRS/Birds and Rabbits

M a x i m u m P r i c e i n T e s t Abbreviations Analysis turnaround e u r o s V A T t i m e i n c l . 46 C h l a m i d i a p s i t t a c i EB, F C , CS Real-time PCR 1 - 2 g g 4 6 , 9 7 69 Circovirus PBFD (Psittacine Beak and EB, F C , CS, T Real-time PCR 1 - 2 g g 5 3 , 6 8 Feather Disease) 80 Encephalitozoon cunicoli U R , B / C , T Real-time PCR 1 - 2 g g 5 3 , 6 8 67 Psittacid Herpes v irus (Pacheco) EB, F C , CS, T PCR 1 - 2 g g 5 3 , 6 8

68 A v i a n Polyomaviru s EB, F C , CS, T Real-time PCR 1 - 2 g g 5 3 , 6 8 91 RHDV Calicivirus / R a b b i t s EB, contact lab PCR 1 - 2 g g 4 6 , 9 7

INFECTIOUS DISEASE PCR PROFILES

M a x i m u m P r i c e i n T e s t Abbreviations Analysis turnaround e u r o s V A T t i m e i n c l . 2 0 0 PCR Profile 1A/dogs - “ A r t h r o p o d - B / C , BM, EB Real-time TaqMan® 1 - 2 g g 9 1 , 5 0 b o r n e d i s e a s e s 1 ” PCR, Real-time PCR (Leishmania/Ehrlichia spp./Rickettsia spp.)

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2 4 6 PCR Profile 1B/ dogs B / C , BM, EB Real-time TaqMan® 1 - 2 g g 9 1 , 5 0 “ A r t h r o p o d - borne diseases 2 ” PCR, Real-time PCR (Leishmania/Ehrlichia canis/Rickettsia spp.) 2 0 2 PCR P r o f i l e 3/d o g s “ N e u r o l o g y ” Real-time TaqMan® 1 - 2 g g 1 1 5 , 9 0 (Distemper/Toxoplasma/ Neospora CSF , EB PCR, RT Real-time caninum) nested PCR 2 0 4 PCR Profile4/dogs - “ T i c k - b o r n e EB, B/C, CSF Real-time TaqMan® 1 - 2 g g 9 1 , 5 0 d i s e a s e s ” PCR, Real-time PCR (Babesia spp./Ehrlichia canis /Rickettsia spp.) 2 0 3 PCR Profile 5/dogs – “ E x p a n d e d EB, B/C, CSF Real-time TaqMan® 1 - 2 g g 1 0 3 , 7 0 t i c k - borne diseases” PCR, Real-time PCR ( Babesia spp./Ehrlichia canis /Rickettsia spp./Borrelia burgdorferii)

PCR Profile 6A/dogs - “Filariosis” 2 0 5 E B , B / C Real-time PCR 1 - 2 g g 4 8 , 8 0 (Dirofilaria immitis, Dirofilaria repens) 2 4 8 PCR Profile 6B/dogs Real-time TaqMan® “Filariosis new panel” EB PCR, Real-time PCR 1 - 2 g g 6 1 , 0 0 (Dirofilaria immitis, Wolbachia) 2 0 7 PCR Profile 7/dogs - “Intestinal Real-time TaqMan® p r o t o z o o ” FC PCR, Real-time PCR 1 - 2 g g 8 5 , 4 0 (Cryptosporidium, Giardia) 2 0 8 Real-time TaqMan® PCR Profile 8/dogs - “Intestinal” FC PCR, RT Real-time 1 - 2 g g 1 0 9 , 8 0 (CCOV, Parvovirus, Giardia) PCR PCR Profile 9/dogs - “ E x p a n d e d 2 0 9 Real-time PCR, RT intestinal” FC Real-time PCR, Real- 1 - 2 g g 1 2 2 , 0 0 (CCOV, Parvovirus, Giardia, time TaqMan® PCR Cryptosporidium) PCR Profile 10/dogs - 2 1 0 RT Real-time nested “Respiratory” EB, BAL, NS,OSP, PCR, Real-time PCR, 1 - 2 g g 1 2 2 , 0 0 (Distemper, CAV2, Bordetella CSW RT Real-time PCR bronchiseptica, Parainfluenza) 2 1 1 PCR Profile 11/dogs - “Zoonoses/ d o g s ” Real-time PCR, real- 7 F C , U 1 - 2 g g 9 1 , 5 0 (Leptospirosis , Giardia, time TaqMan® PCR Cryptosporidium) 2 3 0 RT Real-time PCR, PCR Profile 1A/cats “Neurology 1” CSF+EB; only EB Real-time TaqMan® 1 - 2 g g 7 9 , 3 0 (Toxoplasma/FIP) PCR 2 3 9 RT Real-time PCR, PCR Profile 1B/cats “Neurology 2” CSF+EB; effusion Real-time TaqMan® 1 - 2 g g 7 9 , 3 0 (Toxoplasma/FCOV) PCR

2 3 1 PCR Profile 2A/cats “Viral diseases RT Real-time PCR, 1” EB, BM, B/C Real-time TaqMan® 1 - 2 g g (FIP/FELV/FIV) PCR, Real-time PCR 9 7 , 6 0

2 4 0 PCR Profile 2B/cats “Viral diseases RT Real-time PCR, Effusion; EB, BM, 2” Real-time TaqMan® B/C 1 - 2 g g (FCOV/FELV/FIV) PCR, Real-time PCR 9 7 , 6 0 PCR Profile 3/cats “Anemia” 2 3 2 Real-time PCR, real- (hemobartonellosis B/C, BM, EB 1 - 2 g g 9 7 , 6 0 time TaqMan® PCR feline/FELV/FIV) 2 3 3 PCR Profile 4/cats “Ophthalmologic - respiratory” RT Real-time nested B/C, CSW, EB 1 - 2 g g 9 7 , 6 0 (calicivirus/herpesvirus/ PCR, Real-time PCR Chlamidophyla felis) 2 3 4 PCR Profile 5/cats “Filariosis” (Dirofilaria immitis, Dirofilaria E B , B/C Real-time PCR 1 - 2 g g 4 8 , 8 0 r e p e n s ) PCR Profile 6/cats - “Intestinal 2 3 5 Real-time PCR, real- p r o t o z o a ” FC 1 - 2 g g 8 5 , 4 0 time TaqMan® PCR (Cryptosporidium, Giardia) 2 3 6 PCR Profile 7/cats - “Zoonoses/ c a t s ” Real-time PCR, real- F C a n d E B 1 - 2 g g 1 0 9 , 8 0 (, Cryptosporidium, time TaqMan® PCR Giardia, Bartonella spp.) 2 3 7 PCR Profile 8/cats “Hemotropic Mycoplasm” real-time TaqMan®- (M haemophelis, Candidatus M EB 1 - 2 g g 9 7 , 6 0 MGB PCR haemominutum, Candidatus M turicensis)

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2 3 8 PCR Profile PCR 1 / h o r s e s “Piroplasidi” EB Real-time PCR 1 - 2 g g 6 1 , 0 0 (Theileria equi, Babesia caballi) 2 4 1 PCR Profile 2/horses “Reproduction” PCR, RT PCR, real- (EHV1, Streptococcus equi subsp. F / V S , S P time real-time 1 - 2 g g 1 1 5 , 9 0 zooepidemicus, Taylorella TaqMan® PCR equigenitalis,arterite) 2 4 2 PCR Profile 3/horses “Respiratory” PCR, real-time (EHV1, EHV4, Rodococcus NS, OSP, BAL 1 - 2 g g 1 1 5 , 9 0 equi,Streptococcus equi TaqMan® PCR subsp.zooepidemicus and equi) 2 4 3 PCR Profile 1/birds (PBFD,polyomavirus (Pacheco’s EB, FC, CS, T PCR, Real-time PCR 1 - 2 g g 8 5 , 4 0 Disease) 2 4 4 PCR Profile 2/birds (PBFD,polyomavirus (Pacheco’s EB, FC, CS, T PCR, Real-time PCR 1 - 2 g g 9 1 , 5 0 Disease,Chlamydia psittaci) 2 4 5 PCR Profile 3/birds Gene scanning, (PBFD,polyomavirus, Chlamydia psittaci, EB, FC, CS, T 1 5 g g 9 7 , 6 0 Real-time PCR genetic sexing)

GENETIC DISEASES

Matrix analysis for all genetic diseases: EB, 2 X S, 1 X EBS

M a x i m u m P r i c e i n T e s t B r e e d s Analysis t u r n a r o u n e u r o s V A T 8 d t i m e i n c l .

4 6 1 Bullmastiff, English , AD- P R A Sequencing 1 5 g g 6 7 , 1 0 Mastiff (Old English)

5 7 4 Adult Onset Neuropathy (AON)* Cocker Inglese Sequencing 1 5 g g 1 0 0 , 0 0

4 9 3 A l l d o g s b r e e d s Analysis SOD1 gene exon 2 Sequencing 5 - 7 g g 3 6 , 6 0

5 5 9 Bernese Mountain DHPLC, A n a l y s i s S O D 1 g e n e e x o n 1 Heteroduplex 1 0 g g 7 3 , 2 0 analysis 5 5 5 Bernard Soulier Syndrome (BSS) Cocker Spaniel Sequencing 1 5 g g 6 7 , 1 0

5 1 3 Blood Group DNA test All cats breeds Serolog test 1 g 3 6 , 6 0

4 9 6 All cats breeds ( R a g d o l l GeneScanning Blood Group genetic test 1 0 g g 6 7 , 1 0 e x c l u d e d ) + Sequencing

4 2 2 CLAD (Canine Leucocyte Irish Sequencing 1 5 g g 7 3 , 2 0 Adhesion deficiency) American Bulldog, Australian Shepherd, CMR 1 (Canine multifocal Bullmastiff, Cane Corso, 5 7 7 retinopathy) (dogs) Dogue de Bordeaux, Sequencing 1 5 g g 6 7 , 1 0 English Bulldog, English Mastiff, French Bulldog, Great Pyrenee

CMR 2 (Canine multifocal 5 7 8 Coton de Tulear Sequencing 1 5 g g 6 7 , 1 0 retinopathy )

Fragment 4 4 5 CNM (Hereditary Myopathy) Labrador 7 g g 4 8 , 8 0 analysis 4 5 7 Coat colour - A g o u t i All cats breeds Sequencing 1 0 g g 3 6 , 6 0

5 7 0 Coat colour - C h a r c o a l B e n g a l Sequencing 1 0 g g 4 2 , 7 0

4 5 6 Coat colours - All cats breeds Sequencing 1 0 g g 3 6 , 6 0 Cinnamon/Chocolate

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4 5 8 Coat colours - Siamese/Burmese All cats breeds Sequencing 1 0 g g 3 6 , 6 0 c a t s

5 4 4 Coat colour - A m b r a Norwegian Forest Sequencing 1 5 g g 4 2 , 7 0

5 2 3 Coat colour Locus A - A g o u t i All dogs breeds Sequencing 1 0 g g 3 6 , 6 0 (allele Y, TAN, NON AGOUTI) 4 3 3 All dogs breeds Coat colour Locus B Sequencing 1 0 g g 3 6 , 6 0 (Chocolate, Brown,…)

4 3 2 Coat colour Locus E (Yellow, All dogs breeds Real-time 5 - 7 g g 3 6 , 6 0 Apricot,…) TaqMan® PCR 4 9 7 Coat colour Locus Em A l l d o g s b r e e d s Sequencing 1 0 g g 3 6 , 6 0 (Melanistic Mask Allele) 5 7 3 Coat colour Locus H (Harelquin All dogs breeds Sequencing 1 5 g g 3 6 . 6 0 coat colour)

5 2 4 Coat colour Locus K All dogs breeds Sequencing 1 0 g g 3 6 , 6 0 Fragment 4 8 6 Coat colour Tobiano All horses breeds 7 g g 4 2 , 7 0 analysis Australian Shepherd, Border Collie, Collie, English Shepherd,

Lancashire Heeier, Collie Eye Anomaly (CEA)* Sequencing 1 5 g g 6 7 , 1 0 5 5 2 Miniature American Shepherd, Miniature Australian Shepherd, W h i p p e t Conjunctivitis/ Ligneous 6 5 7 M a l t e s e Sequencing 1 5 g g 6 7 , 1 0 membranitis 5 9 4 Copper toxicosis predisposition Labrador retriever Sequencing 1 5 g g 6 7 , 1 0 A T P 7 a 5 9 5 Copper toxicosis predisposition Labrador retriever Sequencing 1 5 g g 6 7 , 1 0 A T P 7 b 9 Miniature Dachshunds, 5 9 1 C o r d 1 - P R A * English Springer S p a n i e l s , Sequencing 1 5 g g 6 7 , 1 0 Curly Coated Retriever Miniature Wire haired 5 5 8 C r d - PRA Dachshund, Standard Wire Sequencing 1 5 g g 9 5 , 0 0 haired Dachshund

4 3 5 C u r l y All dogs breeds Sequencing 1 5 g g 6 7 , 1 0

4 0 5 C y s t i n u r i a Newfoundland, Landseer Sequencing 1 5 g g 6 7 , 1 0 Sequencing 5 3 9 C y s t i n u r i a Miniature 1 5 g g 6 7 , 1 0

Sequencing 5 8 8 C y s t i n u r i a Australian Cattle Dog 1 5 g g 6 7 , 1 0

6 6 6 Degenerative Myelopathy * All dogs breeds 2 1 g g 9 5 , 0 0

6 6 7 Degenerative Myelopathy All dogs breeds 2 1 g g 1 2 2 , 0 0 L a b o k l i n * Storage of a 6 0 2 DNA Banking All dogs breeds 1 - 2 g g 1 2 , 2 0 sample 4 7 2 Dilution coat colours - d o g s All dogs breeds Sequencing 1 0 g g 6 7 , 1 0

4 6 7 Dilution coat colours - c a t s All cats breeds GeneScanning 1 0 g g 4 8 , 8 0

5 2 6 Dry Eye Curly Coat Syndrome Cavalier King Charles (CCS) S p a n i e l GeneScanning 1 5 g g 6 7 , 1 0

Labrador, Pembroke Welsh Corgi, Old English Sheepdog, German

Wirehaired Pointer, English 4 5 0 EIC (Exercise - I n d u c e d Cocker Spaniel, Curly Sequencing 7 - 1 0 g g 7 3 , 2 0 C o l l a p s e ) Coated Retriever, Chesapeake Bay Retriever, Boykin Spaniel, Bovaro delle fiandre, American Cocker Spaniel

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German Pointer, German Epidermolysis Bullosa Shorthaired Pointer, Fragment 4 7 9 7 g g 6 7 , 1 0 Junctional (EBJ) German Wirehaired analysis Pointer, Golden Retriever 5 2 5 Episodic Falling (EF)* Cavalier King Charles 6 7 , 1 0 GeneScanning 1 5 g g S p a n i e l

Beagle, Alaskan Klee Kai , Factor VII D e f i c i e n c y Sequencing 1 5 g g 6 7 , 1 0 4 0 6 Scottish Deerhound

4 0 9 Factor XI Deficiency Kerry Blue Sequencing 1 5 g g 6 7 , 1 0

4 8 5 Familial Nephropathy English Cocker Spaniel Sequencing 1 0 g g 6 7 , 1 0

5 3 8 Forensic Genetic Profile Contact lab GeneScanning 1 5 g g 1 2 2 , 0 0

4 5 9 Forensic Genetic Profile ISAG All horses breeds GeneScanning 1 5 g g 4 8 , 8 0

4 1 0 Fucosidosis English Springer Spaniel Sequencing 1 5 g g 6 7 , 1 0

5 3 7 Furnishing All dogs breeds Sequencing 1 0 g g 3 6 , 6 0

4 6 8 Burmese, Domestic Gangliosidosis GM1 Sequencing 1 5 g g 6 7 , 1 0 Shorthair, Siamese,

4 7 8 Gangliosidosis GM2 B u r m e s e Sequencing 1 5 g g 6 7 , 1 0

4 7 0 Domestic Shorthair Gangliosidosis GM2 Sequencing 1 5 g g 6 7 , 1 0

4 6 9 Japanese Shorthair Gangliosidosis GM2 Sequencing 1 5 g g 6 7 , 1 0

5 3 5 Shiba Inu, Alaskan Husky Gangliosidosis type 1 GM1 GeneScanning 1 5 g g 6 7 , 1 0

5 4 0 Gangliosidosis type 1 GM 1* Portuguese Sequencing 1 5 g g 6 7 , 1 0

4 6 0 Genetic Profile panel ISAG All cats breeds GeneScanning 1 5 g g 4 8 , 8 0 4 6 5 Genetic Profile panel ISAG 2008 All dogs breeds GeneScanning 1 5 g g 4 8 , 8 0 10 5 8 9 Genetic Profile* All parrot breeds 1 5 g g 4 8 , 8 0

4 2 3 Glycogen Storage Disease All dogs breeds Sequencing 1 5 g g 6 7 , 1 0 (GSD) type IA Glycogen Storage Disease 4 1 9 Norwegian Forest cats GeneScanning 1 5 g g 6 7 , 1 0 (GSD) type IV 5 2 8 G R P R A 1 Golden Retriever Sequencing 1 5 g g 6 7 , 1 0

5 6 4 G R P R A 2 * Golden Retriever 1 5 g g 8 5 . 4 0

5 6 8 Hemophilia B Rhodesian Ridgeback Sequencing 1 5 g g 6 7 . 1 0

4 4 3 Hereditary Cataracts Boston Terrier, Australian 7 3 , 2 0 Shepherd, Staffordshire GeneScanning 1 0 g g Bull Terrier 5 2 2 Hereditary Nasal Parakeratosis Labrador Retriever 1 5 g g 1 3 0 , 5 4 ( H N P K ) * 5 0 9 Hypercalemic Periodic All horses breeds Sequencing 1 5 g g 6 7 , 1 0 Paralysis (HYPP) 5 1 8 Hypertrophic Cardiomyopathy M a i n e C o o n Real-time 5 - 7 g g 4 2 , 7 0 ( H C M ) A 3 1 P TaqMan® PCR 4 2 1 Hypertrophic Cardiomyopathy M a i n e C o o n Sequencing 1 5 g g 5 4 , 9 0 ( H C M ) A31P e A74T Real-time 4 5 4 Hypertrophic Cardiomyopathy R a g d o l l 5 - 7 g g 4 2 , 7 0 TaqMan® PCR 5 7 6 Hyperuricosuria All dogs breeds Sequencing 1 5 g g 6 7 , 1 0

4 1 1 Hypothyroidism Terrier GeneScanning 1 5 g g 6 7 , 1 0

5 4 3 I c h t h y o s i s Golden retriever Sequencing 1 5 g g 6 7 , 1 0 I m e r s l u n d - Gräsbeck syndrome 5 4 2 B e a g l e GeneScanning 1 0 g g 7 3 , 2 0 (IGS ) I m e r s l u n d - Gräsbeck syndrome 5 8 5 Border Collie GeneScanning 1 0 g g 6 7 , 1 0 (IGS ) Juvenile Laryngeal Paralysis Rottweiler, Balck Russian Sequencing 1 5 g g 7 3 , 2 0 5 8 2 and Polyneuropathy (JLPP) T e r r i e r DHPLC, 5 0 8 Juvenile Epilepsy (JE) Lagotto Romagnolo 7 g g 6 7 , 1 0 Heteroduplex

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analysis

5 6 7 Juvenile Myoclonic Epilepsy Rhodesian Ridgeback Sequencing 1 5 g g 6 7 , 1 0 (JME)

4 7 6 L - 2 - HGA (hydroxyglutaric Staffordshire Bull Terrier Sequencing 1 0 g g 6 7 , 1 0 a c i d u r i a )

Jack Russell Terrier, Parson Late onset ataxia (LOA) Sequencing 1 5 g g 7 3 , 2 0 5 8 0 Russell Terrier All dogs breeds (than for Long coat disease GeneScanning Eurasier, Akita, Afghan 1 0 g g 6 7 , 1 0 4 9 4 + Sequencing h o u n d ) GeneScanning 4 5 5 Long coat disease All cats breeds 1 0 g g 6 7 , 1 0 + Sequencing 5 4 5 Lysosomal storage disease Lagotto romagnolo Sequencing 1 0 g g 6 7 , 1 0 (LSD)

5 8 6 Macrothrombocytopenia Cavalier King Charles Sequencing 1 5 g g 6 7 , 1 0

Australian Shepherd, Bobtail, Border Collie, G e r m a n Shepherd, Long -

/Shorthair Collie, MDR1 Gene Defect ( Longhaired Whippet, GeneScanning 7 - 1 0 g g 7 3 , 2 0 Sensitivity) 4 4 4 McNab, Shetland Sheepdog, Silken Windhound, White S h e p h e r d 5 5 0 Labrador Retriever, Malignant Hyperthermia (RYR) Sequencing 1 5 g g 7 3 , 2 0 Pointer, GreyHound

4 2 0 Mannosidosis P e r s i a n GeneScanning 1 5 g g 6 7 , 1 0

4 2 7 Muscular dystrophy L a n d s e e r Sequencing 1 5 g g 6 7 , 1 0

5 7 5 Muscular dystrophy Golden Retriever Sequencing 1 5 g g 6 7 , 1 0

Cavalier King Charles 11 Muscular dystrophy Sequencing 1 5 g g 6 7 , 1 0 4 3 4 S p a n i e l

5 3 2 Myotonia Congenita Australian Cattle Dog Sequencing 1 5 g g 7 3 , 2 0

4 1 5 Myotonia Congenita M i n i a t u r e S c h n a u z e r Sequencing 1 5 g g 6 7 , 1 0 Mucopolysaccharidosis (MPS) 4 1 2 S c h i p p e r k e Sequencing 1 5 g g 6 7 , 1 0 IIIB Mucopolysaccharidosis (MPS) 4 1 3 Miniature Pinscher S e q u e n c i n g 15 gg 6 7 , 1 0 VI 4 5 1 Mucopolysaccharidosis (MPS) Siamese, Domestic S e q u e n c i n g 1 5 g g 6 7 , 1 0 VI S h o r t h a i r Mucopolysaccharidosis (MPS) 4 5 2 Domestic Shorthair Sequencing 1 5 g g 6 7 , 1 0 V I I 4 1 4 Mucopolysaccharidosis (MPS) , Mixed Sequencing 15 gg 6 7 , 1 0 VII b r e e d

5 1 5 M u s l a d i n - Lueke Syndrome (MLS) B e a g l e Sequencing 1 5 g g 6 7 , 1 0

5 9 2 Myostatin Deficiency* W h i p p e t 1 5 g g 7 3 , 2 0

5 7 9 N a r c o l e p s y D a c h s h u n d Sequencing 1 5 g g 6 7 , 1 0

5 9 0 N a r c o l e p s y D o b e r m a n n Sequencing 1 5 g g 6 7 , 1 0

5 3 4 N a r c o l e p s y Labrador Retriever Sequencing 1 5 g g 6 7 , 1 0

5 2 7 Neonatal Cerebellar Cortical B e a g l e GeneScanning 1 5 g g 6 7 , 1 0 Degeneration (NCCD) 5 3 3 Neuronal Ceroid Lipofuscinosis Border Collie Sequencing 1 5 g g 6 7 , 1 0 5 ( N C L - 5) 5 3 0 Neuronal Ceroid Lipofuscinosis English Setter Sequencing 1 5 g g 6 7 , 1 0 8 ( N C L - 8) 4 2 8 Neuronal Ceroid Lipofuscinosis American Staffordshire 1 5 g g 6 7 , 1 0 (NCL - A)* T e r r i e r 4 3 9 Osteo chondrodystrophia All cats breeds Sequencing 1 5 g g 6 7 , 1 0 d e f o r m a n s

5 3 2 Osteogenesis Imperfecta D a c h s h u n d Sequencing 1 5 g g 6 7 , 1 0

5 1 0 Overo Lethal White Foal All horses breeds Sequencing 1 5 g g 6 7 , 1 0

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Syndrome (OLWS)

American Cocker Spaniel, Phosphofructokinase deficiency English Cocker Spaniel, 4 1 6 Sequencing 1 5 g g 6 7 , 1 0 (PFKD) English Springer Spaniel, W h i p p e t German Shepherd, 4 2 9 P i t u i t a r y D w a r f i s m Czechoslovakian Wolfdog, GeneScanning 1 0 g g 6 7 , 1 0 Saarloos Wolfdog 4 1 7 PK Deficiency (Pyruvate Kinase Beagle, Labrador, Pug Deficiency) Sequencing 1 0 g g 6 7 , 1 0

6 5 5 PK Deficiency (Pyruvate Kinase B a s e n j i Deficiency) Sequencing 1 0 g g 6 7 , 1 0

6 5 6 PK Deficiency (Pyruvate Kinase West Highland White Sequencing 1 0 g g 6 7 , 1 0 Deficiency) T e r r i e r Abyssinian, Bengala, Domestic Shorthair, Domestic Longhair, PK Deficiency (Pyruvate Kinase , La Perm, Sequencing 1 0 g g 6 7 , 1 0 D e f i c i e n c y ) 4 5 3 , N o r w e g i a n Forest, , Savannah, Siberian, Singapura, Somali Angora, , British S h o r t - e Longhair, , Colourpoint, R e a l - t i m e 4 0 0 Polycystic Kidney Disease , Maine T a q M a n ® 5 - 7 g g 3 6 , 6 0 (PKD) Coon, Persian and related PCR b r e e d s , , , , Siamese

5 9 6 Polyneuropathy* G r e y h o u n d 1 5 g g 6 7 , 1 0

5 1 9 Progressive retinal atrophy All dogs breeds 1 5 g g 9 5 , 0 0 ( p r c d - PRA)* 12 5 6 0 P R A 1 P a p i l l o n Sequencing 1 5 g g 7 3 , 2 0

4 6 3 PRA - r c d 1 Irish setter Sequencing 1 5 g g 1 4 6 , 4 0

4 6 4 PRA - r c d 3 Cardigan Welsh Corgi GeneScanning 1 5 g g 1 4 6 , 4 0

5 8 4 PRA generalized* Schapendoes 1 5 g g 7 0 , 0 0

6 5 8 Primary open angle glaucoma Basset Fauve PCR 1 5 g g 6 7 , 1 0 (POAG)

6 5 9 Primary open angle glaucoma Basset PCR 1 5 g g 6 7 , 1 0 (POAG)

5 6 9 Primary open angle glaucoma B e a g l e PCR 1 5 g g 6 7 , 1 0 (POAG)

A m e r . Eskimo Dog, Amer . Hairless Terrier, Austr . C a t t l e D o g, C h i n e s e

Crested Dog, Chinese Foo Dog, Fox Terrier, Jack Russell Terrier, Jagdterrier, Lakeland Terrier, Lancashire Heeler, Lucas Terrier, Miniature Bull D H P L C , 5 0 6 Terrier, Norfolk Terrier, Primary Lens Luxation (PLL) Heteroduple 7 g g 6 7 , 1 0 Norwich Terrier, Parson x a n a l y s i s Russell Terrier, Patterdale Terrier, Pug Dog, Rat Terrier, Sealyham Terrier, Teddy Roosevelt Terrier, Tenterfield Terrier, Tibet Terrier, Toy Fox Terrier, Italian Fox Terrier, Welsh Terrier, Westphalia Terrier, Yorkshire Terrier

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Abyssinian, , , Balinese, Bengal,

Colorpoint Shorthair, Progressive Retinal Atrophy 4 7 1 , Javanese, S e q u e n c i n g 1 5 g g 6 7 , 1 0 ( r d A c ) Munchkin, Ocicat, , , Siamese, Singapura, Somalo, Tonkinese

4 2 6 RDY Early Onset with D y s p l a s i a A b y s s i n i a n Sequencing 1 5 g g 6 7 , 1 0

4 4 6 Renal Cystadenocarcinoma German Shepherd Sequencing 1 5 g g 7 3 , 2 0

5 4 8 Resistance to phenobarbitol Contact lab Sequencing 1 5 g g 7 3 , 2 0 g e n e A B C B 1 5 5 6 Research genetic marker Blue All dogs breeds Fragment 1 5 g g 7 3 , 2 0 M e r l e analysis 4 0 1 All parrot breeds Sex determination Genescanning 1 5 g g 4 6 , 9 7

Severe Combined Immune - 4 1 8 Welsh corgi GeneScanning 1 5 g g 6 7 , 1 0 deficiency (SCID) Severe Combined Immune - 6 2 0 All horses breeds Sequencing 1 5 g g 6 7 , 1 0 deficiency (SCID) 5 7 2 Skeletal Dysplasia 2 Labrador Retriever GeneScanning 1 5 g g 6 7 , 1 0

Australian shepherd, Austrian Pinscher, Australian Stumpy Tail

Cattle Dog, Bourbonnais Pointer, Brazilian Terrier, Brittany Spaniel, Croatian Sheepdog, Danish Farmdog, Swedish Short Tail (Bobtail) Sequencing 1 5 g g 6 7 , 1 0 5 1 1 Farmdog, Jack Russell Terrier, Karelian Dog, Mudi, Polish Lowland 13 S h e e p d o g , P y r e n e a n Shepherd, Savoy Sheepdog, Schipperke, Spanish Water Dog, Swedish Vallhund

4 9 5 Spinal Muscular Atrophy (SMA) M a i n e C o o n Sequencing 7 g g 4 8 , 8 0

Jack Russell Terrier, Parson Spinocerebellar ataxia (SCA) Russell Terrier, Tenterfield 5 8 1 Sequencing 1 5 g g 6 7 , 1 0 Terrier, Toy Fox Terrier, Smooth haired fox terrier

5 3 1 Trapped Neutrophil Syndrome Border Collie Sequencing 1 5 g g 6 7 , 1 0 (TNS)

4 7 7 Thrombopathy Basset Hound Genescanning 15 gg 6 7 , 1 0

4 7 7 Thrombopathy Eskimo Sequencing 1 5 g g 6 7 , 1 0

5 4 1 Thrombopathy L a n d s e e r Sequencing 1 5 g g 6 7 , 1 0

Doberman, Bernese, Coton de Tuler, Pinscher, Kerry Blue Terrier, Manchester Genotyping 4 4 7 Von Willebrand disease type I 5 - 7 g g 7 3 , 2 0 Terrier, Pembroke Welsh TaqMan®MGB Corgi, Poodle, Shetland s h e e p d o g

Deutsch Drahthaar, German Shorthaired 4 4 8 Von Willebrand disease type II Sequencing 1 5 g g 7 3 , 2 0 Pointer, German Wirehaired Pointer

4 4 9 Von Willebrand disease type III Scottish Terrier GeneScanning 1 5 g g 7 3 , 2 0

4 6 6 Von Willebrand disease type III Shetland Sheepdog GeneScanning 1 5 g g 7 3 , 2 0

4 4 1 X - linked PRA 1 Samoyed, S.Husky GeneScanning 1 5 g g 1 4 6 , 4 0

TaqMan® is a registered trademark of the Roche Molecular System

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GENETIC DISEASE PROFILES for Dogs and Cats M a x i m u m P r i c e i n T e s t t u r n a r o u n e u r o s V A T d t i m e i n c l . Profile Australian Sheperd (CEA* + Sod1 Gene Exon 2 + MDR1 + Prcd - PRA + Malignant Hyperthermia 1 5 g g 1 8 0 , 0 0 + hereditary cataract) P r o f i l e - Lagotto Romagnolo ( J u v e n i l e epilepsy (JE) + Lysosomal Storage 5 - 7 g g 1 1 0 , 0 0 Disease (LSD) + Furnishing) P r o f i l e - B e a g l e (Musladin Lueke Syndrome (MLS) + Factor VII Deficiency + Neonatal 1 5 g g 1 2 6 , 0 0 Cerebellar Cortical Degeneration (NCCD) + POAG + IGS + PK Deficiency) P r o f i l e - Saarloos Wolfdog 1 5 g g 1 2 6 , 0 0 (Sod 1 Gene Exon 2 + Dwarfism) P r o f i l e - Dobermann 1 1 5 g g 1 2 6 , 0 0 (Sod1 Gene Exon 2 + Coat dilution + Von Willebran I Disease) P r o f i l e - Dobermann 2 1 5 g g 9 1 , 5 0 (Coat dilution + Von Willebran I Disease) P r o f i l e - Dobermann 3 1 5 g g 1 2 6 , 0 0 (Coat dilution + Von Willebran I Disease + Locus B) P r o f i l e - Lupo Cecoslovacco 1 1 5 g g 8 5 , 0 0 (Sod1 Gene Exon 2 + Dwarfism) P r o f i l e - Lupo Cecoslovacco 2 1 5 g g 1 1 0 , 0 0 (Sod1 Gene Exon 2 + Dwarfism + Long coat disease) P r o f i l e - Cavalier King Charles Spaniel - Dry Eye Curly Coat Syndrome 1 5 g g 8 5 , 0 0 (CCS) + Episodic Falling (EF) P r o f i l e - English Cocker Spaniel (Familial Nephropathy (FN) + Prcd - P R A * + 1 5 g g 1 6 5 , 0 0 Bernard Soulier Syndrome (BSS)) 14 P r o f i l e - Golden Retriever (GRPRA1 + GRPRA2* + Prcd - P R A * + S o d 1 G e n e 1 5 g g 1 8 0 , 0 0 E x o n 2 + Ichthyosis) P r o f i l e - Labrador Retriever ( C N M + Sod1 Gene Exon 2 + EIC + HNPK* + 1 5 g g 1 8 0 , 0 0 P r c d - PRA* + Dwarfism SD2) Profile Collie 1 5 g g 1 2 6 , 0 0 (Gene Sod1 Exon 2 + CEA* + MDR1)

P r o f i l e - Border Collie 1 5 g g 1 2 6 , 0 0 (Sod1 Gene Exon 2+ MDR1 + CEA* + IGS + NCL + TNS)

P r o f i l e - Australian Shepherd (CEA* + Sod1 Gene Exon 2 + hereditary cataract + MDR1 + Malignant 1 5 g g 1 8 0 , 0 0 Hyperthermia + Prcd - PRA*) P r o f i l e - Schipperke 1 ( M D R 1 + MPS I I I B + Sod1 Gene Exon 2 + P r c d - Pra* + Bobtail + DNA 1 5 g g 2 2 0 , 0 0 B a n k i n g ) P r o f i l e - Schipperke 2 1 5 g g 1 1 0 , 0 0 (MDR1 + MPS IIIB) P r o f i l e - Schipperke 3 1 5 g g 1 1 5 , 0 0 (MDR1 + MPS IIIB + DNA Banking) Profile Rhodesian Ridgeback 1 5 g g 1 1 0 , 0 0 ( Sod1 Gene Exon 2 + + JME + Hemophilia B) Profile Staffordshire Bull Terrier 1 5 g g 1 1 0 , 0 0 (L2H2 + Hereditary Cataracts) Profile Landseer 1 5 g g 1 2 6 , 0 0 ( Sod1 Gene Exon 2 + Muscular dystrophy + Thrombopathy + Cystinuria) Genetic profile 1 - c a t s 1 5 g g 1 1 0 , 0 0 PKD + PKDef + HCM 1 mutation (Maine Coon or Ragdoll)

Genetic profile 2 - c a t s 1 5 g g 1 2 0 , 0 0 PKDef + PKD + Spinal Muscular Atrophy (SMA)

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Genetic profile 3 - c a t s 1 5 g g 9 5 , 0 0 Serologic blood type grouping + genetic blood group typing

*Test carried out at a partner laboratory

URGENCY: test carried out in 5 working days (+ 30% over the cost of the analysis). Analyses sent to partner laboratories are excluded.

VETERINARY MOLECULAR-ONCOLOGY DESEASES P r i c e i n M a x i m u m e u r o s T e s t Abbreviations Analysis turnaround V A T t i m e i n c l . 6 1 1 Minimal residual d i s e a s e ( M R D ) B / C , BM, EB Real-time PCR 2 g g 4 6 , 9 7

6 1 6 Clonality test - B a n d T cell receptors – P C R + B / C , BM, EB 1 5 g g 1 2 2 , 0 0 c a t s Genescanning 4 0 3 Clonality test - B a n d T cell receptors - P C R + B / C , BM, EB 1 5 g g 1 2 2 , 0 0 d o g s GeneScanning 4 4 2 ITD c - k i t P o i n t Mutation exon 11 in P C R + c a n i n e m a s t o c y toma (ITD, inse r t i o n s B / C , EB 1 0 g g 8 5 , 4 0 GeneScanning and deletions ) 4 7 3 P C R + I T D c - k i t P o i n t Mutation exon 8 in B / C , EB GeneScanning+ 1 0 g g 8 5 , 4 0 canine mastocytoma S e q u e n c i n g 4 7 4 I T D c - k i t P o i n t Mutation exon 9 in B / C , EB P C R + S e q u e n c i n g 1 0 g g 8 5 , 4 0 canine mastocytoma

4 2 9 I T D c - k i t P o i n t Mutation exon 17 i n B / C , EB P C R + S e q u e n c i n g 1 0 g g 8 5 , 4 0 15 canine mastocytoma

4 7 5 P C R + P a n e l o f c - k i t receptor mutations - B / C , EB GeneScanning+ 1 5 g g 1 4 6 , 4 0 c a n i n e m a s t o c y t o m a e x ons 8 , 9 , 1 1 , 1 7 S e q u e n c i n g 4 9 8 I T D c - k i t P o i n t Mutation exon 11 in P C R + feline mastocytoma (ITD, insertions and B / C , EB GeneScanning + 1 0 g g 8 5 , 4 0 d e l e t i o n s ) s e q u e n c i n g 4 9 9 I T D c - k i t P o i n t Mutation exon 8 in feline mastocytoma (ITD, insertions and B / C , EB P C R + S e q u e n c i n g 1 0 g g 8 5 , 4 0 d e l e t i o n s ) 5 0 4 I T D c - k i t P o i n t Mutation exon 9 in feline mastocytoma (ITD, insertions and B / C , EB P C R + S e q u e n c i n g 1 0 g g 8 5 , 4 0 d e l e t i o n s ) 5 0 5 P C R + P a n e l o f c - kit receptor mutations - f e l i n e B / C , EB GeneScanning+ 1 5 g g 1 4 6 , 4 0 mastocytoma exons 8, 9, 11 S e q u e n c i n g 6 1 2 Clonality typing B / C , BM, EB S e q u e n c i n g 1 5 g g 9 3 , 9 4 6 6 8 Mutation gene braf of transitional cells B / C , EB PCR + Sequencing 1 5 g g 6 7 , 1 0 in the urinary bladder

URGENZA: test carried out in 5 working days (+ 30% over the cost of the analysis). Analyses sent to partner laboratories are excluded.

SEROLOGY-IMMUNOFLUORESCENCE DISEASES

M a x i m u m P r i c e i n T e s t Abbreviations Analysis t u r n a r o u n d e u r o s V A T t i m e i n c l .

3 1 0 A n a t e s t SE, PL IFA 1 g 3 6 , 6 0 1 0 9 Anaplasma phagocytophilum (HGE) SE, PL IFA 1 g 3 6 , 6 0 I g G

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1 1 0 Anaplasma phagocytophilum (HGE) SE, PL IFA 1 g 3 6 , 6 0 I g M 1 0 3 Babesia caballi IgG SE, PL IFA 1 g 3 6 , 6 0 1 1 7 B a b e s i a caballi IgM SE, PL IFA 1 g 3 6 , 6 0 1 1 5 Babesia canis IgG SE, PL IFA 1 g 3 6 , 6 0 1 0 2 Babesia equi IgG SE, P L IFA 1 g 3 6 , 6 0 1 0 6 Babesia equi IgM SE, P L IFA 1 g 3 6 , 6 0 2 5 1 B a b e s i a m d r i I g G SE, P L IFA 1 g 3 6 , 6 0 2 5 2 Babesia gibsoni IgM SE, P L IFA 1 g 3 6 , 6 0 1 2 7 Bartonella henselae IgG SE, P L IFA 1 g 3 6 , 6 0 1 3 0 Bartonella henselae IgM SE, P L IFA 1 g 3 6 , 6 0 1 0 4 Borrelia burgdorferii IgG SE, P L IFA 1 g 3 0 , 5 0 1 0 5 Borrelia burgdorferii IgM SE, P L IFA 1 g 3 0 , 5 0

1 3 2 Canine Herpesvirus IgG SE, P L IFA 1 g 4 8 , 8 0 1 1 8 D i s t e m p e r I g G SE, P L , CSF IFA 1 g 3 6 , 6 0 1 1 9 D i s t e m p e r I g M SE, P L , CSF IFA 1 g 3 6 , 6 0 1 0 7 Ehrlichia canis IgG SE, P L IFA 1 g 3 6 , 6 0 1 0 8 Ehrlichia canis IgM SE, P L IFA 1 g 3 6 , 6 0 1 3 3 Equine Herpesvirus 1,4 IgG SE, P L IFA 1 g 4 8 , 8 0 1 1 6 F I P V I g G SE, P L IFA 1 g 3 0 , 5 0

1 0 1 Leishmania IgG SE, P L IFA 1 g 3 1 , 7 2

1 2 2 Neorickettsia risticii IgG SE, P L IFA 1 g 3 6 , 6 0 1 1 3 Neospora caninum IgG SE, P L IFA 1 g 3 6 , 6 0 1 1 4 Neospora caninum IgM SE, P L IFA 1 g 3 6 , 6 0 16 1 2 8 C a n i n e Parvovirus IgG SE, P L IFA 1 g 3 6 , 6 0 1 3 1 Rickettsia conorii IgG SE, P L IFA 1 g 3 0 , 5 0 1 3 4 Rickettsia conorii IgM SE, P L IFA 1 g 3 0 , 5 0 1 2 0 Rickettsia rickettsii IgG SE, P L IFA 1 g 3 0 , 5 0 1 2 1 Rickettsia rickettsii IgM SE, P L IFA 1 g 3 0 , 5 0 1 1 1 Toxoplasma gondii IgG SE, P L IFA 1 g 3 0 , 5 0 1 1 2 Toxoplasma gondii IgM SE, P L IFA 1 g 3 0 , 5 0

SEROLOGY-IMMUNOFLUORESCENCE PROFILE DISEASES

M a x i m u m P r i c e i n T e s t Abbreviations Analysis turnaround e u r o s V A T t i m e i n c l .

3 0 4 D i s t e m p e r I g G - I g M SE, PL IFA 2 g g 6 4 , 0 5 3 0 5 Neospora caninum IgG - I g M SE, PL IFA 2 g g 6 4 , 0 5 3 5 4 Serology profile “Vaccination / d o g s ” SE, PL IFA 2 g g 6 4 , 0 5 Parvovirus – D i s t e m p e r I g G 3 0 1 Serology profile 1/ d o g s “ A r t h r o p o d - borne diseases ” SE, PL IFA 2 g g 8 7 , 8 4 (Leishmania, Ehrlichia canis, Rickettsia rickettsii) 3 0 2 S e r o l o g y p r o f i l e 2 / d o g s “ T i c k - b o r n e d i s e a s e s ” SE, PL IFA 2 g g 8 7 , 8 4 (Babesia canis/Ehrlichia canis / Rickettsia ricketsii)

3 0 3 Serology profile 3/ d o g s “ Neurological ”

( D i s t e m p e r , Toxoplasma gondii, SE, PL IFA 2 g g 8 7 , 8 4 Neospora caninum)

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3 5 1 Serology profile 1 A / h o r s e s “Piroplasmosi s ” SE, PL IFA 2 g g 6 4 , 0 5 (Babesia equi IgG, Babesia caballi IgG) 3 3 1 Serology profile 1B/ h o r s e s “Piroplasmosi s 2 ” SE, PL IFA 2 g g 9 1 , 5 0 (Babesia equi IgG e IgM, Babesia caballi IgG a n d I g M ) 3 5 2 Serology profile 2/ h o r s e s “ T i c k - b o r n e d i s e a s e s ” SE, PL IFA 2 g g 8 8 , 6 9 (Babesia equi IgG, Babesia caballi IgG, Anaplasma phagocytophilum IgG) 3 0 6 Toxoplasma gondii IgG - I g M SE, PL IFA 2 g g 5 1 , 2 4

17

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